TreeWAS – Variant ID: rs35540212

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C19 Malignant neoplasm of rectosigmoid junction	0.042	0.958	0.000
C15-C26 Malignant neoplasms of digestive organs	0.030	0.970	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.030	0.970	0.000
C23 Malignant neoplasm of gallbladder	0.027	0.973	0.000
C22.0 Liver cell carcinoma	0.027	0.973	0.000
C22.1 Intrahepatic bile duct carcinoma	0.025	0.975	0.000
C20 Malignant neoplasm of rectum	0.025	0.975	0.000
C22.9 Liver, unspecified	0.024	0.976	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.024	0.976	0.000
C17 Malignant neoplasm of small intestine	0.023	0.976	0.000
C25 Malignant neoplasm of pancreas	0.023	0.977	0.000
C22.7 Other specified carcinomas of liver	0.021	0.978	0.000
C22.4 Other sarcomas of liver	0.021	0.978	0.000
C22.3 Angiosarcoma of liver	0.021	0.978	0.000
C22.2 Hepatoblastoma	0.021	0.978	0.000
C16 Malignant neoplasm of stomach	0.021	0.979	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.020	0.979	0.000
C21 Malignant neoplasm of anus and anal canal	0.020	0.980	0.000
C26.0 Intestinal tract, part unspecified	0.019	0.981	0.000
C25.2 Tail of pancreas	0.019	0.981	0.000
C17.9 Small intestine, unspecified	0.018	0.982	0.000
C17.0 Duodenum	0.018	0.982	0.000
C15 Malignant neoplasm of oesophagus	0.017	0.983	0.000
C25.1 Body of pancreas	0.017	0.983	0.000
C26.9 Ill-defined sites within the digestive system	0.017	0.983	0.000
C26.8 Overlapping lesion of digestive system	0.017	0.983	0.000
C26.1 Spleen	0.017	0.983	0.000
C17.8 Overlapping lesion of small intestine	0.017	0.983	0.000
C17.3 Meckel's diverticulum	0.017	0.983	0.000
C17.1 Jejunum	0.017	0.983	0.000
C25.8 Overlapping lesion of pancreas	0.017	0.983	0.000
C25.7 Other parts of pancreas	0.017	0.983	0.000
C25.4 Endocrine pancreas	0.017	0.983	0.000
C25.3 Pancreatic duct	0.017	0.983	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.017	0.983	0.000
C25.0 Head of pancreas	0.016	0.983	0.000
C16.5 Lesser curvature of stomach, unspecified	0.016	0.984	0.000
C17.2 Ileum	0.016	0.984	0.000
C16.8 Overlapping lesion of stomach	0.015	0.985	0.000
C16.6 Greater curvature of stomach, unspecified	0.015	0.985	0.000
C16.4 Pylorus	0.015	0.985	0.000
C16.3 Pyloric antrum	0.015	0.985	0.000
C16.2 Body of stomach	0.015	0.985	0.000
C16.1 Fundus of stomach	0.015	0.985	0.000
C24.9 Biliary tract, unspecified	0.015	0.985	0.000
C24.8 Overlapping lesion of biliary tract	0.015	0.985	0.000
C24.0 Extrahepatic bile duct	0.015	0.985	0.000
C16.0 Cardia	0.015	0.985	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.015	0.985	0.000
C21.2 Cloacogenic zone	0.015	0.985	0.000
C21.1 Anal canal	0.014	0.985	0.000
C25.9 Pancreas, unspecified	0.014	0.986	0.000
C16.9 Stomach, unspecified	0.014	0.986	0.000
C24.1 Ampulla of Vater	0.014	0.986	0.000
N87.1 Moderate cervical dysplasia	0.000	0.987	0.013
C21.0 Anus, unspecified	0.013	0.987	0.000
C15.8 Overlapping lesion of oesophagus	0.013	0.987	0.000
C15.3 Upper third of oesophagus	0.013	0.987	0.000
C15.2 Abdominal part of oesophagus	0.013	0.987	0.000
C15.1 Thoracic part of oesophagus	0.013	0.987	0.000
C15.0 Cervical part of oesophagus	0.013	0.987	0.000
C15.4 Middle third of oesophagus	0.012	0.988	0.000
C15.9 Oesophagus, unspecified	0.011	0.988	0.000
C15.5 Lower third of oesophagus	0.011	0.989	0.000
S82.8 Fractures of other parts of lower leg	0.009	0.990	0.000
S82.81 Fractures of other parts of lower leg (open)	0.008	0.992	0.000
S82.86 Maisonneuve's fracture	0.007	0.993	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.006	0.994	0.000
O72.0 Third-stage haemorrhage	0.006	0.994	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.994	0.006
S30.0 Contusion of lower back and pelvis	0.005	0.995	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.005	0.995	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.005	0.995	0.000
S52.00 Fracture of upper end of ulna (closed)	0.000	0.995	0.005
S31 Open wound of abdomen, lower back and pelvis	0.005	0.995	0.000
S32 Fracture of lumbar spine and pelvis	0.005	0.995	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.005	0.995	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.005	0.995	0.000
S31.4 Open wound of vagina and vulva	0.005	0.995	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.005	0.995	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.004	0.996	0.000
S30.1 Contusion of abdominal wall	0.004	0.996	0.000
N41 Inflammatory diseases of prostate	0.004	0.996	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.004	0.996	0.000
S32.4 Fracture of acetabulum	0.004	0.996	0.000
N87 Dysplasia of cervix uteri	0.000	0.996	0.004
I95.1 Orthostatic hypotension	0.000	0.996	0.004
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.004	0.996	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.004	0.996	0.000
S30.2 Contusion of external genital organs	0.004	0.996	0.000
N41.1 Chronic prostatitis	0.004	0.996	0.000
S32.1 Fracture of sacrum	0.004	0.996	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.004	0.996	0.000
S37 Injury of urinary and pelvic organs	0.004	0.996	0.000
S36 Injury of intra-abdominal organs	0.004	0.996	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.004	0.996	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.004	0.996	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.004	0.996	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.004	0.996	0.000
S31.5 Open wound of other and unspecified external genital organs	0.004	0.996	0.000
S31.3 Open wound of scrotum and testes	0.004	0.996	0.000
S31.2 Open wound of penis	0.004	0.996	0.000
S31.1 Open wound of abdominal wall	0.004	0.996	0.000
S31.0 Open wound of lower back and pelvis	0.004	0.996	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.004	0.996	0.000
S32.3 Fracture of ilium	0.004	0.996	0.000
S32.0 Fracture of lumbar vertebra	0.004	0.996	0.000
S32.2 Fracture of coccyx	0.004	0.996	0.000
S32.40 Fracture of acetabulum (closed)	0.004	0.996	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.004	0.996	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.004	0.996	0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.004	0.996	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.004	0.996	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.004	0.996	0.000
N87.0 Mild cervical dysplasia	0.000	0.996	0.003
N41.0 Acute prostatitis	0.003	0.997	0.000
F31 Bipolar affective disorder	0.000	0.997	0.003
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.003	0.997	0.000
S32.10 Fracture of sacrum (closed)	0.003	0.997	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.997	0.003
S32.41 Fracture of acetabulum (open)	0.003	0.997	0.000
N41.8 Other inflammatory diseases of prostate	0.003	0.997	0.000
N41.3 Prostatocystitis	0.003	0.997	0.000
N41.2 Abscess of prostate	0.003	0.997	0.000
O72 Postpartum haemorrhage	0.003	0.997	0.000
S32.11 Fracture of sacrum (open)	0.003	0.997	0.000
S33.7 Sprain and strain of other and unspecified parts of lumbar spine and pelvis	0.003	0.997	0.000
S33.6 Sprain and strain of sacro-iliac joint	0.003	0.997	0.000
S33.5 Sprain and strain of lumbar spine	0.003	0.997	0.000
S33.4 Traumatic rupture of symphysis pubis	0.003	0.997	0.000
S33.3 Dislocation of other and unspecified parts of lumbar spine and pelvis	0.003	0.997	0.000
S33.2 Dislocation of sacro-iliac and sacrococcygeal joint	0.003	0.997	0.000
S33.1 Dislocation of lumbar vertebra	0.003	0.997	0.000
S33.0 Traumatic rupture of lumbar intervertebral disk	0.003	0.997	0.000
S34.8 Injury of other and unspecified nerves at abdomen, lower back and pelvis level	0.003	0.997	0.000
S34.6 Injury of peripheral nerve(s) of abdomen, lower back and pelvis	0.003	0.997	0.000
S34.5 Injury of lumbar, sacral and pelvic sympathetic nerves	0.003	0.997	0.000
S34.4 Injury of lumbosacral plexus	0.003	0.997	0.000
S34.3 Injury of cauda equina	0.003	0.997	0.000
S34.2 Injury of nerve root of lumbar and sacral spine	0.003	0.997	0.000
S34.1 Other injury of lumbar spinal cord	0.003	0.997	0.000
S34.0 Concussion and oedema of lumbar spinal cord	0.003	0.997	0.000
S35.9 Injury of unspecified blood vessel at abdomen, lower back and pelvis level	0.003	0.997	0.000
S35.8 Injury of other blood vessels at abdomen, lower back and pelvis level	0.003	0.997	0.000
S35.7 Injury of multiple blood vessels at abdomen, lower back and pelvis level	0.003	0.997	0.000
S35.5 Injury of iliac blood vessels	0.003	0.997	0.000
S35.4 Injury of renal blood vessels	0.003	0.997	0.000
S35.3 Injury of portal or splenic vein	0.003	0.997	0.000
S35.2 Injury of coeliac or mesenteric artery	0.003	0.997	0.000
S35.1 Injury of inferior vena cava	0.003	0.997	0.000
S35.0 Injury of abdominal aorta	0.003	0.997	0.000
S36.9 Injury of unspecified intra-abdominal organ	0.003	0.997	0.000
S36.8 Injury of other intra-abdominal organs	0.003	0.997	0.000
S36.7 Injury of multiple intra-abdominal organs	0.003	0.997	0.000
S36.6 Injury of rectum	0.003	0.997	0.000
S36.5 Injury of colon	0.003	0.997	0.000
S36.4 Injury of small intestine	0.003	0.997	0.000
S36.3 Injury of stomach	0.003	0.997	0.000
S36.2 Injury of pancreas	0.003	0.997	0.000
S36.1 Injury of liver or gallbladder	0.003	0.997	0.000
S36.0 Injury of spleen	0.003	0.997	0.000
S37.9 Injury of unspecified pelvic organ	0.003	0.997	0.000
S37.8 Injury of other pelvic organs	0.003	0.997	0.000
S37.7 Injury of multiple pelvic organs	0.003	0.997	0.000
S37.6 Injury of uterus	0.003	0.997	0.000
S37.5 Injury of Fallopian tube	0.003	0.997	0.000
S37.4 Injury of ovary	0.003	0.997	0.000
S37.3 Injury of urethra	0.003	0.997	0.000
S37.2 Injury of bladder	0.003	0.997	0.000
S37.1 Injury of ureter	0.003	0.997	0.000
S37.0 Injury of kidney	0.003	0.997	0.000
S38.3 Traumatic amputation of other and unspecified parts of abdomen, lower back and pelvis	0.003	0.997	0.000
S38.2 Traumatic amputation of external genital organs	0.003	0.997	0.000
S38.1 Crushing injury of other and unspecified parts of abdomen, lower back and pelvis	0.003	0.997	0.000
S38.0 Crushing injury of external genital organs	0.003	0.997	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.997	0.003
S32.30 Fracture of ilium (closed)	0.003	0.997	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.003	0.997	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.997	0.003
S32.00 Fracture of lumbar vertebra (closed)	0.003	0.997	0.000
S32.5 Fracture of pubis	0.003	0.997	0.000
S32.01 Fracture of lumbar vertebra (open)	0.003	0.997	0.000
S32.31 Fracture of ilium (open)	0.003	0.997	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.003	0.997	0.000
N87.2 Severe cervical dysplasia, not elsewhere classified	0.000	0.997	0.003
O72.2 Delayed and secondary postpartum haemorrhage	0.003	0.997	0.000
S32.21 Fracture of coccyx (open)	0.003	0.997	0.000
S32.20 Fracture of coccyx (closed)	0.003	0.997	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.997	0.003
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.997	0.003
D03.6 Melanoma in situ of upper limb, including shoulder	0.003	0.997	0.000
F31.8 Other bipolar affective disorders	0.000	0.997	0.003
F31.7 Bipolar affective disorder, currently in remission	0.000	0.997	0.003
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.997	0.003
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.997	0.003
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.997	0.003
F33.9 Recurrent depressive disorder, unspecified	0.000	0.997	0.003
O72.3 Postpartum coagulation defects	0.002	0.997	0.000
O47.9 False labour, unspecified	0.003	0.997	0.000
S82 Fracture of lower leg, including ankle	0.003	0.997	0.000
S36.01 Injury of spleen (with open wound into cavity)	0.002	0.997	0.000
S36.00 Injury of spleen (without open wound into cavity)	0.002	0.997	0.000
S36.11 Injury of liver or gallbladder (with open wound into cavity)	0.002	0.997	0.000
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.002	0.997	0.000
S36.21 Injury of pancreas (with open wound into cavity)	0.002	0.997	0.000
S36.20 Injury of pancreas (without open wound into cavity)	0.002	0.997	0.000
S36.31 Injury of stomach (with open wound into cavity)	0.002	0.997	0.000
S36.30 Injury of stomach (without open wound into cavity)	0.002	0.997	0.000
S36.41 Injury of small intestine (with open wound into cavity)	0.002	0.997	0.000
S36.40 Injury of small intestine (without open wound into cavity)	0.002	0.997	0.000
S36.51 Injury of colon (with open wound into cavity)	0.002	0.997	0.000
S36.50 Injury of colon (without open wound into cavity)	0.002	0.997	0.000
S36.61 Injury of rectum (with open wound into cavity)	0.002	0.997	0.000
S36.60 Injury of rectum (without open wound into cavity)	0.002	0.997	0.000
S36.71 Injury of multiple intra-abdominal organs (with open wound into cavity)	0.002	0.997	0.000
S36.70 Injury of multiple intra-abdominal organs (without open wound into cavity)	0.002	0.997	0.000
S36.81 Injury of other intra-abdominal organs (with open wound into cavity)	0.002	0.997	0.000
S36.80 Injury of other intra-abdominal organs (without open wound into cavity)	0.002	0.997	0.000
S36.91 Injury of unspecified intra-abdominal organ (with open wound into cavity)	0.002	0.997	0.000
S36.90 Injury of unspecified intra-abdominal organ (without open wound into cavity)	0.002	0.997	0.000
S37.01 Injury of kidney (with open wound into cavity)	0.002	0.997	0.000
S37.00 Injury of kidney (without open wound into cavity)	0.002	0.997	0.000
S37.11 Injury of ureter (with open wound into cavity)	0.002	0.997	0.000
S37.10 Injury of ureter (without open wound into cavity)	0.002	0.997	0.000
S37.21 Injury of bladder (with open wound into cavity)	0.002	0.997	0.000
S37.20 Injury of bladder (without open wound into cavity)	0.002	0.997	0.000
S37.31 Injury of urethra (with open wound into cavity)	0.002	0.997	0.000
S37.30 Injury of urethra (without open wound into cavity)	0.002	0.997	0.000
S37.41 Injury of ovary (with open wound into cavity)	0.002	0.997	0.000
S37.40 Injury of ovary (without open wound into cavity)	0.002	0.997	0.000
S37.51 Injury of fallopian tube (with open wound into cavity)	0.002	0.997	0.000
S37.50 Injury of fallopian tube (without open wound into cavity)	0.002	0.997	0.000
S37.61 Injury of uterus (with open wound into cavity)	0.002	0.997	0.000
S37.60 Injury of uterus (without open wound into cavity)	0.002	0.997	0.000
S37.71 Injury of multiple pelvic organs (with open wound into cavity)	0.002	0.997	0.000
S37.70 Injury of multiple pelvic organs (without open wound into cavity)	0.002	0.997	0.000
S37.81 Injury of other pelvic organs (with open wound into cavity)	0.002	0.997	0.000
S37.80 Injury of other pelvic organs (without open wound into cavity)	0.002	0.997	0.000
S37.91 Injury of unspecified pelvic organ (with open wound into cavity)	0.002	0.997	0.000
S37.90 Injury of unspecified pelvic organ (without open wound into cavity)	0.002	0.997	0.000
F33 Recurrent depressive disorder	0.000	0.997	0.003
S32.51 Fracture of pubis (open)	0.002	0.997	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.998	0.002
N87.9 Dysplasia of cervix uteri, unspecified	0.000	0.998	0.002
F30-F39 Mood [affective] disorders	0.000	0.998	0.002
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.002	0.998	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.002	0.998	0.000
S52.0 Fracture of upper end of ulna	0.000	0.998	0.002
D03.7 Melanoma in situ of lower limb, including hip	0.002	0.998	0.000
I73.0 Raynaud's syndrome	0.000	0.998	0.002
S82.1 Fracture of upper end of tibia	0.002	0.998	0.000
C18 Malignant neoplasm of colon	0.002	0.998	0.000
D03.4 Melanoma in situ of scalp and neck	0.002	0.998	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.998	0.002
S82.3 Fracture of lower end of tibia	0.002	0.998	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.002	0.998	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.002	0.998	0.000
O72.1 Other immediate postpartum haemorrhage	0.002	0.998	0.000
D03 Melanoma in situ	0.002	0.998	0.000
S82.7 Multiple fractures of lower leg	0.002	0.998	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.998	0.002
S82.10 Fracture of upper end of tibia (closed)	0.002	0.998	0.000
F30 Manic episode	0.000	0.998	0.002
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.002	0.998	0.000
S82.30 Fracture of lower end of tibia (closed)	0.002	0.998	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.998	0.002
S82.9 Fracture of lower leg, part unspecified	0.002	0.998	0.000
R52.2 Other chronic pain	0.002	0.998	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.002	0.998	0.000
E23.0 Hypopituitarism	0.000	0.998	0.002
F33.8 Other recurrent depressive disorders	0.000	0.998	0.002
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.998	0.002
F32.1 Moderate depressive episode	0.000	0.998	0.002
C18.1 Appendix	0.002	0.998	0.000
F38 Other mood [affective] disorders	0.000	0.998	0.002
F34 Persistent mood [affective] disorders	0.000	0.998	0.002
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.998	0.002
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.998	0.002
F39 Unspecified mood [affective] disorder	0.000	0.998	0.002
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.002	0.998	0.000
C18.5 Splenic flexure	0.002	0.998	0.000
H26.4 After-cataract	0.000	0.998	0.002
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.002	0.998	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.002	0.998	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.002	0.998	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.002	0.998	0.000
Z97.4 Presence of external hearing-aid	0.002	0.998	0.000
F32 Depressive episode	0.000	0.998	0.002
C18.8 Overlapping lesion of colon	0.002	0.998	0.000
S82.11 Fracture of upper end of tibia (open)	0.002	0.998	0.000
N21.0 Calculus in bladder	0.002	0.998	0.000
S82.0 Fracture of patella	0.002	0.998	0.000
F30.0 Hypomania	0.000	0.998	0.002
S82.70 Multiple fractures of lower leg (closed)	0.002	0.998	0.000
D03.9 Melanoma in situ, unspecified	0.002	0.998	0.000
D03.8 Melanoma in situ of other sites	0.002	0.998	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.002	0.998	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.002	0.998	0.000
D03.0 Melanoma in situ of lip	0.002	0.998	0.000
S52.01 Fracture of upper end of ulna (open)	0.000	0.998	0.002
I73.9 Peripheral vascular disease, unspecified	0.000	0.998	0.002
O34.2 Maternal care due to uterine scar from previous surgery	0.002	0.998	0.000
S82.71 Multiple fractures of lower leg (open)	0.002	0.998	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.002	0.998	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.002	0.998	0.000
F30.9 Manic episode, unspecified	0.000	0.998	0.002
F30.8 Other manic episodes	0.000	0.998	0.002
F30.2 Mania with psychotic symptoms	0.000	0.998	0.002
F30.1 Mania without psychotic symptoms	0.000	0.998	0.002
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.998	0.002
S32.50 Fracture of pubis (closed)	0.002	0.998	0.000
D03.5 Melanoma in situ of trunk	0.002	0.998	0.000
S82.31 Fracture of lower end of tibia (open)	0.002	0.998	0.000
S82.5 Fracture of medial malleolus	0.002	0.998	0.000
I73 Other peripheral vascular diseases	0.000	0.998	0.002
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.998	0.002
F34.8 Other persistent mood [affective] disorders	0.000	0.998	0.002
F34.1 Dysthymia	0.000	0.998	0.002
F34.0 Cyclothymia	0.000	0.998	0.002
F38.8 Other specified mood [affective] disorders	0.000	0.998	0.002
F38.1 Other recurrent mood [affective] disorders	0.000	0.998	0.002
F38.0 Other single mood [affective] disorders	0.000	0.998	0.002
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.998	0.002
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.002	0.998	0.000
S82.4 Fracture of fibula alone	0.001	0.998	0.000
H66.3 Other chronic suppurative otitis media	0.002	0.998	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
F32.8 Other depressive episodes	0.000	0.998	0.002
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.998	0.002
S82.01 Fracture of patella (open)	0.001	0.998	0.000
F32.0 Mild depressive episode	0.000	0.998	0.002
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.000	0.998	0.002
C18.3 Hepatic flexure	0.001	0.998	0.000
S82.2 Fracture of shaft of tibia	0.001	0.998	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
C18.6 Descending colon	0.001	0.998	0.000
H66.9 Otitis media, unspecified	0.002	0.998	0.000
O20.0 Threatened abortion	0.000	0.998	0.002
T23 Burn and corrosion of wrist and hand	0.002	0.998	0.000
T23.3 Burn of third degree of wrist and hand	0.001	0.998	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.001	0.998	0.000
T21 Burn and corrosion of trunk	0.001	0.998	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.002	0.998	0.000
G62.8 Other specified polyneuropathies	0.000	0.998	0.002
S82.6 Fracture of lateral malleolus	0.001	0.998	0.000
S82.51 Fracture of medial malleolus (open)	0.001	0.998	0.000
C18.4 Transverse colon	0.001	0.998	0.000
F43.0 Acute stress reaction	0.001	0.998	0.000
I73.8 Other specified peripheral vascular diseases	0.000	0.998	0.001
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.998	0.001
N31.8 Other neuromuscular dysfunction of bladder	0.002	0.998	0.000
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.001	0.998	0.000
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.001	0.998	0.000
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.001	0.998	0.000
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.001	0.998	0.000
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.001	0.998	0.000
S82.41 Fracture of fibula alone (open)	0.001	0.998	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.998	0.001
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.998	0.001
T21.3 Burn of third degree of trunk	0.001	0.998	0.000
T21.2 Burn of second degree of trunk	0.001	0.998	0.000
T20 Burn and corrosion of head and neck	0.001	0.998	0.000
C18.7 Sigmoid colon	0.001	0.999	0.000
F43.9 Reaction to severe stress, unspecified	0.001	0.999	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.999	0.001
M54.9 Dorsalgia, unspecified	0.000	0.999	0.001
T23.2 Burn of second degree of wrist and hand	0.001	0.999	0.000
O64.1 Obstructed labour due to breech presentation	0.001	0.999	0.000
T20.1 Burn of first degree of head and neck	0.001	0.999	0.000
E23.2 Diabetes insipidus	0.000	0.999	0.001
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.001	0.999	0.000
T23.7 Corrosion of third degree of wrist and hand	0.001	0.999	0.000
T23.6 Corrosion of second degree of wrist and hand	0.001	0.999	0.000
T23.5 Corrosion of first degree of wrist and hand	0.001	0.999	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.001	0.999	0.000
T23.1 Burn of first degree of wrist and hand	0.001	0.999	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.001	0.999	0.000
Z97.0 Presence of artificial eye	0.001	0.999	0.000
H66 Suppurative and unspecified otitis media	0.001	0.999	0.000
T21.7 Corrosion of third degree of trunk	0.001	0.999	0.000
T21.6 Corrosion of second degree of trunk	0.001	0.999	0.000
T21.5 Corrosion of first degree of trunk	0.001	0.999	0.000
T21.4 Corrosion of unspecified degree of trunk	0.001	0.999	0.000
T21.1 Burn of first degree of trunk	0.001	0.999	0.000
T21.0 Burn of unspecified degree of trunk	0.001	0.999	0.000
M84 Disorders of continuity of bone	0.001	0.999	0.000
T25 Burn and corrosion of ankle and foot	0.001	0.999	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.001	0.999	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.001	0.999	0.000
N21.1 Calculus in urethra	0.001	0.999	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
S82.00 Fracture of patella (closed)	0.001	0.999	0.000
S82.61 Fracture of lateral malleolus (open)	0.001	0.999	0.000
D07.5 Prostate	0.001	0.999	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.001	0.999	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.999	0.001
S80-S89 Injuries to the knee and lower leg	0.001	0.999	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.001	0.999	0.000
G50.0 Trigeminal neuralgia	0.000	0.999	0.001
M84.0 Malunion of fracture	0.001	0.999	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.000	0.999	0.001
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.000	0.999	0.001
M54.92 Dorsalgia, unspecified (Cervical region)	0.000	0.999	0.001
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.000	0.999	0.001
S22.30 Fracture of rib (closed)	0.001	0.999	0.000
F43.2 Adjustment disorders	0.001	0.999	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.000	0.999	0.001
T20.7 Corrosion of third degree of head and neck	0.001	0.999	0.000
T20.6 Corrosion of second degree of head and neck	0.001	0.999	0.000
T20.5 Corrosion of first degree of head and neck	0.001	0.999	0.000
T20.4 Corrosion of unspecified degree of head and neck	0.001	0.999	0.000
T20.3 Burn of third degree of head and neck	0.001	0.999	0.000
T20.2 Burn of second degree of head and neck	0.001	0.999	0.000
T20.0 Burn of unspecified degree of head and neck	0.001	0.999	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.000	0.999	0.001
E55.9 Vitamin D deficiency, unspecified	0.001	0.999	0.000
H90.2 Conductive hearing loss, unspecified	0.000	0.999	0.001
I78.1 Naevus, nonneoplastic	0.000	0.999	0.001
Z03.1 Observation for suspected malignant neoplasm	0.000	0.999	0.001
Z29.2 Other prophylactic chemotherapy	0.000	0.999	0.001
S82.21 Fracture of shaft of tibia (open)	0.001	0.999	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.001	0.999	0.000
H70.9 Mastoiditis, unspecified	0.001	0.999	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.001	0.999	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.999	0.001
J84 Other interstitial pulmonary diseases	0.000	0.999	0.001
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.001	0.999	0.000
C18.2 Ascending colon	0.001	0.999	0.000
H66.4 Suppurative otitis media, unspecified	0.001	0.999	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.001	0.999	0.000
H66.0 Acute suppurative otitis media	0.001	0.999	0.000
R52.9 Pain, unspecified	0.001	0.999	0.000
S09.9 Unspecified injury of head	0.000	0.999	0.001
F43 Reaction to severe stress, and adjustment disorders	0.001	0.999	0.000
S86 Injury of muscle and tendon at lower leg level	0.001	0.999	0.000
M54.22 Cervicalgia (Cervical region)	0.000	0.999	0.001
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.999	0.001
M84.9 Disorder of continuity of bone, unspecified	0.001	0.999	0.000
M84.8 Other disorders of continuity of bone	0.001	0.999	0.000
M84.3 Stress fracture, not elsewhere classified	0.001	0.999	0.000
M84.2 Delayed union of fracture	0.001	0.999	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
T25.7 Corrosion of third degree of ankle and foot	0.001	0.999	0.000
T25.6 Corrosion of second degree of ankle and foot	0.001	0.999	0.000
T25.5 Corrosion of first degree of ankle and foot	0.001	0.999	0.000
T25.4 Corrosion of unspecified degree of ankle and foot	0.001	0.999	0.000
T25.3 Burn of third degree of ankle and foot	0.001	0.999	0.000
T25.2 Burn of second degree of ankle and foot	0.001	0.999	0.000
T25.1 Burn of first degree of ankle and foot	0.001	0.999	0.000
T25.0 Burn of unspecified degree of ankle and foot	0.001	0.999	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.999	0.001
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.000	0.999	0.001
H25.1 Senile nuclear cataract	0.000	0.999	0.001
J39.2 Other diseases of pharynx	0.001	0.999	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.001	0.999	0.000
S89.8 Other specified injuries of lower leg	0.001	0.999	0.000
S88 Traumatic amputation of lower leg	0.001	0.999	0.000
S87 Crushing injury of lower leg	0.001	0.999	0.000
S85 Injury of blood vessels at lower leg level	0.001	0.999	0.000
S84 Injury of nerves at lower leg level	0.001	0.999	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.999	0.001
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M54.94 Dorsalgia, unspecified (Thoracic region)	0.000	0.999	0.001
M84.09 Malunion of fracture (Site unspecified)	0.001	0.999	0.000
M84.08 Malunion of fracture (Other)	0.001	0.999	0.000
M84.06 Malunion of fracture (Lower leg)	0.001	0.999	0.000
M84.04 Malunion of fracture (Hand)	0.001	0.999	0.000
M84.02 Malunion of fracture (Upper arm)	0.001	0.999	0.000
M84.01 Malunion of fracture (Shoulder region)	0.001	0.999	0.000
M84.00 Malunion of fracture (Multiple sites)	0.001	0.999	0.000
M84.4 Pathological fracture, not elsewhere classified	0.001	0.999	0.000
R07.2 Precordial pain	0.000	0.999	0.001
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.001	0.999	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.999	0.001
V17.4 Driver injured in traffic accident	0.001	0.999	0.000
H02.0 Entropion and trichiasis of eyelid	0.001	0.999	0.000
N21 Calculus of lower urinary tract	0.001	0.999	0.000
R12 Heartburn	0.000	0.999	0.001
M84.07 Malunion of fracture (Ankle and foot)	0.001	0.999	0.000
M84.03 Malunion of fracture (Forearm)	0.001	0.999	0.000
E23.6 Other disorders of pituitary gland	0.000	0.999	0.001
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.999	0.001
E23.1 Drug-induced hypopituitarism	0.000	0.999	0.001
F43.1 Posttraumatic stress disorder	0.001	0.999	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.999	0.001
J84.8 Other specified interstitial pulmonary diseases	0.000	0.999	0.001
J84.0 Alveolar and parietoalveolar conditions	0.000	0.999	0.001
O75.7 Vaginal delivery following previous Caesarean section	0.001	0.999	0.000
R30.0 Dysuria	0.000	0.999	0.001
S51.8 Open wound of other parts of forearm	0.001	0.999	0.000
S51.0 Open wound of elbow	0.001	0.999	0.000
S83.7 Injury to multiple structures of knee	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations