TreeWAS – Variant ID: rs29218

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	0.999	0.001	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.997	0.003	0.000
L40-L45 Papulosquamous disorders	0.997	0.003	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.996	0.004	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.995	0.005	0.000
N13 Obstructive and reflux uropathy	0.994	0.006	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.992	0.008	0.000
N10-N16 Renal tubulo-interstitial diseases	0.992	0.008	0.000
Chapter XIV Diseases of the genitourinary system	0.991	0.009	0.000
N00-N08 Glomerular diseases	0.990	0.010	0.000
K51 Ulcerative colitis	0.000	0.011	0.989
M05-M14 Inflammatory polyarthropathies	0.988	0.012	0.000
E16 Other disorders of pancreatic internal secretion	0.986	0.014	0.000
E10.1 With ketoacidosis	0.986	0.014	0.000
M07 Psoriatic and enteropathic arthropathies	0.985	0.015	0.000
M07.3 Other psoriatic arthropathies	0.983	0.017	0.000
E16.2 Hypoglycaemia, unspecified	0.983	0.017	0.000
E10.3 With ophthalmic complications	0.979	0.021	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.021	0.979
N08 Glomerular disorders in diseases classified elsewhere	0.978	0.022	0.000
D80-D89 Certain disorders involving the immune mechanism	0.975	0.025	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.029	0.971
E83.1 Disorders of iron metabolism	0.000	0.036	0.964
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.963	0.037	0.000
E10.2 With renal complications	0.962	0.038	0.000
E14 Unspecified diabetes mellitus	0.962	0.038	0.000
K50-K52 Noninfective enteritis and colitis	0.049	0.039	0.913
E11 Non-insulin-dependent diabetes mellitus	0.957	0.043	0.000
D86 Sarcoidosis	0.955	0.045	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.954	0.046	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.954	0.046	0.000
N04 Nephrotic syndrome	0.950	0.050	0.000
E10.4 With neurological complications	0.950	0.050	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.947	0.053	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.943	0.057	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.942	0.058	0.000
M60-M63 Disorders of muscles	0.942	0.058	0.000
D60-D64 Aplastic and other anaemias	0.940	0.060	0.000
M86-M90 Other osteopathies	0.938	0.062	0.000
K51.4 Pseudopolyposis of colon	0.000	0.067	0.933
M07.36 Other psoriatic arthropathies (Lower leg)	0.933	0.067	0.000
M20-M25 Other joint disorders	0.931	0.069	0.000
D86.9 Sarcoidosis, unspecified	0.926	0.074	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.924	0.076	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.921	0.079	0.000
K50 Crohn's disease [regional enteritis]	0.002	0.086	0.912
M07.39 Other psoriatic arthropathies (Site unspecified)	0.913	0.087	0.000
M62 Other disorders of muscle	0.907	0.093	0.000
K50.9 Crohn's disease, unspecified	0.000	0.097	0.903
E11.5 With peripheral circulatory complications	0.900	0.100	0.000
E14.3 With ophthalmic complications	0.898	0.102	0.000
N04.9 Unspecified	0.897	0.103	0.000
K51.8 Other ulcerative colitis	0.000	0.104	0.896
N08.5 Glomerular disorders in systemic connective tissue disorders	0.886	0.114	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.886	0.114	0.000
M35 Other systemic involvement of connective tissue	0.876	0.124	0.000
Chapter I Certain infectious and parasitic diseases	0.872	0.128	0.000
N11 Chronic tubulo-interstitial nephritis	0.870	0.130	0.000
B35-B49 Mycoses	0.870	0.130	0.000
B37 Candidiasis	0.868	0.132	0.000
M62.8 Other specified disorders of muscle	0.868	0.132	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.133	0.867
N25-N29 Other disorders of kidney and ureter	0.864	0.136	0.000
M35.0 Sicca syndrome [Sjogren]	0.864	0.136	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.137	0.863
N05 Unspecified nephritic syndrome	0.863	0.137	0.000
I73.9 Peripheral vascular disease, unspecified	0.861	0.139	0.000
K51.5 Mucosal proctocolitis	0.000	0.140	0.860
L80-L99 Other disorders of the skin and subcutaneous tissue	0.860	0.140	0.000
M89 Other disorders of bone	0.859	0.141	0.000
D64 Other anaemias	0.859	0.141	0.000
I73 Other peripheral vascular diseases	0.858	0.142	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.858	0.142	0.000
K90 Intestinal malabsorption	0.855	0.145	0.000
E14.5 With peripheral circulatory complications	0.854	0.145	0.000
Q00-Q07 Congenital malformations of the nervous system	0.849	0.151	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.848	0.152	0.000
M25 Other joint disorders, not elsewhere classified	0.847	0.153	0.000
E11.1 With ketoacidosis	0.847	0.153	0.000
I74 Arterial embolism and thrombosis	0.841	0.159	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.839	0.161	0.000
M86 Osteomyelitis	0.838	0.162	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.836	0.164	0.000
M11 Other crystal arthropathies	0.835	0.165	0.000
L40.0 Psoriasis vulgaris	0.830	0.170	0.000
C18.7 Sigmoid colon	0.825	0.175	0.000
M21 Other acquired deformities of limbs	0.825	0.175	0.000
E11.6 With other specified complications	0.824	0.176	0.000
C18 Malignant neoplasm of colon	0.823	0.177	0.000
B37.9 Candidiasis, unspecified	0.820	0.180	0.000
E11.2 With renal complications	0.820	0.180	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.819	0.181	0.000
B37.8 Candidiasis of other sites	0.818	0.182	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.816	0.184	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.815	0.185	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.813	0.187	0.000
D64.9 Anaemia, unspecified	0.813	0.187	0.000
E07 Other disorders of thyroid	0.811	0.189	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.809	0.191	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.806	0.194	0.000
D62 Acute posthaemorrhagic anaemia	0.805	0.195	0.000
L40.1 Generalised pustular psoriasis	0.803	0.197	0.000
M24 Other specific joint derangements	0.803	0.197	0.000
Chapter II Neoplasms	0.802	0.198	0.000
M12 Other specific arthropathies	0.801	0.199	0.000
D61 Other aplastic anaemias	0.800	0.200	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.799	0.201	0.000
M31 Other necrotising vasculopathies	0.799	0.201	0.000
D55-D59 Haemolytic anaemias	0.799	0.201	0.000
M21.0 Valgus deformity, not elsewhere classified	0.797	0.203	0.000
E13 Other specified diabetes mellitus	0.796	0.204	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.796	0.204	0.000
Chapter VI Diseases of the nervous system	0.794	0.206	0.000
C15-C26 Malignant neoplasms of digestive organs	0.792	0.208	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.791	0.209	0.000
G35 Multiple sclerosis	0.791	0.209	0.000
N26 Unspecified contracted kidney	0.790	0.210	0.000
M10 Gout	0.790	0.210	0.000
K50.1 Crohn's disease of large intestine	0.000	0.210	0.789
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.789	0.211	0.000
M15-M19 Arthrosis	0.787	0.213	0.000
E10.6 With other specified complications	0.785	0.215	0.000
D86.0 Sarcoidosis of lung	0.783	0.217	0.000
B37.0 Candidal stomatitis	0.781	0.219	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.780	0.220	0.000
D83 Common variable immunodeficiency	0.780	0.220	0.000
E11.7 With multiple complications	0.780	0.220	0.000
Chapter IX Diseases of the circulatory system	0.779	0.221	0.000
I70 Atherosclerosis	0.777	0.223	0.000
N04.2 Diffuse membranous glomerulonephritis	0.776	0.224	0.000
M89.5 Osteolysis	0.776	0.224	0.000
E50-E64 Other nutritional deficiencies	0.775	0.225	0.000
L10-L14 Bullous disorders	0.774	0.226	0.000
Q76 Congenital malformations of spine and bony thorax	0.774	0.226	0.000
N13.6 Pyonephrosis	0.772	0.228	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.772	0.228	0.000
E10.0 With coma	0.771	0.229	0.000
C18.9 Colon, unspecified	0.769	0.231	0.000
C02.9 Tongue, unspecified	0.767	0.233	0.000
C18.6 Descending colon	0.766	0.234	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.765	0.235	0.000
M17 Gonarthrosis [arthrosis of knee]	0.765	0.235	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.765	0.235	0.000
Q65 Congenital deformities of hip	0.763	0.237	0.000
E14.1 With ketoacidosis	0.763	0.237	0.000
E10.7 With multiple complications	0.761	0.239	0.000
G30-G32 Other degenerative diseases of the nervous system	0.759	0.241	0.000
D68 Other coagulation defects	0.756	0.244	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.755	0.245	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.753	0.247	0.000
D80 Immunodeficiency with predominantly antibody defects	0.752	0.248	0.000
L94 Other localised connective tissue disorders	0.752	0.248	0.000
D86.8 Sarcoidosis of other and combined sites	0.751	0.249	0.000
L40.3 Pustulosis palmaris et plantaris	0.750	0.250	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.748	0.252	0.000
L50-L54 Urticaria and erythema	0.747	0.253	0.000
M24.1 Other articular cartilage disorders	0.747	0.253	0.000
M17.1 Other primary gonarthrosis	0.745	0.255	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.744	0.256	0.000
A15-A19 Tuberculosis	0.744	0.256	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.742	0.258	0.000
E40-E46 Malnutrition	0.741	0.259	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.741	0.259	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.740	0.260	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.739	0.261	0.000
Q05 Spina bifida	0.736	0.264	0.000
M32 Systemic lupus erythematosus	0.736	0.264	0.000
N13.4 Hydroureter	0.736	0.264	0.000
E06 Thyroiditis	0.735	0.265	0.000
L42 Pityriasis rosea	0.734	0.266	0.000
K50.0 Crohn's disease of small intestine	0.000	0.269	0.731
I70.0 Atherosclerosis of aorta	0.729	0.271	0.000
E14.8 With unspecified complications	0.727	0.273	0.000
N04.1 Focal and segmental glomerular lesions	0.727	0.273	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.727	0.273	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.726	0.274	0.000
E14.2 Withrenal complications	0.725	0.275	0.000
B44 Aspergillosis	0.724	0.276	0.000
M31.6 Other giant cell arteritis	0.721	0.279	0.000
N25 Disorders resulting from impaired renal tubular function	0.720	0.280	0.000
M86.6 Other chronic osteomyelitis	0.720	0.280	0.000
M00-M03 Infectious arthropathies	0.719	0.281	0.000
C34 Malignant neoplasm of bronchus and lung	0.718	0.282	0.000
E05.8 Other thyrotoxicosis	0.717	0.282	0.000
M91-M94 Chondropathies	0.717	0.283	0.000
L93 Lupus erythematosus	0.717	0.283	0.000
M89.0 Algoneurodystrophy	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
C18.4 Transverse colon	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.717	0.283	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.717	0.283	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.716	0.284	0.000
L44 Other papulosquamous disorders	0.715	0.285	0.000
L41 Parapsoriasis	0.715	0.285	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.715	0.285	0.000
M70-M79 Other soft tissue disorders	0.714	0.286	0.000
K90.9 Intestinal malabsorption, unspecified	0.714	0.286	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.713	0.287	0.000
E15 Nondiabetic hypoglycaemic coma	0.711	0.289	0.000
C04 Malignant neoplasm of floor of mouth	0.711	0.289	0.000
M11.2 Other chondrocalcinosis	0.711	0.289	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.711	0.289	0.000
E14.6 With other specified complications	0.710	0.290	0.000
M35.7 Hypermobility syndrome	0.710	0.290	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.710	0.290	0.000
N06 Isolated proteinuria with specified morphological lesion	0.710	0.290	0.000
N01 Rapidly progressive nephritic syndrome	0.710	0.290	0.000
N00 Acute nephritic syndrome	0.710	0.290	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.708	0.291	0.000
M08 Juvenile arthritis	0.708	0.291	0.000
M25.4 Effusion of joint	0.708	0.292	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.708	0.292	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.707	0.293	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.707	0.293	0.000
E16.4 Abnormal secretion of gastrin	0.707	0.293	0.000
E16.3 Increased secretion of glucagon	0.707	0.293	0.000
M25.9 Joint disorder, unspecified	0.707	0.293	0.000
M07.6 Other enteropathic arthropathies	0.706	0.294	0.000
M07.5 Arthropathy in ulcerative colitis	0.706	0.294	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.706	0.294	0.000
M07.2 Psoriatic spondylitis	0.706	0.294	0.000
M07.1 Arthritis mutilans	0.706	0.294	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.706	0.294	0.000
E11.0 With coma	0.705	0.295	0.000
M10.0 Idiopathic gout	0.705	0.295	0.000
M07.38 Other psoriatic arthropathies (Other)	0.705	0.295	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.705	0.295	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.705	0.295	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.705	0.295	0.000
N02 Recurrent and persistent haematuria	0.704	0.296	0.000
M17.9 Gonarthrosis, unspecified	0.704	0.296	0.000
M14 Arthropathies in other diseases classified elsewhere	0.703	0.297	0.000
C18.1 Appendix	0.703	0.297	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.702	0.298	0.000
N05.2 Diffuse membranous glomerulonephritis	0.702	0.298	0.000
N08.8 Glomerular disorders in other diseases classified elsewhere	0.701	0.298	0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.701	0.298	0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.701	0.298	0.000
N08.1 Glomerular disorders in neoplastic diseases	0.701	0.298	0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.701	0.298	0.000
N05.1 Focal and segmental glomerular lesions	0.701	0.299	0.000
I77 Other disorders of arteries and arterioles	0.701	0.299	0.000
N15 Other renal tubulo-interstitial diseases	0.700	0.299	0.000
D82 Immunodeficiency associated with other major defects	0.699	0.301	0.000
D81 Combined immunodeficiencies	0.699	0.301	0.000
M89.3 Hypertrophy of bone	0.699	0.301	0.000
Q78 Other osteochondrodysplasias	0.698	0.302	0.000
E07.8 Other specified disorders of thyroid	0.697	0.303	0.000
M62.88 Other specified disorders of muscle (Other)	0.697	0.303	0.000
M34 Systemic sclerosis	0.697	0.303	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.696	0.304	0.000
D86.3 Sarcoidosis of skin	0.695	0.305	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.694	0.306	0.000
A20-A28 Certain zoonotic bacterial diseases	0.693	0.307	0.000
K50.8 Other Crohn's disease	0.001	0.307	0.692
Q50-Q56 Congenital malformations of genital organs	0.692	0.308	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.692	0.308	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.692	0.308	0.000
D84 Other immunodeficiencies	0.691	0.309	0.000
E14.7 With multiple complications	0.690	0.310	0.000
E14.0 With coma	0.690	0.310	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.311	0.688
Q35-Q37 Cleft lip and cleft palate	0.688	0.312	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.688	0.312	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.688	0.312	0.000
D68.8 Other specified coagulation defects	0.687	0.313	0.000
N04.0 Minor glomerular abnormality	0.686	0.314	0.000
G31.8 Other specified degenerative diseases of nervous system	0.685	0.315	0.000
M90 Osteopathies in diseases classified elsewhere	0.684	0.316	0.000
M62.0 Diastasis of muscle	0.684	0.316	0.000
B37.2 Candidiasis of skin and nail	0.683	0.317	0.000
N04.8 Other	0.681	0.319	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.681	0.319	0.000
N04.6 Dense deposit disease	0.681	0.319	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.681	0.319	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.681	0.319	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.681	0.319	0.000
G70-G73 Diseases of myoneural junction and muscle	0.681	0.319	0.000
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.681	0.319	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.680	0.320	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.680	0.320	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.321	0.679
M86.9 Osteomyelitis, unspecified	0.679	0.321	0.000
L81 Other disorders of pigmentation	0.676	0.324	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.676	0.324	0.000
Q65.8 Other congenital deformities of hip	0.676	0.324	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.675	0.325	0.000
M61 Calcification and ossification of muscle	0.675	0.325	0.000
Q03 Congenital hydrocephalus	0.675	0.325	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.674	0.326	0.000
M21.8 Other specified acquired deformities of limbs	0.674	0.326	0.000
L80 Vitiligo	0.674	0.326	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.674	0.326	0.000
M72 Fibroblastic disorders	0.673	0.327	0.000
B37.3 Candidiasis of vulva and vagina	0.673	0.327	0.000
M65-M68 Disorders of synovium and tendon	0.672	0.328	0.000
K90-K93 Other diseases of the digestive system	0.671	0.328	0.000
Q66 Congenital deformities of feet	0.670	0.330	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.670	0.330	0.000
M88 Paget's disease of bone [osteitis deformans]	0.669	0.331	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.667	0.333	0.000
Q07 Other congenital malformations of nervous system	0.667	0.333	0.000
D61.9 Aplastic anaemia, unspecified	0.667	0.333	0.000
C03 Malignant neoplasm of gum	0.666	0.334	0.000
Q74 Other congenital malformations of limb(s)	0.666	0.334	0.000
Q60-Q64 Congenital malformations of the urinary system	0.666	0.334	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.666	0.334	0.000
E16.1 Other hypoglycaemia	0.666	0.334	0.000
L92.0 Granuloma annulare	0.665	0.335	0.000
M24.2 Disorder of ligament	0.663	0.337	0.000
L89 Decubitus ulcer	0.663	0.337	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.663	0.337	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.662	0.337	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.661	0.339	0.000
N11.1 Chronic obstructive pyelonephritis	0.661	0.339	0.000
E14.4 With neurological complications	0.658	0.342	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.658	0.342	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.658	0.342	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.657	0.343	0.000
E61 Deficiency of other nutrient elements	0.657	0.343	0.000
B37.7 Candidal septicaemia	0.656	0.344	0.000
Q05.9 Spina bifida, unspecified	0.656	0.344	0.000
D68.0 Von Willebrand's disease	0.656	0.344	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.655	0.345	0.000
L95 Vasculitis limited to skin, not elsewhere classified	0.653	0.347	0.000
D86.1 Sarcoidosis of lymph nodes	0.653	0.347	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.652	0.348	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.651	0.349	0.000
M62.9 Disorder of muscle, unspecified	0.650	0.349	0.000
M62.4 Contracture of muscle	0.650	0.349	0.000
M62.3 Immobility syndrome (paraplegic)	0.650	0.349	0.000
M62.2 Ischaemic infarction of muscle	0.650	0.349	0.000
C34.3 Lower lobe, bronchus or lung	0.650	0.350	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.649	0.350	0.000
B36 Other superficial mycoses	0.648	0.352	0.000
Chapter XI Diseases of the digestive system	0.648	0.352	0.000
D50-D53 Nutritional anaemias	0.648	0.352	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.647	0.353	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.647	0.353	0.000
E10.8 With unspecified complications	0.647	0.353	0.000
C34.2 Middle lobe, bronchus or lung	0.646	0.354	0.000
A65-A69 Other spirochaetal diseases	0.645	0.354	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.643	0.357	0.000
Q04 Other congenital malformations of brain	0.641	0.359	0.000
D83.9 Common variable immunodeficiency, unspecified	0.641	0.359	0.000
B49 Unspecified mycosis	0.641	0.359	0.000
M60 Myositis	0.639	0.360	0.000
G31.0 Circumscribed brain atrophy	0.639	0.361	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.639	0.361	0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.637	0.363	0.000
M25.46 Effusion of joint (Lower leg)	0.636	0.364	0.000
L83 Acanthosis nigricans	0.636	0.364	0.000
K90.8 Other intestinal malabsorption	0.635	0.365	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.635	0.365	0.000
Q75 Other congenital malformations of skull and face bones	0.635	0.365	0.000
Q73 Reduction defects of unspecified limb	0.635	0.365	0.000
Q72 Reduction defects of lower limb	0.635	0.365	0.000
Q71 Reduction defects of upper limb	0.635	0.365	0.000
Q70 Syndactyly	0.635	0.365	0.000
Q69 Polydactyly	0.635	0.365	0.000
Q68 Other congenital musculoskeletal deformities	0.635	0.365	0.000
C13 Malignant neoplasm of hypopharynx	0.635	0.365	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.634	0.366	0.000
D58 Other hereditary haemolytic anaemias	0.634	0.366	0.000
B02 Zoster [herpes zoster]	0.633	0.367	0.000
M12.2 Villonodular synovitis (pigmented)	0.633	0.367	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.632	0.368	0.000
C81 Hodgkin's disease	0.631	0.369	0.000
N05.8 Other	0.630	0.370	0.000
I73.8 Other specified peripheral vascular diseases	0.630	0.370	0.000
E11.8 With unspecified complications	0.630	0.370	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.630	0.370	0.000
E06.9 Thyroiditis, unspecified	0.629	0.371	0.000
Q40 Other congenital malformations of upper alimentary tract	0.629	0.371	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.628	0.372	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.628	0.372	0.000
M35.5 Multifocal fibrosclerosis	0.628	0.372	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.628	0.372	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.628	0.372	0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.627	0.373	0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically	0.627	0.373	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.626	0.374	0.000
C10 Malignant neoplasm of oropharynx	0.626	0.374	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.625	0.375	0.000
A75-A79 Rickettsioses	0.625	0.375	0.000
A70-A74 Other diseases caused by chlamydiae	0.625	0.375	0.000
E10.5 With peripheral circulatory complications	0.625	0.375	0.000
C84.5 Other and unspecified T-cell lymphomas	0.625	0.375	0.000
L40.8 Other psoriasis	0.625	0.375	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.624	0.376	0.000
B48 Other mycoses, not elsewhere classified	0.624	0.376	0.000
B47 Mycetoma	0.624	0.376	0.000
B46 Zygomycosis	0.624	0.376	0.000
B45 Cryptococcosis	0.624	0.376	0.000
B43 Chromomycosis and phaeomycotic abscess	0.624	0.376	0.000
B42 Sporotrichosis	0.624	0.376	0.000
B41 Paracoccidioidomycosis	0.624	0.376	0.000
B40 Blastomycosis	0.624	0.376	0.000
B39 Histoplasmosis	0.624	0.376	0.000
B38 Coccidioidomycosis	0.624	0.376	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.624	0.376	0.000
K75 Other inflammatory liver diseases	0.623	0.377	0.000
M86.8 Other osteomyelitis	0.623	0.377	0.000
M33 Dermatopolymyositis	0.623	0.377	0.000
B37.6 Candidal endocarditis	0.622	0.377	0.000
B37.5 Candidal meningitis	0.622	0.377	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.622	0.378	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.622	0.378	0.000
K70-K77 Diseases of liver	0.622	0.378	0.000
M11.8 Other specified crystal arthropathies	0.621	0.378	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.621	0.379	0.000
E13.3 With ophthalmic complications	0.621	0.379	0.000
M17.5 Other secondary gonarthrosis	0.620	0.380	0.000
B37.4 Candidiasis of other urogenital sites	0.619	0.381	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.619	0.381	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.619	0.381	0.000
N05.6 Dense deposit disease	0.619	0.381	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.619	0.381	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.619	0.381	0.000
N05.0 Minor glomerular abnormality	0.619	0.381	0.000
M25.3 Other instability of joint	0.618	0.382	0.000
I74.8 Embolism and thrombosis of other arteries	0.618	0.382	0.000
Q76.0 Spina bifida occulta	0.618	0.382	0.000
K75.4 Autoimmune hepatitis	0.617	0.383	0.000
M62.6 Muscle strain	0.617	0.383	0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.617	0.383	0.000
L87 Transepidermal elimination disorders	0.617	0.383	0.000
L86 Keratoderma in diseases classified elsewhere	0.617	0.383	0.000
D64.4 Congenital dyserythropoietic anaemia	0.616	0.384	0.000
D64.3 Other sideroblastic anaemias	0.616	0.384	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.616	0.384	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.616	0.384	0.000
D64.0 Hereditary sideroblastic anaemia	0.616	0.384	0.000
M89.6 Osteopathy after poliomyelitis	0.616	0.384	0.000
M89.2 Other disorders of bone development and growth	0.616	0.384	0.000
M89.1 Epiphyseal arrest	0.616	0.384	0.000
M24.7 Protrusio acetabuli	0.615	0.385	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.614	0.386	0.000
M25.7 Osteophyte	0.614	0.386	0.000
D73 Diseases of spleen	0.614	0.386	0.000
L13 Other bullous disorders	0.613	0.387	0.000
L88 Pyoderma gangrenosum	0.613	0.387	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.613	0.387	0.000
K90.3 Pancreatic steatorrhoea	0.613	0.387	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.613	0.387	0.000
K90.1 Tropical sprue	0.613	0.387	0.000
L81.9 Disorder of pigmentation, unspecified	0.613	0.387	0.000
L94.2 Calcinosis cutis	0.612	0.388	0.000
M31.7 Microscopic polyangiitis	0.612	0.388	0.000
D72 Other disorders of white blood cells	0.611	0.389	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.609	0.390	0.000
B44.9 Aspergillosis, unspecified	0.609	0.391	0.000
C34.0 Main bronchus	0.609	0.391	0.000
Q06 Other congenital malformations of spinal cord	0.609	0.391	0.000
Q01 Encephalocele	0.609	0.391	0.000
Q00 Anencephaly and similar malformations	0.609	0.391	0.000
Q02 Microcephaly	0.609	0.391	0.000
E13.9 Without complications	0.608	0.392	0.000
I77.6 Arteritis, unspecified	0.608	0.392	0.000
D59 Acquired haemolytic anaemia	0.608	0.392	0.000
M25.2 Flail joint	0.607	0.392	0.000
M25.1 Fistula of joint	0.607	0.392	0.000
C11 Malignant neoplasm of nasopharynx	0.606	0.394	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.605	0.395	0.000
M11.9 Crystal arthropathy, unspecified	0.605	0.395	0.000
D68.9 Coagulation defect, unspecified	0.605	0.395	0.000
L94.0 Localised scleroderma [morphea]	0.604	0.396	0.000
D61.1 Drug-induced aplastic anaemia	0.604	0.396	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.604	0.396	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.603	0.397	0.000
C04.0 Anterior floor of mouth	0.603	0.397	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.602	0.398	0.000
D61.0 Constitutional aplastic anaemia	0.602	0.398	0.000
M18 Arthrosis of first carpometacarpal joint	0.601	0.399	0.000
M86.5 Other chronic haematogenous osteomyelitis	0.601	0.399	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.601	0.399	0.000
M86.3 Chronic multifocal osteomyelitis	0.601	0.399	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations