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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3132629
log Bayes Factor = 66.8101
Chromosome 6   position 30,346,093  (GRCh37) Explore rs3132629 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.999 0.001 0.000
E05.9 Thyrotoxicosis, unspecified
0.998 0.002 0.000
E10.3 With ophthalmic complications
0.991 0.009 0.000
E10.2 With renal complications
0.971 0.029 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.949 0.051 0.000
E20-E35 Disorders of other endocrine glands
0.939 0.061 0.000
E14 Unspecified diabetes mellitus
0.936 0.064 0.000
E10.4 With neurological complications
0.917 0.083 0.000
E27 Other disorders of adrenal gland
0.915 0.085 0.000
E16 Other disorders of pancreatic internal secretion
0.913 0.087 0.000
E27.1 Primary adrenocortical insufficiency
0.908 0.092 0.000
E13 Other specified diabetes mellitus
0.867 0.133 0.000
E10.1 With ketoacidosis
0.865 0.135 0.000
E14.3 With ophthalmic complications
0.857 0.143 0.000
E06 Thyroiditis
0.833 0.167 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.831 0.169 0.000
K90 Intestinal malabsorption
0.814 0.186 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.809 0.191 0.000
E16.2 Hypoglycaemia, unspecified
0.801 0.199 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.795 0.205 0.000
E14.8 With unspecified complications
0.791 0.209 0.000
E31 Polyglandular dysfunction
0.782 0.218 0.000
E28 Ovarian dysfunction
0.771 0.229 0.000
E10.8 With unspecified complications
0.771 0.229 0.000
E14.1 With ketoacidosis
0.769 0.231 0.000
E03.8 Other specified hypothyroidism
0.768 0.232 0.000
E50-E64 Other nutritional deficiencies
0.755 0.244 0.000
E14.6 With other specified complications
0.745 0.255 0.000
E14.2 Withrenal complications
0.744 0.256 0.000
E27.2 Addisonian crisis
0.734 0.266 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.730 0.270 0.000
E10.7 With multiple complications
0.729 0.270 0.000
E24 Cushing's syndrome
0.726 0.274 0.000
E22 Hyperfunction of pituitary gland
0.724 0.276 0.000
E13.9 Without complications
0.721 0.279 0.000
E16.1 Other hypoglycaemia
0.721 0.279 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.719 0.281 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.716 0.284 0.000
E05.4 Thyrotoxicosis factitia
0.716 0.284 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.716 0.284 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.709 0.291 0.000
E55 Vitamin D deficiency
0.708 0.292 0.000
E13.3 With ophthalmic complications
0.707 0.293 0.000
E14.4 With neurological complications
0.705 0.295 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.703 0.297 0.000
E06.3 Autoimmune thyroiditis
0.687 0.312 0.000
E28.2 Polycystic ovarian syndrome
0.685 0.315 0.000
E03.1 Congenital hypothyroidism without goitre
0.681 0.319 0.000
E15 Nondiabetic hypoglycaemic coma
0.680 0.320 0.000
E10.6 With other specified complications
0.678 0.322 0.000
E06.5 Other chronic thyroiditis
0.678 0.322 0.000
E55.9 Vitamin D deficiency, unspecified
0.673 0.327 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.673 0.327 0.000
E32 Diseases of thymus
0.673 0.327 0.000
E30 Disorders of puberty, not elsewhere classified
0.673 0.327 0.000
E14.7 With multiple complications
0.671 0.329 0.000
E14.0 With coma
0.671 0.329 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.669 0.331 0.000
E31.0 Autoimmune polyglandular failure
0.669 0.331 0.000
E27.5 Adrenomedullary hyperfunction
0.656 0.344 0.000
E27.0 Other adrenocortical overactivity
0.656 0.344 0.000
K90.8 Other intestinal malabsorption
0.655 0.345 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.654 0.346 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.654 0.346 0.000
E16.4 Abnormal secretion of gastrin
0.654 0.346 0.000
E16.3 Increased secretion of glucagon
0.654 0.346 0.000
K90.9 Intestinal malabsorption, unspecified
0.654 0.346 0.000
E25 Adrenogenital disorders
0.649 0.351 0.000
E05.8 Other thyrotoxicosis
0.643 0.356 0.000
E23 Hypofunction and other disorders of pituitary gland
0.641 0.359 0.000
E20 Hypoparathyroidism
0.637 0.362 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.625 0.375 0.000
E13.8 With unspecified complications
0.622 0.378 0.000
E13.7 With multiple complications
0.622 0.378 0.000
E13.6 With other specified complications
0.622 0.378 0.000
E13.5 With peripheral circulatory complications
0.622 0.378 0.000
E13.4 With neurological complications
0.622 0.378 0.000
E13.2 With renal complications
0.622 0.378 0.000
E13.1 With ketoacidosis
0.622 0.378 0.000
E13.0 With coma
0.622 0.378 0.000
E10.0 With coma
0.621 0.379 0.000
E29 Testicular dysfunction
0.615 0.385 0.000
E14.5 With peripheral circulatory complications
0.615 0.385 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.610 0.390 0.000
E06.1 Subacute thyroiditis
0.609 0.391 0.000
E06.4 Drug-induced thyroiditis
0.597 0.403 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.597 0.403 0.000
E06.0 Acute thyroiditis
0.597 0.403 0.000
E40-E46 Malnutrition
0.596 0.404 0.000
E22.1 Hyperprolactinaemia
0.588 0.412 0.000
E27.9 Disorder of adrenal gland, unspecified
0.585 0.415 0.000
K90.3 Pancreatic steatorrhoea
0.584 0.416 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.584 0.416 0.000
K90.1 Tropical sprue
0.584 0.416 0.000
E10.5 With peripheral circulatory complications
0.581 0.418 0.000
E26 Hyperaldosteronism
0.572 0.428 0.000
E31.9 Polyglandular dysfunction, unspecified
0.560 0.439 0.000
E31.8 Other polyglandular dysfunction
0.560 0.439 0.000
E31.1 Polyglandular hyperfunction
0.560 0.439 0.000
E24.0 Pituitary-dependent Cushing's disease
0.560 0.440 0.000
E58 Dietary calcium deficiency
0.558 0.442 0.000
E28.9 Ovarian dysfunction, unspecified
0.553 0.447 0.000
E28.8 Other ovarian dysfunction
0.553 0.447 0.000
E28.1 Androgen excess
0.553 0.447 0.000
E28.0 Oestrogen excess
0.553 0.447 0.000
E24.2 Drug-induced Cushing's syndrome
0.544 0.456 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.542 0.458 0.000
E63 Other nutritional deficiencies
0.542 0.458 0.000
E50 Vitamin A deficiency
0.542 0.458 0.000
E60 Dietary zinc deficiency
0.542 0.458 0.000
E59 Dietary selenium deficiency
0.542 0.458 0.000
E52 Niacin deficiency [pellagra]
0.542 0.458 0.000
E51 Thiamine deficiency
0.523 0.477 0.000
E24.9 Cushing's syndrome, unspecified
0.522 0.478 0.000
E06.9 Thyroiditis, unspecified
0.521 0.478 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.520 0.480 0.000
E24.3 Ectopic ACTH syndrome
0.520 0.480 0.000
E24.1 Nelson's syndrome
0.520 0.480 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.519 0.480 0.000
E22.8 Other hyperfunction of pituitary gland
0.519 0.480 0.000
E23.2 Diabetes insipidus
0.516 0.484 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E24.8 Other Cushing's syndrome
0.509 0.491 0.000
E54 Ascorbic acid deficiency
0.508 0.492 0.000
E55.0 Rickets, active
0.507 0.493 0.000
E56 Other vitamin deficiencies
0.506 0.494 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.506 0.494 0.000
E07 Other disorders of thyroid
0.488 0.512 0.001
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.513 0.487
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.487 0.513 0.000
E30.9 Disorder of puberty, unspecified
0.483 0.517 0.000
E30.8 Other disorders of puberty
0.483 0.517 0.000
E30.1 Precocious puberty
0.483 0.517 0.000
E30.0 Delayed puberty
0.483 0.517 0.000
E32.9 Disease of thymus, unspecified
0.483 0.517 0.000
E32.8 Other diseases of thymus
0.483 0.517 0.000
E32.1 Abscess of thymus
0.483 0.517 0.000
E32.0 Persistent hyperplasia of thymus
0.483 0.517 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.483 0.517 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.483 0.517 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.483 0.517 0.000
E28.3 Primary ovarian failure
0.468 0.532 0.000
E25.9 Adrenogenital disorder, unspecified
0.466 0.534 0.000
E25.8 Other adrenogenital disorders
0.466 0.534 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.460 0.540 0.000
E23.1 Drug-induced hypopituitarism
0.460 0.540 0.000
E23.0 Hypopituitarism
0.458 0.542 0.000
E20.8 Other hypoparathyroidism
0.457 0.543 0.000
E20.1 Pseudohypoparathyroidism
0.457 0.543 0.000
E20.0 Idiopathic hypoparathyroidism
0.457 0.543 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.442 0.558 0.000
E53 Deficiency of other B group vitamins
0.441 0.559 0.000
E29.8 Other testicular dysfunction
0.441 0.559 0.000
E29.0 Testicular hyperfunction
0.441 0.559 0.000
E23.7 Disorder of pituitary gland, unspecified
0.439 0.561 0.000
E34 Other endocrine disorders
0.438 0.561 0.000
E29.9 Testicular dysfunction, unspecified
0.430 0.569 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.427 0.572 0.000
E45 Retarded development following protein-energy malnutrition
0.427 0.572 0.000
E43 Unspecified severe protein-energy malnutrition
0.427 0.572 0.000
E42 Marasmic kwashiorkor
0.427 0.572 0.000
E41 Nutritional marasmus
0.427 0.572 0.000
E40 Kwashiorkor
0.427 0.572 0.000
E20.9 Hypoparathyroidism, unspecified
0.421 0.578 0.000
E26.8 Other hyperaldosteronism
0.410 0.590 0.000
E26.1 Secondary hyperaldosteronism
0.410 0.590 0.000
E26.9 Hyperaldosteronism, unspecified
0.404 0.596 0.000
E29.1 Testicular hypofunction
0.397 0.603 0.000
E50.9 Vitamin A deficiency, unspecified
0.388 0.611 0.000
E50.8 Other manifestations of vitamin A deficiency
0.388 0.611 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.388 0.611 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.388 0.611 0.000
E50.5 Vitamin A deficiency with night blindness
0.388 0.611 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.388 0.611 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.388 0.611 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.388 0.611 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.388 0.611 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.388 0.611 0.000
E63.9 Nutritional deficiency, unspecified
0.388 0.611 0.000
E63.8 Other specified nutritional deficiencies
0.388 0.611 0.000
E63.1 Imbalance of constituents of food intake
0.388 0.611 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.388 0.611 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.388 0.611 0.000
E64.8 Sequelae of other nutritional deficiencies
0.388 0.611 0.000
E64.3 Sequelae of rickets
0.388 0.611 0.000
E64.2 Sequelae of vitamin C deficiency
0.388 0.611 0.000
E64.1 Sequelae of vitamin A deficiency
0.388 0.611 0.000
E64.0 Sequelae of protein-energy malnutrition
0.388 0.611 0.000
I83 Varicose veins of lower extremities
0.000 0.621 0.379
E51.9 Thiamine deficiency, unspecified
0.375 0.625 0.000
E51.8 Other manifestations of thiamine deficiency
0.375 0.625 0.000
E51.1 Beriberi
0.375 0.625 0.000
E07.8 Other specified disorders of thyroid
0.373 0.627 0.000
E21.2 Other hyperparathyroidism
0.371 0.629 0.000
E27.8 Other specified disorders of adrenal gland
0.370 0.629 0.001
E23.6 Other disorders of pituitary gland
0.366 0.634 0.000
E61 Deficiency of other nutrient elements
0.365 0.635 0.000
E56.9 Vitamin deficiency, unspecified
0.363 0.637 0.000
E56.8 Deficiency of other vitamins
0.363 0.637 0.000
E56.0 Deficiency of vitamin E
0.363 0.637 0.000
E51.2 Wernicke's encephalopathy
0.356 0.644 0.000
E07.1 Dyshormogenetic goitre
0.350 0.650 0.001
E07.0 Hypersecretion of calcitonin
0.350 0.650 0.001
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.650 0.350
E21.4 Other specified disorders of parathyroid gland
0.349 0.651 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.348 0.652 0.000
E56.1 Deficiency of vitamin K
0.328 0.672 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.327 0.673 0.000
E26.0 Primary hyperaldosteronism
0.318 0.681 0.000
E53.1 Pyridoxine deficiency
0.317 0.683 0.000
E53.0 Riboflavin deficiency
0.317 0.683 0.000
E34.5 Androgen resistance syndrome
0.314 0.685 0.000
E34.4 Constitutional tall stature
0.314 0.685 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.314 0.685 0.000
E34.1 Other hypersecretion of intestinal hormones
0.314 0.685 0.000
E22.0 Acromegaly and pituitary gigantism
0.313 0.687 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.689 0.311
E34.8 Other specified endocrine disorders
0.311 0.689 0.000
E34.3 Short stature, not elsewhere classified
0.307 0.693 0.000
E44.1 Mild protein-energy malnutrition
0.306 0.693 0.000
E44.0 Moderate protein-energy malnutrition
0.306 0.693 0.000
E46 Unspecified protein-energy malnutrition
0.307 0.693 0.000
E34.0 Carcinoid syndrome
0.291 0.709 0.000
E53.9 Vitamin B deficiency, unspecified
0.286 0.714 0.000
E21.0 Primary hyperparathyroidism
0.283 0.717 0.000
E21.3 Hyperparathyroidism, unspecified
0.266 0.734 0.000
E61.9 Deficiency of nutrient element, unspecified
0.262 0.738 0.000
E61.8 Deficiency of other specified nutrient elements
0.262 0.738 0.000
E61.7 Deficiency of multiple nutrient elements
0.262 0.738 0.000
E61.6 Vanadium deficiency
0.262 0.738 0.000
E61.5 Molybdenum deficiency
0.262 0.738 0.000
E61.4 Chromium deficiency
0.262 0.738 0.000
E61.3 Manganese deficiency
0.262 0.738 0.000
E61.0 Copper deficiency
0.262 0.738 0.000
E04 Other non-toxic goitre
0.262 0.738 0.000
E53.8 Deficiency of other specified B group vitamins
0.260 0.739 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.746 0.254
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.763 0.237
E61.2 Magnesium deficiency
0.220 0.779 0.000
E65-E68 Obesity and other hyperalimentation
0.216 0.782 0.002
E04.0 Non-toxic diffuse goitre
0.215 0.785 0.000
E04.8 Other specified non-toxic goitre
0.188 0.812 0.000
E04.2 Non-toxic multinodular goitre
0.167 0.833 0.000
E61.1 Iron deficiency
0.165 0.834 0.000
K75.4 Autoimmune hepatitis
0.164 0.836 0.000
E34.9 Endocrine disorder, unspecified
0.161 0.838 0.001
E67 Other hyperalimentation
0.155 0.844 0.001
E68 Sequelae of hyperalimentation
0.155 0.844 0.001
E14.9 Without complications
0.125 0.875 0.000
K75 Other inflammatory liver diseases
0.115 0.885 0.000
E67.8 Other specified hyperalimentation
0.111 0.888 0.001
E67.3 Hypervitaminosis D
0.111 0.888 0.001
E67.2 Megavitamin-B6 syndrome
0.111 0.888 0.001
E67.1 Hypercarotenaemia
0.111 0.888 0.001
E67.0 Hypervitaminosis A
0.111 0.888 0.001
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.102 0.898 0.000
K75.8 Other specified inflammatory liver diseases
0.101 0.899 0.000
K70-K77 Diseases of liver
0.092 0.908 0.000
K72 Hepatic failure, not elsewhere classified
0.085 0.915 0.000
K73 Chronic hepatitis, not elsewhere classified
0.085 0.915 0.000
K72.0 Acute and subacute hepatic failure
0.084 0.916 0.000
K74 Fibrosis and cirrhosis of liver
0.084 0.916 0.000
K75.2 Nonspecific reactive hepatitis
0.083 0.917 0.000
K75.1 Phlebitis of portal vein
0.083 0.917 0.000
K74.5 Biliary cirrhosis, unspecified
0.080 0.920 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.079 0.921 0.000
K73.9 Chronic hepatitis, unspecified
0.076 0.924 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.073 0.927 0.000
K75.0 Abscess of liver
0.068 0.932 0.000
K77 Liver disorders in diseases classified elsewhere
0.066 0.933 0.000
K74.3 Primary biliary cirrhosis
0.066 0.934 0.000
K71 Toxic liver disease
0.065 0.935 0.000
E83 Disorders of mineral metabolism
0.005 0.938 0.057
K74.6 Other and unspecified cirrhosis of liver
0.062 0.938 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.061 0.939 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.061 0.939 0.000
K72.1 Chronic hepatic failure
0.061 0.939 0.000
K74.4 Secondary biliary cirrhosis
0.060 0.940 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.060 0.940 0.000
K74.1 Hepatic sclerosis
0.059 0.941 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.058 0.942 0.000
E04.1 Non-toxic single thyroid nodule
0.053 0.947 0.000
K90-K93 Other diseases of the digestive system
0.052 0.948 0.000
K71.0 Toxic liver disease with cholestasis
0.052 0.948 0.000
E65 Localised adiposity
0.048 0.949 0.003
E07.9 Disorder of thyroid, unspecified
0.048 0.950 0.002
K77.8 Liver disorders in other diseases classified elsewhere
0.048 0.951 0.000
K40 Inguinal hernia
0.000 0.952 0.048
K75.9 Inflammatory liver disease, unspecified
0.048 0.952 0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.048 0.952 0.000
K71.8 Toxic liver disease with other disorders of liver
0.047 0.953 0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.047 0.953 0.000
K71.5 Toxic liver disease with chronic active hepatitis
0.047 0.953 0.000
K71.4 Toxic liver disease with chronic lobular hepatitis
0.047 0.953 0.000
K71.3 Toxic liver disease with chronic persistent hepatitis
0.047 0.953 0.000
K71.2 Toxic liver disease with acute hepatitis
0.047 0.953 0.000
K71.9 Toxic liver disease, unspecified
0.046 0.954 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.003 0.954 0.042
E83.8 Other disorders of mineral metabolism
0.004 0.955 0.041
E83.2 Disorders of zinc metabolism
0.004 0.955 0.041
E83.0 Disorders of copper metabolism
0.004 0.955 0.041
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.044 0.955 0.000
K71.1 Toxic liver disease with hepatic necrosis
0.044 0.955 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.044 0.956 0.000
K74.0 Hepatic fibrosis
0.043 0.957 0.000
M35.0 Sicca syndrome [Sjogren]
0.041 0.959 0.000
E11 Non-insulin-dependent diabetes mellitus
0.039 0.961 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.037 0.962 0.000
K72.9 Hepatic failure, unspecified
0.037 0.963 0.000
K13.0 Diseases of lips
0.000 0.963 0.037
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.965 0.035
E83.3 Disorders of phosphorus metabolism
0.003 0.965 0.032
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.966 0.034
E04.9 Non-toxic goitre, unspecified
0.033 0.967 0.000
E11.6 With other specified complications
0.033 0.967 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.968 0.032
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other
0.032 0.968 0.000
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot
0.032 0.968 0.000
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg
0.032 0.968 0.000
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh
0.032 0.968 0.000
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm
0.032 0.968 0.000
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm
0.032 0.968 0.000
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region
0.032 0.968 0.000
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites
0.032 0.968 0.000
T43.2 Other and unspecified antidepressants
0.000 0.968 0.032
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.969 0.031
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.969 0.031
E11.7 With multiple complications
0.031 0.969 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.970 0.030
I47.2 Ventricular tachycardia
0.030 0.970 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.971 0.029
E11.1 With ketoacidosis
0.028 0.972 0.000
E11.8 With unspecified complications
0.028 0.972 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.972 0.028
T46 Poisoning by agents primarily affecting the cardiovascular system
0.000 0.972 0.027
T43.6 Psychostimulants with abuse potential
0.000 0.973 0.027
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.027 0.973 0.000
K93.1 Megacolon in Chagas' disease
0.027 0.973 0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.027 0.973 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.000 0.973 0.027
E11.2 With renal complications
0.027 0.973 0.000
T39.1 4-Aminophenol derivatives
0.000 0.973 0.027
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec
0.026 0.973 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.000 0.974 0.026
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.974 0.026
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.974 0.025
T43.3 Phenothiazine antipsychotics and neuroleptics
0.000 0.975 0.025
T39.0 Salicylates
0.000 0.975 0.025
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.975 0.025
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.975 0.025
K81.0 Acute cholecystitis
0.000 0.975 0.025
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.000 0.976 0.024
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.000 0.976 0.024
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.000 0.976 0.024
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.977 0.023
T50.8 Diagnostic agents
0.000 0.977 0.023
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.977 0.023
T43.8 Other psychotropic drugs, not elsewhere classified
0.000 0.978 0.022
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.978 0.022
T37.8 Other specified systemic anti-infectives and antiparasitics
0.000 0.978 0.022
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.978 0.022
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.978 0.022
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.978 0.022
T46.5 Other antihypertensive drugs, not elsewhere classified
0.000 0.978 0.021
T43.9 Psychotropic drug, unspecified
0.000 0.979 0.021
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.979 0.021
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.979 0.021
N05.9 Unspecified
0.021 0.979 0.000
T50.4 Drugs affecting uric acid metabolism
0.000 0.979 0.021
T39.4 Antirheumatics, not elsewhere classified
0.000 0.979 0.021
T39.2 Pyrazolone derivatives
0.000 0.979 0.021
T46.1 Calcium-channel blockers
0.000 0.979 0.021
T46.3 Coronary vasodilators, not elsewhere classified
0.000 0.979 0.020
E70-E90 Metabolic disorders
0.020 0.979 0.000
K13 Other diseases of lip and oral mucosa
0.000 0.980 0.020
T50.7 Analeptics and opioid receptor antagonists
0.000 0.980 0.020
T50.5 Appetite depressants
0.000 0.980 0.020
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.980 0.020
T50.1 Loop [high-ceiling] diuretics
0.000 0.980 0.020
T50.0 Mineralocorticoids and their antagonists
0.000 0.980 0.020
N05 Unspecified nephritic syndrome
0.020 0.980 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.000 0.980 0.020
T46.8 Antivaricose drugs, including sclerosing agents
0.000 0.980 0.020
T46.7 Peripheral vasodilators
0.000 0.980 0.020
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.000 0.980 0.020
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.000 0.980 0.020
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.980 0.019
T40.6 Other and unspecified narcotics
0.000 0.980 0.020
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.980 0.019
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.019 0.981 0.000
N05.2 Diffuse membranous glomerulonephritis
0.019 0.981 0.000
K70 Alcoholic liver disease
0.019 0.981 0.000
K13.6 Irritative hyperplasia of oral mucosa
0.000 0.981 0.019
E11.0 With coma
0.018 0.981 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.981 0.019
T42.2 Succinimides and oxazolidinediones
0.000 0.981 0.019
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.000 0.981 0.018
T37.5 Antiviral drugs
0.000 0.981 0.018
T37.4 Anthelminthics
0.000 0.981 0.018
T37.3 Other antiprotozoal drugs
0.000 0.981 0.018
T37.2 Antimalarials and drugs acting on other blood protozoa
0.000 0.981 0.018
T37.1 Antimycobacterial drugs
0.000 0.981 0.018
T37.0 Sulphonamides
0.000 0.981 0.018
N05.8 Other
0.018 0.982 0.000
T40.5 Cocaine
0.000 0.982 0.018
K13.4 Granuloma and granuloma-like lesions of oral mucosa
0.000 0.982 0.018
T36 Poisoning by systemic antibiotics
0.000 0.982 0.018
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.982 0.018
T40.1 Heroin
0.000 0.982 0.018
T42.3 Barbiturates
0.000 0.982 0.018
T48.6 Antiasthmatics, not elsewhere classified
0.000 0.982 0.017
T42.0 Hydantoin derivatives
0.000 0.983 0.017
K76 Other diseases of liver
0.017 0.983 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.983 0.017
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.017 0.983 0.000
E83.4 Disorders of magnesium metabolism
0.003 0.983 0.014
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.000 0.983 0.017
T40.8 Lysergide [LSD]
0.000 0.983 0.017
T40.7 Cannabis (derivatives)
0.000 0.983 0.017
T40.3 Methadone
0.000 0.983 0.017
T40.0 Opium
0.000 0.983 0.017
G20 Parkinson's disease
0.000 0.983 0.017
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.983 0.017
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.000 0.983 0.017
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.000 0.983 0.016
T48.5 Anti-common-cold drugs
0.000 0.983 0.016
T48.4 Expectorants
0.000 0.983 0.016
T48.3 Antitussives
0.000 0.983 0.016
T48.2 Other and unspecified agents primarily acting on muscles
0.000 0.983 0.016
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.000 0.983 0.016
T48.0 Oxytocic drugs
0.000 0.983 0.016
C25.9 Pancreas, unspecified
0.016 0.984 0.000
T49.9 Topical agent, unspecified
0.000 0.984 0.016
T49.8 Other topical agents
0.000 0.984 0.016
T49.7 Dental drugs, topically applied
0.000 0.984 0.016
T49.6 Otorhinolaryngological drugs and preparations
0.000 0.984 0.016
T49.5 Ophthalmological drugs and preparations
0.000 0.984 0.016
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.000 0.984 0.016
T49.3 Emollients, demulcents and protectants
0.000 0.984 0.016
T49.2 Local astringents and local detergents
0.000 0.984 0.016
T49.1 Antipruritics
0.000 0.984 0.016
T40.2 Other opioids
0.000 0.984 0.016
E74 Other disorders of carbohydrate metabolism
0.016 0.984 0.000
E72 Other disorders of amino-acid metabolism
0.016 0.984 0.000
T41.5 Therapeutic gases
0.000 0.984 0.016
T41.4 Anaesthetic, unspecified
0.000 0.984 0.016
T41.3 Local anaesthetics
0.000 0.984 0.016
T41.2 Other and unspecified general anaesthetics
0.000 0.984 0.016
T41.1 Intravenous anaesthetics
0.000 0.984 0.016
T41.0 Inhaled anaesthetics
0.000 0.984 0.016
E73 Lactose intolerance
0.016 0.984 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.000 0.984 0.015
K76.9 Liver disease, unspecified
0.016 0.984 0.000
M72 Fibroblastic disorders
0.015 0.985 0.000
G20-G26 Extrapyramidal and movement disorders
0.000 0.985 0.015
E70 Disorders of aromatic amino-acid metabolism
0.015 0.985 0.000
N05.1 Focal and segmental glomerular lesions
0.015 0.985 0.000
T47.2 Stimulant laxatives
0.000 0.985 0.015
T40.4 Other synthetic narcotics
0.000 0.985 0.015
E77 Disorders of glycoprotein metabolism
0.015 0.985 0.000
E76 Disorders of glycosaminoglycan metabolism
0.015 0.985 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.015 0.985 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.015 0.985 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.000 0.985 0.015
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue
0.000 0.985 0.015
K13.3 Hairy leukoplakia
0.000 0.985 0.015
G24 Dystonia
0.000 0.985 0.015
E11.5 With peripheral circulatory complications
0.015 0.985 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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