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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs35690877
log Bayes Factor = 11.6354
Chromosome 3   position 161,772,583  (GRCh37) Explore rs35690877 on Ensembl!
Variant rs35690877 is part of Cluster X0196

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E11.3 With ophthalmic complications
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E11.4 With neurological complications
0.000 0.001 0.999
E11.2 With renal complications
0.000 0.020 0.980
E11.5 With peripheral circulatory complications
0.000 0.025 0.975
E10.3 With ophthalmic complications
0.000 0.070 0.930
E10.4 With neurological complications
0.000 0.076 0.924
E11.0 With coma
0.000 0.131 0.869
E10.6 With other specified complications
0.000 0.139 0.861
E10.2 With renal complications
0.000 0.151 0.849
E11.9 Without complications
0.000 0.166 0.834
E10.5 With peripheral circulatory complications
0.000 0.188 0.812
E14 Unspecified diabetes mellitus
0.000 0.194 0.806
E11.8 With unspecified complications
0.000 0.246 0.754
E11.6 With other specified complications
0.000 0.252 0.748
E11.7 With multiple complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E10.0 With coma
0.000 0.300 0.700
E14.3 With ophthalmic complications
0.000 0.355 0.645
E14.6 With other specified complications
0.000 0.365 0.635
E14.9 Without complications
0.000 0.394 0.606
E14.4 With neurological complications
0.000 0.395 0.605
E13 Other specified diabetes mellitus
0.000 0.406 0.594
E14.1 With ketoacidosis
0.000 0.407 0.593
E14.7 With multiple complications
0.000 0.422 0.578
E14.0 With coma
0.000 0.422 0.578
E14.2 Withrenal complications
0.000 0.424 0.576
F31 Bipolar affective disorder
0.000 0.446 0.554
E10.8 With unspecified complications
0.000 0.455 0.545
E14.5 With peripheral circulatory complications
0.000 0.456 0.544
F30-F39 Mood [affective] disorders
0.000 0.465 0.535
F33 Recurrent depressive disorder
0.000 0.469 0.531
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.000 0.477 0.523
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E11.1 With ketoacidosis
0.000 0.491 0.509
F31.0 Bipolar affective disorder, current episode hypomanic
0.000 0.507 0.493
F31.7 Bipolar affective disorder, currently in remission
0.000 0.511 0.489
E14.8 With unspecified complications
0.000 0.512 0.487
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.000 0.514 0.486
F31.9 Bipolar affective disorder, unspecified
0.000 0.515 0.485
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.000 0.519 0.481
F33.1 Recurrent depressive disorder, current episode moderate
0.000 0.520 0.480
F33.0 Recurrent depressive disorder, current episode mild
0.000 0.520 0.480
F33.9 Recurrent depressive disorder, unspecified
0.000 0.541 0.459
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.000 0.550 0.450
F31.6 Bipolar affective disorder, current episode mixed
0.000 0.562 0.438
E13.8 With unspecified complications
0.000 0.574 0.426
E13.7 With multiple complications
0.000 0.574 0.426
E13.6 With other specified complications
0.000 0.574 0.426
E13.5 With peripheral circulatory complications
0.000 0.574 0.426
E13.4 With neurological complications
0.000 0.574 0.426
E13.2 With renal complications
0.000 0.574 0.426
E13.1 With ketoacidosis
0.000 0.574 0.426
E13.0 With coma
0.000 0.574 0.426
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.000 0.578 0.421
E10.1 With ketoacidosis
0.000 0.579 0.421
F31.8 Other bipolar affective disorders
0.000 0.587 0.413
E13.3 With ophthalmic complications
0.000 0.587 0.412
F32 Depressive episode
0.000 0.587 0.413
F39 Unspecified mood [affective] disorder
0.000 0.594 0.406
F34 Persistent mood [affective] disorders
0.000 0.599 0.400
F38 Other mood [affective] disorders
0.000 0.616 0.384
F33.4 Recurrent depressive disorder, currently in remission
0.000 0.619 0.381
F30 Manic episode
0.000 0.627 0.373
F33.8 Other recurrent depressive disorders
0.000 0.635 0.365
F32.2 Severe depressive episode without psychotic symptoms
0.000 0.636 0.364
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.000 0.641 0.359
F32.8 Other depressive episodes
0.000 0.654 0.346
E13.9 Without complications
0.000 0.676 0.324
F34.1 Dysthymia
0.000 0.679 0.320
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.000 0.687 0.313
F30.0 Hypomania
0.000 0.697 0.303
F32.9 Depressive episode, unspecified
0.000 0.708 0.292
F34.9 Persistent mood [affective] disorder, unspecified
0.000 0.713 0.287
F34.8 Other persistent mood [affective] disorders
0.000 0.713 0.287
F30.2 Mania with psychotic symptoms
0.000 0.713 0.287
F32.1 Moderate depressive episode
0.000 0.715 0.285
F38.8 Other specified mood [affective] disorders
0.000 0.725 0.275
F38.1 Other recurrent mood [affective] disorders
0.000 0.725 0.275
F38.0 Other single mood [affective] disorders
0.000 0.725 0.275
F30.8 Other manic episodes
0.000 0.732 0.267
F34.0 Cyclothymia
0.000 0.736 0.264
F30.1 Mania without psychotic symptoms
0.000 0.747 0.253
H36.0 Diabetic retinopathy
0.000 0.763 0.237
F32.0 Mild depressive episode
0.000 0.766 0.234
F32.3 Severe depressive episode with psychotic symptoms
0.000 0.798 0.201
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.804 0.196
E20-E35 Disorders of other endocrine glands
0.000 0.814 0.186
F30.9 Manic episode, unspecified
0.000 0.817 0.183
E23 Hypofunction and other disorders of pituitary gland
0.000 0.823 0.177
E23.0 Hypopituitarism
0.000 0.824 0.176
E27 Other disorders of adrenal gland
0.000 0.831 0.169
E28 Ovarian dysfunction
0.000 0.834 0.166
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.837 0.163
E20 Hypoparathyroidism
0.000 0.852 0.147
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.857 0.143
E28.3 Primary ovarian failure
0.000 0.858 0.142
E65-E68 Obesity and other hyperalimentation
0.000 0.859 0.141
E29 Testicular dysfunction
0.000 0.860 0.140
E28.2 Polycystic ovarian syndrome
0.000 0.863 0.137
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.867 0.133
E32 Diseases of thymus
0.000 0.867 0.133
E31 Polyglandular dysfunction
0.000 0.867 0.133
E30 Disorders of puberty, not elsewhere classified
0.000 0.867 0.133
E24 Cushing's syndrome
0.000 0.867 0.133
E27.1 Primary adrenocortical insufficiency
0.000 0.868 0.132
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.869 0.131
E23.2 Diabetes insipidus
0.000 0.869 0.131
E27.8 Other specified disorders of adrenal gland
0.000 0.870 0.130
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.873 0.127
E23.1 Drug-induced hypopituitarism
0.000 0.873 0.127
E23.6 Other disorders of pituitary gland
0.000 0.876 0.124
E25 Adrenogenital disorders
0.000 0.876 0.124
E40-E46 Malnutrition
0.000 0.877 0.123
E27.5 Adrenomedullary hyperfunction
0.000 0.879 0.121
E27.0 Other adrenocortical overactivity
0.000 0.879 0.121
E20.9 Hypoparathyroidism, unspecified
0.000 0.880 0.120
E28.9 Ovarian dysfunction, unspecified
0.000 0.881 0.119
E28.8 Other ovarian dysfunction
0.000 0.881 0.119
E28.1 Androgen excess
0.000 0.881 0.119
E28.0 Oestrogen excess
0.000 0.881 0.119
E65 Localised adiposity
0.000 0.885 0.115
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.885 0.115
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.892 0.108
E29.1 Testicular hypofunction
0.000 0.893 0.107
E20.8 Other hypoparathyroidism
0.000 0.894 0.106
E20.1 Pseudohypoparathyroidism
0.000 0.894 0.106
E20.0 Idiopathic hypoparathyroidism
0.000 0.894 0.106
E16 Other disorders of pancreatic internal secretion
0.000 0.895 0.105
H36 Retinal disorders in diseases classified elsewhere
0.000 0.897 0.103
E15 Nondiabetic hypoglycaemic coma
0.000 0.897 0.103
E24.9 Cushing's syndrome, unspecified
0.000 0.898 0.102
E00-E07 Disorders of thyroid gland
0.000 0.899 0.101
E67 Other hyperalimentation
0.000 0.899 0.101
E68 Sequelae of hyperalimentation
0.000 0.899 0.101
E29.9 Testicular dysfunction, unspecified
0.000 0.899 0.101
E29.8 Other testicular dysfunction
0.000 0.899 0.101
E29.0 Testicular hyperfunction
0.000 0.899 0.101
E24.0 Pituitary-dependent Cushing's disease
0.000 0.902 0.098
E27.2 Addisonian crisis
0.000 0.903 0.097
E26 Hyperaldosteronism
0.000 0.903 0.097
E21.2 Other hyperparathyroidism
0.000 0.903 0.097
E30.9 Disorder of puberty, unspecified
0.000 0.904 0.096
E30.8 Other disorders of puberty
0.000 0.904 0.096
E30.1 Precocious puberty
0.000 0.904 0.096
E30.0 Delayed puberty
0.000 0.904 0.096
E31.9 Polyglandular dysfunction, unspecified
0.000 0.904 0.096
E31.8 Other polyglandular dysfunction
0.000 0.904 0.096
E31.1 Polyglandular hyperfunction
0.000 0.904 0.096
E31.0 Autoimmune polyglandular failure
0.000 0.904 0.096
E32.9 Disease of thymus, unspecified
0.000 0.904 0.096
E32.8 Other diseases of thymus
0.000 0.904 0.096
E32.1 Abscess of thymus
0.000 0.904 0.096
E32.0 Persistent hyperplasia of thymus
0.000 0.904 0.096
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.904 0.096
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.904 0.096
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.904 0.096
E24.8 Other Cushing's syndrome
0.000 0.904 0.096
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.904 0.096
E24.3 Ectopic ACTH syndrome
0.000 0.904 0.096
E24.1 Nelson's syndrome
0.000 0.904 0.096
E34 Other endocrine disorders
0.000 0.905 0.095
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.906 0.094
E27.9 Disorder of adrenal gland, unspecified
0.000 0.910 0.090
E25.9 Adrenogenital disorder, unspecified
0.000 0.911 0.089
E25.8 Other adrenogenital disorders
0.000 0.911 0.089
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.911 0.088
E45 Retarded development following protein-energy malnutrition
0.000 0.911 0.088
E43 Unspecified severe protein-energy malnutrition
0.000 0.911 0.088
E42 Marasmic kwashiorkor
0.000 0.911 0.088
E41 Nutritional marasmus
0.000 0.911 0.088
E40 Kwashiorkor
0.000 0.911 0.088
E21.4 Other specified disorders of parathyroid gland
0.000 0.911 0.088
E21.3 Hyperparathyroidism, unspecified
0.000 0.915 0.085
E24.2 Drug-induced Cushing's syndrome
0.000 0.915 0.085
E50-E64 Other nutritional deficiencies
0.000 0.916 0.084
E21.0 Primary hyperparathyroidism
0.000 0.917 0.083
E03 Other hypothyroidism
0.000 0.918 0.082
E16.1 Other hypoglycaemia
0.000 0.918 0.082
E16.2 Hypoglycaemia, unspecified
0.000 0.919 0.081
E66 Obesity
0.000 0.919 0.081
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.921 0.079
E04 Other non-toxic goitre
0.000 0.921 0.079
E03.8 Other specified hypothyroidism
0.000 0.924 0.076
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.924 0.076
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.924 0.076
E16.4 Abnormal secretion of gastrin
0.000 0.924 0.076
E16.3 Increased secretion of glucagon
0.000 0.924 0.076
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.926 0.074
E23.7 Disorder of pituitary gland, unspecified
0.001 0.926 0.073
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.927 0.073
E00 Congenital iodine-deficiency syndrome
0.000 0.927 0.073
E67.8 Other specified hyperalimentation
0.000 0.927 0.073
E67.3 Hypervitaminosis D
0.000 0.927 0.073
E67.2 Megavitamin-B6 syndrome
0.000 0.927 0.073
E67.1 Hypercarotenaemia
0.000 0.927 0.073
E67.0 Hypervitaminosis A
0.000 0.927 0.073
E46 Unspecified protein-energy malnutrition
0.000 0.929 0.071
E04.2 Non-toxic multinodular goitre
0.000 0.929 0.071
E66.0 Obesity due to excess calories
0.000 0.930 0.070
E26.8 Other hyperaldosteronism
0.000 0.930 0.069
E26.1 Secondary hyperaldosteronism
0.000 0.930 0.069
E34.5 Androgen resistance syndrome
0.000 0.932 0.068
E34.4 Constitutional tall stature
0.000 0.932 0.068
E34.3 Short stature, not elsewhere classified
0.000 0.932 0.068
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.932 0.068
E34.1 Other hypersecretion of intestinal hormones
0.000 0.932 0.068
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.934 0.066
E06 Thyroiditis
0.000 0.934 0.066
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.936 0.064
E44.1 Mild protein-energy malnutrition
0.000 0.936 0.064
E44.0 Moderate protein-energy malnutrition
0.000 0.936 0.064
E34.9 Endocrine disorder, unspecified
0.000 0.939 0.061
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.939 0.060
E63 Other nutritional deficiencies
0.000 0.939 0.060
E56 Other vitamin deficiencies
0.000 0.939 0.060
E50 Vitamin A deficiency
0.000 0.939 0.060
E60 Dietary zinc deficiency
0.000 0.939 0.060
E59 Dietary selenium deficiency
0.000 0.939 0.060
E54 Ascorbic acid deficiency
0.000 0.939 0.060
E52 Niacin deficiency [pellagra]
0.000 0.939 0.060
E04.9 Non-toxic goitre, unspecified
0.000 0.940 0.060
E51 Thiamine deficiency
0.000 0.940 0.060
E34.8 Other specified endocrine disorders
0.000 0.940 0.060
E03.5 Myxoedema coma
0.000 0.941 0.059
E03.4 Atrophy of thyroid (acquired)
0.000 0.941 0.059
E03.3 Postinfectious hypothyroidism
0.000 0.941 0.059
E03.1 Congenital hypothyroidism without goitre
0.000 0.941 0.059
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.941 0.059
E55 Vitamin D deficiency
0.000 0.941 0.059
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.941 0.059
E66.1 Drug-induced obesity
0.000 0.942 0.058
E26.9 Hyperaldosteronism, unspecified
0.000 0.943 0.056
E04.8 Other specified non-toxic goitre
0.000 0.943 0.057
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.944 0.056
E66.9 Obesity, unspecified
0.000 0.944 0.056
E34.0 Carcinoid syndrome
0.000 0.945 0.055
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.945 0.055
E04.0 Non-toxic diffuse goitre
0.000 0.945 0.054
E58 Dietary calcium deficiency
0.000 0.946 0.054
E26.0 Primary hyperaldosteronism
0.000 0.946 0.053
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.947 0.052
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.947 0.052
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.947 0.052
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.947 0.052
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.947 0.052
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.947 0.052
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.947 0.052
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.947 0.052
E53 Deficiency of other B group vitamins
0.000 0.949 0.051
E07 Other disorders of thyroid
0.000 0.952 0.048
E06.4 Drug-induced thyroiditis
0.000 0.952 0.048
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.952 0.048
E06.0 Acute thyroiditis
0.000 0.952 0.048
E06.9 Thyroiditis, unspecified
0.000 0.953 0.047
E06.5 Other chronic thyroiditis
0.000 0.953 0.047
E06.3 Autoimmune thyroiditis
0.000 0.953 0.047
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.954 0.046
I21.1 Acute transmural myocardial infarction of inferior wall
0.046 0.954 0.000
E22 Hyperfunction of pituitary gland
0.001 0.956 0.043
E50.9 Vitamin A deficiency, unspecified
0.000 0.956 0.043
E50.8 Other manifestations of vitamin A deficiency
0.000 0.956 0.043
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.956 0.043
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.956 0.043
E50.5 Vitamin A deficiency with night blindness
0.000 0.956 0.043
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.956 0.043
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.956 0.043
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.956 0.043
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.956 0.043
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.956 0.043
E56.9 Vitamin deficiency, unspecified
0.000 0.956 0.043
E56.8 Deficiency of other vitamins
0.000 0.956 0.043
E56.1 Deficiency of vitamin K
0.000 0.956 0.043
E56.0 Deficiency of vitamin E
0.000 0.956 0.043
E63.9 Nutritional deficiency, unspecified
0.000 0.956 0.043
E63.8 Other specified nutritional deficiencies
0.000 0.956 0.043
E63.1 Imbalance of constituents of food intake
0.000 0.956 0.043
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.956 0.043
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.956 0.043
E64.8 Sequelae of other nutritional deficiencies
0.000 0.956 0.043
E64.3 Sequelae of rickets
0.000 0.956 0.043
E64.2 Sequelae of vitamin C deficiency
0.000 0.956 0.043
E64.1 Sequelae of vitamin A deficiency
0.000 0.956 0.043
E64.0 Sequelae of protein-energy malnutrition
0.000 0.956 0.043
E51.9 Thiamine deficiency, unspecified
0.000 0.957 0.043
E51.8 Other manifestations of thiamine deficiency
0.000 0.957 0.043
E51.1 Beriberi
0.000 0.957 0.043
E51.2 Wernicke's encephalopathy
0.000 0.957 0.043
E06.1 Subacute thyroiditis
0.000 0.957 0.043
E61 Deficiency of other nutrient elements
0.000 0.957 0.043
E55.0 Rickets, active
0.000 0.958 0.042
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.959 0.041
E05.5 Thyroid crisis or storm
0.000 0.959 0.040
E05.4 Thyrotoxicosis factitia
0.000 0.959 0.040
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.959 0.040
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.959 0.040
E55.9 Vitamin D deficiency, unspecified
0.000 0.959 0.041
E03.9 Hypothyroidism, unspecified
0.000 0.961 0.039
E53.1 Pyridoxine deficiency
0.000 0.963 0.036
E53.0 Riboflavin deficiency
0.000 0.963 0.036
E07.1 Dyshormogenetic goitre
0.000 0.965 0.035
E07.0 Hypersecretion of calcitonin
0.000 0.965 0.035
E05.8 Other thyrotoxicosis
0.000 0.965 0.035
E04.1 Non-toxic single thyroid nodule
0.000 0.966 0.034
E53.9 Vitamin B deficiency, unspecified
0.000 0.967 0.032
E53.8 Deficiency of other specified B group vitamins
0.000 0.968 0.032
E22.9 Hyperfunction of pituitary gland, unspecified
0.001 0.968 0.031
E22.8 Other hyperfunction of pituitary gland
0.001 0.968 0.031
E61.9 Deficiency of nutrient element, unspecified
0.000 0.969 0.031
E61.8 Deficiency of other specified nutrient elements
0.000 0.969 0.031
E61.7 Deficiency of multiple nutrient elements
0.000 0.969 0.031
E61.6 Vanadium deficiency
0.000 0.969 0.031
E61.5 Molybdenum deficiency
0.000 0.969 0.031
E61.4 Chromium deficiency
0.000 0.969 0.031
E61.3 Manganese deficiency
0.000 0.969 0.031
E61.0 Copper deficiency
0.000 0.969 0.031
Q80-Q89 Other congenital malformations
0.028 0.971 0.000
Q82 Other congenital malformations of skin
0.028 0.972 0.000
Q63.0 Accessory kidney
0.027 0.973 0.000
E07.8 Other specified disorders of thyroid
0.000 0.973 0.026
Q82.8 Other specified congenital malformations of skin
0.026 0.974 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.026 0.974 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.026 0.974 0.000
E61.2 Magnesium deficiency
0.000 0.975 0.025
E07.9 Disorder of thyroid, unspecified
0.000 0.975 0.025
Q66 Congenital deformities of feet
0.025 0.975 0.000
Q63 Other congenital malformations of kidney
0.025 0.975 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.024 0.976 0.000
Q60-Q64 Congenital malformations of the urinary system
0.024 0.976 0.000
Q66.8 Other congenital deformities of feet
0.024 0.976 0.000
E22.0 Acromegaly and pituitary gigantism
0.001 0.976 0.023
Q83 Congenital malformations of breast
0.023 0.977 0.000
Q82.5 Congenital nonneoplastic naevus
0.023 0.977 0.000
Q82.2 Mastocytosis
0.023 0.977 0.000
Q65 Congenital deformities of hip
0.023 0.977 0.000
E61.1 Iron deficiency
0.000 0.977 0.023
Q85 Phakomatoses, not elsewhere classified
0.023 0.977 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.022 0.978 0.000
Q87.4 Marfan's syndrome
0.022 0.978 0.000
Q89 Other congenital malformations, not elsewhere classified
0.022 0.978 0.000
Q66.2 Metatarsus varus
0.021 0.979 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.021 0.979 0.000
Q84 Other congenital malformations of integument
0.021 0.979 0.000
Q81 Epidermolysis bullosa
0.021 0.979 0.000
Q80 Congenital ichthyosis
0.021 0.979 0.000
Q82.9 Congenital malformation of skin, unspecified
0.020 0.980 0.000
Q82.4 Ectodermal dysplasia (anhidrotic)
0.020 0.980 0.000
Q82.3 Incontinentia pigmenti
0.020 0.980 0.000
Q82.1 Xeroderma pigmentosum
0.020 0.980 0.000
Q82.0 Hereditary lymphoedema
0.020 0.980 0.000
Q83.1 Accessory breast
0.020 0.980 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.000 0.980 0.020
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.020 0.980 0.000
Q65.8 Other congenital deformities of hip
0.020 0.980 0.000
Q00-Q07 Congenital malformations of the nervous system
0.020 0.980 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.019 0.981 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.019 0.981 0.000
Q85.0 Neurofibromatosis (nonmalignant)
0.019 0.981 0.000
Q63.8 Other specified congenital malformations of kidney
0.019 0.981 0.000
Q65.1 Congenital dislocation of hip, bilateral
0.019 0.981 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.019 0.981 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.981 0.019
Q66.3 Other congenital varus deformities of feet
0.019 0.981 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.018 0.981 0.000
Q75 Other congenital malformations of skull and face bones
0.018 0.981 0.000
Q73 Reduction defects of unspecified limb
0.018 0.981 0.000
Q72 Reduction defects of lower limb
0.018 0.981 0.000
Q71 Reduction defects of upper limb
0.018 0.981 0.000
Q70 Syndactyly
0.018 0.981 0.000
Q69 Polydactyly
0.018 0.981 0.000
Q35-Q37 Cleft lip and cleft palate
0.018 0.982 0.000
Q79.6 Ehlers-Danlos syndrome
0.018 0.982 0.000
Q63.2 Ectopic kidney
0.018 0.982 0.000
Q68 Other congenital musculoskeletal deformities
0.018 0.982 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.018 0.982 0.000
Q83.3 Accessory nipple
0.018 0.982 0.000
Q66.9 Congenital deformity of feet, unspecified
0.018 0.982 0.000
Q66.6 Other congenital valgus deformities of feet
0.018 0.982 0.000
Q66.5 Congenital pes planus
0.018 0.982 0.000
Q66.4 Talipes calcaneovalgus
0.018 0.982 0.000
Q66.1 Talipes calcaneovarus
0.018 0.982 0.000
Q63.9 Congenital malformation of kidney, unspecified
0.018 0.982 0.000
Q63.3 Hyperplastic and giant kidney
0.018 0.982 0.000
Q74 Other congenital malformations of limb(s)
0.018 0.982 0.000
Q79.8 Other congenital malformations of musculoskeletal system
0.018 0.982 0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified
0.018 0.982 0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes
0.018 0.982 0.000
Q87.3 Congenital malformation syndromes involving early overgrowth
0.018 0.982 0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs
0.018 0.982 0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature
0.018 0.982 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.017 0.982 0.000
K50.0 Crohn's disease of small intestine
0.017 0.983 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.017 0.983 0.000
Q89.2 Congenital malformations of other endocrine glands
0.017 0.983 0.000
Q85.8 Other phakomatoses, not elsewhere classified
0.017 0.983 0.000
Q60.2 Renal agenesis, unspecified
0.017 0.983 0.000
Q83.9 Congenital malformation of breast, unspecified
0.017 0.983 0.000
Q83.2 Absent nipple
0.017 0.983 0.000
Q83.0 Congenital absence of breast with absent nipple
0.017 0.983 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.983 0.017
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.983 0.017
Q78 Other osteochondrodysplasias
0.017 0.983 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.017 0.983 0.000
Q66.0 Talipes equinovarus
0.017 0.983 0.000
Q65.9 Congenital deformity of hip, unspecified
0.016 0.983 0.000
Q65.6 Unstable hip
0.016 0.983 0.000
Q65.5 Congenital subluxation of hip, unspecified
0.016 0.983 0.000
Q65.4 Congenital subluxation of hip, bilateral
0.016 0.983 0.000
Q65.3 Congenital subluxation of hip, unilateral
0.016 0.983 0.000
Q65.2 Congenital dislocation of hip, unspecified
0.016 0.983 0.000
Q65.0 Congenital dislocation of hip, unilateral
0.016 0.983 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.001 0.983 0.016
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance
0.016 0.983 0.000
Q85.1 Tuberous sclerosis
0.016 0.983 0.000
Z11.2 Special screening examination for other bacterial diseases
0.017 0.983 0.000
Q66.7 Pes cavus
0.016 0.984 0.000
Q62.1 Atresia and stenosis of ureter
0.016 0.984 0.000
N48.6 Balanitis xerotica obliterans
0.000 0.984 0.016
E22.1 Hyperprolactinaemia
0.001 0.984 0.015
Q79.9 Congenital malformation of musculoskeletal system, unspecified
0.016 0.984 0.000
Q79.5 Other congenital malformations of abdominal wall
0.016 0.984 0.000
Q79.4 Prune belly syndrome
0.016 0.984 0.000
Q79.3 Gastroschisis
0.016 0.984 0.000
Q79.2 Exomphalos
0.016 0.984 0.000
Q79.1 Other congenital malformations of diaphragm
0.016 0.984 0.000
Q79.0 Congenital diaphragmatic hernia
0.016 0.984 0.000
Q89.9 Congenital malformation, unspecified
0.016 0.984 0.000
Q89.8 Other specified congenital malformations
0.016 0.984 0.000
Q89.7 Multiple congenital malformations, not elsewhere classified
0.016 0.984 0.000
Q89.4 Conjoined twins
0.016 0.984 0.000
Q89.3 Situs inversus
0.016 0.984 0.000
Q89.1 Congenital malformations of adrenal gland
0.016 0.984 0.000
Q89.0 Congenital malformations of spleen
0.016 0.984 0.000
Q64 Other congenital malformations of urinary system
0.016 0.984 0.000
I69 Sequelae of cerebrovascular disease
0.000 0.984 0.016
G59.0 Diabetic mononeuropathy
0.000 0.984 0.016
I69.3 Sequelae of cerebral infarction
0.000 0.985 0.015
Q62.5 Duplication of ureter
0.015 0.985 0.000
Q03 Congenital hydrocephalus
0.015 0.985 0.000
Q76 Congenital malformations of spine and bony thorax
0.015 0.985 0.000
Q80.9 Congenital ichthyosis, unspecified
0.015 0.985 0.000
Q80.8 Other congenital ichthyosis
0.015 0.985 0.000
Q80.4 Harlequin foetus
0.015 0.985 0.000
Q80.3 Congenital bullous ichthyosiform erythroderma
0.015 0.985 0.000
Q80.2 Lamellar ichthyosis
0.015 0.985 0.000
Q80.1 X-linked ichthyosis
0.015 0.985 0.000
Q80.0 Ichthyosis vulgaris
0.015 0.985 0.000
Q81.9 Epidermolysis bullosa, unspecified
0.015 0.985 0.000
Q81.8 Other epidermolysis bullosa
0.015 0.985 0.000
Q81.2 Epidermolysis bullosa dystrophica
0.015 0.985 0.000
Q81.1 Epidermolysis bullosa letalis
0.015 0.985 0.000
Q81.0 Epidermolysis bullosa simplex
0.015 0.985 0.000
Q84.9 Congenital malformation of integument, unspecified
0.015 0.985 0.000
Q84.8 Other specified congenital malformations of integument
0.015 0.985 0.000
Q84.6 Other congenital malformations of nails
0.015 0.985 0.000
Q84.5 Enlarged and hypertrophic nails
0.015 0.985 0.000
Q84.4 Congenital leukonychia
0.015 0.985 0.000
Q84.3 Anonychia
0.015 0.985 0.000
Q84.2 Other congenital malformations of hair
0.015 0.985 0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified
0.015 0.985 0.000
Q84.0 Congenital alopecia
0.015 0.985 0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes
0.015 0.985 0.000
Q86.2 Dysmorphism due to warfarin
0.015 0.985 0.000
Q86.1 Foetal hydantoin syndrome
0.015 0.985 0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)
0.015 0.985 0.000
Q85.9 Phakomatosis, unspecified
0.015 0.985 0.000
Q07 Other congenital malformations of nervous system
0.015 0.985 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.015 0.985 0.000
N48 Other disorders of penis
0.000 0.985 0.015
Q43 Other congenital malformations of intestine
0.015 0.985 0.000
Q83.8 Other congenital malformations of breast
0.014 0.985 0.000
D86.0 Sarcoidosis of lung
0.000 0.985 0.015
K83.8 Other specified diseases of biliary tract
0.015 0.985 0.000
N48.4 Impotence of organic origin
0.000 0.985 0.015
Q62.8 Other congenital malformations of ureter
0.014 0.985 0.000
Q62.7 Congenital vesico-uretero-renal reflux
0.014 0.985 0.000
Q62.6 Malposition of ureter
0.014 0.985 0.000
Q62.4 Agenesis of ureter
0.014 0.985 0.000
Q62.3 Other obstructive defects of renal pelvis and ureter
0.014 0.985 0.000
Q62.2 Congenital megaloureter
0.014 0.985 0.000
Q62.0 Congenital hydronephrosis
0.014 0.985 0.000
Q74.1 Congenital malformation of knee
0.014 0.986 0.000
C18.4 Transverse colon
0.000 0.986 0.014
Q20-Q28 Congenital malformations of the circulatory system
0.014 0.986 0.000
Q44.6 Cystic disease of liver
0.014 0.986 0.000
Q45 Other congenital malformations of digestive system
0.014 0.986 0.000
Q06 Other congenital malformations of spinal cord
0.014 0.986 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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