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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3131290
log Bayes Factor = 209.909
Chromosome 6   position 32,183,175  (GRCh37) Explore rs3131290 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E11.9 Without complications
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.999 0.001 0.000
E16 Other disorders of pancreatic internal secretion
0.999 0.001 0.000
G35 Multiple sclerosis
0.000 0.001 0.999
E16.2 Hypoglycaemia, unspecified
0.998 0.002 0.000
E10.1 With ketoacidosis
0.997 0.003 0.000
E14 Unspecified diabetes mellitus
0.994 0.006 0.000
E14.3 With ophthalmic complications
0.989 0.011 0.000
E20-E35 Disorders of other endocrine glands
0.984 0.016 0.000
E27 Other disorders of adrenal gland
0.975 0.025 0.000
E27.1 Primary adrenocortical insufficiency
0.962 0.038 0.000
E10.2 With renal complications
0.955 0.045 0.000
E13 Other specified diabetes mellitus
0.937 0.063 0.000
E11.3 With ophthalmic complications
0.932 0.068 0.000
E10.4 With neurological complications
0.914 0.086 0.000
E13.9 Without complications
0.895 0.105 0.000
E11.5 With peripheral circulatory complications
0.882 0.118 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.876 0.124 0.000
E11.1 With ketoacidosis
0.860 0.140 0.000
E10.0 With coma
0.855 0.145 0.000
E10.6 With other specified complications
0.855 0.145 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.849 0.151 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.842 0.158 0.000
E16.1 Other hypoglycaemia
0.838 0.162 0.000
K90 Intestinal malabsorption
0.821 0.179 0.000
E14.5 With peripheral circulatory complications
0.806 0.194 0.000
E10.7 With multiple complications
0.805 0.195 0.000
N05 Unspecified nephritic syndrome
0.804 0.196 0.000
E14.8 With unspecified complications
0.804 0.196 0.000
E11.0 With coma
0.804 0.196 0.000
N00-N08 Glomerular diseases
0.803 0.197 0.000
N04 Nephrotic syndrome
0.794 0.206 0.000
E05.8 Other thyrotoxicosis
0.794 0.206 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.213 0.787
E24 Cushing's syndrome
0.787 0.213 0.000
K90.9 Intestinal malabsorption, unspecified
0.781 0.219 0.000
E06 Thyroiditis
0.777 0.223 0.000
N04.9 Unspecified
0.775 0.225 0.000
N05.9 Unspecified
0.772 0.228 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.771 0.229 0.000
N05.2 Diffuse membranous glomerulonephritis
0.771 0.229 0.000
E10.5 With peripheral circulatory complications
0.769 0.231 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.765 0.235 0.000
E65-E68 Obesity and other hyperalimentation
0.765 0.235 0.000
E50-E64 Other nutritional deficiencies
0.760 0.240 0.000
E29 Testicular dysfunction
0.757 0.243 0.000
E23 Hypofunction and other disorders of pituitary gland
0.756 0.244 0.000
E10.8 With unspecified complications
0.753 0.247 0.000
E40-E46 Malnutrition
0.750 0.250 0.000
E14.2 Withrenal complications
0.750 0.250 0.000
E31 Polyglandular dysfunction
0.750 0.250 0.000
E14.1 With ketoacidosis
0.749 0.251 0.000
G37 Other demyelinating diseases of central nervous system
0.000 0.255 0.744
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.733 0.266 0.000
E03.8 Other specified hypothyroidism
0.725 0.275 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.280 0.720
E20 Hypoparathyroidism
0.719 0.281 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.716 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.716 0.284 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.716 0.284 0.000
E16.4 Abnormal secretion of gastrin
0.716 0.284 0.000
E16.3 Increased secretion of glucagon
0.716 0.284 0.000
E14.7 With multiple complications
0.712 0.288 0.000
E14.0 With coma
0.712 0.288 0.000
E11.2 With renal complications
0.708 0.292 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.707 0.293 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.706 0.294 0.000
E32 Diseases of thymus
0.706 0.294 0.000
E30 Disorders of puberty, not elsewhere classified
0.706 0.294 0.000
E14.4 With neurological complications
0.702 0.298 0.000
E27.5 Adrenomedullary hyperfunction
0.699 0.301 0.000
E27.0 Other adrenocortical overactivity
0.699 0.301 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.693 0.307 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.690 0.310 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.689 0.311 0.000
E28 Ovarian dysfunction
0.688 0.312 0.000
E65 Localised adiposity
0.688 0.312 0.000
N04.2 Diffuse membranous glomerulonephritis
0.686 0.314 0.000
E53 Deficiency of other B group vitamins
0.684 0.316 0.000
E25 Adrenogenital disorders
0.684 0.316 0.000
J45.9 Asthma, unspecified
0.683 0.317 0.000
N03 Chronic nephritic syndrome
0.678 0.322 0.000
E24.2 Drug-induced Cushing's syndrome
0.675 0.325 0.000
E13.8 With unspecified complications
0.671 0.328 0.000
E13.7 With multiple complications
0.671 0.328 0.000
E13.6 With other specified complications
0.671 0.328 0.000
E13.5 With peripheral circulatory complications
0.671 0.328 0.000
E13.4 With neurological complications
0.671 0.328 0.000
E13.2 With renal complications
0.671 0.328 0.000
E13.1 With ketoacidosis
0.671 0.328 0.000
E13.0 With coma
0.671 0.328 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.663 0.337 0.000
E11.6 With other specified complications
0.662 0.338 0.000
E27.2 Addisonian crisis
0.657 0.343 0.000
E53.8 Deficiency of other specified B group vitamins
0.655 0.345 0.000
E14.6 With other specified complications
0.653 0.347 0.000
E13.3 With ophthalmic complications
0.651 0.349 0.000
E03.1 Congenital hypothyroidism without goitre
0.646 0.353 0.000
K90.8 Other intestinal malabsorption
0.642 0.358 0.000
E26 Hyperaldosteronism
0.637 0.363 0.000
N04.1 Focal and segmental glomerular lesions
0.635 0.365 0.000
E22 Hyperfunction of pituitary gland
0.633 0.367 0.000
E23.2 Diabetes insipidus
0.629 0.371 0.000
N03.1 Focal and segmental glomerular lesions
0.625 0.375 0.000
N05.1 Focal and segmental glomerular lesions
0.623 0.377 0.000
E23.7 Disorder of pituitary gland, unspecified
0.619 0.380 0.000
E21.3 Hyperparathyroidism, unspecified
0.607 0.393 0.000
N02 Recurrent and persistent haematuria
0.604 0.396 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.600 0.400 0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.594 0.405 0.000
E29.1 Testicular hypofunction
0.593 0.407 0.000
E06.5 Other chronic thyroiditis
0.593 0.407 0.000
E27.9 Disorder of adrenal gland, unspecified
0.592 0.408 0.000
K90.3 Pancreatic steatorrhoea
0.588 0.411 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.588 0.411 0.000
K90.1 Tropical sprue
0.588 0.411 0.000
E23.6 Other disorders of pituitary gland
0.586 0.414 0.000
E06.3 Autoimmune thyroiditis
0.586 0.414 0.000
E11.8 With unspecified complications
0.583 0.417 0.000
E31.0 Autoimmune polyglandular failure
0.582 0.418 0.000
E51 Thiamine deficiency
0.581 0.418 0.000
N05.6 Dense deposit disease
0.577 0.423 0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.577 0.423 0.000
N05.0 Minor glomerular abnormality
0.577 0.423 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.575 0.424 0.000
N06 Isolated proteinuria with specified morphological lesion
0.575 0.424 0.000
N01 Rapidly progressive nephritic syndrome
0.575 0.424 0.000
E27.8 Other specified disorders of adrenal gland
0.573 0.427 0.000
N02.2 Diffuse membranous glomerulonephritis
0.573 0.427 0.000
E46 Unspecified protein-energy malnutrition
0.571 0.429 0.000
N04.8 Other
0.570 0.430 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.570 0.430 0.000
N04.6 Dense deposit disease
0.570 0.430 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.570 0.430 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.570 0.430 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.570 0.430 0.000
N04.0 Minor glomerular abnormality
0.570 0.430 0.000
E24.0 Pituitary-dependent Cushing's disease
0.568 0.432 0.000
G36 Other acute disseminated demyelination
0.000 0.435 0.564
E24.8 Other Cushing's syndrome
0.564 0.436 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.564 0.436 0.000
E24.3 Ectopic ACTH syndrome
0.564 0.436 0.000
E24.1 Nelson's syndrome
0.564 0.436 0.000
N00 Acute nephritic syndrome
0.562 0.438 0.000
E06.1 Subacute thyroiditis
0.559 0.441 0.000
E06.4 Drug-induced thyroiditis
0.557 0.443 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.557 0.443 0.000
E06.0 Acute thyroiditis
0.557 0.443 0.000
E06.9 Thyroiditis, unspecified
0.557 0.443 0.000
E22.1 Hyperprolactinaemia
0.554 0.446 0.000
E28.3 Primary ovarian failure
0.551 0.449 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.549 0.451 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.549 0.451 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.549 0.451 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.549 0.451 0.000
E67 Other hyperalimentation
0.549 0.451 0.000
E68 Sequelae of hyperalimentation
0.549 0.451 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.545 0.455 0.000
E63 Other nutritional deficiencies
0.545 0.455 0.000
E50 Vitamin A deficiency
0.545 0.455 0.000
E60 Dietary zinc deficiency
0.545 0.455 0.000
E59 Dietary selenium deficiency
0.545 0.455 0.000
E54 Ascorbic acid deficiency
0.545 0.455 0.000
E52 Niacin deficiency [pellagra]
0.545 0.455 0.000
N05.7 Diffuse crescentic glomerulonephritis
0.544 0.456 0.000
E29.9 Testicular dysfunction, unspecified
0.542 0.457 0.000
E29.8 Other testicular dysfunction
0.542 0.457 0.000
E29.0 Testicular hyperfunction
0.542 0.457 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.542 0.458 0.000
E23.1 Drug-induced hypopituitarism
0.542 0.458 0.000
E34 Other endocrine disorders
0.542 0.458 0.000
E58 Dietary calcium deficiency
0.541 0.459 0.000
N03.8 Other
0.540 0.460 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.538 0.462 0.000
E45 Retarded development following protein-energy malnutrition
0.538 0.462 0.000
E43 Unspecified severe protein-energy malnutrition
0.538 0.462 0.000
E42 Marasmic kwashiorkor
0.538 0.462 0.000
E41 Nutritional marasmus
0.538 0.462 0.000
E40 Kwashiorkor
0.538 0.462 0.000
E31.9 Polyglandular dysfunction, unspecified
0.538 0.462 0.000
E31.8 Other polyglandular dysfunction
0.538 0.462 0.000
E31.1 Polyglandular hyperfunction
0.538 0.462 0.000
G37.5 Concentric sclerosis [Balo]
0.000 0.466 0.534
G37.4 Subacute necrotising myelitis
0.000 0.466 0.534
G37.2 Central pontine myelinolysis
0.000 0.466 0.534
G37.1 Central demyelination of corpus callosum
0.000 0.466 0.534
G37.0 Diffuse sclerosis
0.000 0.466 0.534
E20.9 Hypoparathyroidism, unspecified
0.529 0.471 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.528 0.472 0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis
0.527 0.473 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.524 0.476 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.481 0.519
E07 Other disorders of thyroid
0.519 0.481 0.000
E20.8 Other hypoparathyroidism
0.515 0.484 0.000
E20.1 Pseudohypoparathyroidism
0.515 0.484 0.000
E20.0 Idiopathic hypoparathyroidism
0.515 0.484 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E21.4 Other specified disorders of parathyroid gland
0.513 0.487 0.000
E56 Other vitamin deficiencies
0.510 0.490 0.000
N05.8 Other
0.506 0.493 0.000
E30.9 Disorder of puberty, unspecified
0.506 0.494 0.000
E30.8 Other disorders of puberty
0.506 0.494 0.000
E30.1 Precocious puberty
0.506 0.494 0.000
E30.0 Delayed puberty
0.506 0.494 0.000
E32.9 Disease of thymus, unspecified
0.506 0.494 0.000
E32.8 Other diseases of thymus
0.506 0.494 0.000
E32.1 Abscess of thymus
0.506 0.494 0.000
E32.0 Persistent hyperplasia of thymus
0.506 0.494 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.506 0.494 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.506 0.494 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.506 0.494 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.503 0.496 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.497 0.503
E24.9 Cushing's syndrome, unspecified
0.500 0.500 0.000
E28.9 Ovarian dysfunction, unspecified
0.493 0.506 0.000
E28.8 Other ovarian dysfunction
0.493 0.506 0.000
E28.1 Androgen excess
0.493 0.506 0.000
E28.0 Oestrogen excess
0.493 0.506 0.000
E53.1 Pyridoxine deficiency
0.491 0.509 0.000
E53.0 Riboflavin deficiency
0.491 0.509 0.000
E25.9 Adrenogenital disorder, unspecified
0.490 0.509 0.000
E25.8 Other adrenogenital disorders
0.490 0.509 0.000
N03.7 Diffuse crescentic glomerulonephritis
0.486 0.514 0.000
N03.6 Dense deposit disease
0.486 0.514 0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis
0.486 0.514 0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis
0.486 0.514 0.000
N03.2 Diffuse membranous glomerulonephritis
0.486 0.514 0.000
N03.0 Minor glomerular abnormality
0.486 0.514 0.000
E83.1 Disorders of iron metabolism
0.000 0.527 0.473
E61 Deficiency of other nutrient elements
0.472 0.528 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.469 0.531 0.000
N02.3 Diffuse mesangial proliferative glomerulonephritis
0.468 0.532 0.000
E21.2 Other hyperparathyroidism
0.463 0.537 0.000
E26.8 Other hyperaldosteronism
0.457 0.543 0.000
E26.1 Secondary hyperaldosteronism
0.457 0.543 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.454 0.546 0.000
E22.8 Other hyperfunction of pituitary gland
0.454 0.546 0.000
E51.2 Wernicke's encephalopathy
0.453 0.547 0.000
E26.9 Hyperaldosteronism, unspecified
0.445 0.555 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.444 0.556 0.000
N02.7 Diffuse crescentic glomerulonephritis
0.433 0.567 0.000
N02.6 Dense deposit disease
0.433 0.567 0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis
0.433 0.567 0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis
0.433 0.567 0.000
N02.1 Focal and segmental glomerular lesions
0.433 0.567 0.000
H36.0 Diabetic retinopathy
0.425 0.575 0.000
E51.9 Thiamine deficiency, unspecified
0.417 0.583 0.000
E51.8 Other manifestations of thiamine deficiency
0.417 0.583 0.000
E51.1 Beriberi
0.417 0.583 0.000
E34.8 Other specified endocrine disorders
0.416 0.583 0.000
N01.9 Unspecified
0.413 0.587 0.000
N01.8 Other
0.413 0.587 0.000
N01.7 Diffuse crescentic glomerulonephritis
0.413 0.587 0.000
N01.6 Dense deposit disease
0.413 0.587 0.000
N01.5 Diffuse mesangiocapillary glomerulonephritis
0.413 0.587 0.000
N01.4 Diffuse endocapillary proliferative glomerulonephritis
0.413 0.587 0.000
N01.3 Diffuse mesangial proliferative glomerulonephritis
0.413 0.587 0.000
N01.2 Diffuse membranous glomerulonephritis
0.413 0.587 0.000
N01.1 Focal and segmental glomerular lesions
0.413 0.587 0.000
N01.0 Minor glomerular abnormality
0.413 0.587 0.000
N06.9 Unspecified
0.413 0.587 0.000
N06.8 Other
0.413 0.587 0.000
N06.7 Diffuse crescentic glomerulonephritis
0.413 0.587 0.000
N06.6 Dense deposit disease
0.413 0.587 0.000
N06.5 Diffuse mesangiocapillary glomerulonephritis
0.413 0.587 0.000
N06.4 Diffuse endocapillary proliferative glomerulonephritis
0.413 0.587 0.000
N06.3 Diffuse mesangial proliferative glomerulonephritis
0.413 0.587 0.000
N06.2 Diffuse membranous glomerulonephritis
0.413 0.587 0.000
N06.1 Focal and segmental glomerular lesions
0.413 0.587 0.000
N06.0 Minor glomerular abnormality
0.413 0.587 0.000
N07.9 Unspecified
0.413 0.587 0.000
N07.8 Other
0.413 0.587 0.000
N07.7 Diffuse crescentic glomerulonephritis
0.413 0.587 0.000
N07.6 Dense deposit disease
0.413 0.587 0.000
N07.5 Diffuse mesangiocapillary glomerulonephritis
0.413 0.587 0.000
N07.4 Diffuse endocapillary proliferative glomerulonephritis
0.413 0.587 0.000
N07.3 Diffuse mesangial proliferative glomerulonephritis
0.413 0.587 0.000
N07.2 Diffuse membranous glomerulonephritis
0.413 0.587 0.000
N07.1 Focal and segmental glomerular lesions
0.413 0.587 0.000
N07.0 Minor glomerular abnormality
0.413 0.587 0.000
G36.9 Acute disseminated demyelination, unspecified
0.000 0.595 0.405
G36.8 Other specified acute disseminated demyelination
0.000 0.595 0.405
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.595 0.405
G36.0 Neuromyelitis optica [Devic]
0.000 0.595 0.405
E26.0 Primary hyperaldosteronism
0.404 0.596 0.000
N00.8 Other
0.403 0.597 0.000
N00.7 Diffuse crescentic glomerulonephritis
0.403 0.597 0.000
N00.6 Dense deposit disease
0.403 0.597 0.000
N00.5 Diffuse mesangiocapillary glomerulonephritis
0.403 0.597 0.000
N00.4 Diffuse endocapillary proliferative glomerulonephritis
0.403 0.597 0.000
N00.3 Diffuse mesangial proliferative glomerulonephritis
0.403 0.597 0.000
N00.2 Diffuse membranous glomerulonephritis
0.403 0.597 0.000
N00.1 Focal and segmental glomerular lesions
0.403 0.597 0.000
N00.0 Minor glomerular abnormality
0.403 0.597 0.000
N02.0 Minor glomerular abnormality
0.402 0.598 0.000
E67.8 Other specified hyperalimentation
0.393 0.606 0.000
E67.3 Hypervitaminosis D
0.393 0.606 0.000
E67.2 Megavitamin-B6 syndrome
0.393 0.606 0.000
E67.1 Hypercarotenaemia
0.393 0.606 0.000
E67.0 Hypervitaminosis A
0.393 0.606 0.000
E55 Vitamin D deficiency
0.391 0.609 0.000
E50.9 Vitamin A deficiency, unspecified
0.391 0.609 0.000
E50.8 Other manifestations of vitamin A deficiency
0.391 0.609 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.391 0.609 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.391 0.609 0.000
E50.5 Vitamin A deficiency with night blindness
0.391 0.609 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.391 0.609 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.391 0.609 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.391 0.609 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.391 0.609 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.391 0.609 0.000
E63.9 Nutritional deficiency, unspecified
0.391 0.609 0.000
E63.8 Other specified nutritional deficiencies
0.391 0.609 0.000
E63.1 Imbalance of constituents of food intake
0.391 0.609 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.391 0.609 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.391 0.609 0.000
E64.8 Sequelae of other nutritional deficiencies
0.391 0.609 0.000
E64.3 Sequelae of rickets
0.391 0.609 0.000
E64.2 Sequelae of vitamin C deficiency
0.391 0.609 0.000
E64.1 Sequelae of vitamin A deficiency
0.391 0.609 0.000
E64.0 Sequelae of protein-energy malnutrition
0.391 0.609 0.000
N00.9 Unspecified
0.390 0.610 0.000
E34.5 Androgen resistance syndrome
0.388 0.611 0.000
E34.4 Constitutional tall stature
0.388 0.611 0.000
E34.3 Short stature, not elsewhere classified
0.388 0.611 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.388 0.611 0.000
E34.1 Other hypersecretion of intestinal hormones
0.388 0.611 0.000
E28.2 Polycystic ovarian syndrome
0.388 0.612 0.000
E44.1 Mild protein-energy malnutrition
0.386 0.614 0.000
E44.0 Moderate protein-energy malnutrition
0.386 0.614 0.000
E07.1 Dyshormogenetic goitre
0.372 0.628 0.000
E07.0 Hypersecretion of calcitonin
0.372 0.628 0.000
E56.9 Vitamin deficiency, unspecified
0.366 0.634 0.000
E56.8 Deficiency of other vitamins
0.366 0.634 0.000
E56.0 Deficiency of vitamin E
0.366 0.634 0.000
E61.2 Magnesium deficiency
0.363 0.637 0.000
E07.8 Other specified disorders of thyroid
0.356 0.643 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.350 0.650 0.000
E14.9 Without complications
0.349 0.651 0.000
E61.9 Deficiency of nutrient element, unspecified
0.339 0.661 0.000
E61.8 Deficiency of other specified nutrient elements
0.339 0.661 0.000
E61.7 Deficiency of multiple nutrient elements
0.339 0.661 0.000
E61.6 Vanadium deficiency
0.339 0.661 0.000
E61.5 Molybdenum deficiency
0.339 0.661 0.000
E61.4 Chromium deficiency
0.339 0.661 0.000
E61.3 Manganese deficiency
0.339 0.661 0.000
E61.0 Copper deficiency
0.339 0.661 0.000
E53.9 Vitamin B deficiency, unspecified
0.331 0.669 0.001
E56.1 Deficiency of vitamin K
0.331 0.669 0.000
E34.0 Carcinoid syndrome
0.330 0.669 0.000
E66 Obesity
0.293 0.707 0.000
E55.0 Rickets, active
0.281 0.719 0.000
E22.0 Acromegaly and pituitary gigantism
0.272 0.727 0.000
E34.9 Endocrine disorder, unspecified
0.260 0.740 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.252 0.748 0.000
E11.4 With neurological complications
0.250 0.750 0.000
N02.8 Other
0.248 0.752 0.000
E21.0 Primary hyperparathyroidism
0.231 0.769 0.000
H36 Retinal disorders in diseases classified elsewhere
0.225 0.775 0.000
E61.1 Iron deficiency
0.219 0.781 0.000
N02.9 Unspecified
0.211 0.789 0.000
E66.1 Drug-induced obesity
0.210 0.790 0.000
E23.0 Hypopituitarism
0.209 0.791 0.000
E07.9 Disorder of thyroid, unspecified
0.206 0.794 0.000
D64.9 Anaemia, unspecified
0.177 0.823 0.000
E66.0 Obesity due to excess calories
0.173 0.827 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.161 0.838 0.000
E66.8 Other obesity
0.159 0.841 0.000
M20.1 Hallux valgus (acquired)
0.000 0.849 0.151
E83 Disorders of mineral metabolism
0.016 0.858 0.126
J45 Asthma
0.140 0.860 0.000
Y42.7 Androgens and anabolic congeners
0.139 0.861 0.000
E55.9 Vitamin D deficiency, unspecified
0.127 0.873 0.000
E83.3 Disorders of phosphorus metabolism
0.003 0.878 0.119
D64 Other anaemias
0.117 0.883 0.000
J45.1 Nonallergic asthma
0.108 0.892 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.011 0.897 0.092
E83.8 Other disorders of mineral metabolism
0.012 0.898 0.091
E83.2 Disorders of zinc metabolism
0.012 0.898 0.091
E83.0 Disorders of copper metabolism
0.012 0.898 0.091
N03.9 Unspecified
0.097 0.903 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.095 0.905 0.000
E89.0 Postprocedural hypothyroidism
0.094 0.906 0.000
E04 Other non-toxic goitre
0.093 0.907 0.000
C83.3 Large cell (diffuse)
0.093 0.907 0.000
E70-E90 Metabolic disorders
0.092 0.908 0.001
D64.3 Other sideroblastic anaemias
0.086 0.914 0.000
J45.8 Mixed asthma
0.086 0.914 0.000
D64.4 Congenital dyserythropoietic anaemia
0.084 0.916 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.084 0.916 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.084 0.916 0.000
D64.0 Hereditary sideroblastic anaemia
0.084 0.916 0.000
H30-H36 Disorders of choroid and retina
0.082 0.918 0.000
D64.8 Other specified anaemias
0.081 0.919 0.000
E89.2 Postprocedural hypoparathyroidism
0.080 0.920 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.076 0.924 0.000
D60-D64 Aplastic and other anaemias
0.075 0.925 0.000
H34 Retinal vascular occlusions
0.074 0.926 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.074 0.926 0.000
E89.3 Postprocedural hypopituitarism
0.073 0.927 0.000
E70 Disorders of aromatic amino-acid metabolism
0.072 0.927 0.000
E89.5 Postprocedural testicular hypofunction
0.072 0.928 0.000
H31 Other disorders of choroid
0.071 0.929 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.071 0.929 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.068 0.932 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.068 0.932 0.000
E89.1 Postprocedural hypoinsulinaemia
0.068 0.932 0.000
H34.8 Other retinal vascular occlusions
0.068 0.932 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.068 0.932 0.000
E04.8 Other specified non-toxic goitre
0.067 0.933 0.000
E89.4 Postprocedural ovarian failure
0.067 0.933 0.000
E04.0 Non-toxic diffuse goitre
0.066 0.933 0.000
D80-D89 Certain disorders involving the immune mechanism
0.066 0.934 0.000
E77 Disorders of glycoprotein metabolism
0.066 0.934 0.001
E76 Disorders of glycosaminoglycan metabolism
0.066 0.934 0.001
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.066 0.934 0.001
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.066 0.934 0.001
E72 Other disorders of amino-acid metabolism
0.065 0.934 0.001
H31.0 Chorioretinal scars
0.065 0.935 0.000
C83.7 Burkitt's tumour
0.065 0.935 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.063 0.937 0.000
E84 Cystic fibrosis
0.063 0.937 0.001
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.062 0.937 0.001
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.063 0.937 0.000
E79 Disorders of purine and pyrimidine metabolism
0.062 0.938 0.001
D80 Immunodeficiency with predominantly antibody defects
0.062 0.938 0.000
C83.1 Small cleaved cell (diffuse)
0.062 0.938 0.000
H30 Chorioretinal inflammation
0.062 0.938 0.000
C83.0 Small cell (diffuse)
0.060 0.940 0.000
Y42.2 Antithyroid drugs
0.060 0.940 0.000
D50.9 Iron deficiency anaemia, unspecified
0.060 0.940 0.000
D50-D53 Nutritional anaemias
0.060 0.940 0.000
E74 Other disorders of carbohydrate metabolism
0.059 0.941 0.001
H32 Chorioretinal disorders in diseases classified elsewhere
0.059 0.941 0.000
E70.3 Albinism
0.058 0.941 0.000
H34.1 Central retinal artery occlusion
0.058 0.942 0.000
D83 Common variable immunodeficiency
0.058 0.942 0.000
D50 Iron deficiency anaemia
0.058 0.942 0.000
E88 Other metabolic disorders
0.057 0.943 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.057 0.943 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.056 0.943 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.056 0.944 0.000
Y42.1 Thyroid hormones and substitutes
0.056 0.944 0.000
C83.6 Undifferentiated (diffuse)
0.055 0.945 0.000
C83.5 Lymphoblastic (diffuse)
0.055 0.945 0.000
C83.4 Immunoblastic (diffuse)
0.055 0.945 0.000
C83.2 Mixed small and large cell (diffuse)
0.055 0.945 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.055 0.945 0.000
H34.9 Retinal vascular occlusion, unspecified
0.055 0.945 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.054 0.946 0.000
H31.3 Choroidal haemorrhage and rupture
0.053 0.946 0.000
H34.0 Transient retinal artery occlusion
0.053 0.947 0.000
E73 Lactose intolerance
0.053 0.947 0.001
D63 Anaemia in chronic diseases classified elsewhere
0.053 0.947 0.000
Y42.4 Oral contraceptives
0.053 0.947 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.052 0.948 0.000
E70.8 Other disorders of aromatic amino-acid metabolism
0.052 0.948 0.000
E70.2 Disorders of tyrosine metabolism
0.052 0.948 0.000
E70.1 Other hyperphenylalaninaemias
0.052 0.948 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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