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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3087243
log Bayes Factor = 41.252
Chromosome 2   position 204,738,919  (GRCh37) Explore rs3087243 on Ensembl!
Variant rs3087243 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.001 0.999
E06 Thyroiditis
0.000 0.014 0.986
E06.3 Autoimmune thyroiditis
0.000 0.047 0.953
E06.5 Other chronic thyroiditis
0.000 0.166 0.834
E06.9 Thyroiditis, unspecified
0.000 0.177 0.822
E10 Insulin-dependent diabetes mellitus
0.000 0.179 0.821
E10.1 With ketoacidosis
0.000 0.183 0.817
E10.9 Without complications
0.000 0.189 0.811
E03.1 Congenital hypothyroidism without goitre
0.000 0.195 0.805
E03.8 Other specified hypothyroidism
0.000 0.199 0.801
E10-E14 Diabetes mellitus
0.000 0.202 0.798
E05.8 Other thyrotoxicosis
0.000 0.203 0.797
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.203 0.797
E07 Other disorders of thyroid
0.000 0.222 0.778
E10.4 With neurological complications
0.000 0.267 0.733
E06.1 Subacute thyroiditis
0.000 0.278 0.722
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E10.2 With renal complications
0.000 0.288 0.712
E06.4 Drug-induced thyroiditis
0.000 0.293 0.707
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.293 0.707
E06.0 Acute thyroiditis
0.000 0.293 0.707
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.330 0.670
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.337 0.662
E10.8 With unspecified complications
0.000 0.362 0.638
E07.9 Disorder of thyroid, unspecified
0.000 0.376 0.624
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.378 0.622
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.389 0.611
E40-E46 Malnutrition
0.000 0.405 0.595
E10.7 With multiple complications
0.000 0.412 0.588
E12 Malnutrition-related diabetes mellitus
0.000 0.428 0.572
E07.1 Dyshormogenetic goitre
0.000 0.442 0.558
E07.0 Hypersecretion of calcitonin
0.000 0.442 0.558
E07.8 Other specified disorders of thyroid
0.000 0.449 0.551
E10.6 With other specified complications
0.000 0.456 0.543
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E16 Other disorders of pancreatic internal secretion
0.000 0.502 0.497
E13 Other specified diabetes mellitus
0.000 0.508 0.491
E50-E64 Other nutritional deficiencies
0.000 0.519 0.481
E46 Unspecified protein-energy malnutrition
0.000 0.549 0.451
E15 Nondiabetic hypoglycaemic coma
0.000 0.554 0.446
E61 Deficiency of other nutrient elements
0.000 0.561 0.439
E10.0 With coma
0.000 0.568 0.431
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.573 0.427
E45 Retarded development following protein-energy malnutrition
0.000 0.573 0.427
E43 Unspecified severe protein-energy malnutrition
0.000 0.573 0.427
E42 Marasmic kwashiorkor
0.000 0.573 0.427
E41 Nutritional marasmus
0.000 0.573 0.427
E40 Kwashiorkor
0.000 0.573 0.427
E14 Unspecified diabetes mellitus
0.000 0.574 0.426
E16.1 Other hypoglycaemia
0.000 0.589 0.411
E12.9 Without complications
0.000 0.590 0.410
E12.8 With unspecified complications
0.000 0.590 0.410
E12.7 With multiple complications
0.000 0.590 0.410
E12.6 With other specified complications
0.000 0.590 0.410
E12.5 With peripheral circulatory complications
0.000 0.590 0.410
E12.4 With neurological complications
0.000 0.590 0.410
E12.3 With ophthalmic complications
0.000 0.590 0.410
E12.2 With renal complications
0.000 0.590 0.410
E12.1 With ketoacidosis
0.000 0.590 0.410
E12.0 With coma
0.000 0.590 0.410
E61.1 Iron deficiency
0.000 0.593 0.407
E16.2 Hypoglycaemia, unspecified
0.000 0.595 0.405
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.612 0.387
E10.3 With ophthalmic complications
0.000 0.635 0.365
E14.4 With neurological complications
0.000 0.640 0.360
E10.5 With peripheral circulatory complications
0.000 0.641 0.359
E14.2 Withrenal complications
0.000 0.642 0.358
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.643 0.357
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.643 0.357
E16.4 Abnormal secretion of gastrin
0.000 0.643 0.357
E16.3 Increased secretion of glucagon
0.000 0.643 0.357
E13.8 With unspecified complications
0.000 0.647 0.352
E13.7 With multiple complications
0.000 0.647 0.352
E13.6 With other specified complications
0.000 0.647 0.352
E13.5 With peripheral circulatory complications
0.000 0.647 0.352
E13.4 With neurological complications
0.000 0.647 0.352
E13.2 With renal complications
0.000 0.647 0.352
E13.1 With ketoacidosis
0.000 0.647 0.352
E13.0 With coma
0.000 0.647 0.352
E11 Non-insulin-dependent diabetes mellitus
0.000 0.649 0.351
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.655 0.345
E63 Other nutritional deficiencies
0.000 0.655 0.345
E50 Vitamin A deficiency
0.000 0.655 0.345
E60 Dietary zinc deficiency
0.000 0.655 0.345
E59 Dietary selenium deficiency
0.000 0.655 0.345
E54 Ascorbic acid deficiency
0.000 0.655 0.345
E52 Niacin deficiency [pellagra]
0.000 0.655 0.345
E58 Dietary calcium deficiency
0.000 0.655 0.345
E14.8 With unspecified complications
0.000 0.661 0.339
E56 Other vitamin deficiencies
0.000 0.663 0.337
E13.9 Without complications
0.000 0.667 0.333
E11.2 With renal complications
0.000 0.671 0.329
E61.2 Magnesium deficiency
0.000 0.676 0.324
G81.9 Hemiplegia, unspecified
0.323 0.677 0.000
E51 Thiamine deficiency
0.000 0.677 0.322
E61.9 Deficiency of nutrient element, unspecified
0.000 0.685 0.315
E61.8 Deficiency of other specified nutrient elements
0.000 0.685 0.315
E61.7 Deficiency of multiple nutrient elements
0.000 0.685 0.315
E61.6 Vanadium deficiency
0.000 0.685 0.315
E61.5 Molybdenum deficiency
0.000 0.685 0.315
E61.4 Chromium deficiency
0.000 0.685 0.315
E61.3 Manganese deficiency
0.000 0.685 0.315
E61.0 Copper deficiency
0.000 0.685 0.315
E14.5 With peripheral circulatory complications
0.000 0.687 0.313
E44.1 Mild protein-energy malnutrition
0.000 0.694 0.306
E44.0 Moderate protein-energy malnutrition
0.000 0.694 0.306
E14.7 With multiple complications
0.000 0.694 0.306
E11.5 With peripheral circulatory complications
0.000 0.696 0.304
E13.3 With ophthalmic complications
0.000 0.701 0.299
E20-E35 Disorders of other endocrine glands
0.000 0.705 0.295
E11.4 With neurological complications
0.000 0.718 0.282
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.725 0.274
E14.3 With ophthalmic complications
0.000 0.726 0.274
G81 Hemiplegia
0.272 0.728 0.000
E14.6 With other specified complications
0.000 0.730 0.270
E14.0 With coma
0.000 0.734 0.266
E14.1 With ketoacidosis
0.000 0.746 0.253
E65-E68 Obesity and other hyperalimentation
0.001 0.748 0.251
E11.7 With multiple complications
0.000 0.748 0.252
E28 Ovarian dysfunction
0.000 0.751 0.249
E27 Other disorders of adrenal gland
0.000 0.752 0.248
E50.9 Vitamin A deficiency, unspecified
0.000 0.752 0.248
E50.8 Other manifestations of vitamin A deficiency
0.000 0.752 0.248
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.752 0.248
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.752 0.248
E50.5 Vitamin A deficiency with night blindness
0.000 0.752 0.248
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.752 0.248
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.752 0.248
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.752 0.248
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.752 0.248
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.752 0.248
E63.9 Nutritional deficiency, unspecified
0.000 0.752 0.248
E63.8 Other specified nutritional deficiencies
0.000 0.752 0.248
E63.1 Imbalance of constituents of food intake
0.000 0.752 0.248
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.752 0.248
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.752 0.248
E64.8 Sequelae of other nutritional deficiencies
0.000 0.752 0.248
E64.3 Sequelae of rickets
0.000 0.752 0.248
E64.2 Sequelae of vitamin C deficiency
0.000 0.752 0.248
E64.1 Sequelae of vitamin A deficiency
0.000 0.752 0.248
E64.0 Sequelae of protein-energy malnutrition
0.000 0.752 0.248
E56.9 Vitamin deficiency, unspecified
0.000 0.758 0.241
E56.8 Deficiency of other vitamins
0.000 0.758 0.241
E56.0 Deficiency of vitamin E
0.000 0.758 0.241
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.764 0.236
E56.1 Deficiency of vitamin K
0.000 0.767 0.233
E51.9 Thiamine deficiency, unspecified
0.000 0.769 0.231
E51.8 Other manifestations of thiamine deficiency
0.000 0.769 0.231
E51.1 Beriberi
0.000 0.769 0.231
G80-G83 Cerebral palsy and other paralytic syndromes
0.229 0.771 0.000
E55 Vitamin D deficiency
0.000 0.771 0.229
G80 Infantile cerebral palsy
0.224 0.776 0.000
E11.3 With ophthalmic complications
0.000 0.776 0.224
E11.6 With other specified complications
0.000 0.781 0.219
E22 Hyperfunction of pituitary gland
0.000 0.784 0.216
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.788 0.212
E32 Diseases of thymus
0.000 0.788 0.212
E31 Polyglandular dysfunction
0.000 0.788 0.212
E30 Disorders of puberty, not elsewhere classified
0.000 0.788 0.212
E51.2 Wernicke's encephalopathy
0.000 0.791 0.208
E34 Other endocrine disorders
0.000 0.791 0.209
E28.3 Primary ovarian failure
0.000 0.792 0.208
G81.1 Spastic hemiplegia
0.207 0.793 0.000
G80.9 Infantile cerebral palsy, unspecified
0.207 0.793 0.000
E20 Hypoparathyroidism
0.000 0.795 0.205
E27.2 Addisonian crisis
0.000 0.796 0.204
I85.9 Oesophageal varices without bleeding
0.000 0.801 0.199
E29 Testicular dysfunction
0.000 0.801 0.198
E27.1 Primary adrenocortical insufficiency
0.000 0.803 0.197
G81.0 Flaccid hemiplegia
0.195 0.805 0.000
I85 Oesophageal varices
0.000 0.807 0.193
E11.8 With unspecified complications
0.000 0.808 0.192
E28.2 Polycystic ovarian syndrome
0.000 0.808 0.192
G80.2 Infantile hemiplegia
0.190 0.810 0.000
G80.8 Other infantile cerebral palsy
0.188 0.812 0.000
I85.0 Oesophageal varices with bleeding
0.000 0.813 0.187
E67 Other hyperalimentation
0.001 0.819 0.180
E68 Sequelae of hyperalimentation
0.001 0.819 0.180
E23 Hypofunction and other disorders of pituitary gland
0.000 0.820 0.180
E28.9 Ovarian dysfunction, unspecified
0.000 0.821 0.179
E28.8 Other ovarian dysfunction
0.000 0.821 0.179
E28.1 Androgen excess
0.000 0.821 0.179
E28.0 Oestrogen excess
0.000 0.821 0.179
E27.5 Adrenomedullary hyperfunction
0.000 0.822 0.178
E27.0 Other adrenocortical overactivity
0.000 0.822 0.178
E34.8 Other specified endocrine disorders
0.000 0.823 0.177
E25 Adrenogenital disorders
0.000 0.825 0.175
G80.1 Spastic diplegia
0.175 0.825 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.827 0.173
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.829 0.171
E53 Deficiency of other B group vitamins
0.000 0.833 0.167
E24 Cushing's syndrome
0.000 0.833 0.167
E11.1 With ketoacidosis
0.000 0.834 0.166
E55.0 Rickets, active
0.000 0.836 0.164
G83 Other paralytic syndromes
0.164 0.836 0.000
G80.0 Spastic cerebral palsy
0.162 0.838 0.000
G80.4 Ataxic cerebral palsy
0.161 0.839 0.000
G80.3 Dyskinetic cerebral palsy
0.161 0.839 0.000
E26 Hyperaldosteronism
0.000 0.843 0.156
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.845 0.155
E22.8 Other hyperfunction of pituitary gland
0.000 0.845 0.155
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.846 0.154
E30.9 Disorder of puberty, unspecified
0.000 0.848 0.152
E30.8 Other disorders of puberty
0.000 0.848 0.152
E30.1 Precocious puberty
0.000 0.848 0.152
E30.0 Delayed puberty
0.000 0.848 0.152
E31.9 Polyglandular dysfunction, unspecified
0.000 0.848 0.152
E31.8 Other polyglandular dysfunction
0.000 0.848 0.152
E31.1 Polyglandular hyperfunction
0.000 0.848 0.152
E31.0 Autoimmune polyglandular failure
0.000 0.848 0.152
E32.9 Disease of thymus, unspecified
0.000 0.848 0.152
E32.8 Other diseases of thymus
0.000 0.848 0.152
E32.1 Abscess of thymus
0.000 0.848 0.152
E32.0 Persistent hyperplasia of thymus
0.000 0.848 0.152
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.848 0.152
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.848 0.152
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.848 0.152
I81 Portal vein thrombosis
0.000 0.849 0.151
E34.5 Androgen resistance syndrome
0.000 0.850 0.150
E34.4 Constitutional tall stature
0.000 0.850 0.150
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.850 0.150
E34.1 Other hypersecretion of intestinal hormones
0.000 0.850 0.150
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.851 0.149
G83.4 Cauda equina syndrome
0.149 0.851 0.000
E20.8 Other hypoparathyroidism
0.000 0.853 0.147
E20.1 Pseudohypoparathyroidism
0.000 0.853 0.147
E20.0 Idiopathic hypoparathyroidism
0.000 0.853 0.147
E22.1 Hyperprolactinaemia
0.000 0.855 0.144
E34.0 Carcinoid syndrome
0.000 0.857 0.143
E29.9 Testicular dysfunction, unspecified
0.000 0.857 0.142
E29.8 Other testicular dysfunction
0.000 0.857 0.142
E29.0 Testicular hyperfunction
0.000 0.857 0.142
E34.3 Short stature, not elsewhere classified
0.000 0.858 0.142
I80 Phlebitis and thrombophlebitis
0.000 0.859 0.141
E23.7 Disorder of pituitary gland, unspecified
0.000 0.859 0.141
E20.9 Hypoparathyroidism, unspecified
0.000 0.859 0.141
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.864 0.136
I82 Other venous embolism and thrombosis
0.000 0.865 0.135
E65 Localised adiposity
0.001 0.865 0.135
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.866 0.134
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.868 0.132
I88 Nonspecific lymphadenitis
0.000 0.868 0.132
E23.2 Diabetes insipidus
0.000 0.868 0.132
E67.8 Other specified hyperalimentation
0.001 0.870 0.129
E67.3 Hypervitaminosis D
0.001 0.870 0.129
E67.2 Megavitamin-B6 syndrome
0.001 0.870 0.129
E67.1 Hypercarotenaemia
0.001 0.870 0.129
E67.0 Hypervitaminosis A
0.001 0.870 0.129
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.871 0.129
E23.1 Drug-induced hypopituitarism
0.000 0.871 0.129
E29.1 Testicular hypofunction
0.000 0.871 0.129
E25.9 Adrenogenital disorder, unspecified
0.000 0.874 0.126
E25.8 Other adrenogenital disorders
0.000 0.874 0.126
I89.0 Lymphoedema, not elsewhere classified
0.000 0.876 0.124
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.879 0.121
E53.1 Pyridoxine deficiency
0.000 0.880 0.120
E53.0 Riboflavin deficiency
0.000 0.880 0.120
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.880 0.120
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.880 0.120
E24.3 Ectopic ACTH syndrome
0.000 0.880 0.120
E24.1 Nelson's syndrome
0.000 0.880 0.120
E24.2 Drug-induced Cushing's syndrome
0.000 0.882 0.118
G83.5 Locked-in syndrome
0.118 0.882 0.000
G83.3 Monoplegia, unspecified
0.118 0.882 0.000
G83.0 Diplegia of upper limbs
0.118 0.882 0.000
E34.9 Endocrine disorder, unspecified
0.000 0.883 0.116
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.884 0.116
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.886 0.114
E26.8 Other hyperaldosteronism
0.000 0.887 0.112
E26.1 Secondary hyperaldosteronism
0.000 0.887 0.112
E11.0 With coma
0.001 0.888 0.111
G83.9 Paralytic syndrome, unspecified
0.111 0.889 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.889 0.110
G83.8 Other specified paralytic syndromes
0.110 0.890 0.000
I82.2 Embolism and thrombosis of vena cava
0.000 0.890 0.110
E24.8 Other Cushing's syndrome
0.000 0.891 0.109
E23.0 Hypopituitarism
0.000 0.893 0.107
E24.0 Pituitary-dependent Cushing's disease
0.000 0.894 0.106
E26.9 Hyperaldosteronism, unspecified
0.000 0.895 0.105
E04 Other non-toxic goitre
0.000 0.896 0.104
E27.8 Other specified disorders of adrenal gland
0.000 0.898 0.102
I82.3 Embolism and thrombosis of renal vein
0.000 0.899 0.101
E23.6 Other disorders of pituitary gland
0.000 0.901 0.099
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.902 0.098
G82 Paraplegia and tetraplegia
0.097 0.903 0.000
I82.1 Thrombophlebitis migrans
0.000 0.903 0.097
I88.8 Other nonspecific lymphadenitis
0.000 0.904 0.096
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.905 0.095
I82.0 Budd-Chiari syndrome
0.000 0.905 0.095
G83.1 Monoplegia of lower limb
0.094 0.906 0.000
G83.2 Monoplegia of upper limb
0.093 0.907 0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.909 0.090
G25.8 Other specified extrapyramidal and movement disorders
0.090 0.910 0.000
E21.0 Primary hyperparathyroidism
0.000 0.910 0.090
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.911 0.089
G25 Other extrapyramidal and movement disorders
0.089 0.911 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.912 0.088
G20-G26 Extrapyramidal and movement disorders
0.088 0.912 0.000
I89.1 Lymphangitis
0.000 0.915 0.085
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.916 0.084
E21.4 Other specified disorders of parathyroid gland
0.000 0.916 0.083
G25.0 Essential tremor
0.083 0.917 0.000
I82.8 Embolism and thrombosis of other specified veins
0.000 0.920 0.080
E53.9 Vitamin B deficiency, unspecified
0.001 0.920 0.079
G24 Dystonia
0.080 0.920 0.000
G20 Parkinson's disease
0.079 0.921 0.000
E21.2 Other hyperparathyroidism
0.000 0.922 0.077
E04.0 Non-toxic diffuse goitre
0.000 0.922 0.077
G30.9 Alzheimer's disease, unspecified
0.075 0.925 0.000
E04.8 Other specified non-toxic goitre
0.000 0.925 0.075
G30 Alzheimer's disease
0.074 0.926 0.000
G82.4 Spastic tetraplegia
0.073 0.927 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.073 0.927 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.072 0.928 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.928 0.072
E26.0 Primary hyperaldosteronism
0.001 0.929 0.071
Chapter VI Diseases of the nervous system
0.071 0.929 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.071 0.929 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.929 0.070
G30-G32 Other degenerative diseases of the nervous system
0.070 0.930 0.000
G82.3 Flaccid tetraplegia
0.070 0.930 0.000
G82.0 Flaccid paraplegia
0.070 0.930 0.000
E27.9 Disorder of adrenal gland, unspecified
0.001 0.930 0.069
E89.0 Postprocedural hypothyroidism
0.000 0.932 0.068
G23 Other degenerative diseases of basal ganglia
0.067 0.933 0.000
G24.9 Dystonia, unspecified
0.067 0.933 0.000
G24.5 Blepharospasm
0.067 0.933 0.000
G82.5 Tetraplegia, unspecified
0.067 0.933 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.934 0.066
G25.9 Extrapyramidal and movement disorder, unspecified
0.066 0.934 0.000
E70-E90 Metabolic disorders
0.000 0.934 0.066
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.064 0.936 0.000
G25.6 Drug-induced tics and other tics of organic origin
0.064 0.936 0.000
G25.4 Drug-induced chorea
0.064 0.936 0.000
G25.1 Drug-induced tremor
0.064 0.936 0.000
G25.5 Other chorea
0.063 0.937 0.000
G30.0 Alzheimer's disease with early onset
0.063 0.937 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.063 0.937 0.000
G22 Parkinsonism in diseases classified elsewhere
0.063 0.937 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.937 0.063
I83 Varicose veins of lower extremities
0.000 0.939 0.061
G24.1 Idiopathic familial dystonia
0.060 0.940 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.060 0.940 0.000
G24.3 Spasmodic torticollis
0.060 0.940 0.000
I86 Varicose veins of other sites
0.002 0.941 0.057
G21 Secondary Parkinsonism
0.058 0.942 0.000
G24.4 Idiopathic orofacial dystonia
0.057 0.943 0.000
G24.2 Idiopathic nonfamilial dystonia
0.057 0.943 0.000
G24.0 Drug-induced dystonia
0.057 0.943 0.000
G25.2 Other specified forms of tremor
0.057 0.943 0.000
G24.8 Other dystonia
0.056 0.944 0.000
G30.8 Other Alzheimer's disease
0.055 0.945 0.000
E89.2 Postprocedural hypoparathyroidism
0.000 0.945 0.055
G82.1 Spastic paraplegia
0.054 0.946 0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.054 0.946 0.000
E89.3 Postprocedural hypopituitarism
0.000 0.947 0.053
G23.8 Other specified degenerative diseases of basal ganglia
0.052 0.948 0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.052 0.948 0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.052 0.948 0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.052 0.948 0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.052 0.948 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.948 0.052
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.949 0.051
G30.1 Alzheimer's disease with late onset
0.051 0.949 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.051 0.949 0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.049 0.950 0.000
G23.9 Degenerative disease of basal ganglia, unspecified
0.048 0.951 0.000
G23.3 Multiple system atrophy, cerebellar type
0.048 0.951 0.000
G23.2 Striatonigral degeneration
0.048 0.951 0.000
G23.0 Hallervorden-Spatz disease
0.048 0.951 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.952 0.048
E84 Cystic fibrosis
0.000 0.952 0.048
I86.4 Gastric varices
0.001 0.952 0.047
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.952 0.048
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.952 0.048
E55.9 Vitamin D deficiency, unspecified
0.000 0.953 0.047
E77 Disorders of glycoprotein metabolism
0.000 0.953 0.047
E76 Disorders of glycosaminoglycan metabolism
0.000 0.953 0.047
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.953 0.047
E70 Disorders of aromatic amino-acid metabolism
0.000 0.953 0.047
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.953 0.047
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.000 0.954 0.046
G00-G09 Inflammatory diseases of the central nervous system
0.046 0.954 0.000
E85 Amyloidosis
0.000 0.954 0.046
C50.9 Breast, unspecified
0.000 0.954 0.046
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.954 0.046
E53.8 Deficiency of other specified B group vitamins
0.000 0.955 0.045
E89.4 Postprocedural ovarian failure
0.000 0.955 0.045
E87.2 Acidosis
0.000 0.955 0.045
E21.3 Hyperparathyroidism, unspecified
0.000 0.955 0.045
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.956 0.044
E89.5 Postprocedural testicular hypofunction
0.000 0.956 0.044
I86.3 Vulval varices
0.001 0.956 0.042
E89.1 Postprocedural hypoinsulinaemia
0.000 0.957 0.043
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.957 0.043
E79 Disorders of purine and pyrimidine metabolism
0.000 0.957 0.042
I86.0 Sublingual varices
0.002 0.958 0.041
M46 Other inflammatory spondylopathies
0.042 0.958 0.000
G21.9 Secondary Parkinsonism, unspecified
0.041 0.958 0.000
G21.8 Other secondary Parkinsonism
0.041 0.958 0.000
G21.3 Postencephalitic Parkinsonism
0.041 0.958 0.000
G21.2 Secondary Parkinsonism due to other external agents
0.041 0.958 0.000
G21.0 Malignant neuroleptic syndrome
0.041 0.958 0.000
E72 Other disorders of amino-acid metabolism
0.000 0.958 0.041
G21.4 Vascular parkinsonism
0.040 0.959 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.960 0.040
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.960 0.040
G04 Encephalitis, myelitis and encephalomyelitis
0.039 0.961 0.000
E87.0 Hyperosmolality and hypernatraemia
0.000 0.961 0.039
G01 Meningitis in bacterial diseases classified elsewhere
0.038 0.962 0.000
E85.9 Amyloidosis, unspecified
0.000 0.962 0.038
E74 Other disorders of carbohydrate metabolism
0.000 0.962 0.038
M06.9 Rheumatoid arthritis, unspecified
0.000 0.962 0.038
G82.2 Paraplegia, unspecified
0.038 0.962 0.000
E73 Lactose intolerance
0.000 0.962 0.038
G21.1 Other drug-induced secondary Parkinsonism
0.037 0.962 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.963 0.037
K90.0 Coeliac disease
0.000 0.963 0.037
E80.2 Other porphyria
0.000 0.963 0.037
E87.4 Mixed disorder of acid-base balance
0.000 0.963 0.037
E87.5 Hyperkalaemia
0.000 0.963 0.037
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.037 0.963 0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.036 0.963 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.037 0.963 0.000
M46.4 Discitis, unspecified
0.036 0.964 0.000
I86.2 Pelvic varices
0.002 0.964 0.034
E84.9 Cystic fibrosis, unspecified
0.000 0.964 0.036
E85.8 Other amyloidosis
0.000 0.965 0.035
E87.3 Alkalosis
0.000 0.965 0.035
E84.8 Cystic fibrosis with other manifestations
0.000 0.965 0.035
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.965 0.035
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.965 0.035
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.034 0.966 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.034 0.966 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.034 0.966 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.966 0.034
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.966 0.034
E70.3 Albinism
0.000 0.966 0.034
E70.2 Disorders of tyrosine metabolism
0.000 0.966 0.034
E70.1 Other hyperphenylalaninaemias
0.000 0.966 0.034
E70.0 Classical phenylketonuria
0.000 0.966 0.034
E71.3 Disorders of fatty-acid metabolism
0.000 0.966 0.034
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.966 0.034
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.966 0.034
E71.0 Maple-syrup-urine disease
0.000 0.966 0.034
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.966 0.034
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.966 0.034
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.966 0.034
E76.2 Other mucopolysaccharidoses
0.000 0.966 0.034
E76.1 Mucopolysaccharidosis, type II
0.000 0.966 0.034
E76.0 Mucopolysaccharidosis, type I
0.000 0.966 0.034
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.966 0.034
E77.8 Other disorders of glycoprotein metabolism
0.000 0.966 0.034
E77.1 Defects in glycoprotein degradation
0.000 0.966 0.034
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.966 0.034
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.033 0.967 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.967 0.033
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.967 0.033
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.967 0.033
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.967 0.033
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.967 0.033
E80.5 Crigler-Najjar syndrome
0.000 0.967 0.033
E80.3 Defects of catalase and peroxydase
0.000 0.967 0.033
E80.0 Hereditary erythropoietic porphyria
0.000 0.967 0.033
M46.0 Spinal enthesopathy
0.033 0.967 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.033 0.967 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.033 0.967 0.000
E80.1 Porphyria cutanea tarda
0.000 0.967 0.033
E80.6 Other disorders of bilirubin metabolism
0.000 0.967 0.033
Z80.4 Family history of malignant neoplasm of genital organs
0.032 0.968 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.968 0.032
E75.6 Lipid storage disorder, unspecified
0.000 0.968 0.032
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.968 0.032
E75.3 Sphingolipidosis, unspecified
0.000 0.968 0.032
E75.1 Other gangliosidosis
0.000 0.968 0.032
E75.0 GM2 gangliosidosis
0.000 0.968 0.032
M46.42 Discitis, unspecified (Cervical region)
0.031 0.968 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.969 0.031
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.969 0.031
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.969 0.031

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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