TreeWAS – Variant ID: rs3002142

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I25.8 Other forms of chronic ischaemic heart disease	1.000	0.000	0.000
I25.2 Old myocardial infarction	0.999	0.001	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.997	0.003	0.000
I20-I25 Ischaemic heart diseases	0.968	0.032	0.000
I22 Subsequent myocardial infarction	0.965	0.035	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.958	0.042	0.000
I25.1 Atherosclerotic heart disease	0.953	0.047	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.852	0.148	0.000
I21 Acute myocardial infarction	0.839	0.161	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.781	0.219	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.762	0.238	0.000
I25.5 Ischaemic cardiomyopathy	0.750	0.250	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.733	0.267	0.000
I25.6 Silent myocardial ischaemia	0.701	0.298	0.000
I23 Certain current complications following acute myocardial infarction	0.688	0.312	0.000
I22.8 Subsequent myocardial infarction of other sites	0.675	0.325	0.000
I21.9 Acute myocardial infarction, unspecified	0.657	0.343	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.628	0.372	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.601	0.399	0.000
I20 Angina pectoris	0.578	0.422	0.000
I25.4 Coronary artery aneurysm	0.551	0.449	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.548	0.452	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.532	0.468	0.000
I23.8 Other current complications following acute myocardial infarction	0.497	0.503	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.493	0.506	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.493	0.506	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.493	0.506	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.493	0.506	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.493	0.506	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.493	0.506	0.000
I21.4 Acute subendocardial myocardial infarction	0.484	0.516	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.483	0.516	0.000
I20.9 Angina pectoris, unspecified	0.448	0.552	0.000
I20.0 Unstable angina	0.405	0.595	0.000
I25.3 Aneurysm of heart	0.394	0.605	0.001
I20.8 Other forms of angina pectoris	0.360	0.640	0.000
I20.1 Angina pectoris with documented spasm	0.329	0.671	0.000
I24 Other acute ischaemic heart diseases	0.204	0.796	0.000
I24.1 Dressler's syndrome	0.153	0.846	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.115	0.885	0.000
R07.4 Chest pain, unspecified	0.096	0.904	0.000
I24.8 Other forms of acute ischaemic heart disease	0.059	0.941	0.000
D12.6 Colon, unspecified	0.000	0.954	0.046
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.000	0.955	0.045
I24.9 Acute ischaemic heart disease, unspecified	0.044	0.956	0.001
D12.3 Transverse colon	0.000	0.959	0.041
D12.2 Ascending colon	0.000	0.960	0.040
D12.7 Rectosigmoid junction	0.000	0.960	0.040
D12.0 Caecum	0.000	0.961	0.039
D12.1 Appendix	0.000	0.962	0.038
D12.4 Descending colon	0.000	0.964	0.036
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.965	0.035
D12.9 Anus and anal canal	0.000	0.970	0.030
D12.5 Sigmoid colon	0.000	0.970	0.030
D12.8 Rectum	0.000	0.971	0.029
I77.1 Stricture of artery	0.023	0.977	0.000
M81.9 Osteoporosis, unspecified	0.000	0.978	0.022
I77 Other disorders of arteries and arterioles	0.021	0.979	0.000
M81.98 Osteoporosis, unspecified (Other)	0.000	0.980	0.020
I77.9 Disorder of arteries and arterioles, unspecified	0.018	0.982	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.982	0.018
I77.8 Other specified disorders of arteries and arterioles	0.018	0.982	0.000
I77.2 Rupture of artery	0.017	0.982	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.983	0.017
I77.0 Arteriovenous fistula, acquired	0.017	0.983	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.984	0.016
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.984	0.016
I77.3 Arterial fibromuscular dysplasia	0.016	0.984	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.985	0.015
I77.5 Necrosis of artery	0.015	0.985	0.000
I77.4 Coeliac artery compression syndrome	0.015	0.985	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.985	0.015
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.986	0.014
I77.6 Arteritis, unspecified	0.014	0.986	0.000
R07 Pain in throat and chest	0.013	0.987	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.987	0.012
I70-I79 Diseases of arteries, arterioles and capillaries	0.011	0.989	0.000
F10.2 Dependence syndrome	0.011	0.989	0.000
M81 Osteoporosis without pathological fracture	0.000	0.989	0.011
R07.0 Pain in throat	0.010	0.990	0.000
Y40 Systemic antibiotics	0.010	0.990	0.000
K86.1 Other chronic pancreatitis	0.010	0.990	0.000
N84.1 Polyp of cervix uteri	0.000	0.990	0.010
R07.2 Precordial pain	0.010	0.990	0.000
I74 Arterial embolism and thrombosis	0.009	0.991	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.009	0.991	0.000
Y40.0 Penicillins	0.009	0.991	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.009	0.991	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.009	0.991	0.000
Y40.8 Other systemic antibiotics	0.009	0.991	0.000
M81.0 Postmenopausal osteoporosis	0.000	0.991	0.009
Y44.2 Anticoagulants	0.009	0.991	0.000
Y44 Agents primarily affecting blood constituents	0.009	0.991	0.000
L40.9 Psoriasis, unspecified	0.009	0.991	0.000
Y40.7 Antifungal antibiotics, systemically used	0.008	0.991	0.000
S00.9 Superficial injury of head, part unspecified	0.000	0.991	0.009
I74.5 Embolism and thrombosis of iliac artery	0.008	0.992	0.000
M81.2 Osteoporosis of disuse	0.000	0.992	0.008
Y40.4 Tetracyclines	0.008	0.992	0.000
I72 Other aneurysm	0.008	0.992	0.000
K86 Other diseases of pancreas	0.008	0.992	0.000
Y45.1 Salicylates	0.008	0.992	0.000
M81.8 Other osteoporosis	0.000	0.992	0.008
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.992	0.008
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.008	0.992	0.000
S00.1 Contusion of eyelid and periocular area	0.000	0.992	0.008
Y40.3 Macrolides	0.008	0.992	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.008	0.992	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.008	0.992	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.008	0.992	0.000
M81.6 Localised osteoporosis [Lequesne]	0.000	0.992	0.008
M81.5 Idiopathic osteoporosis	0.000	0.992	0.008
Y46 Antiepileptics and anti-Parkinsonism drugs	0.008	0.992	0.000
I72.8 Aneurysm of other specified arteries	0.008	0.992	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.008	0.992	0.000
K86.3 Pseudocyst of pancreas	0.008	0.992	0.000
Y40.9 Systemic antibiotic, unspecified	0.008	0.992	0.000
S00 Superficial injury of head	0.000	0.992	0.008
M81.1 Postoophorectomy osteoporosis	0.000	0.992	0.007
Y40.2 Chloramphenicol group	0.007	0.992	0.000
Chapter IX Diseases of the circulatory system	0.008	0.992	0.000
I74.8 Embolism and thrombosis of other arteries	0.007	0.992	0.000
Y57 Other and unspecified drugs and medicaments	0.008	0.992	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.007	0.993	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.007	0.993	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.000	0.993	0.007
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.007	0.993	0.000
K86.8 Other specified diseases of pancreas	0.007	0.993	0.000
I73 Other peripheral vascular diseases	0.007	0.993	0.000
Y40.5 Aminoglycosides	0.007	0.993	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.007	0.993	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.000	0.993	0.007
Y43 Primarily systemic agents	0.007	0.993	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.000	0.993	0.007
Y40.6 Rifamycins	0.007	0.993	0.000
Y52 Agents primarily affecting the cardiovascular system	0.007	0.993	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.007	0.993	0.000
Y57.8 Other drugs and medicaments	0.007	0.993	0.000
I70 Atherosclerosis	0.007	0.993	0.000
Y54.4 Loop [high-ceiling] diuretics	0.007	0.993	0.000
I79.1 Aortitis in diseases classified elsewhere	0.007	0.993	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.007	0.993	0.000
Y45.8 Other analgesics and antipyretics	0.007	0.993	0.000
I72.0 Aneurysm of carotid artery	0.007	0.993	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.007	0.993	0.000
Y46.2 Hydantoin derivatives	0.007	0.993	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.007	0.993	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.007	0.993	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.000	0.993	0.007
K86.9 Disease of pancreas, unspecified	0.007	0.993	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.007	0.993	0.000
Y58 Bacterial vaccines	0.007	0.993	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.006	0.993	0.000
Y46.7 Anti-Parkinsonism drugs	0.007	0.993	0.000
R07.1 Chest pain on breathing	0.006	0.993	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.000	0.993	0.006
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.000	0.993	0.006
M81.06 Postmenopausal osteoporosis (Lower leg)	0.000	0.993	0.006
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.000	0.993	0.006
M81.04 Postmenopausal osteoporosis (Hand)	0.000	0.993	0.006
M81.03 Postmenopausal osteoporosis (Forearm)	0.000	0.993	0.006
M81.02 Postmenopausal osteoporosis (Upper arm)	0.000	0.993	0.006
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.000	0.993	0.006
Q21.1 Atrial septal defect	0.000	0.993	0.007
Y44.5 Thrombolytic drugs	0.006	0.993	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.006	0.993	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.006	0.993	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.006	0.993	0.000
Y44.7 Plasma substitutes	0.006	0.993	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.006	0.993	0.000
Y44.6 Natural blood and blood products	0.006	0.994	0.000
S00.8 Superficial injury of other parts of head	0.000	0.994	0.006
Y45.5 4-Aminophenol derivatives	0.006	0.994	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.006	0.994	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.006	0.994	0.000
Y52.1 Calcium-channel blockers	0.006	0.994	0.000
I72.9 Aneurysm of unspecified site	0.006	0.994	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.000	0.994	0.006
M81.29 Osteoporosis of disuse (Site unspecified)	0.000	0.994	0.006
M81.28 Osteoporosis of disuse (Other)	0.000	0.994	0.006
M81.27 Osteoporosis of disuse (Ankle and foot)	0.000	0.994	0.006
M81.26 Osteoporosis of disuse (Lower leg)	0.000	0.994	0.006
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.000	0.994	0.006
M81.24 Osteoporosis of disuse (Hand)	0.000	0.994	0.006
M81.23 Osteoporosis of disuse (Forearm)	0.000	0.994	0.006
M81.22 Osteoporosis of disuse (Upper arm)	0.000	0.994	0.006
M81.21 Osteoporosis of disuse (Shoulder region)	0.000	0.994	0.006
I73.8 Other specified peripheral vascular diseases	0.006	0.994	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.006	0.994	0.000
M81.80 Other osteoporosis (Multiple sites)	0.000	0.994	0.006
I72.6 Aneurysm and dissection of vertebral artery	0.006	0.994	0.000
I72.4 Aneurysm of artery of lower extremity	0.006	0.994	0.000
M81.89 Other osteoporosis (Site unspecified)	0.000	0.994	0.006
I74.9 Embolism and thrombosis of unspecified artery	0.006	0.994	0.000
Y46.5 Valproic acid	0.006	0.994	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.006	0.994	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.000	0.994	0.006
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.000	0.994	0.006
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.000	0.994	0.006
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.000	0.994	0.006
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.000	0.994	0.006
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.000	0.994	0.006
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.000	0.994	0.006
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.000	0.994	0.006
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.000	0.994	0.006
M81.88 Other osteoporosis (Other)	0.000	0.994	0.006
M81.87 Other osteoporosis (Ankle and foot)	0.000	0.994	0.006
M81.86 Other osteoporosis (Lower leg)	0.000	0.994	0.006
M81.85 Other osteoporosis (Pelvic region and thigh)	0.000	0.994	0.006
M81.84 Other osteoporosis (Hand)	0.000	0.994	0.006
M81.83 Other osteoporosis (Forearm)	0.000	0.994	0.006
M81.82 Other osteoporosis (Upper arm)	0.000	0.994	0.006
M81.81 Other osteoporosis (Shoulder region)	0.000	0.994	0.006
S00.4 Superficial injury of ear	0.000	0.994	0.006
I72.5 Aneurysm and dissection of other precerebral arteries	0.006	0.994	0.000
Y54.0 Mineralocorticoids	0.006	0.994	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.006	0.994	0.000
I00-I02 Acute rheumatic fever	0.006	0.994	0.000
Y59 Other and unspecified vaccines and biological substances	0.006	0.994	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.006	0.994	0.000
M81.4 Drug-induced osteoporosis	0.000	0.994	0.006
F10.6 Amnesic syndrome	0.006	0.994	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.000	0.994	0.006
M81.58 Idiopathic osteoporosis (Other)	0.000	0.994	0.006
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.000	0.994	0.006
M81.56 Idiopathic osteoporosis (Lower leg)	0.000	0.994	0.006
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.000	0.994	0.006
M81.54 Idiopathic osteoporosis (Hand)	0.000	0.994	0.006
M81.53 Idiopathic osteoporosis (Forearm)	0.000	0.994	0.006
M81.52 Idiopathic osteoporosis (Upper arm)	0.000	0.994	0.006
M81.51 Idiopathic osteoporosis (Shoulder region)	0.000	0.994	0.006
M81.50 Idiopathic osteoporosis (Multiple sites)	0.000	0.994	0.006
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.000	0.994	0.006
M81.68 Localized osteoporosis [Lequesne] (Other)	0.000	0.994	0.006
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.000	0.994	0.006
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.000	0.994	0.006
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.000	0.994	0.006
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.000	0.994	0.006
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.000	0.994	0.006
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.000	0.994	0.006
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.000	0.994	0.006
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.000	0.994	0.006
F10.0 Acute intoxication	0.006	0.994	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.006	0.994	0.000
Y46.8 Antispasticity drugs	0.006	0.994	0.000
Y46.3 Deoxybarbiturates	0.006	0.994	0.000
Y46.1 Oxazolidinediones	0.006	0.994	0.000
Y46.0 Succinimides	0.006	0.994	0.000
Y54.9 Mineral salts, not elsewhere classified	0.006	0.994	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.006	0.994	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.006	0.994	0.000
Y57.9 Drug or medicament, unspecified	0.006	0.994	0.000
Y46.6 Other and unspecified antiepileptics	0.006	0.994	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.006	0.994	0.000
Y43.2 Antineoplastic natural products	0.006	0.994	0.000
Y54.7 Agents affecting calcification	0.006	0.994	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.000	0.994	0.005
M81.18 Postoophorectomy osteoporosis (Other)	0.000	0.994	0.005
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.000	0.994	0.005
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.000	0.994	0.005
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.000	0.994	0.005
M81.14 Postoophorectomy osteoporosis (Hand)	0.000	0.994	0.005
M81.13 Postoophorectomy osteoporosis (Forearm)	0.000	0.994	0.005
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.000	0.994	0.005
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.000	0.994	0.005
Y43.4 Immunosuppressive agents	0.006	0.994	0.000
Y54.8 Agents affecting uric acid metabolism	0.006	0.994	0.000
Y55.4 Expectorants	0.006	0.994	0.000
Y57.7 Vitamins, not elsewhere classified	0.006	0.994	0.000
Y57.4 Pharmaceutical excipients	0.006	0.994	0.000
Y57.3 Alcohol deterrents	0.006	0.994	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.006	0.994	0.000
Y57.1 Lipotropic drugs	0.006	0.994	0.000
Y57.0 Appetite depressants [anorectics]	0.006	0.994	0.000
I72.1 Aneurysm of artery of upper extremity	0.005	0.994	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.006	0.994	0.000
Y54.3 Benzothiadiazine derivatives	0.006	0.994	0.000
Y41.5 Antiviral drugs	0.006	0.994	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.005	0.994	0.000
Y45.2 Propionic acid derivatives	0.006	0.994	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.006	0.994	0.000
I78 Diseases of capillaries	0.006	0.994	0.000
Y57.6 Other diagnostic agents	0.005	0.994	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.005	0.994	0.000
Y55.5 Anticommon cold drugs	0.005	0.994	0.000
Y55.3 Antitussives	0.005	0.994	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.005	0.994	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.000	0.994	0.005
I70.8 Atherosclerosis of other arteries	0.005	0.994	0.000
Y43.0 Antiallergic and antiemetic drugs	0.005	0.994	0.000
F10.5 Psychotic disorder	0.005	0.995	0.000
Y46.4 Iminostilbenes	0.005	0.995	0.000
Y45.4 Antirheumatics	0.005	0.995	0.000
Y55.0 Oxytocic drugs	0.005	0.995	0.000
Y52.7 Peripheral vasodilators	0.005	0.995	0.000
Y43.9 Primarily systemic agent, unspecified	0.005	0.995	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.005	0.995	0.000
Y43.6 Enzymes, not elsewhere classified	0.005	0.995	0.000
Y43.5 Acidifying and alkalising agents	0.005	0.995	0.000
Y43.3 Other antineoplastic drugs	0.005	0.995	0.000
S00.7 Multiple superficial injuries of head	0.000	0.995	0.005
Y47.1 Benzodiazepines	0.005	0.995	0.000
F10.7 Residual and late-onset psychotic disorder	0.005	0.995	0.000
Y53.2 Stimulant laxatives	0.005	0.995	0.000
Y50.9 Central nervous system stimulant, unspecified	0.005	0.995	0.000
Y50.8 Other central nervous system stimulants	0.005	0.995	0.000
Y50.1 Opioid receptor antagonists	0.005	0.995	0.000
Y50.0 Analeptics	0.005	0.995	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.005	0.995	0.000
Y53.4 Other laxatives	0.005	0.995	0.000
Y53.6 Antidiarrhoeal drugs	0.005	0.995	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.005	0.995	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.005	0.995	0.000
Y54.5 Other diuretics	0.005	0.995	0.000
S00.5 Superficial injury of lip and oral cavity	0.000	0.995	0.005
S00.3 Superficial injury of nose	0.000	0.995	0.005
I73.9 Peripheral vascular disease, unspecified	0.005	0.995	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.005	0.995	0.000
F10.8 Other mental and behavioural disorders	0.005	0.995	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.005	0.995	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.005	0.995	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.005	0.995	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.005	0.995	0.000
Y47.4 Bromine compounds	0.005	0.995	0.000
Y47.3 Paraldehyde	0.005	0.995	0.000
Y47.2 Chloral derivatives	0.005	0.995	0.000
Y47.0 Barbiturates, not elsewhere classified	0.005	0.995	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.005	0.995	0.000
Y53.7 Emetics	0.005	0.995	0.000
Y53.5 Digestants	0.005	0.995	0.000
Y53.0 Histamine H2-receptor antagonists	0.005	0.995	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.005	0.995	0.000
I70.1 Atherosclerosis of renal artery	0.005	0.995	0.000
Y41.0 Sulphonamides	0.005	0.995	0.000
Y58.9 Other and unspecified bacterial vaccines	0.005	0.995	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.005	0.995	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.005	0.995	0.000
Y58.5 Diphtheria vaccine	0.005	0.995	0.000
Y58.4 Tetanus vaccine	0.005	0.995	0.000
Y58.3 Plague vaccine	0.005	0.995	0.000
Y58.2 Cholera vaccine	0.005	0.995	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.005	0.995	0.000
I70.9 Generalised and unspecified atherosclerosis	0.005	0.995	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.005	0.995	0.000
Y58.0 BCG vaccine	0.005	0.995	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.005	0.995	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.005	0.995	0.000
F10.9 Unspecified mental and behavioural disorder	0.005	0.995	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.005	0.995	0.000
Y41.4 Anthelminthics	0.005	0.995	0.000
Y41.3 Other antiprotozoal drugs	0.005	0.995	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.005	0.995	0.000
I00 Rheumatic fever without mention of heart involvement	0.005	0.995	0.000
I70.0 Atherosclerosis of aorta	0.005	0.995	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.005	0.995	0.000
Y57.5 X-ray contrast media	0.005	0.995	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.005	0.995	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.005	0.995	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.005	0.995	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.005	0.995	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.005	0.995	0.000
Y51.0 Anticholinesterase agents	0.005	0.995	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.005	0.995	0.000
Y43.1 Antineoplastic antimetabolites	0.005	0.995	0.000
I72.3 Aneurysm of iliac artery	0.005	0.995	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.005	0.995	0.000
Y53.3 Saline and osmotic laxatives	0.004	0.995	0.000
F10.4 Withdrawal state with delirium	0.005	0.995	0.000
I44.2 Atrioventricular block, complete	0.005	0.995	0.000
Y48 Anaesthetics and therapeutic gases	0.004	0.995	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.004	0.995	0.001
Y49.9 Psychotropic drug, unspecified	0.004	0.995	0.000
Y49.7 Psychostimulants with abuse potential	0.004	0.995	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.004	0.995	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.004	0.995	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.004	0.995	0.000
I02 Rheumatic chorea	0.004	0.995	0.000
I01 Rheumatic fever with heart involvement	0.004	0.995	0.000
Y59.9 Vaccine or biological substance, unspecified	0.004	0.995	0.000
Y59.8 Other specified vaccines and biological substances	0.004	0.995	0.000
Y59.2 Protozoal vaccines	0.004	0.995	0.000
Y59.1 Rickettsial vaccines	0.004	0.995	0.000
I72.2 Aneurysm of renal artery	0.004	0.995	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.004	0.995	0.000
M81.48 Drug-induced osteoporosis (Other)	0.000	0.995	0.004
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.000	0.995	0.004
M81.46 Drug-induced osteoporosis (Lower leg)	0.000	0.995	0.004
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.000	0.995	0.004
M81.44 Drug-induced osteoporosis (Hand)	0.000	0.995	0.004
M81.43 Drug-induced osteoporosis (Forearm)	0.000	0.995	0.004
M81.42 Drug-induced osteoporosis (Upper arm)	0.000	0.995	0.004
M81.41 Drug-induced osteoporosis (Shoulder region)	0.000	0.995	0.004
Y49.0 Tricyclic and tetracyclic antidepressants	0.004	0.995	0.000
Y49.2 Other and unspecified antidepressants	0.004	0.995	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.995	0.000
Y41.1 Antimycobacterial drugs	0.004	0.995	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.004	0.996	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
I78.9 Disease of capillaries, unspecified	0.004	0.996	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.004	0.996	0.000
H54.0 Blindness, both eyes	0.000	0.996	0.004
Y49.5 Other antipsychotics and neuroleptics	0.004	0.996	0.000
Y59.0 Viral vaccines	0.004	0.996	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.004	0.996	0.000
Y45.0 Opioids and related analgesics	0.004	0.996	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.004	0.996	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.004	0.996	0.000
Y59.3 Immunoglobulin	0.004	0.996	0.000
B18.2 Chronic viral hepatitis C	0.000	0.996	0.004
I78.8 Other diseases of capillaries	0.004	0.996	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.996	0.004
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.004	0.996	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.004	0.996	0.000
K86.2 Cyst of pancreas	0.004	0.996	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.004	0.996	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.004	0.996	0.000
S00.0 Superficial injury of scalp	0.000	0.996	0.004
Q21 Congenital malformations of cardiac septa	0.000	0.996	0.004
I70.11 Atherosclerosis of renal artery (with gangrene)	0.004	0.996	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.000	0.996	0.004
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.004	0.996	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.004	0.996	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.004	0.996	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.003	0.996	0.000
Y42.2 Antithyroid drugs	0.004	0.996	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.003	0.996	0.000
Y42.7 Androgens and anabolic congeners	0.004	0.996	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.000	0.996	0.004
H54 Blindness and low vision	0.000	0.996	0.004
Y48.5 Therapeutic gases	0.003	0.996	0.000
Y48.1 Parenteral anaesthetics	0.003	0.996	0.000
Y48.0 Inhaled anaesthetics	0.003	0.996	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.003	0.996	0.000
Y56.9 Topical agent, unspecified	0.003	0.996	0.001
Y56.8 Other topical agents	0.003	0.996	0.001
Y56.7 Dental drugs, topically applied	0.003	0.996	0.001
Y56.6 Otorhinolaryngological drugs and preparations	0.003	0.996	0.001
Y56.5 Ophthalmological drugs and preparations	0.003	0.996	0.001
Y56.2 Local astringents and local detergents	0.003	0.996	0.001
Y56.1 Antipruritics	0.003	0.996	0.001
I01.9 Acute rheumatic heart disease, unspecified	0.003	0.996	0.000
I01.8 Other acute rheumatic heart disease	0.003	0.996	0.000
I01.2 Acute rheumatic myocarditis	0.003	0.996	0.000
I01.1 Acute rheumatic endocarditis	0.003	0.996	0.000
I01.0 Acute rheumatic pericarditis	0.003	0.996	0.000
I02.9 Rheumatic chorea without heart involvement	0.003	0.996	0.000
I02.0 Rheumatic chorea with heart involvement	0.003	0.996	0.000
H54.7 Unspecified visual loss	0.000	0.996	0.004
Q21.8 Other congenital malformations of cardiac septa	0.000	0.996	0.003
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.997	0.001
F10.3 Withdrawal state	0.003	0.997	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.003	0.997	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.003	0.997	0.000
Y48.4 Anaesthetic, unspecified	0.003	0.997	0.000
L29.0 Pruritus ani	0.003	0.997	0.000
Y48.2 Other and unspecified general anaesthetics	0.003	0.997	0.000
H54.2 Low vision, both eyes	0.000	0.997	0.003
Y42.4 Oral contraceptives	0.003	0.997	0.000
Y56.3 Emollients, demulcents and protectants	0.003	0.997	0.001
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.997	0.003
H54.6 Unqualified visual loss, one eye	0.000	0.997	0.003
Y42.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
H54.1 Blindness, one eye, low vision, other eye	0.000	0.997	0.003
N03.9 Unspecified	0.000	0.997	0.003
B18 Chronic viral hepatitis	0.000	0.997	0.003
H54.5 Low vision, one eye	0.000	0.997	0.003
Q21.4 Aortopulmonary septal defect	0.000	0.997	0.003
Q21.2 Atrioventricular septal defect	0.000	0.997	0.003
Y42.1 Thyroid hormones and substitutes	0.003	0.997	0.000
A41.1 Septicaemia due to other specified staphylococcus	0.003	0.997	0.000
Q21.3 Tetralogy of Fallot	0.000	0.997	0.003
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.003	0.997	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.000	0.997	0.003
L40 Psoriasis	0.003	0.997	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.000	0.997	0.003
H54.3 Unqualified visual loss, both eyes	0.000	0.997	0.003
H54.9 Unspecified visual impairment (binocular)	0.000	0.997	0.003
E27 Other disorders of adrenal gland	0.003	0.997	0.000
B18.9 Chronic viral hepatitis, unspecified	0.000	0.997	0.003
S91.1 Open wound of toe(s) without damage to nail	0.000	0.997	0.003
K70.9 Alcoholic liver disease, unspecified	0.003	0.997	0.000
Y48.3 Local anaesthetics	0.002	0.997	0.001
A41 Other septicaemia	0.003	0.997	0.000
L84 Corns and callosities	0.000	0.997	0.003
I67.9 Cerebrovascular disease, unspecified	0.003	0.997	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.997	0.001
Q21.0 Ventricular septal defect	0.000	0.997	0.002
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.002	0.997	0.000
Y42.5 Other oestrogens and progestogens	0.003	0.997	0.000
H61.2 Impacted cerumen	0.003	0.997	0.000
L40.8 Other psoriasis	0.002	0.997	0.000
B18.8 Other chronic viral hepatitis	0.000	0.997	0.002
B18.0 Chronic viral hepatitis B with delta-agent	0.000	0.997	0.002
E27.1 Primary adrenocortical insufficiency	0.002	0.997	0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.003	0.997	0.000
N72 Inflammatory disease of cervix uteri	0.003	0.997	0.000
E27.9 Disorder of adrenal gland, unspecified	0.002	0.997	0.000
K14.9 Disease of tongue, unspecified	0.000	0.997	0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations