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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs34645399
log Bayes Factor = 46.5
Chromosome 6   position 32,589,169  (GRCh37) Explore rs34645399 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
J30-J39 Other diseases of upper respiratory tract
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
J33.9 Nasal polyp, unspecified
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
J45 Asthma
0.000 0.001 0.999
J40-J47 Chronic lower respiratory diseases
0.000 0.001 0.999
J32 Chronic sinusitis
0.000 0.002 0.998
J33.0 Polyp of nasal cavity
0.000 0.003 0.997
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.005 0.995
# Top node
0.000 0.005 0.995
G35 Multiple sclerosis
0.000 0.006 0.994
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.006 0.994
J32.9 Chronic sinusitis, unspecified
0.000 0.007 0.993
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.007 0.993
Chapter VI Diseases of the nervous system
0.000 0.007 0.993
J84 Other interstitial pulmonary diseases
0.000 0.009 0.991
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.012 0.988
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.015 0.985
M06 Other rheumatoid arthritis
0.000 0.018 0.982
E05.9 Thyrotoxicosis, unspecified
0.000 0.019 0.981
D50-D53 Nutritional anaemias
0.000 0.028 0.972
M05-M14 Inflammatory polyarthropathies
0.000 0.030 0.969
E10.3 With ophthalmic complications
0.000 0.031 0.969
J30 Vasomotor and allergic rhinitis
0.000 0.033 0.967
D51 Vitamin B12 deficiency anaemia
0.000 0.039 0.961
J47 Bronchiectasis
0.000 0.052 0.948
D60-D64 Aplastic and other anaemias
0.000 0.052 0.948
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.058 0.942
J33.8 Other polyp of sinus
0.000 0.059 0.941
J30.1 Allergic rhinitis due to pollen
0.000 0.061 0.939
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.069 0.931
M05 Seropositive rheumatoid arthritis
0.000 0.092 0.908
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.094 0.906
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.100 0.900
E11 Non-insulin-dependent diabetes mellitus
0.000 0.102 0.898
E10.4 With neurological complications
0.000 0.105 0.895
E10.1 With ketoacidosis
0.000 0.106 0.894
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.114 0.886
E16 Other disorders of pancreatic internal secretion
0.000 0.118 0.882
D64 Other anaemias
0.000 0.118 0.882
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.130 0.870
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.136 0.864
G37 Other demyelinating diseases of central nervous system
0.000 0.139 0.861
G70-G73 Diseases of myoneural junction and muscle
0.000 0.141 0.859
J60-J70 Lung diseases due to external agents
0.000 0.142 0.858
E16.2 Hypoglycaemia, unspecified
0.000 0.153 0.847
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.156 0.844
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.159 0.841
J36 Peritonsillar abscess
0.000 0.165 0.835
D64.9 Anaemia, unspecified
0.000 0.166 0.834
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.168 0.832
J32.0 Chronic maxillary sinusitis
0.000 0.176 0.824
D61 Other aplastic anaemias
0.000 0.178 0.822
G20-G26 Extrapyramidal and movement disorders
0.000 0.185 0.815
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.188 0.812
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.189 0.811
J32.8 Other chronic sinusitis
0.000 0.193 0.807
J32.4 Chronic pansinusitis
0.000 0.197 0.802
E13 Other specified diabetes mellitus
0.000 0.200 0.800
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.201 0.799
E07 Other disorders of thyroid
0.000 0.213 0.787
J30.3 Other allergic rhinitis
0.000 0.219 0.781
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.220 0.780
M10 Gout
0.000 0.221 0.779
E50-E64 Other nutritional deficiencies
0.000 0.223 0.777
M11 Other crystal arthropathies
0.000 0.224 0.776
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.224 0.776
Chapter I Certain infectious and parasitic diseases
0.000 0.228 0.772
G70 Myasthenia gravis and other myoneural disorders
0.000 0.228 0.772
E11.9 Without complications
0.000 0.231 0.769
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.234 0.766
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.235 0.765
J69 Pneumonitis due to solids and liquids
0.000 0.238 0.762
M13 Other arthritis
0.000 0.243 0.757
E40-E46 Malnutrition
0.000 0.246 0.754
E14 Unspecified diabetes mellitus
0.000 0.246 0.753
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.250 0.750
E06 Thyroiditis
0.000 0.250 0.749
M06.0 Seronegative rheumatoid arthritis
0.000 0.263 0.737
D52 Folate deficiency anaemia
0.000 0.264 0.736
D61.9 Aplastic anaemia, unspecified
0.000 0.268 0.732
E11.5 With peripheral circulatory complications
0.000 0.273 0.727
J37 Chronic laryngitis and laryngotracheitis
0.000 0.276 0.724
D50 Iron deficiency anaemia
0.000 0.280 0.720
J80 Adult respiratory distress syndrome
0.000 0.282 0.718
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.5 With peripheral circulatory complications
0.000 0.283 0.717
E10.2 With renal complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
J33.1 Polypoid sinus degeneration
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
J45.8 Mixed asthma
0.000 0.283 0.717
J45.1 Nonallergic asthma
0.000 0.283 0.717
J95-J99 Other diseases of the respiratory system
0.000 0.283 0.717
J41 Simple and mucopurulent chronic bronchitis
0.000 0.283 0.716
J32.3 Chronic sphenoidal sinusitis
0.000 0.285 0.715
J32.1 Chronic frontal sinusitis
0.000 0.285 0.715
E05.8 Other thyrotoxicosis
0.000 0.287 0.713
E05.5 Thyroid crisis or storm
0.000 0.287 0.713
E05.4 Thyrotoxicosis factitia
0.000 0.287 0.713
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.287 0.713
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.287 0.713
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.287 0.713
G36 Other acute disseminated demyelination
0.000 0.288 0.712
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.288 0.712
J84.8 Other specified interstitial pulmonary diseases
0.000 0.290 0.710
J84.0 Alveolar and parietoalveolar conditions
0.000 0.290 0.710
G20 Parkinson's disease
0.000 0.290 0.710
G70.0 Myasthenia gravis
0.000 0.291 0.709
E11.3 With ophthalmic complications
0.000 0.291 0.709
D63.0 Anaemia in neoplastic disease
0.000 0.294 0.706
M06.8 Other specified rheumatoid arthritis
0.000 0.296 0.704
M06.3 Rheumatoid nodule
0.000 0.296 0.704
M06.2 Rheumatoid bursitis
0.000 0.296 0.704
M06.1 Adult-onset Still's disease
0.000 0.296 0.704
E53 Deficiency of other B group vitamins
0.000 0.297 0.702
J45.0 Predominantly allergic asthma
0.000 0.298 0.702
D53 Other nutritional anaemias
0.000 0.303 0.697
M12 Other specific arthropathies
0.000 0.305 0.695
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.305 0.695
M08 Juvenile arthritis
0.000 0.305 0.695
Chapter XXII Codes for special purposes
0.000 0.305 0.695
J69.0 Pneumonitis due to food and vomit
0.000 0.306 0.694
J30.2 Other seasonal allergic rhinitis
0.000 0.307 0.693
J30.0 Vasomotor rhinitis
0.000 0.307 0.693
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.309 0.691
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.311 0.689
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.311 0.689
D51.2 Transcobalamin II deficiency
0.000 0.311 0.689
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.311 0.689
E11.2 With renal complications
0.000 0.317 0.683
M14 Arthropathies in other diseases classified elsewhere
0.000 0.317 0.683
K90 Intestinal malabsorption
0.000 0.317 0.683
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.320 0.679
G63 Polyneuropathy in diseases classified elsewhere
0.000 0.321 0.679
M06.4 Inflammatory polyarthropathy
0.000 0.324 0.676
B95-B98 Bacterial, viral and other infectious agents
0.000 0.324 0.676
E07.9 Disorder of thyroid, unspecified
0.000 0.329 0.671
E15 Nondiabetic hypoglycaemic coma
0.000 0.332 0.668
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.333 0.667
G30-G32 Other degenerative diseases of the nervous system
0.000 0.336 0.664
E11.1 With ketoacidosis
0.000 0.341 0.659
E13.9 Without complications
0.000 0.343 0.657
G12 Spinal muscular atrophy and related syndromes
0.000 0.345 0.655
E14.3 With ophthalmic complications
0.000 0.346 0.654
M05.8 Other seropositive rheumatoid arthritis
0.000 0.349 0.651
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.349 0.651
M05.2 Rheumatoid vasculitis
0.000 0.349 0.651
M05.1 Rheumatoid lung disease
0.000 0.349 0.651
M05.0 Felty's syndrome
0.000 0.349 0.651
E53.8 Deficiency of other specified B group vitamins
0.000 0.351 0.649
E11.7 With multiple complications
0.000 0.356 0.644
E11.0 With coma
0.000 0.356 0.644
M00-M03 Infectious arthropathies
0.000 0.356 0.643
M10.9 Gout, unspecified
0.000 0.358 0.642
D50.8 Other iron deficiency anaemias
0.000 0.358 0.642
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.359 0.641
J46 Status asthmaticus
0.000 0.361 0.638
M11.2 Other chondrocalcinosis
0.000 0.362 0.638
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.000 0.363 0.637
J35 Chronic diseases of tonsils and adenoids
0.000 0.363 0.637
A30-A49 Other bacterial diseases
0.000 0.364 0.636
G81 Hemiplegia
0.000 0.365 0.635
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.367 0.633
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.368 0.632
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.368 0.632
E16.4 Abnormal secretion of gastrin
0.000 0.368 0.632
E16.3 Increased secretion of glucagon
0.000 0.368 0.632
E16.1 Other hypoglycaemia
0.000 0.368 0.632
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.368 0.632
D64.8 Other specified anaemias
0.000 0.368 0.632
D64.4 Congenital dyserythropoietic anaemia
0.000 0.368 0.632
D64.3 Other sideroblastic anaemias
0.000 0.368 0.632
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.368 0.632
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.368 0.632
D64.0 Hereditary sideroblastic anaemia
0.000 0.368 0.632
J09-J18 Influenza and pneumonia
0.000 0.369 0.631
D55-D59 Haemolytic anaemias
0.000 0.369 0.631
A80-A89 Viral infections of the central nervous system
0.000 0.370 0.630
E03.8 Other specified hypothyroidism
0.000 0.372 0.628
E11.6 With other specified complications
0.000 0.373 0.627
J30.4 Allergic rhinitis, unspecified
0.000 0.373 0.627
E11.8 With unspecified complications
0.000 0.377 0.623
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.381 0.619
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.381 0.619
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.381 0.619
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.381 0.619
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.381 0.619
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.381 0.619
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.381 0.619
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.381 0.619
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.381 0.619
M86-M90 Other osteopathies
0.000 0.382 0.617
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.383 0.617
G37.5 Concentric sclerosis [Balo]
0.000 0.383 0.617
G37.4 Subacute necrotising myelitis
0.000 0.383 0.617
G37.2 Central pontine myelinolysis
0.000 0.383 0.617
G37.1 Central demyelination of corpus callosum
0.000 0.383 0.617
G37.0 Diffuse sclerosis
0.000 0.383 0.617
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.383 0.617
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.383 0.617
Chapter VII Diseases of the eye and adnexa
0.000 0.383 0.617
M13.9 Arthritis, unspecified
0.000 0.384 0.616
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.000 0.384 0.616
J70 Respiratory conditions due to other external agents
0.000 0.385 0.615
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.385 0.615
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.385 0.615
J66 Airway disease due to specific organic dust
0.000 0.385 0.615
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.385 0.615
J62 Pneumoconiosis due to dust containing silica
0.000 0.385 0.615
J65 Pneumoconiosis associated with tuberculosis
0.000 0.385 0.615
J64 Unspecified pneumoconiosis
0.000 0.385 0.615
J60 Coalworker's pneumoconiosis
0.000 0.385 0.615
M91-M94 Chondropathies
0.000 0.386 0.614
G72 Other myopathies
0.000 0.386 0.614
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.388 0.612
G63.2 Diabetic polyneuropathy
0.000 0.391 0.609
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.000 0.395 0.605
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.400 0.600
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.401 0.599
E06.3 Autoimmune thyroiditis
0.000 0.403 0.597
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.405 0.595
J40 Bronchitis, not specified as acute or chronic
0.000 0.407 0.593
H53-H54 Visual disturbances and blindness
0.000 0.408 0.592
A63.0 Anogenital (venereal) warts
0.000 0.408 0.591
G71 Primary disorders of muscles
0.000 0.409 0.591
D61.8 Other specified aplastic anaemias
0.000 0.411 0.589
D61.3 Idiopathic aplastic anaemia
0.000 0.411 0.589
D61.2 Aplastic anaemia due to other external agents
0.000 0.411 0.589
D61.1 Drug-induced aplastic anaemia
0.000 0.411 0.589
D61.0 Constitutional aplastic anaemia
0.000 0.411 0.589
E65-E68 Obesity and other hyperalimentation
0.000 0.413 0.586
B97 Viral agents as the cause of diseases classified to other chapters
0.000 0.414 0.586
H53 Visual disturbances
0.000 0.416 0.584
G23 Other degenerative diseases of basal ganglia
0.000 0.416 0.584
G21 Secondary Parkinsonism
0.000 0.416 0.584
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.000 0.416 0.584
G22 Parkinsonism in diseases classified elsewhere
0.000 0.416 0.584
G80 Infantile cerebral palsy
0.000 0.416 0.584
E11.4 With neurological complications
0.000 0.417 0.583
G60 Hereditary and idiopathic neuropathy
0.000 0.418 0.582
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.418 0.582
G11 Hereditary ataxia
0.000 0.421 0.579
J32.2 Chronic ethmoidal sinusitis
0.000 0.421 0.579
E46 Unspecified protein-energy malnutrition
0.000 0.422 0.578
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.425 0.575
E13.8 With unspecified complications
0.000 0.426 0.574
E13.7 With multiple complications
0.000 0.426 0.574
E13.6 With other specified complications
0.000 0.426 0.574
E13.5 With peripheral circulatory complications
0.000 0.426 0.574
E13.4 With neurological complications
0.000 0.426 0.574
E13.3 With ophthalmic complications
0.000 0.426 0.574
E13.2 With renal complications
0.000 0.426 0.574
E13.1 With ketoacidosis
0.000 0.426 0.574
E13.0 With coma
0.000 0.426 0.574
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.000 0.427 0.573
G14 Postpolio syndrome
0.000 0.427 0.573
G10 Huntington's disease
0.000 0.427 0.573
J95.8 Other postprocedural respiratory disorders
0.000 0.428 0.572
H30-H36 Disorders of choroid and retina
0.000 0.429 0.571
G25 Other extrapyramidal and movement disorders
0.000 0.429 0.571
D52.9 Folate deficiency anaemia, unspecified
0.000 0.433 0.567
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.433 0.567
H36 Retinal disorders in diseases classified elsewhere
0.000 0.434 0.565
G61 Inflammatory polyneuropathy
0.000 0.435 0.565
E07.1 Dyshormogenetic goitre
0.000 0.436 0.564
E07.0 Hypersecretion of calcitonin
0.000 0.436 0.564
H36.0 Diabetic retinopathy
0.000 0.437 0.563
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.441 0.559
M10.4 Other secondary gout
0.000 0.441 0.558
M10.3 Gout due to impairment of renal function
0.000 0.441 0.558
M10.2 Drug-induced gout
0.000 0.441 0.558
M10.1 Lead-induced gout
0.000 0.441 0.558
M10.0 Idiopathic gout
0.000 0.441 0.558
M07 Psoriatic and enteropathic arthropathies
0.000 0.442 0.558
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.443 0.557
E63 Other nutritional deficiencies
0.000 0.443 0.557
E56 Other vitamin deficiencies
0.000 0.443 0.557
E51 Thiamine deficiency
0.000 0.443 0.557
E50 Vitamin A deficiency
0.000 0.443 0.557
E60 Dietary zinc deficiency
0.000 0.443 0.557
E59 Dietary selenium deficiency
0.000 0.443 0.557
E58 Dietary calcium deficiency
0.000 0.443 0.557
E54 Ascorbic acid deficiency
0.000 0.443 0.557
E52 Niacin deficiency [pellagra]
0.000 0.443 0.557
M11.9 Crystal arthropathy, unspecified
0.000 0.443 0.556
M11.8 Other specified crystal arthropathies
0.000 0.443 0.556
M11.1 Familial chondrocalcinosis
0.000 0.443 0.556
M11.0 Hydroxyapatite deposition disease
0.000 0.443 0.556
G64 Other disorders of peripheral nervous system
0.000 0.444 0.556
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.446 0.554
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.446 0.554
A75-A79 Rickettsioses
0.000 0.446 0.554
A70-A74 Other diseases caused by chlamydiae
0.000 0.446 0.554
A20-A28 Certain zoonotic bacterial diseases
0.000 0.446 0.554
A15-A19 Tuberculosis
0.000 0.446 0.554
M10.97 Gout, unspecified (Ankle and foot)
0.000 0.446 0.554
G70.9 Myoneural disorder, unspecified
0.000 0.447 0.553
G70.8 Other specified myoneural disorders
0.000 0.447 0.553
G70.2 Congenital and developmental myasthenia
0.000 0.447 0.553
G70.1 Toxic myoneural disorders
0.000 0.447 0.553
G12.2 Motor neuron disease
0.000 0.447 0.553
M50-M54 Other dorsopathies
0.000 0.448 0.551
G24 Dystonia
0.000 0.452 0.548
J69.8 Pneumonitis due to other solids and liquids
0.000 0.453 0.546
J69.1 Pneumonitis due to oils and essences
0.000 0.453 0.546
G83 Other paralytic syndromes
0.000 0.454 0.546
M13.8 Other specified arthritis
0.000 0.457 0.543
M13.1 Monoarthritis, not elsewhere classified
0.000 0.457 0.543
Chapter XV Pregnancy, childbirth and the puerperium
0.000 0.458 0.542
G81.9 Hemiplegia, unspecified
0.000 0.458 0.542
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.459 0.541
E45 Retarded development following protein-energy malnutrition
0.000 0.459 0.541
E43 Unspecified severe protein-energy malnutrition
0.000 0.459 0.541
E42 Marasmic kwashiorkor
0.000 0.459 0.541
E41 Nutritional marasmus
0.000 0.459 0.541
E40 Kwashiorkor
0.000 0.459 0.541
E14.8 With unspecified complications
0.000 0.460 0.540
E14.7 With multiple complications
0.000 0.460 0.540
E14.6 With other specified complications
0.000 0.460 0.540
E14.5 With peripheral circulatory complications
0.000 0.460 0.540
E14.4 With neurological complications
0.000 0.460 0.540
E14.2 Withrenal complications
0.000 0.460 0.540
E14.1 With ketoacidosis
0.000 0.460 0.540
E14.0 With coma
0.000 0.460 0.540
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.460 0.540
M11.26 Other chondrocalcinosis (Lower leg)
0.000 0.462 0.538
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.000 0.462 0.538
E06.5 Other chronic thyroiditis
0.000 0.462 0.537
E06.4 Drug-induced thyroiditis
0.000 0.462 0.537
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.462 0.537
E06.1 Subacute thyroiditis
0.000 0.462 0.537
E06.0 Acute thyroiditis
0.000 0.462 0.537
A41 Other septicaemia
0.000 0.466 0.534
M60-M63 Disorders of muscles
0.001 0.467 0.532
H53.1 Subjective visual disturbances
0.000 0.469 0.531
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.472 0.528
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.472 0.528
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.472 0.528
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.472 0.528
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.472 0.528
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.472 0.528
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.472 0.528
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.472 0.528
D52.8 Other folate deficiency anaemias
0.000 0.472 0.528
D52.1 Drug-induced folate deficiency anaemia
0.000 0.472 0.528
D52.0 Dietary folate deficiency anaemia
0.000 0.472 0.528
A87 Viral meningitis
0.000 0.472 0.528
J37.0 Chronic laryngitis
0.000 0.473 0.526
M45-M49 Spondylopathies
0.000 0.474 0.526
M13.0 Polyarthritis, unspecified
0.000 0.475 0.525
J35.1 Hypertrophy of tonsils
0.000 0.475 0.525
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.000 0.476 0.524
J39 Other diseases of upper respiratory tract
0.000 0.478 0.522
A65-A69 Other spirochaetal diseases
0.000 0.480 0.520
J37.1 Chronic laryngotracheitis
0.000 0.481 0.519
B65-B83 Helminthiases
0.000 0.481 0.519
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.481 0.518
D72 Other disorders of white blood cells
0.000 0.482 0.518
B99-B99 Other infectious diseases
0.000 0.483 0.517
D50.1 Sideropenic dysphagia
0.000 0.483 0.516
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
J96 Respiratory failure, not elsewhere classified
0.000 0.486 0.514
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.1 Mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.0 Simple chronic bronchitis
0.000 0.486 0.514
H53.4 Visual field defects
0.000 0.486 0.514
K90-K93 Other diseases of the digestive system
0.000 0.486 0.514
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.000 0.487 0.513
P90-P96 Other disorders originating in the perinatal period
0.000 0.489 0.511
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.000 0.489 0.511
P75-P78 Digestive system disorders of fetus and newborn
0.000 0.489 0.511
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.000 0.489 0.511
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.000 0.489 0.511
P35-P39 Infections specific to the perinatal period
0.000 0.489 0.511
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.000 0.489 0.511
P10-P15 Birth trauma
0.000 0.489 0.511
P05-P08 Disorders related to length of gestation and fetal growth
0.000 0.489 0.511
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.000 0.489 0.511
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.489 0.511
G36.9 Acute disseminated demyelination, unspecified
0.000 0.489 0.511
G36.8 Other specified acute disseminated demyelination
0.000 0.489 0.511
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.489 0.511
G36.0 Neuromyelitis optica [Devic]
0.000 0.489 0.511
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.489 0.510
H43-H45 Disorders of vitreous body and globe
0.000 0.491 0.509
M20-M25 Other joint disorders
0.000 0.492 0.508
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.000 0.492 0.508
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.494 0.506
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.000 0.495 0.505
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.495 0.505
M06.18 Adult-onset Still's disease (Other)
0.000 0.495 0.505
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.495 0.505
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.495 0.505
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.495 0.505
M06.14 Adult-onset Still's disease (Hand)
0.000 0.495 0.505
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.495 0.505
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.495 0.505
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.495 0.505
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.495 0.505
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.495 0.505
M06.28 Rheumatoid bursitis (Other)
0.000 0.495 0.505
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.495 0.505
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.495 0.505
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.495 0.505
M06.24 Rheumatoid bursitis (Hand)
0.000 0.495 0.505
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.495 0.505
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.495 0.505
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.495 0.505
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.495 0.505
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.495 0.505
M06.38 Rheumatoid nodule (Other)
0.000 0.495 0.505
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.495 0.505
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.495 0.505
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.495 0.505
M06.34 Rheumatoid nodule (Hand)
0.000 0.495 0.505
M06.33 Rheumatoid nodule (Forearm)
0.000 0.495 0.505
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.495 0.505
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.495 0.505
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.495 0.505
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.495 0.505
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.495 0.505
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.495 0.505
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.495 0.505
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.495 0.505
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.495 0.505
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.495 0.505
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.495 0.505
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.495 0.505
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.495 0.505
E53.9 Vitamin B deficiency, unspecified
0.000 0.496 0.504
E53.1 Pyridoxine deficiency
0.000 0.496 0.504
E53.0 Riboflavin deficiency
0.000 0.496 0.504
H53.9 Visual disturbance, unspecified
0.000 0.498 0.502
M10.99 Gout, unspecified (Site unspecified)
0.000 0.499 0.501
H53.0 Amblyopia ex anopsia
0.000 0.499 0.501
D53.9 Nutritional anaemia, unspecified
0.000 0.500 0.500
D53.8 Other specified nutritional anaemias
0.000 0.500 0.500
D53.2 Scorbutic anaemia
0.000 0.500 0.500
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.500 0.500
D53.0 Protein deficiency anaemia
0.000 0.500 0.500
E06.9 Thyroiditis, unspecified
0.000 0.500 0.500
M08.9 Juvenile arthritis, unspecified
0.000 0.501 0.498
M08.8 Other juvenile arthritis
0.000 0.501 0.498
M08.4 Pauciarticular juvenile arthritis
0.000 0.501 0.498
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.501 0.498
M08.2 Juvenile arthritis with systemic onset
0.000 0.501 0.498
M08.1 Juvenile ankylosing spondylitis
0.000 0.501 0.498
M08.0 Juvenile rheumatoid arthritis
0.000 0.501 0.498
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.501 0.498
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.501 0.498
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.501 0.498
M09.0 Juvenile arthritis in psoriasis
0.000 0.501 0.498
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.501 0.498
M12.5 Traumatic arthropathy
0.000 0.501 0.498
M12.4 Intermittent hydrarthrosis
0.000 0.501 0.498

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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