TreeWAS – Variant ID: rs34305371

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K80.1 Calculus of gallbladder with other cholecystitis	0.061	0.939	0.000
C25.0 Head of pancreas	0.022	0.978	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.021	0.979	0.000
C25 Malignant neoplasm of pancreas	0.021	0.979	0.000
C25.9 Pancreas, unspecified	0.020	0.980	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.018	0.982	0.000
C25.3 Pancreatic duct	0.017	0.983	0.000
C25.2 Tail of pancreas	0.016	0.984	0.000
C25.1 Body of pancreas	0.016	0.984	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.016	0.984	0.000
C25.8 Overlapping lesion of pancreas	0.015	0.985	0.000
C25.7 Other parts of pancreas	0.015	0.985	0.000
C25.4 Endocrine pancreas	0.015	0.985	0.000
K80 Cholelithiasis	0.014	0.986	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.014	0.986	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.013	0.987	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.012	0.988	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.012	0.988	0.000
S42.00 Fracture of clavicle (closed)	0.012	0.988	0.000
S42.10 Fracture of scapula (closed)	0.011	0.989	0.000
K80.3 Calculus of bile duct with cholangitis	0.010	0.989	0.000
S42.0 Fracture of clavicle	0.011	0.989	0.000
S42.1 Fracture of scapula	0.010	0.990	0.000
K80.8 Other cholelithiasis	0.010	0.990	0.000
S42 Fracture of shoulder and upper arm	0.010	0.990	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.009	0.991	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.009	0.991	0.000
C15-C26 Malignant neoplasms of digestive organs	0.009	0.991	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.009	0.991	0.000
K86.2 Cyst of pancreas	0.008	0.992	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.008	0.992	0.000
C23 Malignant neoplasm of gallbladder	0.008	0.992	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.008	0.992	0.000
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.008	0.992	0.000
S42.01 Fracture of clavicle (open)	0.008	0.992	0.000
S42.4 Fracture of lower end of humerus	0.008	0.992	0.000
K80.4 Calculus of bile duct with cholecystitis	0.008	0.992	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.008	0.992	0.000
S42.11 Fracture of scapula (open)	0.008	0.992	0.000
C26.0 Intestinal tract, part unspecified	0.007	0.992	0.000
S42.3 Fracture of shaft of humerus	0.007	0.993	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.007	0.993	0.000
K86 Other diseases of pancreas	0.007	0.993	0.000
C17 Malignant neoplasm of small intestine	0.007	0.993	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.007	0.993	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.007	0.993	0.000
C18.2 Ascending colon	0.007	0.993	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.007	0.993	0.000
K85 Acute pancreatitis	0.007	0.993	0.000
M79.86 Other specified soft tissue disorders (Lower leg)	0.000	0.993	0.007
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.007	0.993	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.007	0.993	0.000
C21 Malignant neoplasm of anus and anal canal	0.007	0.993	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.007	0.993	0.000
C15 Malignant neoplasm of oesophagus	0.007	0.993	0.000
C26.9 Ill-defined sites within the digestive system	0.006	0.993	0.000
C16 Malignant neoplasm of stomach	0.007	0.993	0.000
C18 Malignant neoplasm of colon	0.006	0.994	0.000
K85.9 Acute pancreatitis, unspecified	0.006	0.994	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.006	0.994	0.000
C26.8 Overlapping lesion of digestive system	0.006	0.994	0.000
C26.1 Spleen	0.006	0.994	0.000
S42.2 Fracture of upper end of humerus	0.006	0.994	0.000
S42.41 Fracture of lower end of humerus (open)	0.006	0.994	0.000
K86.8 Other specified diseases of pancreas	0.006	0.994	0.000
C17.1 Jejunum	0.006	0.994	0.000
S42.40 Fracture of lower end of humerus (closed)	0.006	0.994	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.006	0.994	0.000
K85.2 Alcohol-induced acute pancreatitis	0.006	0.994	0.000
K85.8 Other acute pancreatitis	0.006	0.994	0.000
C20 Malignant neoplasm of rectum	0.006	0.994	0.000
C15.5 Lower third of oesophagus	0.006	0.994	0.000
C22.9 Liver, unspecified	0.006	0.994	0.000
S42.30 Fracture of shaft of humerus (closed)	0.006	0.994	0.000
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.006	0.994	0.000
C17.2 Ileum	0.006	0.994	0.000
M19.96 Arthrosis, unspecified-Lower leg	0.006	0.994	0.000
S42.31 Fracture of shaft of humerus (open)	0.005	0.994	0.000
K86.9 Disease of pancreas, unspecified	0.006	0.994	0.000
C16.0 Cardia	0.006	0.994	0.000
C24.9 Biliary tract, unspecified	0.005	0.994	0.000
C21.0 Anus, unspecified	0.005	0.994	0.000
C17.8 Overlapping lesion of small intestine	0.005	0.994	0.000
C17.3 Meckel's diverticulum	0.005	0.994	0.000
C24.1 Ampulla of Vater	0.005	0.994	0.000
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.005	0.995	0.000
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.005	0.995	0.000
C17.0 Duodenum	0.005	0.995	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.005	0.995	0.000
C18.6 Descending colon	0.005	0.995	0.000
C24.8 Overlapping lesion of biliary tract	0.005	0.995	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.005	0.995	0.001
C16.2 Body of stomach	0.005	0.995	0.000
C15.3 Upper third of oesophagus	0.005	0.995	0.000
K85.3 Drug-induced acute pancreatitis	0.005	0.995	0.000
K85.0 Idiopathic acute pancreatitis	0.005	0.995	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.005	0.995	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.005	0.995	0.000
C21.2 Cloacogenic zone	0.005	0.995	0.000
C22.7 Other specified carcinomas of liver	0.005	0.995	0.000
C22.4 Other sarcomas of liver	0.005	0.995	0.000
C22.3 Angiosarcoma of liver	0.005	0.995	0.000
C22.2 Hepatoblastoma	0.005	0.995	0.000
K86.3 Pseudocyst of pancreas	0.005	0.995	0.000
C16.3 Pyloric antrum	0.005	0.995	0.000
C15.8 Overlapping lesion of oesophagus	0.005	0.995	0.000
C15.2 Abdominal part of oesophagus	0.005	0.995	0.000
C15.1 Thoracic part of oesophagus	0.005	0.995	0.000
C15.0 Cervical part of oesophagus	0.005	0.995	0.000
C16.8 Overlapping lesion of stomach	0.005	0.995	0.000
C16.6 Greater curvature of stomach, unspecified	0.005	0.995	0.000
C16.4 Pylorus	0.005	0.995	0.000
C16.1 Fundus of stomach	0.005	0.995	0.000
C24.0 Extrahepatic bile duct	0.005	0.995	0.000
K86.1 Other chronic pancreatitis	0.005	0.995	0.000
C17.9 Small intestine, unspecified	0.005	0.995	0.000
C18.0 Caecum	0.005	0.995	0.000
D61.9 Aplastic anaemia, unspecified	0.000	0.995	0.005
C18.8 Overlapping lesion of colon	0.005	0.995	0.000
S42.21 Fracture of upper end of humerus (open)	0.005	0.995	0.000
F02.3 Dementia in Parkinson's disease	0.005	0.995	0.000
C22.1 Intrahepatic bile duct carcinoma	0.005	0.995	0.000
C18.3 Hepatic flexure	0.005	0.995	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.005	0.995	0.000
F02 Dementia in other diseases classified elsewhere	0.005	0.995	0.000
F03 Unspecified dementia	0.004	0.995	0.000
C18.4 Transverse colon	0.004	0.996	0.000
C16.5 Lesser curvature of stomach, unspecified	0.004	0.996	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.000	0.996	0.004
T83.3 Mechanical complication of intra-uterine contraceptive device	0.004	0.996	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.004	0.996	0.000
C21.1 Anal canal	0.004	0.996	0.000
C22.0 Liver cell carcinoma	0.004	0.996	0.000
F01 Vascular dementia	0.004	0.996	0.000
K87.1 Disorders of pancreas in diseases classified elsewhere	0.004	0.996	0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.004	0.996	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.004	0.996	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.004	0.996	0.000
C15.9 Oesophagus, unspecified	0.004	0.996	0.000
C18.7 Sigmoid colon	0.004	0.996	0.000
K85.1 Biliary acute pancreatitis	0.004	0.996	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.004	0.996	0.000
F05.9 Delirium, unspecified	0.004	0.996	0.000
F01.9 Vascular dementia, unspecified	0.004	0.996	0.000
C18.5 Splenic flexure	0.004	0.996	0.000
C18.1 Appendix	0.004	0.996	0.000
I46.9 Cardiac arrest, unspecified	0.000	0.996	0.004
S42.20 Fracture of upper end of humerus (closed)	0.004	0.996	0.000
F07.0 Organic personality disorder	0.004	0.996	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.004	0.996	0.000
Z96.8 Presence of other specified functional implants	0.004	0.996	0.000
C15.4 Middle third of oesophagus	0.003	0.996	0.000
F09 Unspecified organic or symptomatic mental disorder	0.003	0.996	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.003	0.996	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.003	0.996	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.003	0.996	0.000
F02.2 Dementia in Huntington's disease	0.003	0.996	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.003	0.996	0.000
F02.0 Dementia in Pick's disease	0.003	0.996	0.000
D50.8 Other iron deficiency anaemias	0.004	0.996	0.000
K82 Other diseases of gallbladder	0.004	0.996	0.000
C16.9 Stomach, unspecified	0.003	0.997	0.000
K83 Other diseases of biliary tract	0.003	0.997	0.000
R09.0 Asphyxia	0.000	0.997	0.003
F07.2 Postconcussional syndrome	0.003	0.997	0.000
F00 Dementia in Alzheimer's disease	0.003	0.997	0.000
F05.1 Delirium superimposed on dementia	0.003	0.997	0.000
F01.8 Other vascular dementia	0.003	0.997	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.003	0.997	0.000
F01.2 Subcortical vascular dementia	0.003	0.997	0.000
F01.1 Multi-infarct dementia	0.003	0.997	0.000
F01.0 Vascular dementia of acute onset	0.003	0.997	0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.003	0.997	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.003	0.997	0.000
F07.1 Postencephalitic syndrome	0.003	0.997	0.000
F05.0 Delirium not superimposed on dementia, so described	0.003	0.997	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.003	0.997	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.003	0.997	0.000
F06.5 Organic dissociative disorder	0.003	0.997	0.000
F06.4 Organic anxiety disorder	0.003	0.997	0.000
F06.3 Organic mood [affective] disorders	0.003	0.997	0.000
F06.2 Organic delusional [schizophrenia-like] disorder	0.003	0.997	0.000
F06.1 Organic catatonic disorder	0.003	0.997	0.000
F06.0 Organic hallucinosis	0.003	0.997	0.000
F05.8 Other delirium	0.003	0.997	0.000
G24.9 Dystonia, unspecified	0.003	0.997	0.000
M19.98 Arthrosis, unspecified (Other)	0.003	0.997	0.000
N64.5 Other signs and symptoms in breast	0.000	0.997	0.003
N28.9 Disorder of kidney and ureter, unspecified	0.003	0.997	0.000
F06.7 Mild cognitive disorder	0.003	0.997	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.003	0.997	0.000
K82.3 Fistula of gallbladder	0.003	0.997	0.000
K82.0 Obstruction of gallbladder	0.003	0.997	0.000
K82.1 Hydrops of gallbladder	0.003	0.997	0.000
H81.0 Meniere's disease	0.003	0.997	0.000
M19.9 Arthrosis, unspecified	0.003	0.997	0.000
D70 Agranulocytosis	0.000	0.997	0.003
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.003	0.997	0.000
K83.8 Other specified diseases of biliary tract	0.003	0.997	0.000
K83.5 Biliary cyst	0.003	0.997	0.000
K83.4 Spasm of sphincter of Oddi	0.003	0.997	0.000
K83.3 Fistula of bile duct	0.003	0.997	0.000
K83.2 Perforation of bile duct	0.003	0.997	0.000
K82.8 Other specified diseases of gallbladder	0.003	0.997	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.003	0.997	0.000
K83.9 Disease of biliary tract, unspecified	0.003	0.997	0.000
K82.2 Perforation of gallbladder	0.003	0.997	0.000
R04.2 Haemoptysis	0.000	0.997	0.003
K81 Cholecystitis	0.003	0.997	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.002	0.997	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.002	0.997	0.000
Q61.2 Polycystic kidney, adult type	0.003	0.997	0.000
K82.9 Disease of gallbladder, unspecified	0.002	0.997	0.000
R09.1 Pleurisy	0.000	0.997	0.003
M19.97 Arthrosis, unspecified (Ankle and foot)	0.002	0.998	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.002	0.998	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
N64.9 Disorder of breast, unspecified	0.000	0.998	0.002
D61 Other aplastic anaemias	0.000	0.998	0.002
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.002	0.998	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.002	0.998	0.000
T83.2 Mechanical complication of graft of urinary organ	0.002	0.998	0.000
I12.0 Hypertensive renal disease with renal failure	0.002	0.998	0.000
H81.1 Benign paroxysmal vertigo	0.002	0.998	0.000
K81.8 Other cholecystitis	0.002	0.998	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.002	0.998	0.000
A04.5 Campylobacter enteritis	0.000	0.998	0.002
T86.1 Kidney transplant failure and rejection	0.002	0.998	0.000
G91.9 Hydrocephalus, unspecified	0.000	0.998	0.002
H18.5 Hereditary corneal dystrophies	0.000	0.998	0.002
N64 Other disorders of breast	0.000	0.998	0.002
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.002	0.998	0.000
N64.4 Mastodynia	0.000	0.998	0.002
M19.90 Arthrosis, unspecified (Multiple sites)	0.002	0.998	0.000
H81 Disorders of vestibular function	0.002	0.998	0.000
J40 Bronchitis, not specified as acute or chronic	0.002	0.998	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.000	0.998	0.002
M19.92 Arthrosis, unspecified (Upper arm)	0.002	0.998	0.000
H18.4 Corneal degeneration	0.000	0.998	0.002
M19.21 Other secondary arthrosis (Shoulder region)	0.002	0.998	0.000
H18.8 Other specified disorders of cornea	0.000	0.998	0.002
N64.8 Other specified disorders of breast	0.000	0.998	0.002
K65.9 Peritonitis, unspecified	0.002	0.998	0.000
K66.8 Other specified disorders of peritoneum	0.002	0.998	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.002	0.998	0.000
K83.0 Cholangitis	0.002	0.998	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.002	0.998	0.000
H18 Other disorders of cornea	0.000	0.998	0.002
T80 Complications following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
O30.0 Twin pregnancy	0.000	0.998	0.002
F00.9 Dementia in Alzheimer's disease, unspecified	0.002	0.998	0.000
H18.6 Keratoconus	0.000	0.998	0.002
K81.9 Cholecystitis, unspecified	0.002	0.998	0.000
Z73.3 Stress, not elsewhere classified	0.002	0.998	0.000
Z99.2 Dependence on renal dialysis	0.002	0.998	0.000
D61.8 Other specified aplastic anaemias	0.000	0.998	0.002
D61.3 Idiopathic aplastic anaemia	0.000	0.998	0.002
D61.2 Aplastic anaemia due to other external agents	0.000	0.998	0.002
D61.1 Drug-induced aplastic anaemia	0.000	0.998	0.002
D61.0 Constitutional aplastic anaemia	0.000	0.998	0.002
H81.3 Other peripheral vertigo	0.002	0.998	0.000
M19.2 Other secondary arthrosis	0.002	0.998	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.002	0.998	0.000
T86 Failure and rejection of transplanted organs and tissues	0.002	0.998	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.002	0.998	0.000
M19.27 Other secondary arthrosis (Ankle and foot)	0.002	0.998	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.002	0.998	0.000
Z96.0 Presence of urogenital implants	0.002	0.998	0.000
I05.9 Mitral valve disease, unspecified	0.000	0.998	0.002
N64.3 Galactorrhoea not associated with childbirth	0.000	0.998	0.002
N64.2 Atrophy of breast	0.000	0.998	0.002
N64.0 Fissure and fistula of nipple	0.000	0.998	0.002
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.002	0.998	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.002	0.998	0.000
H81.8 Other disorders of vestibular function	0.002	0.998	0.000
H81.4 Vertigo of central origin	0.002	0.998	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
H18.2 Other corneal oedema	0.000	0.998	0.002
H81.9 Disorder of vestibular function, unspecified	0.002	0.998	0.000
R09.2 Respiratory arrest	0.000	0.998	0.002
M19.91 Arthrosis, unspecified (Shoulder region)	0.002	0.998	0.000
K50.8 Other Crohn's disease	0.002	0.998	0.000
H18.7 Other corneal deformities	0.000	0.998	0.002
H18.3 Changes in corneal membranes	0.000	0.998	0.002
H18.1 Bullous keratopathy	0.000	0.998	0.002
H18.0 Corneal pigmentations and deposits	0.000	0.998	0.002
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
T80.6 Other serum reactions	0.002	0.998	0.000
T80.5 Anaphylactic shock due to serum	0.002	0.998	0.000
T80.4 Rh incompatibility reaction	0.002	0.998	0.000
T80.3 ABO incompatibility reaction	0.002	0.998	0.000
T80.2 Infections following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.002	0.998	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.002	0.998	0.000
K81.0 Acute cholecystitis	0.002	0.998	0.000
M19.29 Other secondary arthrosis (Site unspecified)	0.002	0.998	0.000
M19.28 Other secondary arthrosis (Other)	0.002	0.998	0.000
M19.26 Other secondary arthrosis of other joints-Lower leg	0.002	0.998	0.000
M19.25 Other secondary arthrosis (Pelvic region and thigh)	0.002	0.998	0.000
M19.24 Other secondary arthrosis (Hand)	0.002	0.998	0.000
M19.23 Other secondary arthrosis (Forearm)	0.002	0.998	0.000
M19.22 Other secondary arthrosis (Upper arm)	0.002	0.998	0.000
M19.20 Other secondary arthrosis (Multiple sites)	0.002	0.998	0.000
K83.1 Obstruction of bile duct	0.002	0.998	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.002	0.998	0.000
G96.0 Cerebrospinal fluid leak	0.002	0.998	0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.001	0.998	0.000
T86.4 Liver transplant failure and rejection	0.001	0.998	0.000
T86.3 Heart-lung transplant failure and rejection	0.001	0.998	0.000
T86.2 Heart transplant failure and rejection	0.001	0.998	0.000
M19 Other arthrosis	0.002	0.998	0.000
T87 Complications peculiar to reattachment and amputation	0.002	0.998	0.000
K82.4 Cholesterolosis of gallbladder	0.002	0.998	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.000	0.998	0.002
D50 Iron deficiency anaemia	0.002	0.998	0.000
Z95.0 Presence of cardiac pacemaker	0.000	0.998	0.002
M25.46 Effusion of joint (Lower leg)	0.002	0.998	0.000
F50.0 Anorexia nervosa	0.002	0.998	0.000
Z96.7 Presence of other bone and tendon implants	0.002	0.998	0.000
I05.0 Mitral stenosis	0.000	0.998	0.002
T85.4 Mechanical complication of breast prosthesis and implant	0.002	0.998	0.000
N90.4 Leukoplakia of vulva	0.000	0.998	0.002
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.002	0.998	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.001	0.998	0.000
A63.0 Anogenital (venereal) warts	0.000	0.998	0.002
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.001	0.998	0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.002	0.998	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.001	0.998	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.001	0.998	0.000
T87.3 Neuroma of amputation stump	0.001	0.998	0.000
H81.2 Vestibular neuronitis	0.001	0.998	0.000
L03.0 Cellulitis of finger and toe	0.000	0.998	0.001
D50.9 Iron deficiency anaemia, unspecified	0.001	0.999	0.000
H18.9 Disorder of cornea, unspecified	0.000	0.999	0.001
M19.8 Other specified arthrosis	0.001	0.999	0.000
T87.5 Necrosis of amputation stump	0.001	0.999	0.000
T87.2 Complications of other reattached body part	0.001	0.999	0.000
T87.1 Complications of reattached (part of) lower extremity	0.001	0.999	0.000
T87.0 Complications of reattached (part of) upper extremity	0.001	0.999	0.000
D50.1 Sideropenic dysphagia	0.001	0.999	0.000
N73.9 Female pelvic inflammatory disease, unspecified	0.001	0.999	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.001	0.999	0.000
Z96 Presence of other functional implants	0.001	0.999	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.001	0.999	0.000
I12 Hypertensive renal disease	0.001	0.999	0.000
D10.3 Other and unspecified parts of mouth	0.001	0.999	0.000
H65.2 Chronic serous otitis media	0.001	0.999	0.000
Z96.9 Presence of functional implant, unspecified	0.001	0.999	0.000
Q61 Cystic kidney disease	0.001	0.999	0.000
L60.8 Other nail disorders	0.000	0.999	0.001
T86.0 Bone-marrow transplant rejection	0.001	0.999	0.000
I05 Rheumatic mitral valve diseases	0.000	0.999	0.001
F50 Eating disorders	0.001	0.999	0.000
M19.94 Arthrosis, unspecified (Hand)	0.001	0.999	0.000
G31.8 Other specified degenerative diseases of nervous system	0.000	0.999	0.001
I05.1 Rheumatic mitral insufficiency	0.000	0.999	0.001
Z96.2 Presence of otological and audiological implants	0.001	0.999	0.000
Z34 Supervision of normal pregnancy	0.000	0.999	0.001
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
H93.1 Tinnitus	0.000	0.999	0.001
N73.6 Female pelvic peritoneal adhesions	0.001	0.999	0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.000	0.999	0.001
Z34.0 Supervision of normal first pregnancy	0.000	0.999	0.001
Z49.1 Extracorporeal dialysis	0.001	0.999	0.000
I46 Cardiac arrest	0.000	0.999	0.001
M19.89 Other specified arthrosis (Site unspecified)	0.001	0.999	0.000
M19.88 Other specified arthrosis (Other)	0.001	0.999	0.000
M19.87 Other specified arthrosis (Ankle and foot)	0.001	0.999	0.000
M19.86 Other specified arthrosis (Lower leg)	0.001	0.999	0.000
M19.85 Other specified arthrosis (Pelvic region and thigh)	0.001	0.999	0.000
M19.84 Other specified arthrosis (Hand)	0.001	0.999	0.000
M19.83 Other specified arthrosis (Forearm)	0.001	0.999	0.000
M19.82 Other specified arthrosis (Upper arm)	0.001	0.999	0.000
M19.81 Other specified arthrosis (Shoulder region)	0.001	0.999	0.000
M19.80 Other specified arthrosis (Multiple sites)	0.001	0.999	0.000
F50.9 Eating disorder, unspecified	0.001	0.999	0.000
M13.0 Polyarthritis, unspecified	0.001	0.999	0.000
Q61.3 Polycystic kidney, unspecified	0.001	0.999	0.000
T87.4 Infection of amputation stump	0.001	0.999	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.999	0.001
I12.9 Hypertensive renal disease without renal failure	0.001	0.999	0.000
R09.3 Abnormal sputum	0.000	0.999	0.001
Z96.5 Presence of tooth-root and mandibular implants	0.001	0.999	0.000
Z96.4 Presence of endocrine implants	0.001	0.999	0.000
Z96.3 Presence of artificial larynx	0.001	0.999	0.000
T85.2 Mechanical complication of intraocular lens	0.001	0.999	0.000
L30.9 Dermatitis, unspecified	0.001	0.999	0.000
Q61.9 Cystic kidney disease, unspecified	0.001	0.999	0.000
Q61.8 Other cystic kidney diseases	0.001	0.999	0.000
Q61.5 Medullary cystic kidney	0.001	0.999	0.000
Q61.4 Renal dysplasia	0.001	0.999	0.000
Q61.1 Polycystic kidney, infantile type	0.001	0.999	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.001	0.999	0.001
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.001	0.999	0.000
F81 Specific developmental disorders of scholastic skills	0.001	0.999	0.000
C18.9 Colon, unspecified	0.001	0.999	0.000
I05.8 Other mitral valve diseases	0.000	0.999	0.001
I05.2 Mitral stenosis with insufficiency	0.000	0.999	0.001
M19.06 Primary arthrosis of other joints-Lower leg	0.001	0.999	0.000
F50.8 Other eating disorders	0.001	0.999	0.000
F50.5 Vomiting associated with other psychological disturbances	0.001	0.999	0.000
F50.4 Overeating associated with other psychological disturbances	0.001	0.999	0.000
F50.3 Atypical bulimia nervosa	0.001	0.999	0.000
F50.2 Bulimia nervosa	0.001	0.999	0.000
F50.1 Atypical anorexia nervosa	0.001	0.999	0.000
K12.3 Oral mucositis (ulcerative)	0.000	0.999	0.001
M19.1 Posttraumatic arthrosis of other joints	0.001	0.999	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.001	0.999	0.000
T87.6 Other and unspecified complications of amputation stump	0.001	0.999	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.001	0.999	0.000
M13.08 Polyarthritis, unspecified (Other)	0.001	0.999	0.000
M13.07 Polyarthritis, unspecified (Ankle and foot)	0.001	0.999	0.000
M13.06 Polyarthritis, unspecified (Lower leg)	0.001	0.999	0.000
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M13.04 Polyarthritis, unspecified (Hand)	0.001	0.999	0.000
M13.03 Polyarthritis, unspecified (Forearm)	0.001	0.999	0.000
M13.02 Polyarthritis, unspecified (Upper arm)	0.001	0.999	0.000
M13.01 Polyarthritis, unspecified (Shoulder region)	0.001	0.999	0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.000	0.999	0.001
I46.1 Sudden cardiac death, so described	0.000	0.999	0.001
M19.0 Primary arthrosis of other joints	0.001	0.999	0.000
N93.8 Other specified abnormal uterine and vaginal bleeding	0.001	0.999	0.000
O32.1 Maternal care for breech presentation	0.001	0.999	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.001	0.999	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.999	0.001
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M94.88 Other specified disorders of cartilage (Other)	0.000	0.999	0.001
B18.2 Chronic viral hepatitis C	0.001	0.999	0.000
J39.2 Other diseases of pharynx	0.000	0.999	0.001
M24.8 Other specific joint derangements, not elsewhere classified	0.001	0.999	0.000
G24 Dystonia	0.001	0.999	0.000
F81.8 Other developmental disorders of scholastic skills	0.001	0.999	0.000
F81.3 Mixed disorder of scholastic skills	0.001	0.999	0.000
F81.2 Specific disorder of arithmetical skills	0.001	0.999	0.000
F81.1 Specific spelling disorder	0.001	0.999	0.000
F81.0 Specific reading disorder	0.001	0.999	0.000
N64.1 Fat necrosis of breast	0.000	0.999	0.001
M19.04 Primary arthrosis of other joints (Hand)	0.001	0.999	0.000
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.001	0.999	0.000
M19.18 Post-traumatic arthrosis of other joints (Other)	0.001	0.999	0.000
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.001	0.999	0.000
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.001	0.999	0.000
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.001	0.999	0.000
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.001	0.999	0.000
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.001	0.999	0.000
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.001	0.999	0.000
B25.9 Cytomegaloviral disease, unspecified	0.000	0.999	0.001
D75.2 Essential thrombocytosis	0.001	0.999	0.000
D75.1 Secondary polycythaemia	0.001	0.999	0.000
K56.5 Intestinal adhesions [bands] with obstruction	0.001	0.999	0.000
T88.9 Complication of surgical and medical care, unspecified	0.001	0.999	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.001	0.999	0.000
T88.2 Shock due to anaesthesia	0.001	0.999	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.001	0.999	0.000
T88.0 Infection following immunisation	0.001	0.999	0.000
M19.08 Primary arthrosis of other joints (Other)	0.001	0.999	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.001	0.999	0.000
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.001	0.999	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.999	0.001
C43.5 Malignant melanoma of trunk	0.001	0.999	0.000
N18.5 Chronic kidney disease, stage 5	0.001	0.999	0.000
Z73.6 Limitation of activities due to disability	0.001	0.999	0.000
Z73 Problems related to life-management difficulty	0.001	0.999	0.000
M13.09 Polyarthritis, unspecified (Site unspecified)	0.001	0.999	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.001	0.999	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.001	0.999	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.001	0.999	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.001	0.999	0.000
F33.9 Recurrent depressive disorder, unspecified	0.000	0.999	0.001
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.000	0.999	0.001
Q05.9 Spina bifida, unspecified	0.001	0.999	0.000
Z90.4 Acquired absence of other parts of digestive tract	0.001	0.999	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.001	0.999	0.000
G24.8 Other dystonia	0.001	0.999	0.000
G24.4 Idiopathic orofacial dystonia	0.001	0.999	0.000
G24.3 Spasmodic torticollis	0.001	0.999	0.000
G24.2 Idiopathic nonfamilial dystonia	0.001	0.999	0.000
G24.1 Idiopathic familial dystonia	0.001	0.999	0.000
G24.0 Drug-induced dystonia	0.001	0.999	0.000
M15.1 Heberden's nodes (with arthropathy)	0.001	0.999	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.001	0.999	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.001	0.999	0.000
S00.1 Contusion of eyelid and periocular area	0.000	0.999	0.001
Z73.9 Problem related to life-management difficulty, unspecified	0.001	0.999	0.000
S40-S49 Injuries to the shoulder and upper arm	0.001	0.999	0.000
F80.1 Expressive language disorder	0.001	0.999	0.000
I77.8 Other specified disorders of arteries and arterioles	0.000	0.999	0.001
R30.0 Dysuria	0.000	0.999	0.001
S43.1 Dislocation of acromioclavicular joint	0.000	0.999	0.001
M19.00 Primary arthrosis of other joints (Multiple sites)	0.001	0.999	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M65.34 Trigger finger-Hand	0.000	0.999	0.001
M94.86 Other specified disorders of cartilage (Lower leg)	0.000	0.999	0.001
F20.9 Schizophrenia, unspecified	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations