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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3095352
log Bayes Factor = 63.9478
Chromosome 6   position 30,805,921  (GRCh37) Explore rs3095352 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.001 0.999
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.004 0.996
L40 Psoriasis
0.988 0.012 0.000
E10.4 With neurological complications
0.000 0.025 0.975
E10.5 With peripheral circulatory complications
0.000 0.026 0.974
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.037 0.963
E10.1 With ketoacidosis
0.000 0.041 0.959
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.052 0.948
L40.0 Psoriasis vulgaris
0.943 0.057 0.000
L40.5 Arthropathic psoriasis
0.934 0.066 0.000
E14 Unspecified diabetes mellitus
0.000 0.072 0.928
M35.0 Sicca syndrome [Sjogren]
0.000 0.086 0.914
E16 Other disorders of pancreatic internal secretion
0.000 0.089 0.911
E10.2 With renal complications
0.000 0.091 0.909
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.092 0.908
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.104 0.896
E07 Other disorders of thyroid
0.000 0.119 0.881
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.120 0.880
E14.3 With ophthalmic complications
0.000 0.122 0.878
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.144 0.856
E16.2 Hypoglycaemia, unspecified
0.000 0.146 0.854
E10.0 With coma
0.000 0.151 0.848
M35 Other systemic involvement of connective tissue
0.000 0.157 0.843
L40.8 Other psoriasis
0.823 0.177 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.188 0.812
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.205 0.795
E10.6 With other specified complications
0.000 0.207 0.793
E14.8 With unspecified complications
0.000 0.210 0.790
E50-E64 Other nutritional deficiencies
0.000 0.227 0.773
M35.3 Polymyalgia rheumatica
0.000 0.230 0.770
M35.1 Other overlap syndromes
0.000 0.241 0.759
L40.3 Pustulosis palmaris et plantaris
0.757 0.243 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.246 0.754
L40.4 Guttate psoriasis
0.749 0.251 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.251 0.749
E14.6 With other specified complications
0.000 0.259 0.741
E10.7 With multiple complications
0.000 0.262 0.738
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.714 0.286 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.288 0.712
L40.2 Acrodermatitis continua
0.708 0.292 0.000
E14.1 With ketoacidosis
0.000 0.293 0.707
M35.2 Behcet's disease
0.000 0.293 0.707
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.295 0.705
E14.2 Withrenal complications
0.000 0.316 0.683
E15 Nondiabetic hypoglycaemic coma
0.000 0.320 0.679
M06 Other rheumatoid arthritis
0.000 0.321 0.679
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.324 0.676
E20-E35 Disorders of other endocrine glands
0.000 0.328 0.672
E14.7 With multiple complications
0.000 0.335 0.665
E14.0 With coma
0.000 0.335 0.665
E05.8 Other thyrotoxicosis
0.000 0.345 0.655
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.347 0.653
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.347 0.653
E16.4 Abnormal secretion of gastrin
0.000 0.347 0.653
E16.3 Increased secretion of glucagon
0.000 0.347 0.653
E16.1 Other hypoglycaemia
0.000 0.351 0.649
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.352 0.648
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.362 0.638
E03.1 Congenital hypothyroidism without goitre
0.000 0.366 0.634
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.367 0.633
E07.1 Dyshormogenetic goitre
0.000 0.368 0.632
E07.0 Hypersecretion of calcitonin
0.000 0.368 0.632
E13 Other specified diabetes mellitus
0.000 0.371 0.628
M35.7 Hypermobility syndrome
0.000 0.374 0.626
E10.8 With unspecified complications
0.000 0.379 0.620
K90 Intestinal malabsorption
0.000 0.382 0.618
E21.3 Hyperparathyroidism, unspecified
0.000 0.385 0.615
E51 Thiamine deficiency
0.000 0.386 0.614
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.396 0.604
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.396 0.604
M35.5 Multifocal fibrosclerosis
0.000 0.396 0.604
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.396 0.604
E53 Deficiency of other B group vitamins
0.000 0.404 0.596
E06 Thyroiditis
0.000 0.406 0.594
E14.5 With peripheral circulatory complications
0.000 0.413 0.587
M06.4 Inflammatory polyarthropathy
0.000 0.422 0.578
E07.8 Other specified disorders of thyroid
0.000 0.423 0.577
E58 Dietary calcium deficiency
0.000 0.427 0.573
E14.4 With neurological complications
0.000 0.435 0.565
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.435 0.565
E56 Other vitamin deficiencies
0.000 0.442 0.558
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.445 0.555
E63 Other nutritional deficiencies
0.000 0.445 0.555
E50 Vitamin A deficiency
0.000 0.445 0.555
E60 Dietary zinc deficiency
0.000 0.445 0.555
E59 Dietary selenium deficiency
0.000 0.445 0.555
E54 Ascorbic acid deficiency
0.000 0.445 0.555
E52 Niacin deficiency [pellagra]
0.000 0.445 0.555
E03.8 Other specified hypothyroidism
0.000 0.450 0.550
E11 Non-insulin-dependent diabetes mellitus
0.000 0.459 0.541
E21.0 Primary hyperparathyroidism
0.000 0.474 0.526
M35.8 Other specified systemic involvement of connective tissue
0.000 0.477 0.523
M06.8 Other specified rheumatoid arthritis
0.000 0.478 0.522
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.478 0.522
E61 Deficiency of other nutrient elements
0.000 0.483 0.517
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E55 Vitamin D deficiency
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E11.9 Without complications
0.000 0.487 0.513
E40-E46 Malnutrition
0.000 0.498 0.502
E51.2 Wernicke's encephalopathy
0.000 0.500 0.500
E31 Polyglandular dysfunction
0.000 0.504 0.496
E22 Hyperfunction of pituitary gland
0.000 0.508 0.492
M06.3 Rheumatoid nodule
0.000 0.513 0.487
M06.2 Rheumatoid bursitis
0.000 0.513 0.487
M06.1 Adult-onset Still's disease
0.000 0.513 0.487
E53.8 Deficiency of other specified B group vitamins
0.000 0.515 0.485
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.518 0.482
E32 Diseases of thymus
0.000 0.518 0.482
E30 Disorders of puberty, not elsewhere classified
0.000 0.518 0.482
M05-M14 Inflammatory polyarthropathies
0.000 0.524 0.476
E29 Testicular dysfunction
0.000 0.524 0.476
M05 Seropositive rheumatoid arthritis
0.000 0.528 0.472
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.529 0.471
E24 Cushing's syndrome
0.000 0.531 0.469
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.538 0.462
E23 Hypofunction and other disorders of pituitary gland
0.000 0.545 0.455
E28 Ovarian dysfunction
0.000 0.548 0.452
E13.8 With unspecified complications
0.000 0.549 0.451
E13.7 With multiple complications
0.000 0.549 0.451
E13.6 With other specified complications
0.000 0.549 0.451
E13.5 With peripheral circulatory complications
0.000 0.549 0.451
E13.4 With neurological complications
0.000 0.549 0.451
E13.2 With renal complications
0.000 0.549 0.451
E13.1 With ketoacidosis
0.000 0.549 0.451
E13.0 With coma
0.000 0.549 0.451
E20 Hypoparathyroidism
0.000 0.551 0.449
E34 Other endocrine disorders
0.000 0.553 0.447
E21.2 Other hyperparathyroidism
0.000 0.555 0.445
K90.3 Pancreatic steatorrhoea
0.000 0.557 0.443
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.557 0.443
K90.1 Tropical sprue
0.000 0.557 0.443
E11.0 With coma
0.000 0.557 0.443
E13.3 With ophthalmic complications
0.000 0.559 0.440
E51.9 Thiamine deficiency, unspecified
0.000 0.559 0.440
E51.8 Other manifestations of thiamine deficiency
0.000 0.559 0.440
E51.1 Beriberi
0.000 0.559 0.440
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.567 0.433
E21.4 Other specified disorders of parathyroid gland
0.000 0.567 0.433
E53.1 Pyridoxine deficiency
0.000 0.572 0.428
E53.0 Riboflavin deficiency
0.000 0.572 0.428
E06.4 Drug-induced thyroiditis
0.000 0.574 0.426
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.574 0.426
E06.0 Acute thyroiditis
0.000 0.574 0.426
K90.9 Intestinal malabsorption, unspecified
0.000 0.575 0.425
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.575 0.425
E04 Other non-toxic goitre
0.000 0.578 0.422
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.580 0.420
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.583 0.417
E25 Adrenogenital disorders
0.000 0.584 0.416
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.585 0.415
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.585 0.415
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.585 0.415
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.585 0.415
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.585 0.415
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.585 0.415
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.585 0.415
E06.5 Other chronic thyroiditis
0.000 0.586 0.414
E14.9 Without complications
0.000 0.587 0.413
E27 Other disorders of adrenal gland
0.000 0.589 0.411
E06.1 Subacute thyroiditis
0.000 0.593 0.407
E56.1 Deficiency of vitamin K
0.000 0.596 0.404
E53.9 Vitamin B deficiency, unspecified
0.000 0.596 0.404
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.598 0.402
E56.9 Vitamin deficiency, unspecified
0.000 0.599 0.400
E56.8 Deficiency of other vitamins
0.000 0.599 0.400
E56.0 Deficiency of vitamin E
0.000 0.599 0.400
E50.9 Vitamin A deficiency, unspecified
0.000 0.602 0.398
E50.8 Other manifestations of vitamin A deficiency
0.000 0.602 0.398
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.602 0.398
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.602 0.398
E50.5 Vitamin A deficiency with night blindness
0.000 0.602 0.398
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.602 0.398
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.602 0.398
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.602 0.398
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.602 0.398
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.602 0.398
E63.9 Nutritional deficiency, unspecified
0.000 0.602 0.398
E63.8 Other specified nutritional deficiencies
0.000 0.602 0.398
E63.1 Imbalance of constituents of food intake
0.000 0.602 0.398
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.602 0.398
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.602 0.398
E64.8 Sequelae of other nutritional deficiencies
0.000 0.602 0.398
E64.3 Sequelae of rickets
0.000 0.602 0.398
E64.2 Sequelae of vitamin C deficiency
0.000 0.602 0.398
E64.1 Sequelae of vitamin A deficiency
0.000 0.602 0.398
E64.0 Sequelae of protein-energy malnutrition
0.000 0.602 0.398
E11.3 With ophthalmic complications
0.000 0.604 0.396
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.606 0.394
E06.9 Thyroiditis, unspecified
0.000 0.607 0.393
E27.1 Primary adrenocortical insufficiency
0.000 0.607 0.393
E06.3 Autoimmune thyroiditis
0.000 0.610 0.390
E11.7 With multiple complications
0.000 0.612 0.388
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.615 0.385
M06.34 Rheumatoid nodule (Hand)
0.000 0.617 0.383
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.620 0.379
E22.1 Hyperprolactinaemia
0.000 0.621 0.379
E11.6 With other specified complications
0.000 0.622 0.377
E11.5 With peripheral circulatory complications
0.000 0.623 0.377
E13.9 Without complications
0.000 0.623 0.377
E61.1 Iron deficiency
0.000 0.623 0.377
K90.8 Other intestinal malabsorption
0.000 0.624 0.376
E65-E68 Obesity and other hyperalimentation
0.000 0.624 0.376
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.625 0.374
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.625 0.374
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.625 0.374
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.625 0.374
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.625 0.374
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.625 0.374
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.625 0.374
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.625 0.374
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.628 0.372
E61.9 Deficiency of nutrient element, unspecified
0.000 0.629 0.370
E61.8 Deficiency of other specified nutrient elements
0.000 0.629 0.370
E61.7 Deficiency of multiple nutrient elements
0.000 0.629 0.370
E61.6 Vanadium deficiency
0.000 0.629 0.370
E61.5 Molybdenum deficiency
0.000 0.629 0.370
E61.4 Chromium deficiency
0.000 0.629 0.370
E61.3 Manganese deficiency
0.000 0.629 0.370
E61.0 Copper deficiency
0.000 0.629 0.370
E31.0 Autoimmune polyglandular failure
0.000 0.630 0.370
E55.0 Rickets, active
0.000 0.631 0.369
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.633 0.366
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.634 0.366
M12 Other specific arthropathies
0.000 0.639 0.361
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.640 0.360
E45 Retarded development following protein-energy malnutrition
0.000 0.640 0.360
E43 Unspecified severe protein-energy malnutrition
0.000 0.640 0.360
E42 Marasmic kwashiorkor
0.000 0.640 0.360
E41 Nutritional marasmus
0.000 0.640 0.360
E40 Kwashiorkor
0.000 0.640 0.360
E31.9 Polyglandular dysfunction, unspecified
0.000 0.644 0.356
E31.8 Other polyglandular dysfunction
0.000 0.644 0.356
E31.1 Polyglandular hyperfunction
0.000 0.644 0.356
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.647 0.352
E22.8 Other hyperfunction of pituitary gland
0.000 0.647 0.352
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.651 0.349
M06.38 Rheumatoid nodule (Other)
0.000 0.651 0.349
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.651 0.349
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.651 0.349
M06.33 Rheumatoid nodule (Forearm)
0.000 0.651 0.349
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.651 0.349
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.651 0.349
M06.18 Adult-onset Still's disease (Other)
0.000 0.651 0.349
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.651 0.349
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.651 0.349
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.651 0.349
M06.14 Adult-onset Still's disease (Hand)
0.000 0.651 0.349
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.651 0.349
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.651 0.349
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.651 0.349
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.651 0.349
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.651 0.349
M06.28 Rheumatoid bursitis (Other)
0.000 0.651 0.349
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.651 0.349
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.651 0.349
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.651 0.349
M06.24 Rheumatoid bursitis (Hand)
0.000 0.651 0.349
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.651 0.349
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.651 0.349
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.651 0.349
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.651 0.349
M05.8 Other seropositive rheumatoid arthritis
0.000 0.651 0.348
E30.9 Disorder of puberty, unspecified
0.000 0.654 0.345
E30.8 Other disorders of puberty
0.000 0.654 0.345
E30.1 Precocious puberty
0.000 0.654 0.345
E30.0 Delayed puberty
0.000 0.654 0.345
E32.9 Disease of thymus, unspecified
0.000 0.654 0.345
E32.8 Other diseases of thymus
0.000 0.654 0.345
E32.1 Abscess of thymus
0.000 0.654 0.345
E32.0 Persistent hyperplasia of thymus
0.000 0.654 0.345
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.654 0.345
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.654 0.345
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.654 0.345
E29.9 Testicular dysfunction, unspecified
0.000 0.655 0.345
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.659 0.341
E29.8 Other testicular dysfunction
0.000 0.659 0.341
E29.0 Testicular hyperfunction
0.000 0.659 0.341
E24.2 Drug-induced Cushing's syndrome
0.000 0.661 0.339
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.661 0.339
E24.9 Cushing's syndrome, unspecified
0.000 0.661 0.339
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.661 0.338
M05.1 Rheumatoid lung disease
0.000 0.661 0.338
M05.0 Felty's syndrome
0.000 0.661 0.338
E04.9 Non-toxic goitre, unspecified
0.000 0.662 0.338
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.662 0.338
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.662 0.338
E24.8 Other Cushing's syndrome
0.000 0.664 0.336
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.664 0.336
E24.3 Ectopic ACTH syndrome
0.000 0.664 0.336
E24.1 Nelson's syndrome
0.000 0.664 0.336
E34.3 Short stature, not elsewhere classified
0.000 0.665 0.334
E04.0 Non-toxic diffuse goitre
0.000 0.669 0.331
E29.1 Testicular hypofunction
0.000 0.669 0.331
E34.9 Endocrine disorder, unspecified
0.000 0.671 0.329
M05.2 Rheumatoid vasculitis
0.000 0.671 0.328
E23.0 Hypopituitarism
0.000 0.672 0.328
E55.9 Vitamin D deficiency, unspecified
0.000 0.672 0.328
M08 Juvenile arthritis
0.000 0.673 0.327
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.673 0.327
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.674 0.326
E23.1 Drug-induced hypopituitarism
0.000 0.674 0.326
E26 Hyperaldosteronism
0.000 0.675 0.324
E23.7 Disorder of pituitary gland, unspecified
0.000 0.676 0.324
E28.9 Ovarian dysfunction, unspecified
0.000 0.676 0.324
E28.8 Other ovarian dysfunction
0.000 0.676 0.324
E28.1 Androgen excess
0.000 0.676 0.324
E28.0 Oestrogen excess
0.000 0.676 0.324
E61.2 Magnesium deficiency
0.000 0.676 0.324
E20.8 Other hypoparathyroidism
0.000 0.678 0.322
E20.1 Pseudohypoparathyroidism
0.000 0.678 0.322
E20.0 Idiopathic hypoparathyroidism
0.000 0.678 0.322
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.678 0.322
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.679 0.320
E34.5 Androgen resistance syndrome
0.000 0.680 0.320
E34.4 Constitutional tall stature
0.000 0.680 0.320
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.680 0.320
E34.1 Other hypersecretion of intestinal hormones
0.000 0.680 0.320
E28.3 Primary ovarian failure
0.000 0.681 0.319
E23.2 Diabetes insipidus
0.000 0.681 0.319
E24.0 Pituitary-dependent Cushing's disease
0.000 0.683 0.316
E22.0 Acromegaly and pituitary gigantism
0.000 0.686 0.314
E11.8 With unspecified complications
0.000 0.687 0.313
M10 Gout
0.000 0.690 0.310
M14 Arthropathies in other diseases classified elsewhere
0.000 0.691 0.309
E23.6 Other disorders of pituitary gland
0.000 0.692 0.307
E34.8 Other specified endocrine disorders
0.000 0.694 0.306
L40-L45 Papulosquamous disorders
0.303 0.697 0.000
E04.8 Other specified non-toxic goitre
0.000 0.697 0.302
E28.2 Polycystic ovarian syndrome
0.000 0.701 0.299
E25.9 Adrenogenital disorder, unspecified
0.000 0.701 0.298
E25.8 Other adrenogenital disorders
0.000 0.701 0.298
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.702 0.298
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.703 0.297
E27.5 Adrenomedullary hyperfunction
0.000 0.705 0.295
E27.0 Other adrenocortical overactivity
0.000 0.705 0.295
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.709 0.291
E20.9 Hypoparathyroidism, unspecified
0.000 0.711 0.289
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.721 0.278
M11 Other crystal arthropathies
0.000 0.722 0.278
M12.3 Palindromic rheumatism
0.000 0.723 0.277
E34.0 Carcinoid syndrome
0.000 0.729 0.271
E67 Other hyperalimentation
0.000 0.730 0.269
E68 Sequelae of hyperalimentation
0.000 0.730 0.269
M10.0 Idiopathic gout
0.000 0.732 0.268
M12.5 Traumatic arthropathy
0.000 0.732 0.267
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.734 0.265
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.740 0.260
M12.4 Intermittent hydrarthrosis
0.000 0.741 0.259
M12.1 Kaschin-Beck disease
0.000 0.741 0.259
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.741 0.259
E44.1 Mild protein-energy malnutrition
0.000 0.742 0.258
E44.0 Moderate protein-energy malnutrition
0.000 0.742 0.258
E11.1 With ketoacidosis
0.000 0.743 0.256
E27.2 Addisonian crisis
0.000 0.747 0.253
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.750 0.250
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.750 0.250
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.750 0.250
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.750 0.250
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.750 0.250
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.750 0.250
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.750 0.250
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.750 0.250
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.750 0.250
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.755 0.245
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.755 0.245
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.755 0.245
M09.0 Juvenile arthritis in psoriasis
0.000 0.755 0.245
M10.07 Idiopathic gout (Ankle and foot)
0.000 0.756 0.244
M12.2 Villonodular synovitis (pigmented)
0.000 0.756 0.243
M05.09 Felty's syndrome (Site unspecified)
0.000 0.757 0.243
M05.08 Felty's syndrome (Other)
0.000 0.757 0.243
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.757 0.243
M05.06 Felty's syndrome (Lower leg)
0.000 0.757 0.243
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.757 0.243
M05.04 Felty's syndrome (Hand)
0.000 0.757 0.243
M05.03 Felty's syndrome (Forearm)
0.000 0.757 0.243
M05.02 Felty's syndrome (Upper arm)
0.000 0.757 0.243
M05.01 Felty's syndrome (Shoulder region)
0.000 0.757 0.243
M05.00 Felty's syndrome (Multiple sites)
0.000 0.757 0.243
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.757 0.243
M05.18 Rheumatoid lung disease (Other)
0.000 0.757 0.243
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.757 0.243
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.757 0.243
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.757 0.243
M05.14 Rheumatoid lung disease (Hand)
0.000 0.757 0.243
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.757 0.243
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.757 0.243
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.757 0.243
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.757 0.243
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.757 0.243
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.757 0.243
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.757 0.243
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.757 0.243
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.757 0.243
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.757 0.243
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.757 0.243
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.757 0.243
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.757 0.243
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.757 0.243
L42 Pityriasis rosea
0.239 0.761 0.000
M05.28 Rheumatoid vasculitis (Other)
0.000 0.764 0.236
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.000 0.764 0.236
M05.26 Rheumatoid vasculitis (Lower leg)
0.000 0.764 0.236
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.000 0.764 0.236
M05.24 Rheumatoid vasculitis (Hand)
0.000 0.764 0.236
M05.23 Rheumatoid vasculitis (Forearm)
0.000 0.764 0.236
M05.22 Rheumatoid vasculitis (Upper arm)
0.000 0.764 0.236
M05.21 Rheumatoid vasculitis (Shoulder region)
0.000 0.764 0.236
M08.9 Juvenile arthritis, unspecified
0.000 0.765 0.235
M08.8 Other juvenile arthritis
0.000 0.765 0.235
M08.4 Pauciarticular juvenile arthritis
0.000 0.765 0.235
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.765 0.235
M08.2 Juvenile arthritis with systemic onset
0.000 0.765 0.235
M08.1 Juvenile ankylosing spondylitis
0.000 0.765 0.235
M05.29 Rheumatoid vasculitis (Site unspecified)
0.000 0.765 0.234
E26.8 Other hyperaldosteronism
0.000 0.767 0.233
E26.1 Secondary hyperaldosteronism
0.000 0.767 0.233
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.767 0.232
M05.20 Rheumatoid vasculitis (Multiple sites)
0.000 0.773 0.227
M14.2 Diabetic arthropathy
0.000 0.773 0.226
M12.39 Palindromic rheumatism (Site unspecified)
0.000 0.774 0.226
M10.4 Other secondary gout
0.000 0.777 0.222
M10.3 Gout due to impairment of renal function
0.000 0.777 0.222
M10.2 Drug-induced gout
0.000 0.777 0.222
M10.1 Lead-induced gout
0.000 0.777 0.222
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.778 0.222
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.778 0.222
M14.4 Arthropathy in amyloidosis
0.000 0.778 0.222
M14.3 Lipoid dermatoarthritis
0.000 0.778 0.222
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.778 0.222
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.778 0.222
M08.0 Juvenile rheumatoid arthritis
0.000 0.779 0.221
L41 Parapsoriasis
0.217 0.782 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.217 0.782 0.000
L44 Other papulosquamous disorders
0.217 0.783 0.000
M10.06 Idiopathic gout (Lower leg)
0.000 0.797 0.203
E27.9 Disorder of adrenal gland, unspecified
0.000 0.797 0.203
E11.2 With renal complications
0.000 0.797 0.203
M12.57 Traumatic arthropathy (Ankle and foot)
0.000 0.799 0.201
E26.9 Hyperaldosteronism, unspecified
0.001 0.799 0.200
M11.1 Familial chondrocalcinosis
0.000 0.800 0.199
M11.0 Hydroxyapatite deposition disease
0.000 0.800 0.199
M12.38 Palindromic rheumatism (Other)
0.000 0.801 0.199
M12.37 Palindromic rheumatism (Ankle and foot)
0.000 0.801 0.199
M12.36 Palindromic rheumatism (Lower leg)
0.000 0.801 0.199
M12.35 Palindromic rheumatism (Pelvic region and thigh)
0.000 0.801 0.199
M12.34 Palindromic rheumatism (Hand)
0.000 0.801 0.199
M12.33 Palindromic rheumatism (Forearm)
0.000 0.801 0.199
M12.32 Palindromic rheumatism (Upper arm)
0.000 0.801 0.199
M12.31 Palindromic rheumatism (Shoulder region)
0.000 0.801 0.199
M12.88 Other specific arthropathies, not elsewhere classified (Other)
0.000 0.803 0.197
E67.8 Other specified hyperalimentation
0.000 0.806 0.193
E67.3 Hypervitaminosis D
0.000 0.806 0.193
E67.2 Megavitamin-B6 syndrome
0.000 0.806 0.193
E67.1 Hypercarotenaemia
0.000 0.806 0.193
E67.0 Hypervitaminosis A
0.000 0.806 0.193
M10.08 Idiopathic gout (Other)
0.000 0.808 0.192
M10.05 Idiopathic gout (Pelvic region and thigh)
0.000 0.808 0.192

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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