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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3131785
log Bayes Factor = 78.7239
Chromosome 6   position 30,901,895  (GRCh37) Explore rs3131785 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
L40.0 Psoriasis vulgaris
0.000 0.018 0.982
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.088 0.912
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.088 0.912
E05.9 Thyrotoxicosis, unspecified
0.000 0.092 0.908
E10-E14 Diabetes mellitus
0.000 0.103 0.897
E10 Insulin-dependent diabetes mellitus
0.000 0.111 0.889
E00-E07 Disorders of thyroid gland
0.000 0.116 0.884
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.119 0.881
E10.2 With renal complications
0.000 0.133 0.867
L40.8 Other psoriasis
0.000 0.136 0.864
E10.3 With ophthalmic complications
0.000 0.140 0.860
L40.1 Generalised pustular psoriasis
0.000 0.154 0.846
E14 Unspecified diabetes mellitus
0.000 0.165 0.835
E13 Other specified diabetes mellitus
0.000 0.170 0.830
E11 Non-insulin-dependent diabetes mellitus
0.000 0.203 0.797
E13.9 Without complications
0.000 0.222 0.778
E10.1 With ketoacidosis
0.000 0.225 0.775
E20-E35 Disorders of other endocrine glands
0.000 0.229 0.771
E11.5 With peripheral circulatory complications
0.000 0.234 0.766
L40.4 Guttate psoriasis
0.000 0.235 0.765
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.267 0.733
E11.6 With other specified complications
0.000 0.270 0.730
E11.1 With ketoacidosis
0.000 0.271 0.729
E14.4 With neurological complications
0.000 0.275 0.725
E40-E46 Malnutrition
0.000 0.280 0.720
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.293 0.707
E23 Hypofunction and other disorders of pituitary gland
0.000 0.296 0.704
E29 Testicular dysfunction
0.000 0.296 0.704
E24 Cushing's syndrome
0.000 0.297 0.703
E06 Thyroiditis
0.000 0.303 0.697
E14.2 Withrenal complications
0.000 0.305 0.695
E14.8 With unspecified complications
0.000 0.317 0.683
K90 Intestinal malabsorption
0.000 0.323 0.677
L40.3 Pustulosis palmaris et plantaris
0.000 0.324 0.676
E29.1 Testicular hypofunction
0.000 0.345 0.655
E05.5 Thyroid crisis or storm
0.000 0.346 0.654
E05.4 Thyrotoxicosis factitia
0.000 0.346 0.654
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.346 0.654
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.346 0.654
E12 Malnutrition-related diabetes mellitus
0.000 0.357 0.643
E14.1 With ketoacidosis
0.000 0.357 0.643
E14.3 With ophthalmic complications
0.000 0.357 0.643
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.366 0.634
E00 Congenital iodine-deficiency syndrome
0.000 0.366 0.634
E10.7 With multiple complications
0.000 0.368 0.632
E14.5 With peripheral circulatory complications
0.000 0.370 0.630
E03 Other hypothyroidism
0.000 0.373 0.627
E16 Other disorders of pancreatic internal secretion
0.000 0.373 0.627
E27 Other disorders of adrenal gland
0.000 0.376 0.624
E24.0 Pituitary-dependent Cushing's disease
0.000 0.380 0.620
E13.3 With ophthalmic complications
0.000 0.383 0.617
E24.2 Drug-induced Cushing's syndrome
0.000 0.384 0.616
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.390 0.610
E10.4 With neurological complications
0.000 0.391 0.609
E05.8 Other thyrotoxicosis
0.000 0.392 0.608
E23.6 Other disorders of pituitary gland
0.000 0.393 0.607
K90.9 Intestinal malabsorption, unspecified
0.000 0.394 0.606
E46 Unspecified protein-energy malnutrition
0.000 0.395 0.605
E11.2 With renal complications
0.000 0.399 0.601
E14.7 With multiple complications
0.000 0.401 0.599
E14.0 With coma
0.000 0.401 0.599
E13.8 With unspecified complications
0.000 0.405 0.595
E13.7 With multiple complications
0.000 0.405 0.595
E13.6 With other specified complications
0.000 0.405 0.595
E13.5 With peripheral circulatory complications
0.000 0.405 0.595
E13.4 With neurological complications
0.000 0.405 0.595
E13.2 With renal complications
0.000 0.405 0.595
E13.1 With ketoacidosis
0.000 0.405 0.595
E13.0 With coma
0.000 0.405 0.595
E23.2 Diabetes insipidus
0.000 0.418 0.582
E25 Adrenogenital disorders
0.000 0.420 0.580
E14.6 With other specified complications
0.000 0.424 0.576
E06.9 Thyroiditis, unspecified
0.000 0.426 0.574
E11.7 With multiple complications
0.000 0.428 0.571
E10.9 Without complications
0.000 0.438 0.562
E11.0 With coma
0.000 0.444 0.556
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.447 0.553
E32 Diseases of thymus
0.000 0.447 0.553
E30 Disorders of puberty, not elsewhere classified
0.000 0.447 0.553
E31 Polyglandular dysfunction
0.000 0.448 0.552
E27.9 Disorder of adrenal gland, unspecified
0.000 0.449 0.551
E16.2 Hypoglycaemia, unspecified
0.000 0.456 0.544
E23.0 Hypopituitarism
0.000 0.462 0.538
E06.5 Other chronic thyroiditis
0.000 0.467 0.533
E03.8 Other specified hypothyroidism
0.000 0.469 0.531
E15 Nondiabetic hypoglycaemic coma
0.000 0.474 0.525
E10.6 With other specified complications
0.000 0.476 0.523
E06.1 Subacute thyroiditis
0.000 0.480 0.520
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.481 0.519
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.483 0.516
E45 Retarded development following protein-energy malnutrition
0.000 0.483 0.516
E43 Unspecified severe protein-energy malnutrition
0.000 0.483 0.516
E42 Marasmic kwashiorkor
0.000 0.483 0.516
E41 Nutritional marasmus
0.000 0.483 0.516
E40 Kwashiorkor
0.000 0.483 0.516
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.484 0.516
M07.3 Other psoriatic arthropathies
0.000 0.487 0.513
E10.0 With coma
0.000 0.490 0.510
E16.1 Other hypoglycaemia
0.000 0.490 0.510
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.491 0.509
E23.7 Disorder of pituitary gland, unspecified
0.000 0.493 0.507
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.495 0.504
E23.1 Drug-induced hypopituitarism
0.000 0.495 0.504
E29.9 Testicular dysfunction, unspecified
0.000 0.495 0.504
E29.8 Other testicular dysfunction
0.000 0.495 0.504
E29.0 Testicular hyperfunction
0.000 0.495 0.504
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.496 0.504
E24.3 Ectopic ACTH syndrome
0.000 0.496 0.504
E24.1 Nelson's syndrome
0.000 0.496 0.504
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.498 0.501
E06.4 Drug-induced thyroiditis
0.000 0.500 0.500
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.500 0.500
E06.0 Acute thyroiditis
0.000 0.500 0.500
K90.8 Other intestinal malabsorption
0.000 0.506 0.494
E24.8 Other Cushing's syndrome
0.000 0.512 0.488
K90.3 Pancreatic steatorrhoea
0.000 0.514 0.486
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.514 0.486
K90.1 Tropical sprue
0.000 0.514 0.486
E20 Hypoparathyroidism
0.000 0.516 0.484
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.517 0.483
E26 Hyperaldosteronism
0.000 0.520 0.479
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.522 0.478
E07 Other disorders of thyroid
0.000 0.526 0.474
E50-E64 Other nutritional deficiencies
0.000 0.531 0.468
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.536 0.464
E12.9 Without complications
0.000 0.539 0.461
E12.8 With unspecified complications
0.000 0.539 0.461
E12.7 With multiple complications
0.000 0.539 0.461
E12.6 With other specified complications
0.000 0.539 0.461
E12.5 With peripheral circulatory complications
0.000 0.539 0.461
E12.4 With neurological complications
0.000 0.539 0.461
E12.3 With ophthalmic complications
0.000 0.539 0.461
E12.2 With renal complications
0.000 0.539 0.461
E12.1 With ketoacidosis
0.000 0.539 0.461
E12.0 With coma
0.000 0.539 0.461
E24.9 Cushing's syndrome, unspecified
0.000 0.544 0.456
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.545 0.454
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.545 0.454
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.545 0.454
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.545 0.454
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.545 0.454
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.545 0.454
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.545 0.454
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.545 0.454
E03.5 Myxoedema coma
0.000 0.550 0.450
E03.4 Atrophy of thyroid (acquired)
0.000 0.550 0.450
E03.3 Postinfectious hypothyroidism
0.000 0.550 0.450
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.550 0.449
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.550 0.449
E16.4 Abnormal secretion of gastrin
0.000 0.550 0.449
E16.3 Increased secretion of glucagon
0.000 0.550 0.449
E27.5 Adrenomedullary hyperfunction
0.000 0.553 0.447
E27.0 Other adrenocortical overactivity
0.000 0.553 0.447
E03.1 Congenital hypothyroidism without goitre
0.000 0.553 0.447
E11.8 With unspecified complications
0.000 0.554 0.446
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.556 0.444
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.557 0.442
E14.9 Without complications
0.000 0.561 0.439
E27.1 Primary adrenocortical insufficiency
0.000 0.561 0.439
E61 Deficiency of other nutrient elements
0.000 0.569 0.431
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.570 0.430
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.579 0.421
R10.1 Pain localised to upper abdomen
0.000 0.582 0.418
E25.9 Adrenogenital disorder, unspecified
0.000 0.584 0.416
E25.8 Other adrenogenital disorders
0.000 0.584 0.416
E06.3 Autoimmune thyroiditis
0.000 0.589 0.411
E22 Hyperfunction of pituitary gland
0.000 0.602 0.398
E11.4 With neurological complications
0.000 0.602 0.398
E30.9 Disorder of puberty, unspecified
0.000 0.603 0.396
E30.8 Other disorders of puberty
0.000 0.603 0.396
E30.1 Precocious puberty
0.000 0.603 0.396
E30.0 Delayed puberty
0.000 0.603 0.396
E32.9 Disease of thymus, unspecified
0.000 0.603 0.396
E32.8 Other diseases of thymus
0.000 0.603 0.396
E32.1 Abscess of thymus
0.000 0.603 0.396
E32.0 Persistent hyperplasia of thymus
0.000 0.603 0.396
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.603 0.396
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.603 0.396
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.603 0.396
E31.9 Polyglandular dysfunction, unspecified
0.000 0.604 0.396
E31.8 Other polyglandular dysfunction
0.000 0.604 0.396
E31.1 Polyglandular hyperfunction
0.000 0.604 0.396
E31.0 Autoimmune polyglandular failure
0.000 0.604 0.395
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.605 0.395
E61.2 Magnesium deficiency
0.000 0.615 0.385
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.620 0.380
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.627 0.373
E44.1 Mild protein-energy malnutrition
0.000 0.629 0.370
E44.0 Moderate protein-energy malnutrition
0.000 0.629 0.370
M07.38 Other psoriatic arthropathies (Other)
0.000 0.632 0.368
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.632 0.368
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.632 0.368
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.632 0.368
E61.1 Iron deficiency
0.000 0.639 0.361
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.642 0.357
E27.8 Other specified disorders of adrenal gland
0.000 0.646 0.354
E34 Other endocrine disorders
0.000 0.652 0.347
E20.1 Pseudohypoparathyroidism
0.000 0.653 0.347
E20.0 Idiopathic hypoparathyroidism
0.000 0.653 0.347
E26.8 Other hyperaldosteronism
0.000 0.656 0.344
E26.1 Secondary hyperaldosteronism
0.000 0.656 0.344
E26.9 Hyperaldosteronism, unspecified
0.000 0.657 0.343
E07.1 Dyshormogenetic goitre
0.000 0.660 0.340
E07.0 Hypersecretion of calcitonin
0.000 0.660 0.340
E51 Thiamine deficiency
0.000 0.660 0.339
E07.8 Other specified disorders of thyroid
0.000 0.661 0.338
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.664 0.336
E63 Other nutritional deficiencies
0.000 0.664 0.336
E50 Vitamin A deficiency
0.000 0.664 0.336
E60 Dietary zinc deficiency
0.000 0.664 0.336
E59 Dietary selenium deficiency
0.000 0.664 0.336
E52 Niacin deficiency [pellagra]
0.000 0.664 0.336
E58 Dietary calcium deficiency
0.000 0.670 0.330
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.671 0.329
E27.2 Addisonian crisis
0.000 0.675 0.325
E56 Other vitamin deficiencies
0.000 0.676 0.324
E20.9 Hypoparathyroidism, unspecified
0.000 0.677 0.323
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.680 0.319
E10.5 With peripheral circulatory complications
0.001 0.689 0.310
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.690 0.310
E20.8 Other hypoparathyroidism
0.000 0.690 0.309
E61.9 Deficiency of nutrient element, unspecified
0.000 0.691 0.309
E61.8 Deficiency of other specified nutrient elements
0.000 0.691 0.309
E61.7 Deficiency of multiple nutrient elements
0.000 0.691 0.309
E61.6 Vanadium deficiency
0.000 0.691 0.309
E61.5 Molybdenum deficiency
0.000 0.691 0.309
E61.4 Chromium deficiency
0.000 0.691 0.309
E61.3 Manganese deficiency
0.000 0.691 0.309
E61.0 Copper deficiency
0.000 0.691 0.309
E28 Ovarian dysfunction
0.001 0.697 0.302
E21.4 Other specified disorders of parathyroid gland
0.000 0.698 0.302
E21.2 Other hyperparathyroidism
0.000 0.700 0.300
L40-L45 Papulosquamous disorders
0.000 0.705 0.295
E22.8 Other hyperfunction of pituitary gland
0.000 0.714 0.285
E26.0 Primary hyperaldosteronism
0.000 0.728 0.272
E22.1 Hyperprolactinaemia
0.000 0.731 0.269
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.747 0.253
E54 Ascorbic acid deficiency
0.000 0.748 0.252
E34.5 Androgen resistance syndrome
0.000 0.751 0.249
E34.4 Constitutional tall stature
0.000 0.751 0.249
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.751 0.249
E34.1 Other hypersecretion of intestinal hormones
0.000 0.751 0.249
E51.2 Wernicke's encephalopathy
0.000 0.753 0.247
E51.9 Thiamine deficiency, unspecified
0.000 0.756 0.243
E51.8 Other manifestations of thiamine deficiency
0.000 0.756 0.243
E51.1 Beriberi
0.000 0.756 0.243
E50.9 Vitamin A deficiency, unspecified
0.000 0.759 0.241
E50.8 Other manifestations of vitamin A deficiency
0.000 0.759 0.241
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.759 0.241
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.759 0.241
E50.5 Vitamin A deficiency with night blindness
0.000 0.759 0.241
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.759 0.241
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.759 0.241
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.759 0.241
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.759 0.241
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.759 0.241
E63.9 Nutritional deficiency, unspecified
0.000 0.759 0.241
E63.8 Other specified nutritional deficiencies
0.000 0.759 0.241
E63.1 Imbalance of constituents of food intake
0.000 0.759 0.241
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.759 0.241
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.759 0.241
E64.8 Sequelae of other nutritional deficiencies
0.000 0.759 0.241
E64.3 Sequelae of rickets
0.000 0.759 0.241
E64.2 Sequelae of vitamin C deficiency
0.000 0.759 0.241
E64.1 Sequelae of vitamin A deficiency
0.000 0.759 0.241
E64.0 Sequelae of protein-energy malnutrition
0.000 0.759 0.241
E34.3 Short stature, not elsewhere classified
0.000 0.760 0.240
E65-E68 Obesity and other hyperalimentation
0.000 0.760 0.240
M07 Psoriatic and enteropathic arthropathies
0.002 0.761 0.237
E34.8 Other specified endocrine disorders
0.000 0.763 0.237
E56.9 Vitamin deficiency, unspecified
0.000 0.767 0.232
E56.8 Deficiency of other vitamins
0.000 0.767 0.232
E56.0 Deficiency of vitamin E
0.000 0.767 0.232
E55 Vitamin D deficiency
0.000 0.774 0.225
E56.1 Deficiency of vitamin K
0.000 0.780 0.220
E28.9 Ovarian dysfunction, unspecified
0.001 0.783 0.217
E28.8 Other ovarian dysfunction
0.001 0.783 0.217
E28.1 Androgen excess
0.001 0.783 0.217
E28.0 Oestrogen excess
0.001 0.783 0.217
L44 Other papulosquamous disorders
0.000 0.787 0.212
L41 Parapsoriasis
0.000 0.788 0.212
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.788 0.212
L42 Pityriasis rosea
0.000 0.791 0.209
E34.0 Carcinoid syndrome
0.000 0.792 0.207
E28.3 Primary ovarian failure
0.001 0.812 0.187
E07.9 Disorder of thyroid, unspecified
0.000 0.817 0.183
M07.6 Other enteropathic arthropathies
0.001 0.818 0.181
R10 Abdominal and pelvic pain
0.000 0.819 0.181
E34.9 Endocrine disorder, unspecified
0.000 0.825 0.174
E67 Other hyperalimentation
0.000 0.828 0.172
E68 Sequelae of hyperalimentation
0.000 0.828 0.172
M07.5 Arthropathy in ulcerative colitis
0.001 0.828 0.170
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.001 0.828 0.170
M07.2 Psoriatic spondylitis
0.001 0.828 0.170
M07.1 Arthritis mutilans
0.001 0.828 0.170
M07.0 Distal interphalangeal psoriatic arthropathy
0.001 0.828 0.170
E22.0 Acromegaly and pituitary gigantism
0.000 0.833 0.167
E55.0 Rickets, active
0.000 0.838 0.162
R10.4 Other and unspecified abdominal pain
0.000 0.839 0.161
L43 Lichen planus
0.000 0.845 0.155
E53 Deficiency of other B group vitamins
0.000 0.846 0.154
L44.0 Pityriasis rubra pilaris
0.000 0.846 0.153
L44.9 Papulosquamous disorder, unspecified
0.000 0.847 0.152
L44.8 Other specified papulosquamous disorders
0.000 0.847 0.152
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.847 0.152
L44.3 Lichen ruber moniliformis
0.000 0.847 0.152
L44.2 Lichen striatus
0.000 0.847 0.152
L44.1 Lichen nitidus
0.000 0.847 0.152
L41.9 Parapsoriasis, unspecified
0.000 0.848 0.152
L41.8 Other parapsoriasis
0.000 0.848 0.152
L41.5 Retiform parapsoriasis
0.000 0.848 0.152
L41.4 Large plaque parapsoriasis
0.000 0.848 0.152
L41.3 Small plaque parapsoriasis
0.000 0.848 0.152
L41.2 Lymphomatoid papulosis
0.000 0.848 0.152
L41.1 Pityriasis lichenoides chronica
0.000 0.848 0.152
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.848 0.152
R10.2 Pelvic and perineal pain
0.000 0.854 0.146
M07.69 Other enteropathic arthropathies (Site unspecified)
0.001 0.859 0.140
K74 Fibrosis and cirrhosis of liver
0.000 0.863 0.137
K74.6 Other and unspecified cirrhosis of liver
0.000 0.868 0.132
M07.68 Other enteropathic arthropathies (Other)
0.001 0.869 0.130
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.001 0.869 0.130
M07.66 Other enteropathic arthropathies (Lower leg)
0.001 0.869 0.130
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.001 0.869 0.130
M07.64 Other enteropathic arthropathies (Hand)
0.001 0.869 0.130
M07.63 Other enteropathic arthropathies (Forearm)
0.001 0.869 0.130
M07.62 Other enteropathic arthropathies (Upper arm)
0.001 0.869 0.130
M07.61 Other enteropathic arthropathies (Shoulder region)
0.001 0.869 0.130
M07.60 Other enteropathic arthropathies (Multiple sites)
0.001 0.869 0.130
K74.0 Hepatic fibrosis
0.000 0.870 0.130
K74.3 Primary biliary cirrhosis
0.000 0.873 0.127
E11.3 With ophthalmic complications
0.000 0.875 0.125
E67.8 Other specified hyperalimentation
0.000 0.876 0.123
E67.3 Hypervitaminosis D
0.000 0.876 0.123
E67.2 Megavitamin-B6 syndrome
0.000 0.876 0.123
E67.1 Hypercarotenaemia
0.000 0.876 0.123
E67.0 Hypervitaminosis A
0.000 0.876 0.123
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.001 0.877 0.122
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.001 0.877 0.122
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.001 0.877 0.122
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.001 0.877 0.122
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.001 0.877 0.122
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.001 0.877 0.122
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.001 0.877 0.122
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.001 0.877 0.122
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.001 0.877 0.122
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.001 0.877 0.122
M07.19 Arthritis mutilans (Site unspecified)
0.001 0.877 0.122
M07.18 Arthritis mutilans (Other)
0.001 0.877 0.122
M07.17 Arthritis mutilans (Ankle and foot)
0.001 0.877 0.122
M07.16 Arthritis mutilans (Lower leg)
0.001 0.877 0.122
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.001 0.877 0.122
M07.14 Arthritis mutilans (Hand)
0.001 0.877 0.122
M07.13 Arthritis mutilans (Forearm)
0.001 0.877 0.122
M07.12 Arthritis mutilans (Upper arm)
0.001 0.877 0.122
M07.11 Arthritis mutilans (Shoulder region)
0.001 0.877 0.122
M07.10 Arthritis mutilans (Multiple sites)
0.001 0.877 0.122
M07.29 Psoriatic spondylitis (Site unspecified)
0.001 0.877 0.122
M07.28 Psoriatic spondylitis (Other)
0.001 0.877 0.122
M07.27 Psoriatic spondylitis (Ankle and foot)
0.001 0.877 0.122
M07.26 Psoriatic spondylitis (Lower leg)
0.001 0.877 0.122
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.001 0.877 0.122
M07.24 Psoriatic spondylitis (Hand)
0.001 0.877 0.122
M07.23 Psoriatic spondylitis (Forearm)
0.001 0.877 0.122
M07.22 Psoriatic spondylitis (Upper arm)
0.001 0.877 0.122
M07.21 Psoriatic spondylitis (Shoulder region)
0.001 0.877 0.122
M07.20 Psoriatic spondylitis (Multiple sites)
0.001 0.877 0.122
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.001 0.877 0.122
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.001 0.877 0.122
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.001 0.877 0.122
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.001 0.877 0.122
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.001 0.877 0.122
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.001 0.877 0.122
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.001 0.877 0.122
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.001 0.877 0.122
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.001 0.877 0.122
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.001 0.877 0.122
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.001 0.877 0.122
M07.58 Arthropathy in ulcerative colitis (Other)
0.001 0.877 0.122
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.001 0.877 0.122
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.001 0.877 0.122
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.001 0.877 0.122
M07.54 Arthropathy in ulcerative colitis (Hand)
0.001 0.877 0.122
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.001 0.877 0.122
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.001 0.877 0.122
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.001 0.877 0.122
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.001 0.877 0.122
K70-K77 Diseases of liver
0.000 0.879 0.121
E21.3 Hyperparathyroidism, unspecified
0.000 0.879 0.120
R10.3 Pain localised to other parts of lower abdomen
0.000 0.883 0.117
K72 Hepatic failure, not elsewhere classified
0.000 0.884 0.116
L43.3 Subacute (active) lichen planus
0.000 0.889 0.111
L43.2 Lichenoid drug reaction
0.000 0.889 0.111
L43.1 Bullous lichen planus
0.000 0.889 0.111
L43.0 Hypertrophic lichen planus
0.000 0.889 0.111
E53.1 Pyridoxine deficiency
0.000 0.889 0.110
E53.0 Riboflavin deficiency
0.000 0.889 0.110
K72.9 Hepatic failure, unspecified
0.000 0.890 0.110
E21.0 Primary hyperparathyroidism
0.000 0.892 0.108
K76 Other diseases of liver
0.000 0.896 0.104
K74.5 Biliary cirrhosis, unspecified
0.000 0.897 0.103
K74.1 Hepatic sclerosis
0.000 0.897 0.103
L43.8 Other lichen planus
0.000 0.898 0.102
K76.6 Portal hypertension
0.000 0.900 0.100
K74.4 Secondary biliary cirrhosis
0.000 0.901 0.099
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.901 0.099
K75 Other inflammatory liver diseases
0.000 0.907 0.093
K72.0 Acute and subacute hepatic failure
0.000 0.908 0.092
K71 Toxic liver disease
0.000 0.909 0.091
K72.1 Chronic hepatic failure
0.000 0.911 0.089
K73 Chronic hepatitis, not elsewhere classified
0.000 0.912 0.088
K77 Liver disorders in diseases classified elsewhere
0.000 0.913 0.087
E65 Localised adiposity
0.001 0.918 0.082
K75.4 Autoimmune hepatitis
0.000 0.918 0.082
E04 Other non-toxic goitre
0.041 0.919 0.039
K76.9 Liver disease, unspecified
0.000 0.920 0.080
K75.8 Other specified inflammatory liver diseases
0.000 0.920 0.080
H40.2 Primary angle-closure glaucoma
0.080 0.920 0.000
E53.9 Vitamin B deficiency, unspecified
0.001 0.921 0.079
K76.7 Hepatorenal syndrome
0.000 0.923 0.077
K76.0 Fatty (change of) liver, not elsewhere classified
0.000 0.923 0.077
K76.5 Hepatic veno-occlusive disease
0.000 0.925 0.075
K76.4 Peliosis hepatis
0.000 0.925 0.075
K76.3 Infarction of liver
0.000 0.925 0.075
K76.2 Central haemorrhagic necrosis of liver
0.000 0.925 0.075
K76.1 Chronic passive congestion of liver
0.000 0.927 0.073
L43.9 Lichen planus, unspecified
0.000 0.927 0.072
N04.9 Unspecified
0.000 0.928 0.072
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.930 0.069
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.931 0.069
N04 Nephrotic syndrome
0.000 0.931 0.069
K70 Alcoholic liver disease
0.000 0.932 0.068
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.933 0.067
K75.2 Nonspecific reactive hepatitis
0.000 0.933 0.067
K75.1 Phlebitis of portal vein
0.000 0.933 0.067
K71.9 Toxic liver disease, unspecified
0.000 0.934 0.066
K73.9 Chronic hepatitis, unspecified
0.000 0.934 0.066
N00-N08 Glomerular diseases
0.000 0.934 0.066
K71.8 Toxic liver disease with other disorders of liver
0.000 0.935 0.065
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.935 0.065
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.935 0.065
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.935 0.065
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.935 0.065
K71.2 Toxic liver disease with acute hepatitis
0.000 0.935 0.065
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.935 0.065
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.935 0.065
K71.0 Toxic liver disease with cholestasis
0.000 0.935 0.064
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.936 0.064
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.937 0.063
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.937 0.063
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.937 0.063
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.937 0.063
K70.3 Alcoholic cirrhosis of liver
0.000 0.939 0.061
N05 Unspecified nephritic syndrome
0.000 0.941 0.059
E04.8 Other specified non-toxic goitre
0.030 0.942 0.028
N04.1 Focal and segmental glomerular lesions
0.000 0.942 0.058
N03 Chronic nephritic syndrome
0.000 0.943 0.057
N04.2 Diffuse membranous glomerulonephritis
0.000 0.943 0.056
E28.2 Polycystic ovarian syndrome
0.001 0.946 0.053
K70.1 Alcoholic hepatitis
0.000 0.946 0.054
N05.2 Diffuse membranous glomerulonephritis
0.000 0.947 0.053
K90-K93 Other diseases of the digestive system
0.000 0.947 0.053
K70.0 Alcoholic fatty liver
0.000 0.947 0.052
E04.0 Non-toxic diffuse goitre
0.032 0.948 0.021
E04.2 Non-toxic multinodular goitre
0.052 0.948 0.001
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.949 0.051
E55.9 Vitamin D deficiency, unspecified
0.000 0.949 0.051
N08.5 Glomerular disorders in systemic connective tissue disorders
0.000 0.949 0.051
N04.8 Other
0.000 0.950 0.050
N04.7 Diffuse crescentic glomerulonephritis
0.000 0.950 0.050
N04.6 Dense deposit disease
0.000 0.950 0.050
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.950 0.050
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.950 0.050
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.950 0.050
K75.9 Inflammatory liver disease, unspecified
0.000 0.951 0.049
N03.9 Unspecified
0.000 0.951 0.049
J92.9 Pleural plaque without asbestos
0.000 0.952 0.048
N07 Hereditary nephropathy, not elsewhere classified
0.000 0.953 0.047
N06 Isolated proteinuria with specified morphological lesion
0.000 0.953 0.047
N01 Rapidly progressive nephritic syndrome
0.000 0.953 0.047
N00 Acute nephritic syndrome
0.000 0.953 0.047
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.953 0.047
N08.8 Glomerular disorders in other diseases classified elsewhere
0.000 0.953 0.046
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.000 0.953 0.046
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.000 0.953 0.046
N05.1 Focal and segmental glomerular lesions
0.000 0.954 0.046
E03.9 Hypothyroidism, unspecified
0.000 0.955 0.045
N05.8 Other
0.000 0.955 0.045
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.000 0.956 0.044
N03.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.956 0.044
K70.4 Alcoholic hepatic failure
0.000 0.957 0.043
R22.4 Localised swelling, mass and lump, lower limb
0.043 0.957 0.000
N03.1 Focal and segmental glomerular lesions
0.000 0.957 0.042
E66 Obesity
0.000 0.958 0.042
N05.6 Dense deposit disease
0.000 0.958 0.042

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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