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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3104402
log Bayes Factor = 71.832
Chromosome 6   position 32,681,676  (GRCh37) Explore rs3104402 on Ensembl!
Variant rs3104402 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.001 0.999
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.004 0.996
E16 Other disorders of pancreatic internal secretion
0.000 0.007 0.993
E16.2 Hypoglycaemia, unspecified
0.000 0.009 0.991
E14 Unspecified diabetes mellitus
0.000 0.016 0.984
J45.9 Asthma, unspecified
0.000 0.023 0.977
E78.0 Pure hypercholesterolaemia
0.000 0.024 0.976
E70-E90 Metabolic disorders
0.001 0.024 0.974
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.025 0.975
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.035 0.965
E14.3 With ophthalmic complications
0.000 0.041 0.959
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.044 0.956
M06 Other rheumatoid arthritis
0.000 0.054 0.946
K51.9 Ulcerative colitis, unspecified
0.944 0.056 0.000
E83 Disorders of mineral metabolism
0.922 0.062 0.016
K51 Ulcerative colitis
0.933 0.067 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.072 0.928
E11.2 With renal complications
0.000 0.072 0.928
E13 Other specified diabetes mellitus
0.000 0.077 0.923
K51.3 Ulcerative (chronic) rectosigmoiditis
0.902 0.098 0.000
K51.2 Ulcerative (chronic) proctitis
0.884 0.116 0.000
E11.5 With peripheral circulatory complications
0.000 0.131 0.869
E13.9 Without complications
0.000 0.132 0.868
E83.5 Disorders of calcium metabolism
0.864 0.134 0.001
G35-G37 Demyelinating diseases of the central nervous system
0.860 0.140 0.000
E14.9 Without complications
0.000 0.141 0.859
E06 Thyroiditis
0.000 0.146 0.854
M05-M14 Inflammatory polyarthropathies
0.000 0.154 0.846
E78.5 Hyperlipidaemia, unspecified
0.000 0.163 0.837
M05 Seropositive rheumatoid arthritis
0.000 0.168 0.832
G37 Other demyelinating diseases of central nervous system
0.830 0.170 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.178 0.822
E11.1 With ketoacidosis
0.000 0.180 0.820
K51.5 Mucosal proctocolitis
0.819 0.181 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.184 0.816
K51.8 Other ulcerative colitis
0.813 0.187 0.000
E11.6 With other specified complications
0.000 0.192 0.808
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.198 0.802
E83.3 Disorders of phosphorus metabolism
0.795 0.199 0.007
M06.0 Seronegative rheumatoid arthritis
0.000 0.201 0.799
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.204 0.796
E78.2 Mixed hyperlipidaemia
0.000 0.213 0.787
E06.3 Autoimmune thyroiditis
0.000 0.213 0.787
G37.9 Demyelinating disease of central nervous system, unspecified
0.785 0.215 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.232 0.768
M06.4 Inflammatory polyarthropathy
0.000 0.261 0.739
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.265 0.735
M07 Psoriatic and enteropathic arthropathies
0.000 0.266 0.734
E11.8 With unspecified complications
0.000 0.269 0.731
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.269 0.730
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.277 0.723
E78.1 Pure hyperglyceridaemia
0.000 0.277 0.723
E40-E46 Malnutrition
0.000 0.278 0.721
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.5 With peripheral circulatory complications
0.000 0.283 0.717
E10.4 With neurological complications
0.000 0.283 0.717
E10.2 With renal complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.8 Other specified hypothyroidism
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.286 0.714
K90.0 Coeliac disease
0.000 0.287 0.713
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.288 0.712
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.288 0.712
E16.4 Abnormal secretion of gastrin
0.000 0.288 0.712
E16.3 Increased secretion of glucagon
0.000 0.288 0.712
E16.1 Other hypoglycaemia
0.000 0.288 0.712
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.288 0.712
E14.8 With unspecified complications
0.000 0.294 0.705
E14.7 With multiple complications
0.000 0.294 0.705
E14.6 With other specified complications
0.000 0.294 0.705
E14.5 With peripheral circulatory complications
0.000 0.294 0.705
E14.4 With neurological complications
0.000 0.294 0.705
E14.2 Withrenal complications
0.000 0.294 0.705
E14.1 With ketoacidosis
0.000 0.294 0.705
E14.0 With coma
0.000 0.294 0.705
M06.3 Rheumatoid nodule
0.000 0.299 0.701
E84 Cystic fibrosis
0.001 0.300 0.698
E77 Disorders of glycoprotein metabolism
0.001 0.300 0.698
E76 Disorders of glycosaminoglycan metabolism
0.001 0.300 0.698
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.300 0.698
E74 Other disorders of carbohydrate metabolism
0.001 0.300 0.698
E72 Other disorders of amino-acid metabolism
0.001 0.300 0.698
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.300 0.698
E70 Disorders of aromatic amino-acid metabolism
0.001 0.300 0.698
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.300 0.698
E78.6 Lipoprotein deficiency
0.000 0.301 0.699
E78.3 Hyperchylomicronaemia
0.000 0.301 0.699
G37.8 Other specified demyelinating diseases of central nervous system
0.689 0.311 0.000
E07 Other disorders of thyroid
0.000 0.314 0.686
E11.0 With coma
0.000 0.320 0.680
M06.8 Other specified rheumatoid arthritis
0.000 0.322 0.678
M06.2 Rheumatoid bursitis
0.000 0.322 0.678
M06.1 Adult-onset Still's disease
0.000 0.322 0.678
E83.9 Disorder of mineral metabolism, unspecified
0.661 0.328 0.011
E83.8 Other disorders of mineral metabolism
0.661 0.328 0.011
E83.2 Disorders of zinc metabolism
0.661 0.328 0.011
E83.0 Disorders of copper metabolism
0.661 0.328 0.011
K51.1 Ulcerative (chronic) ileocolitis
0.669 0.331 0.000
E13.8 With unspecified complications
0.000 0.338 0.662
E13.7 With multiple complications
0.000 0.338 0.662
E13.6 With other specified complications
0.000 0.338 0.662
E13.5 With peripheral circulatory complications
0.000 0.338 0.662
E13.4 With neurological complications
0.000 0.338 0.662
E13.3 With ophthalmic complications
0.000 0.338 0.662
E13.2 With renal complications
0.000 0.338 0.662
E13.1 With ketoacidosis
0.000 0.338 0.662
E13.0 With coma
0.000 0.338 0.662
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.338 0.661
M07.3 Other psoriatic arthropathies
0.000 0.346 0.654
E88 Other metabolic disorders
0.001 0.347 0.652
E78.4 Other hyperlipidaemia
0.000 0.351 0.649
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.640 0.360 0.000
E73 Lactose intolerance
0.001 0.372 0.627
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.374 0.626
E11.4 With neurological complications
0.000 0.376 0.624
E79 Disorders of purine and pyrimidine metabolism
0.001 0.378 0.621
G36 Other acute disseminated demyelination
0.617 0.383 0.000
E50-E64 Other nutritional deficiencies
0.000 0.383 0.617
M11 Other crystal arthropathies
0.000 0.385 0.615
E06.5 Other chronic thyroiditis
0.000 0.387 0.612
E06.4 Drug-induced thyroiditis
0.000 0.387 0.612
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.387 0.612
E06.1 Subacute thyroiditis
0.000 0.387 0.612
E06.0 Acute thyroiditis
0.000 0.387 0.612
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.390 0.610
M12 Other specific arthropathies
0.000 0.393 0.607
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.393 0.607
M08 Juvenile arthritis
0.000 0.393 0.607
M14 Arthropathies in other diseases classified elsewhere
0.000 0.396 0.603
M05.8 Other seropositive rheumatoid arthritis
0.000 0.404 0.596
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.404 0.596
M05.2 Rheumatoid vasculitis
0.000 0.404 0.596
M05.1 Rheumatoid lung disease
0.000 0.404 0.596
M05.0 Felty's syndrome
0.000 0.404 0.596
G37.5 Concentric sclerosis [Balo]
0.595 0.405 0.000
G37.4 Subacute necrotising myelitis
0.595 0.405 0.000
G37.2 Central pontine myelinolysis
0.595 0.405 0.000
G37.1 Central demyelination of corpus callosum
0.595 0.405 0.000
G37.0 Diffuse sclerosis
0.595 0.405 0.000
E85 Amyloidosis
0.001 0.407 0.592
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.409 0.591
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.411 0.589
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.411 0.589
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.411 0.589
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.411 0.589
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.411 0.589
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.411 0.589
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.411 0.589
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.411 0.589
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.427 0.573
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.427 0.573
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.427 0.573
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.427 0.573
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.427 0.573
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.427 0.573
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.427 0.573
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.427 0.573
E87.7 Fluid overload
0.000 0.429 0.571
E78.8 Other disorders of lipoprotein metabolism
0.000 0.432 0.567
E05.9 Thyrotoxicosis, unspecified
0.000 0.434 0.566
K51.0 Ulcerative (chronic) enterocolitis
0.564 0.436 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.439 0.561
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.442 0.558
E80.4 Gilbert's syndrome
0.000 0.445 0.555
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.457 0.543
E83.4 Disorders of magnesium metabolism
0.529 0.462 0.010
E11.3 With ophthalmic complications
0.000 0.464 0.536
M10 Gout
0.000 0.468 0.532
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.470 0.530
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.470 0.530
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.470 0.530
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.470 0.530
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.470 0.530
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.470 0.530
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.470 0.530
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.470 0.530
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.470 0.530
M07.6 Other enteropathic arthropathies
0.000 0.473 0.526
M07.5 Arthropathy in ulcerative colitis
0.000 0.473 0.526
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.473 0.526
M07.2 Psoriatic spondylitis
0.000 0.473 0.526
M07.1 Arthritis mutilans
0.000 0.473 0.526
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.473 0.526
M06.34 Rheumatoid nodule (Hand)
0.000 0.474 0.526
E80.7 Disorder of bilirubin metabolism, unspecified
0.001 0.476 0.523
E80.6 Other disorders of bilirubin metabolism
0.001 0.476 0.523
E80.5 Crigler-Najjar syndrome
0.001 0.476 0.523
E80.3 Defects of catalase and peroxydase
0.001 0.476 0.523
E80.2 Other porphyria
0.001 0.476 0.523
E80.1 Porphyria cutanea tarda
0.001 0.476 0.523
E80.0 Hereditary erythropoietic porphyria
0.001 0.476 0.523
E61 Deficiency of other nutrient elements
0.000 0.476 0.523
E46 Unspecified protein-energy malnutrition
0.000 0.478 0.522
E05.8 Other thyrotoxicosis
0.000 0.481 0.519
E05.5 Thyroid crisis or storm
0.000 0.481 0.519
E05.4 Thyrotoxicosis factitia
0.000 0.481 0.519
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.481 0.519
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.481 0.519
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.483 0.517
E45 Retarded development following protein-energy malnutrition
0.000 0.483 0.517
E43 Unspecified severe protein-energy malnutrition
0.000 0.483 0.517
E42 Marasmic kwashiorkor
0.000 0.483 0.517
E41 Nutritional marasmus
0.000 0.483 0.517
E40 Kwashiorkor
0.000 0.483 0.517
E87.0 Hyperosmolality and hypernatraemia
0.000 0.485 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
K51.4 Pseudopolyposis of colon
0.513 0.487 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.001 0.491 0.508
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.497 0.503
M06.38 Rheumatoid nodule (Other)
0.000 0.497 0.503
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.497 0.503
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.497 0.503
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.497 0.503
M06.33 Rheumatoid nodule (Forearm)
0.000 0.497 0.503
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.497 0.503
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.497 0.503
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.497 0.503
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.498 0.501
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.498 0.501
E70.3 Albinism
0.001 0.498 0.501
E70.2 Disorders of tyrosine metabolism
0.001 0.498 0.501
E70.1 Other hyperphenylalaninaemias
0.001 0.498 0.501
E70.0 Classical phenylketonuria
0.001 0.498 0.501
E71.3 Disorders of fatty-acid metabolism
0.001 0.498 0.501
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.498 0.501
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.498 0.501
E71.0 Maple-syrup-urine disease
0.001 0.498 0.501
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.498 0.501
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.498 0.501
E72.5 Disorders of glycine metabolism
0.001 0.498 0.501
E72.4 Disorders of ornithine metabolism
0.001 0.498 0.501
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.498 0.501
E72.2 Disorders of urea cycle metabolism
0.001 0.498 0.501
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.498 0.501
E72.0 Disorders of amino-acid transport
0.001 0.498 0.501
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.498 0.501
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.498 0.501
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.498 0.501
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.498 0.501
E74.2 Disorders of galactose metabolism
0.001 0.498 0.501
E74.1 Disorders of fructose metabolism
0.001 0.498 0.501
E74.0 Glycogen storage disease
0.001 0.498 0.501
E75.6 Lipid storage disorder, unspecified
0.001 0.498 0.501
E75.5 Other lipid storage disorders
0.001 0.498 0.501
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.498 0.501
E75.3 Sphingolipidosis, unspecified
0.001 0.498 0.501
E75.2 Other sphingolipidosis
0.001 0.498 0.501
E75.1 Other gangliosidosis
0.001 0.498 0.501
E75.0 GM2 gangliosidosis
0.001 0.498 0.501
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.498 0.501
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.498 0.501
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.498 0.501
E76.2 Other mucopolysaccharidoses
0.001 0.498 0.501
E76.1 Mucopolysaccharidosis, type II
0.001 0.498 0.501
E76.0 Mucopolysaccharidosis, type I
0.001 0.498 0.501
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.498 0.501
E77.8 Other disorders of glycoprotein metabolism
0.001 0.498 0.501
E77.1 Defects in glycoprotein degradation
0.001 0.498 0.501
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.498 0.501
E84.9 Cystic fibrosis, unspecified
0.001 0.498 0.501
E84.8 Cystic fibrosis with other manifestations
0.001 0.498 0.501
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.498 0.501
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.498 0.501
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.505 0.495
E07.8 Other specified disorders of thyroid
0.000 0.506 0.494
E07.1 Dyshormogenetic goitre
0.000 0.508 0.492
E07.0 Hypersecretion of calcitonin
0.000 0.508 0.492
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.509 0.491
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.514 0.486
M06.18 Adult-onset Still's disease (Other)
0.000 0.514 0.486
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.514 0.486
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.514 0.486
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.514 0.486
M06.14 Adult-onset Still's disease (Hand)
0.000 0.514 0.486
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.514 0.486
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.514 0.486
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.514 0.486
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.514 0.486
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.514 0.486
M06.28 Rheumatoid bursitis (Other)
0.000 0.514 0.486
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.514 0.486
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.514 0.486
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.514 0.486
M06.24 Rheumatoid bursitis (Hand)
0.000 0.514 0.486
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.514 0.486
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.514 0.486
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.514 0.486
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.514 0.486
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.514 0.486
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.514 0.486
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.514 0.486
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.514 0.486
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.514 0.486
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.514 0.486
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.514 0.486
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.514 0.486
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.514 0.486
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.514 0.486
M14.6 Neuropathic arthropathy
0.000 0.515 0.485
E06.9 Thyroiditis, unspecified
0.000 0.518 0.482
M07.38 Other psoriatic arthropathies (Other)
0.000 0.531 0.469
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.531 0.469
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.531 0.469
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.531 0.469
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.531 0.469
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.531 0.469
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.531 0.469
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.531 0.469
E88.9 Metabolic disorder, unspecified
0.001 0.531 0.468
E88.8 Other specified metabolic disorders
0.001 0.531 0.468
E88.3 Tumour lysis syndrome
0.001 0.531 0.468
E88.2 Lipomatosis, not elsewhere classified
0.001 0.531 0.468
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.531 0.468
E07.9 Disorder of thyroid, unspecified
0.000 0.542 0.458
E61.1 Iron deficiency
0.000 0.543 0.457
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.549 0.451
E73.8 Other lactose intolerance
0.001 0.549 0.450
E73.1 Secondary lactase deficiency
0.001 0.549 0.450
E73.0 Congenital lactase deficiency
0.001 0.549 0.450
M11.2 Other chondrocalcinosis
0.000 0.551 0.449
E87.2 Acidosis
0.000 0.553 0.447
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.554 0.445
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.554 0.445
E79.1 Lesch-Nyhan syndrome
0.001 0.554 0.445
E65-E68 Obesity and other hyperalimentation
0.000 0.557 0.443
G36.9 Acute disseminated demyelination, unspecified
0.442 0.558 0.000
G36.8 Other specified acute disseminated demyelination
0.442 0.558 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.442 0.558 0.000
G36.0 Neuromyelitis optica [Devic]
0.442 0.558 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.558 0.442
E63 Other nutritional deficiencies
0.000 0.558 0.442
E56 Other vitamin deficiencies
0.000 0.558 0.442
E51 Thiamine deficiency
0.000 0.558 0.442
E50 Vitamin A deficiency
0.000 0.558 0.442
E60 Dietary zinc deficiency
0.000 0.558 0.442
E59 Dietary selenium deficiency
0.000 0.558 0.442
E58 Dietary calcium deficiency
0.000 0.558 0.442
E54 Ascorbic acid deficiency
0.000 0.558 0.442
E52 Niacin deficiency [pellagra]
0.000 0.558 0.442
M11.9 Crystal arthropathy, unspecified
0.000 0.559 0.441
M11.8 Other specified crystal arthropathies
0.000 0.559 0.441
M11.1 Familial chondrocalcinosis
0.000 0.559 0.441
M11.0 Hydroxyapatite deposition disease
0.000 0.559 0.441
E87.4 Mixed disorder of acid-base balance
0.000 0.563 0.437
M08.9 Juvenile arthritis, unspecified
0.000 0.565 0.435
M08.8 Other juvenile arthritis
0.000 0.565 0.435
M08.4 Pauciarticular juvenile arthritis
0.000 0.565 0.435
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.565 0.435
M08.2 Juvenile arthritis with systemic onset
0.000 0.565 0.435
M08.1 Juvenile ankylosing spondylitis
0.000 0.565 0.435
M08.0 Juvenile rheumatoid arthritis
0.000 0.565 0.435
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.565 0.435
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.565 0.435
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.565 0.435
M09.0 Juvenile arthritis in psoriasis
0.000 0.565 0.435
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.565 0.435
M12.5 Traumatic arthropathy
0.000 0.565 0.435
M12.4 Intermittent hydrarthrosis
0.000 0.565 0.435
M12.3 Palindromic rheumatism
0.000 0.565 0.435
M12.2 Villonodular synovitis (pigmented)
0.000 0.565 0.435
M12.1 Kaschin-Beck disease
0.000 0.565 0.435
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.565 0.435
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.567 0.433
M14.4 Arthropathy in amyloidosis
0.000 0.567 0.433
M14.3 Lipoid dermatoarthritis
0.000 0.567 0.433
M14.2 Diabetic arthropathy
0.000 0.567 0.433
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.567 0.433
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.567 0.433
M05.09 Felty's syndrome (Site unspecified)
0.000 0.572 0.428
M05.08 Felty's syndrome (Other)
0.000 0.572 0.428
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.572 0.428
M05.06 Felty's syndrome (Lower leg)
0.000 0.572 0.428
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.572 0.428
M05.04 Felty's syndrome (Hand)
0.000 0.572 0.428
M05.03 Felty's syndrome (Forearm)
0.000 0.572 0.428
M05.02 Felty's syndrome (Upper arm)
0.000 0.572 0.428
M05.01 Felty's syndrome (Shoulder region)
0.000 0.572 0.428
M05.00 Felty's syndrome (Multiple sites)
0.000 0.572 0.428
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.572 0.428
M05.18 Rheumatoid lung disease (Other)
0.000 0.572 0.428
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.572 0.428
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.572 0.428
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.572 0.428
M05.14 Rheumatoid lung disease (Hand)
0.000 0.572 0.428
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.572 0.428
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.572 0.428
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.572 0.428
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.572 0.428
M05.29 Rheumatoid vasculitis (Site unspecified)
0.000 0.572 0.428
M05.28 Rheumatoid vasculitis (Other)
0.000 0.572 0.428
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.000 0.572 0.428
M05.26 Rheumatoid vasculitis (Lower leg)
0.000 0.572 0.428
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.000 0.572 0.428
M05.24 Rheumatoid vasculitis (Hand)
0.000 0.572 0.428
M05.23 Rheumatoid vasculitis (Forearm)
0.000 0.572 0.428
M05.22 Rheumatoid vasculitis (Upper arm)
0.000 0.572 0.428
M05.21 Rheumatoid vasculitis (Shoulder region)
0.000 0.572 0.428
M05.20 Rheumatoid vasculitis (Multiple sites)
0.000 0.572 0.428
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.572 0.428
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.572 0.428
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.572 0.428
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.572 0.428
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.572 0.428
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.572 0.428
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.572 0.428
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.572 0.428
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.572 0.428
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.572 0.428
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.572 0.428
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.572 0.428
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.572 0.428
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.572 0.428
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.572 0.428
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.572 0.428
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.572 0.428
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.572 0.428
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.572 0.428
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.572 0.428
E85.8 Other amyloidosis
0.001 0.575 0.424
E85.3 Secondary systemic amyloidosis
0.001 0.575 0.424
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.575 0.424
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.575 0.424
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.575 0.424
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.001 0.578 0.422
E87.3 Alkalosis
0.000 0.582 0.418
E20-E35 Disorders of other endocrine glands
0.000 0.587 0.413
E85.9 Amyloidosis, unspecified
0.001 0.588 0.411
E89.3 Postprocedural hypopituitarism
0.000 0.599 0.401
E04 Other non-toxic goitre
0.000 0.612 0.388
M10.4 Other secondary gout
0.000 0.619 0.381
M10.3 Gout due to impairment of renal function
0.000 0.619 0.381
M10.2 Drug-induced gout
0.000 0.619 0.381
M10.1 Lead-induced gout
0.000 0.619 0.381
E73.9 Lactose intolerance, unspecified
0.001 0.621 0.378
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.000 0.622 0.377
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.000 0.622 0.377
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.000 0.622 0.377
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.000 0.622 0.377
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.000 0.622 0.377
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.000 0.622 0.377
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.000 0.622 0.377
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.000 0.622 0.377
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.000 0.622 0.377
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.000 0.622 0.377
M07.19 Arthritis mutilans (Site unspecified)
0.000 0.622 0.377
M07.18 Arthritis mutilans (Other)
0.000 0.622 0.377
M07.17 Arthritis mutilans (Ankle and foot)
0.000 0.622 0.377
M07.16 Arthritis mutilans (Lower leg)
0.000 0.622 0.377
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.000 0.622 0.377
M07.14 Arthritis mutilans (Hand)
0.000 0.622 0.377
M07.13 Arthritis mutilans (Forearm)
0.000 0.622 0.377
M07.12 Arthritis mutilans (Upper arm)
0.000 0.622 0.377
M07.11 Arthritis mutilans (Shoulder region)
0.000 0.622 0.377

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

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