TreeWAS – Variant ID: rs34536443

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	0.001	0.999
E03 Other hypothyroidism	0.001	0.999
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.001	0.999
E00-E07 Disorders of thyroid gland	0.002	0.998
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998
Chapter IV Endocrine, nutritional and metabolic diseases	0.004	0.996
E10-E14 Diabetes mellitus	0.007	0.993
E10 Insulin-dependent diabetes mellitus	0.009	0.991
E10.9 Without complications	0.011	0.989
L40.9 Psoriasis, unspecified	0.021	0.979
L40.5 Arthropathic psoriasis	0.022	0.978
L40 Psoriasis	0.022	0.978
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.028	0.972
E05 Thyrotoxicosis [hyperthyroidism]	0.029	0.971
E16 Other disorders of pancreatic internal secretion	0.045	0.955
M06 Other rheumatoid arthritis	0.053	0.947
E16.2 Hypoglycaemia, unspecified	0.057	0.943
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.077	0.923
E05.0 Thyrotoxicosis with diffuse goitre	0.092	0.908
M05-M14 Inflammatory polyarthropathies	0.108	0.892
E50-E64 Other nutritional deficiencies	0.108	0.891
E05.9 Thyrotoxicosis, unspecified	0.119	0.881
E14 Unspecified diabetes mellitus	0.138	0.862
M07 Psoriatic and enteropathic arthropathies	0.145	0.855
M07.3 Other psoriatic arthropathies	0.171	0.829
M10 Gout	0.184	0.816
E53 Deficiency of other B group vitamins	0.187	0.813
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.200	0.800
M07.39 Other psoriatic arthropathies (Site unspecified)	0.208	0.792
E10.1 With ketoacidosis	0.221	0.779
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.227	0.773
M06.0 Seronegative rheumatoid arthritis	0.238	0.762
M10.9 Gout, unspecified	0.239	0.761
E14.3 With ophthalmic complications	0.240	0.760
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.240	0.760
E53.8 Deficiency of other specified B group vitamins	0.243	0.757
E10.3 With ophthalmic complications	0.243	0.757
L40.0 Psoriasis vulgaris	0.258	0.742
M05 Seropositive rheumatoid arthritis	0.269	0.731
E10.4 With neurological complications	0.278	0.722
E10.5 With peripheral circulatory complications	0.279	0.721
M06.98 Rheumatoid arthritis, unspecified (Other)	0.283	0.716
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.283	0.716
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.283	0.716
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.283	0.716
E03.8 Other specified hypothyroidism	0.284	0.716
E03.5 Myxoedema coma	0.284	0.716
E03.4 Atrophy of thyroid (acquired)	0.284	0.716
E03.3 Postinfectious hypothyroidism	0.284	0.716
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.284	0.716
E03.1 Congenital hypothyroidism without goitre	0.284	0.716
E03.0 Congenital hypothyroidism with diffuse goitre	0.284	0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.284	0.716
E00 Congenital iodine-deficiency syndrome	0.284	0.716
E02 Subclinical iodine-deficiency hypothyroidism	0.284	0.716
E12 Malnutrition-related diabetes mellitus	0.288	0.712
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.289	0.711
E10.8 With unspecified complications	0.289	0.711
E10.7 With multiple complications	0.289	0.711
E10.6 With other specified complications	0.289	0.711
E10.2 With renal complications	0.289	0.711
E10.0 With coma	0.289	0.711
M07.30 Other psoriatic arthropathies (Multiple sites)	0.291	0.709
E40-E46 Malnutrition	0.293	0.706
E06 Thyroiditis	0.295	0.705
L40.8 Other psoriasis	0.299	0.701
L40.4 Guttate psoriasis	0.299	0.701
L40.3 Pustulosis palmaris et plantaris	0.299	0.701
L40.2 Acrodermatitis continua	0.299	0.701
L40.1 Generalised pustular psoriasis	0.299	0.701
M11 Other crystal arthropathies	0.301	0.699
E07 Other disorders of thyroid	0.302	0.697
E15 Nondiabetic hypoglycaemic coma	0.303	0.697
E05.8 Other thyrotoxicosis	0.304	0.696
E05.5 Thyroid crisis or storm	0.304	0.696
E05.4 Thyrotoxicosis factitia	0.304	0.696
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.304	0.696
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.304	0.696
E16.9 Disorder of pancreatic internal secretion, unspecified	0.315	0.685
E16.8 Other specified disorders of pancreatic internal secretion	0.315	0.685
E16.4 Abnormal secretion of gastrin	0.315	0.685
E16.3 Increased secretion of glucagon	0.315	0.685
E16.1 Other hypoglycaemia	0.315	0.685
E16.0 Drug-induced hypoglycaemia without coma	0.315	0.685
M06.8 Other specified rheumatoid arthritis	0.321	0.679
M06.4 Inflammatory polyarthropathy	0.321	0.679
M06.3 Rheumatoid nodule	0.321	0.679
M06.2 Rheumatoid bursitis	0.321	0.679
M06.1 Adult-onset Still's disease	0.321	0.679
M10.99 Gout, unspecified (Site unspecified)	0.325	0.675
E70-E90 Metabolic disorders	0.326	0.674
M10.97 Gout, unspecified (Ankle and foot)	0.332	0.668
E55 Vitamin D deficiency	0.345	0.655
E13 Other specified diabetes mellitus	0.353	0.647
M14 Arthropathies in other diseases classified elsewhere	0.360	0.639
M12 Other specific arthropathies	0.360	0.639
M09 Juvenile arthritis in diseases classified elsewhere	0.360	0.639
M08 Juvenile arthritis	0.360	0.639
E64 Sequelae of malnutrition and other nutritional deficiencies	0.361	0.639
E63 Other nutritional deficiencies	0.361	0.639
E56 Other vitamin deficiencies	0.361	0.639
E51 Thiamine deficiency	0.361	0.639
E50 Vitamin A deficiency	0.361	0.639
E60 Dietary zinc deficiency	0.361	0.639
E59 Dietary selenium deficiency	0.361	0.639
E58 Dietary calcium deficiency	0.361	0.639
E54 Ascorbic acid deficiency	0.361	0.639
E52 Niacin deficiency [pellagra]	0.361	0.639
E14.9 Without complications	0.365	0.635
E61 Deficiency of other nutrient elements	0.367	0.633
E87 Other disorders of fluid, electrolyte and acid-base balance	0.367	0.633
E14.8 With unspecified complications	0.382	0.618
E14.7 With multiple complications	0.382	0.618
E14.6 With other specified complications	0.382	0.618
E14.5 With peripheral circulatory complications	0.382	0.618
E14.4 With neurological complications	0.382	0.618
E14.2 Withrenal complications	0.382	0.618
E14.1 With ketoacidosis	0.382	0.618
E14.0 With coma	0.382	0.618
M05.9 Seropositive rheumatoid arthritis, unspecified	0.384	0.616
M07.6 Other enteropathic arthropathies	0.387	0.613
M07.5 Arthropathy in ulcerative colitis	0.387	0.613
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.387	0.613
M07.2 Psoriatic spondylitis	0.387	0.613
M07.1 Arthritis mutilans	0.387	0.613
M07.0 Distal interphalangeal psoriatic arthropathy	0.387	0.613
L40-L45 Papulosquamous disorders	0.396	0.604
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.401	0.599
M10.96 Gout, unspecified (Lower leg)	0.401	0.599
M07.38 Other psoriatic arthropathies (Other)	0.406	0.594
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.406	0.594
M07.36 Other psoriatic arthropathies (Lower leg)	0.406	0.594
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.406	0.594
M07.34 Other psoriatic arthropathies (Hand)	0.406	0.594
M07.33 Other psoriatic arthropathies (Forearm)	0.406	0.594
M07.32 Other psoriatic arthropathies (Upper arm)	0.406	0.594
M07.31 Other psoriatic arthropathies (Shoulder region)	0.406	0.594
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.413	0.587
M10.4 Other secondary gout	0.415	0.585
M10.3 Gout due to impairment of renal function	0.415	0.585
M10.2 Drug-induced gout	0.415	0.585
M10.1 Lead-induced gout	0.415	0.585
M10.0 Idiopathic gout	0.415	0.585
E53.9 Vitamin B deficiency, unspecified	0.417	0.583
E53.1 Pyridoxine deficiency	0.417	0.583
E53.0 Riboflavin deficiency	0.417	0.583
M11.2 Other chondrocalcinosis	0.439	0.561
E87.0 Hyperosmolality and hypernatraemia	0.440	0.560
E87.6 Hypokalaemia	0.445	0.555
M06.08 Seronegative rheumatoid arthritis (Other)	0.453	0.546
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.453	0.546
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.453	0.546
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.453	0.546
M06.04 Seronegative rheumatoid arthritis (Hand)	0.453	0.546
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.453	0.546
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.453	0.546
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.453	0.546
M10.98 Gout, unspecified (Other)	0.454	0.546
M10.95 Gout, unspecified (Pelvic region and thigh)	0.454	0.546
M10.93 Gout, unspecified (Forearm)	0.454	0.546
M10.92 Gout, unspecified (Upper arm)	0.454	0.546
M10.91 Gout, unspecified (Shoulder region)	0.454	0.546
M10.90 Gout, unspecified (Multiple sites)	0.454	0.546
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.466	0.534
E80 Disorders of porphyrin and bilirubin metabolism	0.468	0.532
E88 Other metabolic disorders	0.469	0.531
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.470	0.530
L43 Lichen planus	0.474	0.526
M05.8 Other seropositive rheumatoid arthritis	0.475	0.524
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.475	0.524
M05.2 Rheumatoid vasculitis	0.475	0.524
M05.1 Rheumatoid lung disease	0.475	0.524
M05.0 Felty's syndrome	0.475	0.524
E11 Non-insulin-dependent diabetes mellitus	0.481	0.519
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.487	0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.487	0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.487	0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.487	0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.487	0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.487	0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.487	0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.487	0.513
E12.9 Without complications	0.489	0.511
E12.8 With unspecified complications	0.489	0.511
E12.7 With multiple complications	0.489	0.511
E12.6 With other specified complications	0.489	0.511
E12.5 With peripheral circulatory complications	0.489	0.511
E12.4 With neurological complications	0.489	0.511
E12.3 With ophthalmic complications	0.489	0.511
E12.2 With renal complications	0.489	0.511
E12.1 With ketoacidosis	0.489	0.511
E12.0 With coma	0.489	0.511
E20-E35 Disorders of other endocrine glands	0.490	0.510
E87.5 Hyperkalaemia	0.492	0.508
E44 Protein-energy malnutrition of moderate and mild degree	0.493	0.506
E45 Retarded development following protein-energy malnutrition	0.493	0.506
E43 Unspecified severe protein-energy malnutrition	0.493	0.506
E42 Marasmic kwashiorkor	0.493	0.506
E41 Nutritional marasmus	0.493	0.506
E40 Kwashiorkor	0.493	0.506
E06.9 Thyroiditis, unspecified	0.494	0.506
E06.5 Other chronic thyroiditis	0.494	0.506
E06.4 Drug-induced thyroiditis	0.494	0.506
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.494	0.506
E06.1 Subacute thyroiditis	0.494	0.506
E06.0 Acute thyroiditis	0.494	0.506
M11.9 Crystal arthropathy, unspecified	0.499	0.501
M11.8 Other specified crystal arthropathies	0.499	0.501
M11.1 Familial chondrocalcinosis	0.499	0.501
M11.0 Hydroxyapatite deposition disease	0.499	0.501
E73 Lactose intolerance	0.499	0.501
E07.8 Other specified disorders of thyroid	0.500	0.500
E07.1 Dyshormogenetic goitre	0.500	0.500
E07.0 Hypersecretion of calcitonin	0.500	0.500
E46 Unspecified protein-energy malnutrition	0.501	0.499
E06.3 Autoimmune thyroiditis	0.505	0.495
E87.3 Alkalosis	0.512	0.487
M06.19 Adult-onset Still's disease (Site unspecified)	0.513	0.487
M06.18 Adult-onset Still's disease (Other)	0.513	0.487
M06.17 Adult-onset Still's disease (Ankle and foot)	0.513	0.487
M06.16 Adult-onset Still's disease (Lower leg)	0.513	0.487
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.513	0.487
M06.14 Adult-onset Still's disease (Hand)	0.513	0.487
M06.13 Adult-onset Still's disease (Forearm)	0.513	0.487
M06.12 Adult-onset Still's disease (Upper arm)	0.513	0.487
M06.11 Adult-onset Still's disease (Shoulder region)	0.513	0.487
M06.10 Adult-onset Still's disease (Multiple sites)	0.513	0.487
M06.29 Rheumatoid bursitis (Site unspecified)	0.513	0.487
M06.28 Rheumatoid bursitis (Other)	0.513	0.487
M06.27 Rheumatoid bursitis (Ankle and foot)	0.513	0.487
M06.26 Rheumatoid bursitis (Lower leg)	0.513	0.487
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.513	0.487
M06.24 Rheumatoid bursitis (Hand)	0.513	0.487
M06.23 Rheumatoid bursitis (Forearm)	0.513	0.487
M06.22 Rheumatoid bursitis (Upper arm)	0.513	0.487
M06.21 Rheumatoid bursitis (Shoulder region)	0.513	0.487
M06.20 Rheumatoid bursitis (Multiple sites)	0.513	0.487
M06.39 Rheumatoid nodule (Site unspecified)	0.513	0.487
M06.38 Rheumatoid nodule (Other)	0.513	0.487
M06.37 Rheumatoid nodule (Ankle and foot)	0.513	0.487
M06.36 Rheumatoid nodule (Lower leg)	0.513	0.487
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.513	0.487
M06.34 Rheumatoid nodule (Hand)	0.513	0.487
M06.33 Rheumatoid nodule (Forearm)	0.513	0.487
M06.32 Rheumatoid nodule (Upper arm)	0.513	0.487
M06.31 Rheumatoid nodule (Shoulder region)	0.513	0.487
M06.30 Rheumatoid nodule (Multiple sites)	0.513	0.487
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.513	0.487
M06.48 Inflammatory polyarthropathy (Other)	0.513	0.487
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.513	0.487
M06.46 Inflammatory polyarthropathy (Lower leg)	0.513	0.487
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.513	0.487
M06.44 Inflammatory polyarthropathy (Hand)	0.513	0.487
M06.43 Inflammatory polyarthropathy (Forearm)	0.513	0.487
M06.42 Inflammatory polyarthropathy (Upper arm)	0.513	0.487
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.513	0.487
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.513	0.487
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.513	0.487
M06.88 Other specified rheumatoid arthritis (Other)	0.513	0.487
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.513	0.487
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.513	0.487
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.513	0.487
M06.84 Other specified rheumatoid arthritis (Hand)	0.513	0.487
M06.83 Other specified rheumatoid arthritis (Forearm)	0.513	0.487
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.513	0.487
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.513	0.487
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.513	0.487
E55.9 Vitamin D deficiency, unspecified	0.514	0.486
E84 Cystic fibrosis	0.516	0.484
E79 Disorders of purine and pyrimidine metabolism	0.516	0.484
E77 Disorders of glycoprotein metabolism	0.516	0.484
E76 Disorders of glycosaminoglycan metabolism	0.516	0.484
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.516	0.484
E74 Other disorders of carbohydrate metabolism	0.516	0.484
E72 Other disorders of amino-acid metabolism	0.516	0.484
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.516	0.484
E70 Disorders of aromatic amino-acid metabolism	0.516	0.484
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.516	0.484
E07.9 Disorder of thyroid, unspecified	0.518	0.482
E11.3 With ophthalmic complications	0.527	0.473
L43.9 Lichen planus, unspecified	0.530	0.470
E55.0 Rickets, active	0.530	0.470
E13.8 With unspecified complications	0.536	0.464
E13.7 With multiple complications	0.536	0.464
E13.6 With other specified complications	0.536	0.464
E13.5 With peripheral circulatory complications	0.536	0.464
E13.4 With neurological complications	0.536	0.464
E13.3 With ophthalmic complications	0.536	0.464
E13.2 With renal complications	0.536	0.464
E13.1 With ketoacidosis	0.536	0.464
E13.0 With coma	0.536	0.464
E87.2 Acidosis	0.537	0.463
M11.26 Other chondrocalcinosis (Lower leg)	0.539	0.461
E65-E68 Obesity and other hyperalimentation	0.539	0.461
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.539	0.461
M10.94 Gout, unspecified (Hand)	0.539	0.460
M08.9 Juvenile arthritis, unspecified	0.541	0.458
M08.8 Other juvenile arthritis	0.541	0.458
M08.4 Pauciarticular juvenile arthritis	0.541	0.458
M08.3 Juvenile polyarthritis (seronegative)	0.541	0.458
M08.2 Juvenile arthritis with systemic onset	0.541	0.458
M08.1 Juvenile ankylosing spondylitis	0.541	0.458
M08.0 Juvenile rheumatoid arthritis	0.541	0.458
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.541	0.458
M09.2 Juvenile arthritis in ulcerative colitis	0.541	0.458
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.541	0.458
M09.0 Juvenile arthritis in psoriasis	0.541	0.458
M12.8 Other specific arthropathies, not elsewhere classified	0.541	0.458
M12.5 Traumatic arthropathy	0.541	0.458
M12.4 Intermittent hydrarthrosis	0.541	0.458
M12.3 Palindromic rheumatism	0.541	0.458
M12.2 Villonodular synovitis (pigmented)	0.541	0.458
M12.1 Kaschin-Beck disease	0.541	0.458
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.541	0.458
M14.8 Arthropathies in other specified diseases classified elsewhere	0.541	0.458
M14.6 Neuropathic arthropathy	0.541	0.458
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.541	0.458
M14.4 Arthropathy in amyloidosis	0.541	0.458
M14.3 Lipoid dermatoarthritis	0.541	0.458
M14.2 Diabetic arthropathy	0.541	0.458
M14.1 Crystal arthropathy in other metabolic disorders	0.541	0.458
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.541	0.458
E50.9 Vitamin A deficiency, unspecified	0.541	0.458
E50.8 Other manifestations of vitamin A deficiency	0.541	0.458
E50.7 Other ocular manifestations of vitamin A deficiency	0.541	0.458
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.541	0.458
E50.5 Vitamin A deficiency with night blindness	0.541	0.458
E50.4 Vitamin A deficiency with keratomalacia	0.541	0.458
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.541	0.458
E50.2 Vitamin A deficiency with corneal xerosis	0.541	0.458
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.541	0.458
E50.0 Vitamin A deficiency with conjunctival xerosis	0.541	0.458
E51.9 Thiamine deficiency, unspecified	0.541	0.458
E51.8 Other manifestations of thiamine deficiency	0.541	0.458
E51.2 Wernicke's encephalopathy	0.541	0.458
E51.1 Beriberi	0.541	0.458
E56.9 Vitamin deficiency, unspecified	0.541	0.458
E56.8 Deficiency of other vitamins	0.541	0.458
E56.1 Deficiency of vitamin K	0.541	0.458
E56.0 Deficiency of vitamin E	0.541	0.458
E63.9 Nutritional deficiency, unspecified	0.541	0.458
E63.8 Other specified nutritional deficiencies	0.541	0.458
E63.1 Imbalance of constituents of food intake	0.541	0.458
E63.0 Essential fatty acid [EFA] deficiency	0.541	0.458
E64.9 Sequelae of unspecified nutritional deficiency	0.541	0.458
E64.8 Sequelae of other nutritional deficiencies	0.541	0.458
E64.3 Sequelae of rickets	0.541	0.458
E64.2 Sequelae of vitamin C deficiency	0.541	0.458
E64.1 Sequelae of vitamin A deficiency	0.541	0.458
E64.0 Sequelae of protein-energy malnutrition	0.541	0.458
E61.9 Deficiency of nutrient element, unspecified	0.546	0.454
E61.8 Deficiency of other specified nutrient elements	0.546	0.454
E61.7 Deficiency of multiple nutrient elements	0.546	0.454
E61.6 Vanadium deficiency	0.546	0.454
E61.5 Molybdenum deficiency	0.546	0.454
E61.4 Chromium deficiency	0.546	0.454
E61.3 Manganese deficiency	0.546	0.454
E61.2 Magnesium deficiency	0.546	0.454
E61.0 Copper deficiency	0.546	0.454
E87.4 Mixed disorder of acid-base balance	0.546	0.454
E89.0 Postprocedural hypothyroidism	0.549	0.451
E61.1 Iron deficiency	0.552	0.448
E85 Amyloidosis	0.552	0.448
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.558	0.442
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.558	0.442
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.558	0.442
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.558	0.442
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.558	0.442
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.558	0.442
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.558	0.442
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.558	0.442
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.558	0.442
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.560	0.440
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.560	0.440
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.560	0.440
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.560	0.440
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.560	0.440
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.560	0.440
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.560	0.440
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.560	0.440
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.560	0.440
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.560	0.440
M07.19 Arthritis mutilans (Site unspecified)	0.560	0.440
M07.18 Arthritis mutilans (Other)	0.560	0.440
M07.17 Arthritis mutilans (Ankle and foot)	0.560	0.440
M07.16 Arthritis mutilans (Lower leg)	0.560	0.440
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.560	0.440
M07.14 Arthritis mutilans (Hand)	0.560	0.440
M07.13 Arthritis mutilans (Forearm)	0.560	0.440
M07.12 Arthritis mutilans (Upper arm)	0.560	0.440
M07.11 Arthritis mutilans (Shoulder region)	0.560	0.440
M07.10 Arthritis mutilans (Multiple sites)	0.560	0.440
M07.29 Psoriatic spondylitis (Site unspecified)	0.560	0.440
M07.28 Psoriatic spondylitis (Other)	0.560	0.440
M07.27 Psoriatic spondylitis (Ankle and foot)	0.560	0.440
M07.26 Psoriatic spondylitis (Lower leg)	0.560	0.440
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.560	0.440
M07.24 Psoriatic spondylitis (Hand)	0.560	0.440
M07.23 Psoriatic spondylitis (Forearm)	0.560	0.440
M07.22 Psoriatic spondylitis (Upper arm)	0.560	0.440
M07.21 Psoriatic spondylitis (Shoulder region)	0.560	0.440
M07.20 Psoriatic spondylitis (Multiple sites)	0.560	0.440
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.560	0.440
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.560	0.440
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.560	0.440
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.560	0.440
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.560	0.440
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.560	0.440
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.560	0.440
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.560	0.440
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.560	0.440
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.560	0.440
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.560	0.440
M07.58 Arthropathy in ulcerative colitis (Other)	0.560	0.440
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.560	0.440
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.560	0.440
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.560	0.440
M07.54 Arthropathy in ulcerative colitis (Hand)	0.560	0.440
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.560	0.440
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.560	0.440
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.560	0.440
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.560	0.440
M07.69 Other enteropathic arthropathies (Site unspecified)	0.560	0.440
M07.68 Other enteropathic arthropathies (Other)	0.560	0.440
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.560	0.440
M07.66 Other enteropathic arthropathies (Lower leg)	0.560	0.440
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.560	0.440
M07.64 Other enteropathic arthropathies (Hand)	0.560	0.440
M07.63 Other enteropathic arthropathies (Forearm)	0.560	0.440
M07.62 Other enteropathic arthropathies (Upper arm)	0.560	0.440
M07.61 Other enteropathic arthropathies (Shoulder region)	0.560	0.440
M07.60 Other enteropathic arthropathies (Multiple sites)	0.560	0.440
L44 Other papulosquamous disorders	0.567	0.433
L41 Parapsoriasis	0.567	0.433
L45 Papulosquamous disorders in diseases classified elsewhere	0.567	0.433
L42 Pityriasis rosea	0.567	0.433
E80.4 Gilbert's syndrome	0.570	0.430
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.571	0.429
E87.7 Fluid overload	0.573	0.427
M10.09 Idiopathic gout (Site unspecified)	0.580	0.419
M10.08 Idiopathic gout (Other)	0.580	0.419
M10.07 Idiopathic gout (Ankle and foot)	0.580	0.419
M10.06 Idiopathic gout (Lower leg)	0.580	0.419
M10.05 Idiopathic gout (Pelvic region and thigh)	0.580	0.419
M10.04 Idiopathic gout (Hand)	0.580	0.419
M10.03 Idiopathic gout (Forearm)	0.580	0.419
M10.02 Idiopathic gout (Upper arm)	0.580	0.419
M10.01 Idiopathic gout (Shoulder region)	0.580	0.419
M10.00 Idiopathic gout (Multiple sites)	0.580	0.419
M10.19 Lead-induced gout (Site unspecified)	0.580	0.419
M10.18 Lead-induced gout (Other)	0.580	0.419
M10.17 Lead-induced gout (Ankle and foot)	0.580	0.419
M10.16 Lead-induced gout (Lower leg)	0.580	0.419
M10.15 Lead-induced gout (Pelvic region and thigh)	0.580	0.419
M10.14 Lead-induced gout (Hand)	0.580	0.419
M10.13 Lead-induced gout (Forearm)	0.580	0.419
M10.12 Lead-induced gout (Upper arm)	0.580	0.419
M10.11 Lead-induced gout (Shoulder region)	0.580	0.419
M10.10 Lead-induced gout (Multiple sites)	0.580	0.419
M10.29 Drug-induced gout (Site unspecified)	0.580	0.419
M10.28 Drug-induced gout (Other)	0.580	0.419
M10.27 Drug-induced gout (Ankle and foot)	0.580	0.419
M10.26 Drug-induced gout (Lower leg)	0.580	0.419
M10.25 Drug-induced gout (Pelvic region and thigh)	0.580	0.419
M10.24 Drug-induced gout (Hand)	0.580	0.419
M10.23 Drug-induced gout (Forearm)	0.580	0.419
M10.22 Drug-induced gout (Upper arm)	0.580	0.419
M10.21 Drug-induced gout (Shoulder region)	0.580	0.419
M10.20 Drug-induced gout (Multiple sites)	0.580	0.419
M10.39 Gout due to impairment of renal function (Site unspecified)	0.580	0.419
M10.38 Gout due to impairment of renal function (Other)	0.580	0.419
M10.37 Gout due to impairment of renal function (Ankle and foot)	0.580	0.419
M10.36 Gout due to impairment of renal function (Lower leg)	0.580	0.419
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)	0.580	0.419
M10.34 Gout due to impairment of renal function (Hand)	0.580	0.419
M10.33 Gout due to impairment of renal function (Forearm)	0.580	0.419
M10.32 Gout due to impairment of renal function (Upper arm)	0.580	0.419
M10.31 Gout due to impairment of renal function (Shoulder region)	0.580	0.419
M10.30 Gout due to impairment of renal function (Multiple sites)	0.580	0.419
M10.49 Other secondary gout (Site unspecified)	0.580	0.419
M10.48 Other secondary gout (Other)	0.580	0.419
M10.47 Other secondary gout (Ankle and foot)	0.580	0.419
M10.46 Other secondary gout (Lower leg)	0.580	0.419
M10.45 Other secondary gout (Pelvic region and thigh)	0.580	0.419
M10.44 Other secondary gout (Hand)	0.580	0.419
M10.43 Other secondary gout (Forearm)	0.580	0.419
M10.42 Other secondary gout (Upper arm)	0.580	0.419
M10.41 Other secondary gout (Shoulder region)	0.580	0.419
M10.40 Other secondary gout (Multiple sites)	0.580	0.419
E27 Other disorders of adrenal gland	0.583	0.416
E29 Testicular dysfunction	0.589	0.410
M11.29 Other chondrocalcinosis (Site unspecified)	0.598	0.402
M11.28 Other chondrocalcinosis (Other)	0.598	0.402
M11.27 Other chondrocalcinosis (Ankle and foot)	0.598	0.402
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.598	0.402
M11.24 Other chondrocalcinosis (Hand)	0.598	0.402
M11.23 Other chondrocalcinosis (Forearm)	0.598	0.402
M11.22 Other chondrocalcinosis (Upper arm)	0.598	0.402
M11.21 Other chondrocalcinosis (Shoulder region)	0.598	0.402

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations