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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs34328549
log Bayes Factor = 11.7329
Chromosome 19   position 7,253,184  (GRCh37) Explore rs34328549 on Ensembl!
Variant rs34328549 is part of Cluster X0011

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I10 Essential (primary) hypertension
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.087 0.913
I20.0 Unstable angina
0.000 0.140 0.860
Chapter IX Diseases of the circulatory system
0.000 0.146 0.854
I20 Angina pectoris
0.000 0.151 0.849
I20-I25 Ischaemic heart diseases
0.000 0.157 0.843
I35.0 Aortic (valve) stenosis
0.000 0.185 0.815
I05-I09 Chronic rheumatic heart diseases
0.000 0.189 0.811
I35 Nonrheumatic aortic valve disorders
0.000 0.195 0.805
I22 Subsequent myocardial infarction
0.000 0.235 0.765
I30-I52 Other forms of heart disease
0.000 0.236 0.764
I08 Multiple valve diseases
0.000 0.250 0.750
I35.1 Aortic (valve) insufficiency
0.000 0.271 0.729
I31 Other diseases of pericardium
0.000 0.274 0.726
I11 Hypertensive heart disease
0.000 0.282 0.718
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.291 0.709
I05 Rheumatic mitral valve diseases
0.000 0.296 0.704
I31.3 Pericardial effusion (noninflammatory)
0.000 0.312 0.688
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.313 0.687
I08.0 Disorders of both mitral and aortic valves
0.000 0.316 0.684
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.318 0.682
I20.1 Angina pectoris with documented spasm
0.000 0.318 0.682
I20.8 Other forms of angina pectoris
0.000 0.335 0.665
I13 Hypertensive heart and renal disease
0.000 0.345 0.655
I05.9 Mitral valve disease, unspecified
0.000 0.352 0.648
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.354 0.646
I08.8 Other multiple valve diseases
0.000 0.360 0.640
I71 Aortic aneurysm and dissection
0.000 0.372 0.628
I07 Rheumatic tricuspid valve diseases
0.000 0.386 0.614
I00-I02 Acute rheumatic fever
0.000 0.388 0.612
I30 Acute pericarditis
0.000 0.389 0.611
I15 Secondary hypertension
0.000 0.389 0.611
I12 Hypertensive renal disease
0.000 0.390 0.610
I23 Certain current complications following acute myocardial infarction
0.000 0.405 0.594
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.411 0.589
I22.8 Subsequent myocardial infarction of other sites
0.000 0.412 0.588
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.417 0.583
I31.9 Disease of pericardium, unspecified
0.000 0.418 0.582
I71.0 Dissection of aorta [any part]
0.000 0.420 0.580
I27 Other pulmonary heart diseases
0.000 0.425 0.575
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.426 0.574
I09 Other rheumatic heart diseases
0.000 0.427 0.573
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.429 0.571
I36 Nonrheumatic tricuspid valve disorders
0.000 0.435 0.565
I35.8 Other aortic valve disorders
0.000 0.440 0.560
I45 Other conduction disorders
0.000 0.447 0.553
I52 Other heart disorders in diseases classified elsewhere
0.000 0.452 0.548
I48 Atrial fibrillation and flutter
0.000 0.452 0.548
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.452 0.548
I41 Myocarditis in diseases classified elsewhere
0.000 0.452 0.548
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.452 0.548
I32 Pericarditis in diseases classified elsewhere
0.000 0.452 0.548
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.452 0.548
I27.0 Primary pulmonary hypertension
0.000 0.458 0.542
I46 Cardiac arrest
0.000 0.460 0.540
I35.9 Aortic valve disorder, unspecified
0.000 0.461 0.539
I05.1 Rheumatic mitral insufficiency
0.000 0.462 0.538
I08.9 Multiple valve disease, unspecified
0.000 0.462 0.538
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.468 0.532
I06 Rheumatic aortic valve diseases
0.000 0.473 0.526
I50 Heart failure
0.000 0.475 0.525
I33 Acute and subacute endocarditis
0.000 0.477 0.523
I31.8 Other specified diseases of pericardium
0.000 0.479 0.521
I31.2 Haemopericardium, not elsewhere classified
0.000 0.479 0.521
I31.1 Chronic constrictive pericarditis
0.000 0.479 0.521
I31.0 Chronic adhesive pericarditis
0.000 0.479 0.521
I72 Other aneurysm
0.000 0.488 0.512
I45.6 Preexcitation syndrome
0.000 0.491 0.509
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.493 0.507
I30.1 Infective pericarditis
0.000 0.494 0.506
I05.8 Other mitral valve diseases
0.000 0.495 0.505
I40 Acute myocarditis
0.000 0.502 0.498
I37 Pulmonary valve disorders
0.000 0.504 0.495
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.507 0.493
I74 Arterial embolism and thrombosis
0.000 0.512 0.488
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.516 0.484
I50.0 Congestive heart failure
0.000 0.516 0.484
I45.5 Other specified heart block
0.000 0.526 0.474
I07.1 Tricuspid insufficiency
0.000 0.527 0.473
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.530 0.469
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.530 0.469
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.530 0.469
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.530 0.469
I05.2 Mitral stenosis with insufficiency
0.000 0.543 0.456
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.549 0.451
I12.0 Hypertensive renal disease with renal failure
0.000 0.549 0.451
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.549 0.451
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.549 0.451
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.549 0.451
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.549 0.451
I27.9 Pulmonary heart disease, unspecified
0.000 0.550 0.450
I77 Other disorders of arteries and arterioles
0.000 0.552 0.448
I28 Other diseases of pulmonary vessels
0.000 0.553 0.447
I72.0 Aneurysm of carotid artery
0.000 0.553 0.447
I05.0 Mitral stenosis
0.000 0.558 0.441
I07.9 Tricuspid valve disease, unspecified
0.000 0.560 0.440
I07.8 Other tricuspid valve diseases
0.000 0.560 0.440
I07.2 Tricuspid stenosis with insufficiency
0.000 0.560 0.440
I07.0 Tricuspid stenosis
0.000 0.560 0.440
I02 Rheumatic chorea
0.000 0.561 0.439
I01 Rheumatic fever with heart involvement
0.000 0.561 0.439
I00 Rheumatic fever without mention of heart involvement
0.000 0.561 0.439
I30.8 Other forms of acute pericarditis
0.000 0.562 0.438
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.562 0.438
I15.9 Seconday hypertension, unspecified
0.000 0.562 0.438
I15.8 Other secondary hypertension
0.000 0.562 0.438
I15.2 Hypertension secondary to endocrine disorders
0.000 0.562 0.438
I15.0 Renovascular hypertension
0.000 0.562 0.438
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.563 0.437
I72.3 Aneurysm of iliac artery
0.000 0.566 0.434
I30.9 Acute pericarditis, unspecified
0.000 0.569 0.431
I24 Other acute ischaemic heart diseases
0.000 0.571 0.429
I46.9 Cardiac arrest, unspecified
0.000 0.571 0.429
I45.4 Nonspecific intraventricular block
0.000 0.572 0.428
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.574 0.426
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.574 0.426
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.574 0.426
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.574 0.426
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.574 0.426
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.574 0.426
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.574 0.426
I27.8 Other specified pulmonary heart diseases
0.000 0.578 0.422
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.578 0.422
I70 Atherosclerosis
0.000 0.581 0.419
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.582 0.418
I23.8 Other current complications following acute myocardial infarction
0.000 0.584 0.416
I78 Diseases of capillaries
0.000 0.585 0.415
I27.1 Kyphoscoliotic heart disease
0.000 0.588 0.412
I09.8 Other specified rheumatic heart diseases
0.000 0.589 0.411
I09.2 Chronic rheumatic pericarditis
0.000 0.589 0.411
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.589 0.411
I09.0 Rheumatic myocarditis
0.000 0.589 0.411
I45.3 Trifascicular block
0.000 0.594 0.406
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.595 0.405
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.595 0.405
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.595 0.405
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.595 0.405
I09.9 Rheumatic heart disease, unspecified
0.000 0.598 0.402
I45.0 Right fascicular block
0.000 0.603 0.397
I15.1 Hypertension secondary to other renal disorders
0.000 0.606 0.393
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.607 0.393
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.607 0.393
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.607 0.393
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.607 0.393
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.607 0.393
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.607 0.393
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.607 0.393
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.607 0.393
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.607 0.393
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.607 0.393
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.607 0.393
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.607 0.393
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.607 0.393
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.607 0.393
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.607 0.393
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.607 0.393
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.607 0.393
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.607 0.393
I48.4 Atypical atrial flutter
0.000 0.607 0.393
I48.3 Typical atrial flutter
0.000 0.607 0.393
I48.2 Chronic atrial fibrillation
0.000 0.607 0.393
I48.1 Persistent atrial fibrillation
0.000 0.607 0.393
I48.0 Paroxysmal atrial fibrillation
0.000 0.607 0.393
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.607 0.393
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.607 0.393
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.607 0.393
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.607 0.393
I79.1 Aortitis in diseases classified elsewhere
0.000 0.607 0.393
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.607 0.393
I46.1 Sudden cardiac death, so described
0.000 0.612 0.388
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.622 0.377
I06.8 Other rheumatic aortic valve diseases
0.000 0.622 0.377
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.622 0.377
I06.1 Rheumatic aortic insufficiency
0.000 0.622 0.377
I73 Other peripheral vascular diseases
0.000 0.624 0.376
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.625 0.375
I33.9 Acute endocarditis, unspecified
0.000 0.625 0.375
I12.9 Hypertensive renal disease without renal failure
0.000 0.627 0.373
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.633 0.367
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.633 0.367
I72.2 Aneurysm of renal artery
0.000 0.633 0.367
I72.1 Aneurysm of artery of upper extremity
0.000 0.633 0.367
I72.9 Aneurysm of unspecified site
0.000 0.633 0.367
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.641 0.359
I45.9 Conduction disorder, unspecified
0.000 0.642 0.358
I40.8 Other acute myocarditis
0.000 0.643 0.357
I40.1 Isolated myocarditis
0.000 0.643 0.357
I40.0 Infective myocarditis
0.000 0.643 0.357
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.643 0.357
I37.9 Pulmonary valve disorder, unspecified
0.000 0.644 0.355
I37.8 Other pulmonary valve disorders
0.000 0.644 0.355
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.644 0.355
I37.0 Pulmonary valve stenosis
0.000 0.644 0.355
I33.0 Acute and subacute infective endocarditis
0.000 0.650 0.350
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.650 0.350
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.650 0.350
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.650 0.350
I77.8 Other specified disorders of arteries and arterioles
0.000 0.657 0.343
I77.0 Arteriovenous fistula, acquired
0.000 0.659 0.341
I74.8 Embolism and thrombosis of other arteries
0.000 0.665 0.334
I77.6 Arteritis, unspecified
0.000 0.672 0.328
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.673 0.327
I06.0 Rheumatic aortic stenosis
0.000 0.677 0.323
I77.5 Necrosis of artery
0.000 0.679 0.321
I77.4 Coeliac artery compression syndrome
0.000 0.679 0.321
I77.3 Arterial fibromuscular dysplasia
0.000 0.679 0.321
I77.2 Rupture of artery
0.000 0.679 0.321
I46.0 Cardiac arrest with successful resuscitation
0.000 0.679 0.321
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.679 0.320
I28.1 Aneurysm of pulmonary artery
0.000 0.679 0.320
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.679 0.320
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.685 0.315
I01.8 Other acute rheumatic heart disease
0.000 0.685 0.315
I01.2 Acute rheumatic myocarditis
0.000 0.685 0.315
I01.1 Acute rheumatic endocarditis
0.000 0.685 0.315
I01.0 Acute rheumatic pericarditis
0.000 0.685 0.315
I02.9 Rheumatic chorea without heart involvement
0.000 0.685 0.315
I02.0 Rheumatic chorea with heart involvement
0.000 0.685 0.315
I45.2 Bifascicular block
0.000 0.685 0.315
I74.5 Embolism and thrombosis of iliac artery
0.000 0.687 0.313
I24.1 Dressler's syndrome
0.000 0.692 0.308
I40.9 Acute myocarditis, unspecified
0.000 0.692 0.308
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.692 0.308
I28.8 Other specified diseases of pulmonary vessels
0.000 0.696 0.304
I37.1 Pulmonary valve insufficiency
0.000 0.697 0.303
I24.8 Other forms of acute ischaemic heart disease
0.000 0.698 0.302
I70.9 Generalised and unspecified atherosclerosis
0.000 0.699 0.301
I70.8 Atherosclerosis of other arteries
0.000 0.699 0.301
I26 Pulmonary embolism
0.000 0.702 0.298
I78.9 Disease of capillaries, unspecified
0.000 0.702 0.297
I77.1 Stricture of artery
0.000 0.703 0.297
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.716 0.284
I70.1 Atherosclerosis of renal artery
0.000 0.716 0.283
I78.8 Other diseases of capillaries
0.000 0.717 0.283
I70.0 Atherosclerosis of aorta
0.000 0.718 0.282
I73.8 Other specified peripheral vascular diseases
0.000 0.719 0.281
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.723 0.277
I72.8 Aneurysm of other specified arteries
0.000 0.725 0.274
I50.1 Left ventricular failure
0.000 0.728 0.272
I45.8 Other specified conduction disorders
0.000 0.728 0.271
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.730 0.270
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.738 0.262
I51 Complications and ill-defined descriptions of heart disease
0.000 0.739 0.261
I44 Atrioventricular and left bundle-branch block
0.000 0.756 0.244
I20.9 Angina pectoris, unspecified
0.000 0.758 0.242
I34 Nonrheumatic mitral valve disorders
0.000 0.762 0.238
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.764 0.235
C18.9 Colon, unspecified
0.230 0.770 0.000
I27.2 Other secondary pulmonary hypertension
0.000 0.772 0.227
I51.4 Myocarditis, unspecified
0.000 0.773 0.227
I73.9 Peripheral vascular disease, unspecified
0.000 0.774 0.226
C18 Malignant neoplasm of colon
0.224 0.776 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.778 0.222
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.784 0.216
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.784 0.216
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.784 0.216
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.784 0.216
I44.6 Other and unspecified fascicular block
0.000 0.785 0.215
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.786 0.214
C18.3 Hepatic flexure
0.212 0.788 0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.791 0.209
I72.4 Aneurysm of artery of lower extremity
0.001 0.793 0.207
Q21.1 Atrial septal defect
0.204 0.796 0.000
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.796 0.203
I51.9 Heart disease, unspecified
0.000 0.797 0.203
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.797 0.202
I73.0 Raynaud's syndrome
0.000 0.797 0.202
Q21 Congenital malformations of cardiac septa
0.198 0.802 0.000
C18.7 Sigmoid colon
0.196 0.804 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.807 0.192
C15-C26 Malignant neoplasms of digestive organs
0.188 0.812 0.000
I51.5 Myocardial degeneration
0.000 0.812 0.188
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.812 0.188
C18.0 Caecum
0.187 0.813 0.000
I78.1 Naevus, nonneoplastic
0.000 0.813 0.186
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.814 0.186
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.815 0.185
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.815 0.184
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.816 0.184
Q20-Q28 Congenital malformations of the circulatory system
0.183 0.817 0.000
Q21.0 Ventricular septal defect
0.182 0.818 0.000
I44.2 Atrioventricular block, complete
0.000 0.819 0.181
I47 Paroxysmal tachycardia
0.000 0.822 0.178
I44.5 Left posterior fascicular block
0.000 0.825 0.175
I97.1 Other functional disturbances following cardiac surgery
0.000 0.825 0.175
I51.0 Cardiac septal defect, acquired
0.000 0.825 0.175
C17 Malignant neoplasm of small intestine
0.175 0.825 0.000
I44.3 Other and unspecified atrioventricular block
0.000 0.828 0.172
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.829 0.171
I51.6 Cardiovascular disease, unspecified
0.000 0.829 0.171
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.830 0.170
C26 Malignant neoplasm of other and ill-defined digestive organs
0.169 0.831 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.831 0.169
I99 Other and unspecified disorders of circulatory system
0.000 0.832 0.167
C15 Malignant neoplasm of oesophagus
0.167 0.833 0.000
I44.1 Atrioventricular block, second degree
0.000 0.834 0.166
I50.9 Heart failure, unspecified
0.000 0.835 0.165
C18.8 Overlapping lesion of colon
0.164 0.836 0.000
Q23 Congenital malformations of aortic and mitral valves
0.164 0.836 0.000
C18.1 Appendix
0.163 0.836 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.837 0.163
C17.0 Duodenum
0.163 0.837 0.000
I44.4 Left anterior fascicular block
0.000 0.839 0.161
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.840 0.159
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.841 0.159
I97.0 Postcardiotomy syndrome
0.000 0.841 0.159
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.841 0.158
C18.2 Ascending colon
0.158 0.842 0.000
C26.0 Intestinal tract, part unspecified
0.156 0.844 0.000
Q24 Other congenital malformations of heart
0.155 0.845 0.000
C15.9 Oesophagus, unspecified
0.154 0.846 0.000
I45.1 Other and unspecified right bundle-branch block
0.000 0.849 0.151
Q23.1 Congenital insufficiency of aortic valve
0.151 0.849 0.000
C25 Malignant neoplasm of pancreas
0.148 0.852 0.000
C16 Malignant neoplasm of stomach
0.144 0.856 0.000
Q21.9 Congenital malformation of cardiac septum, unspecified
0.142 0.858 0.000
Q21.8 Other congenital malformations of cardiac septa
0.142 0.858 0.000
Q21.4 Aortopulmonary septal defect
0.142 0.858 0.000
Q21.3 Tetralogy of Fallot
0.142 0.858 0.000
Q21.2 Atrioventricular septal defect
0.142 0.858 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.861 0.139
Q25 Congenital malformations of great arteries
0.138 0.861 0.000
I47.0 Reentry ventricular arrhythmia
0.000 0.863 0.137
Q28 Other congenital malformations of circulatory system
0.135 0.864 0.000
I95 Hypotension
0.000 0.865 0.135
C18.6 Descending colon
0.135 0.865 0.000
C23 Malignant neoplasm of gallbladder
0.134 0.866 0.000
Q24.9 Congenital malformation of the heart, unspecified
0.133 0.867 0.000
C15.3 Upper third of oesophagus
0.133 0.867 0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.867 0.132
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.867 0.132
I98.0 Cardiovascular syphilis
0.000 0.867 0.132
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.132 0.868 0.000
C17.2 Ileum
0.132 0.868 0.000
Q26 Congenital malformations of great veins
0.131 0.869 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.131 0.869 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.131 0.869 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.131 0.869 0.000
C18.4 Transverse colon
0.130 0.870 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.870 0.130
C17.9 Small intestine, unspecified
0.129 0.871 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.127 0.873 0.000
Q50-Q56 Congenital malformations of genital organs
0.126 0.874 0.000
C15.4 Middle third of oesophagus
0.125 0.875 0.000
C17.8 Overlapping lesion of small intestine
0.125 0.875 0.000
C17.3 Meckel's diverticulum
0.125 0.875 0.000
C17.1 Jejunum
0.125 0.875 0.000
C18.5 Splenic flexure
0.123 0.877 0.000
C26.9 Ill-defined sites within the digestive system
0.122 0.878 0.000
C26.8 Overlapping lesion of digestive system
0.121 0.878 0.000
C26.1 Spleen
0.121 0.878 0.000
C25.7 Other parts of pancreas
0.121 0.879 0.000
C15.8 Overlapping lesion of oesophagus
0.120 0.880 0.000
C15.2 Abdominal part of oesophagus
0.120 0.880 0.000
C15.1 Thoracic part of oesophagus
0.120 0.880 0.000
C15.0 Cervical part of oesophagus
0.120 0.880 0.000
Q23.0 Congenital stenosis of aortic valve
0.119 0.880 0.000
Q51 Congenital malformations of uterus and cervix
0.119 0.881 0.000
I95.8 Other hypotension
0.000 0.881 0.119
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.118 0.881 0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified
0.118 0.882 0.000
Q23.8 Other congenital malformations of aortic and mitral valves
0.118 0.882 0.000
Q23.4 Hypoplastic left heart syndrome
0.118 0.882 0.000
Q23.3 Congenital mitral insufficiency
0.118 0.882 0.000
Q23.2 Congenital mitral stenosis
0.118 0.882 0.000
Q24.8 Other specified congenital malformations of heart
0.117 0.883 0.000
C25.1 Body of pancreas
0.116 0.884 0.000
C16.4 Pylorus
0.115 0.885 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.114 0.886 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.887 0.112
C25.9 Pancreas, unspecified
0.112 0.888 0.000
Q24.6 Congenital heart block
0.111 0.888 0.000
Q24.5 Malformation of coronary vessels
0.111 0.888 0.000
Q24.4 Congenital subaortic stenosis
0.111 0.888 0.000
Q24.3 Pulmonary infundibular stenosis
0.111 0.888 0.000
Q24.2 Cor triatriatum
0.111 0.888 0.000
Q24.1 Levocardia
0.111 0.888 0.000
Q24.0 Dextrocardia
0.111 0.888 0.000
Q51.3 Bicornate uterus
0.111 0.889 0.000
C16.2 Body of stomach
0.109 0.891 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.108 0.892 0.000
C21 Malignant neoplasm of anus and anal canal
0.108 0.892 0.000
C16.3 Pyloric antrum
0.107 0.893 0.000
C16.9 Stomach, unspecified
0.107 0.893 0.000
Q25.1 Coarctation of aorta
0.107 0.893 0.000
C25.8 Overlapping lesion of pancreas
0.106 0.894 0.000
C25.4 Endocrine pancreas
0.106 0.894 0.000
C25.3 Pancreatic duct
0.106 0.894 0.000
C16.6 Greater curvature of stomach, unspecified
0.106 0.894 0.000
Q27 Other congenital malformations of peripheral vascular system
0.105 0.894 0.000
Q66 Congenital deformities of feet
0.104 0.896 0.000
C16.8 Overlapping lesion of stomach
0.103 0.897 0.000
C16.1 Fundus of stomach
0.103 0.897 0.000
I51.8 Other ill-defined heart diseases
0.000 0.898 0.102
Q28.2 Arteriovenous malformation of cerebral vessels
0.102 0.898 0.000
I38 Endocarditis, valve unspecified
0.004 0.899 0.097
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.899 0.100
Q51.2 Other doubling of uterus
0.100 0.899 0.000
Q25.9 Congenital malformation of great arteries, unspecified
0.099 0.900 0.000
Q25.8 Other congenital malformations of great arteries
0.099 0.900 0.000
Q25.7 Other congenital malformations of pulmonary artery
0.099 0.900 0.000
Q25.6 Stenosis of pulmonary artery
0.099 0.900 0.000
Q25.5 Atresia of pulmonary artery
0.099 0.900 0.000
Q25.4 Other congenital malformations of aorta
0.099 0.900 0.000
Q25.3 Stenosis of aorta
0.099 0.900 0.000
Q25.2 Atresia of aorta
0.099 0.900 0.000
Q25.0 Patent ductus arteriosus
0.099 0.900 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.098 0.901 0.000
Q28.9 Congenital malformation of circulatory system, unspecified
0.097 0.903 0.000
Q28.8 Other specified congenital malformations of circulatory system
0.097 0.903 0.000
Q28.3 Other malformations of cerebral vessels
0.097 0.903 0.000
Q28.1 Other malformations of precerebral vessels
0.097 0.903 0.000
Q28.0 Arteriovenous malformation of precerebral vessels
0.097 0.903 0.000
C16.5 Lesser curvature of stomach, unspecified
0.096 0.904 0.000
C25.2 Tail of pancreas
0.096 0.904 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.096 0.904 0.000
C25.0 Head of pancreas
0.095 0.905 0.000
Q35-Q37 Cleft lip and cleft palate
0.095 0.905 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.095 0.905 0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified
0.094 0.906 0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions
0.094 0.906 0.000
Q20.6 Isomerism of atrial appendages
0.094 0.906 0.000
Q20.5 Discordant atrioventricular connexion
0.094 0.906 0.000
Q20.4 Double inlet ventricle
0.094 0.906 0.000
Q20.3 Discordant ventriculoarterial connexion
0.094 0.906 0.000
Q20.2 Double outlet left ventricle
0.094 0.906 0.000
Q20.1 Double outlet right ventricle
0.094 0.906 0.000
Q20.0 Common arterial trunk
0.094 0.906 0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified
0.094 0.906 0.000
Q22.8 Other congenital malformations of tricuspid valve
0.094 0.906 0.000
Q22.6 Hypoplastic right heart syndrome
0.094 0.906 0.000
Q22.5 Ebstein's anomaly
0.094 0.906 0.000
Q22.4 Congenital tricuspid stenosis
0.094 0.906 0.000
Q22.3 Other congenital malformations of pulmonary valve
0.094 0.906 0.000
Q22.2 Congenital pulmonary valve insufficiency
0.094 0.906 0.000
Q22.1 Congenital pulmonary valve stenosis
0.094 0.906 0.000
Q22.0 Pulmonary valve atresia
0.094 0.906 0.000
Q26.9 Congenital malformation of great vein, unspecified
0.094 0.906 0.000
Q26.8 Other congenital malformations of great veins
0.094 0.906 0.000
Q26.6 Portal vein-hepatic artery fistula
0.094 0.906 0.000
Q26.5 Anomalous portal venous connexion
0.094 0.906 0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified
0.094 0.906 0.000
Q26.3 Partial anomalous pulmonary venous connexion
0.094 0.906 0.000
Q26.2 Total anomalous pulmonary venous connexion
0.094 0.906 0.000
Q26.1 Persistent left superior vena cava
0.094 0.906 0.000
Q26.0 Congenital stenosis of vena cava
0.094 0.906 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.094 0.906 0.000
C24.9 Biliary tract, unspecified
0.094 0.906 0.000
Q80-Q89 Other congenital malformations
0.094 0.906 0.000
I34.1 Mitral (valve) prolapse
0.000 0.907 0.093
C15.5 Lower third of oesophagus
0.091 0.908 0.000
C24.0 Extrahepatic bile duct
0.091 0.909 0.000
C24.8 Overlapping lesion of biliary tract
0.091 0.909 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.090 0.909 0.000
Q55 Other congenital malformations of male genital organs
0.090 0.909 0.000
Q52 Other congenital malformations of female genitalia
0.090 0.909 0.000
C22.1 Intrahepatic bile duct carcinoma
0.090 0.910 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.090 0.910 0.000
I95.2 Hypotension due to drugs
0.000 0.912 0.088
Q66.7 Pes cavus
0.088 0.912 0.000
Q53 Undescended testicle
0.087 0.913 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.087 0.913 0.000
I42 Cardiomyopathy
0.000 0.913 0.086
I95.0 Idiopathic hypotension
0.000 0.914 0.086
Q66.2 Metatarsus varus
0.086 0.914 0.000
C16.0 Cardia
0.086 0.914 0.000
Q74 Other congenital malformations of limb(s)
0.086 0.914 0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified
0.085 0.915 0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts
0.085 0.915 0.000
Q51.6 Embryonic cyst of cervix
0.085 0.915 0.000
Q51.5 Agenesis and aplasia of cervix
0.085 0.915 0.000
Q51.4 Unicornate uterus
0.085 0.915 0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina
0.085 0.915 0.000
Q51.0 Agenesis and aplasia of uterus
0.085 0.915 0.000
Q54 Hypospadias
0.085 0.915 0.000
C22.7 Other specified carcinomas of liver
0.085 0.915 0.000
C22.4 Other sarcomas of liver
0.085 0.915 0.000
C22.3 Angiosarcoma of liver
0.085 0.915 0.000
C22.2 Hepatoblastoma
0.085 0.915 0.000
I95.1 Orthostatic hypotension
0.000 0.916 0.084
Q66.8 Other congenital deformities of feet
0.083 0.917 0.000
Q78 Other osteochondrodysplasias
0.082 0.918 0.000
Q75 Other congenital malformations of skull and face bones
0.082 0.918 0.000
Q73 Reduction defects of unspecified limb
0.082 0.918 0.000
Q72 Reduction defects of lower limb
0.082 0.918 0.000
Q71 Reduction defects of upper limb
0.082 0.918 0.000
Q70 Syndactyly
0.082 0.918 0.000
Q69 Polydactyly
0.082 0.918 0.000
Q68 Other congenital musculoskeletal deformities
0.082 0.918 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.082 0.918 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.081 0.919 0.000
Q76 Congenital malformations of spine and bony thorax
0.079 0.921 0.000
Q51.8 Other congenital malformations of uterus and cervix
0.078 0.921 0.000
C24.1 Ampulla of Vater
0.078 0.922 0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament
0.078 0.922 0.000
Q50.5 Embryonic cyst of broad ligament
0.078 0.922 0.000
Q50.3 Other congenital malformations of ovary
0.078 0.922 0.000
Q50.2 Congenital torsion of ovary
0.078 0.922 0.000
Q50.1 Developmental ovarian cyst
0.078 0.922 0.000
Q50.0 Congenital absence of ovary
0.078 0.922 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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