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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3093553
log Bayes Factor = 57.9449
Chromosome 6   position 31,549,556  (GRCh37) Explore rs3093553 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
J47 Bronchiectasis
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
J33.9 Nasal polyp, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.001 0.999
J30-J39 Other diseases of upper respiratory tract
0.000 0.001 0.999
J45 Asthma
0.000 0.001 0.999
Chapter X Diseases of the respiratory system
0.000 0.001 0.999
J45.9 Asthma, unspecified
0.000 0.002 0.998
E05.9 Thyrotoxicosis, unspecified
0.000 0.003 0.997
E10-E14 Diabetes mellitus
0.000 0.003 0.997
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.004 0.996
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.004 0.996
J33.0 Polyp of nasal cavity
0.000 0.006 0.994
E03 Other hypothyroidism
0.000 0.010 0.990
E03.9 Hypothyroidism, unspecified
0.000 0.016 0.984
L40.0 Psoriasis vulgaris
0.982 0.018 0.000
J44 Other chronic obstructive pulmonary disease
0.000 0.025 0.975
E10.3 With ophthalmic complications
0.000 0.030 0.970
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.044 0.956
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.047 0.953
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.049 0.951
E07 Other disorders of thyroid
0.000 0.050 0.950
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.071 0.929
E10.4 With neurological complications
0.000 0.073 0.927
E07.9 Disorder of thyroid, unspecified
0.000 0.078 0.922
E10.1 With ketoacidosis
0.000 0.086 0.914
J31.0 Chronic rhinitis
0.000 0.088 0.912
J33.8 Other polyp of sinus
0.000 0.097 0.903
J84 Other interstitial pulmonary diseases
0.000 0.108 0.892
E14 Unspecified diabetes mellitus
0.000 0.119 0.881
E16 Other disorders of pancreatic internal secretion
0.000 0.120 0.880
J32 Chronic sinusitis
0.000 0.138 0.862
L40.1 Generalised pustular psoriasis
0.853 0.147 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.154 0.846
E16.2 Hypoglycaemia, unspecified
0.000 0.154 0.846
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.162 0.838
J45.0 Predominantly allergic asthma
0.000 0.179 0.821
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.180 0.820
E10.5 With peripheral circulatory complications
0.000 0.183 0.817
J80 Adult respiratory distress syndrome
0.000 0.209 0.791
L40.8 Other psoriasis
0.789 0.211 0.000
J00-J06 Acute upper respiratory infections
0.000 0.224 0.776
J30 Vasomotor and allergic rhinitis
0.000 0.227 0.773
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.227 0.772
J31.2 Chronic pharyngitis
0.000 0.231 0.769
E14.3 With ophthalmic complications
0.000 0.252 0.748
E06 Thyroiditis
0.000 0.254 0.746
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.258 0.742
J32.0 Chronic maxillary sinusitis
0.000 0.271 0.729
J60-J70 Lung diseases due to external agents
0.000 0.273 0.727
J32.4 Chronic pansinusitis
0.000 0.274 0.726
E14.9 Without complications
0.000 0.276 0.724
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.000 0.283 0.717
J33.1 Polypoid sinus degeneration
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.2 With renal complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E05.8 Other thyrotoxicosis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
J45.8 Mixed asthma
0.000 0.284 0.716
J45.1 Nonallergic asthma
0.000 0.284 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.285 0.715
E03.5 Myxoedema coma
0.000 0.290 0.710
E03.4 Atrophy of thyroid (acquired)
0.000 0.290 0.710
E03.3 Postinfectious hypothyroidism
0.000 0.290 0.710
E03.1 Congenital hypothyroidism without goitre
0.000 0.290 0.710
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.290 0.710
J81 Pulmonary oedema
0.000 0.291 0.709
J39 Other diseases of upper respiratory tract
0.000 0.291 0.709
E03.8 Other specified hypothyroidism
0.000 0.298 0.702
J03 Acute tonsillitis
0.000 0.311 0.689
J31.1 Chronic nasopharyngitis
0.000 0.314 0.686
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.317 0.683
E10.8 With unspecified complications
0.000 0.317 0.683
E07.1 Dyshormogenetic goitre
0.000 0.319 0.681
E07.0 Hypersecretion of calcitonin
0.000 0.319 0.681
K90 Intestinal malabsorption
0.000 0.319 0.681
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.329 0.671
E15 Nondiabetic hypoglycaemic coma
0.000 0.334 0.666
J32.2 Chronic ethmoidal sinusitis
0.000 0.335 0.665
M07.3 Other psoriatic arthropathies
0.663 0.337 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.662 0.338 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.661 0.339 0.000
J42 Unspecified chronic bronchitis
0.000 0.344 0.656
J37 Chronic laryngitis and laryngotracheitis
0.000 0.347 0.653
J35 Chronic diseases of tonsils and adenoids
0.000 0.357 0.643
J84.8 Other specified interstitial pulmonary diseases
0.000 0.360 0.640
J84.0 Alveolar and parietoalveolar conditions
0.000 0.360 0.640
E14.8 With unspecified complications
0.000 0.369 0.631
E14.7 With multiple complications
0.000 0.369 0.631
E14.6 With other specified complications
0.000 0.369 0.631
E14.5 With peripheral circulatory complications
0.000 0.369 0.631
E14.4 With neurological complications
0.000 0.369 0.631
E14.2 Withrenal complications
0.000 0.369 0.631
E14.1 With ketoacidosis
0.000 0.369 0.631
E14.0 With coma
0.000 0.369 0.631
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.369 0.631
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.369 0.631
E16.4 Abnormal secretion of gastrin
0.000 0.369 0.631
E16.3 Increased secretion of glucagon
0.000 0.369 0.631
E16.1 Other hypoglycaemia
0.000 0.369 0.631
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.369 0.631
E50-E64 Other nutritional deficiencies
0.000 0.371 0.629
J46 Status asthmaticus
0.000 0.372 0.628
J03.9 Acute tonsillitis, unspecified
0.000 0.373 0.627
K90.9 Intestinal malabsorption, unspecified
0.000 0.378 0.622
J36 Peritonsillar abscess
0.000 0.381 0.619
J32.8 Other chronic sinusitis
0.000 0.382 0.618
J32.3 Chronic sphenoidal sinusitis
0.000 0.382 0.618
J01 Acute sinusitis
0.000 0.385 0.615
J86 Pyothorax
0.000 0.390 0.610
E07.8 Other specified disorders of thyroid
0.000 0.390 0.609
E40-E46 Malnutrition
0.000 0.395 0.605
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.404 0.596
J30.3 Other allergic rhinitis
0.000 0.419 0.581
E13 Other specified diabetes mellitus
0.000 0.425 0.574
J30.4 Allergic rhinitis, unspecified
0.000 0.426 0.574
J00 Acute nasopharyngitis [common cold]
0.000 0.427 0.573
J30.1 Allergic rhinitis due to pollen
0.000 0.431 0.569
E06.3 Autoimmune thyroiditis
0.000 0.436 0.564
J39.2 Other diseases of pharynx
0.000 0.437 0.563
J32.1 Chronic frontal sinusitis
0.000 0.443 0.557
J30.2 Other seasonal allergic rhinitis
0.000 0.446 0.554
J30.0 Vasomotor rhinitis
0.000 0.446 0.554
J85 Abscess of lung and mediastinum
0.000 0.446 0.554
M07.34 Other psoriatic arthropathies (Hand)
0.547 0.453 0.000
J20-J22 Other acute lower respiratory infections
0.000 0.454 0.546
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.546 0.454 0.000
J32.9 Chronic sinusitis, unspecified
0.000 0.458 0.542
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.462 0.538
E06.9 Thyroiditis, unspecified
0.000 0.465 0.535
E06.5 Other chronic thyroiditis
0.000 0.465 0.535
E06.4 Drug-induced thyroiditis
0.000 0.465 0.535
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.465 0.535
E06.1 Subacute thyroiditis
0.000 0.465 0.535
E06.0 Acute thyroiditis
0.000 0.465 0.535
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.469 0.531
E04 Other non-toxic goitre
0.000 0.469 0.531
M07.36 Other psoriatic arthropathies (Lower leg)
0.531 0.469 0.000
J35.1 Hypertrophy of tonsils
0.000 0.473 0.527
J01.9 Acute sinusitis, unspecified
0.000 0.476 0.524
J70 Respiratory conditions due to other external agents
0.000 0.478 0.522
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.478 0.522
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.478 0.522
J66 Airway disease due to specific organic dust
0.000 0.478 0.522
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.478 0.522
J62 Pneumoconiosis due to dust containing silica
0.000 0.478 0.522
J65 Pneumoconiosis associated with tuberculosis
0.000 0.478 0.522
J64 Unspecified pneumoconiosis
0.000 0.478 0.522
J60 Coalworker's pneumoconiosis
0.000 0.478 0.522
J40 Bronchitis, not specified as acute or chronic
0.000 0.481 0.519
J04 Acute laryngitis and tracheitis
0.000 0.482 0.518
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.1 Mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.0 Simple chronic bronchitis
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.487 0.512
E12.8 With unspecified complications
0.000 0.487 0.512
E12.7 With multiple complications
0.000 0.487 0.512
E12.6 With other specified complications
0.000 0.487 0.512
E12.5 With peripheral circulatory complications
0.000 0.487 0.512
E12.4 With neurological complications
0.000 0.487 0.512
E12.3 With ophthalmic complications
0.000 0.487 0.512
E12.2 With renal complications
0.000 0.487 0.512
E12.1 With ketoacidosis
0.000 0.487 0.512
E12.0 With coma
0.000 0.487 0.512
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.489 0.511
J39.9 Disease of upper respiratory tract, unspecified
0.000 0.492 0.508
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified
0.000 0.492 0.508
J39.1 Other abscess of pharynx
0.000 0.492 0.508
J39.0 Retropharyngeal and parapharyngeal abscess
0.000 0.492 0.508
J03.8 Acute tonsillitis due to other specified organisms
0.000 0.506 0.494
J03.0 Streptococcal tonsillitis
0.000 0.506 0.494
J86.9 Pyothorax without fistula
0.000 0.506 0.494
K90.8 Other intestinal malabsorption
0.000 0.512 0.488
K90.3 Pancreatic steatorrhoea
0.000 0.512 0.488
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.512 0.488
K90.1 Tropical sprue
0.000 0.512 0.488
J35.9 Chronic disease of tonsils and adenoids, unspecified
0.000 0.516 0.484
E55 Vitamin D deficiency
0.000 0.524 0.476
M07.38 Other psoriatic arthropathies (Other)
0.475 0.525 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.475 0.525 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.475 0.525 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.475 0.525 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.475 0.525 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.531 0.469
J37.1 Chronic laryngotracheitis
0.000 0.532 0.468
J95-J99 Other diseases of the respiratory system
0.000 0.533 0.467
E65-E68 Obesity and other hyperalimentation
0.000 0.537 0.462
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids
0.000 0.538 0.461
J35.2 Hypertrophy of adenoids
0.000 0.538 0.461
J35.0 Chronic tonsillitis
0.000 0.541 0.458
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.549 0.451
E63 Other nutritional deficiencies
0.000 0.549 0.451
E56 Other vitamin deficiencies
0.000 0.549 0.451
E51 Thiamine deficiency
0.000 0.549 0.451
E50 Vitamin A deficiency
0.000 0.549 0.451
E60 Dietary zinc deficiency
0.000 0.549 0.451
E59 Dietary selenium deficiency
0.000 0.549 0.451
E58 Dietary calcium deficiency
0.000 0.549 0.451
E54 Ascorbic acid deficiency
0.000 0.549 0.451
E52 Niacin deficiency [pellagra]
0.000 0.549 0.451
J01.8 Other acute sinusitis
0.000 0.559 0.441
J01.4 Acute pansinusitis
0.000 0.559 0.441
J01.3 Acute sphenoidal sinusitis
0.000 0.559 0.441
J01.2 Acute ethmoidal sinusitis
0.000 0.559 0.441
J01.1 Acute frontal sinusitis
0.000 0.559 0.441
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.559 0.441
J86.0 Pyothorax with fistula
0.000 0.562 0.438
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.566 0.434
E45 Retarded development following protein-energy malnutrition
0.000 0.566 0.434
E43 Unspecified severe protein-energy malnutrition
0.000 0.566 0.434
E42 Marasmic kwashiorkor
0.000 0.566 0.434
E41 Nutritional marasmus
0.000 0.566 0.434
E40 Kwashiorkor
0.000 0.566 0.434
J39.8 Other specified diseases of upper respiratory tract
0.000 0.576 0.424
J69 Pneumonitis due to solids and liquids
0.000 0.578 0.422
E53 Deficiency of other B group vitamins
0.000 0.587 0.413
E13.8 With unspecified complications
0.000 0.588 0.412
E13.7 With multiple complications
0.000 0.588 0.412
E13.6 With other specified complications
0.000 0.588 0.412
E13.5 With peripheral circulatory complications
0.000 0.588 0.412
E13.4 With neurological complications
0.000 0.588 0.412
E13.3 With ophthalmic complications
0.000 0.588 0.412
E13.2 With renal complications
0.000 0.588 0.412
E13.1 With ketoacidosis
0.000 0.588 0.412
E13.0 With coma
0.000 0.588 0.412
J37.0 Chronic laryngitis
0.000 0.596 0.404
J85.3 Abscess of mediastinum
0.000 0.603 0.397
J85.2 Abscess of lung without pneumonia
0.000 0.603 0.397
J85.1 Abscess of lung with pneumonia
0.000 0.603 0.397
J85.0 Gangrene and necrosis of lung
0.000 0.603 0.397
E27 Other disorders of adrenal gland
0.000 0.603 0.397
J01.0 Acute maxillary sinusitis
0.000 0.603 0.396
J43 Emphysema
0.000 0.606 0.394
J21 Acute bronchiolitis
0.000 0.608 0.392
J34 Other disorders of nose and nasal sinuses
0.000 0.608 0.392
E29 Testicular dysfunction
0.000 0.609 0.391
J02 Acute pharyngitis
0.000 0.612 0.387
J06.8 Other acute upper respiratory infections of multiple sites
0.000 0.614 0.386
J06.0 Acute laryngopharyngitis
0.000 0.614 0.386
E04.8 Other specified non-toxic goitre
0.000 0.619 0.381
E61 Deficiency of other nutrient elements
0.000 0.622 0.378
J62.8 Pneumoconiosis due to other dust containing silica
0.000 0.626 0.374
J62.0 Pneumoconiosis due to talc dust
0.000 0.626 0.374
J63.8 Pneumoconiosis due to other specified inorganic dusts
0.000 0.626 0.374
J63.5 Stannosis
0.000 0.626 0.374
J63.4 Siderosis
0.000 0.626 0.374
J63.3 Graphite fibrosis (of lung)
0.000 0.626 0.374
J63.2 Berylliosis
0.000 0.626 0.374
J63.1 Bauxite fibrosis (of lung)
0.000 0.626 0.374
J63.0 Aluminosis (of lung)
0.000 0.626 0.374
J66.8 Airway disease due to other specific organic dusts
0.000 0.626 0.374
J66.2 Cannabinosis
0.000 0.626 0.374
J66.1 Flax-dresser's disease
0.000 0.626 0.374
J66.0 Byssinosis
0.000 0.626 0.374
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust
0.000 0.626 0.374
J67.8 Hypersensitivity pneumonitis due to other organic dusts
0.000 0.626 0.374
J67.7 Air-conditioner and humidifier lung
0.000 0.626 0.374
J67.6 Maple-bark-stripper's lung
0.000 0.626 0.374
J67.5 Mushroom-worker's lung
0.000 0.626 0.374
J67.4 Maltworker's lung
0.000 0.626 0.374
J67.3 Suberosis
0.000 0.626 0.374
J67.2 Bird fancier's lung
0.000 0.626 0.374
J67.1 Bagassosis
0.000 0.626 0.374
J67.0 Farmer's lung
0.000 0.626 0.374
J68.9 Unspecified respiratory condition due to chemicals, gases, fumes and vapours
0.000 0.626 0.374
J68.8 Other respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.626 0.374
J68.4 Chronic respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.626 0.374
J68.3 Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.626 0.374
J68.2 Upper respiratory inflammation due to chemicals, gases, fumes and vapours, not elsewhere classified
0.000 0.626 0.374
J68.1 Acute pulmonary oedema due to chemicals, gases, fumes and vapours
0.000 0.626 0.374
J68.0 Bronchitis and pneumonitis due to chemicals, gases, fumes and vapours
0.000 0.626 0.374
J70.9 Respiratory conditions due to unspecified external agent
0.000 0.626 0.374
J70.8 Respiratory conditions due to other specified external agents
0.000 0.626 0.374
J70.4 Drug-induced interstitial lung disorder, unspecified
0.000 0.626 0.374
J70.3 Chronic drug-induced interstitial lung disorders
0.000 0.626 0.374
J70.2 Acute drug-induced interstitial lung disorders
0.000 0.626 0.374
J70.1 Chronic and other pulmonary manifestations due to radiation
0.000 0.626 0.374
J70.0 Acute pulmonary manifestations due to radiation
0.000 0.626 0.374
J04.0 Acute laryngitis
0.000 0.627 0.372
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.628 0.372
J04.2 Acute laryngotracheitis
0.000 0.628 0.371
J06.9 Acute upper respiratory infection, unspecified
0.000 0.633 0.367
J05.0 Acute obstructive laryngitis [croup]
0.000 0.633 0.367
E55.9 Vitamin D deficiency, unspecified
0.000 0.633 0.367
E04.0 Non-toxic diffuse goitre
0.000 0.636 0.364
E27.1 Primary adrenocortical insufficiency
0.000 0.638 0.362
L40-L45 Papulosquamous disorders
0.356 0.643 0.000
J20 Acute bronchitis
0.000 0.652 0.348
E04.9 Non-toxic goitre, unspecified
0.000 0.655 0.345
E04.2 Non-toxic multinodular goitre
0.000 0.657 0.343
E55.0 Rickets, active
0.000 0.658 0.342
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.663 0.336
E32 Diseases of thymus
0.000 0.663 0.336
E31 Polyglandular dysfunction
0.000 0.663 0.336
E30 Disorders of puberty, not elsewhere classified
0.000 0.663 0.336
E25 Adrenogenital disorders
0.000 0.663 0.336
E20 Hypoparathyroidism
0.000 0.663 0.336
E04.1 Non-toxic single thyroid nodule
0.000 0.664 0.336
E29.1 Testicular hypofunction
0.000 0.665 0.335
J96 Respiratory failure, not elsewhere classified
0.000 0.665 0.335
J04.1 Acute tracheitis
0.000 0.668 0.332
E67 Other hyperalimentation
0.000 0.668 0.332
E68 Sequelae of hyperalimentation
0.000 0.668 0.332
E65 Localised adiposity
0.000 0.668 0.332
E46 Unspecified protein-energy malnutrition
0.001 0.675 0.324
E50.9 Vitamin A deficiency, unspecified
0.000 0.676 0.324
E50.8 Other manifestations of vitamin A deficiency
0.000 0.676 0.324
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.676 0.324
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.676 0.324
E50.5 Vitamin A deficiency with night blindness
0.000 0.676 0.324
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.676 0.324
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.676 0.324
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.676 0.324
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.676 0.324
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.676 0.324
E51.9 Thiamine deficiency, unspecified
0.000 0.676 0.324
E51.8 Other manifestations of thiamine deficiency
0.000 0.676 0.324
E51.2 Wernicke's encephalopathy
0.000 0.676 0.324
E51.1 Beriberi
0.000 0.676 0.324
E56.9 Vitamin deficiency, unspecified
0.000 0.676 0.324
E56.8 Deficiency of other vitamins
0.000 0.676 0.324
E56.1 Deficiency of vitamin K
0.000 0.676 0.324
E56.0 Deficiency of vitamin E
0.000 0.676 0.324
E63.9 Nutritional deficiency, unspecified
0.000 0.676 0.324
E63.8 Other specified nutritional deficiencies
0.000 0.676 0.324
E63.1 Imbalance of constituents of food intake
0.000 0.676 0.324
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.676 0.324
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.676 0.324
E64.8 Sequelae of other nutritional deficiencies
0.000 0.676 0.324
E64.3 Sequelae of rickets
0.000 0.676 0.324
E64.2 Sequelae of vitamin C deficiency
0.000 0.676 0.324
E64.1 Sequelae of vitamin A deficiency
0.000 0.676 0.324
E64.0 Sequelae of protein-energy malnutrition
0.000 0.676 0.324
J05.1 Acute epiglottitis
0.000 0.678 0.321
E34 Other endocrine disorders
0.000 0.681 0.319
J34.0 Abscess, furuncle and carbuncle of nose
0.000 0.683 0.317
E26 Hyperaldosteronism
0.000 0.684 0.316
E22 Hyperfunction of pituitary gland
0.000 0.684 0.316
E44.1 Mild protein-energy malnutrition
0.000 0.689 0.311
E44.0 Moderate protein-energy malnutrition
0.000 0.689 0.311
E70-E90 Metabolic disorders
0.000 0.690 0.310
M07 Psoriatic and enteropathic arthropathies
0.304 0.692 0.004
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.693 0.307
J99.8 Respiratory disorders in other diseases classified elsewhere
0.000 0.696 0.304
J69.1 Pneumonitis due to oils and essences
0.000 0.697 0.303
E53.9 Vitamin B deficiency, unspecified
0.000 0.704 0.296
E53.1 Pyridoxine deficiency
0.000 0.704 0.296
E53.0 Riboflavin deficiency
0.000 0.704 0.296
J22 Unspecified acute lower respiratory infection
0.000 0.706 0.294
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.708 0.292
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.712 0.287
J90-J94 Other diseases of pleura
0.000 0.714 0.285
E27.5 Adrenomedullary hyperfunction
0.000 0.715 0.285
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.715 0.285
E27.0 Other adrenocortical overactivity
0.000 0.715 0.285
J43.8 Other emphysema
0.000 0.717 0.282
J43.1 Panlobular emphysema
0.000 0.717 0.282
J43.0 MacLeod's syndrome
0.000 0.717 0.282
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.717 0.283
E89.0 Postprocedural hypothyroidism
0.000 0.718 0.282
J21.9 Acute bronchiolitis, unspecified
0.000 0.719 0.281
J21.8 Acute bronchiolitis due to other specified organisms
0.000 0.719 0.281
J21.1 Acute bronchiolitis due to human metapneumovirus
0.000 0.719 0.281
J21.0 Acute bronchiolitis due to respiratory syncytial virus
0.000 0.719 0.281
E28 Ovarian dysfunction
0.000 0.719 0.281
E29.9 Testicular dysfunction, unspecified
0.000 0.719 0.280
E29.8 Other testicular dysfunction
0.000 0.719 0.280
E29.0 Testicular hyperfunction
0.000 0.719 0.280
J02.8 Acute pharyngitis due to other specified organisms
0.000 0.722 0.278
J02.0 Streptococcal pharyngitis
0.000 0.722 0.278
E27.8 Other specified disorders of adrenal gland
0.000 0.725 0.274
E13.9 Without complications
0.001 0.728 0.271
E27.9 Disorder of adrenal gland, unspecified
0.000 0.728 0.272
E61.9 Deficiency of nutrient element, unspecified
0.000 0.729 0.271
E61.8 Deficiency of other specified nutrient elements
0.000 0.729 0.271
E61.7 Deficiency of multiple nutrient elements
0.000 0.729 0.271
E61.6 Vanadium deficiency
0.000 0.729 0.271
E61.5 Molybdenum deficiency
0.000 0.729 0.271
E61.4 Chromium deficiency
0.000 0.729 0.271
E61.3 Manganese deficiency
0.000 0.729 0.271
E61.2 Magnesium deficiency
0.000 0.729 0.271
E61.0 Copper deficiency
0.000 0.729 0.271
J34.3 Hypertrophy of nasal turbinates
0.000 0.730 0.270
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.733 0.267
J99.0 Rheumatoid lung disease
0.000 0.733 0.267
J69.0 Pneumonitis due to food and vomit
0.000 0.733 0.267
L42 Pityriasis rosea
0.266 0.733 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.742 0.258
L44 Other papulosquamous disorders
0.256 0.744 0.000
L41 Parapsoriasis
0.256 0.744 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.256 0.744 0.000
E27.2 Addisonian crisis
0.000 0.745 0.255
J69.8 Pneumonitis due to other solids and liquids
0.000 0.746 0.254
E24 Cushing's syndrome
0.001 0.748 0.252
J43.2 Centrilobular emphysema
0.001 0.750 0.249
J20.8 Acute bronchitis due to other specified organisms
0.000 0.750 0.249
J20.7 Acute bronchitis due to echovirus
0.000 0.750 0.249
J20.6 Acute bronchitis due to rhinovirus
0.000 0.750 0.249
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.750 0.249
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.750 0.249
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.750 0.249
J20.2 Acute bronchitis due to streptococcus
0.000 0.750 0.249
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.750 0.249
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.750 0.249
J95.8 Other postprocedural respiratory disorders
0.000 0.751 0.249
J34.1 Cyst and mucocele of nose and nasal sinus
0.000 0.753 0.247
E20.9 Hypoparathyroidism, unspecified
0.000 0.758 0.241
E20.8 Other hypoparathyroidism
0.000 0.758 0.241
E20.1 Pseudohypoparathyroidism
0.000 0.758 0.241
E20.0 Idiopathic hypoparathyroidism
0.000 0.758 0.241
E25.9 Adrenogenital disorder, unspecified
0.000 0.758 0.241
E25.8 Other adrenogenital disorders
0.000 0.758 0.241
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.758 0.241
E30.9 Disorder of puberty, unspecified
0.000 0.758 0.241
E30.8 Other disorders of puberty
0.000 0.758 0.241
E30.1 Precocious puberty
0.000 0.758 0.241
E30.0 Delayed puberty
0.000 0.758 0.241
E31.9 Polyglandular dysfunction, unspecified
0.000 0.758 0.241
E31.8 Other polyglandular dysfunction
0.000 0.758 0.241
E31.1 Polyglandular hyperfunction
0.000 0.758 0.241
E31.0 Autoimmune polyglandular failure
0.000 0.758 0.241
E32.9 Disease of thymus, unspecified
0.000 0.758 0.241
E32.8 Other diseases of thymus
0.000 0.758 0.241
E32.1 Abscess of thymus
0.000 0.758 0.241
E32.0 Persistent hyperplasia of thymus
0.000 0.758 0.241
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.758 0.241
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.758 0.241
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.758 0.241
J34.2 Deviated nasal septum
0.000 0.759 0.241
J96.9 Respiratory failure, unspecified
0.000 0.760 0.240
J96.1 Chronic respiratory failure
0.000 0.760 0.240
J96.0 Acute respiratory failure
0.000 0.760 0.240
E83 Disorders of mineral metabolism
0.000 0.761 0.239
E67.8 Other specified hyperalimentation
0.000 0.762 0.238
E67.3 Hypervitaminosis D
0.000 0.762 0.238
E67.2 Megavitamin-B6 syndrome
0.000 0.762 0.238
E67.1 Hypercarotenaemia
0.000 0.762 0.238
E67.0 Hypervitaminosis A
0.000 0.762 0.238
J09-J18 Influenza and pneumonia
0.000 0.765 0.235
E34.9 Endocrine disorder, unspecified
0.000 0.770 0.230
E34.8 Other specified endocrine disorders
0.000 0.771 0.229
E34.5 Androgen resistance syndrome
0.000 0.771 0.229
E34.4 Constitutional tall stature
0.000 0.771 0.229
E34.3 Short stature, not elsewhere classified
0.000 0.771 0.229
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.771 0.229
E34.1 Other hypersecretion of intestinal hormones
0.000 0.771 0.229
J91 Pleural effusion in conditions classified elsewhere
0.000 0.771 0.229
E23 Hypofunction and other disorders of pituitary gland
0.000 0.772 0.228
E22.0 Acromegaly and pituitary gigantism
0.000 0.773 0.227
E26.9 Hyperaldosteronism, unspecified
0.000 0.773 0.227
E26.8 Other hyperaldosteronism
0.000 0.773 0.227
E26.1 Secondary hyperaldosteronism
0.000 0.773 0.227
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.773 0.227
E22.8 Other hyperfunction of pituitary gland
0.000 0.773 0.227
E22.1 Hyperprolactinaemia
0.000 0.773 0.227
E74 Other disorders of carbohydrate metabolism
0.000 0.777 0.223
E89.2 Postprocedural hypoparathyroidism
0.000 0.777 0.222
E84 Cystic fibrosis
0.000 0.778 0.222
E79 Disorders of purine and pyrimidine metabolism
0.000 0.778 0.222
E77 Disorders of glycoprotein metabolism
0.000 0.778 0.222
E76 Disorders of glycosaminoglycan metabolism
0.000 0.778 0.222
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.778 0.222
E73 Lactose intolerance
0.000 0.778 0.222
E72 Other disorders of amino-acid metabolism
0.000 0.778 0.222
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.778 0.222
E70 Disorders of aromatic amino-acid metabolism
0.000 0.778 0.222
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.778 0.222
M07.6 Other enteropathic arthropathies
0.218 0.779 0.003
M07.5 Arthropathy in ulcerative colitis
0.218 0.779 0.003
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.218 0.779 0.003
M07.2 Psoriatic spondylitis
0.218 0.779 0.003
M07.1 Arthritis mutilans
0.218 0.779 0.003
M07.0 Distal interphalangeal psoriatic arthropathy
0.218 0.779 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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