TreeWAS – Variant ID: rs34773007

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M20-M25 Other joint disorders	0.889	0.111	0.000
M70-M79 Other soft tissue disorders	0.885	0.115	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.882	0.118	0.000
M25 Other joint disorders, not elsewhere classified	0.881	0.119	0.000
M75 Shoulder lesions	0.880	0.120	0.000
M25.7 Osteophyte	0.873	0.127	0.000
M75.4 Impingement syndrome of shoulder	0.858	0.142	0.000
M75.1 Rotator cuff syndrome	0.853	0.147	0.000
M35 Other systemic involvement of connective tissue	0.851	0.149	0.000
M25.77 Osteophyte (Ankle and foot)	0.837	0.163	0.000
M35.3 Polymyalgia rheumatica	0.826	0.174	0.000
M25.74 Osteophyte (Hand)	0.820	0.180	0.000
M15-M19 Arthrosis	0.813	0.187	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.795	0.205	0.000
M18 Arthrosis of first carpometacarpal joint	0.791	0.209	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.748	0.252	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.739	0.261	0.000
M79.8 Other specified soft tissue disorders	0.736	0.264	0.000
M31 Other necrotising vasculopathies	0.734	0.266	0.000
M23 Internal derangement of knee	0.726	0.274	0.000
M77 Other enthesopathies	0.721	0.279	0.000
M25.71 Osteophyte (Shoulder region)	0.706	0.294	0.000
M22 Disorders of patella	0.697	0.303	0.000
M75.9 Shoulder lesion, unspecified	0.689	0.311	0.000
M79.86 Other specified soft tissue disorders (Lower leg)	0.683	0.317	0.000
M75.2 Bicipital tendinitis	0.683	0.317	0.000
M19 Other arthrosis	0.682	0.318	0.000
M75.5 Bursitis of shoulder	0.682	0.318	0.000
M25.8 Other specified joint disorders	0.679	0.321	0.000
M34 Systemic sclerosis	0.664	0.336	0.000
M25.78 Osteophyte (Other)	0.661	0.339	0.000
M91-M94 Chondropathies	0.660	0.339	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.658	0.342	0.000
M00-M03 Infectious arthropathies	0.653	0.347	0.000
M80-M85 Disorders of bone density and structure	0.653	0.347	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.649	0.351	0.000
M25.4 Effusion of joint	0.647	0.352	0.000
M24 Other specific joint derangements	0.645	0.355	0.000
M21 Other acquired deformities of limbs	0.644	0.355	0.000
M23.8 Other internal derangements of knee	0.644	0.356	0.000
M86-M90 Other osteopathies	0.641	0.359	0.000
M40-M43 Deforming dorsopathies	0.640	0.360	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.637	0.363	0.000
M33 Dermatopolymyositis	0.637	0.363	0.000
M32 Systemic lupus erythematosus	0.637	0.363	0.000
M30 Polyarteritis nodosa and related conditions	0.637	0.363	0.000
M25.5 Pain in joint	0.637	0.363	0.000
M70.6 Trochanteric bursitis	0.635	0.365	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.635	0.365	0.000
M76 Enthesopathies of lower limb, excluding foot	0.635	0.365	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.635	0.365	0.000
M71 Other bursopathies	0.635	0.365	0.000
M60-M63 Disorders of muscles	0.633	0.367	0.000
M25.9 Joint disorder, unspecified	0.631	0.369	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.631	0.369	0.000
M25.3 Other instability of joint	0.631	0.369	0.000
M25.2 Flail joint	0.631	0.369	0.000
M25.1 Fistula of joint	0.631	0.369	0.000
M25.0 Haemarthrosis	0.631	0.369	0.000
M75.8 Other shoulder lesions	0.631	0.369	0.000
M25.79 Osteophyte (Site unspecified)	0.626	0.374	0.000
M25.73 Osteophyte (Forearm)	0.626	0.374	0.000
M25.72 Osteophyte (Upper arm)	0.626	0.374	0.000
M25.70 Osteophyte (Multiple sites)	0.626	0.374	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.610	0.390	0.000
M35.8 Other specified systemic involvement of connective tissue	0.610	0.390	0.000
M35.7 Hypermobility syndrome	0.610	0.390	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.610	0.390	0.000
M35.5 Multifocal fibrosclerosis	0.610	0.390	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.610	0.390	0.000
M35.2 Behcet's disease	0.610	0.390	0.000
M35.1 Other overlap syndromes	0.610	0.390	0.000
M79.1 Myalgia	0.609	0.391	0.000
M31.6 Other giant cell arteritis	0.607	0.393	0.000
M79.7 Fibromyalgia	0.601	0.399	0.000
M79.0 Rheumatism, unspecified	0.590	0.410	0.000
M25.76 Osteophyte (Lower leg)	0.589	0.411	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.589	0.411	0.000
M35.0 Sicca syndrome [Sjogren]	0.588	0.412	0.000
M15 Polyarthrosis	0.583	0.417	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.581	0.419	0.000
M22.8 Other disorders of patella	0.579	0.421	0.000
M72 Fibroblastic disorders	0.573	0.427	0.000
M19.9 Arthrosis, unspecified	0.572	0.428	0.000
M77.9 Enthesopathy, unspecified	0.571	0.429	0.000
M79.9 Soft tissue disorder, unspecified	0.570	0.430	0.000
M79.5 Residual foreign body in soft tissue	0.570	0.430	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.570	0.430	0.000
M79.3 Panniculitis, unspecified	0.570	0.430	0.000
M79.2 Neuralgia and neuritis, unspecified	0.570	0.430	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.568	0.432	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.567	0.433	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.567	0.433	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.567	0.433	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.567	0.433	0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.560	0.440	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.559	0.441	0.000
M65-M68 Disorders of synovium and tendon	0.555	0.445	0.000
M77.0 Medial epicondylitis	0.555	0.445	0.000
M31.3 Wegener's granulomatosis	0.552	0.448	0.000
M23.4 Loose body in knee	0.544	0.455	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.538	0.462	0.000
M25.86 Other specified joint disorders (Lower leg)	0.535	0.465	0.000
M25.51 Pain in joint (Shoulder region)	0.531	0.469	0.000
M77.4 Metatarsalgia	0.531	0.469	0.000
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure	0.530	0.470	0.000
M70.8 Other soft tissue disorders related to use, overuse and pressure	0.530	0.470	0.000
M70.7 Other bursitis of hip	0.530	0.470	0.000
M70.5 Other bursitis of knee	0.530	0.470	0.000
M70.4 Prepatellar bursitis	0.530	0.470	0.000
M70.3 Other bursitis of elbow	0.530	0.470	0.000
M70.2 Olecranon bursitis	0.530	0.470	0.000
M70.1 Bursitis of hand	0.530	0.470	0.000
M70.0 Chronic crepitant synovitis of hand and wrist	0.530	0.470	0.000
M75.3 Calcific tendinitis of shoulder	0.529	0.470	0.000
M79.89 Other specified soft tissue disorders (Site unspecified)	0.528	0.472	0.000
M79.88 Other specified soft tissue disorders (Other)	0.528	0.472	0.000
M79.83 Other specified soft tissue disorders (Forearm)	0.528	0.472	0.000
M79.82 Other specified soft tissue disorders (Upper arm)	0.528	0.472	0.000
M79.81 Other specified soft tissue disorders (Shoulder region)	0.528	0.472	0.000
M79.80 Other specified soft tissue disorders (Multiple sites)	0.528	0.472	0.000
M31.9 Necrotising vasculopathy, unspecified	0.526	0.474	0.000
M31.8 Other specified necrotising vasculopathies	0.526	0.474	0.000
M31.7 Microscopic polyangiitis	0.526	0.474	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.526	0.474	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.526	0.474	0.000
M31.2 Lethal midline granuloma	0.526	0.474	0.000
M31.1 Thrombotic microangiopathy	0.526	0.474	0.000
M31.0 Hypersensitivity angiitis	0.526	0.474	0.000
M84 Disorders of continuity of bone	0.523	0.477	0.000
M23.9 Internal derangement of knee, unspecified	0.520	0.479	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.520	0.479	0.000
M23.5 Chronic instability of knee	0.520	0.479	0.000
M23.1 Discoid meniscus (congenital)	0.520	0.479	0.000
M23.0 Cystic meniscus	0.520	0.479	0.000
M05-M14 Inflammatory polyarthropathies	0.520	0.480	0.000
M19.0 Primary arthrosis of other joints	0.518	0.481	0.000
M77.8 Other enthesopathies, not elsewhere classified	0.517	0.483	0.000
M77.5 Other enthesopathy of foot	0.517	0.483	0.000
M77.3 Calcaneal spur	0.517	0.483	0.000
M77.2 Periarthritis of wrist	0.517	0.483	0.000
M77.1 Lateral epicondylitis	0.511	0.488	0.000
M20 Acquired deformities of fingers and toes	0.505	0.495	0.000
M80 Osteoporosis with pathological fracture	0.504	0.496	0.000
M34.9 Systemic sclerosis, unspecified	0.503	0.497	0.000
M93 Other osteochondropathies	0.502	0.498	0.000
M22.1 Recurrent subluxation of patella	0.499	0.500	0.000
M22.9 Disorder of patella, unspecified	0.499	0.500	0.000
M22.3 Other derangements of patella	0.499	0.500	0.000
M22.2 Patellofemoral disorders	0.499	0.500	0.000
M22.0 Recurrent dislocation of patella	0.499	0.500	0.000
M25.53 Pain in joint (Forearm)	0.497	0.503	0.000
M21.0 Valgus deformity, not elsewhere classified	0.495	0.505	0.000
M19.1 Posttraumatic arthrosis of other joints	0.490	0.509	0.000
M19.8 Other specified arthrosis	0.489	0.511	0.000
M19.2 Other secondary arthrosis	0.489	0.511	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.489	0.511	0.000
M00 Pyogenic arthritis	0.489	0.511	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.489	0.511	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.487	0.513	0.000
M25.88 Other specified joint disorders (Other)	0.487	0.513	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.487	0.513	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.487	0.513	0.000
M25.84 Other specified joint disorders (Hand)	0.487	0.513	0.000
M25.83 Other specified joint disorders (Forearm)	0.487	0.513	0.000
M25.82 Other specified joint disorders (Upper arm)	0.487	0.513	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.487	0.513	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.487	0.513	0.000
M24.0 Loose body in joint	0.487	0.513	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.481	0.519	0.000
M43 Other deforming dorsopathies	0.477	0.522	0.000
M19.91 Arthrosis, unspecified (Shoulder region)	0.477	0.523	0.000
M19.98 Arthrosis, unspecified (Other)	0.477	0.523	0.000
M88 Paget's disease of bone [osteitis deformans]	0.476	0.523	0.000
M34.8 Other forms of systemic sclerosis	0.476	0.524	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.476	0.524	0.000
M34.1 CR(E)ST syndrome	0.476	0.524	0.000
M34.0 Progressive systemic sclerosis	0.476	0.524	0.000
M20.2 Hallux rigidus	0.476	0.524	0.000
M79.10 Myalgia (Multiple sites)	0.476	0.524	0.000
M94 Other disorders of cartilage	0.474	0.526	0.000
M92 Other juvenile osteochondrosis	0.474	0.526	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.474	0.526	0.000
M25.47 Effusion of joint (Ankle and foot)	0.473	0.527	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.472	0.527	0.000
M25.46 Effusion of joint (Lower leg)	0.472	0.528	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.470	0.530	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.468	0.532	0.000
M02 Reactive arthropathies	0.468	0.532	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.468	0.532	0.000
M85 Other disorders of bone density and structure	0.468	0.532	0.000
M83 Adult osteomalacia	0.468	0.532	0.000
M82 Osteoporosis in diseases classified elsewhere	0.468	0.532	0.000
M22.4 Chondromalacia patellae	0.466	0.534	0.000
M25.49 Effusion of joint (Site unspecified)	0.464	0.536	0.000
M25.48 Effusion of joint (Other)	0.464	0.536	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.464	0.536	0.000
M25.44 Effusion of joint (Hand)	0.464	0.536	0.000
M25.43 Effusion of joint (Forearm)	0.464	0.536	0.000
M25.42 Effusion of joint (Upper arm)	0.464	0.536	0.000
M25.41 Effusion of joint (Shoulder region)	0.464	0.536	0.000
M25.40 Effusion of joint (Multiple sites)	0.464	0.536	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.463	0.537	0.000
M24.9 Joint derangement, unspecified	0.462	0.537	0.000
M24.7 Protrusio acetabuli	0.462	0.537	0.000
M24.6 Ankylosis of joint	0.462	0.537	0.000
M24.5 Contracture of joint	0.462	0.537	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.462	0.537	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.462	0.537	0.000
M24.2 Disorder of ligament	0.462	0.537	0.000
M79.79 Fibromyalgia (Site unspecified)	0.462	0.538	0.000
M21.9 Acquired deformity of limb, unspecified	0.462	0.538	0.000
M21.8 Other specified acquired deformities of limbs	0.462	0.538	0.000
M21.7 Unequal limb length (acquired)	0.462	0.538	0.000
M21.6 Other acquired deformities of ankle and foot	0.462	0.538	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.462	0.538	0.000
M21.4 Flat foot [pes planus] (acquired)	0.462	0.538	0.000
M21.2 Flexion deformity	0.462	0.538	0.000
M21.1 Varus deformity, not elsewhere classified	0.462	0.538	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.461	0.538	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.461	0.538	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.461	0.538	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.461	0.538	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.461	0.538	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.461	0.538	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.461	0.538	0.000
M50-M54 Other dorsopathies	0.460	0.540	0.000
M90 Osteopathies in diseases classified elsewhere	0.459	0.541	0.000
M87 Osteonecrosis	0.459	0.541	0.000
M86 Osteomyelitis	0.459	0.541	0.000
M42 Spinal osteochondrosis	0.459	0.541	0.000
M40 Kyphosis and lordosis	0.459	0.541	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.457	0.543	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.457	0.543	0.000
M30.2 Juvenile polyarteritis	0.457	0.543	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.457	0.543	0.000
M30.0 Polyarteritis nodosa	0.457	0.543	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.457	0.543	0.000
M32.8 Other forms of systemic lupus erythematosus	0.457	0.543	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.457	0.543	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.457	0.543	0.000
M33.9 Dermatopolymyositis, unspecified	0.457	0.543	0.000
M33.2 Polymyositis	0.457	0.543	0.000
M33.1 Other dermatomyositis	0.457	0.543	0.000
M33.0 Juvenile dermatomyositis	0.457	0.543	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.457	0.543	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.457	0.543	0.000
M36.3 Arthropathy in other blood disorders	0.457	0.543	0.000
M36.2 Haemophilic arthropathy	0.457	0.543	0.000
M36.1 Arthropathy in neoplastic disease	0.457	0.543	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.457	0.543	0.000
M25.59 Pain in joint (Site unspecified)	0.457	0.543	0.000
M25.58 Pain in joint (Other)	0.457	0.543	0.000
M25.52 Pain in joint (Upper arm)	0.457	0.543	0.000
M45-M49 Spondylopathies	0.455	0.544	0.001
M70.69 Trochanteric bursitis-Site unspec	0.455	0.544	0.000
M70.68 Trochanteric bursitis-Other	0.455	0.544	0.000
M70.67 Trochanteric bursitis-Ankle/Foot	0.455	0.544	0.000
M70.66 Trochanteric bursitis-Lower Leg	0.455	0.544	0.000
M70.64 Trochanteric bursitis-Hand	0.455	0.544	0.000
M70.63 Trochanteric bursitis-Forearm	0.455	0.544	0.000
M70.62 Trochanteric bursitis-Upper arm	0.455	0.544	0.000
M70.61 Trochanteric bursitis-Shldr region	0.455	0.544	0.000
M70.60 Trochanteric bursitis-Mult sites	0.455	0.544	0.000
M99 Biomechanical lesions, not elsewhere classified	0.455	0.545	0.000
M71.9 Bursopathy, unspecified	0.455	0.545	0.000
M71.8 Other specified bursopathies	0.455	0.545	0.000
M71.5 Other bursitis, not elsewhere classified	0.455	0.545	0.000
M71.4 Calcium deposit in bursa	0.455	0.545	0.000
M71.3 Other bursal cyst	0.455	0.545	0.000
M71.2 Synovial cyst of popliteal space [Baker]	0.455	0.545	0.000
M71.1 Other infective bursitis	0.455	0.545	0.000
M71.0 Abscess of bursa	0.455	0.545	0.000
M73.8 Other soft tissue disorders in diseases classified elsewhere	0.455	0.545	0.000
M73.1 Syphilitic bursitis	0.455	0.545	0.000
M73.0 Gonococcal bursitis	0.455	0.545	0.000
M76.9 Enthesopathy of lower limb, unspecified	0.455	0.545	0.000
M76.8 Other enthesopathies of lower limb, excluding foot	0.455	0.545	0.000
M76.7 Peroneal tendinitis	0.455	0.545	0.000
M76.6 Achilles tendinitis	0.455	0.545	0.000
M76.5 Patellar tendinitis	0.455	0.545	0.000
M76.4 Tibial collateral bursitis [Pellegrini-Stieda]	0.455	0.545	0.000
M76.3 Iliotibial band syndrome	0.455	0.545	0.000
M76.2 Iliac crest spur	0.455	0.545	0.000
M76.1 Psoas tendinitis	0.455	0.545	0.000
M76.0 Gluteal tendinitis	0.455	0.545	0.000
M25.56 Pain in joint (Lower leg)	0.454	0.546	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.453	0.546	0.000
M62 Other disorders of muscle	0.453	0.546	0.000
M61 Calcification and ossification of muscle	0.453	0.546	0.000
M60 Myositis	0.453	0.546	0.000
M25.09 Haemarthrosis (Site unspecified)	0.453	0.547	0.000
M25.08 Haemarthrosis (Other)	0.453	0.547	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.453	0.547	0.000
M25.06 Haemarthrosis (Lower leg)	0.453	0.547	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.453	0.547	0.000
M25.04 Haemarthrosis (Hand)	0.453	0.547	0.000
M25.03 Haemarthrosis (Forearm)	0.453	0.547	0.000
M25.02 Haemarthrosis (Upper arm)	0.453	0.547	0.000
M25.01 Haemarthrosis (Shoulder region)	0.453	0.547	0.000
M25.00 Haemarthrosis (Multiple sites)	0.453	0.547	0.000
M25.19 Fistula of joint (Site unspecified)	0.453	0.547	0.000
M25.18 Fistula of joint (Other)	0.453	0.547	0.000
M25.17 Fistula of joint (Ankle and foot)	0.453	0.547	0.000
M25.16 Fistula of joint (Lower leg)	0.453	0.547	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.453	0.547	0.000
M25.14 Fistula of joint (Hand)	0.453	0.547	0.000
M25.13 Fistula of joint (Forearm)	0.453	0.547	0.000
M25.12 Fistula of joint (Upper arm)	0.453	0.547	0.000
M25.11 Fistula of joint (Shoulder region)	0.453	0.547	0.000
M25.10 Fistula of joint (Multiple sites)	0.453	0.547	0.000
M25.29 Flail joint (Site unspecified)	0.453	0.547	0.000
M25.28 Flail joint (Other)	0.453	0.547	0.000
M25.27 Flail joint (Ankle and foot)	0.453	0.547	0.000
M25.26 Flail joint (Lower leg)	0.453	0.547	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.453	0.547	0.000
M25.24 Flail joint (Hand)	0.453	0.547	0.000
M25.23 Flail joint (Forearm)	0.453	0.547	0.000
M25.22 Flail joint (Upper arm)	0.453	0.547	0.000
M25.21 Flail joint (Shoulder region)	0.453	0.547	0.000
M25.20 Flail joint (Multiple sites)	0.453	0.547	0.000
M25.39 Other instability of joint (Site unspecified)	0.453	0.547	0.000
M25.38 Other instability of joint (Other)	0.453	0.547	0.000
M25.37 Other instability of joint (Ankle and foot)	0.453	0.547	0.000
M25.36 Other instability of joint (Lower leg)	0.453	0.547	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.453	0.547	0.000
M25.34 Other instability of joint (Hand)	0.453	0.547	0.000
M25.33 Other instability of joint (Forearm)	0.453	0.547	0.000
M25.32 Other instability of joint (Upper arm)	0.453	0.547	0.000
M25.31 Other instability of joint (Shoulder region)	0.453	0.547	0.000
M25.30 Other instability of joint (Multiple sites)	0.453	0.547	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.453	0.547	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.453	0.547	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.453	0.547	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.453	0.547	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.453	0.547	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.453	0.547	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.453	0.547	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.453	0.547	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.453	0.547	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.453	0.547	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.453	0.547	0.000
M25.98 Joint disorder, unspecified (Other)	0.453	0.547	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.453	0.547	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.453	0.547	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.453	0.547	0.000
M25.94 Joint disorder, unspecified (Hand)	0.453	0.547	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.453	0.547	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.453	0.547	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.453	0.547	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.453	0.547	0.000
M75.81 Other shoulder lesions, right shoulder	0.453	0.547	0.000
M25.57 Pain in joint (Ankle and foot)	0.451	0.549	0.000
M89 Other disorders of bone	0.449	0.550	0.000
M41 Scoliosis	0.446	0.553	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.442	0.558	0.000
M19.97 Arthrosis, unspecified (Ankle and foot)	0.440	0.560	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.438	0.562	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.437	0.562	0.000
M79.19 Myalgia (Site unspecified)	0.437	0.563	0.000
M79.18 Myalgia (Other)	0.437	0.563	0.000
M79.17 Myalgia (Ankle and foot)	0.437	0.563	0.000
M79.16 Myalgia (Lower leg)	0.437	0.563	0.000
M79.15 Myalgia (Pelvic region and thigh)	0.437	0.563	0.000
M79.14 Myalgia (Hand)	0.437	0.563	0.000
M79.13 Myalgia (Forearm)	0.437	0.563	0.000
M79.12 Myalgia (Upper arm)	0.437	0.563	0.000
M79.11 Myalgia (Shoulder region)	0.437	0.563	0.000
M77.02 Medial epicondylitis (Upper arm)	0.436	0.564	0.000
M24.1 Other articular cartilage disorders	0.435	0.565	0.000
M25.54 Pain in joint (Hand)	0.432	0.568	0.000
M79.78 Fibromyalgia (Other)	0.431	0.569	0.000
M79.77 Fibromyalgia (Ankle and foot)	0.431	0.569	0.000
M79.76 Fibromyalgia (Lower leg)	0.431	0.569	0.000
M79.75 Fibromyalgia (Pelvic region and thigh)	0.431	0.569	0.000
M79.74 Fibromyalgia (Hand)	0.431	0.569	0.000
M79.73 Fibromyalgia (Forearm)	0.431	0.569	0.000
M79.72 Fibromyalgia (Upper arm)	0.431	0.569	0.000
M79.71 Fibromyalgia (Shoulder region)	0.431	0.569	0.000
M79.70 Fibromyalgia (Multiple sites)	0.431	0.569	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.431	0.569	0.000
M21.3 Wrist or foot drop (acquired)	0.430	0.569	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.429	0.570	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.428	0.572	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.426	0.574	0.000
M79.08 Rheumatism, unspecified (Other)	0.423	0.577	0.000
M79.07 Rheumatism, unspecified (Ankle and foot)	0.423	0.577	0.000
M79.06 Rheumatism, unspecified (Lower leg)	0.423	0.577	0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.423	0.577	0.000
M79.04 Rheumatism, unspecified (Hand)	0.423	0.577	0.000
M79.03 Rheumatism, unspecified (Forearm)	0.423	0.577	0.000
M79.02 Rheumatism, unspecified (Upper arm)	0.423	0.577	0.000
M79.01 Rheumatism, unspecified (Shoulder region)	0.423	0.577	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.423	0.577	0.000
M79.6 Pain in limb	0.421	0.579	0.000
M15.9 Polyarthrosis, unspecified	0.418	0.582	0.000
M15.0 Primary generalised (osteo)arthrosis	0.418	0.582	0.000
M15.8 Other polyarthrosis	0.418	0.582	0.000
M15.4 Erosive (osteo)arthrosis	0.418	0.582	0.000
M15.3 Secondary multiple arthrosis	0.418	0.582	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.418	0.582	0.000
M15.1 Heberden's nodes (with arthropathy)	0.418	0.582	0.000
M19.96 Arthrosis, unspecified-Lower leg	0.417	0.583	0.000
M23.49 Loose body in knee-Unspec lig/men	0.414	0.586	0.000
M72.9 Fibroblastic disorder, unspecified	0.411	0.589	0.000
M72.8 Other fibroblastic disorders	0.411	0.589	0.000
M72.6 Necrotizing fasciitis	0.411	0.589	0.000
M72.5 Fasciitis, not elsewhere classified	0.411	0.589	0.000
M72.4 Pseudosarcomatous fibromatosis	0.411	0.589	0.000
M72.3 Nodular fasciitis	0.411	0.589	0.000
M72.2 Plantar fascial fibromatosis	0.411	0.589	0.000
M72.1 Knuckle pads	0.411	0.589	0.000
M19.92 Arthrosis, unspecified (Upper arm)	0.410	0.590	0.000
M77.99 Enthesopathy, unspecified (Site unspecified)	0.409	0.590	0.000
M77.98 Enthesopathy, unspecified (Other)	0.409	0.590	0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.409	0.590	0.000
M77.96 Enthesopathy, unspecified (Lower leg)	0.409	0.590	0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)	0.409	0.590	0.000
M77.94 Enthesopathy, unspecified (Hand)	0.409	0.590	0.000
M77.93 Enthesopathy, unspecified (Forearm)	0.409	0.590	0.000
M77.92 Enthesopathy, unspecified (Upper arm)	0.409	0.590	0.000
M77.90 Enthesopathy, unspecified (Multiple sites)	0.409	0.590	0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.409	0.591	0.000
M79.28 Neuralgia and neuritis, unspecified (Other)	0.409	0.591	0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.409	0.591	0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.409	0.591	0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.409	0.591	0.000
M79.24 Neuralgia and neuritis, unspecified (Hand)	0.409	0.591	0.000
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.409	0.591	0.000
M79.22 Neuralgia and neuritis, unspecified (Upper arm)	0.409	0.591	0.000
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)	0.409	0.591	0.000
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)	0.409	0.591	0.000
M79.39 Panniculitis, unspecified (Site unspecified)	0.409	0.591	0.000
M79.38 Panniculitis, unspecified (Other)	0.409	0.591	0.000
M79.37 Panniculitis, unspecified (Ankle and foot)	0.409	0.591	0.000
M79.36 Panniculitis, unspecified (Lower leg)	0.409	0.591	0.000
M79.35 Panniculitis, unspecified (Pelvic region and thigh)	0.409	0.591	0.000
M79.34 Panniculitis, unspecified (Hand)	0.409	0.591	0.000
M79.33 Panniculitis, unspecified (Forearm)	0.409	0.591	0.000
M79.32 Panniculitis, unspecified (Upper arm)	0.409	0.591	0.000
M79.31 Panniculitis, unspecified (Shoulder region)	0.409	0.591	0.000
M79.30 Panniculitis, unspecified (Multiple sites)	0.409	0.591	0.000
M79.49 Hypertrophy of (infrapatellar) fat pad-Site unspec	0.409	0.591	0.000
M79.48 Hypertrophy of (infrapatellar) fat pad (Other)	0.409	0.591	0.000
M79.47 Hypertrophy of (infrapatellar) fat pad (Ankle and foot)	0.409	0.591	0.000
M79.46 Hypertrophy of (infrapatellar) fat pad (Lower leg)	0.409	0.591	0.000
M79.45 Hypertrophy of (infrapatellar) fat pad (Pelvic region and thigh)	0.409	0.591	0.000
M79.44 Hypertrophy of (infrapatellar) fat pad (Hand)	0.409	0.591	0.000
M79.43 Hypertrophy of (infrapatellar) fat pad (Forearm)	0.409	0.591	0.000
M79.42 Hypertrophy of (infrapatellar) fat pad (Upper arm)	0.409	0.591	0.000
M79.41 Hypertrophy of (infrapatellar) fat pad (Shoulder region)	0.409	0.591	0.000
M79.40 Hypertrophy of (infrapatellar) fat pad (Multiple sites)	0.409	0.591	0.000
M79.59 Residual foreign body in soft tissue (Site unspecified)	0.409	0.591	0.000
M79.58 Residual foreign body in soft tissue (Other)	0.409	0.591	0.000
M79.57 Residual foreign body in soft tissue (Ankle and foot)	0.409	0.591	0.000
M79.56 Residual foreign body in soft tissue (Lower leg)	0.409	0.591	0.000
M79.55 Residual foreign body in soft tissue (Pelvic region and thigh)	0.409	0.591	0.000
M79.54 Residual foreign body in soft tissue (Hand)	0.409	0.591	0.000
M79.53 Residual foreign body in soft tissue (Forearm)	0.409	0.591	0.000
M79.52 Residual foreign body in soft tissue (Upper arm)	0.409	0.591	0.000
M79.51 Residual foreign body in soft tissue (Shoulder region)	0.409	0.591	0.000
M79.50 Residual foreign body in soft tissue (Multiple sites)	0.409	0.591	0.000
M79.99 Soft tissue disorder, unspecified (Site unspecified)	0.409	0.591	0.000
M79.98 Soft tissue disorder, unspecified (Other)	0.409	0.591	0.000
M79.97 Soft tissue disorder, unspecified (Ankle and foot)	0.409	0.591	0.000
M79.96 Soft tissue disorder, unspecified (Lower leg)	0.409	0.591	0.000
M79.95 Soft tissue disorder, unspecified (Pelvic region and thigh)	0.409	0.591	0.000
M79.94 Soft tissue disorder, unspecified (Hand)	0.409	0.591	0.000
M79.93 Soft tissue disorder, unspecified (Forearm)	0.409	0.591	0.000
M79.92 Soft tissue disorder, unspecified (Upper arm)	0.409	0.591	0.000
M79.91 Soft tissue disorder, unspecified (Shoulder region)	0.409	0.591	0.000
M79.90 Soft tissue disorder, unspecified (Multiple sites)	0.409	0.591	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.407	0.592	0.000
M16 Coxarthrosis [arthrosis of hip]	0.405	0.595	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.401	0.599	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.400	0.600	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.400	0.600	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.398	0.602	0.000
M66 Spontaneous rupture of synovium and tendon	0.398	0.602	0.000
M77.09 Medial epicondylitis (Site unspecified)	0.398	0.602	0.000
M77.08 Medial epicondylitis-Other	0.398	0.602	0.000
M77.07 Medial epicondylitis-Ankle/Foot	0.398	0.602	0.000
M77.06 Medial epicondylitis (Lower leg)	0.398	0.602	0.000
M77.05 Medial epicondylitis (Pelvic region and thigh)	0.398	0.602	0.000
M77.04 Medial epicondylitis-Hand	0.398	0.602	0.000
M77.03 Medial epicondylitis-Forearm	0.398	0.602	0.000
M77.01 Medial epicondylitis-Shldr region	0.398	0.602	0.000
M77.00 Medial epicondylitis (Multiple sites)	0.398	0.602	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.397	0.602	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.395	0.605	0.000
M25.50 Pain in joint (Multiple sites)	0.394	0.606	0.000
M23.47 Loose body in knee-Capsular lig	0.390	0.609	0.000
M23.46 Loose body in knee-O/unsp lat men	0.390	0.609	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.390	0.609	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.390	0.609	0.000
M23.43 Loose body in knee-Med lig/oth men	0.390	0.609	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.390	0.609	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.390	0.609	0.000
M23.40 Loose body in knee-Mult sites	0.390	0.609	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.390	0.610	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations