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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3096674
log Bayes Factor = 85.1077
Chromosome 6   position 32,238,219  (GRCh37) Explore rs3096674 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
G50-G59 Nerve, nerve root and plexus disorders
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
H36.0 Diabetic retinopathy
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
L40-L45 Papulosquamous disorders
1.000 0.000 0.000
G56 Mononeuropathies of upper limb
1.000 0.000 0.000
H36 Retinal disorders in diseases classified elsewhere
1.000 0.000 0.000
G56.0 Carpal tunnel syndrome
1.000 0.000 0.000
E27 Other disorders of adrenal gland
1.000 0.000 0.000
E10.1 With ketoacidosis
1.000 0.000 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.001 0.999
E27.1 Primary adrenocortical insufficiency
0.999 0.001 0.000
E03 Other hypothyroidism
0.999 0.001 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.998 0.002 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.998 0.002 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.998 0.002 0.000
E03.9 Hypothyroidism, unspecified
0.998 0.002 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.997 0.003 0.000
Chapter VII Diseases of the eye and adnexa
0.997 0.003 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.996 0.004 0.000
E11 Non-insulin-dependent diabetes mellitus
0.996 0.004 0.000
E16 Other disorders of pancreatic internal secretion
0.996 0.004 0.000
D60-D64 Aplastic and other anaemias
0.996 0.004 0.000
E16.2 Hypoglycaemia, unspecified
0.995 0.005 0.000
E14 Unspecified diabetes mellitus
0.995 0.005 0.000
G51 Facial nerve disorders
0.994 0.006 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.007 0.993
M06 Other rheumatoid arthritis
0.001 0.007 0.992
D64 Other anaemias
0.992 0.008 0.000
D64.9 Anaemia, unspecified
0.989 0.011 0.000
H34 Retinal vascular occlusions
0.987 0.013 0.000
L50-L54 Urticaria and erythema
0.984 0.016 0.000
E14.3 With ophthalmic complications
0.983 0.017 0.000
E11.3 With ophthalmic complications
0.978 0.022 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.977 0.023 0.000
Chapter II Neoplasms
0.977 0.023 0.000
G51.0 Bell's palsy
0.976 0.024 0.000
G40-G47 Episodic and paroxysmal disorders
0.974 0.026 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.973 0.027 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.973 0.027 0.000
M20.1 Hallux valgus (acquired)
0.000 0.028 0.972
Chapter I Certain infectious and parasitic diseases
0.971 0.029 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.971 0.029 0.000
C85.1 B-cell lymphoma, unspecified
0.971 0.029 0.000
H34.8 Other retinal vascular occlusions
0.970 0.030 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.964 0.036 0.000
E10.2 With renal complications
0.963 0.037 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.962 0.038 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.958 0.042 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.958 0.042 0.000
D70 Agranulocytosis
0.957 0.043 0.000
C91 Lymphoid leukaemia
0.956 0.044 0.000
M06.3 Rheumatoid nodule
0.000 0.047 0.953
H33 Retinal detachments and breaks
0.951 0.049 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.950 0.050 0.000
L10-L14 Bullous disorders
0.949 0.051 0.000
L52 Erythema nodosum
0.949 0.051 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.053 0.947
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.947 0.053 0.000
C83.3 Large cell (diffuse)
0.945 0.055 0.000
H33.3 Retinal breaks without detachment
0.942 0.058 0.000
M05-M14 Inflammatory polyarthropathies
0.109 0.059 0.832
G62 Other polyneuropathies
0.938 0.062 0.000
E11.1 With ketoacidosis
0.936 0.064 0.000
G62.9 Polyneuropathy, unspecified
0.933 0.067 0.000
E21.3 Hyperparathyroidism, unspecified
0.930 0.070 0.000
E11.2 With renal complications
0.929 0.071 0.000
Q60-Q64 Congenital malformations of the urinary system
0.926 0.074 0.000
D61 Other aplastic anaemias
0.924 0.076 0.000
E06 Thyroiditis
0.918 0.082 0.000
L13 Other bullous disorders
0.915 0.085 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.086 0.914
N04 Nephrotic syndrome
0.914 0.086 0.000
N04.9 Unspecified
0.913 0.087 0.000
N00-N08 Glomerular diseases
0.913 0.087 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.909 0.091 0.000
D80-D89 Certain disorders involving the immune mechanism
0.909 0.091 0.000
C91.1 Chronic lymphocytic leukaemia
0.909 0.091 0.000
Q43 Other congenital malformations of intestine
0.908 0.092 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.908 0.092 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.906 0.094 0.000
G51.9 Disorder of facial nerve, unspecified
0.901 0.099 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.901 0.099 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.899 0.101 0.000
E28 Ovarian dysfunction
0.898 0.102 0.000
M05 Seropositive rheumatoid arthritis
0.049 0.103 0.849
B35-B49 Mycoses
0.894 0.106 0.000
L13.0 Dermatitis herpetiformis
0.891 0.109 0.000
E07 Other disorders of thyroid
0.889 0.111 0.000
C81 Hodgkin's disease
0.888 0.112 0.000
L53 Other erythematous conditions
0.885 0.115 0.000
C04 Malignant neoplasm of floor of mouth
0.885 0.115 0.000
N05 Unspecified nephritic syndrome
0.882 0.118 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.880 0.120 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.005 0.121 0.873
B37 Candidiasis
0.878 0.122 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.127 0.872
Q60 Renal agenesis and other reduction defects of kidney
0.871 0.129 0.000
B15-B19 Viral hepatitis
0.868 0.132 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.868 0.132 0.000
E10.4 With neurological complications
0.867 0.133 0.000
B37.8 Candidiasis of other sites
0.867 0.133 0.000
D55-D59 Haemolytic anaemias
0.865 0.135 0.000
E06.3 Autoimmune thyroiditis
0.865 0.135 0.000
D61.9 Aplastic anaemia, unspecified
0.862 0.138 0.000
E27.8 Other specified disorders of adrenal gland
0.860 0.140 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.859 0.141 0.000
L20-L30 Dermatitis and eczema
0.855 0.145 0.000
E50-E64 Other nutritional deficiencies
0.853 0.147 0.000
C07 Malignant neoplasm of parotid gland
0.847 0.153 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.001 0.155 0.844
H34.2 Other retinal artery occlusions
0.844 0.156 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.844 0.156 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.844 0.156 0.000
Chapter VIII Diseases of the ear and mastoid process
0.843 0.157 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.840 0.160 0.000
G51.3 Clonic hemifacial spasm
0.839 0.161 0.000
E10.7 With multiple complications
0.835 0.165 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.834 0.166 0.000
M06.4 Inflammatory polyarthropathy
0.001 0.167 0.833
B07 Viral warts
0.833 0.167 0.000
E07.8 Other specified disorders of thyroid
0.832 0.167 0.000
N40 Hyperplasia of prostate
0.000 0.168 0.832
G56.1 Other lesions of median nerve
0.832 0.168 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.832 0.168 0.000
E28.2 Polycystic ovarian syndrome
0.830 0.170 0.000
C91.9 Lymphoid leukaemia, unspecified
0.829 0.171 0.000
H30 Chorioretinal inflammation
0.828 0.171 0.000
D50-D53 Nutritional anaemias
0.828 0.172 0.000
G56.4 Causalgia
0.828 0.172 0.000
C84.5 Other and unspecified T-cell lymphomas
0.828 0.172 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.172 0.828
E14.8 With unspecified complications
0.827 0.173 0.000
Q00-Q07 Congenital malformations of the nervous system
0.826 0.174 0.000
N05.2 Diffuse membranous glomerulonephritis
0.825 0.175 0.000
B25-B34 Other viral diseases
0.820 0.180 0.000
E27.9 Disorder of adrenal gland, unspecified
0.819 0.180 0.000
E10.0 With coma
0.819 0.181 0.000
D73 Diseases of spleen
0.817 0.183 0.000
G30-G32 Other degenerative diseases of the nervous system
0.816 0.184 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.814 0.186 0.000
E10.8 With unspecified complications
0.811 0.189 0.000
L40.0 Psoriasis vulgaris
0.811 0.189 0.000
H60-H62 Diseases of external ear
0.809 0.191 0.000
G20-G26 Extrapyramidal and movement disorders
0.806 0.194 0.000
Q50-Q56 Congenital malformations of genital organs
0.805 0.195 0.000
E31 Polyglandular dysfunction
0.804 0.196 0.000
L44 Other papulosquamous disorders
0.803 0.197 0.000
L40.3 Pustulosis palmaris et plantaris
0.802 0.198 0.000
C12 Malignant neoplasm of pyriform sinus
0.800 0.200 0.000
C13 Malignant neoplasm of hypopharynx
0.799 0.201 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.203 0.797
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.203 0.797
G59 Mononeuropathy in diseases classified elsewhere
0.795 0.205 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.795 0.205 0.000
G40 Epilepsy
0.794 0.206 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.207 0.793
H61 Other disorders of external ear
0.792 0.208 0.000
C02.9 Tongue, unspecified
0.790 0.210 0.000
M20 Acquired deformities of fingers and toes
0.000 0.210 0.790
E14.1 With ketoacidosis
0.790 0.210 0.000
D72 Other disorders of white blood cells
0.789 0.211 0.000
H61.0 Perichondritis of external ear
0.785 0.215 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.215 0.785
L27 Dermatitis due to substances taken internally
0.784 0.216 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.784 0.216 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.783 0.217 0.000
Q60.2 Renal agenesis, unspecified
0.783 0.217 0.000
C51-C58 Malignant neoplasms of female genital organs
0.783 0.217 0.000
C04.9 Floor of mouth, unspecified
0.783 0.217 0.000
H43-H45 Disorders of vitreous body and globe
0.782 0.218 0.000
L53.9 Erythematous condition, unspecified
0.782 0.218 0.000
G45.3 Amaurosis fugax
0.781 0.219 0.000
L53.0 Toxic erythema
0.780 0.219 0.000
L40.1 Generalised pustular psoriasis
0.779 0.221 0.000
E14.5 With peripheral circulatory complications
0.779 0.221 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.775 0.225 0.000
H33.4 Traction detachment of retina
0.775 0.225 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.773 0.227 0.000
B37.9 Candidiasis, unspecified
0.773 0.227 0.000
N05.1 Focal and segmental glomerular lesions
0.772 0.228 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.771 0.228 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.770 0.229 0.001
G24 Dystonia
0.770 0.230 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.770 0.230 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.768 0.232 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.768 0.232 0.000
C56 Malignant neoplasm of ovary
0.766 0.234 0.000
E24 Cushing's syndrome
0.764 0.236 0.000
E27.2 Addisonian crisis
0.764 0.236 0.000
C83.1 Small cleaved cell (diffuse)
0.762 0.238 0.000
E70-E90 Metabolic disorders
0.762 0.238 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.239 0.761
E11.9 Without complications
0.760 0.240 0.000
Q60.0 Renal agenesis, unilateral
0.760 0.240 0.000
D59 Acquired haemolytic anaemia
0.759 0.241 0.000
E11.5 With peripheral circulatory complications
0.759 0.241 0.000
E11.8 With unspecified complications
0.758 0.242 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.757 0.243 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.756 0.244 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.244 0.755
C88 Malignant immunoproliferative diseases
0.753 0.246 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.752 0.248 0.000
H46 Optic neuritis
0.750 0.250 0.000
C04.0 Anterior floor of mouth
0.750 0.250 0.000
B00 Herpesviral [herpes simplex] infections
0.750 0.250 0.000
D86 Sarcoidosis
0.750 0.250 0.000
L28 Lichen simplex chronicus and prurigo
0.750 0.250 0.000
E14.2 Withrenal complications
0.749 0.251 0.000
N04.2 Diffuse membranous glomerulonephritis
0.748 0.252 0.000
E53 Deficiency of other B group vitamins
0.745 0.255 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.745 0.255 0.000
E21.2 Other hyperparathyroidism
0.745 0.255 0.000
C81.1 Nodular sclerosis
0.744 0.256 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.257 0.743
E10.5 With peripheral circulatory complications
0.743 0.257 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.742 0.258 0.000
C83.7 Burkitt's tumour
0.742 0.258 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.740 0.260 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.740 0.260 0.000
E14.4 With neurological complications
0.740 0.260 0.000
B18 Chronic viral hepatitis
0.738 0.262 0.000
H80-H83 Diseases of inner ear
0.738 0.262 0.000
E89.0 Postprocedural hypothyroidism
0.738 0.262 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.736 0.264 0.001
C02.3 Anterior two-thirds of tongue, part unspecified
0.736 0.264 0.000
H05 Disorders of orbit
0.736 0.264 0.000
L51 Erythema multiforme
0.735 0.265 0.000
G62.1 Alcoholic polyneuropathy
0.735 0.265 0.000
E10.6 With other specified complications
0.734 0.266 0.000
Q74 Other congenital malformations of limb(s)
0.734 0.266 0.000
Q39 Congenital malformations of oesophagus
0.734 0.266 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.733 0.266 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.732 0.268 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.268 0.732
C95 Leukaemia of unspecified cell type
0.729 0.271 0.000
D64.8 Other specified anaemias
0.729 0.271 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.729 0.271 0.000
C81.2 Mixed cellularity
0.726 0.274 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.724 0.275 0.000
G58 Other mononeuropathies
0.724 0.276 0.000
Q43.3 Congenital malformations of intestinal fixation
0.724 0.276 0.000
Q76 Congenital malformations of spine and bony thorax
0.724 0.276 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.723 0.277 0.000
B16 Acute hepatitis B
0.723 0.277 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.722 0.278 0.000
G45.0 Vertebro-basilar artery syndrome
0.722 0.278 0.000
D73.5 Infarction of spleen
0.722 0.278 0.000
B17 Other acute viral hepatitis
0.721 0.279 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.720 0.280 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.281 0.719
E16.1 Other hypoglycaemia
0.718 0.282 0.000
H43 Disorders of vitreous body
0.718 0.282 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.717 0.283 0.000
E32 Diseases of thymus
0.717 0.283 0.000
E30 Disorders of puberty, not elsewhere classified
0.717 0.283 0.000
E25 Adrenogenital disorders
0.717 0.283 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.717 0.283 0.000
L41 Parapsoriasis
0.717 0.283 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.717 0.283 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.717 0.283 0.000
E27.5 Adrenomedullary hyperfunction
0.717 0.283 0.000
E27.0 Other adrenocortical overactivity
0.717 0.283 0.000
L50 Urticaria
0.716 0.283 0.000
E03.5 Myxoedema coma
0.716 0.284 0.000
E03.4 Atrophy of thyroid (acquired)
0.716 0.284 0.000
E03.3 Postinfectious hypothyroidism
0.716 0.284 0.000
E03.1 Congenital hypothyroidism without goitre
0.716 0.284 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.716 0.284 0.000
D80 Immunodeficiency with predominantly antibody defects
0.716 0.284 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.715 0.284 0.000
C94 Other leukaemias of specified cell type
0.715 0.284 0.000
C93 Monocytic leukaemia
0.715 0.284 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.715 0.285 0.000
C85.0 Lymphosarcoma
0.715 0.285 0.000
E15 Nondiabetic hypoglycaemic coma
0.715 0.285 0.000
Q35-Q37 Cleft lip and cleft palate
0.715 0.285 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.715 0.285 0.000
E11.7 With multiple complications
0.714 0.286 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.714 0.286 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.714 0.286 0.000
E16.4 Abnormal secretion of gastrin
0.714 0.286 0.000
E16.3 Increased secretion of glucagon
0.714 0.286 0.000
N05.8 Other
0.714 0.286 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.714 0.286 0.000
E14.7 With multiple complications
0.713 0.286 0.000
E14.0 With coma
0.713 0.286 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.713 0.287 0.000
G51.4 Facial myokymia
0.713 0.287 0.000
G51.2 Melkersson's syndrome
0.713 0.287 0.000
G51.1 Geniculate ganglionitis
0.713 0.287 0.000
Q43.0 Meckel's diverticulum
0.712 0.288 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.712 0.288 0.000
M06.8 Other specified rheumatoid arthritis
0.001 0.288 0.711
M06.2 Rheumatoid bursitis
0.001 0.288 0.711
M06.1 Adult-onset Still's disease
0.001 0.288 0.711
N04.1 Focal and segmental glomerular lesions
0.712 0.288 0.000
H06.2 Dysthyroid exophthalmos
0.712 0.288 0.000
D64.4 Congenital dyserythropoietic anaemia
0.711 0.289 0.000
D64.3 Other sideroblastic anaemias
0.711 0.289 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.711 0.289 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.711 0.289 0.000
D64.0 Hereditary sideroblastic anaemia
0.711 0.289 0.000
C91.5 Adult T-cell leukaemia
0.710 0.289 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.710 0.290 0.000
A63.0 Anogenital (venereal) warts
0.710 0.290 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.709 0.291 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.709 0.291 0.000
Q43.1 Hirschsprung's disease
0.708 0.291 0.000
H34.0 Transient retinal artery occlusion
0.708 0.292 0.000
Q44.6 Cystic disease of liver
0.707 0.293 0.000
E14.6 With other specified complications
0.707 0.293 0.000
H34.9 Retinal vascular occlusion, unspecified
0.707 0.293 0.000
G24.5 Blepharospasm
0.707 0.293 0.000
L54 Erythema in diseases classified elsewhere
0.706 0.294 0.000
H30.9 Chorioretinal inflammation, unspecified
0.706 0.294 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.706 0.294 0.000
H34.1 Central retinal artery occlusion
0.705 0.295 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.704 0.296 0.000
Q64 Other congenital malformations of urinary system
0.703 0.297 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.297 0.703
D73.1 Hypersplenism
0.703 0.297 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.702 0.298 0.000
C34 Malignant neoplasm of bronchus and lung
0.702 0.298 0.000
E14.9 Without complications
0.702 0.298 0.000
D72.8 Other specified disorders of white blood cells
0.702 0.298 0.000
E88 Other metabolic disorders
0.701 0.299 0.000
L11 Other acantholytic disorders
0.701 0.299 0.000
D74 Methaemoglobinaemia
0.700 0.300 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.700 0.300 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.700 0.300 0.000
C03 Malignant neoplasm of gum
0.699 0.300 0.000
B34 Viral infection of unspecified site
0.699 0.300 0.000
H05.2 Exophthalmic conditions
0.699 0.301 0.000
D86.3 Sarcoidosis of skin
0.699 0.301 0.000
A80-A89 Viral infections of the central nervous system
0.699 0.301 0.000
B37.7 Candidal septicaemia
0.699 0.301 0.000
B02 Zoster [herpes zoster]
0.698 0.302 0.000
E34 Other endocrine disorders
0.698 0.302 0.000
D82 Immunodeficiency associated with other major defects
0.697 0.302 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.697 0.302 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.696 0.303 0.000
A75-A79 Rickettsioses
0.696 0.303 0.000
A70-A74 Other diseases caused by chlamydiae
0.696 0.303 0.000
A20-A28 Certain zoonotic bacterial diseases
0.696 0.303 0.000
G11 Hereditary ataxia
0.696 0.304 0.000
L10 Pemphigus
0.696 0.304 0.000
D61.0 Constitutional aplastic anaemia
0.696 0.304 0.000
G70-G73 Diseases of myoneural junction and muscle
0.696 0.304 0.000
H33.1 Retinoschisis and retinal cysts
0.693 0.307 0.000
C86 Other specified types of T/NK-cell lymphoma
0.693 0.307 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.691 0.308 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.691 0.309 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.691 0.309 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.003 0.310 0.687
Q03 Congenital hydrocephalus
0.690 0.310 0.000
Q61 Cystic kidney disease
0.689 0.311 0.000
G00 Bacterial meningitis, not elsewhere classified
0.689 0.311 0.000
E20 Hypoparathyroidism
0.688 0.312 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.688 0.312 0.000
G24.9 Dystonia, unspecified
0.688 0.312 0.000
E51 Thiamine deficiency
0.687 0.313 0.000
C83.6 Undifferentiated (diffuse)
0.687 0.313 0.000
C83.5 Lymphoblastic (diffuse)
0.687 0.313 0.000
C83.4 Immunoblastic (diffuse)
0.687 0.313 0.000
C83.2 Mixed small and large cell (diffuse)
0.687 0.313 0.000
G31.8 Other specified degenerative diseases of nervous system
0.687 0.313 0.000
E21.4 Other specified disorders of parathyroid gland
0.687 0.313 0.000
B37.1 Pulmonary candidiasis
0.686 0.314 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.686 0.314 0.000
C91.7 Other lymphoid leukaemia
0.686 0.314 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.686 0.314 0.000
C91.3 Prolymphocytic leukaemia
0.686 0.314 0.000
C91.2 Subacute lymphocytic leukaemia
0.686 0.314 0.000
B36 Other superficial mycoses
0.685 0.314 0.000
B65-B83 Helminthiases
0.685 0.315 0.000
H33.0 Retinal detachment with retinal break
0.685 0.315 0.000
A15-A19 Tuberculosis
0.684 0.316 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.316 0.683
M06.38 Rheumatoid nodule (Other)
0.000 0.316 0.683
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.316 0.683
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.316 0.683
M06.33 Rheumatoid nodule (Forearm)
0.000 0.316 0.683
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.316 0.683
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.316 0.683
Q80-Q89 Other congenital malformations
0.684 0.316 0.000
Q21 Congenital malformations of cardiac septa
0.683 0.317 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.683 0.317 0.000
C05 Malignant neoplasm of palate
0.683 0.317 0.000
G64 Other disorders of peripheral nervous system
0.681 0.319 0.000
G52 Disorders of other cranial nerves
0.681 0.319 0.000
L14 Bullous disorders in diseases classified elsewhere
0.680 0.320 0.000
D51 Vitamin B12 deficiency anaemia
0.679 0.321 0.000
E06.5 Other chronic thyroiditis
0.677 0.323 0.000
B25 Cytomegaloviral disease
0.677 0.323 0.000
E53.8 Deficiency of other specified B group vitamins
0.677 0.323 0.000
E22 Hyperfunction of pituitary gland
0.677 0.323 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.078 0.325 0.596
M08 Juvenile arthritis
0.078 0.325 0.596
D61.1 Drug-induced aplastic anaemia
0.674 0.326 0.000
L20 Atopic dermatitis
0.673 0.327 0.000
G62.2 Polyneuropathy due to other toxic agents
0.673 0.327 0.000
C38.4 Pleura
0.673 0.327 0.000
C84.4 Peripheral T-cell lymphoma
0.671 0.329 0.000
A65-A69 Other spirochaetal diseases
0.670 0.330 0.000
Q40 Other congenital malformations of upper alimentary tract
0.670 0.330 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.670 0.330 0.000
C81.9 Hodgkin's disease, unspecified
0.668 0.332 0.000
Q45 Other congenital malformations of digestive system
0.668 0.332 0.000
L25 Unspecified contact dermatitis
0.667 0.333 0.000
B94 Sequelae of other and unspecified infectious and parasitic diseases
0.665 0.335 0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.664 0.335 0.000
C02.1 Border of tongue
0.664 0.336 0.000
E31.0 Autoimmune polyglandular failure
0.664 0.336 0.000
H47.2 Optic atrophy
0.663 0.337 0.000
D61.8 Other specified aplastic anaemias
0.662 0.338 0.000
D61.3 Idiopathic aplastic anaemia
0.662 0.338 0.000
D61.2 Aplastic anaemia due to other external agents
0.662 0.338 0.000
L44.0 Pityriasis rubra pilaris
0.662 0.338 0.000
M12 Other specific arthropathies
0.075 0.338 0.587
G46 Vascular syndromes of brain in cerebrovascular diseases
0.662 0.338 0.000
C11 Malignant neoplasm of nasopharynx
0.661 0.338 0.000
H83 Other diseases of inner ear
0.661 0.339 0.000
D83 Common variable immunodeficiency
0.661 0.339 0.000
N03 Chronic nephritic syndrome
0.661 0.339 0.000
L28.0 Lichen simplex chronicus
0.661 0.339 0.000
G56.8 Other mononeuropathies of upper limb
0.660 0.340 0.000
Q44.5 Other congenital malformations of bile ducts
0.659 0.340 0.000
E06.4 Drug-induced thyroiditis
0.658 0.342 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.658 0.342 0.000
E06.1 Subacute thyroiditis
0.658 0.342 0.000
E06.0 Acute thyroiditis
0.658 0.342 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.658 0.342 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.658 0.342 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.657 0.343 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.657 0.343 0.000
C10 Malignant neoplasm of oropharynx
0.657 0.343 0.000
Q68 Other congenital musculoskeletal deformities
0.656 0.344 0.000
L13.9 Bullous disorder, unspecified
0.656 0.344 0.000
L13.8 Other specified bullous disorders
0.656 0.344 0.000
L13.1 Subcorneal pustular dermatitis
0.656 0.344 0.000
N04.8 Other
0.655 0.345 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.655 0.345 0.000
N04.6 Dense deposit disease
0.655 0.345 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.655 0.345 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.655 0.345 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.655 0.345 0.000
N04.0 Minor glomerular abnormality
0.655 0.345 0.000
H43.1 Vitreous haemorrhage
0.655 0.345 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.655 0.345 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.654 0.346 0.000
N06 Isolated proteinuria with specified morphological lesion
0.654 0.346 0.000
N01 Rapidly progressive nephritic syndrome
0.654 0.346 0.000
N00 Acute nephritic syndrome
0.654 0.346 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.654 0.346 0.000
C91.0 Acute lymphoblastic leukaemia
0.653 0.346 0.000
D69 Purpura and other haemorrhagic conditions
0.653 0.347 0.000
H61.1 Non-infective disorders of pinna
0.653 0.347 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.652 0.348 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.652 0.348 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.652 0.348 0.000
C84.3 Lymphoepithelioid lymphoma
0.652 0.348 0.000
C84.2 T-zone lymphoma
0.652 0.348 0.000
C84.1 Sezary's diease
0.652 0.348 0.000
D81 Combined immunodeficiencies
0.651 0.348 0.000
M20.4 Other hammer toe(s) (acquired)
0.000 0.349 0.651
Q43.7 Persistent cloaca
0.651 0.349 0.000
Q43.6 Congenital fistula of rectum and anus
0.651 0.349 0.000
Q43.5 Ectopic anus
0.651 0.349 0.000
Q43.4 Duplication of intestine
0.651 0.349 0.000
Q43.2 Other congenital functional disorders of colon
0.651 0.349 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.651 0.349 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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