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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3130474
log Bayes Factor = 215.089
Chromosome 6   position 31,199,256  (GRCh37) Explore rs3130474 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D64.9 Anaemia, unspecified
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
M07.3 Other psoriatic arthropathies
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K75 Other inflammatory liver diseases
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
L40-L45 Papulosquamous disorders
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
K90 Intestinal malabsorption
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
D80-D89 Certain disorders involving the immune mechanism
0.999 0.001 0.000
M07 Psoriatic and enteropathic arthropathies
0.999 0.001 0.000
K90-K93 Other diseases of the digestive system
0.999 0.001 0.000
L40.0 Psoriasis vulgaris
0.998 0.002 0.000
M05-M14 Inflammatory polyarthropathies
0.998 0.002 0.000
K75.4 Autoimmune hepatitis
0.998 0.002 0.000
D86 Sarcoidosis
0.998 0.002 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.997 0.003 0.000
E14 Unspecified diabetes mellitus
0.997 0.003 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.997 0.003 0.000
E16 Other disorders of pancreatic internal secretion
0.996 0.004 0.000
D61 Other aplastic anaemias
0.995 0.005 0.000
K72 Hepatic failure, not elsewhere classified
0.994 0.006 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.993 0.007 0.000
M20-M25 Other joint disorders
0.992 0.008 0.000
E16.2 Hypoglycaemia, unspecified
0.990 0.010 0.000
M35.0 Sicca syndrome [Sjogren]
0.990 0.010 0.000
E14.3 With ophthalmic complications
0.990 0.010 0.000
D61.9 Aplastic anaemia, unspecified
0.990 0.010 0.000
M35 Other systemic involvement of connective tissue
0.989 0.011 0.000
Chapter I Certain infectious and parasitic diseases
0.986 0.014 0.000
M45-M49 Spondylopathies
0.981 0.019 0.000
E20-E35 Disorders of other endocrine glands
0.981 0.019 0.000
M45 Ankylosing spondylitis
0.979 0.021 0.000
E11 Non-insulin-dependent diabetes mellitus
0.978 0.022 0.000
K75.8 Other specified inflammatory liver diseases
0.977 0.023 0.000
D86.0 Sarcoidosis of lung
0.968 0.032 0.000
D86.9 Sarcoidosis, unspecified
0.965 0.035 0.000
K72.0 Acute and subacute hepatic failure
0.960 0.040 0.000
K73 Chronic hepatitis, not elsewhere classified
0.960 0.040 0.000
E24 Cushing's syndrome
0.958 0.042 0.000
M34 Systemic sclerosis
0.956 0.044 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.955 0.045 0.000
K72.9 Hepatic failure, unspecified
0.952 0.048 0.000
A15-A19 Tuberculosis
0.947 0.053 0.000
E11.3 With ophthalmic complications
0.946 0.054 0.000
H36.0 Diabetic retinopathy
0.944 0.056 0.000
B15-B19 Viral hepatitis
0.941 0.059 0.000
E10.2 With renal complications
0.938 0.062 0.000
H36 Retinal disorders in diseases classified elsewhere
0.936 0.064 0.000
B35-B49 Mycoses
0.935 0.065 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.934 0.066 0.000
H30-H36 Disorders of choroid and retina
0.930 0.070 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.929 0.070 0.000
Chapter VII Diseases of the eye and adnexa
0.925 0.075 0.000
E10.1 With ketoacidosis
0.924 0.076 0.000
B37 Candidiasis
0.922 0.078 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.922 0.078 0.000
E11.1 With ketoacidosis
0.921 0.079 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.920 0.080 0.000
M33 Dermatopolymyositis
0.917 0.083 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.915 0.085 0.000
L10-L14 Bullous disorders
0.914 0.086 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.911 0.089 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.908 0.092 0.000
L40.1 Generalised pustular psoriasis
0.907 0.093 0.000
K74 Fibrosis and cirrhosis of liver
0.906 0.094 0.000
D80 Immunodeficiency with predominantly antibody defects
0.905 0.095 0.000
B37.0 Candidal stomatitis
0.902 0.098 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.899 0.101 0.000
B18 Chronic viral hepatitis
0.899 0.101 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.894 0.106 0.000
B37.9 Candidiasis, unspecified
0.894 0.106 0.000
K71 Toxic liver disease
0.891 0.109 0.000
L94 Other localised connective tissue disorders
0.883 0.117 0.000
E24.0 Pituitary-dependent Cushing's disease
0.879 0.121 0.000
D86.3 Sarcoidosis of skin
0.879 0.121 0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically
0.877 0.123 0.000
L40.4 Guttate psoriasis
0.871 0.129 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.870 0.130 0.000
D70 Agranulocytosis
0.869 0.131 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.869 0.131 0.000
M33.1 Other dermatomyositis
0.866 0.134 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.866 0.134 0.000
K90.9 Intestinal malabsorption, unspecified
0.863 0.136 0.000
B02 Zoster [herpes zoster]
0.862 0.138 0.000
K73.9 Chronic hepatitis, unspecified
0.861 0.139 0.000
E13 Other specified diabetes mellitus
0.859 0.141 0.000
B18.2 Chronic viral hepatitis C
0.859 0.141 0.000
K74.0 Hepatic fibrosis
0.857 0.143 0.000
K50-K52 Noninfective enteritis and colitis
0.850 0.149 0.001
M34.9 Systemic sclerosis, unspecified
0.851 0.149 0.000
E24.9 Cushing's syndrome, unspecified
0.850 0.150 0.000
E10.7 With multiple complications
0.846 0.154 0.000
E25 Adrenogenital disorders
0.845 0.155 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.843 0.157 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.843 0.157 0.000
K76 Other diseases of liver
0.840 0.160 0.000
L13 Other bullous disorders
0.839 0.161 0.000
K52 Other non-infective gastro-enteritis and colitis
0.839 0.161 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.835 0.165 0.000
D62 Acute posthaemorrhagic anaemia
0.832 0.168 0.000
E03.8 Other specified hypothyroidism
0.831 0.169 0.000
E14.8 With unspecified complications
0.829 0.171 0.000
B02.9 Zoster without complication
0.828 0.172 0.000
L40.8 Other psoriasis
0.825 0.175 0.000
E14.1 With ketoacidosis
0.825 0.175 0.000
A65-A69 Other spirochaetal diseases
0.824 0.176 0.000
L94.0 Localised scleroderma [morphea]
0.823 0.177 0.000
K76.9 Liver disease, unspecified
0.823 0.177 0.000
E24.2 Drug-induced Cushing's syndrome
0.821 0.178 0.000
E10.8 With unspecified complications
0.821 0.179 0.000
E11.2 With renal complications
0.820 0.180 0.000
H46 Optic neuritis
0.818 0.182 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.818 0.182 0.000
M91-M94 Chondropathies
0.815 0.185 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.814 0.186 0.000
N00-N08 Glomerular diseases
0.812 0.188 0.000
E11.6 With other specified complications
0.811 0.189 0.000
D61.1 Drug-induced aplastic anaemia
0.808 0.192 0.000
B17 Other acute viral hepatitis
0.807 0.193 0.000
N04 Nephrotic syndrome
0.807 0.193 0.000
E14.4 With neurological complications
0.806 0.194 0.000
M35.7 Hypermobility syndrome
0.805 0.195 0.000
Chapter XIV Diseases of the genitourinary system
0.805 0.195 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.805 0.195 0.000
M34.1 CR(E)ST syndrome
0.803 0.197 0.000
E27 Other disorders of adrenal gland
0.802 0.198 0.000
H43-H45 Disorders of vitreous body and globe
0.799 0.201 0.000
N04.9 Unspecified
0.796 0.204 0.000
B00 Herpesviral [herpes simplex] infections
0.796 0.204 0.000
D83 Common variable immunodeficiency
0.795 0.205 0.000
M49 Spondylopathies in diseases classified elsewhere
0.794 0.206 0.000
E11.7 With multiple complications
0.794 0.206 0.000
N17-N19 Renal failure
0.792 0.208 0.000
M86-M90 Other osteopathies
0.791 0.209 0.000
L93 Lupus erythematosus
0.790 0.210 0.000
M34.0 Progressive systemic sclerosis
0.789 0.211 0.000
N18 Chronic renal failure
0.787 0.213 0.000
L13.0 Dermatitis herpetiformis
0.786 0.214 0.000
D86.1 Sarcoidosis of lymph nodes
0.786 0.214 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.785 0.215 0.000
A18 Tuberculosis of other organs
0.783 0.217 0.000
M11 Other crystal arthropathies
0.782 0.218 0.000
E23 Hypofunction and other disorders of pituitary gland
0.781 0.219 0.000
E26 Hyperaldosteronism
0.780 0.220 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.777 0.222 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.777 0.223 0.000
N18.9 Chronic renal failure, unspecified
0.777 0.223 0.000
E10.4 With neurological complications
0.776 0.224 0.000
H35 Other retinal disorders
0.772 0.228 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.771 0.229 0.000
E10.6 With other specified complications
0.770 0.229 0.000
A17 Tuberculosis of nervous system
0.770 0.230 0.000
L44 Other papulosquamous disorders
0.770 0.230 0.000
M34.8 Other forms of systemic sclerosis
0.769 0.231 0.000
A20-A28 Certain zoonotic bacterial diseases
0.768 0.232 0.000
M00-M03 Infectious arthropathies
0.767 0.233 0.000
E31 Polyglandular dysfunction
0.767 0.233 0.000
E27.1 Primary adrenocortical insufficiency
0.766 0.234 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.765 0.235 0.000
K75.0 Abscess of liver
0.764 0.236 0.000
L95.8 Other vasculitis limited to skin
0.764 0.236 0.000
L92.0 Granuloma annulare
0.761 0.239 0.000
A80-A89 Viral infections of the central nervous system
0.760 0.240 0.000
A16.9 Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation
0.760 0.240 0.000
E21.3 Hyperparathyroidism, unspecified
0.758 0.242 0.000
M22 Disorders of patella
0.755 0.245 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.755 0.245 0.000
B16 Acute hepatitis B
0.754 0.246 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.754 0.246 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.754 0.246 0.000
B36 Other superficial mycoses
0.753 0.247 0.000
E13.9 Without complications
0.752 0.248 0.000
H30 Chorioretinal inflammation
0.751 0.249 0.000
M08 Juvenile arthritis
0.751 0.249 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.749 0.251 0.000
D55-D59 Haemolytic anaemias
0.749 0.251 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.749 0.251 0.000
K71.0 Toxic liver disease with cholestasis
0.747 0.253 0.000
N05 Unspecified nephritic syndrome
0.747 0.253 0.000
B37.7 Candidal septicaemia
0.743 0.257 0.000
K72.1 Chronic hepatic failure
0.742 0.258 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.741 0.259 0.000
L40.3 Pustulosis palmaris et plantaris
0.740 0.260 0.000
K74.6 Other and unspecified cirrhosis of liver
0.739 0.261 0.000
M07.6 Other enteropathic arthropathies
0.736 0.264 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.735 0.265 0.000
L50-L54 Urticaria and erythema
0.735 0.265 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.734 0.266 0.000
D61.0 Constitutional aplastic anaemia
0.732 0.268 0.000
E10.5 With peripheral circulatory complications
0.731 0.269 0.000
E11.5 With peripheral circulatory complications
0.730 0.270 0.000
L11 Other acantholytic disorders
0.727 0.273 0.000
K71.1 Toxic liver disease with hepatic necrosis
0.727 0.273 0.000
E14.2 Withrenal complications
0.726 0.274 0.000
N05.2 Diffuse membranous glomerulonephritis
0.722 0.278 0.000
H43 Disorders of vitreous body
0.722 0.278 0.000
A16.2 Tuberculosis of lung, without mention of bacteriological or histological confirmation
0.721 0.279 0.000
L94.9 Localised connective tissue disorder, unspecified
0.721 0.279 0.000
H34 Retinal vascular occlusions
0.721 0.279 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.718 0.282 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.718 0.282 0.000
M07.38 Other psoriatic arthropathies (Other)
0.717 0.283 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.717 0.283 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
K77 Liver disorders in diseases classified elsewhere
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
K75.2 Nonspecific reactive hepatitis
0.717 0.283 0.000
K75.1 Phlebitis of portal vein
0.717 0.283 0.000
L41 Parapsoriasis
0.717 0.283 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.717 0.283 0.000
K90.3 Pancreatic steatorrhoea
0.717 0.283 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.717 0.283 0.000
K90.1 Tropical sprue
0.717 0.283 0.000
D81 Combined immunodeficiencies
0.716 0.284 0.000
M07.5 Arthropathy in ulcerative colitis
0.716 0.284 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.716 0.284 0.000
M07.2 Psoriatic spondylitis
0.716 0.284 0.000
M07.1 Arthritis mutilans
0.716 0.284 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.716 0.284 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.716 0.284 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.715 0.284 0.000
E15 Nondiabetic hypoglycaemic coma
0.715 0.285 0.000
E14.7 With multiple complications
0.715 0.285 0.000
E14.0 With coma
0.715 0.285 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.714 0.286 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.714 0.286 0.000
E16.4 Abnormal secretion of gastrin
0.714 0.286 0.000
E16.3 Increased secretion of glucagon
0.714 0.286 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.714 0.286 0.000
D61.8 Other specified aplastic anaemias
0.713 0.286 0.000
D61.3 Idiopathic aplastic anaemia
0.713 0.286 0.000
D61.2 Aplastic anaemia due to other external agents
0.713 0.286 0.000
D73 Diseases of spleen
0.713 0.287 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.712 0.288 0.000
L43 Lichen planus
0.712 0.288 0.000
K35-K38 Diseases of appendix
0.711 0.289 0.000
K76.7 Hepatorenal syndrome
0.709 0.291 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.709 0.291 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.709 0.291 0.000
M35.5 Multifocal fibrosclerosis
0.709 0.291 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.709 0.291 0.000
H35.3 Degeneration of macula and posterior pole
0.709 0.291 0.000
E14.5 With peripheral circulatory complications
0.709 0.291 0.000
B17.1 Acute hepatitis C
0.708 0.292 0.000
B18.1 Chronic viral hepatitis B without delta-agent
0.708 0.292 0.000
A69 Other spirochaetal infections
0.707 0.293 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.707 0.293 0.000
A75-A79 Rickettsioses
0.707 0.293 0.000
A70-A74 Other diseases caused by chlamydiae
0.707 0.293 0.000
E14.9 Without complications
0.707 0.293 0.000
A16.5 Tuberculous pleurisy, without mention of bacteriological or histological confirmation
0.706 0.294 0.000
M13 Other arthritis
0.706 0.294 0.000
D86.8 Sarcoidosis of other and combined sites
0.705 0.295 0.000
D84 Other immunodeficiencies
0.705 0.295 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.704 0.296 0.000
L94.2 Calcinosis cutis
0.704 0.296 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.703 0.297 0.000
E32 Diseases of thymus
0.703 0.297 0.000
E30 Disorders of puberty, not elsewhere classified
0.703 0.297 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.702 0.298 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.702 0.298 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.702 0.298 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.702 0.298 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.702 0.298 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.702 0.298 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.698 0.302 0.000
E10.0 With coma
0.697 0.303 0.000
M60-M63 Disorders of muscles
0.695 0.305 0.000
K75.9 Inflammatory liver disease, unspecified
0.695 0.305 0.000
M93 Other osteochondropathies
0.694 0.306 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.693 0.307 0.000
M22.8 Other disorders of patella
0.693 0.307 0.000
L80 Vitiligo
0.693 0.307 0.000
M21 Other acquired deformities of limbs
0.689 0.311 0.000
M86 Osteomyelitis
0.688 0.312 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.688 0.312 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.688 0.312 0.000
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.687 0.313 0.000
E24.8 Other Cushing's syndrome
0.687 0.313 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.687 0.313 0.000
E24.3 Ectopic ACTH syndrome
0.687 0.313 0.000
E24.1 Nelson's syndrome
0.687 0.313 0.000
K52.3 Indeterminate colitis
0.687 0.313 0.000
B37.3 Candidiasis of vulva and vagina
0.686 0.313 0.000
M24 Other specific joint derangements
0.686 0.314 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.686 0.314 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.686 0.314 0.000
E20 Hypoparathyroidism
0.683 0.316 0.000
N04.2 Diffuse membranous glomerulonephritis
0.683 0.317 0.000
A15 Respiratory tuberculosis, bacteriologically and histologically confirmed
0.681 0.319 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.681 0.319 0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.680 0.320 0.000
A19 Miliary tuberculosis
0.679 0.321 0.000
B01 Varicella [chickenpox]
0.679 0.321 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.678 0.322 0.000
L10 Pemphigus
0.676 0.324 0.000
K90.8 Other intestinal malabsorption
0.676 0.324 0.000
E14.6 With other specified complications
0.674 0.326 0.000
D72 Other disorders of white blood cells
0.674 0.326 0.000
M14 Arthropathies in other diseases classified elsewhere
0.672 0.328 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.671 0.329 0.000
B48 Other mycoses, not elsewhere classified
0.670 0.330 0.000
B47 Mycetoma
0.670 0.330 0.000
B46 Zygomycosis
0.670 0.330 0.000
B45 Cryptococcosis
0.670 0.330 0.000
B43 Chromomycosis and phaeomycotic abscess
0.670 0.330 0.000
B42 Sporotrichosis
0.670 0.330 0.000
B41 Paracoccidioidomycosis
0.670 0.330 0.000
B40 Blastomycosis
0.670 0.330 0.000
B39 Histoplasmosis
0.670 0.330 0.000
B38 Coccidioidomycosis
0.670 0.330 0.000
E06 Thyroiditis
0.667 0.333 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.666 0.333 0.000
A18.1 Tuberculosis of genito-urinary system
0.666 0.334 0.000
E26.0 Primary hyperaldosteronism
0.666 0.334 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.663 0.337 0.000
H43.1 Vitreous haemorrhage
0.662 0.338 0.000
B37.6 Candidal endocarditis
0.661 0.339 0.000
B37.5 Candidal meningitis
0.661 0.339 0.000
B02.1 Zoster meningitis
0.661 0.339 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.661 0.339 0.000
L87 Transepidermal elimination disorders
0.661 0.339 0.000
L86 Keratoderma in diseases classified elsewhere
0.661 0.339 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.661 0.339 0.000
E23.6 Other disorders of pituitary gland
0.660 0.339 0.000
M02 Reactive arthropathies
0.660 0.340 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.659 0.341 0.000
E11.8 With unspecified complications
0.658 0.342 0.000
E16.1 Other hypoglycaemia
0.658 0.342 0.000
M33.9 Dermatopolymyositis, unspecified
0.657 0.343 0.000
M33.0 Juvenile dermatomyositis
0.657 0.343 0.000
D50-D53 Nutritional anaemias
0.657 0.343 0.000
H43.2 Crystalline deposits in vitreous body
0.657 0.343 0.000
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.656 0.344 0.000
H31 Other disorders of choroid
0.656 0.344 0.000
M12 Other specific arthropathies
0.656 0.344 0.000
L14 Bullous disorders in diseases classified elsewhere
0.655 0.345 0.000
E23.7 Disorder of pituitary gland, unspecified
0.655 0.345 0.000
B00.9 Herpesviral infection, unspecified
0.654 0.346 0.000
D64.8 Other specified anaemias
0.654 0.346 0.000
E03.1 Congenital hypothyroidism without goitre
0.654 0.346 0.000
D74 Methaemoglobinaemia
0.653 0.346 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.653 0.346 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.653 0.346 0.000
B25-B34 Other viral diseases
0.651 0.349 0.000
B99-B99 Other infectious diseases
0.651 0.349 0.000
D83.9 Common variable immunodeficiency, unspecified
0.649 0.351 0.000
K74.4 Secondary biliary cirrhosis
0.649 0.351 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.649 0.351 0.000
K74.1 Hepatic sclerosis
0.649 0.351 0.000
D80.8 Other immunodeficiencies with predominantly antibody defects
0.649 0.351 0.000
D80.7 Transient hypogammaglobulinaemia of infancy
0.649 0.351 0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.649 0.351 0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.649 0.351 0.000
D80.0 Hereditary hypogammaglobulinaemia
0.649 0.351 0.000
H35.2 Other proliferative retinopathy
0.647 0.353 0.000
N17 Acute renal failure
0.647 0.353 0.000
B00.1 Herpesviral vesicular dermatitis
0.646 0.354 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.646 0.354 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.646 0.354 0.000
B06 Rubella [German measles]
0.645 0.355 0.000
B05 Measles
0.645 0.355 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.645 0.355 0.000
B04 Monkeypox
0.645 0.355 0.000
B03 Smallpox
0.645 0.355 0.000
L42 Pityriasis rosea
0.645 0.355 0.000
B18.8 Other chronic viral hepatitis
0.644 0.356 0.000
B18.0 Chronic viral hepatitis B with delta-agent
0.644 0.356 0.000
L84 Corns and callosities
0.644 0.356 0.000
A17.0 Tuberculous meningitis
0.644 0.356 0.000
L93.0 Discoid lupus erythematosus
0.641 0.358 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.641 0.359 0.000
H34.8 Other retinal vascular occlusions
0.641 0.359 0.000
D82 Immunodeficiency associated with other major defects
0.640 0.359 0.000
B18.9 Chronic viral hepatitis, unspecified
0.640 0.359 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.640 0.360 0.000
M32 Systemic lupus erythematosus
0.639 0.361 0.000
K71.9 Toxic liver disease, unspecified
0.639 0.361 0.000
K71.8 Toxic liver disease with other disorders of liver
0.639 0.361 0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.639 0.361 0.000
K71.5 Toxic liver disease with chronic active hepatitis
0.639 0.361 0.000
K71.4 Toxic liver disease with chronic lobular hepatitis
0.639 0.361 0.000
K71.3 Toxic liver disease with chronic persistent hepatitis
0.639 0.361 0.000
K71.2 Toxic liver disease with acute hepatitis
0.639 0.361 0.000
A87 Viral meningitis
0.639 0.361 0.000
N18.0 End-stage renal disease
0.638 0.362 0.000
M33.2 Polymyositis
0.638 0.362 0.000
B65-B83 Helminthiases
0.638 0.362 0.000
B02.8 Zoster with other complications
0.636 0.364 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.635 0.365 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.633 0.367 0.000
L94.6 Ainhum
0.633 0.367 0.000
L94.5 Poikiloderma vasculare atrophicans
0.633 0.367 0.000
L94.4 Gottron's papules
0.633 0.367 0.000
L94.3 Sclerodactyly
0.633 0.367 0.000
L94.1 Linear scleroderma
0.633 0.367 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.633 0.367 0.000
E13.3 With ophthalmic complications
0.632 0.368 0.000
E21.2 Other hyperparathyroidism
0.631 0.369 0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.631 0.369 0.000
L56 Other acute skin changes due to ultraviolet radiation
0.630 0.370 0.000
L94.8 Other specified localised connective tissue disorders
0.630 0.370 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.630 0.370 0.000
L93.1 Subacute cutaneous lupus erythematosus
0.629 0.371 0.000
K36 Other appendicitis
0.629 0.371 0.000
A16.8 Other respiratory tuberculosis, without mention of bacteriological or histological confirmation
0.629 0.371 0.000
A16.7 Primary respiratory tuberculosis without mention of bacteriological or histological confirmation
0.629 0.371 0.000
A16.4 Tuberculosis of larynx, trachea and bronchus, without mention of bacteriological or histological confirmation
0.629 0.371 0.000
A16.3 Tuberculosis of intrathoracic lymph nodes, without mention of bacteriological or histological confirmation
0.629 0.371 0.000
A16.1 Tuberculosis of lung, bacteriological and histological examination not done
0.629 0.371 0.000
A16.0 Tuberculosis of lung, bacteriologically and histologically negative
0.629 0.371 0.000
M13.0 Polyarthritis, unspecified
0.628 0.372 0.000
H30.9 Chorioretinal inflammation, unspecified
0.626 0.374 0.000
A69.2 Lyme disease
0.624 0.376 0.000
N04.1 Focal and segmental glomerular lesions
0.624 0.376 0.000
M22.2 Patellofemoral disorders
0.624 0.376 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.623 0.376 0.000
M11.2 Other chondrocalcinosis
0.623 0.377 0.000
E29 Testicular dysfunction
0.623 0.377 0.000
L88 Pyoderma gangrenosum
0.622 0.377 0.000
B36.9 Superficial mycosis, unspecified
0.622 0.378 0.000
N18.1 Chronic kidney disease, stage 1
0.622 0.378 0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma
0.621 0.379 0.000
H35.5 Hereditary retinal dystrophy
0.620 0.380 0.000
M88 Paget's disease of bone [osteitis deformans]
0.619 0.381 0.000
L52 Erythema nodosum
0.618 0.382 0.000
N18.4 Chronic kidney disease, stage 4
0.618 0.382 0.000
B02.7 Disseminated zoster
0.618 0.382 0.000
B02.0 Zoster encephalitis
0.618 0.382 0.000
B37.2 Candidiasis of skin and nail
0.617 0.383 0.000
E13.8 With unspecified complications
0.616 0.384 0.000
E13.7 With multiple complications
0.616 0.384 0.000
E13.6 With other specified complications
0.616 0.384 0.000
E13.5 With peripheral circulatory complications
0.616 0.384 0.000
E13.4 With neurological complications
0.616 0.384 0.000
E13.2 With renal complications
0.616 0.384 0.000
E13.1 With ketoacidosis
0.616 0.384 0.000
E13.0 With coma
0.616 0.384 0.000
N25-N29 Other disorders of kidney and ureter
0.616 0.384 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.615 0.385 0.000
B50-B64 Protozoal diseases
0.614 0.386 0.000
B02.3 Zoster ocular disease
0.614 0.386 0.000
E31.0 Autoimmune polyglandular failure
0.613 0.387 0.000
M93.9 Osteochondropathy, unspecified
0.612 0.388 0.000
D59 Acquired haemolytic anaemia
0.612 0.388 0.000
B00.5 Herpesviral ocular disease
0.610 0.390 0.000
H35.8 Other specified retinal disorders
0.609 0.391 0.000
B37.4 Candidiasis of other urogenital sites
0.608 0.392 0.000
E40-E46 Malnutrition
0.607 0.393 0.000
E25.9 Adrenogenital disorder, unspecified
0.606 0.394 0.000
E25.8 Other adrenogenital disorders
0.606 0.394 0.000
N18.2 Chronic kidney disease, stage 2
0.606 0.394 0.000
B02.2 Zoster with other nervous system involvement
0.606 0.394 0.000
L44.0 Pityriasis rubra pilaris
0.606 0.394 0.000
M46 Other inflammatory spondylopathies
0.604 0.396 0.000
E27.9 Disorder of adrenal gland, unspecified
0.603 0.397 0.000
K76.5 Hepatic veno-occlusive disease
0.602 0.398 0.000
K76.4 Peliosis hepatis
0.602 0.398 0.000
K76.3 Infarction of liver
0.602 0.398 0.000
K76.2 Central haemorrhagic necrosis of liver
0.602 0.398 0.000
L13.9 Bullous disorder, unspecified
0.602 0.398 0.000
L13.8 Other specified bullous disorders
0.602 0.398 0.000
L13.1 Subcorneal pustular dermatitis
0.602 0.398 0.000
B44 Aspergillosis
0.600 0.400 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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