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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3096691
log Bayes Factor = 52.4329
Chromosome 6   position 32,194,854  (GRCh37) Explore rs3096691 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
0.000 0.000 1.000
E50-E64 Other nutritional deficiencies
0.000 0.000 1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E27.1 Primary adrenocortical insufficiency
0.000 0.001 0.999
D86.9 Sarcoidosis, unspecified
0.000 0.001 0.999
M35.3 Polymyalgia rheumatica
0.000 0.001 0.999
D86 Sarcoidosis
0.000 0.001 0.999
Chapter I Certain infectious and parasitic diseases
0.000 0.001 0.999
D80-D89 Certain disorders involving the immune mechanism
0.000 0.001 0.999
M05 Seropositive rheumatoid arthritis
0.000 0.001 0.999
G35 Multiple sclerosis
0.000 0.001 0.999
J40-J47 Chronic lower respiratory diseases
0.000 0.002 0.998
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.002 0.998
E27 Other disorders of adrenal gland
0.000 0.002 0.998
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.002 0.998
M35 Other systemic involvement of connective tissue
0.000 0.002 0.998
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.002 0.998
K90 Intestinal malabsorption
0.000 0.002 0.998
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.003 0.997
M20-M25 Other joint disorders
0.000 0.003 0.997
B25-B34 Other viral diseases
0.000 0.004 0.996
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.004 0.996
K51 Ulcerative colitis
0.000 0.004 0.996
E20-E35 Disorders of other endocrine glands
0.000 0.004 0.996
E53 Deficiency of other B group vitamins
0.000 0.004 0.996
J47 Bronchiectasis
0.000 0.004 0.996
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.004 0.996
E55 Vitamin D deficiency
0.000 0.006 0.994
Chapter XI Diseases of the digestive system
0.000 0.008 0.992
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.008 0.992
K90-K93 Other diseases of the digestive system
0.000 0.008 0.992
K50-K52 Noninfective enteritis and colitis
0.000 0.008 0.992
E55.9 Vitamin D deficiency, unspecified
0.000 0.010 0.990
A63.0 Anogenital (venereal) warts
0.000 0.010 0.990
E53.8 Deficiency of other specified B group vitamins
0.000 0.011 0.989
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.015 0.985
B25 Cytomegaloviral disease
0.000 0.018 0.982
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.018 0.982
J20-J22 Other acute lower respiratory infections
0.000 0.020 0.980
B35-B49 Mycoses
0.000 0.020 0.980
D50-D53 Nutritional anaemias
0.000 0.024 0.976
M34 Systemic sclerosis
0.000 0.027 0.973
B25.9 Cytomegaloviral disease, unspecified
0.000 0.028 0.972
J84 Other interstitial pulmonary diseases
0.000 0.029 0.971
J33.0 Polyp of nasal cavity
0.000 0.030 0.970
J33 Nasal polyp
0.000 0.033 0.967
J30-J39 Other diseases of upper respiratory tract
0.000 0.035 0.965
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.037 0.963
B37 Candidiasis
0.000 0.037 0.963
K51.8 Other ulcerative colitis
0.000 0.043 0.957
E10-E14 Diabetes mellitus
0.000 0.045 0.955
E10.9 Without complications
0.000 0.046 0.954
E10 Insulin-dependent diabetes mellitus
0.000 0.047 0.953
D50 Iron deficiency anaemia
0.000 0.051 0.949
J45 Asthma
0.000 0.051 0.949
B34 Viral infection of unspecified site
0.000 0.054 0.946
M31 Other necrotising vasculopathies
0.000 0.056 0.944
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.057 0.943
J45.9 Asthma, unspecified
0.000 0.064 0.936
B37.8 Candidiasis of other sites
0.000 0.070 0.930
D50.9 Iron deficiency anaemia, unspecified
0.000 0.072 0.928
T50.9 Other and unspecified drugs, medicaments and biological substances
0.928 0.072 0.000
B34.9 Viral infection, unspecified
0.000 0.073 0.927
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.922 0.078 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.078 0.922
E04 Other non-toxic goitre
0.000 0.082 0.918
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.083 0.917
T36-T50 Poisoning by drugs, medicaments and biological substances
0.916 0.084 0.000
J22 Unspecified acute lower respiratory infection
0.000 0.084 0.916
M34.9 Systemic sclerosis, unspecified
0.000 0.084 0.916
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.086 0.914
J20 Acute bronchitis
0.000 0.102 0.898
K90.9 Intestinal malabsorption, unspecified
0.000 0.107 0.893
B37.0 Candidal stomatitis
0.000 0.115 0.885
D86.1 Sarcoidosis of lymph nodes
0.000 0.122 0.878
J33.9 Nasal polyp, unspecified
0.000 0.123 0.877
M91-M94 Chondropathies
0.000 0.123 0.877
B35 Dermatophytosis
0.000 0.124 0.876
E06 Thyroiditis
0.000 0.126 0.874
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.127 0.873
E53.9 Vitamin B deficiency, unspecified
0.000 0.130 0.870
Chapter VI Diseases of the nervous system
0.000 0.137 0.863
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.862 0.138 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.141 0.859
E27.2 Addisonian crisis
0.000 0.142 0.858
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.858 0.142 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.850 0.150 0.000
M35.1 Other overlap syndromes
0.000 0.151 0.849
J39 Other diseases of upper respiratory tract
0.000 0.151 0.849
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.845 0.155 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.160 0.840
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.168 0.832
M34.8 Other forms of systemic sclerosis
0.000 0.169 0.831
B37.9 Candidiasis, unspecified
0.000 0.169 0.831
M35.0 Sicca syndrome [Sjogren]
0.000 0.169 0.831
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.827 0.173 0.000
E05.8 Other thyrotoxicosis
0.000 0.176 0.824
E04.2 Non-toxic multinodular goitre
0.000 0.177 0.823
T47.1 Other antacids and anti-gastric-secretion drugs
0.818 0.182 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.816 0.184 0.000
M31.6 Other giant cell arteritis
0.000 0.187 0.813
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.187 0.813
M34.1 CR(E)ST syndrome
0.000 0.187 0.813
M12 Other specific arthropathies
0.000 0.191 0.809
B27 Infectious mononucleosis
0.000 0.193 0.807
J81 Pulmonary oedema
0.000 0.193 0.807
E04.0 Non-toxic diffuse goitre
0.000 0.193 0.807
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.196 0.804
A60 Anogenital herpesviral [herpes simplex] infections
0.000 0.197 0.803
D86.0 Sarcoidosis of lung
0.000 0.198 0.802
M31.3 Wegener's granulomatosis
0.000 0.201 0.799
M06.3 Rheumatoid nodule
0.000 0.202 0.798
M05.8 Other seropositive rheumatoid arthritis
0.000 0.205 0.795
M93 Other osteochondropathies
0.000 0.205 0.795
J20.9 Acute bronchitis, unspecified
0.000 0.208 0.792
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.208 0.792
E10.2 With renal complications
0.000 0.209 0.791
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.209 0.791
E06.3 Autoimmune thyroiditis
0.000 0.210 0.790
J44 Other chronic obstructive pulmonary disease
0.000 0.211 0.789
B35.1 Tinea unguium
0.000 0.214 0.786
T45.0 Antiallergic and antiemetic drugs
0.779 0.221 0.000
J21 Acute bronchiolitis
0.000 0.222 0.778
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.226 0.774
E07 Other disorders of thyroid
0.000 0.229 0.771
J46 Status asthmaticus
0.000 0.229 0.771
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.770 0.230 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.230 0.770
T45.1 Antineoplastic and immunosuppressive drugs
0.769 0.231 0.000
M32 Systemic lupus erythematosus
0.000 0.233 0.767
D51 Vitamin B12 deficiency anaemia
0.000 0.235 0.765
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.239 0.761
E10.3 With ophthalmic complications
0.000 0.239 0.760
E56 Other vitamin deficiencies
0.000 0.242 0.758
D53 Other nutritional anaemias
0.000 0.243 0.757
J20.8 Acute bronchitis due to other specified organisms
0.000 0.243 0.756
J84.8 Other specified interstitial pulmonary diseases
0.000 0.248 0.752
M10 Gout
0.000 0.248 0.751
J39.8 Other specified diseases of upper respiratory tract
0.000 0.249 0.751
E34 Other endocrine disorders
0.000 0.249 0.750
T46.4 Angiotensin-converting-enzyme inhibitors
0.750 0.250 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.257 0.743
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.258 0.742
B36 Other superficial mycoses
0.000 0.258 0.742
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.259 0.740
J95-J99 Other diseases of the respiratory system
0.000 0.260 0.740
E20 Hypoparathyroidism
0.000 0.262 0.738
E04.9 Non-toxic goitre, unspecified
0.000 0.262 0.738
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.263 0.737
M93.9 Osteochondropathy, unspecified
0.000 0.264 0.736
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.734 0.266 0.000
J32 Chronic sinusitis
0.000 0.267 0.733
B37.7 Candidal septicaemia
0.000 0.267 0.733
J40 Bronchitis, not specified as acute or chronic
0.000 0.267 0.733
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.268 0.732
J39.0 Retropharyngeal and parapharyngeal abscess
0.000 0.268 0.732
D86.8 Sarcoidosis of other and combined sites
0.000 0.272 0.728
M31.0 Hypersensitivity angiitis
0.000 0.273 0.727
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.725 0.275 0.000
E25 Adrenogenital disorders
0.000 0.275 0.725
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.276 0.724
E10.6 With other specified complications
0.000 0.277 0.723
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.279 0.721
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.279 0.720
E03.1 Congenital hypothyroidism without goitre
0.000 0.280 0.720
E10.0 With coma
0.000 0.280 0.720
A52 Late syphilis
0.000 0.281 0.719
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.281 0.719
B34.8 Other viral infections of unspecified site
0.000 0.282 0.718
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.718 0.282 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.718 0.282 0.000
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.283 0.717
E63 Other nutritional deficiencies
0.000 0.283 0.717
E50 Vitamin A deficiency
0.000 0.283 0.717
E60 Dietary zinc deficiency
0.000 0.283 0.717
E59 Dietary selenium deficiency
0.000 0.283 0.717
E52 Niacin deficiency [pellagra]
0.000 0.283 0.717
B37.2 Candidiasis of skin and nail
0.000 0.284 0.716
B25.8 Other cytomegaloviral diseases
0.000 0.284 0.716
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.284 0.716
A75-A79 Rickettsioses
0.000 0.284 0.716
A70-A74 Other diseases caused by chlamydiae
0.000 0.284 0.716
D81 Combined immunodeficiencies
0.000 0.284 0.716
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.284 0.716
M05.2 Rheumatoid vasculitis
0.000 0.284 0.716
M05.1 Rheumatoid lung disease
0.000 0.284 0.716
M05.0 Felty's syndrome
0.000 0.284 0.716
E27.5 Adrenomedullary hyperfunction
0.000 0.284 0.716
E27.0 Other adrenocortical overactivity
0.000 0.284 0.716
M08 Juvenile arthritis
0.000 0.284 0.716
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.284 0.715
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.284 0.715
M35.5 Multifocal fibrosclerosis
0.000 0.284 0.715
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.284 0.715
K90.3 Pancreatic steatorrhoea
0.000 0.285 0.715
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.285 0.715
K90.1 Tropical sprue
0.000 0.285 0.715
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.285 0.715
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.285 0.715
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.285 0.715
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.285 0.715
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.285 0.715
B30 Viral conjunctivitis
0.000 0.286 0.714
B26 Mumps
0.000 0.286 0.714
M35.8 Other specified systemic involvement of connective tissue
0.000 0.286 0.714
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.286 0.714
E32 Diseases of thymus
0.000 0.286 0.714
E31 Polyglandular dysfunction
0.000 0.286 0.714
E30 Disorders of puberty, not elsewhere classified
0.000 0.286 0.714
E53.1 Pyridoxine deficiency
0.000 0.286 0.714
E53.0 Riboflavin deficiency
0.000 0.286 0.714
A59 Trichomoniasis
0.000 0.286 0.714
A56 Other sexually transmitted chlamydial diseases
0.000 0.286 0.714
A54 Gonococcal infection
0.000 0.286 0.714
A53 Other and unspecified syphilis
0.000 0.286 0.714
A51 Early syphilis
0.000 0.286 0.714
A50 Congenital syphilis
0.000 0.286 0.714
A64 Unspecified sexually transmitted disease
0.000 0.286 0.714
A58 Granuloma inguinale
0.000 0.286 0.714
A57 Chancroid
0.000 0.286 0.714
A55 Chlamydial lymphogranuloma (venereum)
0.000 0.286 0.714
E55.0 Rickets, active
0.000 0.287 0.713
E10.1 With ketoacidosis
0.000 0.288 0.712
A63.8 Other specified predominantly sexually transmitted diseases
0.000 0.289 0.711
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.289 0.711
B35.6 Tinea cruris
0.000 0.291 0.709
E29 Testicular dysfunction
0.000 0.291 0.709
D55-D59 Haemolytic anaemias
0.000 0.293 0.707
M00-M03 Infectious arthropathies
0.000 0.294 0.706
B33 Other viral diseases, not elsewhere classified
0.000 0.294 0.706
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.295 0.705
B25.2 Cytomegaloviral pancreatitis
0.000 0.296 0.704
B25.1 Cytomegaloviral hepatitis
0.000 0.296 0.704
B25.0 Cytomegaloviral pneumonitis
0.000 0.296 0.704
T50.8 Diagnostic agents
0.703 0.297 0.000
B48 Other mycoses, not elsewhere classified
0.000 0.297 0.703
B47 Mycetoma
0.000 0.297 0.703
B46 Zygomycosis
0.000 0.297 0.703
B45 Cryptococcosis
0.000 0.297 0.703
B43 Chromomycosis and phaeomycotic abscess
0.000 0.297 0.703
B42 Sporotrichosis
0.000 0.297 0.703
B41 Paracoccidioidomycosis
0.000 0.297 0.703
B40 Blastomycosis
0.000 0.297 0.703
B39 Histoplasmosis
0.000 0.297 0.703
B38 Coccidioidomycosis
0.000 0.297 0.703
J43 Emphysema
0.000 0.298 0.702
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.701 0.299 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.301 0.699
K35-K38 Diseases of appendix
0.000 0.302 0.698
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.302 0.697
M34.0 Progressive systemic sclerosis
0.000 0.302 0.697
E51 Thiamine deficiency
0.000 0.303 0.697
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.303 0.697
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.303 0.697
M31.7 Microscopic polyangiitis
0.000 0.304 0.696
B50-B64 Protozoal diseases
0.000 0.304 0.696
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.306 0.694
D82 Immunodeficiency associated with other major defects
0.000 0.306 0.694
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.306 0.694
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.307 0.693
M22 Disorders of patella
0.000 0.307 0.693
E54 Ascorbic acid deficiency
0.000 0.307 0.693
B37.6 Candidal endocarditis
0.000 0.310 0.690
B37.5 Candidal meningitis
0.000 0.310 0.690
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.310 0.689
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.313 0.687
E26 Hyperaldosteronism
0.000 0.314 0.686
A65-A69 Other spirochaetal diseases
0.000 0.314 0.686
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.314 0.686
A15-A19 Tuberculosis
0.000 0.314 0.686
J32.0 Chronic maxillary sinusitis
0.000 0.315 0.685
E12 Malnutrition-related diabetes mellitus
0.000 0.316 0.684
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.317 0.683
E10.7 With multiple complications
0.000 0.317 0.683
D50.1 Sideropenic dysphagia
0.000 0.319 0.681
D52 Folate deficiency anaemia
0.000 0.321 0.679
B34.3 Parvovirus infection, unspecified
0.000 0.321 0.678
B34.2 Coronavirus infection, unspecified
0.000 0.321 0.678
B34.0 Adenovirus infection, unspecified
0.000 0.321 0.678
M31.8 Other specified necrotising vasculopathies
0.000 0.323 0.677
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.323 0.677
M31.2 Lethal midline granuloma
0.000 0.323 0.677
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.324 0.676
E06.9 Thyroiditis, unspecified
0.000 0.328 0.672
B27.9 Infectious mononucleosis, unspecified
0.000 0.328 0.672
J84.0 Alveolar and parietoalveolar conditions
0.000 0.329 0.671
B99-B99 Other infectious diseases
0.000 0.329 0.670
K70-K77 Diseases of liver
0.000 0.330 0.670
D84 Other immunodeficiencies
0.000 0.332 0.668
M30 Polyarteritis nodosa and related conditions
0.000 0.332 0.668
M91 Juvenile osteochondrosis of hip and pelvis
0.000 0.334 0.666
A60.0 Herpesviral infection of genitalia and urogenital tract
0.000 0.334 0.666
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.334 0.665
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.335 0.665
J80 Adult respiratory distress syndrome
0.000 0.335 0.665
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.664 0.335 0.000
M12.3 Palindromic rheumatism
0.000 0.336 0.664
M06.0 Seronegative rheumatoid arthritis
0.000 0.336 0.664
T42.3 Barbiturates
0.663 0.337 0.000
E61 Deficiency of other nutrient elements
0.000 0.338 0.662
K75 Other inflammatory liver diseases
0.000 0.338 0.662
T50.7 Analeptics and opioid receptor antagonists
0.661 0.339 0.000
T50.5 Appetite depressants
0.661 0.339 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.661 0.339 0.000
T50.1 Loop [high-ceiling] diuretics
0.661 0.339 0.000
T50.0 Mineralocorticoids and their antagonists
0.661 0.339 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.339 0.661
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.339 0.661
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.339 0.661
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.339 0.661
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.339 0.661
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.339 0.661
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.339 0.661
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.339 0.661
M22.2 Patellofemoral disorders
0.000 0.341 0.659
E04.8 Other specified non-toxic goitre
0.000 0.342 0.658
J45.8 Mixed asthma
0.000 0.342 0.658
T41 Poisoning by anaesthetics and therapeutic gases
0.657 0.343 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.343 0.657
J34 Other disorders of nose and nasal sinuses
0.000 0.344 0.656
T50.4 Drugs affecting uric acid metabolism
0.654 0.346 0.000
M10.0 Idiopathic gout
0.000 0.348 0.652
B37.4 Candidiasis of other urogenital sites
0.000 0.349 0.651
T47.4 Other laxatives
0.649 0.351 0.000
E06.1 Subacute thyroiditis
0.000 0.351 0.649
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.351 0.649
G37 Other demyelinating diseases of central nervous system
0.000 0.353 0.647
E34.0 Carcinoid syndrome
0.000 0.353 0.647
T42.0 Hydantoin derivatives
0.645 0.355 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.645 0.355 0.000
J20.7 Acute bronchitis due to echovirus
0.000 0.356 0.644
J20.6 Acute bronchitis due to rhinovirus
0.000 0.356 0.644
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.356 0.644
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.356 0.644
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.356 0.644
J20.2 Acute bronchitis due to streptococcus
0.000 0.356 0.644
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.356 0.644
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.356 0.644
K75.4 Autoimmune hepatitis
0.000 0.356 0.644
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.000 0.357 0.643
D83 Common variable immunodeficiency
0.000 0.360 0.640
E58 Dietary calcium deficiency
0.000 0.361 0.639
J21.9 Acute bronchiolitis, unspecified
0.000 0.367 0.633
J39.9 Disease of upper respiratory tract, unspecified
0.000 0.367 0.633
D50.8 Other iron deficiency anaemias
0.000 0.368 0.632
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.368 0.631
M35.2 Behcet's disease
0.000 0.369 0.631
M94 Other disorders of cartilage
0.000 0.371 0.629
K75.8 Other specified inflammatory liver diseases
0.000 0.371 0.629
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.628 0.372 0.000
B35.8 Other dermatophytoses
0.000 0.372 0.628
B35.5 Tinea imbricata
0.000 0.372 0.628
B35.4 Tinea corporis
0.000 0.372 0.628
B35.2 Tinea manuum
0.000 0.372 0.628
B35.0 Tinea barbae and tinea capitis
0.000 0.372 0.628
J37 Chronic laryngitis and laryngotracheitis
0.000 0.372 0.628
E06.4 Drug-induced thyroiditis
0.000 0.373 0.627
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.373 0.627
E06.0 Acute thyroiditis
0.000 0.373 0.627
M31.1 Thrombotic microangiopathy
0.000 0.376 0.624
T36 Poisoning by systemic antibiotics
0.624 0.376 0.000
E07.8 Other specified disorders of thyroid
0.000 0.376 0.624
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.623 0.376 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.618 0.382 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.618 0.382 0.000
T47.7 Emetics
0.618 0.382 0.000
T47.6 Antidiarrhoeal drugs
0.618 0.382 0.000
T47.5 Digestants
0.618 0.382 0.000
T47.3 Saline and osmotic laxatives
0.618 0.382 0.000
T47.2 Stimulant laxatives
0.618 0.382 0.000
T47.0 Histamine H(2)-receptor antagonists
0.618 0.382 0.000
D86.3 Sarcoidosis of skin
0.000 0.384 0.616
J41 Simple and mucopurulent chronic bronchitis
0.000 0.384 0.615
B44 Aspergillosis
0.000 0.385 0.615
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.615 0.385 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.615 0.385 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.615 0.385 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.615 0.385 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.615 0.385 0.000
T44.0 Anticholinesterase agents
0.615 0.385 0.000
G36 Other acute disseminated demyelination
0.000 0.385 0.615
K73 Chronic hepatitis, not elsewhere classified
0.000 0.386 0.614
K37 Unspecified appendicitis
0.000 0.387 0.613
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.613 0.387 0.000
J86 Pyothorax
0.000 0.387 0.613
T42.4 Benzodiazepines
0.613 0.387 0.000
J43.8 Other emphysema
0.000 0.389 0.611
J45.1 Nonallergic asthma
0.000 0.389 0.611
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.610 0.390 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.609 0.391 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.609 0.391 0.000
T46.7 Peripheral vasodilators
0.609 0.391 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.609 0.391 0.000
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified
0.000 0.392 0.608
M06.34 Rheumatoid nodule (Hand)
0.000 0.393 0.607
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.606 0.394 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.605 0.394 0.000
T45.8 Other primarily systemic and haematological agents
0.605 0.394 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.605 0.394 0.000
T45.6 Fibrinolysis-affecting drugs
0.605 0.394 0.000
T45.4 Iron and its compounds
0.605 0.394 0.000
T45.3 Enzymes, not elsewhere classified
0.605 0.394 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.000 0.397 0.603
J33.1 Polypoid sinus degeneration
0.000 0.398 0.602
M06.8 Other specified rheumatoid arthritis
0.000 0.399 0.600
A20-A28 Certain zoonotic bacterial diseases
0.000 0.399 0.600
D53.9 Nutritional anaemia, unspecified
0.000 0.399 0.601
B35.9 Dermatophytosis, unspecified
0.000 0.400 0.600
B35.3 Tinea pedis
0.000 0.400 0.600
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.600 0.400 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.402 0.598
J34.3 Hypertrophy of nasal turbinates
0.000 0.405 0.595
T42.5 Mixed antiepileptics, not elsewhere classified
0.593 0.407 0.000
T42.2 Succinimides and oxazolidinediones
0.593 0.407 0.000
M12.2 Villonodular synovitis (pigmented)
0.000 0.407 0.593
B34.1 Enterovirus infection, unspecified
0.000 0.408 0.592
J39.1 Other abscess of pharynx
0.000 0.408 0.592
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.591 0.409 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.409 0.591
D67 Hereditary factor IX deficiency
0.000 0.409 0.591
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.410 0.589
K51.5 Mucosal proctocolitis
0.000 0.411 0.589
T46.5 Other antihypertensive drugs, not elsewhere classified
0.587 0.413 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.587 0.413 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.414 0.586
E56.1 Deficiency of vitamin K
0.000 0.416 0.584
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.584 0.416 0.000
E27.9 Disorder of adrenal gland, unspecified
0.000 0.417 0.583
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.418 0.582
D68 Other coagulation defects
0.000 0.418 0.582
M10.07 Idiopathic gout (Ankle and foot)
0.000 0.418 0.582
M45-M49 Spondylopathies
0.000 0.420 0.580
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.420 0.580
M12.5 Traumatic arthropathy
0.000 0.420 0.580
M12.4 Intermittent hydrarthrosis
0.000 0.420 0.580
M12.1 Kaschin-Beck disease
0.000 0.420 0.580
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.420 0.580
B27.8 Other infectious mononucleosis
0.000 0.421 0.579
B27.1 Cytomegaloviral mononucleosis
0.000 0.421 0.579
B27.0 Gammaherpesviral mononucleosis
0.000 0.421 0.579
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.422 0.578
K38 Other diseases of appendix
0.000 0.424 0.576
A60.9 Anogenital herpesviral infection, unspecified
0.000 0.424 0.576
A60.1 Herpesviral infection of perianal skin and rectum
0.000 0.424 0.576
T38.8 Other and unspecified hormones and their synthetic substitutes
0.575 0.425 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.574 0.426 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.000 0.426 0.574
M31.9 Necrotising vasculopathy, unspecified
0.000 0.426 0.574
B65-B83 Helminthiases
0.000 0.427 0.573
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.428 0.572
M06.38 Rheumatoid nodule (Other)
0.000 0.428 0.572
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.428 0.572
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.428 0.572
M06.33 Rheumatoid nodule (Forearm)
0.000 0.428 0.572
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.428 0.572
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.428 0.572
B36.9 Superficial mycosis, unspecified
0.000 0.428 0.571
M02 Reactive arthropathies
0.000 0.429 0.570
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.430 0.570
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.430 0.570
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.430 0.570
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.430 0.570
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.430 0.570
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.430 0.570
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.430 0.570
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.430 0.570
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.430 0.570
M93.8 Other specified osteochondropathies
0.000 0.430 0.570
M93.2 Osteochondritis dissecans
0.000 0.430 0.570
M93.1 Kienbock's disease of adults
0.000 0.430 0.570
M93.0 Slipped upper femoral epiphysis (nontraumatic)
0.000 0.430 0.570
M92 Other juvenile osteochondrosis
0.000 0.432 0.568
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.432 0.568
E03.8 Other specified hypothyroidism
0.000 0.433 0.567
B07 Viral warts
0.000 0.433 0.567

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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