TreeWAS – Variant ID: rs3020418

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M16.9 Coxarthrosis, unspecified	0.000	0.614	0.386
S82.80 Fractures of other parts of lower leg (closed)	0.369	0.631	0.000
S82.8 Fractures of other parts of lower leg	0.199	0.801	0.000
S82.81 Fractures of other parts of lower leg (open)	0.159	0.841	0.000
S82.86 Maisonneuve's fracture	0.143	0.857	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.034	0.966	0.000
I63 Cerebral infarction	0.033	0.967	0.000
I63.8 Other cerebral infarction	0.033	0.967	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.031	0.969	0.000
S82 Fracture of lower leg, including ankle	0.031	0.969	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.030	0.970	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.026	0.974	0.000
S82.4 Fracture of fibula alone	0.025	0.975	0.000
S82.3 Fracture of lower end of tibia	0.025	0.975	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.024	0.976	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.024	0.976	0.000
S82.5 Fracture of medial malleolus	0.022	0.978	0.000
S82.31 Fracture of lower end of tibia (open)	0.022	0.978	0.000
S82.9 Fracture of lower leg, part unspecified	0.021	0.979	0.000
S82.40 Fracture of fibula alone (closed)	0.021	0.979	0.000
S82.7 Multiple fractures of lower leg	0.021	0.979	0.000
S82.0 Fracture of patella	0.021	0.979	0.000
S82.51 Fracture of medial malleolus (open)	0.019	0.981	0.000
S82.2 Fracture of shaft of tibia	0.019	0.981	0.000
S82.41 Fracture of fibula alone (open)	0.018	0.982	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.018	0.982	0.000
S82.6 Fracture of lateral malleolus	0.016	0.984	0.000
S82.1 Fracture of upper end of tibia	0.016	0.984	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.015	0.985	0.000
S82.71 Multiple fractures of lower leg (open)	0.015	0.985	0.000
S82.30 Fracture of lower end of tibia (closed)	0.014	0.986	0.000
S82.01 Fracture of patella (open)	0.014	0.986	0.000
S82.00 Fracture of patella (closed)	0.014	0.986	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.013	0.986	0.000
S82.70 Multiple fractures of lower leg (closed)	0.013	0.987	0.000
S82.20 Fracture of shaft of tibia (closed)	0.012	0.988	0.000
S82.21 Fracture of shaft of tibia (open)	0.012	0.988	0.000
S82.50 Fracture of medial malleolus (closed)	0.011	0.988	0.000
S82.61 Fracture of lateral malleolus (open)	0.011	0.989	0.000
S82.11 Fracture of upper end of tibia (open)	0.011	0.989	0.000
M16 Coxarthrosis [arthrosis of hip]	0.000	0.989	0.011
M81.99 Osteoporosis, unspecified (Site unspecified)	0.009	0.991	0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.000	0.992	0.008
M16.4 Posttraumatic coxarthrosis, bilateral	0.000	0.992	0.008
M16.5 Other posttraumatic coxarthrosis	0.000	0.992	0.008
M81.9 Osteoporosis, unspecified	0.007	0.993	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.007	0.993	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.007	0.993	0.000
H20.9 Iridocyclitis, unspecified	0.007	0.993	0.000
M16.6 Other secondary coxarthrosis, bilateral	0.000	0.993	0.007
S82.60 Fracture of lateral malleolus (closed)	0.006	0.994	0.000
M16.3 Other dysplastic coxarthrosis	0.000	0.994	0.006
S82.10 Fracture of upper end of tibia (closed)	0.006	0.994	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.994	0.006
H20 Iridocyclitis	0.006	0.994	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.006	0.994	0.000
D37.4 Colon	0.000	0.994	0.006
M81.92 Osteoporosis, unspecified (Upper arm)	0.005	0.994	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.005	0.994	0.000
I63.9 Cerebral infarction, unspecified	0.006	0.994	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.005	0.994	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.005	0.994	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.000	0.994	0.006
M81.94 Osteoporosis, unspecified (Hand)	0.005	0.995	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.995	0.005
M81.96 Osteoporosis, unspecified (Lower leg)	0.005	0.995	0.000
D37.9 Digestive organ, unspecified	0.000	0.995	0.005
D05.9 Carcinoma in situ of breast, unspecified	0.005	0.995	0.000
D37.5 Rectum	0.000	0.995	0.005
Z50.5 Speech therapy	0.005	0.995	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.995	0.005
D37.0 Lip, oral cavity and pharynx	0.000	0.995	0.005
H17.9 Corneal scar and opacity, unspecified	0.005	0.995	0.000
H20.8 Other iridocyclitis	0.005	0.995	0.000
M16.0 Primary coxarthrosis, bilateral	0.000	0.995	0.005
T46.1 Calcium-channel blockers	0.000	0.995	0.005
D37.3 Appendix	0.000	0.995	0.005
D37.2 Small intestine	0.000	0.995	0.005
H20.1 Chronic iridocyclitis	0.005	0.995	0.000
M81 Osteoporosis without pathological fracture	0.005	0.995	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.005	0.995	0.000
H17 Corneal scars and opacities	0.004	0.996	0.000
H20.2 Lens-induced iridocyclitis	0.004	0.996	0.000
H18 Other disorders of cornea	0.004	0.996	0.000
M81.98 Osteoporosis, unspecified (Other)	0.004	0.996	0.000
H18.8 Other specified disorders of cornea	0.004	0.996	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.996	0.004
M81.4 Drug-induced osteoporosis	0.004	0.996	0.000
W25.9 Unspecified place	0.000	0.996	0.004
D37.1 Stomach	0.000	0.996	0.004
H16 Keratitis	0.004	0.996	0.000
H20.0 Acute and subacute iridocyclitis	0.004	0.996	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.996	0.004
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.996	0.004
T46.7 Peripheral vasodilators	0.000	0.996	0.004
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.996	0.004
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.996	0.004
H16.9 Keratitis, unspecified	0.004	0.996	0.000
H16.8 Other keratitis	0.004	0.996	0.000
M16.7 Other secondary coxarthrosis	0.000	0.996	0.004
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.996	0.004
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.996	0.004
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.996	0.004
M81.49 Drug-induced osteoporosis (Site unspecified)	0.004	0.996	0.000
D37.6 Liver, gallbladder and bile ducts	0.000	0.996	0.004
H18.6 Keratoconus	0.004	0.996	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.996	0.004
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.996	0.004
M81.3 Postsurgical malabsorption osteoporosis	0.004	0.996	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.004	0.996	0.000
D34 Benign neoplasm of thyroid gland	0.004	0.996	0.000
M24.02 Loose body in joint (Upper arm)	0.000	0.996	0.004
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.996	0.004
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.996	0.004
T42.1 Iminostilbenes	0.000	0.996	0.004
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.004	0.996	0.000
M81.8 Other osteoporosis	0.003	0.996	0.000
M81.6 Localised osteoporosis [Lequesne]	0.003	0.996	0.000
M81.5 Idiopathic osteoporosis	0.003	0.996	0.000
M81.1 Postoophorectomy osteoporosis	0.003	0.996	0.000
H18.2 Other corneal oedema	0.004	0.996	0.000
L50.0 Allergic urticaria	0.004	0.996	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.004	0.996	0.000
H18.0 Corneal pigmentations and deposits	0.003	0.996	0.000
M81.0 Postmenopausal osteoporosis	0.003	0.996	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.996	0.004
H17.1 Other central corneal opacity	0.003	0.997	0.000
H17.0 Adherent leukoma	0.003	0.997	0.000
D23.7 Skin of lower limb, including hip	0.003	0.997	0.000
H18.5 Hereditary corneal dystrophies	0.003	0.997	0.000
M81.2 Osteoporosis of disuse	0.003	0.997	0.000
D48.0 Bone and articular cartilage	0.000	0.997	0.003
H18.7 Other corneal deformities	0.003	0.997	0.000
H18.3 Changes in corneal membranes	0.003	0.997	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.003	0.997	0.000
M81.48 Drug-induced osteoporosis (Other)	0.003	0.997	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.003	0.997	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.003	0.997	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.003	0.997	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.003	0.997	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.003	0.997	0.000
H18.1 Bullous keratopathy	0.003	0.997	0.000
M41.9 Scoliosis, unspecified	0.003	0.997	0.000
H16.4 Corneal neovascularisation	0.003	0.997	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.003	0.997	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.997	0.003
H16.3 Interstitial and deep keratitis	0.003	0.997	0.000
O14.9 Preeclampsia, unspecified	0.003	0.997	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.997	0.003
M41.99 Scoliosis, unspecified (Site unspecified)	0.003	0.997	0.000
T43.2 Other and unspecified antidepressants	0.000	0.997	0.003
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.003	0.997	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.003	0.997	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.003	0.997	0.000
T43.9 Psychotropic drug, unspecified	0.000	0.997	0.003
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.997	0.003
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.997	0.003
H15 Disorders of sclera	0.003	0.997	0.000
H90.5 Sensorineural hearing loss, unspecified	0.003	0.997	0.000
H90.2 Conductive hearing loss, unspecified	0.003	0.997	0.000
H17.8 Other corneal scars and opacities	0.003	0.997	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.997	0.003
T45.0 Antiallergic and antiemetic drugs	0.000	0.997	0.003
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.997	0.003
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.997	0.003
T42.3 Barbiturates	0.000	0.997	0.003
T42.2 Succinimides and oxazolidinediones	0.000	0.997	0.003
H18.4 Corneal degeneration	0.003	0.997	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.003	0.997	0.000
T43.6 Psychostimulants with abuse potential	0.000	0.997	0.003
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.997	0.003
T36 Poisoning by systemic antibiotics	0.000	0.997	0.003
T42.4 Benzodiazepines	0.000	0.997	0.003
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.003	0.997	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.003	0.997	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.003	0.997	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.003	0.997	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.003	0.997	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.003	0.997	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.003	0.997	0.000
H16.2 Keratoconjunctivitis	0.003	0.997	0.000
N48.4 Impotence of organic origin	0.003	0.997	0.000
Y85.0 Sequelae of motor-vehicle accident	0.000	0.997	0.003
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.997	0.003
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.003	0.997	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.003	0.997	0.000
M54.57 Low back pain (Lumbosacral region)	0.003	0.997	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.003	0.997	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.003	0.997	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.003	0.997	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.003	0.997	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.003	0.997	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.003	0.997	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.58 Idiopathic osteoporosis (Other)	0.003	0.997	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.003	0.997	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.003	0.997	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.003	0.997	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.003	0.997	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.003	0.997	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.003	0.997	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.003	0.997	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.003	0.997	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.003	0.997	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.003	0.997	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.003	0.997	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.003	0.997	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.003	0.997	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.003	0.997	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.003	0.997	0.000
M81.89 Other osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.88 Other osteoporosis (Other)	0.003	0.997	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.86 Other osteoporosis (Lower leg)	0.003	0.997	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.84 Other osteoporosis (Hand)	0.003	0.997	0.000
M81.83 Other osteoporosis (Forearm)	0.003	0.997	0.000
M81.82 Other osteoporosis (Upper arm)	0.003	0.997	0.000
M81.81 Other osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.80 Other osteoporosis (Multiple sites)	0.003	0.997	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.003	0.997	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.003	0.997	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.003	0.997	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.003	0.997	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.003	0.997	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.003	0.997	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.997	0.003
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.997	0.003
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.997	0.003
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.997	0.003
C69.3 Choroid	0.000	0.997	0.003
M41.92 Scoliosis, unspecified (Cervical region)	0.003	0.997	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.003	0.997	0.000
M81.28 Osteoporosis of disuse (Other)	0.003	0.997	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.003	0.997	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.003	0.997	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.003	0.997	0.000
M81.24 Osteoporosis of disuse (Hand)	0.003	0.997	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.003	0.997	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.003	0.997	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.003	0.997	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.003	0.997	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.003	0.997	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.997	0.003
D37.7 Other digestive organs	0.000	0.997	0.003
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.003	0.997	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.003	0.997	0.000
D05.7 Other carcinoma in situ of breast	0.003	0.997	0.000
T42.0 Hydantoin derivatives	0.000	0.997	0.003
H18.9 Disorder of cornea, unspecified	0.002	0.997	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.997	0.002
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.997	0.002
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.997	0.002
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.997	0.002
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.997	0.002
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.997	0.002
T44.0 Anticholinesterase agents	0.000	0.997	0.002
D05 Carcinoma in situ of breast	0.003	0.997	0.000
T36.0 Penicillins	0.000	0.997	0.003
M81.20 Osteoporosis of disuse (Multiple sites)	0.002	0.997	0.000
H15.0 Scleritis	0.002	0.997	0.000
G96.0 Cerebrospinal fluid leak	0.003	0.997	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.997	0.000
H90 Conductive and sensorineural hearing loss	0.003	0.997	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.997	0.003
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.002	0.997	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.002	0.997	0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.000	0.997	0.003
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.003	0.997	0.000
I82.8 Embolism and thrombosis of other specified veins	0.000	0.997	0.003
M05.9 Seropositive rheumatoid arthritis, unspecified	0.002	0.997	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.997	0.003
H15.9 Disorder of sclera, unspecified	0.002	0.997	0.000
D48.7 Other specified sites	0.000	0.997	0.002
L85.8 Other specified epidermal thickening	0.000	0.998	0.002
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.998	0.002
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.000	0.998	0.002
T36.9 Systemic antibiotic, unspecified	0.000	0.998	0.002
T36.8 Other systemic antibiotics	0.000	0.998	0.002
T36.7 Antifungal antibiotics, systemically used	0.000	0.998	0.002
T36.6 Rifamycins	0.000	0.998	0.002
T36.5 Aminoglycosides	0.000	0.998	0.002
T36.4 Tetracyclines	0.000	0.998	0.002
T36.3 Macrolides	0.000	0.998	0.002
T36.2 Chloramphenicol group	0.000	0.998	0.002
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.998	0.002
S72.30 Fracture of shaft of femur (closed)	0.002	0.998	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.002	0.998	0.000
R30.9 Painful micturition, unspecified	0.000	0.998	0.002
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.998	0.002
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.998	0.002
T45.8 Other primarily systemic and haematological agents	0.000	0.998	0.002
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.998	0.002
T45.6 Fibrinolysis-affecting drugs	0.000	0.998	0.002
T45.4 Iron and its compounds	0.000	0.998	0.002
T45.3 Enzymes, not elsewhere classified	0.000	0.998	0.002
H15.1 Episcleritis	0.002	0.998	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.002	0.998	0.000
H16.0 Corneal ulcer	0.002	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.998	0.002
T41.5 Therapeutic gases	0.000	0.998	0.002
T41.4 Anaesthetic, unspecified	0.000	0.998	0.002
T41.3 Local anaesthetics	0.000	0.998	0.002
T41.2 Other and unspecified general anaesthetics	0.000	0.998	0.002
T41.1 Intravenous anaesthetics	0.000	0.998	0.002
T41.0 Inhaled anaesthetics	0.000	0.998	0.002
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.998	0.002
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.998	0.002
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.998	0.002
T47.7 Emetics	0.000	0.998	0.002
T47.6 Antidiarrhoeal drugs	0.000	0.998	0.002
T47.5 Digestants	0.000	0.998	0.002
T47.4 Other laxatives	0.000	0.998	0.002
T47.3 Saline and osmotic laxatives	0.000	0.998	0.002
T47.0 Histamine H(2)-receptor antagonists	0.000	0.998	0.002
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.998	0.002
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.998	0.002
T48.5 Anti-common-cold drugs	0.000	0.998	0.002
T48.4 Expectorants	0.000	0.998	0.002
T48.3 Antitussives	0.000	0.998	0.002
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.998	0.002
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.998	0.002
T48.0 Oxytocic drugs	0.000	0.998	0.002
T49.9 Topical agent, unspecified	0.000	0.998	0.002
T49.8 Other topical agents	0.000	0.998	0.002
T49.7 Dental drugs, topically applied	0.000	0.998	0.002
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.998	0.002
T49.5 Ophthalmological drugs and preparations	0.000	0.998	0.002
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.998	0.002
T49.3 Emollients, demulcents and protectants	0.000	0.998	0.002
T49.2 Local astringents and local detergents	0.000	0.998	0.002
T49.1 Antipruritics	0.000	0.998	0.002
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.998	0.002
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.002	0.998	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.998	0.002
O36.5 Maternal care for poor foetal growth	0.002	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.998	0.002
T37.5 Antiviral drugs	0.000	0.998	0.002
T37.4 Anthelminthics	0.000	0.998	0.002
T37.3 Other antiprotozoal drugs	0.000	0.998	0.002
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.998	0.002
T37.1 Antimycobacterial drugs	0.000	0.998	0.002
T37.0 Sulphonamides	0.000	0.998	0.002
M96.0 Pseudarthrosis after fusion or arthrodesis	0.002	0.998	0.000
Z44.3 Fitting and adjustment of external breast prosthesis	0.002	0.998	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.002	0.998	0.000
H15.8 Other disorders of sclera	0.002	0.998	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.998	0.002
D03.4 Melanoma in situ of scalp and neck	0.002	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.002
H21 Other disorders of iris and ciliary body	0.002	0.998	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.998	0.002
T38.7 Androgens and anabolic congeners	0.000	0.998	0.002
T38.5 Other oestrogens and progestogens	0.000	0.998	0.002
T38.4 Oral contraceptives	0.000	0.998	0.002
T38.2 Antithyroid drugs	0.000	0.998	0.002
T38.0 Glucocorticoids and synthetic analogues	0.000	0.998	0.002
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
H90.3 Sensorineural hearing loss, bilateral	0.002	0.998	0.000
T38.1 Thyroid hormones and substitutes	0.000	0.998	0.002
K07.3 Anomalies of tooth position	0.000	0.998	0.002
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.002	0.998	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
T47.2 Stimulant laxatives	0.000	0.998	0.002
I62 Other nontraumatic intracranial haemorrhage	0.002	0.998	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.000	0.998	0.002
T45.5 Anticoagulants	0.000	0.998	0.002
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.002
D48.5 Skin	0.000	0.998	0.002
D48.4 Peritoneum	0.000	0.998	0.002
D48.3 Retroperitoneum	0.000	0.998	0.002
N76.8 Other specified inflammation of vagina and vulva	0.000	0.998	0.002
S83.2 Tear of meniscus, current	0.000	0.998	0.002
T45.2 Vitamins, not elsewhere classified	0.000	0.998	0.002
M21.27 Flexion deformity (Ankle and foot)	0.000	0.998	0.002
C15.9 Oesophagus, unspecified	0.002	0.998	0.000
M41 Scoliosis	0.002	0.998	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.002	0.998	0.000
H49.1 Fourth [trochlear] nerve palsy	0.002	0.998	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.002	0.998	0.000
Z97.8 Presence of other specified devices	0.000	0.998	0.002
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.002	0.998	0.000
D48.6 Breast	0.000	0.998	0.002
D03 Melanoma in situ	0.002	0.998	0.000
L50 Urticaria	0.002	0.998	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.002	0.998	0.000
S80-S89 Injuries to the knee and lower leg	0.002	0.998	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.000	0.998	0.002
L50.3 Dermatographic urticaria	0.002	0.998	0.000
M41.8 Other forms of scoliosis	0.002	0.998	0.000
R25.1 Tremor, unspecified	0.000	0.998	0.002
H21.4 Pupillary membranes	0.002	0.998	0.000
H21.0 Hyphaema	0.002	0.998	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.998	0.002
D03.2 Melanoma in situ of ear and external auricular canal	0.002	0.998	0.000
D03.0 Melanoma in situ of lip	0.002	0.998	0.000
D43.2 Brain, unspecified	0.000	0.998	0.002
Z98.8 Other specified postsurgical states	0.000	0.998	0.002
M41.86 Other forms of scoliosis (Lumbar region)	0.002	0.998	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.002	0.998	0.000
H21.2 Degeneration of iris and ciliary body	0.002	0.998	0.000
G24.9 Dystonia, unspecified	0.000	0.998	0.002
H90.0 Conductive hearing loss, bilateral	0.002	0.998	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.002	0.998	0.000
C15.5 Lower third of oesophagus	0.002	0.998	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.002	0.998	0.000
I05.9 Mitral valve disease, unspecified	0.000	0.998	0.002
T50.7 Analeptics and opioid receptor antagonists	0.000	0.998	0.002
T50.5 Appetite depressants	0.000	0.998	0.002
T50.4 Drugs affecting uric acid metabolism	0.000	0.998	0.002
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.998	0.002
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.998	0.002
T50.1 Loop [high-ceiling] diuretics	0.000	0.998	0.002
T50.0 Mineralocorticoids and their antagonists	0.000	0.998	0.002
D37-D48 Neoplasms of uncertain or unknown behaviour	0.000	0.998	0.002
O90.8 Other complications of the puerperium, not elsewhere classified	0.000	0.998	0.002
W25 Contact with sharp glass	0.000	0.998	0.002
D02.0 Larynx	0.002	0.998	0.000
D38.1 Trachea, bronchus and lung	0.000	0.998	0.002
I62.1 Nontraumatic extradural haemorrhage	0.002	0.998	0.000
M41.4 Neuromuscular scoliosis	0.002	0.998	0.000
M41.3 Thoracogenic scoliosis	0.002	0.998	0.000
M41.2 Other idiopathic scoliosis	0.002	0.998	0.000
M41.1 Juvenile idiopathic scoliosis	0.002	0.998	0.000
M41.0 Infantile idiopathic scoliosis	0.002	0.998	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.998	0.002
M21.24 Flexion deformity (Hand)	0.000	0.998	0.002
D48.2 Peripheral nerves and autonomic nervous system	0.000	0.998	0.001
H21.5 Other adhesions and disruptions of iris and ciliary body	0.002	0.998	0.000
I05.2 Mitral stenosis with insufficiency	0.000	0.998	0.002
Z75.2 Other waiting period for investigation and treatment	0.002	0.998	0.000
L50.1 Idiopathic urticaria	0.002	0.998	0.000
L50.6 Contact urticaria	0.002	0.998	0.000
L50.5 Cholinergic urticaria	0.002	0.998	0.000
L50.4 Vibratory urticaria	0.002	0.998	0.000
L50.2 Urticaria due to cold and heat	0.002	0.998	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.002	0.998	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.000	0.998	0.002
D03.9 Melanoma in situ, unspecified	0.002	0.998	0.000
D03.8 Melanoma in situ of other sites	0.002	0.998	0.000
D48.1 Connective and other soft tissue	0.000	0.998	0.002
M41.5 Other secondary scoliosis	0.002	0.998	0.000
S88 Traumatic amputation of lower leg	0.002	0.998	0.000
S87 Crushing injury of lower leg	0.002	0.998	0.000
S85 Injury of blood vessels at lower leg level	0.002	0.998	0.000
S84 Injury of nerves at lower leg level	0.002	0.998	0.000
L50.9 Urticaria, unspecified	0.002	0.998	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.000	0.998	0.002
M41.89 Other forms of scoliosis (Site unspecified)	0.001	0.998	0.000
M41.88 Other forms of scoliosis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M41.87 Other forms of scoliosis (Lumbosacral region)	0.001	0.998	0.000
M41.85 Other forms of scoliosis (Thoracolumbar region)	0.001	0.998	0.000
M41.84 Other forms of scoliosis (Thoracic region)	0.001	0.998	0.000
M41.83 Other forms of scoliosis (Cervicothoracic region)	0.001	0.998	0.000
M41.82 Other forms of scoliosis (Cervical region)	0.001	0.998	0.000
M41.81 Other forms of scoliosis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M41.80 Other forms of scoliosis (Multiple sites in spine)	0.001	0.998	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.002	0.998	0.000
I68.0 Cerebral amyloid angiopathy	0.002	0.998	0.000
T50.8 Diagnostic agents	0.000	0.998	0.001
C67.2 Lateral wall of bladder	0.002	0.998	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.001	0.998	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.002	0.998	0.000
C69 Malignant neoplasm of eye and adnexa	0.000	0.998	0.001
D05.0 Lobular carcinoma in situ	0.001	0.998	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.001	0.998	0.000
Q63.0 Accessory kidney	0.000	0.998	0.002
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.998	0.002
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.998	0.002
I05.1 Rheumatic mitral insufficiency	0.000	0.998	0.002
O14.2 HELLP syndrome	0.001	0.998	0.000
I05 Rheumatic mitral valve diseases	0.000	0.998	0.002
C69.9 Eye, unspecified	0.000	0.998	0.001
W25.6 Industrial and construction area	0.000	0.998	0.001
W25.5 Trade and service area	0.000	0.998	0.001
W25.1 Residential institution	0.000	0.998	0.001
W25.0 Home	0.000	0.998	0.001
W25.7 Farm	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations