TreeWAS – Variant ID: rs310405

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J84.1 Other interstitial pulmonary diseases with fibrosis	0.289	0.711	0.000
J84 Other interstitial pulmonary diseases	0.269	0.731	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.259	0.741	0.000
J84.8 Other specified interstitial pulmonary diseases	0.215	0.785	0.000
J84.0 Alveolar and parietoalveolar conditions	0.206	0.794	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.109	0.891	0.000
J80 Adult respiratory distress syndrome	0.101	0.899	0.000
J81 Pulmonary oedema	0.051	0.949	0.000
I20.0 Unstable angina	0.000	0.950	0.050
J82 Pulmonary eosinophilia, not elsewhere classified	0.043	0.957	0.000
I20 Angina pectoris	0.000	0.960	0.040
I20.8 Other forms of angina pectoris	0.000	0.963	0.037
I20.1 Angina pectoris with documented spasm	0.000	0.966	0.033
I20.9 Angina pectoris, unspecified	0.000	0.976	0.024
T78.2 Anaphylactic shock, unspecified	0.000	0.989	0.011
T78 Adverse effects, not elsewhere classified	0.000	0.990	0.010
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.991	0.009
T78.0 Anaphylactic shock due to adverse food reaction	0.000	0.991	0.009
T78.8 Other adverse effects, not elsewhere classified	0.000	0.992	0.008
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.992	0.008
T78.9 Adverse effect, unspecified	0.000	0.992	0.008
E27.1 Primary adrenocortical insufficiency	0.000	0.993	0.007
E27 Other disorders of adrenal gland	0.000	0.993	0.007
F01.9 Vascular dementia, unspecified	0.000	0.993	0.007
T78.3 Angioneurotic oedema	0.000	0.994	0.006
E27.2 Addisonian crisis	0.000	0.994	0.006
J38.1 Polyp of vocal cord and larynx	0.006	0.994	0.000
Z29.1 Prophylactic immunotherapy	0.000	0.995	0.005
N73.9 Female pelvic inflammatory disease, unspecified	0.000	0.995	0.005
T66-T78 Other and unspecified effects of external causes	0.000	0.995	0.005
E27.5 Adrenomedullary hyperfunction	0.000	0.995	0.005
E27.0 Other adrenocortical overactivity	0.000	0.995	0.005
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.995	0.005
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.000	0.995	0.005
E27.9 Disorder of adrenal gland, unspecified	0.000	0.995	0.005
K11.2 Sialoadenitis	0.005	0.995	0.000
T66 Unspecified effects of radiation	0.000	0.995	0.005
I20-I25 Ischaemic heart diseases	0.000	0.995	0.005
G97.1 Other reaction to spinal and lumbar puncture	0.005	0.995	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.995	0.005
T78.4 Allergy, unspecified	0.000	0.995	0.005
T75 Effects of other external causes	0.000	0.995	0.005
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.995	0.005
T71 Asphyxiation	0.000	0.996	0.004
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.004	0.996	0.000
I22 Subsequent myocardial infarction	0.000	0.996	0.004
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.004	0.996	0.000
J38.0 Paralysis of vocal cords and larynx	0.004	0.996	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.996	0.004
T75.4 Effects of electric current	0.000	0.996	0.004
Z29.2 Other prophylactic chemotherapy	0.000	0.996	0.004
W13.9 Unspecified place	0.004	0.996	0.000
T74 Maltreatment syndromes	0.000	0.996	0.004
T73 Effects of other deprivation	0.000	0.996	0.004
T69 Other effects of reduced temperature	0.000	0.996	0.004
T67 Effects of heat and light	0.000	0.996	0.004
I24 Other acute ischaemic heart diseases	0.000	0.996	0.004
I22.8 Subsequent myocardial infarction of other sites	0.000	0.996	0.004
J38.6 Stenosis of larynx	0.004	0.996	0.000
J38.7 Other diseases of larynx	0.004	0.996	0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.000	0.996	0.004
T75.1 Drowning and nonfatal submersion	0.000	0.996	0.003
M25.46 Effusion of joint (Lower leg)	0.004	0.996	0.000
T75.8 Other specified effects of external causes	0.000	0.996	0.003
T75.3 Motion sickness	0.000	0.996	0.003
T75.2 Effects of vibration	0.000	0.996	0.003
T75.0 Effects of lightning	0.000	0.996	0.003
Z29 Need for other prophylactic measures	0.000	0.996	0.004
J38.5 Laryngeal spasm	0.003	0.997	0.000
T70 Effects of air pressure and water pressure	0.000	0.997	0.003
K25.4 Chronic or unspecified with haemorrhage	0.003	0.997	0.000
J38.4 Oedema of larynx	0.003	0.997	0.000
I24.1 Dressler's syndrome	0.000	0.997	0.003
S90.9 Superficial injury of ankle and foot, unspecified	0.000	0.997	0.003
J38.2 Nodules of vocal cords	0.003	0.997	0.000
I23 Certain current complications following acute myocardial infarction	0.000	0.997	0.003
T67.9 Effects of heat and light, unspecified	0.000	0.997	0.003
T67.8 Other effects of heat and light	0.000	0.997	0.003
T67.7 Heat oedema	0.000	0.997	0.003
T67.6 Heat fatigue, transient	0.000	0.997	0.003
T67.5 Heat exhaustion, unspecified	0.000	0.997	0.003
T67.4 Heat exhaustion due to salt depletion	0.000	0.997	0.003
T67.3 Heat exhaustion, anhydrotic	0.000	0.997	0.003
T67.2 Heat cramp	0.000	0.997	0.003
T67.1 Heat syncope	0.000	0.997	0.003
T67.0 Heatstroke and sunstroke	0.000	0.997	0.003
T69.9 Effect of reduced temperature, unspecified	0.000	0.997	0.003
T69.8 Other specified effects of reduced temperature	0.000	0.997	0.003
T69.1 Chilblains	0.000	0.997	0.003
T69.0 Immersion hand and foot	0.000	0.997	0.003
T73.9 Effect of deprivation, unspecified	0.000	0.997	0.003
T73.8 Other effects of deprivation	0.000	0.997	0.003
T73.3 Exhaustion due to excessive exertion	0.000	0.997	0.003
T73.2 Exhaustion due to exposure	0.000	0.997	0.003
T73.1 Effects of thirst	0.000	0.997	0.003
T73.0 Effects of hunger	0.000	0.997	0.003
T74.9 Maltreatment syndrome, unspecified	0.000	0.997	0.003
T74.8 Other maltreatment syndromes	0.000	0.997	0.003
T74.3 Psychological abuse	0.000	0.997	0.003
T74.2 Sexual abuse	0.000	0.997	0.003
T74.1 Physical abuse	0.000	0.997	0.003
T74.0 Neglect or abandonment	0.000	0.997	0.003
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.003	0.997	0.000
G57.6 Lesion of plantar nerve	0.000	0.997	0.003
J69.0 Pneumonitis due to food and vomit	0.000	0.997	0.003
J98.0 Diseases of bronchus, not elsewhere classified	0.003	0.997	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.003	0.997	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.003	0.997	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.997	0.003
Z29.9 Prophylactic measure, unspecified	0.000	0.997	0.003
F01 Vascular dementia	0.000	0.997	0.003
K11 Diseases of salivary glands	0.003	0.997	0.000
K11.7 Disturbances of salivary secretion	0.003	0.997	0.000
T70.9 Effect of air pressure and water pressure, unspecified	0.000	0.997	0.002
T70.8 Other effects of air pressure and water pressure	0.000	0.997	0.002
T70.4 Effects of high-pressure fluids	0.000	0.997	0.002
T70.2 Other and unspecified effects of high altitude	0.000	0.997	0.002
T70.1 Sinus barotrauma	0.000	0.997	0.002
T70.0 Otitic barotrauma	0.000	0.997	0.002
D33.3 Cranial nerves	0.000	0.997	0.003
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.003	0.997	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.003	0.997	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.997	0.002
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.997	0.002
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.997	0.002
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.997	0.002
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.997	0.002
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.997	0.002
Z85.4 Personal history of malignant neoplasm of genital organs	0.000	0.997	0.003
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.003	0.997	0.000
T68 Hypothermia	0.000	0.998	0.002
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.002	0.998	0.000
I23.8 Other current complications following acute myocardial infarction	0.000	0.998	0.002
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.002	0.998	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.002	0.998	0.000
K11.6 Mucocele of salivary gland	0.002	0.998	0.000
F01.8 Other vascular dementia	0.000	0.998	0.002
F01.3 Mixed cortical and subcortical vascular dementia	0.000	0.998	0.002
F01.2 Subcortical vascular dementia	0.000	0.998	0.002
F01.0 Vascular dementia of acute onset	0.000	0.998	0.002
K11.5 Sialolithiasis	0.002	0.998	0.000
K11.4 Fistula of salivary gland	0.002	0.998	0.000
K11.0 Atrophy of salivary gland	0.002	0.998	0.000
K11.1 Hypertrophy of salivary gland	0.002	0.998	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.002	0.998	0.000
D09.0 Bladder	0.002	0.998	0.000
M79.63 Pain in limb (Forearm)	0.000	0.998	0.002
Z29.0 Isolation	0.000	0.998	0.002
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.998	0.002
M77.47 Metatarsalgia-Ankle/Foot	0.000	0.998	0.002
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.002	0.998	0.000
T70.3 Caisson disease [decompression sickness]	0.000	0.998	0.002
Z29.8 Other specified prophylactic measures	0.000	0.998	0.002
F01.1 Multi-infarct dementia	0.000	0.998	0.002
K11.8 Other diseases of salivary glands	0.002	0.998	0.000
K25.7 Chronic without haemorrhage or perforation	0.000	0.998	0.002
S52.60 Fracture of lower end of both ulna and radius (closed)	0.002	0.998	0.000
K11.3 Abscess of salivary gland	0.002	0.998	0.000
Z00.6 Examination for normal comparison and control in clinical research programme	0.000	0.998	0.002
W13 Fall from, out of or through building or structure	0.002	0.998	0.000
H55 Nystagmus and other irregular eye movements	0.002	0.998	0.000
O14.1 Severe preeclampsia	0.000	0.998	0.002
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.002	0.998	0.000
H57.1 Ocular pain	0.002	0.998	0.000
I71.0 Dissection of aorta [any part]	0.002	0.998	0.000
N60.0 Solitary cyst of breast	0.000	0.998	0.002
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.002	0.998	0.000
K11.9 Disease of salivary gland, unspecified	0.002	0.998	0.000
S90 Superficial injury of ankle and foot	0.000	0.998	0.002
M24.07 Loose body in joint (Ankle and foot)	0.000	0.998	0.002
O43.1 Malformation of placenta	0.000	0.998	0.002
S90.0 Contusion of ankle	0.000	0.998	0.002
J69 Pneumonitis due to solids and liquids	0.000	0.998	0.002
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.998	0.002
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.002	0.998	0.000
G97.8 Other postprocedural disorders of nervous system	0.002	0.998	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.002	0.998	0.000
J69.8 Pneumonitis due to other solids and liquids	0.000	0.998	0.002
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.002	0.998	0.000
W13.6 Industrial and construction area	0.002	0.998	0.000
O14.0 Moderate preeclampsia	0.000	0.998	0.002
Y84.2 Radiological procedure and radiotherapy	0.000	0.998	0.002
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.998	0.002
I71.3 Abdominal aortic aneurysm, ruptured	0.002	0.998	0.000
W13.8 Other specified place	0.002	0.998	0.000
W13.0 Home	0.002	0.998	0.000
W13.7 Farm	0.002	0.998	0.000
W13.5 Trade and service area	0.002	0.998	0.000
W13.3 Sports and athletics area	0.002	0.998	0.000
W13.2 School, other institution and public administrative area	0.002	0.998	0.000
W13.1 Residential institution	0.002	0.998	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.002	0.998	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.002	0.998	0.000
Z45.1 Adjustment and management of infusion pump	0.002	0.998	0.000
R76.8 Other specified abnormal immunological findings in serum	0.002	0.998	0.000
W13.4 Street and highway	0.002	0.998	0.000
D05.0 Lobular carcinoma in situ	0.002	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.000	0.998	0.002
S90.2 Contusion of toe(s) with damage to nail	0.000	0.998	0.002
S97.8 Crushing injury of other parts of ankle and foot	0.000	0.998	0.002
Z90.1 Acquired absence of breast(s)	0.000	0.998	0.002
E28.2 Polycystic ovarian syndrome	0.000	0.998	0.002
D33 Benign neoplasm of brain and other parts of central nervous system	0.000	0.998	0.002
J99.8 Respiratory disorders in other diseases classified elsewhere	0.002	0.998	0.000
J69.1 Pneumonitis due to oils and essences	0.000	0.998	0.001
S82.20 Fracture of shaft of tibia (closed)	0.000	0.998	0.002
J15.2 Pneumonia due to staphylococcus	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.000	0.998	0.001
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
M46.46 Discitis, unspecified (Lumbar region)	0.002	0.998	0.000
D33.2 Brain, unspecified	0.000	0.998	0.002
I70.2 Atherosclerosis of arteries of the extremities	0.002	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.000	0.998	0.002
I71 Aortic aneurysm and dissection	0.002	0.998	0.000
R81 Glycosuria	0.002	0.998	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.998	0.002
I71.1 Thoracic aortic aneurysm, ruptured	0.002	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.000	0.998	0.001
D33.4 Spinal cord	0.000	0.998	0.002
Z48.0 Attention to surgical dressings and sutures	0.002	0.998	0.000
J20.9 Acute bronchitis, unspecified	0.002	0.998	0.000
W13.08 Fall from, out of or through building or structure; Home; While engaged in other specified activities	0.001	0.998	0.000
W13.89 Fall from, out of or through building or structure; Other specified places; During unspecified activity	0.001	0.998	0.000
D33.0 Brain, supratentorial	0.000	0.998	0.001
M79.54 Residual foreign body in soft tissue (Hand)	0.000	0.998	0.002
C48.2 Peritoneum, unspecified	0.000	0.998	0.002
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.998	0.002
M24.02 Loose body in joint (Upper arm)	0.000	0.998	0.001
S92.50 Fracture of other toe (closed)	0.000	0.998	0.001
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.998	0.001
C84.5 Other and unspecified T-cell lymphomas	0.001	0.998	0.000
D33.9 Central nervous system, unspecified	0.000	0.998	0.001
D33.7 Other specified parts of central nervous system	0.000	0.998	0.001
D33.1 Brain, infratentorial	0.000	0.998	0.001
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.998	0.001
G97.0 Cerebrospinal fluid leak from spinal puncture	0.001	0.998	0.000
M31.6 Other giant cell arteritis	0.002	0.998	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.000	0.998	0.001
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.001	0.999	0.000
D66 Hereditary factor VIII deficiency	0.001	0.999	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.001	0.999	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.999	0.001
F31.7 Bipolar affective disorder, currently in remission	0.000	0.999	0.001
G70.9 Myoneural disorder, unspecified	0.001	0.999	0.000
H69.9 Eustachian tube disorder, unspecified	0.001	0.999	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.001	0.999	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.001	0.999	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.000	0.999	0.001
I71.8 Aortic aneurysm of unspecified site, ruptured	0.001	0.999	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.001	0.999	0.000
J20.8 Acute bronchitis due to other specified organisms	0.001	0.999	0.000
M24.0 Loose body in joint	0.000	0.999	0.001
F31 Bipolar affective disorder	0.000	0.999	0.001
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.001	0.999	0.000
M54.29 Cervicalgia-Site unspe	0.000	0.999	0.001
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.999	0.001
S92.40 Fracture of great toe (closed)	0.000	0.999	0.001
E28 Ovarian dysfunction	0.000	0.999	0.001
M05 Seropositive rheumatoid arthritis	0.001	0.999	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.001	0.999	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.999	0.001
M86.66 Other chronic osteomyelitis (Lower leg)	0.001	0.999	0.000
G61.0 Guillain-Barre syndrome	0.001	0.999	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.001	0.999	0.000
M24.06 Loose body in joint-Lower leg	0.000	0.999	0.001
M24.05 Loose body in joint (Pelvic region and thigh)	0.000	0.999	0.001
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.001	0.999	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.999	0.001
I97.0 Postcardiotomy syndrome	0.001	0.999	0.000
M05.1 Rheumatoid lung disease	0.001	0.999	0.000
S52.6 Fracture of lower end of both ulna and radius	0.001	0.999	0.000
M24.03 Loose body in joint (Forearm)	0.000	0.999	0.001
I97.9 Postprocedural disorder of circulatory system, unspecified	0.001	0.999	0.000
M31.9 Necrotising vasculopathy, unspecified	0.001	0.999	0.000
M77.4 Metatarsalgia	0.000	0.999	0.001
O14.2 HELLP syndrome	0.000	0.999	0.001
Z76.8 Persons encountering health services in other specified circumstances	0.001	0.999	0.000
M24.04 Loose body in joint (Hand)	0.000	0.999	0.001
J38.3 Other diseases of vocal cords	0.001	0.999	0.000
S92.5 Fracture of other toe	0.000	0.999	0.001
Z41 Procedures for purposes other than remedying health state	0.000	0.999	0.001
M24.09 Loose body in joint (Site unspecified)	0.000	0.999	0.001
M24.08 Loose body in joint (Other)	0.000	0.999	0.001
M24.00 Loose body in joint (Multiple sites)	0.000	0.999	0.001
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.001	0.999	0.000
S82.31 Fracture of lower end of tibia (open)	0.001	0.999	0.000
C11.9 Nasopharynx, unspecified	0.000	0.999	0.001
E28.3 Primary ovarian failure	0.000	0.999	0.001
E31.0 Autoimmune polyglandular failure	0.000	0.999	0.001
J04.1 Acute tracheitis	0.000	0.999	0.001
J11.1 Influenza with other respiratory manifestations, virus not identified	0.001	0.999	0.000
J99.0 Rheumatoid lung disease	0.001	0.999	0.000
W08.0 Home	0.001	0.999	0.000
J20 Acute bronchitis	0.001	0.999	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.001	0.999	0.000
H17.9 Corneal scar and opacity, unspecified	0.001	0.999	0.000
M05.2 Rheumatoid vasculitis	0.001	0.999	0.000
M20.4 Other hammer toe(s) (acquired)	0.000	0.999	0.001
C18.1 Appendix	0.000	0.999	0.001
E28.9 Ovarian dysfunction, unspecified	0.000	0.999	0.001
E28.8 Other ovarian dysfunction	0.000	0.999	0.001
E28.1 Androgen excess	0.000	0.999	0.001
E28.0 Oestrogen excess	0.000	0.999	0.001
E34.9 Endocrine disorder, unspecified	0.000	0.999	0.001
H20.9 Iridocyclitis, unspecified	0.001	0.999	0.000
J92.0 Pleural plaque with presence of asbestos	0.000	0.999	0.001
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.001	0.999	0.000
M05.0 Felty's syndrome	0.001	0.999	0.000
M31.7 Microscopic polyangiitis	0.001	0.999	0.000
X58.9 Unspecified place	0.000	0.999	0.001
M31 Other necrotising vasculopathies	0.001	0.999	0.000
M05.18 Rheumatoid lung disease (Other)	0.001	0.999	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.001	0.999	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.001	0.999	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.001	0.999	0.000
M05.14 Rheumatoid lung disease (Hand)	0.001	0.999	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.001	0.999	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.001	0.999	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.001	0.999	0.000
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)	0.001	0.999	0.000
I25.5 Ischaemic cardiomyopathy	0.000	0.999	0.001
M50.3 Other cervical disk degeneration	0.001	0.999	0.000
M86.6 Other chronic osteomyelitis	0.001	0.999	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.001	0.999	0.000
S97 Crushing injury of ankle and foot	0.000	0.999	0.001
M05.29 Rheumatoid vasculitis (Site unspecified)	0.001	0.999	0.000
S52.70 Multiple fractures of forearm (closed)	0.001	0.999	0.000
S92.51 Fracture of other toe (open)	0.000	0.999	0.001
M31.1 Thrombotic microangiopathy	0.001	0.999	0.000
M31.0 Hypersensitivity angiitis	0.001	0.999	0.000
S92.4 Fracture of great toe	0.000	0.999	0.001
Z41.2 Routine and ritual circumcision	0.000	0.999	0.001
I70.80 Atherosclerosis of other arteries (without gangrene)	0.001	0.999	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.001	0.999	0.000
M24.01 Loose body in joint (Shoulder region)	0.000	0.999	0.001
M77.49 Metatarsalgia-Site unspec	0.000	0.999	0.001
M77.48 Metatarsalgia-Other	0.000	0.999	0.001
M77.46 Metatarsalgia-Lower Leg	0.000	0.999	0.001
M77.45 Metatarsalgia-Pelvic/Thigh	0.000	0.999	0.001
M77.44 Metatarsalgia-Hand	0.000	0.999	0.001
M77.43 Metatarsalgia-Forearm	0.000	0.999	0.001
M77.42 Metatarsalgia-Upper arm	0.000	0.999	0.001
M77.41 Metatarsalgia-Shldr region	0.000	0.999	0.001
M77.40 Metatarsalgia-Mult sites	0.000	0.999	0.001
I97.1 Other functional disturbances following cardiac surgery	0.001	0.999	0.000
J15.5 Pneumonia due to Escherichia coli	0.001	0.999	0.000
M31.8 Other specified necrotising vasculopathies	0.001	0.999	0.000
M31.3 Wegener's granulomatosis	0.001	0.999	0.000
O03.4 Incomplete, without complication	0.000	0.999	0.001
Q07.0 Arnold-Chiari syndrome	0.000	0.999	0.001
Z41.3 Ear piercing	0.000	0.999	0.001
Z41.0 Hair transplant	0.000	0.999	0.001
H57 Other disorders of eye and adnexa	0.001	0.999	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.999	0.001
J20.7 Acute bronchitis due to echovirus	0.001	0.999	0.000
J20.6 Acute bronchitis due to rhinovirus	0.001	0.999	0.000
J20.5 Acute bronchitis due to respiratory syncytial virus	0.001	0.999	0.000
J20.4 Acute bronchitis due to parainfluenza virus	0.001	0.999	0.000
J20.3 Acute bronchitis due to coxsackie virus	0.001	0.999	0.000
J20.2 Acute bronchitis due to streptococcus	0.001	0.999	0.000
J20.1 Acute bronchitis due to Haemophilus influenzae	0.001	0.999	0.000
J20.0 Acute bronchitis due to Mycoplasma pneumoniae	0.001	0.999	0.000
M05.28 Rheumatoid vasculitis (Other)	0.001	0.999	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.001	0.999	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.001	0.999	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.001	0.999	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.001	0.999	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.001	0.999	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.001	0.999	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.001	0.999	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M48.09 Spinal stenosis (Site unspecified)	0.001	0.999	0.000
M86.69 Other chronic osteomyelitis (Site unspecified)	0.001	0.999	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.999	0.001
C49.3 Connective and soft tissue of thorax	0.000	0.999	0.001
F31.8 Other bipolar affective disorders	0.000	0.999	0.001
H59.8 Other postprocedural disorders of eye and adnexa	0.001	0.999	0.000
M05.8 Other seropositive rheumatoid arthritis	0.001	0.999	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.001	0.999	0.000
M05.09 Felty's syndrome (Site unspecified)	0.001	0.999	0.000
M05.08 Felty's syndrome (Other)	0.001	0.999	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.001	0.999	0.000
M05.06 Felty's syndrome (Lower leg)	0.001	0.999	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.001	0.999	0.000
M05.04 Felty's syndrome (Hand)	0.001	0.999	0.000
M05.03 Felty's syndrome (Forearm)	0.001	0.999	0.000
M05.02 Felty's syndrome (Upper arm)	0.001	0.999	0.000
M05.01 Felty's syndrome (Shoulder region)	0.001	0.999	0.000
M05.00 Felty's syndrome (Multiple sites)	0.001	0.999	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.001	0.999	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.001	0.999	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.001	0.999	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.001	0.999	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.001	0.999	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.001	0.999	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.001	0.999	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.001	0.999	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.001	0.999	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.001	0.999	0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.001	0.999	0.000
M86.64 Other chronic osteomyelitis (Hand)	0.001	0.999	0.000
M86.63 Other chronic osteomyelitis (Forearm)	0.001	0.999	0.000
M86.62 Other chronic osteomyelitis (Upper arm)	0.001	0.999	0.000
M86.61 Other chronic osteomyelitis (Shoulder region)	0.001	0.999	0.000
M86.60 Other chronic osteomyelitis (Multiple sites)	0.001	0.999	0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.001	0.999	0.000
M86.96 Osteomyelitis, unspecified (Lower leg)	0.001	0.999	0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.001	0.999	0.000
S06.00 Concussion (without open intracranial wound)	0.001	0.999	0.000
C32.0 Glottis	0.001	0.999	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.999	0.001
M31.2 Lethal midline granuloma	0.001	0.999	0.000
O14.9 Preeclampsia, unspecified	0.000	0.999	0.001
M05.20 Rheumatoid vasculitis (Multiple sites)	0.001	0.999	0.000
S92.41 Fracture of great toe (open)	0.000	0.999	0.001
G53.0 Postzoster neuralgia	0.000	0.999	0.001
J15.1 Pneumonia due to Pseudomonas	0.001	0.999	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.001	0.999	0.000
S97.0 Crushing injury of ankle	0.000	0.999	0.001
E31 Polyglandular dysfunction	0.000	0.999	0.001
I25 Chronic ischaemic heart disease	0.000	0.999	0.001
M87.05 Idiopathic aseptic necrosis of bone (Pelvic region and thigh)	0.001	0.999	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.001	0.999	0.000
M86.9 Osteomyelitis, unspecified	0.001	0.999	0.000
O72.1 Other immediate postpartum haemorrhage	0.000	0.999	0.001
S92.2 Fracture of other tarsal bone(s)	0.000	0.999	0.001
Z41.9 Procedures for purposes other than remedying health state, unspecified	0.000	0.999	0.001
H55-H59 Other disorders of eye and adnexa	0.001	0.999	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.001	0.999	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.001	0.999	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.001	0.999	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.001	0.999	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.001	0.999	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.001	0.999	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.001	0.999	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.001	0.999	0.000
M86.68 Other chronic osteomyelitis (Other)	0.001	0.999	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
I25.1 Atherosclerotic heart disease	0.000	0.999	0.001
I70.8 Atherosclerosis of other arteries	0.001	0.999	0.000
R59.1 Generalised enlarged lymph nodes	0.001	0.999	0.000
S99.9 Unspecified injury of ankle and foot	0.000	0.999	0.001
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.999	0.001
J13 Pneumonia due to Streptococcus pneumoniae	0.001	0.999	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.001	0.999	0.000
C67.6 Ureteric orifice	0.000	0.999	0.001
C84.8 Cutaneous T-cell lymphoma, unspecified	0.001	0.999	0.000
D07.5 Prostate	0.000	0.999	0.001
E11.5 With peripheral circulatory complications	0.000	0.999	0.001
K61.3 Ischiorectal abscess	0.000	0.999	0.001
M31.4 Aortic arch syndrome [Takayasu]	0.001	0.999	0.000
M88.9 Paget's disease of bone, unspecified	0.001	0.999	0.000
E34 Other endocrine disorders	0.000	0.999	0.001
I21 Acute myocardial infarction	0.000	0.999	0.001
I70.00 Atherosclerosis of aorta (without gangrene)	0.001	0.999	0.000
M65.84 Other synovitis and tenosynovitis (Hand)	0.001	0.999	0.000
M86.93 Osteomyelitis, unspecified (Forearm)	0.001	0.999	0.000
M86.92 Osteomyelitis, unspecified (Upper arm)	0.001	0.999	0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.001	0.999	0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.001	0.999	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.001	0.999	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.001	0.999	0.000
S52.40 Fracture of shafts of both ulna and radius (closed)	0.001	0.999	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.001	0.999	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.000	0.999	0.001
C50.3 Lower-inner quadrant of breast	0.000	0.999	0.001
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.999	0.001
E31.9 Polyglandular dysfunction, unspecified	0.000	0.999	0.001
E31.8 Other polyglandular dysfunction	0.000	0.999	0.001
E31.1 Polyglandular hyperfunction	0.000	0.999	0.001
G57.5 Tarsal tunnel syndrome	0.000	0.999	0.001
H58.8 Visual disturbances in diseases classified elsewhere	0.000	0.999	0.001
I24.8 Other forms of acute ischaemic heart disease	0.000	0.999	0.001
Q82.2 Mastocytosis	0.001	0.999	0.000
T46.1 Calcium-channel blockers	0.000	0.999	0.001
W11.4 Street and highway	0.001	0.999	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.001	0.999	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.001	0.999	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.001	0.999	0.000
M88.98 Paget's disease of bone, unspecified (Other)	0.001	0.999	0.000
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.001	0.999	0.000
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.001	0.999	0.000
M88.94 Paget's disease of bone, unspecified (Hand)	0.001	0.999	0.000
M88.93 Paget's disease of bone, unspecified (Forearm)	0.001	0.999	0.000
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.001	0.999	0.000
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.001	0.999	0.000
E34.3 Short stature, not elsewhere classified	0.000	0.999	0.001
H59.0 Vitreous syndrome following cataract surgery	0.001	0.999	0.000
I25.6 Silent myocardial ischaemia	0.000	0.999	0.001
I70.0 Atherosclerosis of aorta	0.001	0.999	0.000
G57 Mononeuropathies of lower limb	0.000	0.999	0.001
S92 Fracture of foot, except ankle	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations