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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3134769
log Bayes Factor = 74.3167
Chromosome 6   position 31,205,754  (GRCh37) Explore rs3134769 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E11.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.001 0.999
E16 Other disorders of pancreatic internal secretion
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.002 0.998
E16.2 Hypoglycaemia, unspecified
0.000 0.002 0.998
L40 Psoriasis
0.000 0.002 0.998
E14 Unspecified diabetes mellitus
0.000 0.003 0.997
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.003 0.997
E05.9 Thyrotoxicosis, unspecified
0.000 0.004 0.996
E00-E07 Disorders of thyroid gland
0.000 0.004 0.996
L40.5 Arthropathic psoriasis
0.000 0.007 0.993
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.014 0.986
E70-E90 Metabolic disorders
0.000 0.014 0.986
E78.0 Pure hypercholesterolaemia
0.000 0.016 0.984
E11.0 With coma
0.000 0.019 0.981
E14.9 Without complications
0.000 0.028 0.972
E13 Other specified diabetes mellitus
0.000 0.031 0.969
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.049 0.951
E10.1 With ketoacidosis
0.000 0.051 0.949
E13.9 Without complications
0.000 0.055 0.945
E11.4 With neurological complications
0.000 0.063 0.937
E78.2 Mixed hyperlipidaemia
0.000 0.065 0.935
E10.2 With renal complications
0.000 0.115 0.885
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.115 0.885
E14.3 With ophthalmic complications
0.000 0.116 0.884
E40-E46 Malnutrition
0.000 0.117 0.883
K90 Intestinal malabsorption
0.000 0.123 0.877
E11.1 With ketoacidosis
0.000 0.127 0.873
E11.5 With peripheral circulatory complications
0.000 0.127 0.873
L40.0 Psoriasis vulgaris
0.000 0.141 0.859
E10.8 With unspecified complications
0.000 0.142 0.858
E14.8 With unspecified complications
0.000 0.143 0.857
E10.4 With neurological complications
0.000 0.152 0.848
E14.2 Withrenal complications
0.000 0.167 0.833
L40-L45 Papulosquamous disorders
0.000 0.170 0.830
E16.1 Other hypoglycaemia
0.000 0.174 0.826
E78.5 Hyperlipidaemia, unspecified
0.000 0.196 0.804
E88 Other metabolic disorders
0.000 0.198 0.802
E78.4 Other hyperlipidaemia
0.000 0.200 0.800
E46 Unspecified protein-energy malnutrition
0.000 0.200 0.800
E89.3 Postprocedural hypopituitarism
0.000 0.202 0.798
L43 Lichen planus
0.000 0.203 0.797
E89.2 Postprocedural hypoparathyroidism
0.000 0.204 0.796
E74 Other disorders of carbohydrate metabolism
0.000 0.212 0.788
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.214 0.786
E06 Thyroiditis
0.000 0.218 0.782
E79 Disorders of purine and pyrimidine metabolism
0.000 0.218 0.782
E14.1 With ketoacidosis
0.000 0.226 0.774
L43.9 Lichen planus, unspecified
0.000 0.234 0.766
K90.9 Intestinal malabsorption, unspecified
0.000 0.234 0.766
E14.5 With peripheral circulatory complications
0.000 0.234 0.766
L40.8 Other psoriasis
0.000 0.236 0.764
E10.0 With coma
0.000 0.237 0.763
E14.6 With other specified complications
0.000 0.237 0.763
E85 Amyloidosis
0.000 0.241 0.759
E11.2 With renal complications
0.000 0.246 0.754
E11.6 With other specified complications
0.000 0.262 0.738
E05.8 Other thyrotoxicosis
0.000 0.263 0.737
E10.6 With other specified complications
0.000 0.274 0.726
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.284 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.284 0.716
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.284 0.716
E16.4 Abnormal secretion of gastrin
0.000 0.284 0.716
E16.3 Increased secretion of glucagon
0.000 0.284 0.716
L40.4 Guttate psoriasis
0.000 0.284 0.715
L40.2 Acrodermatitis continua
0.000 0.284 0.715
E14.7 With multiple complications
0.000 0.285 0.715
E14.0 With coma
0.000 0.285 0.715
E05.5 Thyroid crisis or storm
0.000 0.285 0.715
E05.4 Thyrotoxicosis factitia
0.000 0.285 0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.285 0.715
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.285 0.715
E78.8 Other disorders of lipoprotein metabolism
0.000 0.285 0.715
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.286 0.714
E00 Congenital iodine-deficiency syndrome
0.000 0.286 0.714
E13.3 With ophthalmic complications
0.000 0.288 0.712
E78.3 Hyperchylomicronaemia
0.000 0.293 0.707
E77 Disorders of glycoprotein metabolism
0.000 0.293 0.707
E76 Disorders of glycosaminoglycan metabolism
0.000 0.293 0.707
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.293 0.707
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.293 0.707
E72 Other disorders of amino-acid metabolism
0.000 0.305 0.695
E11.8 With unspecified complications
0.000 0.305 0.695
E13.8 With unspecified complications
0.000 0.305 0.695
E13.7 With multiple complications
0.000 0.305 0.695
E13.6 With other specified complications
0.000 0.305 0.695
E13.5 With peripheral circulatory complications
0.000 0.305 0.695
E13.4 With neurological complications
0.000 0.305 0.695
E13.2 With renal complications
0.000 0.305 0.695
E13.1 With ketoacidosis
0.000 0.305 0.695
E13.0 With coma
0.000 0.305 0.695
E78.6 Lipoprotein deficiency
0.000 0.306 0.694
E70 Disorders of aromatic amino-acid metabolism
0.000 0.314 0.686
E06.9 Thyroiditis, unspecified
0.000 0.315 0.685
K90.8 Other intestinal malabsorption
0.000 0.316 0.684
E78.1 Pure hyperglyceridaemia
0.000 0.316 0.684
E10.5 With peripheral circulatory complications
0.000 0.317 0.683
E89.4 Postprocedural ovarian failure
0.000 0.322 0.678
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.322 0.678
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.329 0.670
E14.4 With neurological complications
0.000 0.330 0.670
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.335 0.665
E84 Cystic fibrosis
0.000 0.339 0.661
L40.3 Pustulosis palmaris et plantaris
0.000 0.342 0.658
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.345 0.655
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.346 0.654
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.360 0.640
E88.9 Metabolic disorder, unspecified
0.000 0.361 0.639
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.362 0.638
E50-E64 Other nutritional deficiencies
0.000 0.364 0.636
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.364 0.636
E85.4 Organ-limited amyloidosis
0.000 0.365 0.635
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.365 0.634
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.365 0.634
E89.5 Postprocedural testicular hypofunction
0.000 0.365 0.634
E89.1 Postprocedural hypoinsulinaemia
0.000 0.365 0.634
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.367 0.633
E45 Retarded development following protein-energy malnutrition
0.000 0.367 0.633
E43 Unspecified severe protein-energy malnutrition
0.000 0.367 0.633
E42 Marasmic kwashiorkor
0.000 0.367 0.633
E41 Nutritional marasmus
0.000 0.367 0.633
E40 Kwashiorkor
0.000 0.367 0.633
K90.3 Pancreatic steatorrhoea
0.000 0.371 0.629
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.371 0.629
K90.1 Tropical sprue
0.000 0.371 0.629
L43.8 Other lichen planus
0.000 0.374 0.625
E88.2 Lipomatosis, not elsewhere classified
0.000 0.381 0.619
L44 Other papulosquamous disorders
0.000 0.405 0.595
L41 Parapsoriasis
0.000 0.405 0.595
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.405 0.595
E88.8 Other specified metabolic disorders
0.000 0.409 0.591
E06.5 Other chronic thyroiditis
0.000 0.409 0.591
L42 Pityriasis rosea
0.000 0.410 0.590
L43.3 Subacute (active) lichen planus
0.000 0.428 0.572
L43.2 Lichenoid drug reaction
0.000 0.428 0.572
L43.1 Bullous lichen planus
0.000 0.428 0.572
L43.0 Hypertrophic lichen planus
0.000 0.428 0.572
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.435 0.565
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.435 0.565
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.435 0.565
E74.2 Disorders of galactose metabolism
0.000 0.435 0.565
E74.1 Disorders of fructose metabolism
0.000 0.435 0.565
E65-E68 Obesity and other hyperalimentation
0.000 0.438 0.562
E06.4 Drug-induced thyroiditis
0.000 0.439 0.561
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.439 0.561
E06.1 Subacute thyroiditis
0.000 0.439 0.561
E06.0 Acute thyroiditis
0.000 0.439 0.561
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.439 0.561
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.439 0.561
E79.1 Lesch-Nyhan syndrome
0.000 0.439 0.561
E88.3 Tumour lysis syndrome
0.000 0.441 0.559
E85.9 Amyloidosis, unspecified
0.000 0.446 0.554
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.455 0.544
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.455 0.544
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.455 0.544
E11.3 With ophthalmic complications
0.000 0.461 0.539
E74.0 Glycogen storage disease
0.000 0.470 0.530
E85.8 Other amyloidosis
0.000 0.473 0.527
C83.3 Large cell (diffuse)
0.000 0.478 0.522
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.478 0.522
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E55 Vitamin D deficiency
0.000 0.487 0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.488 0.512
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.488 0.512
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.488 0.512
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.488 0.512
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.488 0.512
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.488 0.512
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.488 0.512
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.488 0.512
E71.3 Disorders of fatty-acid metabolism
0.000 0.493 0.507
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.493 0.507
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.493 0.507
E71.0 Maple-syrup-urine disease
0.000 0.493 0.507
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.493 0.507
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.493 0.507
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.493 0.507
E76.2 Other mucopolysaccharidoses
0.000 0.493 0.507
E76.1 Mucopolysaccharidosis, type II
0.000 0.493 0.507
E76.0 Mucopolysaccharidosis, type I
0.000 0.493 0.507
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.493 0.507
E77.8 Other disorders of glycoprotein metabolism
0.000 0.493 0.507
E77.1 Defects in glycoprotein degradation
0.000 0.493 0.507
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.493 0.507
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.501 0.499
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.501 0.498
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.501 0.498
E72.5 Disorders of glycine metabolism
0.000 0.501 0.498
E72.4 Disorders of ornithine metabolism
0.000 0.501 0.498
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.501 0.498
E72.2 Disorders of urea cycle metabolism
0.000 0.501 0.498
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.501 0.498
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.508 0.492
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.508 0.492
E70.2 Disorders of tyrosine metabolism
0.000 0.508 0.492
E70.1 Other hyperphenylalaninaemias
0.000 0.508 0.492
E70.0 Classical phenylketonuria
0.000 0.508 0.492
E85.3 Secondary systemic amyloidosis
0.000 0.512 0.487
E72.0 Disorders of amino-acid transport
0.000 0.513 0.487
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.513 0.487
E03 Other hypothyroidism
0.117 0.514 0.369
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.515 0.485
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.517 0.483
E84.9 Cystic fibrosis, unspecified
0.000 0.517 0.483
E75.6 Lipid storage disorder, unspecified
0.000 0.519 0.481
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.519 0.481
E75.3 Sphingolipidosis, unspecified
0.000 0.519 0.481
E75.1 Other gangliosidosis
0.000 0.519 0.481
E75.0 GM2 gangliosidosis
0.000 0.519 0.481
E73 Lactose intolerance
0.002 0.523 0.475
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.524 0.476
E84.8 Cystic fibrosis with other manifestations
0.000 0.526 0.474
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.526 0.474
E70.3 Albinism
0.000 0.529 0.471
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.529 0.471
E75.2 Other sphingolipidosis
0.000 0.530 0.470
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.536 0.464
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.536 0.464
E61 Deficiency of other nutrient elements
0.000 0.536 0.464
E51 Thiamine deficiency
0.000 0.538 0.462
E56 Other vitamin deficiencies
0.000 0.539 0.461
E75.5 Other lipid storage disorders
0.000 0.544 0.456
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.544 0.456
E63 Other nutritional deficiencies
0.000 0.544 0.456
E50 Vitamin A deficiency
0.000 0.544 0.456
E60 Dietary zinc deficiency
0.000 0.544 0.456
E59 Dietary selenium deficiency
0.000 0.544 0.456
E52 Niacin deficiency [pellagra]
0.000 0.544 0.456
E44.1 Mild protein-energy malnutrition
0.000 0.546 0.454
E44.0 Moderate protein-energy malnutrition
0.000 0.546 0.454
E54 Ascorbic acid deficiency
0.000 0.553 0.446
E07 Other disorders of thyroid
0.000 0.564 0.436
C85.1 B-cell lymphoma, unspecified
0.000 0.565 0.435
E58 Dietary calcium deficiency
0.000 0.568 0.432
E65 Localised adiposity
0.000 0.571 0.429
L41.9 Parapsoriasis, unspecified
0.000 0.573 0.427
L41.8 Other parapsoriasis
0.000 0.573 0.427
L41.5 Retiform parapsoriasis
0.000 0.573 0.427
L41.4 Large plaque parapsoriasis
0.000 0.573 0.427
L41.3 Small plaque parapsoriasis
0.000 0.573 0.427
L41.2 Lymphomatoid papulosis
0.000 0.573 0.427
L41.1 Pityriasis lichenoides chronica
0.000 0.573 0.427
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.573 0.427
L44.9 Papulosquamous disorder, unspecified
0.000 0.573 0.427
L44.8 Other specified papulosquamous disorders
0.000 0.573 0.427
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.573 0.427
L44.3 Lichen ruber moniliformis
0.000 0.573 0.427
L44.2 Lichen striatus
0.000 0.573 0.427
L44.1 Lichen nitidus
0.000 0.573 0.427
L44.0 Pityriasis rubra pilaris
0.000 0.573 0.427
E55.9 Vitamin D deficiency, unspecified
0.000 0.575 0.425
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.583 0.417
C83.0 Small cell (diffuse)
0.000 0.592 0.408
E67 Other hyperalimentation
0.000 0.597 0.403
E68 Sequelae of hyperalimentation
0.000 0.597 0.403
C82.2 Large cell, follicular
0.000 0.602 0.398
C83.7 Burkitt's tumour
0.000 0.604 0.396
E80.1 Porphyria cutanea tarda
0.000 0.609 0.391
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.617 0.383
E06.3 Autoimmune thyroiditis
0.000 0.618 0.382
C82.0 Small cleaved cell, follicular
0.000 0.618 0.382
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.626 0.374
E80.5 Crigler-Najjar syndrome
0.000 0.626 0.374
E80.3 Defects of catalase and peroxydase
0.000 0.626 0.374
E80.0 Hereditary erythropoietic porphyria
0.000 0.626 0.374
E80.6 Other disorders of bilirubin metabolism
0.000 0.628 0.372
E55.0 Rickets, active
0.000 0.632 0.368
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.634 0.366
C83.1 Small cleaved cell (diffuse)
0.000 0.635 0.365
C83.6 Undifferentiated (diffuse)
0.000 0.642 0.358
C83.4 Immunoblastic (diffuse)
0.000 0.642 0.358
C83.2 Mixed small and large cell (diffuse)
0.000 0.642 0.358
E80.2 Other porphyria
0.000 0.642 0.358
C88 Malignant immunoproliferative diseases
0.000 0.647 0.353
E61.2 Magnesium deficiency
0.000 0.651 0.349
E03.5 Myxoedema coma
0.084 0.651 0.265
E03.4 Atrophy of thyroid (acquired)
0.084 0.651 0.265
E03.3 Postinfectious hypothyroidism
0.084 0.651 0.265
E03.0 Congenital hypothyroidism with diffuse goitre
0.084 0.651 0.265
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.653 0.347
E03.1 Congenital hypothyroidism without goitre
0.079 0.653 0.268
C85.0 Lymphosarcoma
0.000 0.653 0.347
E73.8 Other lactose intolerance
0.001 0.658 0.341
E73.1 Secondary lactase deficiency
0.001 0.658 0.341
E73.0 Congenital lactase deficiency
0.001 0.658 0.341
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.659 0.341
C82.4 Follicular lymphoma grade IIIb
0.000 0.659 0.341
E03.9 Hypothyroidism, unspecified
0.341 0.659 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.073 0.661 0.266
E51.2 Wernicke's encephalopathy
0.000 0.662 0.338
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.662 0.338
C82.6 Cutaneous follicle centre lymphoma
0.000 0.662 0.337
C82.5 Diffuse follicle centre lymphoma
0.000 0.662 0.337
E56.1 Deficiency of vitamin K
0.000 0.664 0.336
E61.9 Deficiency of nutrient element, unspecified
0.000 0.667 0.333
E61.8 Deficiency of other specified nutrient elements
0.000 0.667 0.333
E61.7 Deficiency of multiple nutrient elements
0.000 0.667 0.333
E61.6 Vanadium deficiency
0.000 0.667 0.333
E61.5 Molybdenum deficiency
0.000 0.667 0.333
E61.4 Chromium deficiency
0.000 0.667 0.333
E61.3 Manganese deficiency
0.000 0.667 0.333
E61.0 Copper deficiency
0.000 0.667 0.333
E51.9 Thiamine deficiency, unspecified
0.000 0.668 0.331
E51.8 Other manifestations of thiamine deficiency
0.000 0.668 0.331
E51.1 Beriberi
0.000 0.668 0.331
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.669 0.331
E56.9 Vitamin deficiency, unspecified
0.000 0.669 0.331
E56.8 Deficiency of other vitamins
0.000 0.669 0.331
E56.0 Deficiency of vitamin E
0.000 0.669 0.331
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.672 0.328
E50.9 Vitamin A deficiency, unspecified
0.000 0.673 0.327
E50.8 Other manifestations of vitamin A deficiency
0.000 0.673 0.327
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.673 0.327
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.673 0.327
E50.5 Vitamin A deficiency with night blindness
0.000 0.673 0.327
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.673 0.327
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.673 0.327
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.673 0.327
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.673 0.327
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.673 0.327
E63.9 Nutritional deficiency, unspecified
0.000 0.673 0.327
E63.8 Other specified nutritional deficiencies
0.000 0.673 0.327
E63.1 Imbalance of constituents of food intake
0.000 0.673 0.327
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.673 0.327
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.673 0.327
E64.8 Sequelae of other nutritional deficiencies
0.000 0.673 0.327
E64.3 Sequelae of rickets
0.000 0.673 0.327
E64.2 Sequelae of vitamin C deficiency
0.000 0.673 0.327
E64.1 Sequelae of vitamin A deficiency
0.000 0.673 0.327
E64.0 Sequelae of protein-energy malnutrition
0.000 0.673 0.327
E61.1 Iron deficiency
0.000 0.677 0.323
C86 Other specified types of T/NK-cell lymphoma
0.000 0.680 0.320
E07.1 Dyshormogenetic goitre
0.000 0.687 0.313
E07.0 Hypersecretion of calcitonin
0.000 0.687 0.313
C94 Other leukaemias of specified cell type
0.000 0.689 0.310
C93 Monocytic leukaemia
0.000 0.691 0.308
E86 Volume depletion
0.000 0.698 0.302
E03.8 Other specified hypothyroidism
0.079 0.701 0.220
C83.5 Lymphoblastic (diffuse)
0.000 0.702 0.297
E67.8 Other specified hyperalimentation
0.000 0.711 0.289
E67.3 Hypervitaminosis D
0.000 0.711 0.289
E67.2 Megavitamin-B6 syndrome
0.000 0.711 0.289
E67.1 Hypercarotenaemia
0.000 0.711 0.289
E67.0 Hypervitaminosis A
0.000 0.711 0.289
E07.8 Other specified disorders of thyroid
0.000 0.716 0.283
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.717 0.283
C95 Leukaemia of unspecified cell type
0.000 0.717 0.283
E53 Deficiency of other B group vitamins
0.000 0.724 0.276
C84.0 Mycosis fungoides
0.000 0.728 0.272
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.732 0.268
C81 Hodgkin's disease
0.000 0.741 0.259
C88.9 Malignant immunoproliferative disease, unspecified
0.000 0.746 0.253
C88.7 Other malignant immunoproliferative diseases
0.000 0.746 0.253
C88.3 Immunoproliferative small intestinal disease
0.000 0.746 0.253
C88.2 Gamma heavy chain disease
0.000 0.746 0.253
C88.1 Alpha heavy chain disease
0.000 0.746 0.253
Z86.1 Personal history of infectious and parasitic diseases
0.000 0.750 0.250
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.751 0.249
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.751 0.249
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.751 0.249
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.751 0.249
C84.3 Lymphoepithelioid lymphoma
0.000 0.751 0.249
C84.2 T-zone lymphoma
0.000 0.751 0.249
C84.1 Sezary's diease
0.000 0.751 0.249
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.755 0.245
C96.8 Histiocytic sarcoma
0.000 0.755 0.245
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.755 0.245
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.755 0.245
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.755 0.245
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.755 0.245
C96.3 True histiocytic lymphoma
0.000 0.755 0.245
C96.2 Malignant mast cell tumour
0.000 0.755 0.245
C96.1 Malignant histiocytosis
0.000 0.755 0.245
C96.0 Letterer-Siwe disease
0.000 0.755 0.245
C82.3 Follicular lymphoma grade IIIa
0.000 0.760 0.239
C84.4 Peripheral T-cell lymphoma
0.000 0.761 0.239
C84.5 Other and unspecified T-cell lymphomas
0.000 0.762 0.238
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.771 0.229
C86.4 Blastic NK-cell lymphoma
0.000 0.771 0.229
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.771 0.229
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.771 0.229
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.771 0.229
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.771 0.229
C88.0 Waldenstrom's macroglobulinaemia
0.000 0.772 0.228
C94.7 Other specified leukaemias
0.000 0.777 0.223
C94.5 Acute myelofibrosis
0.000 0.777 0.223
C94.4 Acute panmyelosis
0.000 0.777 0.223
C94.3 Mast cell leukaemia
0.000 0.777 0.223
C94.2 Acute megakaryoblastic leukaemia
0.000 0.777 0.223
C94.1 Chronic erythraemia
0.000 0.777 0.223
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.777 0.223
C93.9 Monocytic leukaemia, unspecified
0.000 0.779 0.221
C93.7 Other monocytic leukaemia
0.000 0.779 0.221
C93.3 Juvenile myelomonocytic leukaemia
0.000 0.779 0.221
C93.2 Subacute monocytic leukaemia
0.000 0.779 0.221
C93.0 Acute monocytic leukaemia
0.000 0.779 0.221
H54 Blindness and low vision
0.000 0.781 0.219
H54.7 Unspecified visual loss
0.000 0.783 0.217
H54.9 Unspecified visual impairment (binocular)
0.000 0.789 0.211
C95.1 Chronic leukaemia of unspecified cell type
0.000 0.789 0.211
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.792 0.208
H54.0 Blindness, both eyes
0.000 0.793 0.206
C95.7 Other leukaemia of unspecified cell type
0.000 0.797 0.203
C95.2 Subacute leukaemia of unspecified cell type
0.000 0.797 0.203
E53.1 Pyridoxine deficiency
0.000 0.802 0.198
E53.0 Riboflavin deficiency
0.000 0.802 0.198
C81.0 Lymphocytic predominance
0.000 0.807 0.193
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.000 0.808 0.192
C81.9 Hodgkin's disease, unspecified
0.000 0.810 0.190
H54.4 Blindness, one eye
0.000 0.810 0.190
E80.4 Gilbert's syndrome
0.000 0.811 0.189
C93.1 Chronic monocytic leukaemia
0.000 0.811 0.188
E66 Obesity
0.000 0.813 0.187
C81.7 Other Hodgkin's disease
0.000 0.814 0.186
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.814 0.186
C81.3 Lymphocytic depletion
0.000 0.814 0.186
E53.9 Vitamin B deficiency, unspecified
0.000 0.817 0.183
C95.9 Leukaemia, unspecified
0.000 0.821 0.179
K90-K93 Other diseases of the digestive system
0.000 0.824 0.176
E20-E35 Disorders of other endocrine glands
0.000 0.829 0.171
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.834 0.166
C95.0 Acute leukaemia of unspecified cell type
0.000 0.835 0.165
H53-H54 Visual disturbances and blindness
0.000 0.835 0.165
C81.2 Mixed cellularity
0.000 0.836 0.163
E89.0 Postprocedural hypothyroidism
0.000 0.839 0.161
H54.6 Unqualified visual loss, one eye
0.000 0.842 0.158
H54.3 Unqualified visual loss, both eyes
0.000 0.842 0.157
H54.2 Low vision, both eyes
0.000 0.843 0.156
H53.8 Other visual disturbances
0.000 0.846 0.154
H53 Visual disturbances
0.000 0.846 0.154
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.847 0.153
H54.5 Low vision, one eye
0.000 0.859 0.141
E66.1 Drug-induced obesity
0.000 0.866 0.134
H54.1 Blindness, one eye, low vision, other eye
0.000 0.867 0.133
E22 Hyperfunction of pituitary gland
0.000 0.868 0.132
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.868 0.132
E25 Adrenogenital disorders
0.000 0.868 0.132
H53.2 Diplopia
0.000 0.869 0.131
E24 Cushing's syndrome
0.000 0.871 0.129
E66.0 Obesity due to excess calories
0.000 0.872 0.128
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.873 0.127
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.874 0.126
C91 Lymphoid leukaemia
0.000 0.874 0.126
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.877 0.123
E32 Diseases of thymus
0.000 0.877 0.123
E30 Disorders of puberty, not elsewhere classified
0.000 0.877 0.123
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.879 0.121
H53.1 Subjective visual disturbances
0.000 0.883 0.117
C81.1 Nodular sclerosis
0.000 0.883 0.116
E31 Polyglandular dysfunction
0.000 0.887 0.113
E73.9 Lactose intolerance, unspecified
0.004 0.888 0.109
C90.1 Plasma cell leukaemia
0.000 0.888 0.112
E07.9 Disorder of thyroid, unspecified
0.000 0.888 0.112
E24.0 Pituitary-dependent Cushing's disease
0.000 0.888 0.112
H53.6 Night blindness
0.000 0.889 0.111
H53.5 Colour vision deficiencies
0.000 0.889 0.111
C92 Myeloid leukaemia
0.000 0.889 0.110
E23 Hypofunction and other disorders of pituitary gland
0.000 0.891 0.109
E22.1 Hyperprolactinaemia
0.000 0.892 0.108
E34 Other endocrine disorders
0.000 0.892 0.108
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.892 0.108
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.000 0.893 0.107
E26 Hyperaldosteronism
0.000 0.895 0.105
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.896 0.104
E22.0 Acromegaly and pituitary gigantism
0.000 0.896 0.104
C91.9 Lymphoid leukaemia, unspecified
0.000 0.898 0.102
K91.1 Postgastric surgery syndromes
0.000 0.899 0.101
H53.3 Other disorders of binocular vision
0.000 0.900 0.100
E20 Hypoparathyroidism
0.000 0.901 0.099
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.901 0.099
K91.5 Postcholecystectomy syndrome
0.000 0.902 0.098
E04 Other non-toxic goitre
0.000 0.902 0.098
J33.9 Nasal polyp, unspecified
0.000 0.904 0.096
C90.3 Solitary plasmacytoma
0.000 0.904 0.096
E28 Ovarian dysfunction
0.000 0.905 0.095
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.905 0.095
E22.8 Other hyperfunction of pituitary gland
0.000 0.905 0.095
E25.9 Adrenogenital disorder, unspecified
0.000 0.905 0.095
E25.8 Other adrenogenital disorders
0.000 0.905 0.095
H53.0 Amblyopia ex anopsia
0.000 0.906 0.094

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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