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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130139
log Bayes Factor = 67.4405
Chromosome 6   position 30,357,176  (GRCh37) Explore rs3130139 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10.3 With ophthalmic complications
0.998 0.002 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.997 0.003 0.000
E05.9 Thyrotoxicosis, unspecified
0.997 0.003 0.000
E10.2 With renal complications
0.962 0.038 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.962 0.038 0.000
E20-E35 Disorders of other endocrine glands
0.945 0.055 0.000
E10.4 With neurological complications
0.935 0.065 0.000
E16 Other disorders of pancreatic internal secretion
0.934 0.066 0.000
E27 Other disorders of adrenal gland
0.916 0.084 0.000
E27.1 Primary adrenocortical insufficiency
0.912 0.088 0.000
E14 Unspecified diabetes mellitus
0.902 0.098 0.000
E10.1 With ketoacidosis
0.885 0.115 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.857 0.143 0.000
E13 Other specified diabetes mellitus
0.843 0.157 0.000
E16.2 Hypoglycaemia, unspecified
0.842 0.158 0.000
E14.3 With ophthalmic complications
0.822 0.178 0.000
K90 Intestinal malabsorption
0.815 0.185 0.000
E06 Thyroiditis
0.807 0.193 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.803 0.197 0.000
E31 Polyglandular dysfunction
0.788 0.212 0.000
E03.8 Other specified hypothyroidism
0.788 0.212 0.000
E10.8 With unspecified complications
0.780 0.220 0.000
E22 Hyperfunction of pituitary gland
0.770 0.230 0.000
E28 Ovarian dysfunction
0.760 0.240 0.000
E16.1 Other hypoglycaemia
0.746 0.254 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.742 0.258 0.000
E10.7 With multiple complications
0.733 0.267 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.729 0.271 0.000
E14.1 With ketoacidosis
0.724 0.276 0.000
E24 Cushing's syndrome
0.722 0.278 0.000
E14.6 With other specified complications
0.722 0.278 0.000
E14.2 Withrenal complications
0.720 0.280 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.715 0.285 0.000
E05.4 Thyrotoxicosis factitia
0.715 0.285 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.715 0.285 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.707 0.293 0.000
E14.8 With unspecified complications
0.701 0.299 0.000
E27.2 Addisonian crisis
0.695 0.305 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.690 0.310 0.000
E15 Nondiabetic hypoglycaemic coma
0.689 0.310 0.000
E13.3 With ophthalmic complications
0.689 0.311 0.000
E10.6 With other specified complications
0.688 0.312 0.000
E14.4 With neurological complications
0.687 0.313 0.000
E03.1 Congenital hypothyroidism without goitre
0.684 0.316 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.677 0.322 0.000
E32 Diseases of thymus
0.677 0.322 0.000
E30 Disorders of puberty, not elsewhere classified
0.677 0.322 0.000
E31.0 Autoimmune polyglandular failure
0.676 0.324 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.671 0.329 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.670 0.330 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.670 0.330 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.670 0.330 0.000
E16.4 Abnormal secretion of gastrin
0.670 0.330 0.000
E16.3 Increased secretion of glucagon
0.670 0.330 0.000
E13.9 Without complications
0.668 0.332 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.665 0.335 0.000
E06.5 Other chronic thyroiditis
0.660 0.340 0.000
E27.5 Adrenomedullary hyperfunction
0.657 0.343 0.000
E27.0 Other adrenocortical overactivity
0.657 0.343 0.000
E25 Adrenogenital disorders
0.656 0.343 0.000
E28.2 Polycystic ovarian syndrome
0.653 0.347 0.000
E05.8 Other thyrotoxicosis
0.651 0.348 0.000
K90.9 Intestinal malabsorption, unspecified
0.648 0.352 0.000
E14.7 With multiple complications
0.646 0.354 0.000
E14.0 With coma
0.646 0.354 0.000
E40-E46 Malnutrition
0.645 0.355 0.000
K90.8 Other intestinal malabsorption
0.641 0.359 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.639 0.361 0.000
E22.1 Hyperprolactinaemia
0.634 0.366 0.000
E10.0 With coma
0.632 0.368 0.000
E20 Hypoparathyroidism
0.629 0.371 0.000
E29 Testicular dysfunction
0.626 0.374 0.000
E06.3 Autoimmune thyroiditis
0.614 0.386 0.000
E50-E64 Other nutritional deficiencies
0.606 0.394 0.000
E13.8 With unspecified complications
0.604 0.396 0.000
E13.7 With multiple complications
0.604 0.396 0.000
E13.6 With other specified complications
0.604 0.396 0.000
E13.5 With peripheral circulatory complications
0.604 0.396 0.000
E13.4 With neurological complications
0.604 0.396 0.000
E13.2 With renal complications
0.604 0.396 0.000
E13.1 With ketoacidosis
0.604 0.396 0.000
E13.0 With coma
0.604 0.396 0.000
E14.5 With peripheral circulatory complications
0.597 0.403 0.000
E23 Hypofunction and other disorders of pituitary gland
0.591 0.409 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.590 0.410 0.000
E26 Hyperaldosteronism
0.588 0.412 0.000
K90.3 Pancreatic steatorrhoea
0.584 0.416 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.584 0.416 0.000
K90.1 Tropical sprue
0.584 0.416 0.000
E06.4 Drug-induced thyroiditis
0.579 0.421 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.579 0.421 0.000
E06.0 Acute thyroiditis
0.579 0.421 0.000
E10.5 With peripheral circulatory complications
0.577 0.423 0.000
E27.9 Disorder of adrenal gland, unspecified
0.572 0.428 0.000
E06.1 Subacute thyroiditis
0.568 0.432 0.000
E06.9 Thyroiditis, unspecified
0.567 0.432 0.000
E31.9 Polyglandular dysfunction, unspecified
0.565 0.435 0.000
E31.8 Other polyglandular dysfunction
0.565 0.435 0.000
E31.1 Polyglandular hyperfunction
0.565 0.435 0.000
E24.0 Pituitary-dependent Cushing's disease
0.561 0.438 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.552 0.448 0.000
E22.8 Other hyperfunction of pituitary gland
0.552 0.448 0.000
E24.2 Drug-induced Cushing's syndrome
0.546 0.454 0.000
E28.9 Ovarian dysfunction, unspecified
0.545 0.455 0.000
E28.8 Other ovarian dysfunction
0.545 0.455 0.000
E28.1 Androgen excess
0.545 0.455 0.000
E28.0 Oestrogen excess
0.545 0.455 0.000
E55 Vitamin D deficiency
0.545 0.455 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.517 0.482 0.000
E24.3 Ectopic ACTH syndrome
0.517 0.482 0.000
E24.1 Nelson's syndrome
0.517 0.482 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E07 Other disorders of thyroid
0.512 0.488 0.000
E24.8 Other Cushing's syndrome
0.509 0.491 0.000
E55.9 Vitamin D deficiency, unspecified
0.502 0.498 0.000
E28.3 Primary ovarian failure
0.495 0.505 0.000
E24.9 Cushing's syndrome, unspecified
0.495 0.505 0.000
E30.9 Disorder of puberty, unspecified
0.486 0.514 0.000
E30.8 Other disorders of puberty
0.486 0.514 0.000
E30.1 Precocious puberty
0.486 0.514 0.000
E30.0 Delayed puberty
0.486 0.514 0.000
E32.9 Disease of thymus, unspecified
0.486 0.514 0.000
E32.8 Other diseases of thymus
0.486 0.514 0.000
E32.1 Abscess of thymus
0.486 0.514 0.000
E32.0 Persistent hyperplasia of thymus
0.486 0.514 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.486 0.514 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.486 0.514 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.486 0.514 0.000
E21.3 Hyperparathyroidism, unspecified
0.477 0.523 0.000
E23.2 Diabetes insipidus
0.474 0.526 0.000
E25.9 Adrenogenital disorder, unspecified
0.471 0.529 0.000
E25.8 Other adrenogenital disorders
0.471 0.529 0.000
E21.2 Other hyperparathyroidism
0.470 0.530 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.462 0.538 0.000
E45 Retarded development following protein-energy malnutrition
0.462 0.538 0.000
E43 Unspecified severe protein-energy malnutrition
0.462 0.538 0.000
E42 Marasmic kwashiorkor
0.462 0.538 0.000
E41 Nutritional marasmus
0.462 0.538 0.000
E40 Kwashiorkor
0.462 0.538 0.000
E21.4 Other specified disorders of parathyroid gland
0.458 0.542 0.000
E20.8 Other hypoparathyroidism
0.451 0.549 0.000
E20.1 Pseudohypoparathyroidism
0.451 0.549 0.000
E20.0 Idiopathic hypoparathyroidism
0.451 0.549 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.450 0.550 0.000
E29.8 Other testicular dysfunction
0.449 0.551 0.000
E29.0 Testicular hyperfunction
0.449 0.551 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.446 0.554 0.000
E21.0 Primary hyperparathyroidism
0.445 0.555 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.440 0.560 0.000
E29.9 Testicular dysfunction, unspecified
0.439 0.560 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.435 0.565 0.000
E63 Other nutritional deficiencies
0.435 0.565 0.000
E50 Vitamin A deficiency
0.435 0.565 0.000
E60 Dietary zinc deficiency
0.435 0.565 0.000
E59 Dietary selenium deficiency
0.435 0.565 0.000
E52 Niacin deficiency [pellagra]
0.435 0.565 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.566 0.434
E58 Dietary calcium deficiency
0.432 0.568 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.423 0.576 0.000
E23.1 Drug-induced hypopituitarism
0.423 0.576 0.000
E26.8 Other hyperaldosteronism
0.421 0.578 0.000
E26.1 Secondary hyperaldosteronism
0.421 0.578 0.000
E51 Thiamine deficiency
0.421 0.579 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.580 0.420
E26.9 Hyperaldosteronism, unspecified
0.417 0.583 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.415 0.585 0.000
E34 Other endocrine disorders
0.410 0.589 0.001
E29.1 Testicular hypofunction
0.409 0.591 0.000
E54 Ascorbic acid deficiency
0.409 0.591 0.000
E56 Other vitamin deficiencies
0.408 0.592 0.000
E20.9 Hypoparathyroidism, unspecified
0.402 0.598 0.000
E07.8 Other specified disorders of thyroid
0.398 0.601 0.000
E23.0 Hypopituitarism
0.396 0.604 0.000
E23.7 Disorder of pituitary gland, unspecified
0.394 0.606 0.000
E55.0 Rickets, active
0.391 0.609 0.000
E46 Unspecified protein-energy malnutrition
0.390 0.610 0.000
E07.1 Dyshormogenetic goitre
0.367 0.633 0.000
E07.0 Hypersecretion of calcitonin
0.367 0.633 0.000
E27.8 Other specified disorders of adrenal gland
0.340 0.659 0.001
E26.0 Primary hyperaldosteronism
0.338 0.662 0.000
E44.1 Mild protein-energy malnutrition
0.331 0.668 0.000
E44.0 Moderate protein-energy malnutrition
0.331 0.668 0.000
E22.0 Acromegaly and pituitary gigantism
0.330 0.670 0.000
E23.6 Other disorders of pituitary gland
0.325 0.675 0.000
E50.9 Vitamin A deficiency, unspecified
0.312 0.688 0.000
E50.8 Other manifestations of vitamin A deficiency
0.312 0.688 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.312 0.688 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.312 0.688 0.000
E50.5 Vitamin A deficiency with night blindness
0.312 0.688 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.312 0.688 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.312 0.688 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.312 0.688 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.312 0.688 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.312 0.688 0.000
E63.9 Nutritional deficiency, unspecified
0.312 0.688 0.000
E63.8 Other specified nutritional deficiencies
0.312 0.688 0.000
E63.1 Imbalance of constituents of food intake
0.312 0.688 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.312 0.688 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.312 0.688 0.000
E64.8 Sequelae of other nutritional deficiencies
0.312 0.688 0.000
E64.3 Sequelae of rickets
0.312 0.688 0.000
E64.2 Sequelae of vitamin C deficiency
0.312 0.688 0.000
E64.1 Sequelae of vitamin A deficiency
0.312 0.688 0.000
E64.0 Sequelae of protein-energy malnutrition
0.312 0.688 0.000
E53 Deficiency of other B group vitamins
0.311 0.689 0.000
I83 Varicose veins of lower extremities
0.000 0.691 0.309
E51.9 Thiamine deficiency, unspecified
0.302 0.698 0.000
E51.8 Other manifestations of thiamine deficiency
0.302 0.698 0.000
E51.1 Beriberi
0.302 0.698 0.000
E34.5 Androgen resistance syndrome
0.294 0.705 0.001
E34.4 Constitutional tall stature
0.294 0.705 0.001
E34.2 Ectopic hormone secretion, not elsewhere classified
0.294 0.705 0.001
E34.1 Other hypersecretion of intestinal hormones
0.294 0.705 0.001
E56.9 Vitamin deficiency, unspecified
0.292 0.707 0.000
E56.8 Deficiency of other vitamins
0.292 0.707 0.000
E56.0 Deficiency of vitamin E
0.292 0.707 0.000
E61 Deficiency of other nutrient elements
0.289 0.711 0.000
E51.2 Wernicke's encephalopathy
0.289 0.711 0.000
E34.3 Short stature, not elsewhere classified
0.288 0.711 0.001
E34.8 Other specified endocrine disorders
0.283 0.717 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.718 0.282
E56.1 Deficiency of vitamin K
0.266 0.734 0.000
E34.0 Carcinoid syndrome
0.264 0.735 0.001
E04 Other non-toxic goitre
0.262 0.738 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.751 0.249
K75.4 Autoimmune hepatitis
0.240 0.760 0.000
E53.1 Pyridoxine deficiency
0.223 0.777 0.000
E53.0 Riboflavin deficiency
0.223 0.777 0.000
E65-E68 Obesity and other hyperalimentation
0.220 0.779 0.001
E04.0 Non-toxic diffuse goitre
0.218 0.782 0.000
E61.9 Deficiency of nutrient element, unspecified
0.207 0.792 0.000
E61.8 Deficiency of other specified nutrient elements
0.207 0.792 0.000
E61.7 Deficiency of multiple nutrient elements
0.207 0.792 0.000
E61.6 Vanadium deficiency
0.207 0.792 0.000
E61.5 Molybdenum deficiency
0.207 0.792 0.000
E61.4 Chromium deficiency
0.207 0.792 0.000
E61.3 Manganese deficiency
0.207 0.792 0.000
E61.0 Copper deficiency
0.207 0.792 0.000
E53.9 Vitamin B deficiency, unspecified
0.205 0.795 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.796 0.204
K75 Other inflammatory liver diseases
0.199 0.801 0.000
E04.8 Other specified non-toxic goitre
0.188 0.812 0.000
K70-K77 Diseases of liver
0.178 0.822 0.000
K75.8 Other specified inflammatory liver diseases
0.174 0.826 0.000
K74 Fibrosis and cirrhosis of liver
0.168 0.832 0.000
K73 Chronic hepatitis, not elsewhere classified
0.168 0.832 0.000
K74.5 Biliary cirrhosis, unspecified
0.162 0.837 0.000
E61.2 Magnesium deficiency
0.159 0.841 0.000
E67 Other hyperalimentation
0.158 0.841 0.001
E68 Sequelae of hyperalimentation
0.158 0.841 0.001
K72 Hepatic failure, not elsewhere classified
0.157 0.843 0.000
E04.2 Non-toxic multinodular goitre
0.155 0.845 0.000
K73.9 Chronic hepatitis, unspecified
0.152 0.848 0.000
K72.0 Acute and subacute hepatic failure
0.150 0.850 0.000
E34.9 Endocrine disorder, unspecified
0.147 0.852 0.001
E61.1 Iron deficiency
0.147 0.853 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.145 0.855 0.000
K75.2 Nonspecific reactive hepatitis
0.143 0.857 0.000
K75.1 Phlebitis of portal vein
0.143 0.857 0.000
K74.3 Primary biliary cirrhosis
0.141 0.859 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.137 0.862 0.000
E53.8 Deficiency of other specified B group vitamins
0.137 0.863 0.000
K71 Toxic liver disease
0.136 0.864 0.000
K77 Liver disorders in diseases classified elsewhere
0.129 0.871 0.000
K75.0 Abscess of liver
0.122 0.878 0.000
K74.4 Secondary biliary cirrhosis
0.121 0.879 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.121 0.879 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.120 0.879 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.120 0.879 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.120 0.880 0.000
K74.1 Hepatic sclerosis
0.119 0.881 0.000
E67.8 Other specified hyperalimentation
0.113 0.886 0.001
E67.3 Hypervitaminosis D
0.113 0.886 0.001
E67.2 Megavitamin-B6 syndrome
0.113 0.886 0.001
E67.1 Hypercarotenaemia
0.113 0.886 0.001
E67.0 Hypervitaminosis A
0.113 0.886 0.001
K72.1 Chronic hepatic failure
0.113 0.887 0.000
K74.6 Other and unspecified cirrhosis of liver
0.113 0.887 0.000
K71.0 Toxic liver disease with cholestasis
0.108 0.892 0.000
K40 Inguinal hernia
0.000 0.896 0.104
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.102 0.898 0.000
K71.8 Toxic liver disease with other disorders of liver
0.097 0.903 0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.097 0.903 0.000
K71.5 Toxic liver disease with chronic active hepatitis
0.097 0.903 0.000
K71.4 Toxic liver disease with chronic lobular hepatitis
0.097 0.903 0.000
K71.3 Toxic liver disease with chronic persistent hepatitis
0.097 0.903 0.000
K71.2 Toxic liver disease with acute hepatitis
0.097 0.903 0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.096 0.903 0.000
K71.1 Toxic liver disease with hepatic necrosis
0.096 0.903 0.000
K74.0 Hepatic fibrosis
0.096 0.904 0.000
K71.9 Toxic liver disease, unspecified
0.095 0.904 0.000
K77.8 Liver disorders in other diseases classified elsewhere
0.094 0.906 0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.093 0.907 0.000
E14.9 Without complications
0.088 0.912 0.000
K75.9 Inflammatory liver disease, unspecified
0.086 0.914 0.000
M35.0 Sicca syndrome [Sjogren]
0.076 0.924 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.925 0.075
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.925 0.075
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.928 0.072
K72.9 Hepatic failure, unspecified
0.070 0.930 0.000
K76 Other diseases of liver
0.070 0.930 0.000
G20 Parkinson's disease
0.000 0.931 0.069
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.931 0.068
K76.9 Liver disease, unspecified
0.067 0.933 0.000
E07.9 Disorder of thyroid, unspecified
0.066 0.933 0.001
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.935 0.065
E04.1 Non-toxic single thyroid nodule
0.065 0.935 0.000
G20-G26 Extrapyramidal and movement disorders
0.000 0.935 0.065
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.935 0.065
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.937 0.063
T43.2 Other and unspecified antidepressants
0.000 0.937 0.063
G25.8 Other specified extrapyramidal and movement disorders
0.000 0.937 0.063
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.938 0.062
G25 Other extrapyramidal and movement disorders
0.000 0.938 0.062
G24 Dystonia
0.000 0.941 0.059
T39.1 4-Aminophenol derivatives
0.000 0.941 0.059
T46 Poisoning by agents primarily affecting the cardiovascular system
0.000 0.941 0.059
T39.0 Salicylates
0.000 0.943 0.057
T43.6 Psychostimulants with abuse potential
0.000 0.943 0.057
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.943 0.056
T43.5 Other and unspecified antipsychotics and neuroleptics
0.000 0.944 0.056
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.945 0.055
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.000 0.945 0.055
E65 Localised adiposity
0.052 0.945 0.003
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.945 0.054
K90-K93 Other diseases of the digestive system
0.053 0.947 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.947 0.053
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.947 0.053
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.000 0.947 0.053
T43.3 Phenothiazine antipsychotics and neuroleptics
0.000 0.948 0.052
K76.1 Chronic passive congestion of liver
0.052 0.948 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.949 0.051
T50.8 Diagnostic agents
0.000 0.949 0.051
K76.5 Hepatic veno-occlusive disease
0.050 0.950 0.000
K76.4 Peliosis hepatis
0.050 0.950 0.000
K76.3 Infarction of liver
0.050 0.950 0.000
K76.2 Central haemorrhagic necrosis of liver
0.050 0.950 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.950 0.050
G24.8 Other dystonia
0.000 0.950 0.050
G21 Secondary Parkinsonism
0.000 0.950 0.050
E83 Disorders of mineral metabolism
0.004 0.950 0.046
G24.3 Spasmodic torticollis
0.000 0.951 0.049
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.000 0.951 0.049
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.000 0.951 0.049
G25.5 Other chorea
0.000 0.952 0.048
G25.1 Drug-induced tremor
0.000 0.952 0.048
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.952 0.048
T46.1 Calcium-channel blockers
0.000 0.953 0.047
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.953 0.047
T37.8 Other specified systemic anti-infectives and antiparasitics
0.000 0.953 0.047
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.953 0.047
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.953 0.047
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.000 0.953 0.046
G22 Parkinsonism in diseases classified elsewhere
0.000 0.953 0.046
K70 Alcoholic liver disease
0.047 0.953 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.000 0.953 0.046
T43.9 Psychotropic drug, unspecified
0.000 0.954 0.046
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.046 0.954 0.000
T50.4 Drugs affecting uric acid metabolism
0.000 0.954 0.046
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.954 0.046
G24.0 Drug-induced dystonia
0.000 0.954 0.046
T46.5 Other antihypertensive drugs, not elsewhere classified
0.000 0.954 0.045
T39.4 Antirheumatics, not elsewhere classified
0.000 0.954 0.045
T39.2 Pyrazolone derivatives
0.000 0.954 0.045
G23 Other degenerative diseases of basal ganglia
0.000 0.954 0.045
T50.7 Analeptics and opioid receptor antagonists
0.000 0.955 0.045
T50.5 Appetite depressants
0.000 0.955 0.045
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.955 0.045
T50.1 Loop [high-ceiling] diuretics
0.000 0.955 0.045
T50.0 Mineralocorticoids and their antagonists
0.000 0.955 0.045
K76.7 Hepatorenal syndrome
0.045 0.955 0.000
G25.6 Drug-induced tics and other tics of organic origin
0.000 0.955 0.044
G25.4 Drug-induced chorea
0.000 0.955 0.044
G24.9 Dystonia, unspecified
0.000 0.956 0.044
T40.6 Other and unspecified narcotics
0.000 0.956 0.044
T46.3 Coronary vasodilators, not elsewhere classified
0.000 0.956 0.043
G24.5 Blepharospasm
0.000 0.957 0.043
G24.4 Idiopathic orofacial dystonia
0.000 0.957 0.043
G24.2 Idiopathic nonfamilial dystonia
0.000 0.957 0.043
G24.1 Idiopathic familial dystonia
0.000 0.957 0.043
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.000 0.958 0.042
T46.8 Antivaricose drugs, including sclerosing agents
0.000 0.958 0.042
T46.7 Peripheral vasodilators
0.000 0.958 0.042
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.000 0.958 0.042
G25.3 Myoclonus
0.000 0.958 0.042
G25.9 Extrapyramidal and movement disorder, unspecified
0.000 0.958 0.042
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.959 0.041
T42.2 Succinimides and oxazolidinediones
0.000 0.959 0.041
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.000 0.959 0.040
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.960 0.040
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.960 0.040
T40.5 Cocaine
0.000 0.960 0.040
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.961 0.039
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.000 0.961 0.039
T37.5 Antiviral drugs
0.000 0.961 0.039
T37.4 Anthelminthics
0.000 0.961 0.039
T37.3 Other antiprotozoal drugs
0.000 0.961 0.039
T37.2 Antimalarials and drugs acting on other blood protozoa
0.000 0.961 0.039
T37.1 Antimycobacterial drugs
0.000 0.961 0.039
T37.0 Sulphonamides
0.000 0.961 0.039
T48.6 Antiasthmatics, not elsewhere classified
0.000 0.961 0.039
G21.1 Other drug-induced secondary Parkinsonism
0.000 0.961 0.039
K93 Disorders of other digestive organs in diseases classified elsewhere
0.038 0.961 0.000
E11 Non-insulin-dependent diabetes mellitus
0.039 0.961 0.000
T42.3 Barbiturates
0.000 0.961 0.038
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.962 0.038
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.000 0.962 0.038
T40.8 Lysergide [LSD]
0.000 0.962 0.038
T40.7 Cannabis (derivatives)
0.000 0.962 0.038
T40.3 Methadone
0.000 0.962 0.038
T40.0 Opium
0.000 0.962 0.038
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.962 0.038
T40.1 Heroin
0.000 0.962 0.037
T40.4 Other synthetic narcotics
0.000 0.963 0.037
E83.9 Disorder of mineral metabolism, unspecified
0.003 0.963 0.034
N05.9 Unspecified
0.036 0.964 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.000 0.964 0.036
T48.5 Anti-common-cold drugs
0.000 0.964 0.036
T48.4 Expectorants
0.000 0.964 0.036
T48.3 Antitussives
0.000 0.964 0.036
T48.2 Other and unspecified agents primarily acting on muscles
0.000 0.964 0.036
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.000 0.964 0.036
T48.0 Oxytocic drugs
0.000 0.964 0.036
T42.0 Hydantoin derivatives
0.000 0.964 0.036
G21.9 Secondary Parkinsonism, unspecified
0.000 0.964 0.036
G21.8 Other secondary Parkinsonism
0.000 0.964 0.036
G21.3 Postencephalitic Parkinsonism
0.000 0.964 0.036
G21.2 Secondary Parkinsonism due to other external agents
0.000 0.964 0.036
G21.0 Malignant neuroleptic syndrome
0.000 0.964 0.036
G21.4 Vascular parkinsonism
0.000 0.964 0.036
E83.8 Other disorders of mineral metabolism
0.003 0.964 0.033
E83.2 Disorders of zinc metabolism
0.003 0.964 0.033
E83.0 Disorders of copper metabolism
0.003 0.964 0.033
T36 Poisoning by systemic antibiotics
0.000 0.964 0.035
T40.2 Other opioids
0.000 0.964 0.036
G25.0 Essential tremor
0.000 0.965 0.035
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.000 0.965 0.035
K76.6 Portal hypertension
0.035 0.965 0.000
I47.2 Ventricular tachycardia
0.035 0.965 0.000
N05 Unspecified nephritic syndrome
0.035 0.965 0.000
K70.1 Alcoholic hepatitis
0.035 0.965 0.000
T49.9 Topical agent, unspecified
0.000 0.965 0.034
T49.8 Other topical agents
0.000 0.965 0.034
T49.7 Dental drugs, topically applied
0.000 0.965 0.034
T49.6 Otorhinolaryngological drugs and preparations
0.000 0.965 0.034
T49.5 Ophthalmological drugs and preparations
0.000 0.965 0.034
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.000 0.965 0.034
T49.3 Emollients, demulcents and protectants
0.000 0.965 0.034
T49.2 Local astringents and local detergents
0.000 0.965 0.034
T49.1 Antipruritics
0.000 0.965 0.034
T41.5 Therapeutic gases
0.000 0.966 0.034
T41.4 Anaesthetic, unspecified
0.000 0.966 0.034
T41.3 Local anaesthetics
0.000 0.966 0.034
T41.2 Other and unspecified general anaesthetics
0.000 0.966 0.034
T41.1 Intravenous anaesthetics
0.000 0.966 0.034
T41.0 Inhaled anaesthetics
0.000 0.966 0.034
K70.0 Alcoholic fatty liver
0.034 0.966 0.000
T45.0 Antiallergic and antiemetic drugs
0.000 0.966 0.034
G25.2 Other specified forms of tremor
0.000 0.966 0.033
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other
0.033 0.967 0.000
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot
0.033 0.967 0.000
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg
0.033 0.967 0.000
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh
0.033 0.967 0.000
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm
0.033 0.967 0.000
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm
0.033 0.967 0.000
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region
0.033 0.967 0.000
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites
0.033 0.967 0.000
N05.2 Diffuse membranous glomerulonephritis
0.033 0.967 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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