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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3134798
log Bayes Factor = 127.482
Chromosome 6   position 32,184,705  (GRCh37) Explore rs3134798 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.003 0.997
I10 Essential (primary) hypertension
0.000 0.004 0.996
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.005 0.995
E14 Unspecified diabetes mellitus
0.000 0.007 0.993
E10.4 With neurological complications
0.000 0.007 0.993
E16 Other disorders of pancreatic internal secretion
0.000 0.009 0.991
K51 Ulcerative colitis
0.989 0.011 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.019 0.981
E14.3 With ophthalmic complications
0.000 0.021 0.979
K51.3 Ulcerative (chronic) rectosigmoiditis
0.978 0.022 0.000
E83.1 Disorders of iron metabolism
0.978 0.022 0.000
E11.1 With ketoacidosis
0.000 0.036 0.964
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.050 0.950
E11.3 With ophthalmic complications
0.000 0.059 0.941
G35-G37 Demyelinating diseases of the central nervous system
0.939 0.061 0.000
E10.5 With peripheral circulatory complications
0.000 0.063 0.937
G37 Other demyelinating diseases of central nervous system
0.926 0.074 0.000
E13 Other specified diabetes mellitus
0.000 0.096 0.904
G37.9 Demyelinating disease of central nervous system, unspecified
0.899 0.101 0.000
K51.8 Other ulcerative colitis
0.891 0.109 0.000
E10.8 With unspecified complications
0.000 0.112 0.888
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.122 0.878
E10.0 With coma
0.000 0.123 0.877
K51.5 Mucosal proctocolitis
0.873 0.127 0.000
E11.2 With renal complications
0.000 0.138 0.862
E03.8 Other specified hypothyroidism
0.000 0.148 0.852
E14.8 With unspecified complications
0.000 0.149 0.851
E11.5 With peripheral circulatory complications
0.000 0.159 0.841
E13.9 Without complications
0.000 0.160 0.840
E07 Other disorders of thyroid
0.000 0.173 0.827
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.182 0.818
E10.2 With renal complications
0.000 0.190 0.810
K51.4 Pseudopolyposis of colon
0.800 0.200 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.797 0.203 0.000
E16.1 Other hypoglycaemia
0.000 0.206 0.794
E14.4 With neurological complications
0.000 0.219 0.781
I10-I15 Hypertensive diseases
0.000 0.222 0.778
Z93.2 Ileostomy status
0.778 0.222 0.000
E11.6 With other specified complications
0.000 0.242 0.758
E14.9 Without complications
0.000 0.247 0.753
E40-E46 Malnutrition
0.000 0.248 0.752
E10.6 With other specified complications
0.000 0.250 0.750
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.731 0.269 0.000
E11.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
E10.7 With multiple complications
0.000 0.286 0.714
E03.1 Congenital hypothyroidism without goitre
0.000 0.287 0.713
E15 Nondiabetic hypoglycaemic coma
0.000 0.287 0.713
E14.7 With multiple complications
0.000 0.288 0.712
E14.1 With ketoacidosis
0.000 0.288 0.712
E14.0 With coma
0.000 0.288 0.712
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.290 0.710
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.290 0.710
E16.4 Abnormal secretion of gastrin
0.000 0.290 0.710
E16.3 Increased secretion of glucagon
0.000 0.290 0.710
I12 Hypertensive renal disease
0.000 0.294 0.706
G36 Other acute disseminated demyelination
0.705 0.295 0.000
E14.6 With other specified complications
0.000 0.296 0.704
L40.9 Psoriasis, unspecified
0.000 0.299 0.701
E14.2 Withrenal complications
0.000 0.299 0.700
E14.5 With peripheral circulatory complications
0.000 0.300 0.700
I15 Secondary hypertension
0.000 0.303 0.697
E07.9 Disorder of thyroid, unspecified
0.000 0.307 0.693
L40 Psoriasis
0.000 0.308 0.692
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.316 0.684
E11.0 With coma
0.000 0.317 0.683
L40.5 Arthropathic psoriasis
0.000 0.320 0.680
K51.2 Ulcerative (chronic) proctitis
0.676 0.324 0.000
G37.5 Concentric sclerosis [Balo]
0.664 0.336 0.000
G37.4 Subacute necrotising myelitis
0.664 0.336 0.000
G37.2 Central pontine myelinolysis
0.664 0.336 0.000
G37.1 Central demyelination of corpus callosum
0.664 0.336 0.000
G37.0 Diffuse sclerosis
0.664 0.336 0.000
D64.9 Anaemia, unspecified
0.000 0.338 0.662
E13.8 With unspecified complications
0.000 0.351 0.648
E13.7 With multiple complications
0.000 0.351 0.648
E13.6 With other specified complications
0.000 0.351 0.648
E13.5 With peripheral circulatory complications
0.000 0.351 0.648
E13.4 With neurological complications
0.000 0.351 0.648
E13.2 With renal complications
0.000 0.351 0.648
E13.1 With ketoacidosis
0.000 0.351 0.648
E13.0 With coma
0.000 0.351 0.648
I12.9 Hypertensive renal disease without renal failure
0.000 0.363 0.637
E13.3 With ophthalmic complications
0.000 0.367 0.633
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.368 0.632
K51.0 Ulcerative (chronic) enterocolitis
0.622 0.378 0.000
E06 Thyroiditis
0.000 0.384 0.616
E05.8 Other thyrotoxicosis
0.000 0.390 0.610
E07.8 Other specified disorders of thyroid
0.000 0.391 0.609
L40.0 Psoriasis vulgaris
0.000 0.401 0.599
E83 Disorders of mineral metabolism
0.593 0.401 0.006
E11.8 With unspecified complications
0.000 0.404 0.596
I15.9 Seconday hypertension, unspecified
0.000 0.405 0.595
E07.1 Dyshormogenetic goitre
0.000 0.407 0.593
E07.0 Hypersecretion of calcitonin
0.000 0.407 0.593
K51.1 Ulcerative (chronic) ileocolitis
0.588 0.412 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.423 0.577
E46 Unspecified protein-energy malnutrition
0.000 0.426 0.574
E83.3 Disorders of phosphorus metabolism
0.568 0.431 0.001
I15.1 Hypertension secondary to other renal disorders
0.000 0.433 0.567
I12.0 Hypertensive renal disease with renal failure
0.000 0.445 0.555
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.461 0.539
E45 Retarded development following protein-energy malnutrition
0.000 0.461 0.539
E43 Unspecified severe protein-energy malnutrition
0.000 0.461 0.539
E42 Marasmic kwashiorkor
0.000 0.461 0.539
E41 Nutritional marasmus
0.000 0.461 0.539
E40 Kwashiorkor
0.000 0.461 0.539
G36.0 Neuromyelitis optica [Devic]
0.537 0.463 0.000
L40.8 Other psoriasis
0.000 0.467 0.533
I15.0 Renovascular hypertension
0.000 0.472 0.528
L40.3 Pustulosis palmaris et plantaris
0.000 0.475 0.525
I13 Hypertensive heart and renal disease
0.000 0.478 0.522
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.481 0.519
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
G36.9 Acute disseminated demyelination, unspecified
0.506 0.494 0.000
G36.8 Other specified acute disseminated demyelination
0.506 0.494 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.506 0.494 0.000
I15.8 Other secondary hypertension
0.000 0.500 0.500
I15.2 Hypertension secondary to endocrine disorders
0.000 0.500 0.500
L40.4 Guttate psoriasis
0.000 0.504 0.496
L40.2 Acrodermatitis continua
0.000 0.504 0.496
L40.1 Generalised pustular psoriasis
0.000 0.504 0.496
E28 Ovarian dysfunction
0.000 0.513 0.487
E23 Hypofunction and other disorders of pituitary gland
0.000 0.513 0.487
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.528 0.472
I11 Hypertensive heart disease
0.000 0.540 0.460
E83.9 Disorder of mineral metabolism, unspecified
0.451 0.545 0.004
K90 Intestinal malabsorption
0.000 0.547 0.453
E23.2 Diabetes insipidus
0.000 0.554 0.446
E06.5 Other chronic thyroiditis
0.000 0.558 0.442
E06.4 Drug-induced thyroiditis
0.000 0.558 0.442
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.558 0.442
E06.1 Subacute thyroiditis
0.000 0.558 0.442
E06.0 Acute thyroiditis
0.000 0.558 0.442
E21.3 Hyperparathyroidism, unspecified
0.000 0.565 0.435
E29 Testicular dysfunction
0.000 0.568 0.432
E83.8 Other disorders of mineral metabolism
0.425 0.570 0.004
E83.2 Disorders of zinc metabolism
0.425 0.570 0.004
E83.0 Disorders of copper metabolism
0.425 0.570 0.004
E28.2 Polycystic ovarian syndrome
0.000 0.577 0.423
E11.4 With neurological complications
0.000 0.579 0.421
E06.3 Autoimmune thyroiditis
0.000 0.581 0.419
E65-E68 Obesity and other hyperalimentation
0.000 0.584 0.416
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.586 0.413
E32 Diseases of thymus
0.000 0.586 0.413
E30 Disorders of puberty, not elsewhere classified
0.000 0.586 0.413
E25 Adrenogenital disorders
0.000 0.588 0.412
E26 Hyperaldosteronism
0.000 0.597 0.403
E31 Polyglandular dysfunction
0.000 0.605 0.395
K90.9 Intestinal malabsorption, unspecified
0.000 0.610 0.390
E44.1 Mild protein-energy malnutrition
0.000 0.613 0.386
E44.0 Moderate protein-energy malnutrition
0.000 0.613 0.386
E24 Cushing's syndrome
0.000 0.616 0.384
E23.6 Other disorders of pituitary gland
0.000 0.619 0.381
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.625 0.374
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.625 0.374
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.625 0.374
E23.7 Disorder of pituitary gland, unspecified
0.000 0.626 0.374
E06.9 Thyroiditis, unspecified
0.000 0.628 0.372
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.633 0.367
E22 Hyperfunction of pituitary gland
0.000 0.639 0.361
L40-L45 Papulosquamous disorders
0.000 0.641 0.359
E28.3 Primary ovarian failure
0.000 0.649 0.351
E28.9 Ovarian dysfunction, unspecified
0.000 0.650 0.349
E28.8 Other ovarian dysfunction
0.000 0.650 0.349
E28.1 Androgen excess
0.000 0.650 0.349
E28.0 Oestrogen excess
0.000 0.650 0.349
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.651 0.349
E23.1 Drug-induced hypopituitarism
0.000 0.651 0.349
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.655 0.345
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.661 0.339
E21.4 Other specified disorders of parathyroid gland
0.000 0.661 0.339
E20 Hypoparathyroidism
0.000 0.663 0.337
E83.4 Disorders of magnesium metabolism
0.333 0.665 0.002
E21.2 Other hyperparathyroidism
0.000 0.669 0.331
E29.1 Testicular hypofunction
0.000 0.671 0.329
H36.0 Diabetic retinopathy
0.000 0.675 0.325
K90.3 Pancreatic steatorrhoea
0.000 0.675 0.325
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.675 0.325
K90.1 Tropical sprue
0.000 0.675 0.325
K90.8 Other intestinal malabsorption
0.000 0.683 0.317
E29.9 Testicular dysfunction, unspecified
0.000 0.690 0.310
E29.8 Other testicular dysfunction
0.000 0.690 0.310
E29.0 Testicular hyperfunction
0.000 0.690 0.310
E24.0 Pituitary-dependent Cushing's disease
0.000 0.692 0.308
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.694 0.306
L43 Lichen planus
0.000 0.698 0.302
E22.1 Hyperprolactinaemia
0.000 0.701 0.299
E67 Other hyperalimentation
0.000 0.702 0.298
E68 Sequelae of hyperalimentation
0.000 0.702 0.298
E30.9 Disorder of puberty, unspecified
0.000 0.703 0.297
E30.8 Other disorders of puberty
0.000 0.703 0.297
E30.1 Precocious puberty
0.000 0.703 0.297
E30.0 Delayed puberty
0.000 0.703 0.297
E32.9 Disease of thymus, unspecified
0.000 0.703 0.297
E32.8 Other diseases of thymus
0.000 0.703 0.297
E32.1 Abscess of thymus
0.000 0.703 0.297
E32.0 Persistent hyperplasia of thymus
0.000 0.703 0.297
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.703 0.297
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.703 0.297
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.703 0.297
E25.9 Adrenogenital disorder, unspecified
0.000 0.704 0.295
E25.8 Other adrenogenital disorders
0.000 0.704 0.295
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.706 0.294
E26.9 Hyperaldosteronism, unspecified
0.000 0.711 0.289
E26.8 Other hyperaldosteronism
0.000 0.711 0.289
E26.1 Secondary hyperaldosteronism
0.000 0.711 0.289
D64 Other anaemias
0.001 0.716 0.284
E31.9 Polyglandular dysfunction, unspecified
0.000 0.716 0.283
E31.8 Other polyglandular dysfunction
0.000 0.716 0.283
E31.1 Polyglandular hyperfunction
0.000 0.716 0.283
E26.0 Primary hyperaldosteronism
0.000 0.721 0.279
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.724 0.275
E24.3 Ectopic ACTH syndrome
0.000 0.724 0.275
E24.2 Drug-induced Cushing's syndrome
0.000 0.724 0.275
E24.1 Nelson's syndrome
0.000 0.724 0.275
L43.9 Lichen planus, unspecified
0.000 0.727 0.273
E34 Other endocrine disorders
0.000 0.728 0.271
M45.X9 Ankylosing spondylitis (Site unspecified)
0.271 0.729 0.000
E78.0 Pure hypercholesterolaemia
0.000 0.732 0.268
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.733 0.267
E31.0 Autoimmune polyglandular failure
0.000 0.734 0.265
E65 Localised adiposity
0.000 0.740 0.260
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.741 0.259
E22.8 Other hyperfunction of pituitary gland
0.000 0.741 0.259
E50-E64 Other nutritional deficiencies
0.000 0.742 0.258
L44 Other papulosquamous disorders
0.000 0.742 0.257
L41 Parapsoriasis
0.000 0.742 0.257
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.742 0.257
E70-E90 Metabolic disorders
0.012 0.747 0.241
E24.9 Cushing's syndrome, unspecified
0.000 0.750 0.250
E20.8 Other hypoparathyroidism
0.000 0.758 0.242
E20.1 Pseudohypoparathyroidism
0.000 0.758 0.242
E20.0 Idiopathic hypoparathyroidism
0.000 0.758 0.242
L42 Pityriasis rosea
0.000 0.762 0.238
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.001 0.763 0.236
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.766 0.233
E27 Other disorders of adrenal gland
0.001 0.771 0.228
E24.8 Other Cushing's syndrome
0.000 0.774 0.226
M45 Ankylosing spondylitis
0.223 0.777 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.780 0.220
L43.3 Subacute (active) lichen planus
0.000 0.783 0.217
L43.2 Lichenoid drug reaction
0.000 0.783 0.217
L43.1 Bullous lichen planus
0.000 0.783 0.217
L43.0 Hypertrophic lichen planus
0.000 0.783 0.217
E67.8 Other specified hyperalimentation
0.000 0.786 0.214
E67.3 Hypervitaminosis D
0.000 0.786 0.214
E67.2 Megavitamin-B6 syndrome
0.000 0.786 0.214
E67.1 Hypercarotenaemia
0.000 0.786 0.214
E67.0 Hypervitaminosis A
0.000 0.786 0.214
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.208 0.792 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.001 0.792 0.206
D64.4 Congenital dyserythropoietic anaemia
0.001 0.796 0.203
D64.3 Other sideroblastic anaemias
0.001 0.796 0.203
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.001 0.796 0.203
D64.1 Secondary sideroblastic anaemia due to disease
0.001 0.796 0.203
D64.0 Hereditary sideroblastic anaemia
0.001 0.796 0.203
E74 Other disorders of carbohydrate metabolism
0.007 0.798 0.195
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.804 0.196
E34.5 Androgen resistance syndrome
0.000 0.805 0.195
E34.4 Constitutional tall stature
0.000 0.805 0.195
E34.3 Short stature, not elsewhere classified
0.000 0.805 0.195
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.805 0.195
E34.1 Other hypersecretion of intestinal hormones
0.000 0.805 0.195
E27.9 Disorder of adrenal gland, unspecified
0.000 0.806 0.194
E78.1 Pure hyperglyceridaemia
0.001 0.808 0.191
E34.8 Other specified endocrine disorders
0.000 0.812 0.188
E51 Thiamine deficiency
0.000 0.814 0.185
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.815 0.185
E63 Other nutritional deficiencies
0.000 0.815 0.185
E50 Vitamin A deficiency
0.000 0.815 0.185
E60 Dietary zinc deficiency
0.000 0.815 0.185
E59 Dietary selenium deficiency
0.000 0.815 0.185
E54 Ascorbic acid deficiency
0.000 0.815 0.185
E52 Niacin deficiency [pellagra]
0.000 0.815 0.185
L41.9 Parapsoriasis, unspecified
0.000 0.815 0.185
L41.8 Other parapsoriasis
0.000 0.815 0.185
L41.5 Retiform parapsoriasis
0.000 0.815 0.185
L41.4 Large plaque parapsoriasis
0.000 0.815 0.185
L41.3 Small plaque parapsoriasis
0.000 0.815 0.185
L41.2 Lymphomatoid papulosis
0.000 0.815 0.185
L41.1 Pityriasis lichenoides chronica
0.000 0.815 0.185
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.815 0.185
L44.9 Papulosquamous disorder, unspecified
0.000 0.815 0.185
L44.8 Other specified papulosquamous disorders
0.000 0.815 0.185
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.815 0.185
L44.3 Lichen ruber moniliformis
0.000 0.815 0.185
L44.2 Lichen striatus
0.000 0.815 0.185
L44.1 Lichen nitidus
0.000 0.815 0.185
L44.0 Pityriasis rubra pilaris
0.000 0.815 0.185
L43.8 Other lichen planus
0.000 0.815 0.185
E78.2 Mixed hyperlipidaemia
0.001 0.816 0.183
N18.9 Chronic renal failure, unspecified
0.000 0.817 0.183
E77 Disorders of glycoprotein metabolism
0.009 0.819 0.173
E76 Disorders of glycosaminoglycan metabolism
0.009 0.819 0.173
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.009 0.819 0.173
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.009 0.819 0.173
E70 Disorders of aromatic amino-acid metabolism
0.009 0.819 0.173
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.009 0.819 0.173
E58 Dietary calcium deficiency
0.000 0.823 0.177
H36 Retinal disorders in diseases classified elsewhere
0.000 0.825 0.175
N18 Chronic renal failure
0.000 0.826 0.174
E56 Other vitamin deficiencies
0.001 0.828 0.172
E78.6 Lipoprotein deficiency
0.001 0.828 0.171
E72 Other disorders of amino-acid metabolism
0.009 0.829 0.162
M45.X6 Ankylosing spondylitis (Lumbar region)
0.170 0.830 0.000
E89.2 Postprocedural hypoparathyroidism
0.001 0.832 0.167
N18.3 Chronic kidney disease, stage 3
0.000 0.833 0.167
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.001 0.833 0.166
E74.3 Other disorders of intestinal carbohydrate absorption
0.003 0.834 0.162
E20.9 Hypoparathyroidism, unspecified
0.001 0.834 0.165
E27.5 Adrenomedullary hyperfunction
0.001 0.836 0.164
E27.0 Other adrenocortical overactivity
0.001 0.836 0.164
E79 Disorders of purine and pyrimidine metabolism
0.009 0.836 0.155
E89.3 Postprocedural hypopituitarism
0.001 0.838 0.161
E84 Cystic fibrosis
0.010 0.838 0.152
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.160 0.840 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.160 0.840 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.160 0.840 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.160 0.840 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.160 0.840 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.160 0.840 0.000
N18.4 Chronic kidney disease, stage 4
0.000 0.842 0.158
E22.0 Acromegaly and pituitary gigantism
0.000 0.844 0.156
E34.9 Endocrine disorder, unspecified
0.000 0.847 0.153
N18.2 Chronic kidney disease, stage 2
0.000 0.847 0.153
E27.8 Other specified disorders of adrenal gland
0.000 0.848 0.151
D64.8 Other specified anaemias
0.001 0.850 0.149
E88 Other metabolic disorders
0.006 0.850 0.144
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.001 0.851 0.148
E89.8 Other postprocedural endocrine and metabolic disorders
0.001 0.851 0.148
E89.5 Postprocedural testicular hypofunction
0.001 0.851 0.148
E89.1 Postprocedural hypoinsulinaemia
0.001 0.851 0.148
E73 Lactose intolerance
0.010 0.854 0.137
E89.0 Postprocedural hypothyroidism
0.000 0.854 0.146
E23.0 Hypopituitarism
0.000 0.854 0.145
E74.9 Disorder of carbohydrate metabolism, unspecified
0.005 0.855 0.140
E74.8 Other specified disorders of carbohydrate metabolism
0.005 0.855 0.140
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.005 0.855 0.140
E74.2 Disorders of galactose metabolism
0.005 0.855 0.140
E74.1 Disorders of fructose metabolism
0.005 0.855 0.140
E74.0 Glycogen storage disease
0.005 0.855 0.140
N18.8 Other chronic renal failure
0.000 0.858 0.142
E34.0 Carcinoid syndrome
0.001 0.858 0.141
E78.8 Other disorders of lipoprotein metabolism
0.001 0.860 0.139
E61 Deficiency of other nutrient elements
0.000 0.860 0.140
E89.4 Postprocedural ovarian failure
0.001 0.860 0.139
E78.3 Hyperchylomicronaemia
0.001 0.860 0.138
E21.0 Primary hyperparathyroidism
0.000 0.861 0.139
M45.X2 Ankylosing spondylitis (Cervical region)
0.138 0.862 0.000
E78.4 Other hyperlipidaemia
0.001 0.865 0.134
E85 Amyloidosis
0.009 0.865 0.126
E51.2 Wernicke's encephalopathy
0.000 0.867 0.133
E51.9 Thiamine deficiency, unspecified
0.000 0.867 0.133
E51.8 Other manifestations of thiamine deficiency
0.000 0.867 0.133
E51.1 Beriberi
0.000 0.867 0.133
E50.9 Vitamin A deficiency, unspecified
0.000 0.867 0.133
E50.8 Other manifestations of vitamin A deficiency
0.000 0.867 0.133
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.867 0.133
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.867 0.133
E50.5 Vitamin A deficiency with night blindness
0.000 0.867 0.133
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.867 0.133
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.867 0.133
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.867 0.133
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.867 0.133
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.867 0.133
E63.9 Nutritional deficiency, unspecified
0.000 0.867 0.133
E63.8 Other specified nutritional deficiencies
0.000 0.867 0.133
E63.1 Imbalance of constituents of food intake
0.000 0.867 0.133
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.867 0.133
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.867 0.133
E64.8 Sequelae of other nutritional deficiencies
0.000 0.867 0.133
E64.3 Sequelae of rickets
0.000 0.867 0.133
E64.2 Sequelae of vitamin C deficiency
0.000 0.867 0.133
E64.1 Sequelae of vitamin A deficiency
0.000 0.867 0.133
E64.0 Sequelae of protein-energy malnutrition
0.000 0.867 0.133
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.006 0.870 0.124
E70.8 Other disorders of aromatic amino-acid metabolism
0.006 0.870 0.124
E70.3 Albinism
0.006 0.870 0.124
E70.2 Disorders of tyrosine metabolism
0.006 0.870 0.124
E70.1 Other hyperphenylalaninaemias
0.006 0.870 0.124
E70.0 Classical phenylketonuria
0.006 0.870 0.124
E71.3 Disorders of fatty-acid metabolism
0.006 0.870 0.124
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.006 0.870 0.124
E71.1 Other disorders of branched-chain amino-acid metabolism
0.006 0.870 0.124
E71.0 Maple-syrup-urine disease
0.006 0.870 0.124
E75.6 Lipid storage disorder, unspecified
0.006 0.870 0.124
E75.5 Other lipid storage disorders
0.006 0.870 0.124
E75.4 Neuronal ceroid lipofuscinosis
0.006 0.870 0.124
E75.3 Sphingolipidosis, unspecified
0.006 0.870 0.124
E75.2 Other sphingolipidosis
0.006 0.870 0.124
E75.1 Other gangliosidosis
0.006 0.870 0.124
E75.0 GM2 gangliosidosis
0.006 0.870 0.124
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.006 0.870 0.124
E76.8 Other disorders of glucosaminoglycan metabolism
0.006 0.870 0.124
E76.3 Mucopolysaccharidosis, unspecified
0.006 0.870 0.124
E76.2 Other mucopolysaccharidoses
0.006 0.870 0.124
E76.1 Mucopolysaccharidosis, type II
0.006 0.870 0.124
E76.0 Mucopolysaccharidosis, type I
0.006 0.870 0.124
E77.9 Disorder of glycoprotein metabolism, unspecified
0.006 0.870 0.124
E77.8 Other disorders of glycoprotein metabolism
0.006 0.870 0.124
E77.1 Defects in glycoprotein degradation
0.006 0.870 0.124
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.006 0.870 0.124
E53 Deficiency of other B group vitamins
0.000 0.873 0.127
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.875 0.125
E56.9 Vitamin deficiency, unspecified
0.001 0.876 0.123
E56.8 Deficiency of other vitamins
0.001 0.876 0.123
E56.0 Deficiency of vitamin E
0.001 0.876 0.123
E72.9 Disorder of amino-acid metabolism, unspecified
0.007 0.877 0.116
E72.8 Other specified disorders of amino-acid metabolism
0.007 0.877 0.116
E72.5 Disorders of glycine metabolism
0.007 0.877 0.116
E72.4 Disorders of ornithine metabolism
0.007 0.877 0.116
E72.3 Disorders of lysine and hydroxylysine metabolism
0.007 0.877 0.116
E72.2 Disorders of urea cycle metabolism
0.007 0.877 0.116
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.007 0.877 0.116
D60-D64 Aplastic and other anaemias
0.001 0.878 0.121
J47 Bronchiectasis
0.120 0.880 0.000
E55 Vitamin D deficiency
0.001 0.881 0.118
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.007 0.882 0.111
E79.8 Other disorders of purine and pyrimidine metabolism
0.007 0.882 0.111
E79.1 Lesch-Nyhan syndrome
0.007 0.882 0.111
E84.8 Cystic fibrosis with other manifestations
0.007 0.884 0.109
E84.1 Cystic fibrosis with intestinal manifestations
0.007 0.884 0.109
E84.0 Cystic fibrosis with pulmonary manifestations
0.007 0.884 0.109
E27.2 Addisonian crisis
0.001 0.885 0.114
E80 Disorders of porphyrin and bilirubin metabolism
0.009 0.886 0.105
E72.0 Disorders of amino-acid transport
0.007 0.887 0.105
E88.2 Lipomatosis, not elsewhere classified
0.004 0.888 0.108
E56.1 Deficiency of vitamin K
0.001 0.890 0.110
E88.3 Tumour lysis syndrome
0.004 0.891 0.105
E88.9 Metabolic disorder, unspecified
0.005 0.892 0.103
E88.8 Other specified metabolic disorders
0.005 0.892 0.103
E73.8 Other lactose intolerance
0.007 0.895 0.098
E73.1 Secondary lactase deficiency
0.007 0.895 0.098
E73.0 Congenital lactase deficiency
0.007 0.895 0.098
N18.1 Chronic kidney disease, stage 1
0.000 0.896 0.104
N18.5 Chronic kidney disease, stage 5
0.000 0.897 0.103
E61.9 Deficiency of nutrient element, unspecified
0.000 0.899 0.100
E61.8 Deficiency of other specified nutrient elements
0.000 0.899 0.100
E61.7 Deficiency of multiple nutrient elements
0.000 0.899 0.100
E61.6 Vanadium deficiency
0.000 0.899 0.100
E61.5 Molybdenum deficiency
0.000 0.899 0.100
E61.4 Chromium deficiency
0.000 0.899 0.100
E61.3 Manganese deficiency
0.000 0.899 0.100
E61.0 Copper deficiency
0.000 0.899 0.100
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.008 0.900 0.093
E88.1 Lipodystrophy, not elsewhere classified
0.005 0.900 0.095
K50-K52 Noninfective enteritis and colitis
0.099 0.901 0.000
E66 Obesity
0.000 0.902 0.098
M45-M49 Spondylopathies
0.098 0.902 0.000
E85.8 Other amyloidosis
0.007 0.903 0.091
E85.2 Heredofamilial amyloidosis, unspecified
0.007 0.903 0.091
E85.1 Neuropathic heredofamilial amyloidosis
0.007 0.903 0.091
E85.0 Nonneuropathic heredofamilial amyloidosis
0.007 0.903 0.091
E84.9 Cystic fibrosis, unspecified
0.008 0.903 0.089
D61 Other aplastic anaemias
0.001 0.904 0.096
N18.0 End-stage renal disease
0.000 0.905 0.095
E85.9 Amyloidosis, unspecified
0.006 0.907 0.088
E61.2 Magnesium deficiency
0.000 0.908 0.092

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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