TreeWAS – Variant ID: rs3135753

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I50 Heart failure	0.011	0.989	0.000
I30-I52 Other forms of heart disease	0.011	0.989	0.000
I50.0 Congestive heart failure	0.010	0.989	0.000
I50.1 Left ventricular failure	0.010	0.990	0.000
R11 Nausea and vomiting	0.000	0.990	0.010
I49 Other cardiac arrhythmias	0.010	0.990	0.000
I51 Complications and ill-defined descriptions of heart disease	0.009	0.991	0.000
I50.9 Heart failure, unspecified	0.009	0.991	0.000
I44 Atrioventricular and left bundle-branch block	0.009	0.991	0.000
I46 Cardiac arrest	0.009	0.991	0.000
I49.3 Ventricular premature depolarisation	0.009	0.991	0.000
I51.7 Cardiomegaly	0.009	0.991	0.000
I35 Nonrheumatic aortic valve disorders	0.008	0.992	0.000
I44.0 Atrioventricular block, first degree	0.008	0.992	0.000
I42 Cardiomyopathy	0.008	0.992	0.000
I52 Other heart disorders in diseases classified elsewhere	0.008	0.992	0.000
I48 Atrial fibrillation and flutter	0.008	0.992	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.008	0.992	0.000
I41 Myocarditis in diseases classified elsewhere	0.008	0.992	0.000
I40 Acute myocarditis	0.008	0.992	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.008	0.992	0.000
I37 Pulmonary valve disorders	0.008	0.992	0.000
I36 Nonrheumatic tricuspid valve disorders	0.008	0.992	0.000
I33 Acute and subacute endocarditis	0.008	0.992	0.000
I32 Pericarditis in diseases classified elsewhere	0.008	0.992	0.000
I31 Other diseases of pericardium	0.008	0.992	0.000
I30 Acute pericarditis	0.008	0.992	0.000
I38 Endocarditis, valve unspecified	0.008	0.992	0.000
I34 Nonrheumatic mitral valve disorders	0.008	0.992	0.000
I46.0 Cardiac arrest with successful resuscitation	0.008	0.992	0.000
I49.5 Sick sinus syndrome	0.008	0.992	0.000
R10.1 Pain localised to upper abdomen	0.000	0.992	0.008
I44.1 Atrioventricular block, second degree	0.007	0.993	0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.000	0.993	0.007
I44.2 Atrioventricular block, complete	0.007	0.993	0.000
I49.8 Other specified cardiac arrhythmias	0.007	0.993	0.000
I49.4 Other and unspecified premature depolarisation	0.007	0.993	0.000
I49.2 Junctional premature depolarisation	0.007	0.993	0.000
I49.1 Atrial premature depolarisation	0.007	0.993	0.000
I49.0 Ventricular fibrillation and flutter	0.007	0.993	0.000
I45 Other conduction disorders	0.007	0.993	0.000
I49.9 Cardiac arrhythmia, unspecified	0.007	0.993	0.000
R10 Abdominal and pelvic pain	0.000	0.993	0.007
I51.9 Heart disease, unspecified	0.007	0.993	0.000
I51.6 Cardiovascular disease, unspecified	0.007	0.993	0.000
I51.5 Myocardial degeneration	0.007	0.993	0.000
I51.4 Myocarditis, unspecified	0.007	0.993	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.007	0.993	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.007	0.993	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.007	0.993	0.000
I51.0 Cardiac septal defect, acquired	0.007	0.993	0.000
I35.1 Aortic (valve) insufficiency	0.007	0.993	0.000
I44.6 Other and unspecified fascicular block	0.007	0.993	0.000
I44.5 Left posterior fascicular block	0.007	0.993	0.000
I44.4 Left anterior fascicular block	0.007	0.993	0.000
I44.3 Other and unspecified atrioventricular block	0.007	0.993	0.000
I51.8 Other ill-defined heart diseases	0.007	0.993	0.000
I46.9 Cardiac arrest, unspecified	0.007	0.993	0.000
I46.1 Sudden cardiac death, so described	0.007	0.993	0.000
I47 Paroxysmal tachycardia	0.007	0.993	0.000
R18 Ascites	0.000	0.994	0.006
I42.0 Dilated cardiomyopathy	0.006	0.994	0.000
I35.9 Aortic valve disorder, unspecified	0.006	0.994	0.000
I35.8 Other aortic valve disorders	0.006	0.994	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.006	0.994	0.000
I44.7 Left bundle-branch block, unspecified	0.006	0.994	0.000
I42.9 Cardiomyopathy, unspecified	0.006	0.994	0.000
I42.8 Other cardiomyopathies	0.006	0.994	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.006	0.994	0.000
I42.6 Alcoholic cardiomyopathy	0.006	0.994	0.000
I42.5 Other restrictive cardiomyopathy	0.006	0.994	0.000
I42.4 Endocardial fibroelastosis	0.006	0.994	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.006	0.994	0.000
I42.2 Other hypertrophic cardiomyopathy	0.006	0.994	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.006	0.994	0.000
I35.0 Aortic (valve) stenosis	0.006	0.994	0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.006	0.994	0.000
R13 Dysphagia	0.000	0.994	0.006
R10.4 Other and unspecified abdominal pain	0.000	0.994	0.006
R12 Heartburn	0.000	0.994	0.006
I30.9 Acute pericarditis, unspecified	0.006	0.994	0.000
I30.8 Other forms of acute pericarditis	0.006	0.994	0.000
I30.1 Infective pericarditis	0.006	0.994	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.006	0.994	0.000
I31.9 Disease of pericardium, unspecified	0.006	0.994	0.000
I31.8 Other specified diseases of pericardium	0.006	0.994	0.000
I31.3 Pericardial effusion (noninflammatory)	0.006	0.994	0.000
I31.2 Haemopericardium, not elsewhere classified	0.006	0.994	0.000
I31.1 Chronic constrictive pericarditis	0.006	0.994	0.000
I31.0 Chronic adhesive pericarditis	0.006	0.994	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.006	0.994	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.006	0.994	0.000
I33.9 Acute endocarditis, unspecified	0.006	0.994	0.000
I33.0 Acute and subacute infective endocarditis	0.006	0.994	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.006	0.994	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.006	0.994	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.006	0.994	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.006	0.994	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.006	0.994	0.000
I37.9 Pulmonary valve disorder, unspecified	0.006	0.994	0.000
I37.8 Other pulmonary valve disorders	0.006	0.994	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.006	0.994	0.000
I37.1 Pulmonary valve insufficiency	0.006	0.994	0.000
I37.0 Pulmonary valve stenosis	0.006	0.994	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.006	0.994	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.006	0.994	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.006	0.994	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.006	0.994	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.006	0.994	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.006	0.994	0.000
I40.9 Acute myocarditis, unspecified	0.006	0.994	0.000
I40.8 Other acute myocarditis	0.006	0.994	0.000
I40.1 Isolated myocarditis	0.006	0.994	0.000
I40.0 Infective myocarditis	0.006	0.994	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.006	0.994	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.006	0.994	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.006	0.994	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.006	0.994	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.006	0.994	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.006	0.994	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.006	0.994	0.000
I48.4 Atypical atrial flutter	0.006	0.994	0.000
I48.3 Typical atrial flutter	0.006	0.994	0.000
I48.2 Chronic atrial fibrillation	0.006	0.994	0.000
I48.1 Persistent atrial fibrillation	0.006	0.994	0.000
I48.0 Paroxysmal atrial fibrillation	0.006	0.994	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.006	0.994	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.006	0.994	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.006	0.994	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.006	0.994	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.006	0.994	0.000
I34.1 Mitral (valve) prolapse	0.006	0.994	0.000
I34.0 Mitral (valve) insufficiency	0.006	0.994	0.000
T81 Complications of procedures, not elsewhere classified	0.006	0.994	0.000
R15 Faecal incontinence	0.000	0.994	0.006
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.006	0.994	0.000
R14 Flatulence and related conditions	0.000	0.994	0.006
R17 Unspecified jaundice	0.000	0.994	0.006
I45.9 Conduction disorder, unspecified	0.005	0.995	0.000
I45.8 Other specified conduction disorders	0.005	0.995	0.000
I45.6 Preexcitation syndrome	0.005	0.995	0.000
I45.5 Other specified heart block	0.005	0.995	0.000
I45.4 Nonspecific intraventricular block	0.005	0.995	0.000
I45.3 Trifascicular block	0.005	0.995	0.000
I45.2 Bifascicular block	0.005	0.995	0.000
I45.0 Right fascicular block	0.005	0.995	0.000
R10.0 Acute abdomen	0.000	0.995	0.005
I47.2 Ventricular tachycardia	0.005	0.995	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.005	0.995	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.005	0.995	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.005	0.995	0.000
I47.0 Reentry ventricular arrhythmia	0.005	0.995	0.000
T81.8 Other complications of procedures, not elsewhere classified	0.005	0.995	0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.000	0.995	0.005
T81.4 Infection following a procedure, not elsewhere classified	0.005	0.995	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.005	0.995	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.005	0.995	0.000
I45.1 Other and unspecified right bundle-branch block	0.004	0.995	0.000
T82.1 Mechanical complication of cardiac electronic device	0.005	0.995	0.000
R10.2 Pelvic and perineal pain	0.000	0.995	0.004
N19 Unspecified renal failure	0.005	0.995	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.005	0.995	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.004	0.995	0.000
T81.9 Unspecified complication of procedure	0.004	0.995	0.000
T81.7 Vascular complications following a procedure, not elsewhere classified	0.004	0.995	0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.004	0.995	0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.004	0.995	0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.004	0.995	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.004	0.996	0.000
T87 Complications peculiar to reattachment and amputation	0.004	0.996	0.000
T86 Failure and rejection of transplanted organs and tissues	0.004	0.996	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.004	0.996	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.004	0.996	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.004	0.996	0.000
J45.9 Asthma, unspecified	0.000	0.996	0.004
T84.1 Mechanical complication of internal fixation device of bones of limb	0.004	0.996	0.000
S60-S69 Injuries to the wrist and hand	0.004	0.996	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.004	0.996	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.004	0.996	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.004	0.996	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.004	0.996	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.004	0.996	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.004	0.996	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.004	0.996	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.004	0.996	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.004	0.996	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.004	0.996	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.004	0.996	0.000
T82.3 Mechanical complication of other vascular grafts	0.004	0.996	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.004	0.996	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.004	0.996	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.004	0.996	0.000
N17-N19 Renal failure	0.004	0.996	0.000
S70-S79 Injuries to the hip and thigh	0.004	0.996	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.004	0.996	0.000
I21 Acute myocardial infarction	0.004	0.996	0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.000	0.996	0.003
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.996	0.003
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.004	0.996	0.000
S61 Open wound of wrist and hand	0.004	0.996	0.000
Chapter IX Diseases of the circulatory system	0.004	0.996	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.004	0.996	0.000
S50-S59 Injuries to the elbow and forearm	0.003	0.996	0.000
I47.1 Supraventricular tachycardia	0.003	0.996	0.000
S00-S09 Injuries to the head	0.003	0.996	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.003	0.996	0.000
T79-T79 Certain early complications of trauma	0.003	0.996	0.000
T66-T78 Other and unspecified effects of external causes	0.003	0.996	0.000
T33-T35 Frostbite	0.003	0.996	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.003	0.996	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.003	0.996	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.003	0.996	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.003	0.996	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.003	0.996	0.000
T00-T07 Injuries involving multiple body regions	0.003	0.996	0.000
S90-S99 Injuries to the ankle and foot	0.003	0.996	0.000
S40-S49 Injuries to the shoulder and upper arm	0.003	0.996	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.003	0.996	0.000
S20-S29 Injuries to the thorax	0.003	0.996	0.000
S10-S19 Injuries to the neck	0.003	0.996	0.000
E10.9 Without complications	0.003	0.996	0.000
I21.9 Acute myocardial infarction, unspecified	0.003	0.996	0.000
N18 Chronic renal failure	0.003	0.996	0.000
S68 Traumatic amputation of wrist and hand	0.003	0.996	0.000
S80-S89 Injuries to the knee and lower leg	0.003	0.996	0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.003	0.997	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.003	0.997	0.000
T80.6 Other serum reactions	0.003	0.997	0.000
T80.5 Anaphylactic shock due to serum	0.003	0.997	0.000
T80.4 Rh incompatibility reaction	0.003	0.997	0.000
T80.3 ABO incompatibility reaction	0.003	0.997	0.000
T80.2 Infections following infusion, transfusion and therapeutic injection	0.003	0.997	0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.003	0.997	0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.003	0.997	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.003	0.997	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.003	0.997	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.003	0.997	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.003	0.997	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.003	0.997	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.003	0.997	0.000
T83.2 Mechanical complication of graft of urinary organ	0.003	0.997	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.003	0.997	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.003	0.997	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.003	0.997	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.003	0.997	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.003	0.997	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.003	0.997	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.003	0.997	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.003	0.997	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.003	0.997	0.000
T85.2 Mechanical complication of intraocular lens	0.003	0.997	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.003	0.997	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.003	0.997	0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.003	0.997	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.003	0.997	0.000
T86.4 Liver transplant failure and rejection	0.003	0.997	0.000
T86.3 Heart-lung transplant failure and rejection	0.003	0.997	0.000
T86.2 Heart transplant failure and rejection	0.003	0.997	0.000
T86.1 Kidney transplant failure and rejection	0.003	0.997	0.000
T86.0 Bone-marrow transplant rejection	0.003	0.997	0.000
T87.6 Other and unspecified complications of amputation stump	0.003	0.997	0.000
T87.5 Necrosis of amputation stump	0.003	0.997	0.000
T87.4 Infection of amputation stump	0.003	0.997	0.000
T87.3 Neuroma of amputation stump	0.003	0.997	0.000
T87.2 Complications of other reattached body part	0.003	0.997	0.000
T87.1 Complications of reattached (part of) lower extremity	0.003	0.997	0.000
T87.0 Complications of reattached (part of) upper extremity	0.003	0.997	0.000
T88.9 Complication of surgical and medical care, unspecified	0.003	0.997	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.003	0.997	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.003	0.997	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.003	0.997	0.000
T88.5 Other complications of anaesthesia	0.003	0.997	0.000
T88.4 Failed or difficult intubation	0.003	0.997	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.003	0.997	0.000
T88.2 Shock due to anaesthesia	0.003	0.997	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.003	0.997	0.000
T88.0 Infection following immunisation	0.003	0.997	0.000
N17 Acute renal failure	0.003	0.997	0.000
S72 Fracture of femur	0.003	0.997	0.000
R10.3 Pain localised to other parts of lower abdomen	0.000	0.997	0.003
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.003	0.997	0.000
S61.8 Open wound of other parts of wrist and hand	0.003	0.997	0.000
I20-I25 Ischaemic heart diseases	0.003	0.997	0.000
S69 Other and unspecified injuries of wrist and hand	0.003	0.997	0.000
S67 Crushing injury of wrist and hand	0.003	0.997	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.003	0.997	0.000
S65 Injury of blood vessels at wrist and hand level	0.003	0.997	0.000
S64 Injury of nerves at wrist and hand level	0.003	0.997	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.003	0.997	0.000
S62 Fracture at wrist and hand level	0.003	0.997	0.000
S60 Superficial injury of wrist and hand	0.003	0.997	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.003	0.997	0.000
R19 Other symptoms and signs involving the digestive system and abdomen	0.000	0.997	0.003
N18.5 Chronic kidney disease, stage 5	0.003	0.997	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.003	0.997	0.000
R16.1 Splenomegaly, not elsewhere classified	0.001	0.997	0.003
S61.0 Open wound of finger(s) without damage to nail	0.003	0.997	0.000
N17.9 Acute renal failure, unspecified	0.003	0.997	0.000
N18.4 Chronic kidney disease, stage 4	0.003	0.997	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.003	0.997	0.000
I05-I09 Chronic rheumatic heart diseases	0.003	0.997	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.003	0.997	0.000
S79 Other and unspecified injuries of hip and thigh	0.003	0.997	0.000
S78 Traumatic amputation of hip and thigh	0.003	0.997	0.000
S77 Crushing injury of hip and thigh	0.003	0.997	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.003	0.997	0.000
S75 Injury of blood vessels at hip and thigh level	0.003	0.997	0.000
S74 Injury of nerves at hip and thigh level	0.003	0.997	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.003	0.997	0.000
S71 Open wound of hip and thigh	0.003	0.997	0.000
S70 Superficial injury of hip and thigh	0.003	0.997	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.003	0.997	0.000
I21.4 Acute subendocardial myocardial infarction	0.003	0.997	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.003	0.997	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.003	0.997	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.003	0.997	0.000
S72.0 Fracture of neck of femur	0.003	0.997	0.000
S52 Fracture of forearm	0.003	0.997	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.003	0.997	0.000
S61.7 Multiple open wounds of wrist and hand	0.003	0.997	0.000
S61.1 Open wound of finger(s) with damage to nail	0.003	0.997	0.000
S72.1 Pertrochanteric fracture	0.003	0.997	0.000
S02 Fracture of skull and facial bones	0.003	0.997	0.000
S01 Open wound of head	0.003	0.997	0.000
I00-I02 Acute rheumatic fever	0.003	0.997	0.000
S59 Other and unspecified injuries of forearm	0.003	0.997	0.000
S58 Traumatic amputation of forearm	0.003	0.997	0.000
S57 Crushing injury of forearm	0.003	0.997	0.000
S56 Injury of muscle and tendon at forearm level	0.003	0.997	0.000
S55 Injury of blood vessels at forearm level	0.003	0.997	0.000
S54 Injury of nerves at forearm level	0.003	0.997	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.003	0.997	0.000
S51 Open wound of forearm	0.003	0.997	0.000
S50 Superficial injury of forearm	0.003	0.997	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.003	0.997	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.003	0.997	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.003	0.997	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.003	0.997	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.003	0.997	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.003	0.997	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.003	0.997	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
T36 Poisoning by systemic antibiotics	0.003	0.997	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.003	0.997	0.000
J45 Asthma	0.000	0.997	0.002
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.003	0.997	0.000
S08 Traumatic amputation of part of head	0.003	0.997	0.000
S07 Crushing injury of head	0.003	0.997	0.000
S06 Intracranial injury	0.003	0.997	0.000
S05 Injury of eye and orbit	0.003	0.997	0.000
S04 Injury of cranial nerves	0.003	0.997	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.003	0.997	0.000
S19 Other and unspecified injuries of neck	0.003	0.997	0.000
S17 Crushing injury of neck	0.003	0.997	0.000
S15 Injury of blood vessels at neck level	0.003	0.997	0.000
S14 Injury of nerves and spinal cord at neck level	0.003	0.997	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.003	0.997	0.000
S12 Fracture of neck	0.003	0.997	0.000
S11 Open wound of neck	0.003	0.997	0.000
S10 Superficial injury of neck	0.003	0.997	0.000
S18 Traumatic amputation at neck level	0.003	0.997	0.000
S16 Injury of muscle and tendon at neck level	0.003	0.997	0.000
S29 Other and unspecified injuries of thorax	0.003	0.997	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.003	0.997	0.000
S27 Injury of other and unspecified intrathoracic organs	0.003	0.997	0.000
S26 Injury of heart	0.003	0.997	0.000
S25 Injury of blood vessels of thorax	0.003	0.997	0.000
S24 Injury of nerves and spinal cord at thorax level	0.003	0.997	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.003	0.997	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.003	0.997	0.000
S21 Open wound of thorax	0.003	0.997	0.000
S20 Superficial injury of thorax	0.003	0.997	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.003	0.997	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.003	0.997	0.000
S37 Injury of urinary and pelvic organs	0.003	0.997	0.000
S36 Injury of intra-abdominal organs	0.003	0.997	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.003	0.997	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.003	0.997	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.003	0.997	0.000
S32 Fracture of lumbar spine and pelvis	0.003	0.997	0.000
S31 Open wound of abdomen, lower back and pelvis	0.003	0.997	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.003	0.997	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.003	0.997	0.000
S48 Traumatic amputation of shoulder and upper arm	0.003	0.997	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.003	0.997	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.003	0.997	0.000
S44 Injury of nerves at shoulder and upper arm level	0.003	0.997	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.003	0.997	0.000
S42 Fracture of shoulder and upper arm	0.003	0.997	0.000
S41 Open wound of shoulder and upper arm	0.003	0.997	0.000
S40 Superficial injury of shoulder and upper arm	0.003	0.997	0.000
S47 Crushing injury of shoulder and upper arm	0.003	0.997	0.000
S99 Other and unspecified injuries of ankle and foot	0.003	0.997	0.000
S98 Traumatic amputation of ankle and foot	0.003	0.997	0.000
S97 Crushing injury of ankle and foot	0.003	0.997	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.003	0.997	0.000
S95 Injury of blood vessels at ankle and foot level	0.003	0.997	0.000
S94 Injury of nerves at ankle and foot level	0.003	0.997	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.003	0.997	0.000
S92 Fracture of foot, except ankle	0.003	0.997	0.000
S91 Open wound of ankle and foot	0.003	0.997	0.000
S90 Superficial injury of ankle and foot	0.003	0.997	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.003	0.997	0.000
T05 Traumatic amputations involving multiple body regions	0.003	0.997	0.000
T04 Crushing injuries involving multiple body regions	0.003	0.997	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.003	0.997	0.000
T02 Fractures involving multiple body regions	0.003	0.997	0.000
T01 Open wounds involving multiple body regions	0.003	0.997	0.000
T00 Superficial injuries involving multiple body regions	0.003	0.997	0.000
T07 Unspecified multiple injuries	0.003	0.997	0.000
T14 Injury of unspecified body region	0.003	0.997	0.000
T13 Other injuries of lower limb, level unspecified	0.003	0.997	0.000
T11 Other injuries of upper limb, level unspecified	0.003	0.997	0.000
T09 Other injuries of spine and trunk, level unspecified	0.003	0.997	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.003	0.997	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.003	0.997	0.000
T12 Fracture of lower limb, level unspecified	0.003	0.997	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.003	0.997	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.003	0.997	0.000
T10 Fracture of upper limb, level unspecified	0.003	0.997	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.003	0.997	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.003	0.997	0.000
T08 Fracture of spine, level unspecified	0.003	0.997	0.000
T19 Foreign body in genito-urinary tract	0.003	0.997	0.000
T18 Foreign body in alimentary tract	0.003	0.997	0.000
T17 Foreign body in respiratory tract	0.003	0.997	0.000
T15 Foreign body on external eye	0.003	0.997	0.000
T16 Foreign body in ear	0.003	0.997	0.000
T25 Burn and corrosion of ankle and foot	0.003	0.997	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.003	0.997	0.000
T23 Burn and corrosion of wrist and hand	0.003	0.997	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
T21 Burn and corrosion of trunk	0.003	0.997	0.000
T20 Burn and corrosion of head and neck	0.003	0.997	0.000
T28 Burn and corrosion of other internal organs	0.003	0.997	0.000
T27 Burn and corrosion of respiratory tract	0.003	0.997	0.000
T26 Burn and corrosion confined to eye and adnexa	0.003	0.997	0.000
T32 Corrosions classified according to extent of body surface involved	0.003	0.997	0.000
T31 Burns classified according to extent of body surface involved	0.003	0.997	0.000
T30 Burn and corrosion, body region unspecified	0.003	0.997	0.000
T29 Burns and corrosions of multiple body regions	0.003	0.997	0.000
T35 Frostbite involving multiple body regions and unspecified frostbite	0.003	0.997	0.000
T34 Frostbite with tissue necrosis	0.003	0.997	0.000
T33 Superficial frostbite	0.003	0.997	0.000
T78 Adverse effects, not elsewhere classified	0.003	0.997	0.000
T75 Effects of other external causes	0.003	0.997	0.000
T74 Maltreatment syndromes	0.003	0.997	0.000
T73 Effects of other deprivation	0.003	0.997	0.000
T70 Effects of air pressure and water pressure	0.003	0.997	0.000
T69 Other effects of reduced temperature	0.003	0.997	0.000
T67 Effects of heat and light	0.003	0.997	0.000
T71 Asphyxiation	0.003	0.997	0.000
T68 Hypothermia	0.003	0.997	0.000
T66 Unspecified effects of radiation	0.003	0.997	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.003	0.997	0.000
T98 Sequelae of other and unspecified effects of external causes	0.003	0.997	0.000
T95 Sequelae of burns, corrosions and frostbite	0.003	0.997	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.003	0.997	0.000
T93 Sequelae of injuries of lower limb	0.003	0.997	0.000
T92 Sequelae of injuries of upper limb	0.003	0.997	0.000
T91 Sequelae of injuries of neck and trunk	0.003	0.997	0.000
T90 Sequelae of injuries of head	0.003	0.997	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.003	0.997	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.003	0.997	0.000
N18.8 Other chronic renal failure	0.003	0.997	0.000
N18.2 Chronic kidney disease, stage 2	0.003	0.997	0.000
N18.1 Chronic kidney disease, stage 1	0.003	0.997	0.000
N18.0 End-stage renal disease	0.003	0.997	0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.003	0.997	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.003	0.997	0.000
S68.4 Traumatic amputation of hand at wrist level	0.003	0.997	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.003	0.997	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.003	0.997	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.003	0.997	0.000
S89 Other and unspecified injuries of lower leg	0.003	0.997	0.000
S88 Traumatic amputation of lower leg	0.003	0.997	0.000
S87 Crushing injury of lower leg	0.003	0.997	0.000
S86 Injury of muscle and tendon at lower leg level	0.003	0.997	0.000
S85 Injury of blood vessels at lower leg level	0.003	0.997	0.000
S84 Injury of nerves at lower leg level	0.003	0.997	0.000
S81 Open wound of lower leg	0.003	0.997	0.000
S80 Superficial injury of lower leg	0.003	0.997	0.000
N17.8 Other acute renal failure	0.003	0.997	0.000
N17.2 Acute renal failure with medullary necrosis	0.003	0.997	0.000
N17.1 Acute renal failure with acute cortical necrosis	0.003	0.997	0.000
N17.0 Acute renal failure with tubular necrosis	0.003	0.997	0.000
S72.9 Fracture of femur, part unspecified	0.003	0.997	0.000
S72.8 Fractures of other parts of femur	0.003	0.997	0.000
S72.7 Multiple fractures of femur	0.003	0.997	0.000
S72.4 Fracture of lower end of femur	0.003	0.997	0.000
S72.3 Fracture of shaft of femur	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations