TreeWAS – Variant ID: rs3131643

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D64.9 Anaemia, unspecified	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
H36.0 Diabetic retinopathy	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
M35.0 Sicca syndrome [Sjogren]	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
M35 Other systemic involvement of connective tissue	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
K90 Intestinal malabsorption	1.000	0.000	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	1.000	0.000	0.000
J40-J47 Chronic lower respiratory diseases	1.000	0.000	0.000
Chapter XI Diseases of the digestive system	1.000	0.000	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	1.000	0.000	0.000
D60-D64 Aplastic and other anaemias	1.000	0.000	0.000
H30-H36 Disorders of choroid and retina	1.000	0.000	0.000
K70-K77 Diseases of liver	1.000	0.000	0.000
E14 Unspecified diabetes mellitus	1.000	0.000	0.000
E16.2 Hypoglycaemia, unspecified	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	1.000	0.000	0.000
E10.1 With ketoacidosis	1.000	0.000	0.000
D64 Other anaemias	1.000	0.000	0.000
H36 Retinal disorders in diseases classified elsewhere	1.000	0.000	0.000
E16 Other disorders of pancreatic internal secretion	1.000	0.000	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	1.000	0.000	0.000
K75 Other inflammatory liver diseases	1.000	0.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000	0.000
D80-D89 Certain disorders involving the immune mechanism	1.000	0.000	0.000
Chapter IX Diseases of the circulatory system	0.999	0.001	0.000
J44 Other chronic obstructive pulmonary disease	0.999	0.001	0.000
E14.3 With ophthalmic complications	0.999	0.001	0.000
K75.4 Autoimmune hepatitis	0.999	0.001	0.000
J45 Asthma	0.999	0.001	0.000
K90-K93 Other diseases of the digestive system	0.999	0.001	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.999	0.001	0.000
E11 Non-insulin-dependent diabetes mellitus	0.999	0.001	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.999	0.001	0.000
D69 Purpura and other haemorrhagic conditions	0.998	0.002	0.000
D86 Sarcoidosis	0.998	0.002	0.000
E27.1 Primary adrenocortical insufficiency	0.998	0.002	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.998	0.002	0.000
Chapter I Certain infectious and parasitic diseases	0.998	0.002	0.000
E20-E35 Disorders of other endocrine glands	0.998	0.002	0.000
E27 Other disorders of adrenal gland	0.998	0.002	0.000
J45.9 Asthma, unspecified	0.997	0.003	0.000
N00-N08 Glomerular diseases	0.997	0.003	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.997	0.003	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.996	0.004	0.000
I73 Other peripheral vascular diseases	0.996	0.004	0.000
E10.2 With renal complications	0.996	0.004	0.000
D70 Agranulocytosis	0.995	0.005	0.000
D86.9 Sarcoidosis, unspecified	0.995	0.005	0.000
M24 Other specific joint derangements	0.994	0.006	0.000
N04 Nephrotic syndrome	0.993	0.007	0.000
C85.1 B-cell lymphoma, unspecified	0.992	0.008	0.000
I74 Arterial embolism and thrombosis	0.991	0.009	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.990	0.010	0.000
B35-B49 Mycoses	0.990	0.010	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.989	0.011	0.000
K50-K52 Noninfective enteritis and colitis	0.988	0.011	0.000
K52 Other non-infective gastro-enteritis and colitis	0.988	0.011	0.000
Chapter XIV Diseases of the genitourinary system	0.988	0.012	0.000
N04.9 Unspecified	0.987	0.013	0.000
L20-L30 Dermatitis and eczema	0.986	0.014	0.000
A30-A49 Other bacterial diseases	0.984	0.016	0.000
D69.6 Thrombocytopenia, unspecified	0.984	0.016	0.000
H43-H45 Disorders of vitreous body and globe	0.983	0.017	0.000
E10.4 With neurological complications	0.983	0.017	0.000
M15-M19 Arthrosis	0.982	0.018	0.000
B37 Candidiasis	0.981	0.019	0.000
A41 Other septicaemia	0.980	0.020	0.000
C91 Lymphoid leukaemia	0.980	0.020	0.000
D68 Other coagulation defects	0.979	0.021	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.979	0.021	0.000
C81 Hodgkin's disease	0.979	0.021	0.000
N05 Unspecified nephritic syndrome	0.978	0.022	0.000
K90.9 Intestinal malabsorption, unspecified	0.978	0.022	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.978	0.022	0.000
A41.9 Septicaemia, unspecified	0.977	0.023	0.000
N17-N19 Renal failure	0.977	0.023	0.000
I73.0 Raynaud's syndrome	0.976	0.024	0.000
E11.9 Without complications	0.975	0.025	0.000
M24.1 Other articular cartilage disorders	0.975	0.025	0.000
H43 Disorders of vitreous body	0.975	0.025	0.000
D61 Other aplastic anaemias	0.974	0.026	0.000
M20.1 Hallux valgus (acquired)	0.000	0.026	0.974
D50-D53 Nutritional anaemias	0.973	0.027	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.973	0.027	0.000
M18 Arthrosis of first carpometacarpal joint	0.972	0.028	0.000
N18 Chronic renal failure	0.971	0.029	0.000
E89.0 Postprocedural hypothyroidism	0.969	0.031	0.000
C83.3 Large cell (diffuse)	0.968	0.032	0.000
L50-L54 Urticaria and erythema	0.967	0.033	0.000
K74 Fibrosis and cirrhosis of liver	0.965	0.035	0.000
E06 Thyroiditis	0.965	0.035	0.000
M34 Systemic sclerosis	0.965	0.035	0.000
H43.1 Vitreous haemorrhage	0.965	0.035	0.000
E70-E90 Metabolic disorders	0.965	0.035	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.964	0.036	0.000
I73.9 Peripheral vascular disease, unspecified	0.962	0.038	0.000
J33 Nasal polyp	0.962	0.038	0.000
N18.3 Chronic kidney disease, stage 3	0.961	0.039	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.961	0.039	0.000
M20 Acquired deformities of fingers and toes	0.002	0.042	0.956
C91.1 Chronic lymphocytic leukaemia	0.958	0.042	0.000
J30-J39 Other diseases of upper respiratory tract	0.958	0.042	0.000
L10-L14 Bullous disorders	0.957	0.043	0.000
J33.0 Polyp of nasal cavity	0.956	0.044	0.000
B37.9 Candidiasis, unspecified	0.953	0.047	0.000
M20.5 Other deformities of toe(s) (acquired)	0.000	0.048	0.952
D50 Iron deficiency anaemia	0.952	0.048	0.000
J46 Status asthmaticus	0.951	0.049	0.000
K73 Chronic hepatitis, not elsewhere classified	0.947	0.053	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.947	0.053	0.000
I10-I15 Hypertensive diseases	0.947	0.053	0.000
J33.9 Nasal polyp, unspecified	0.946	0.054	0.000
I71 Aortic aneurysm and dissection	0.944	0.056	0.000
E11.3 With ophthalmic complications	0.944	0.056	0.000
D61.9 Aplastic anaemia, unspecified	0.944	0.056	0.000
Chapter XX External causes of morbidity and mortality	0.942	0.058	0.000
M35.3 Polymyalgia rheumatica	0.938	0.062	0.000
C81.9 Hodgkin's disease, unspecified	0.938	0.062	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.937	0.063	0.000
E11.1 With ketoacidosis	0.936	0.064	0.000
E14.9 Without complications	0.935	0.065	0.000
B37.8 Candidiasis of other sites	0.934	0.066	0.000
H25-H28 Disorders of lens	0.933	0.067	0.000
E06.3 Autoimmune thyroiditis	0.931	0.069	0.000
I12 Hypertensive renal disease	0.931	0.069	0.000
L13 Other bullous disorders	0.928	0.072	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.928	0.072	0.000
K74.6 Other and unspecified cirrhosis of liver	0.927	0.073	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.926	0.074	0.000
K60.2 Anal fissure, unspecified	0.924	0.076	0.000
N05.2 Diffuse membranous glomerulonephritis	0.923	0.077	0.000
I12.9 Hypertensive renal disease without renal failure	0.923	0.077	0.000
J45.0 Predominantly allergic asthma	0.921	0.079	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.920	0.080	0.000
H26 Other cataract	0.919	0.081	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.918	0.082	0.000
K75.8 Other specified inflammatory liver diseases	0.918	0.082	0.000
Chapter II Neoplasms	0.916	0.084	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.914	0.086	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.914	0.086	0.000
H26.9 Cataract, unspecified	0.914	0.086	0.000
H34 Retinal vascular occlusions	0.911	0.089	0.000
H06.2 Dysthyroid exophthalmos	0.911	0.089	0.000
C83.0 Small cell (diffuse)	0.911	0.089	0.000
L52 Erythema nodosum	0.910	0.090	0.000
D80 Immunodeficiency with predominantly antibody defects	0.910	0.090	0.000
H43.8 Other disorders of vitreous body	0.910	0.090	0.000
E50-E64 Other nutritional deficiencies	0.910	0.090	0.000
E11.5 With peripheral circulatory complications	0.910	0.090	0.000
L28 Lichen simplex chronicus and prurigo	0.907	0.093	0.000
L13.0 Dermatitis herpetiformis	0.907	0.093	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.906	0.094	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.906	0.094	0.000
D50.9 Iron deficiency anaemia, unspecified	0.906	0.094	0.000
H05 Disorders of orbit	0.905	0.095	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.904	0.096	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.904	0.096	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.903	0.097	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.902	0.098	0.000
M15 Polyarthrosis	0.899	0.101	0.000
L27 Dermatitis due to substances taken internally	0.898	0.102	0.000
I60-I69 Cerebrovascular diseases	0.897	0.103	0.000
M60-M63 Disorders of muscles	0.896	0.104	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.893	0.107	0.000
M32 Systemic lupus erythematosus	0.893	0.107	0.000
I63 Cerebral infarction	0.891	0.109	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.890	0.110	0.000
D68.8 Other specified coagulation defects	0.888	0.112	0.000
J84 Other interstitial pulmonary diseases	0.886	0.114	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.885	0.115	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.883	0.117	0.000
L30 Other dermatitis	0.883	0.117	0.000
C88 Malignant immunoproliferative diseases	0.882	0.118	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.881	0.119	0.000
H30 Chorioretinal inflammation	0.880	0.119	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.880	0.120	0.000
W00-W19 Falls	0.878	0.122	0.000
I77 Other disorders of arteries and arterioles	0.877	0.123	0.000
V20-V29 Motorcycle rider injured in transport accident	0.874	0.126	0.000
D69.4 Other primary thrombocytopenia	0.874	0.126	0.000
R63.4 Abnormal weight loss	0.873	0.127	0.000
W19 Unspecified fall	0.872	0.128	0.000
D68.6 Other Thrombophilia	0.872	0.128	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.864	0.136	0.000
B25-B34 Other viral diseases	0.864	0.136	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.863	0.137	0.000
D50.8 Other iron deficiency anaemias	0.863	0.137	0.000
W19.9 Unspecified place	0.862	0.138	0.000
M20.4 Other hammer toe(s) (acquired)	0.000	0.139	0.861
L94 Other localised connective tissue disorders	0.859	0.141	0.000
M35.7 Hypermobility syndrome	0.858	0.142	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.858	0.142	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.857	0.143	0.000
Chapter VIII Diseases of the ear and mastoid process	0.857	0.143	0.000
C81.1 Nodular sclerosis	0.856	0.144	0.000
E14.2 Withrenal complications	0.854	0.146	0.000
N08.5 Glomerular disorders in systemic connective tissue disorders	0.851	0.149	0.000
E07 Other disorders of thyroid	0.851	0.149	0.000
H04 Disorders of lachrymal system	0.850	0.150	0.000
H26.1 Traumatic cataract	0.848	0.152	0.000
Y42.7 Androgens and anabolic congeners	0.848	0.152	0.000
D55-D59 Haemolytic anaemias	0.847	0.153	0.000
D69.2 Other nonthrombocytopenic purpura	0.847	0.153	0.000
I74.8 Embolism and thrombosis of other arteries	0.840	0.160	0.000
D68.0 Von Willebrand's disease	0.839	0.161	0.000
K75.9 Inflammatory liver disease, unspecified	0.839	0.161	0.000
V40-V49 Car occupant injured in transport accident	0.839	0.161	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.838	0.162	0.000
K74.3 Primary biliary cirrhosis	0.838	0.162	0.000
E14.1 With ketoacidosis	0.838	0.162	0.000
M35.1 Other overlap syndromes	0.837	0.163	0.000
M34.8 Other forms of systemic sclerosis	0.836	0.164	0.000
L28.0 Lichen simplex chronicus	0.835	0.165	0.000
L93 Lupus erythematosus	0.834	0.166	0.000
J95-J99 Other diseases of the respiratory system	0.834	0.166	0.000
B44 Aspergillosis	0.834	0.166	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.833	0.167	0.000
M17 Gonarthrosis [arthrosis of knee]	0.833	0.167	0.000
E10.5 With peripheral circulatory complications	0.832	0.168	0.000
H90-H95 Other disorders of ear	0.831	0.169	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.830	0.170	0.000
N05.9 Unspecified	0.829	0.171	0.000
B25 Cytomegaloviral disease	0.829	0.171	0.000
N05.1 Focal and segmental glomerular lesions	0.829	0.171	0.000
L50 Urticaria	0.827	0.173	0.000
A63.0 Anogenital (venereal) warts	0.827	0.173	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.825	0.175	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.825	0.175	0.000
E10.7 With multiple complications	0.824	0.176	0.000
E24 Cushing's syndrome	0.823	0.177	0.000
H90 Conductive and sensorineural hearing loss	0.822	0.178	0.000
E10.0 With coma	0.822	0.178	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.821	0.179	0.000
L20 Atopic dermatitis	0.821	0.179	0.000
D86.8 Sarcoidosis of other and combined sites	0.819	0.181	0.000
J30 Vasomotor and allergic rhinitis	0.819	0.181	0.000
M34.1 CR(E)ST syndrome	0.819	0.181	0.000
N18.0 End-stage renal disease	0.816	0.184	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.816	0.184	0.000
M86-M90 Other osteopathies	0.814	0.186	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.814	0.186	0.000
H34.8 Other retinal vascular occlusions	0.813	0.187	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.812	0.188	0.000
M24.2 Disorder of ligament	0.810	0.190	0.000
A41.2 Septicaemia due to unspecified staphylococcus	0.809	0.191	0.000
E14.8 With unspecified complications	0.809	0.191	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.808	0.192	0.000
L95 Vasculitis limited to skin, not elsewhere classified	0.808	0.192	0.000
M34.0 Progressive systemic sclerosis	0.807	0.193	0.000
I11 Hypertensive heart disease	0.807	0.193	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.804	0.196	0.000
D83 Common variable immunodeficiency	0.803	0.197	0.000
N17 Acute renal failure	0.803	0.197	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.802	0.198	0.000
B37.7 Candidal septicaemia	0.801	0.199	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.801	0.199	0.000
E10.8 With unspecified complications	0.800	0.200	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.799	0.201	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.798	0.201	0.000
D69.9 Haemorrhagic condition, unspecified	0.798	0.202	0.000
N18.9 Chronic renal failure, unspecified	0.797	0.203	0.000
M24.5 Contracture of joint	0.796	0.204	0.000
H30.9 Chorioretinal inflammation, unspecified	0.795	0.205	0.000
K60 Fissure and fistula of anal and rectal regions	0.795	0.205	0.000
D69.5 Secondary thrombocytopenia	0.794	0.206	0.000
K72 Hepatic failure, not elsewhere classified	0.794	0.206	0.000
M34.9 Systemic sclerosis, unspecified	0.794	0.206	0.000
M21 Other acquired deformities of limbs	0.793	0.207	0.000
M17.1 Other primary gonarthrosis	0.792	0.208	0.000
L30.9 Dermatitis, unspecified	0.792	0.208	0.000
I77.1 Stricture of artery	0.792	0.208	0.000
C91.9 Lymphoid leukaemia, unspecified	0.792	0.208	0.000
B25.9 Cytomegaloviral disease, unspecified	0.791	0.209	0.000
I63.8 Other cerebral infarction	0.791	0.209	0.000
I77.6 Arteritis, unspecified	0.790	0.210	0.000
E31 Polyglandular dysfunction	0.790	0.210	0.000
K90.8 Other intestinal malabsorption	0.790	0.210	0.000
N04.2 Diffuse membranous glomerulonephritis	0.789	0.210	0.000
D86.3 Sarcoidosis of skin	0.789	0.211	0.000
D61.1 Drug-induced aplastic anaemia	0.787	0.213	0.000
M60 Myositis	0.787	0.213	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.787	0.213	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.787	0.213	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.786	0.214	0.000
J37 Chronic laryngitis and laryngotracheitis	0.785	0.215	0.000
I63.9 Cerebral infarction, unspecified	0.783	0.217	0.000
M20.3 Other deformity of hallux (acquired)	0.001	0.217	0.782
D68.2 Hereditary deficiency of other clotting factors	0.780	0.220	0.000
L92.0 Granuloma annulare	0.778	0.222	0.000
E20 Hypoparathyroidism	0.777	0.223	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.776	0.224	0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.774	0.226	0.000
M24.7 Protrusio acetabuli	0.774	0.226	0.000
D73 Diseases of spleen	0.774	0.226	0.000
E83.1 Disorders of iron metabolism	0.000	0.227	0.773
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.773	0.227	0.000
C04 Malignant neoplasm of floor of mouth	0.773	0.227	0.000
H35 Other retinal disorders	0.771	0.229	0.000
D86.1 Sarcoidosis of lymph nodes	0.771	0.229	0.000
C07 Malignant neoplasm of parotid gland	0.771	0.229	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.771	0.229	0.000
C92 Myeloid leukaemia	0.771	0.229	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.771	0.229	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.771	0.229	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.770	0.230	0.000
H05.2 Exophthalmic conditions	0.768	0.232	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.768	0.232	0.000
H05.8 Other disorders of orbit	0.766	0.234	0.000
N18.4 Chronic kidney disease, stage 4	0.765	0.235	0.000
E06.9 Thyroiditis, unspecified	0.765	0.235	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.764	0.236	0.000
E11.8 With unspecified complications	0.763	0.237	0.000
K73.9 Chronic hepatitis, unspecified	0.762	0.238	0.000
N04.1 Focal and segmental glomerular lesions	0.762	0.238	0.000
M00-M03 Infectious arthropathies	0.761	0.239	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.760	0.240	0.000
H04.1 Other disorders of lachrymal gland	0.760	0.240	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.757	0.243	0.000
B49 Unspecified mycosis	0.757	0.243	0.000
D50.1 Sideropenic dysphagia	0.756	0.244	0.000
C84.5 Other and unspecified T-cell lymphomas	0.756	0.244	0.000
E07.8 Other specified disorders of thyroid	0.755	0.244	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.755	0.245	0.000
M80-M85 Disorders of bone density and structure	0.755	0.245	0.000
M86 Osteomyelitis	0.755	0.245	0.000
D86.0 Sarcoidosis of lung	0.754	0.246	0.000
D51 Vitamin B12 deficiency anaemia	0.754	0.246	0.000
L93.0 Discoid lupus erythematosus	0.754	0.246	0.000
E22 Hyperfunction of pituitary gland	0.752	0.247	0.000
C83.7 Burkitt's tumour	0.752	0.248	0.000
C83.1 Small cleaved cell (diffuse)	0.751	0.249	0.000
M24.6 Ankylosis of joint	0.750	0.249	0.000
H90.2 Conductive hearing loss, unspecified	0.750	0.250	0.000
H04.4 Chronic inflammation of lachrymal passages	0.749	0.251	0.000
H35.8 Other specified retinal disorders	0.748	0.252	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.748	0.252	0.000
H04.8 Other disorders of lachrymal system	0.747	0.253	0.000
L53 Other erythematous conditions	0.747	0.253	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.746	0.254	0.000
A48 Other bacterial diseases, not elsewhere classified	0.746	0.254	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.745	0.255	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.745	0.255	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.744	0.255	0.000
C34 Malignant neoplasm of bronchus and lung	0.744	0.256	0.000
H34.2 Other retinal artery occlusions	0.743	0.257	0.000
E88 Other metabolic disorders	0.742	0.258	0.000
E55 Vitamin D deficiency	0.742	0.258	0.000
E14.5 With peripheral circulatory complications	0.741	0.258	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.740	0.260	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.739	0.261	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.739	0.261	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.738	0.262	0.000
E11.6 With other specified complications	0.738	0.262	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.738	0.262	0.000
E14.6 With other specified complications	0.738	0.262	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.737	0.262	0.000
I05-I09 Chronic rheumatic heart diseases	0.737	0.263	0.000
E40-E46 Malnutrition	0.736	0.264	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.736	0.264	0.000
H90.3 Sensorineural hearing loss, bilateral	0.736	0.264	0.000
J41 Simple and mucopurulent chronic bronchitis	0.736	0.264	0.000
D62 Acute posthaemorrhagic anaemia	0.735	0.265	0.000
E11.2 With renal complications	0.735	0.265	0.000
Y52 Agents primarily affecting the cardiovascular system	0.735	0.265	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.734	0.266	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.734	0.266	0.000
L25 Unspecified contact dermatitis	0.734	0.266	0.000
C81.2 Mixed cellularity	0.733	0.267	0.000
E10.6 With other specified complications	0.733	0.267	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.733	0.267	0.000
N10-N16 Renal tubulo-interstitial diseases	0.733	0.267	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.733	0.267	0.000
H31 Other disorders of choroid	0.731	0.269	0.000
D53 Other nutritional anaemias	0.730	0.270	0.000
D59 Acquired haemolytic anaemia	0.730	0.270	0.000
I74.5 Embolism and thrombosis of iliac artery	0.729	0.271	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.729	0.271	0.000
L81 Other disorders of pigmentation	0.728	0.272	0.000
C02.9 Tongue, unspecified	0.728	0.272	0.000
Y42.2 Antithyroid drugs	0.728	0.272	0.000
W20-W49 Exposure to inanimate mechanical forces	0.728	0.272	0.000
B15-B19 Viral hepatitis	0.728	0.272	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.726	0.274	0.000
H05.0 Acute inflammation of orbit	0.726	0.274	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.726	0.274	0.000
B36 Other superficial mycoses	0.726	0.274	0.000
C91.0 Acute lymphoblastic leukaemia	0.725	0.275	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.725	0.275	0.000
B37.2 Candidiasis of skin and nail	0.725	0.275	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.725	0.275	0.000
E53 Deficiency of other B group vitamins	0.725	0.275	0.000
M60.9 Myositis, unspecified	0.725	0.275	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.724	0.276	0.000
L27.2 Dermatitis due to ingested food	0.723	0.277	0.000
D68.1 Hereditary factor XI deficiency	0.722	0.278	0.000
M62 Other disorders of muscle	0.722	0.278	0.000
D84 Other immunodeficiencies	0.722	0.278	0.000
J33.8 Other polyp of sinus	0.722	0.278	0.000
C93 Monocytic leukaemia	0.721	0.279	0.000
C81.0 Lymphocytic predominance	0.720	0.280	0.000
L50.1 Idiopathic urticaria	0.720	0.280	0.000
K74.5 Biliary cirrhosis, unspecified	0.720	0.280	0.000
M65-M68 Disorders of synovium and tendon	0.720	0.280	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.719	0.281	0.000
W75-W84 Other accidental threats to breathing	0.719	0.281	0.000
D61.0 Constitutional aplastic anaemia	0.719	0.281	0.000
E74 Other disorders of carbohydrate metabolism	0.718	0.282	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.718	0.282	0.000
E51 Thiamine deficiency	0.718	0.282	0.000
L23 Allergic contact dermatitis	0.717	0.283	0.000
C95 Leukaemia of unspecified cell type	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.717	0.283	0.000
M35.8 Other specified systemic involvement of connective tissue	0.717	0.283	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.717	0.283	0.000
M35.5 Multifocal fibrosclerosis	0.717	0.283	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.717	0.283	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.717	0.283	0.000
C94 Other leukaemias of specified cell type	0.717	0.283	0.000
C86 Other specified types of T/NK-cell lymphoma	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.717	0.283	0.000
C85.0 Lymphosarcoma	0.717	0.283	0.000
K90.3 Pancreatic steatorrhoea	0.717	0.283	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.717	0.283	0.000
K90.1 Tropical sprue	0.717	0.283	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.717	0.283	0.000
K77 Liver disorders in diseases classified elsewhere	0.717	0.283	0.000
K71 Toxic liver disease	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
E14.7 With multiple complications	0.717	0.283	0.000
E14.0 With coma	0.717	0.283	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.717	0.283	0.000
D64.4 Congenital dyserythropoietic anaemia	0.717	0.283	0.000
D64.3 Other sideroblastic anaemias	0.717	0.283	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.717	0.283	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.717	0.283	0.000
D64.0 Hereditary sideroblastic anaemia	0.717	0.283	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.717	0.283	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.717	0.283	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.717	0.283	0.000
E16.4 Abnormal secretion of gastrin	0.717	0.283	0.000
E16.3 Increased secretion of glucagon	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.717	0.283	0.000
D67 Hereditary factor IX deficiency	0.717	0.283	0.000
K75.2 Nonspecific reactive hepatitis	0.717	0.283	0.000
K75.1 Phlebitis of portal vein	0.717	0.283	0.000
D82 Immunodeficiency associated with other major defects	0.717	0.283	0.000
D81 Combined immunodeficiencies	0.717	0.283	0.000
I00-I02 Acute rheumatic fever	0.717	0.283	0.000
J45.8 Mixed asthma	0.716	0.284	0.000
J45.1 Nonallergic asthma	0.716	0.284	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.716	0.284	0.000
E11.7 With multiple complications	0.716	0.284	0.000
D69.8 Other specified haemorrhagic conditions	0.716	0.284	0.000
D69.1 Qualitative platelet defects	0.716	0.284	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.716	0.284	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.715	0.284	0.000
A75-A79 Rickettsioses	0.715	0.284	0.000
A70-A74 Other diseases caused by chlamydiae	0.715	0.284	0.000
A20-A28 Certain zoonotic bacterial diseases	0.715	0.284	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.715	0.284	0.000
E32 Diseases of thymus	0.715	0.284	0.000
E30 Disorders of puberty, not elsewhere classified	0.715	0.284	0.000
E25 Adrenogenital disorders	0.715	0.284	0.000
C34.3 Lower lobe, bronchus or lung	0.715	0.285	0.000
E27.5 Adrenomedullary hyperfunction	0.715	0.285	0.000
E27.0 Other adrenocortical overactivity	0.715	0.285	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.715	0.285	0.000
N06 Isolated proteinuria with specified morphological lesion	0.715	0.285	0.000
N01 Rapidly progressive nephritic syndrome	0.715	0.285	0.000
N00 Acute nephritic syndrome	0.715	0.285	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations