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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs35212593
log Bayes Factor = 18.8452
Chromosome 15   position 78,831,826  (GRCh37) Explore rs35212593 on Ensembl!
Variant rs35212593 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.000 1.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
J43.9 Emphysema, unspecified
0.000 0.000 1.000
I71 Aortic aneurysm and dissection
0.000 0.000 1.000
J43 Emphysema
0.000 0.000 1.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.000 1.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.001 0.999
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.004 0.996
I73 Other peripheral vascular diseases
0.000 0.005 0.995
Chapter X Diseases of the respiratory system
0.000 0.006 0.994
I70 Atherosclerosis
0.000 0.008 0.992
J90-J94 Other diseases of pleura
0.000 0.008 0.992
J92 Pleural plaque
0.000 0.013 0.987
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.013 0.987
I73.9 Peripheral vascular disease, unspecified
0.000 0.013 0.987
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.017 0.983
I60-I69 Cerebrovascular diseases
0.000 0.019 0.981
Chapter IX Diseases of the circulatory system
0.000 0.021 0.979
J42 Unspecified chronic bronchitis
0.000 0.022 0.978
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.027 0.973
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.030 0.970
J92.0 Pleural plaque with presence of asbestos
0.000 0.031 0.969
I60 Subarachnoid haemorrhage
0.000 0.036 0.964
J95-J99 Other diseases of the respiratory system
0.000 0.040 0.960
J60-J70 Lung diseases due to external agents
0.000 0.042 0.958
I67 Other cerebrovascular diseases
0.000 0.043 0.957
I69 Sequelae of cerebrovascular disease
0.000 0.057 0.943
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.060 0.940
J92.9 Pleural plaque without asbestos
0.000 0.061 0.939
J98 Other respiratory disorders
0.000 0.063 0.937
I27 Other pulmonary heart diseases
0.000 0.063 0.937
J90 Pleural effusion, not elsewhere classified
0.000 0.065 0.935
I26 Pulmonary embolism
0.000 0.066 0.934
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.068 0.932
J98.1 Pulmonary collapse
0.000 0.074 0.926
I27.9 Pulmonary heart disease, unspecified
0.000 0.079 0.921
I77 Other disorders of arteries and arterioles
0.000 0.083 0.917
I67.9 Cerebrovascular disease, unspecified
0.000 0.088 0.912
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.092 0.908
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.093 0.907
I73.0 Raynaud's syndrome
0.000 0.112 0.888
I69.3 Sequelae of cerebral infarction
0.000 0.112 0.888
I72 Other aneurysm
0.000 0.113 0.887
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.124 0.876
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.139 0.861
J86 Pyothorax
0.000 0.141 0.859
I67.8 Other specified cerebrovascular diseases
0.000 0.146 0.854
I60.8 Other subarachnoid haemorrhage
0.000 0.152 0.848
I67.1 Cerebral aneurysm, nonruptured
0.000 0.164 0.836
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.165 0.835
J43.2 Centrilobular emphysema
0.000 0.166 0.834
J93 Pneumothorax
0.000 0.168 0.832
J98.4 Other disorders of lung
0.000 0.170 0.830
J86.9 Pyothorax without fistula
0.000 0.173 0.827
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.173 0.827
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.175 0.825
I77.1 Stricture of artery
0.000 0.176 0.824
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.180 0.820
I72.0 Aneurysm of carotid artery
0.000 0.191 0.809
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.193 0.807
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.194 0.806
I77.0 Arteriovenous fistula, acquired
0.000 0.208 0.792
I71.0 Dissection of aorta [any part]
0.000 0.211 0.789
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.216 0.784
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.218 0.782
I70.0 Atherosclerosis of aorta
0.000 0.231 0.769
J93.1 Other spontaneous pneumothorax
0.000 0.231 0.769
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.233 0.767
J98.9 Respiratory disorder, unspecified
0.000 0.239 0.761
J60 Coalworker's pneumoconiosis
0.000 0.242 0.758
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.253 0.747
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.257 0.743
I72.8 Aneurysm of other specified arteries
0.000 0.258 0.742
I77.2 Rupture of artery
0.000 0.282 0.718
J41 Simple and mucopurulent chronic bronchitis
0.000 0.283 0.717
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.283 0.717
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.283 0.717
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.283 0.717
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.283 0.717
J43.1 Panlobular emphysema
0.000 0.283 0.717
J43.0 MacLeod's syndrome
0.000 0.283 0.717
J64 Unspecified pneumoconiosis
0.000 0.284 0.716
I78 Diseases of capillaries
0.000 0.285 0.715
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.287 0.713
I70.9 Generalised and unspecified atherosclerosis
0.000 0.289 0.711
I70.8 Atherosclerosis of other arteries
0.000 0.289 0.711
I28 Other diseases of pulmonary vessels
0.000 0.291 0.709
I61 Intracerebral haemorrhage
0.000 0.292 0.708
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.301 0.699
I00-I02 Acute rheumatic fever
0.000 0.301 0.699
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.301 0.699
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.305 0.695
I27.8 Other specified pulmonary heart diseases
0.000 0.308 0.692
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.309 0.691
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.309 0.691
J96 Respiratory failure, not elsewhere classified
0.000 0.312 0.688
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.313 0.687
J66 Airway disease due to specific organic dust
0.000 0.313 0.687
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.313 0.687
J62 Pneumoconiosis due to dust containing silica
0.000 0.313 0.687
J65 Pneumoconiosis associated with tuberculosis
0.000 0.313 0.687
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.313 0.686
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.313 0.686
I67.5 Moyamoya disease
0.000 0.313 0.686
I67.4 Hypertensive encephalopathy
0.000 0.313 0.686
I67.3 Progressive vascular leukoencephalopathy
0.000 0.313 0.686
J98.2 Interstitial emphysema
0.000 0.314 0.686
J69 Pneumonitis due to solids and liquids
0.000 0.318 0.682
I72.9 Aneurysm of unspecified site
0.000 0.319 0.681
J98.3 Compensatory emphysema
0.000 0.328 0.672
I27.1 Kyphoscoliotic heart disease
0.000 0.328 0.672
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.336 0.664
I77.5 Necrosis of artery
0.000 0.342 0.657
I77.4 Coeliac artery compression syndrome
0.000 0.342 0.657
I27.0 Primary pulmonary hypertension
0.000 0.347 0.653
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.352 0.648
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.352 0.648
I74 Arterial embolism and thrombosis
0.000 0.362 0.638
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.364 0.636
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.364 0.636
I72.1 Aneurysm of artery of upper extremity
0.000 0.364 0.636
J70 Respiratory conditions due to other external agents
0.000 0.367 0.633
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.371 0.629
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.372 0.628
I73.8 Other specified peripheral vascular diseases
0.000 0.374 0.626
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.380 0.620
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.380 0.619
J93.0 Spontaneous tension pneumothorax
0.000 0.381 0.619
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.383 0.617
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.384 0.616
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.385 0.615
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.387 0.612
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.390 0.610
I70.1 Atherosclerosis of renal artery
0.000 0.406 0.594
J98.6 Disorders of diaphragm
0.000 0.407 0.593
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.408 0.591
I79.1 Aortitis in diseases classified elsewhere
0.000 0.408 0.591
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.408 0.591
J85 Abscess of lung and mediastinum
0.000 0.408 0.591
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.410 0.590
J86.0 Pyothorax with fistula
0.000 0.414 0.586
J43.8 Other emphysema
0.000 0.422 0.578
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.422 0.578
I72.3 Aneurysm of iliac artery
0.000 0.424 0.576
J99.0 Rheumatoid lung disease
0.000 0.424 0.576
I68.0 Cerebral amyloid angiopathy
0.000 0.428 0.572
I72.4 Aneurysm of artery of lower extremity
0.000 0.438 0.562
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.448 0.552
J94 Other pleural conditions
0.000 0.450 0.550
J93.8 Other pneumothorax
0.000 0.454 0.545
I72.2 Aneurysm of renal artery
0.000 0.456 0.544
I77.3 Arterial fibromuscular dysplasia
0.000 0.458 0.542
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.467 0.533
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.467 0.533
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.467 0.533
J40 Bronchitis, not specified as acute or chronic
0.000 0.470 0.530
J69.8 Pneumonitis due to other solids and liquids
0.000 0.472 0.528
I77.8 Other specified disorders of arteries and arterioles
0.000 0.472 0.528
I67.2 Cerebral atherosclerosis
0.000 0.477 0.523
I28.8 Other specified diseases of pulmonary vessels
0.000 0.480 0.520
I77.6 Arteritis, unspecified
0.000 0.480 0.520
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.483 0.516
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.1 Mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.0 Simple chronic bronchitis
0.000 0.486 0.514
I62 Other nontraumatic intracranial haemorrhage
0.000 0.487 0.513
I78.9 Disease of capillaries, unspecified
0.000 0.487 0.513
I05-I09 Chronic rheumatic heart diseases
0.000 0.487 0.513
I27.2 Other secondary pulmonary hypertension
0.000 0.487 0.513
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.490 0.510
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.490 0.510
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.490 0.510
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.490 0.510
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.491 0.508
I28.1 Aneurysm of pulmonary artery
0.000 0.491 0.508
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.491 0.508
I02 Rheumatic chorea
0.000 0.499 0.501
I01 Rheumatic fever with heart involvement
0.000 0.499 0.501
I00 Rheumatic fever without mention of heart involvement
0.000 0.501 0.498
J96.9 Respiratory failure, unspecified
0.000 0.507 0.493
J96.1 Chronic respiratory failure
0.000 0.507 0.493
J96.0 Acute respiratory failure
0.000 0.507 0.493
I78.8 Other diseases of capillaries
0.000 0.507 0.493
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.507 0.493
J62.8 Pneumoconiosis due to other dust containing silica
0.000 0.508 0.492
J62.0 Pneumoconiosis due to talc dust
0.000 0.508 0.492
J63.8 Pneumoconiosis due to other specified inorganic dusts
0.000 0.508 0.492
J63.5 Stannosis
0.000 0.508 0.492
J63.4 Siderosis
0.000 0.508 0.492
J63.3 Graphite fibrosis (of lung)
0.000 0.508 0.492
J63.2 Berylliosis
0.000 0.508 0.492
J63.1 Bauxite fibrosis (of lung)
0.000 0.508 0.492
J63.0 Aluminosis (of lung)
0.000 0.508 0.492
J66.8 Airway disease due to other specific organic dusts
0.000 0.508 0.492
J66.2 Cannabinosis
0.000 0.508 0.492
J66.1 Flax-dresser's disease
0.000 0.508 0.492
J66.0 Byssinosis
0.000 0.508 0.492
J68.9 Unspecified respiratory condition due to chemicals, gases, fumes and vapours
0.000 0.508 0.492
J68.8 Other respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.508 0.492
J68.4 Chronic respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.508 0.492
J68.3 Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.508 0.492
J68.2 Upper respiratory inflammation due to chemicals, gases, fumes and vapours, not elsewhere classified
0.000 0.508 0.492
J68.1 Acute pulmonary oedema due to chemicals, gases, fumes and vapours
0.000 0.508 0.492
J68.0 Bronchitis and pneumonitis due to chemicals, gases, fumes and vapours
0.000 0.508 0.492
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.509 0.491
J69.1 Pneumonitis due to oils and essences
0.000 0.511 0.489
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.520 0.480
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.524 0.476
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.524 0.476
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.524 0.476
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.524 0.476
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.525 0.475
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.530 0.470
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.534 0.466
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.536 0.464
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.539 0.460
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.540 0.460
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.543 0.457
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.543 0.457
J70.9 Respiratory conditions due to unspecified external agent
0.000 0.546 0.454
J70.8 Respiratory conditions due to other specified external agents
0.000 0.546 0.454
J70.4 Drug-induced interstitial lung disorder, unspecified
0.000 0.546 0.454
J70.3 Chronic drug-induced interstitial lung disorders
0.000 0.546 0.454
J70.2 Acute drug-induced interstitial lung disorders
0.000 0.546 0.454
J70.0 Acute pulmonary manifestations due to radiation
0.000 0.546 0.454
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.549 0.451
I74.8 Embolism and thrombosis of other arteries
0.000 0.549 0.451
J93.9 Pneumothorax, unspecified
0.000 0.552 0.448
J09-J18 Influenza and pneumonia
0.000 0.554 0.446
J99.8 Respiratory disorders in other diseases classified elsewhere
0.000 0.557 0.443
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.557 0.443
J67.8 Hypersensitivity pneumonitis due to other organic dusts
0.000 0.558 0.441
J67.7 Air-conditioner and humidifier lung
0.000 0.558 0.441
J67.6 Maple-bark-stripper's lung
0.000 0.558 0.441
J67.5 Mushroom-worker's lung
0.000 0.558 0.441
J67.4 Maltworker's lung
0.000 0.558 0.441
J67.3 Suberosis
0.000 0.558 0.441
J67.1 Bagassosis
0.000 0.558 0.441
J67.0 Farmer's lung
0.000 0.558 0.441
J98.8 Other specified respiratory disorders
0.000 0.564 0.436
J95.8 Other postprocedural respiratory disorders
0.000 0.565 0.435
J69.0 Pneumonitis due to food and vomit
0.000 0.566 0.434
J46 Status asthmaticus
0.000 0.569 0.431
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.570 0.430
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.572 0.428
J98.5 Diseases of mediastinum, not elsewhere classified
0.001 0.572 0.427
J85.1 Abscess of lung with pneumonia
0.000 0.574 0.426
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.574 0.426
J85.3 Abscess of mediastinum
0.000 0.576 0.424
J85.0 Gangrene and necrosis of lung
0.000 0.576 0.424
J91 Pleural effusion in conditions classified elsewhere
0.000 0.576 0.424
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.577 0.423
J95.5 Postprocedural subglottic stenosis
0.000 0.586 0.414
J95.4 Mendelson's syndrome
0.000 0.586 0.414
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.586 0.414
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.586 0.414
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.586 0.414
I09 Other rheumatic heart diseases
0.000 0.588 0.412
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust
0.000 0.590 0.410
I74.5 Embolism and thrombosis of iliac artery
0.000 0.591 0.409
J67.2 Bird fancier's lung
0.000 0.592 0.408
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.595 0.405
J70.1 Chronic and other pulmonary manifestations due to radiation
0.000 0.599 0.400
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.600 0.400
J94.8 Other specified pleural conditions
0.000 0.604 0.396
I07 Rheumatic tricuspid valve diseases
0.000 0.605 0.395
J94.9 Pleural condition, unspecified
0.000 0.605 0.394
J94.1 Fibrothorax
0.000 0.605 0.394
J94.0 Chylous effusion
0.000 0.605 0.394
I61.8 Other intracerebral haemorrhage
0.000 0.610 0.390
J20-J22 Other acute lower respiratory infections
0.000 0.629 0.371
I05 Rheumatic mitral valve diseases
0.000 0.638 0.362
J85.2 Abscess of lung without pneumonia
0.000 0.638 0.362
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.640 0.359
I01.8 Other acute rheumatic heart disease
0.000 0.640 0.359
I01.2 Acute rheumatic myocarditis
0.000 0.640 0.359
I01.1 Acute rheumatic endocarditis
0.000 0.640 0.359
I01.0 Acute rheumatic pericarditis
0.000 0.640 0.359
I02.9 Rheumatic chorea without heart involvement
0.000 0.640 0.359
I02.0 Rheumatic chorea with heart involvement
0.000 0.640 0.359
J18 Pneumonia, organism unspecified
0.000 0.640 0.360
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.645 0.355
J96.09 Acute respiratory failure; Type unspecified
0.000 0.646 0.354
J96.01 Acute respiratory failure; Type II [hypercapnic]
0.000 0.646 0.354
J96.00 Acute respiratory failure; Type I [hypoxic]
0.000 0.646 0.354
J96.19 Chronic respiratory failure; Type unspecified
0.000 0.646 0.354
J96.11 Chronic respiratory failure; Type II [hypercapnic]
0.000 0.646 0.354
J96.10 Chronic respiratory failure; Type I [hypoxic]
0.000 0.646 0.354
J96.99 Respiratory failure, unspecified; Type unspecified
0.000 0.646 0.354
J96.91 Respiratory failure unspecified; Type II [hypercapnic]
0.000 0.646 0.354
J96.90 Respiratory failure, unspecified; Type I [hypoxic]
0.000 0.646 0.354
I78.1 Naevus, nonneoplastic
0.000 0.651 0.349
J95.0 Tracheostomy malfunction
0.000 0.651 0.348
J18.1 Lobar pneumonia, unspecified
0.000 0.655 0.345
I09.9 Rheumatic heart disease, unspecified
0.000 0.659 0.341
I06 Rheumatic aortic valve diseases
0.000 0.660 0.340
J10 Influenza due to identified influenza virus
0.000 0.665 0.335
I62.1 Nontraumatic extradural haemorrhage
0.000 0.669 0.331
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.674 0.326
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.000 0.680 0.320
J09 Influenza due to certain identified influenza virus
0.000 0.680 0.320
J13 Pneumonia due to Streptococcus pneumoniae
0.000 0.684 0.316
I07.1 Tricuspid insufficiency
0.000 0.689 0.311
I70.10 Atherosclerosis of renal artery (without gangrene)
0.001 0.691 0.308
I05.1 Rheumatic mitral insufficiency
0.000 0.694 0.306
J17 Pneumonia in diseases classified elsewhere
0.000 0.695 0.305
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.697 0.303
I09.8 Other specified rheumatic heart diseases
0.000 0.704 0.296
I09.2 Chronic rheumatic pericarditis
0.000 0.704 0.296
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.704 0.296
I09.0 Rheumatic myocarditis
0.000 0.704 0.296
J15 Bacterial pneumonia, not elsewhere classified
0.000 0.705 0.295
J80-J84 Other respiratory diseases principally affecting the interstitium
0.001 0.707 0.293
J12 Viral pneumonia, not elsewhere classified
0.000 0.713 0.287
I07.9 Tricuspid valve disease, unspecified
0.000 0.717 0.283
I07.8 Other tricuspid valve diseases
0.000 0.717 0.283
I07.2 Tricuspid stenosis with insufficiency
0.000 0.717 0.283
I07.0 Tricuspid stenosis
0.000 0.717 0.283
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.000 0.728 0.272
J45 Asthma
0.000 0.729 0.271
I05.0 Mitral stenosis
0.000 0.739 0.261
I05.8 Other mitral valve diseases
0.000 0.740 0.260
J14 Pneumonia due to Haemophilus influenzae
0.000 0.741 0.259
J18.2 Hypostatic pneumonia, unspecified
0.000 0.742 0.258
J21 Acute bronchiolitis
0.000 0.745 0.255
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.000 0.745 0.255
J84 Other interstitial pulmonary diseases
0.000 0.747 0.253
I99 Other and unspecified disorders of circulatory system
0.000 0.748 0.252
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.753 0.246
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.756 0.244
I06.8 Other rheumatic aortic valve diseases
0.000 0.756 0.244
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.756 0.244
I06.1 Rheumatic aortic insufficiency
0.000 0.756 0.244
J20 Acute bronchitis
0.000 0.757 0.243
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.757 0.243
J10.8 Influenza with other manifestations, influenza virus identified
0.000 0.760 0.240
J10.0 Influenza with pneumonia, influenza virus identified
0.000 0.760 0.240
I05.2 Mitral stenosis with insufficiency
0.000 0.763 0.237
J18.8 Other pneumonia, organism unspecified
0.000 0.765 0.234
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.766 0.234
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.766 0.234
I95 Hypotension
0.000 0.767 0.233
J16.8 Pneumonia due to other specified infectious organisms
0.000 0.770 0.230
J16.0 Chlamydial pneumonia
0.000 0.770 0.230
J94.2 Haemothorax
0.001 0.771 0.229
J15.2 Pneumonia due to staphylococcus
0.000 0.772 0.228
J15.8 Other bacterial pneumonia
0.000 0.775 0.225
J15.5 Pneumonia due to Escherichia coli
0.000 0.778 0.222
J18.9 Pneumonia, unspecified
0.000 0.780 0.220
J00-J06 Acute upper respiratory infections
0.000 0.780 0.220
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.780 0.220
J17.8 Pneumonia in other diseases classified elsewhere
0.000 0.781 0.219
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.782 0.217
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.782 0.217
I98.0 Cardiovascular syphilis
0.000 0.782 0.217
J15.4 Pneumonia due to other streptococci
0.000 0.783 0.217
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.783 0.216
I06.0 Rheumatic aortic stenosis
0.000 0.784 0.216
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.000 0.785 0.215
I63 Cerebral infarction
0.000 0.788 0.212
J15.3 Pneumonia due to streptococcus, group B
0.000 0.788 0.212
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.789 0.211
I95.1 Orthostatic hypotension
0.000 0.791 0.209
J15.9 Bacterial pneumonia, unspecified
0.000 0.791 0.209
I10-I15 Hypertensive diseases
0.000 0.793 0.207
J12.8 Other viral pneumonia
0.000 0.794 0.206
J12.3 Human metapneumovirus pneumonia
0.000 0.794 0.206
J12.2 Parainfluenza virus pneumonia
0.000 0.794 0.206
J12.1 Respiratory syncytial virus pneumonia
0.000 0.794 0.206
J12.0 Adenoviral pneumonia
0.000 0.794 0.206
F17.1 Harmful use
0.000 0.796 0.204
I05.9 Mitral valve disease, unspecified
0.000 0.799 0.201
J11 Influenza, virus not identified
0.000 0.800 0.199
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.000 0.803 0.197
J17.1 Pneumonia in viral diseases classified elsewhere
0.000 0.805 0.195
J45.8 Mixed asthma
0.000 0.806 0.194
J45.1 Nonallergic asthma
0.000 0.806 0.194
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.808 0.192
J15.0 Pneumonia due to Klebsiella pneumoniae
0.000 0.811 0.189
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.812 0.188
I95.8 Other hypotension
0.000 0.814 0.186
J17.3 Pneumonia in parasitic diseases
0.000 0.815 0.184
J21.8 Acute bronchiolitis due to other specified organisms
0.000 0.817 0.183
J21.1 Acute bronchiolitis due to human metapneumovirus
0.000 0.817 0.183
J21.0 Acute bronchiolitis due to respiratory syncytial virus
0.000 0.817 0.183
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.818 0.182
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.818 0.182
J84.0 Alveolar and parietoalveolar conditions
0.000 0.818 0.181
J84.8 Other specified interstitial pulmonary diseases
0.000 0.820 0.179
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.823 0.177
I97.0 Postcardiotomy syndrome
0.000 0.823 0.177
J20.7 Acute bronchitis due to echovirus
0.000 0.826 0.174
J20.6 Acute bronchitis due to rhinovirus
0.000 0.826 0.174
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.826 0.174
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.826 0.174
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.826 0.174
J20.2 Acute bronchitis due to streptococcus
0.000 0.826 0.174
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.826 0.174
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.826 0.174
J20.8 Acute bronchitis due to other specified organisms
0.000 0.827 0.173
J12.9 Viral pneumonia, unspecified
0.000 0.828 0.172
J21.9 Acute bronchiolitis, unspecified
0.000 0.828 0.172
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.830 0.170
J00 Acute nasopharyngitis [common cold]
0.000 0.836 0.164
J15.1 Pneumonia due to Pseudomonas
0.000 0.837 0.163
I65.1 Occlusion and stenosis of basilar artery
0.001 0.839 0.160
J17.2 Pneumonia in mycoses
0.000 0.840 0.159
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.842 0.158
F17 Mental and behavioural disorders due to use of tobacco
0.000 0.845 0.155
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.848 0.152
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.848 0.152
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.848 0.152
J20.9 Acute bronchitis, unspecified
0.000 0.848 0.152
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.850 0.149
I65.2 Occlusion and stenosis of carotid artery
0.000 0.851 0.149
I15 Secondary hypertension
0.000 0.851 0.149
I13 Hypertensive heart and renal disease
0.000 0.852 0.148
F17.2 Dependence syndrome
0.000 0.853 0.147
J11.8 Influenza with other manifestations, virus not identified
0.000 0.857 0.143
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.857 0.143
Z72.0 Tobacco use
0.000 0.858 0.142
I95.0 Idiopathic hypotension
0.000 0.861 0.139
I97.1 Other functional disturbances following cardiac surgery
0.000 0.862 0.138
J01 Acute sinusitis
0.000 0.862 0.138
Z72.1 Alcohol use
0.000 0.864 0.136
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.864 0.136
Z72 Problems related to lifestyle
0.000 0.864 0.135
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.870 0.130
J04 Acute laryngitis and tracheitis
0.000 0.872 0.128
J81 Pulmonary oedema
0.000 0.877 0.123
J03 Acute tonsillitis
0.000 0.877 0.123
J45.0 Predominantly allergic asthma
0.000 0.877 0.123
J02 Acute pharyngitis
0.000 0.878 0.122
I15.1 Hypertension secondary to other renal disorders
0.000 0.880 0.120
J47 Bronchiectasis
0.000 0.884 0.116
I87 Other disorders of veins
0.000 0.885 0.115
J05.1 Acute epiglottitis
0.000 0.886 0.114
J05.0 Acute obstructive laryngitis [croup]
0.000 0.886 0.114
J11.0 Influenza with pneumonia, virus not identified
0.001 0.886 0.113
I11 Hypertensive heart disease
0.000 0.887 0.113
F17.8 Other mental and behavioural disorders
0.000 0.889 0.111
F17.7 Residual and late-onset psychotic disorder
0.000 0.889 0.111
F17.6 Amnesic syndrome
0.000 0.889 0.111
F17.5 Psychotic disorder
0.000 0.889 0.111
F17.4 Withdrawal state with delirium
0.000 0.889 0.111
F17.3 Withdrawal state
0.000 0.889 0.111
I81 Portal vein thrombosis
0.000 0.889 0.111
I15.9 Seconday hypertension, unspecified
0.000 0.890 0.110
I88 Nonspecific lymphadenitis
0.000 0.890 0.110
I15.8 Other secondary hypertension
0.000 0.893 0.107
I15.2 Hypertension secondary to endocrine disorders
0.000 0.893 0.107
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.893 0.106
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.893 0.106
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.893 0.106
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.893 0.106
J18.0 Bronchopneumonia, unspecified
0.000 0.893 0.106
I85 Oesophageal varices
0.000 0.894 0.106
F17.9 Unspecified mental and behavioural disorder
0.000 0.894 0.106
I12 Hypertensive renal disease
0.000 0.894 0.106
Z72.2 Drug use
0.000 0.895 0.105
F17.0 Acute intoxication
0.000 0.896 0.104
I87.1 Compression of vein
0.000 0.897 0.102
J01.0 Acute maxillary sinusitis
0.000 0.900 0.100
J82 Pulmonary eosinophilia, not elsewhere classified
0.002 0.900 0.098
J01.8 Other acute sinusitis
0.000 0.901 0.099
J01.4 Acute pansinusitis
0.000 0.901 0.099
J01.3 Acute sphenoidal sinusitis
0.000 0.901 0.099
J01.1 Acute frontal sinusitis
0.000 0.901 0.099
I80 Phlebitis and thrombophlebitis
0.000 0.901 0.099
Z72.6 Gambling and betting
0.000 0.903 0.097
Z72.5 High-risk sexual behaviour
0.000 0.903 0.097
Z72.4 Inappropriate diet and eating habits
0.000 0.903 0.097
Z72.3 Lack of physical exercise
0.000 0.903 0.097
Z72.8 Other problems related to lifestyle
0.000 0.904 0.096
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.906 0.094
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.906 0.094
J01.2 Acute ethmoidal sinusitis
0.000 0.906 0.094
I85.0 Oesophageal varices with bleeding
0.000 0.906 0.094
I87.8 Other specified disorders of veins
0.000 0.907 0.093
J04.2 Acute laryngotracheitis
0.000 0.908 0.092
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.909 0.091
J02.0 Streptococcal pharyngitis
0.000 0.909 0.091
J04.1 Acute tracheitis
0.000 0.911 0.089
Z72.9 Problem related to lifestyle, unspecified
0.000 0.911 0.089
E11 Non-insulin-dependent diabetes mellitus
0.000 0.911 0.089
J03.8 Acute tonsillitis due to other specified organisms
0.000 0.912 0.088
J03.0 Streptococcal tonsillitis
0.000 0.912 0.088
J02.8 Acute pharyngitis due to other specified organisms
0.000 0.912 0.087
E11.3 With ophthalmic complications
0.000 0.913 0.087
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.913 0.087
I15.0 Renovascular hypertension
0.000 0.916 0.084
J01.9 Acute sinusitis, unspecified
0.000 0.916 0.084
J11.1 Influenza with other respiratory manifestations, virus not identified
0.001 0.916 0.083
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.916 0.083
I87.9 Disorder of vein, unspecified
0.000 0.917 0.083
I87.0 Postphlebitic syndrome
0.000 0.917 0.083
I63.8 Other cerebral infarction
0.000 0.918 0.082
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.919 0.081

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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