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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3129924
log Bayes Factor = 114.495
Chromosome 6   position 32,333,299  (GRCh37) Explore rs3129924 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
G50-G59 Nerve, nerve root and plexus disorders
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
G56.0 Carpal tunnel syndrome
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
G56 Mononeuropathies of upper limb
1.000 0.000 0.000
L40-L45 Papulosquamous disorders
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
H36.0 Diabetic retinopathy
1.000 0.000 0.000
H36 Retinal disorders in diseases classified elsewhere
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
1.000 0.000 0.000
E27 Other disorders of adrenal gland
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
E27.1 Primary adrenocortical insufficiency
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
E10.1 With ketoacidosis
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
D64 Other anaemias
0.999 0.001 0.000
D64.9 Anaemia, unspecified
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
C15-C26 Malignant neoplasms of digestive organs
0.999 0.001 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.998 0.002 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.998 0.002 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.003 0.997
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.003 0.997
C91 Lymphoid leukaemia
0.997 0.003 0.000
D70 Agranulocytosis
0.997 0.003 0.000
G51 Facial nerve disorders
0.996 0.004 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.996 0.004 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.996 0.004 0.000
C83.3 Large cell (diffuse)
0.994 0.006 0.000
E11.9 Without complications
0.991 0.009 0.000
D50-D53 Nutritional anaemias
0.991 0.009 0.000
E14.3 With ophthalmic complications
0.991 0.009 0.000
G51.0 Bell's palsy
0.990 0.010 0.000
M20.1 Hallux valgus (acquired)
0.000 0.010 0.990
B35-B49 Mycoses
0.990 0.010 0.000
C91.1 Chronic lymphocytic leukaemia
0.990 0.010 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.990 0.010 0.000
H34 Retinal vascular occlusions
0.989 0.011 0.000
N00-N08 Glomerular diseases
0.989 0.011 0.000
N04 Nephrotic syndrome
0.988 0.012 0.000
B37 Candidiasis
0.988 0.012 0.000
N04.9 Unspecified
0.987 0.013 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.985 0.015 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.985 0.015 0.000
M06 Other rheumatoid arthritis
0.005 0.016 0.979
C20 Malignant neoplasm of rectum
0.983 0.017 0.000
M05-M14 Inflammatory polyarthropathies
0.248 0.017 0.735
E70-E90 Metabolic disorders
0.982 0.018 0.000
B37.8 Candidiasis of other sites
0.981 0.019 0.000
L50-L54 Urticaria and erythema
0.980 0.020 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.980 0.020 0.000
C18 Malignant neoplasm of colon
0.980 0.020 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.976 0.024 0.000
E89.0 Postprocedural hypothyroidism
0.976 0.024 0.000
H34.8 Other retinal vascular occlusions
0.976 0.024 0.000
A30-A49 Other bacterial diseases
0.974 0.026 0.000
C85.1 B-cell lymphoma, unspecified
0.973 0.027 0.000
E10.2 With renal complications
0.972 0.028 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.972 0.028 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.970 0.030 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.969 0.030 0.001
A41 Other septicaemia
0.968 0.032 0.000
D80-D89 Certain disorders involving the immune mechanism
0.967 0.033 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.966 0.034 0.000
E11.3 With ophthalmic complications
0.965 0.035 0.000
L10-L14 Bullous disorders
0.964 0.036 0.000
A41.9 Septicaemia, unspecified
0.964 0.036 0.000
E50-E64 Other nutritional deficiencies
0.960 0.040 0.000
C18.7 Sigmoid colon
0.960 0.040 0.000
D50 Iron deficiency anaemia
0.956 0.044 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.955 0.045 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.955 0.045 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.953 0.047 0.000
N05 Unspecified nephritic syndrome
0.951 0.049 0.000
D50.9 Iron deficiency anaemia, unspecified
0.950 0.050 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.949 0.051 0.000
M60-M63 Disorders of muscles
0.946 0.053 0.000
E14.9 Without complications
0.946 0.054 0.000
L13 Other bullous disorders
0.946 0.054 0.000
L52 Erythema nodosum
0.945 0.055 0.000
H33 Retinal detachments and breaks
0.943 0.057 0.000
E11.1 With ketoacidosis
0.940 0.060 0.000
C18.9 Colon, unspecified
0.937 0.063 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.064 0.936
D61 Other aplastic anaemias
0.935 0.065 0.000
M15-M19 Arthrosis
0.934 0.066 0.000
H33.3 Retinal breaks without detachment
0.934 0.066 0.000
L13.0 Dermatitis herpetiformis
0.933 0.067 0.000
D51 Vitamin B12 deficiency anaemia
0.933 0.067 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.931 0.069 0.000
C34 Malignant neoplasm of bronchus and lung
0.931 0.069 0.000
M06.3 Rheumatoid nodule
0.002 0.072 0.926
H05 Disorders of orbit
0.926 0.074 0.000
E10.4 With neurological complications
0.924 0.076 0.000
M18 Arthrosis of first carpometacarpal joint
0.922 0.078 0.000
B37.9 Candidiasis, unspecified
0.922 0.078 0.000
E21.3 Hyperparathyroidism, unspecified
0.921 0.079 0.000
E53 Deficiency of other B group vitamins
0.917 0.083 0.000
Q43 Other congenital malformations of intestine
0.917 0.083 0.000
M62 Other disorders of muscle
0.915 0.084 0.000
H06.2 Dysthyroid exophthalmos
0.915 0.085 0.000
M20 Acquired deformities of fingers and toes
0.000 0.088 0.912
C04 Malignant neoplasm of floor of mouth
0.911 0.089 0.000
E28 Ovarian dysfunction
0.909 0.091 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.091 0.909
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.907 0.093 0.000
B25-B34 Other viral diseases
0.905 0.095 0.000
E11.2 With renal complications
0.905 0.095 0.000
C34.3 Lower lobe, bronchus or lung
0.904 0.096 0.000
D73 Diseases of spleen
0.904 0.096 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.903 0.097 0.000
C91.9 Lymphoid leukaemia, unspecified
0.896 0.104 0.000
E53.8 Deficiency of other specified B group vitamins
0.895 0.105 0.000
N05.2 Diffuse membranous glomerulonephritis
0.895 0.105 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.892 0.108 0.000
Chapter XIV Diseases of the genitourinary system
0.890 0.110 0.000
E88 Other metabolic disorders
0.888 0.112 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.888 0.112 0.000
G51.9 Disorder of facial nerve, unspecified
0.887 0.113 0.000
D61.9 Aplastic anaemia, unspecified
0.887 0.113 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.887 0.113 0.000
M06.34 Rheumatoid nodule (Hand)
0.001 0.115 0.884
M05 Seropositive rheumatoid arthritis
0.114 0.119 0.768
H05.2 Exophthalmic conditions
0.881 0.119 0.000
B15-B19 Viral hepatitis
0.879 0.121 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.878 0.122 0.000
E14.8 With unspecified complications
0.877 0.123 0.000
M62.8 Other specified disorders of muscle
0.876 0.124 0.000
D55-D59 Haemolytic anaemias
0.874 0.126 0.000
M86-M90 Other osteopathies
0.872 0.127 0.000
C81 Hodgkin's disease
0.869 0.131 0.000
M15 Polyarthrosis
0.868 0.132 0.000
E07 Other disorders of thyroid
0.868 0.132 0.000
C18.0 Caecum
0.868 0.132 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.133 0.867
M18.1 Other primary arthrosis of first carpometacarpal joint
0.867 0.133 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.867 0.133 0.000
D86 Sarcoidosis
0.866 0.134 0.000
L53 Other erythematous conditions
0.865 0.135 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.864 0.136 0.000
C15 Malignant neoplasm of oesophagus
0.863 0.137 0.000
D69 Purpura and other haemorrhagic conditions
0.863 0.137 0.000
M80-M85 Disorders of bone density and structure
0.862 0.138 0.000
B07 Viral warts
0.860 0.140 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.858 0.142 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.855 0.145 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.854 0.146 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.852 0.148 0.000
D80 Immunodeficiency with predominantly antibody defects
0.851 0.149 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.851 0.149 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.851 0.149 0.000
N17-N19 Renal failure
0.848 0.152 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.846 0.154 0.000
E78.2 Mixed hyperlipidaemia
0.846 0.154 0.000
B00 Herpesviral [herpes simplex] infections
0.845 0.155 0.000
H43-H45 Disorders of vitreous body and globe
0.845 0.155 0.000
G30-G32 Other degenerative diseases of the nervous system
0.844 0.156 0.000
D73.5 Infarction of spleen
0.844 0.156 0.000
H30 Chorioretinal inflammation
0.841 0.159 0.000
Q60-Q64 Congenital malformations of the urinary system
0.839 0.161 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.837 0.163 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.018 0.169 0.813
A41.3 Septicaemia due to Haemophilus influenzae
0.829 0.171 0.000
E11.8 With unspecified complications
0.828 0.172 0.000
E28.2 Polycystic ovarian syndrome
0.828 0.172 0.000
G56.4 Causalgia
0.827 0.173 0.000
E10.7 With multiple complications
0.826 0.174 0.000
G40-G47 Episodic and paroxysmal disorders
0.826 0.174 0.000
E07.8 Other specified disorders of thyroid
0.823 0.176 0.000
E10.0 With coma
0.823 0.177 0.000
E14.1 With ketoacidosis
0.822 0.178 0.000
N05.1 Focal and segmental glomerular lesions
0.822 0.178 0.000
L40.3 Pustulosis palmaris et plantaris
0.822 0.178 0.000
C04.9 Floor of mouth, unspecified
0.821 0.179 0.000
B37.0 Candidal stomatitis
0.821 0.179 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.821 0.179 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.818 0.182 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.817 0.183 0.000
H34.2 Other retinal artery occlusions
0.817 0.183 0.000
M20.4 Other hammer toe(s) (acquired)
0.000 0.184 0.816
N18 Chronic renal failure
0.816 0.184 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.184 0.816
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.001 0.184 0.815
H33.4 Traction detachment of retina
0.816 0.184 0.000
C12 Malignant neoplasm of pyriform sinus
0.814 0.186 0.000
E21.0 Primary hyperparathyroidism
0.814 0.186 0.000
Q00-Q07 Congenital malformations of the nervous system
0.813 0.187 0.000
G56.1 Other lesions of median nerve
0.813 0.187 0.000
L44 Other papulosquamous disorders
0.813 0.187 0.000
H05.0 Acute inflammation of orbit
0.812 0.188 0.000
Q43.0 Meckel's diverticulum
0.811 0.189 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.811 0.189 0.000
E11.5 With peripheral circulatory complications
0.810 0.190 0.000
B34 Viral infection of unspecified site
0.809 0.191 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.807 0.193 0.000
C25 Malignant neoplasm of pancreas
0.806 0.194 0.000
N04.2 Diffuse membranous glomerulonephritis
0.806 0.194 0.000
M86 Osteomyelitis
0.806 0.194 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.195 0.805
M60 Myositis
0.804 0.195 0.000
N04.1 Focal and segmental glomerular lesions
0.804 0.196 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.803 0.197 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.802 0.198 0.000
C23 Malignant neoplasm of gallbladder
0.802 0.198 0.000
D86.3 Sarcoidosis of skin
0.802 0.198 0.000
M20-M25 Other joint disorders
0.799 0.200 0.001
D69.4 Other primary thrombocytopenia
0.800 0.200 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.800 0.200 0.000
C07 Malignant neoplasm of parotid gland
0.799 0.201 0.000
C13 Malignant neoplasm of hypopharynx
0.799 0.201 0.000
N18.9 Chronic renal failure, unspecified
0.798 0.202 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.003 0.202 0.795
D59 Acquired haemolytic anaemia
0.798 0.202 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.796 0.203 0.000
M80 Osteoporosis with pathological fracture
0.796 0.204 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.204 0.796
C40-C41 Malignant neoplasms of bone and articular cartilage
0.796 0.204 0.000
E27.8 Other specified disorders of adrenal gland
0.796 0.204 0.000
C78.0 Secondary malignant neoplasm of lung
0.796 0.204 0.000
E10.8 With unspecified complications
0.795 0.205 0.000
E31 Polyglandular dysfunction
0.795 0.205 0.000
M62.81 Other specified disorders of muscle (Shoulder region)
0.794 0.206 0.000
M35.0 Sicca syndrome [Sjogren]
0.794 0.206 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.794 0.206 0.000
M35 Other systemic involvement of connective tissue
0.793 0.207 0.000
H43 Disorders of vitreous body
0.793 0.207 0.000
M20.5 Other deformities of toe(s) (acquired)
0.000 0.208 0.792
B37.7 Candidal septicaemia
0.792 0.208 0.000
A63.0 Anogenital (venereal) warts
0.790 0.210 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.790 0.210 0.000
C34.2 Middle lobe, bronchus or lung
0.788 0.212 0.000
C02.9 Tongue, unspecified
0.787 0.213 0.000
C04.0 Anterior floor of mouth
0.785 0.215 0.000
G51.3 Clonic hemifacial spasm
0.785 0.215 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.784 0.216 0.000
C83.7 Burkitt's tumour
0.783 0.217 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.782 0.218 0.000
C88 Malignant immunoproliferative diseases
0.781 0.219 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.780 0.220 0.000
E51 Thiamine deficiency
0.780 0.220 0.000
L40.1 Generalised pustular psoriasis
0.780 0.220 0.000
E14.2 Withrenal complications
0.777 0.223 0.000
E10.5 With peripheral circulatory complications
0.776 0.224 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.775 0.225 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.775 0.225 0.000
N18.3 Chronic kidney disease, stage 3
0.774 0.226 0.000
B25 Cytomegaloviral disease
0.774 0.226 0.000
B94 Sequelae of other and unspecified infectious and parasitic diseases
0.773 0.227 0.000
E24 Cushing's syndrome
0.772 0.228 0.000
G11 Hereditary ataxia
0.771 0.229 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.232 0.768
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.767 0.233 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.766 0.234 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.235 0.765
C15.4 Middle third of oesophagus
0.765 0.235 0.000
C84.5 Other and unspecified T-cell lymphomas
0.765 0.235 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.765 0.235 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.763 0.237 0.000
D52 Folate deficiency anaemia
0.763 0.237 0.000
M06.0 Seronegative rheumatoid arthritis
0.002 0.237 0.761
E16.1 Other hypoglycaemia
0.762 0.237 0.000
Q43.3 Congenital malformations of intestinal fixation
0.762 0.238 0.000
C83.1 Small cleaved cell (diffuse)
0.762 0.238 0.000
C51-C58 Malignant neoplasms of female genital organs
0.762 0.238 0.000
E40-E46 Malnutrition
0.762 0.238 0.000
B02 Zoster [herpes zoster]
0.762 0.238 0.000
D62 Acute posthaemorrhagic anaemia
0.762 0.238 0.000
L53.0 Toxic erythema
0.761 0.239 0.000
M06.4 Inflammatory polyarthropathy
0.003 0.240 0.757
H33.1 Retinoschisis and retinal cysts
0.760 0.240 0.000
M00-M03 Infectious arthropathies
0.760 0.240 0.001
D82 Immunodeficiency associated with other major defects
0.760 0.240 0.000
C34.8 Overlapping lesion of bronchus and lung
0.759 0.241 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.758 0.242 0.000
E14.5 With peripheral circulatory complications
0.758 0.242 0.000
N17 Acute renal failure
0.757 0.243 0.000
C80 Malignant neoplasm without specification of site
0.757 0.243 0.000
B36 Other superficial mycoses
0.756 0.244 0.000
G40 Epilepsy
0.756 0.244 0.000
E73 Lactose intolerance
0.755 0.245 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.755 0.245 0.000
E78.4 Other hyperlipidaemia
0.755 0.245 0.000
C18.6 Descending colon
0.755 0.245 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.754 0.246 0.000
M15.4 Erosive (osteo)arthrosis
0.754 0.246 0.000
D86.9 Sarcoidosis, unspecified
0.753 0.247 0.000
D69.6 Thrombocytopenia, unspecified
0.753 0.247 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.752 0.248 0.000
Q44.6 Cystic disease of liver
0.752 0.248 0.000
H43.1 Vitreous haemorrhage
0.752 0.248 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.749 0.250 0.000
C38.4 Pleura
0.749 0.251 0.000
Chapter VIII Diseases of the ear and mastoid process
0.748 0.252 0.000
E21.2 Other hyperparathyroidism
0.747 0.253 0.000
B00.9 Herpesviral infection, unspecified
0.747 0.253 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.746 0.254 0.000
C25.9 Pancreas, unspecified
0.746 0.254 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.745 0.255 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.745 0.255 0.000
L40.0 Psoriasis vulgaris
0.744 0.256 0.000
Q80-Q89 Other congenital malformations
0.743 0.257 0.000
D50.1 Sideropenic dysphagia
0.742 0.258 0.000
D73.1 Hypersplenism
0.741 0.259 0.000
E27.9 Disorder of adrenal gland, unspecified
0.741 0.259 0.000
E78.1 Pure hyperglyceridaemia
0.741 0.259 0.000
C91.5 Adult T-cell leukaemia
0.741 0.259 0.000
D69.2 Other nonthrombocytopenic purpura
0.740 0.260 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.739 0.261 0.000
B18 Chronic viral hepatitis
0.739 0.261 0.000
M20.3 Other deformity of hallux (acquired)
0.000 0.262 0.738
E21.5 Disorder of parathyroid gland, unspecified
0.736 0.264 0.000
H46 Optic neuritis
0.736 0.264 0.000
Q50-Q56 Congenital malformations of genital organs
0.736 0.264 0.000
E20 Hypoparathyroidism
0.736 0.264 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.735 0.265 0.000
B37.1 Pulmonary candidiasis
0.734 0.266 0.000
E78.6 Lipoprotein deficiency
0.734 0.266 0.000
C56 Malignant neoplasm of ovary
0.733 0.267 0.000
E14.4 With neurological complications
0.731 0.269 0.000
C81.1 Nodular sclerosis
0.730 0.270 0.000
L20-L30 Dermatitis and eczema
0.730 0.270 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.730 0.270 0.000
B91 Sequelae of poliomyelitis
0.729 0.271 0.000
C03 Malignant neoplasm of gum
0.728 0.272 0.000
E27.2 Addisonian crisis
0.728 0.272 0.000
E06 Thyroiditis
0.728 0.272 0.000
B01 Varicella [chickenpox]
0.728 0.272 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.727 0.273 0.000
H30.9 Chorioretinal inflammation, unspecified
0.727 0.273 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.726 0.274 0.000
E55 Vitamin D deficiency
0.725 0.275 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.724 0.275 0.000
B16 Acute hepatitis B
0.724 0.276 0.000
C91.0 Acute lymphoblastic leukaemia
0.724 0.276 0.000
G70-G73 Diseases of myoneural junction and muscle
0.724 0.276 0.000
D83 Common variable immunodeficiency
0.722 0.278 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.722 0.278 0.000
N05.8 Other
0.721 0.278 0.000
M87 Osteonecrosis
0.721 0.279 0.000
M86.9 Osteomyelitis, unspecified
0.721 0.279 0.000
L53.9 Erythematous condition, unspecified
0.718 0.282 0.000
E10.6 With other specified complications
0.718 0.282 0.000
H34.9 Retinal vascular occlusion, unspecified
0.718 0.282 0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.717 0.283 0.000
C94 Other leukaemias of specified cell type
0.717 0.283 0.000
C93 Monocytic leukaemia
0.717 0.283 0.000
C86 Other specified types of T/NK-cell lymphoma
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.717 0.283 0.000
E32 Diseases of thymus
0.717 0.283 0.000
E30 Disorders of puberty, not elsewhere classified
0.717 0.283 0.000
E25 Adrenogenital disorders
0.717 0.283 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
L41 Parapsoriasis
0.717 0.283 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.717 0.283 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.717 0.283 0.000
C85.0 Lymphosarcoma
0.717 0.283 0.000
E27.5 Adrenomedullary hyperfunction
0.717 0.283 0.000
E27.0 Other adrenocortical overactivity
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
E14.7 With multiple complications
0.717 0.283 0.000
E14.0 With coma
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.717 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.717 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.717 0.283 0.000
E16.3 Increased secretion of glucagon
0.717 0.283 0.000
C18.1 Appendix
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.716 0.283 0.000
D64.3 Other sideroblastic anaemias
0.716 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.716 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.716 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.716 0.283 0.000
C38.3 Mediastinum, part unspecified
0.717 0.283 0.000
E88.2 Lipomatosis, not elsewhere classified
0.716 0.284 0.000
C05 Malignant neoplasm of palate
0.716 0.284 0.000
D74 Methaemoglobinaemia
0.716 0.284 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.716 0.284 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.716 0.284 0.000
E89.4 Postprocedural ovarian failure
0.715 0.285 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.715 0.285 0.000
C91.7 Other lymphoid leukaemia
0.715 0.285 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.715 0.285 0.000
C91.3 Prolymphocytic leukaemia
0.715 0.285 0.000
C91.2 Subacute lymphocytic leukaemia
0.715 0.285 0.000
G51.4 Facial myokymia
0.714 0.285 0.000
G51.2 Melkersson's syndrome
0.714 0.285 0.000
G51.1 Geniculate ganglionitis
0.714 0.285 0.000
C83.6 Undifferentiated (diffuse)
0.714 0.286 0.000
C83.5 Lymphoblastic (diffuse)
0.714 0.286 0.000
C83.4 Immunoblastic (diffuse)
0.714 0.286 0.000
C83.2 Mixed small and large cell (diffuse)
0.714 0.286 0.000
B34.9 Viral infection, unspecified
0.714 0.286 0.000
C34.0 Main bronchus
0.713 0.287 0.000
M60.9 Myositis, unspecified
0.713 0.287 0.000
L51 Erythema multiforme
0.713 0.287 0.000
H34.1 Central retinal artery occlusion
0.712 0.288 0.000
E74 Other disorders of carbohydrate metabolism
0.711 0.289 0.000
C81.2 Mixed cellularity
0.711 0.289 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.711 0.289 0.000
E23 Hypofunction and other disorders of pituitary gland
0.711 0.289 0.000
B48 Other mycoses, not elsewhere classified
0.710 0.290 0.000
B47 Mycetoma
0.710 0.290 0.000
B46 Zygomycosis
0.710 0.290 0.000
B45 Cryptococcosis
0.710 0.290 0.000
B43 Chromomycosis and phaeomycotic abscess
0.710 0.290 0.000
B42 Sporotrichosis
0.710 0.290 0.000
B41 Paracoccidioidomycosis
0.710 0.290 0.000
B40 Blastomycosis
0.710 0.290 0.000
B39 Histoplasmosis
0.710 0.290 0.000
B38 Coccidioidomycosis
0.710 0.290 0.000
C17 Malignant neoplasm of small intestine
0.710 0.290 0.000
G11.9 Hereditary ataxia, unspecified
0.709 0.291 0.000
H34.0 Transient retinal artery occlusion
0.709 0.291 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.709 0.291 0.000
N06 Isolated proteinuria with specified morphological lesion
0.709 0.291 0.000
N01 Rapidly progressive nephritic syndrome
0.709 0.291 0.000
N00 Acute nephritic syndrome
0.709 0.291 0.000
N04.8 Other
0.709 0.291 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.709 0.291 0.000
N04.6 Dense deposit disease
0.709 0.291 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.709 0.291 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.709 0.291 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.709 0.291 0.000
N04.0 Minor glomerular abnormality
0.709 0.291 0.000
B37.6 Candidal endocarditis
0.708 0.292 0.000
B37.5 Candidal meningitis
0.708 0.292 0.000
A46 Erysipelas
0.708 0.292 0.000
M24 Other specific joint derangements
0.708 0.292 0.000
C18.8 Overlapping lesion of colon
0.708 0.292 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.706 0.294 0.000
Q35-Q37 Cleft lip and cleft palate
0.706 0.294 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.706 0.294 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.706 0.294 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.706 0.294 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.706 0.294 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.706 0.294 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.706 0.294 0.000
E88.8 Other specified metabolic disorders
0.706 0.294 0.000
Q40 Other congenital malformations of upper alimentary tract
0.706 0.294 0.000
M06.8 Other specified rheumatoid arthritis
0.003 0.294 0.702
M06.2 Rheumatoid bursitis
0.003 0.294 0.702
M06.1 Adult-onset Still's disease
0.003 0.294 0.702
C84.8 Cutaneous T-cell lymphoma, unspecified
0.705 0.295 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.178 0.295 0.527
M08 Juvenile arthritis
0.178 0.295 0.527
E84 Cystic fibrosis
0.704 0.296 0.000
E77 Disorders of glycoprotein metabolism
0.704 0.296 0.000
E76 Disorders of glycosaminoglycan metabolism
0.704 0.296 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.704 0.296 0.000
E72 Other disorders of amino-acid metabolism
0.704 0.296 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.704 0.296 0.000
E70 Disorders of aromatic amino-acid metabolism
0.704 0.296 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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