TreeWAS – Variant ID: rs35955841

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
L85.9 Epidermal thickening, unspecified	0.031	0.969	0.000
H35.9 Retinal disorder, unspecified	0.023	0.977	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.977	0.023
H35.8 Other specified retinal disorders	0.023	0.977	0.000
H35 Other retinal disorders	0.023	0.977	0.000
H35.2 Other proliferative retinopathy	0.022	0.978	0.000
E78.5 Hyperlipidaemia, unspecified	0.000	0.979	0.021
T42.4 Benzodiazepines	0.000	0.979	0.021
H35.0 Background retinopathy and retinal vascular changes	0.021	0.979	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.980	0.020
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.980	0.019
H35.7 Separation of retinal layers	0.019	0.981	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.982	0.018
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.982	0.018
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.983	0.017
T42.1 Iminostilbenes	0.000	0.983	0.017
H35.4 Peripheral retinal degeneration	0.017	0.983	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.983	0.017
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.983	0.017
H35.1 Retinopathy of prematurity	0.016	0.984	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.984	0.016
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.984	0.016
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.985	0.015
T42.3 Barbiturates	0.000	0.985	0.015
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.985	0.015
T42.2 Succinimides and oxazolidinediones	0.000	0.985	0.015
T38.1 Thyroid hormones and substitutes	0.000	0.985	0.015
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.986	0.014
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.986	0.014
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.986	0.014
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.986	0.014
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.986	0.014
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.986	0.014
T44.0 Anticholinesterase agents	0.000	0.986	0.014
T45.2 Vitamins, not elsewhere classified	0.000	0.986	0.014
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.986	0.014
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.014	0.986	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.986	0.014
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.987	0.013
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.987	0.013
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.987	0.013
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.987	0.013
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.987	0.013
T45.0 Antiallergic and antiemetic drugs	0.000	0.987	0.013
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.987	0.013
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.987	0.013
T45.8 Other primarily systemic and haematological agents	0.000	0.987	0.013
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.987	0.013
T45.6 Fibrinolysis-affecting drugs	0.000	0.987	0.013
T45.4 Iron and its compounds	0.000	0.987	0.013
T45.3 Enzymes, not elsewhere classified	0.000	0.987	0.013
T45.5 Anticoagulants	0.000	0.988	0.012
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.988	0.012
T38.9 Other and unspecified hormone antagonists	0.000	0.988	0.012
T38.7 Androgens and anabolic congeners	0.000	0.988	0.012
T38.4 Oral contraceptives	0.000	0.988	0.012
T38.2 Antithyroid drugs	0.000	0.988	0.012
T38.0 Glucocorticoids and synthetic analogues	0.000	0.988	0.012
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.988	0.012
T36 Poisoning by systemic antibiotics	0.000	0.988	0.012
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.988	0.012
T42.0 Hydantoin derivatives	0.000	0.988	0.012
T38.5 Other oestrogens and progestogens	0.000	0.988	0.012
T39.4 Antirheumatics, not elsewhere classified	0.000	0.988	0.011
T39.2 Pyrazolone derivatives	0.000	0.988	0.011
T50.8 Diagnostic agents	0.000	0.989	0.011
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.989	0.011
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.989	0.011
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.989	0.010
H35.3 Degeneration of macula and posterior pole	0.011	0.989	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.989	0.010
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.990	0.010
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.990	0.010
T49.9 Topical agent, unspecified	0.000	0.990	0.010
T49.8 Other topical agents	0.000	0.990	0.010
T49.7 Dental drugs, topically applied	0.000	0.990	0.010
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.990	0.010
T49.5 Ophthalmological drugs and preparations	0.000	0.990	0.010
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.990	0.010
T49.3 Emollients, demulcents and protectants	0.000	0.990	0.010
T49.2 Local astringents and local detergents	0.000	0.990	0.010
T49.1 Antipruritics	0.000	0.990	0.010
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.010	0.990	0.000
T41.5 Therapeutic gases	0.000	0.990	0.010
T41.4 Anaesthetic, unspecified	0.000	0.990	0.010
T41.3 Local anaesthetics	0.000	0.990	0.010
T41.2 Other and unspecified general anaesthetics	0.000	0.990	0.010
T41.1 Intravenous anaesthetics	0.000	0.990	0.010
T41.0 Inhaled anaesthetics	0.000	0.990	0.010
T36.0 Penicillins	0.000	0.990	0.010
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.990	0.010
T48.4 Expectorants	0.000	0.990	0.010
T48.3 Antitussives	0.000	0.990	0.010
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.990	0.010
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.990	0.010
T48.0 Oxytocic drugs	0.000	0.990	0.010
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.990	0.010
H35.6 Retinal haemorrhage	0.009	0.990	0.000
T47.6 Antidiarrhoeal drugs	0.000	0.990	0.009
J92.0 Pleural plaque with presence of asbestos	0.009	0.991	0.000
T47.4 Other laxatives	0.000	0.991	0.009
T47.2 Stimulant laxatives	0.000	0.991	0.009
M54.36 Sciatica (Lumbar region)	0.000	0.991	0.009
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.991	0.009
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.991	0.009
T47.7 Emetics	0.000	0.991	0.009
T47.5 Digestants	0.000	0.991	0.009
T47.3 Saline and osmotic laxatives	0.000	0.991	0.009
T50.7 Analeptics and opioid receptor antagonists	0.000	0.991	0.009
T50.5 Appetite depressants	0.000	0.991	0.009
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.991	0.009
T50.1 Loop [high-ceiling] diuretics	0.000	0.991	0.009
T50.0 Mineralocorticoids and their antagonists	0.000	0.991	0.009
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.991	0.009
T36.9 Systemic antibiotic, unspecified	0.000	0.991	0.009
T36.7 Antifungal antibiotics, systemically used	0.000	0.991	0.009
T36.6 Rifamycins	0.000	0.991	0.009
T36.5 Aminoglycosides	0.000	0.991	0.009
T36.2 Chloramphenicol group	0.000	0.991	0.009
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.991	0.009
T37.5 Antiviral drugs	0.000	0.991	0.009
T37.4 Anthelminthics	0.000	0.991	0.009
T37.3 Other antiprotozoal drugs	0.000	0.991	0.009
T37.1 Antimycobacterial drugs	0.000	0.991	0.009
T37.0 Sulphonamides	0.000	0.991	0.009
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.991	0.009
T50.4 Drugs affecting uric acid metabolism	0.000	0.991	0.009
M19.04 Primary arthrosis of other joints (Hand)	0.009	0.991	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.991	0.009
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.991	0.009
T47.0 Histamine H(2)-receptor antagonists	0.000	0.991	0.008
T36.3 Macrolides	0.000	0.992	0.008
T43.6 Psychostimulants with abuse potential	0.000	0.992	0.008
T36.4 Tetracyclines	0.000	0.992	0.008
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.992	0.008
T36.8 Other systemic antibiotics	0.000	0.992	0.008
T39.0 Salicylates	0.000	0.992	0.008
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.992	0.008
T48.5 Anti-common-cold drugs	0.000	0.992	0.008
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.992	0.008
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.008	0.992	0.000
T40.2 Other opioids	0.000	0.992	0.008
M47.82 Other spondylosis (Cervical region)	0.000	0.992	0.008
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.992	0.008
H35.5 Hereditary retinal dystrophy	0.007	0.992	0.000
T43.9 Psychotropic drug, unspecified	0.000	0.992	0.008
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.992	0.008
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.992	0.008
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.008	0.992	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.992	0.007
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.007	0.993	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.007	0.993	0.000
M54.39 Sciatica (Site unspecified)	0.000	0.993	0.007
M54.3 Sciatica	0.000	0.993	0.007
S30 Superficial injury of abdomen, lower back and pelvis	0.007	0.993	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.993	0.007
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.993	0.007
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.993	0.007
T46.7 Peripheral vasodilators	0.000	0.993	0.007
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.993	0.007
J92.9 Pleural plaque without asbestos	0.007	0.993	0.000
S31 Open wound of abdomen, lower back and pelvis	0.007	0.993	0.000
J92 Pleural plaque	0.007	0.993	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.993	0.007
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.993	0.007
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.993	0.007
T40.8 Lysergide [LSD]	0.000	0.993	0.007
T40.7 Cannabis (derivatives)	0.000	0.993	0.007
T40.3 Methadone	0.000	0.993	0.007
T40.0 Opium	0.000	0.993	0.007
T46.1 Calcium-channel blockers	0.000	0.993	0.006
T40.6 Other and unspecified narcotics	0.000	0.993	0.006
G96.0 Cerebrospinal fluid leak	0.000	0.993	0.007
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.993	0.006
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.006	0.994	0.000
M54.37 Sciatica (Lumbosacral region)	0.000	0.994	0.006
Z34.0 Supervision of normal first pregnancy	0.006	0.994	0.000
M19.0 Primary arthrosis of other joints	0.006	0.994	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.006	0.994	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.994	0.006
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.006	0.994	0.000
S37 Injury of urinary and pelvic organs	0.006	0.994	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.006	0.994	0.000
S31.4 Open wound of vagina and vulva	0.006	0.994	0.000
T40.1 Heroin	0.000	0.994	0.006
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.994	0.006
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.006	0.994	0.000
K92.2 Gastro-intestinal haemorrhage, unspecified	0.000	0.994	0.006
S30.1 Contusion of abdominal wall	0.006	0.994	0.000
S36 Injury of intra-abdominal organs	0.006	0.994	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.006	0.994	0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.006	0.994	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.006	0.994	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.006	0.994	0.000
M54.35 Sciatica (Thoracolumbar region)	0.000	0.994	0.005
M54.34 Sciatica-Thoracic	0.000	0.994	0.005
M54.33 Sciatica-Cervicothoracic	0.000	0.994	0.005
M54.32 Sciatica-Cervical	0.000	0.994	0.005
M54.31 Sciatica-Occipit-atl-axl	0.000	0.994	0.005
G96.1 Disorders of meninges, not elsewhere classified	0.000	0.994	0.006
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.994	0.005
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.005	0.995	0.000
G96 Other disorders of central nervous system	0.000	0.995	0.005
S34.1 Other injury of lumbar spinal cord	0.005	0.995	0.000
S30.2 Contusion of external genital organs	0.005	0.995	0.000
L85 Other epidermal thickening	0.005	0.995	0.000
N90.4 Leukoplakia of vulva	0.000	0.995	0.005
S31.5 Open wound of other and unspecified external genital organs	0.005	0.995	0.000
S31.3 Open wound of scrotum and testes	0.005	0.995	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.000	0.995	0.005
M54.30 Sciatica (Multiple sites in spine)	0.000	0.995	0.005
C71.2 Temporal lobe	0.005	0.995	0.000
S34.2 Injury of nerve root of lumbar and sacral spine	0.005	0.995	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.005	0.995	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.005	0.995	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.005	0.995	0.000
C71 Malignant neoplasm of brain	0.005	0.995	0.000
T40.5 Cocaine	0.000	0.995	0.005
S31.1 Open wound of abdominal wall	0.005	0.995	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.000	0.995	0.005
T43.2 Other and unspecified antidepressants	0.000	0.995	0.005
S32 Fracture of lumbar spine and pelvis	0.005	0.995	0.000
C71.4 Occipital lobe	0.005	0.995	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.005	0.995	0.000
S31.2 Open wound of penis	0.005	0.995	0.000
C71.9 Brain, unspecified	0.005	0.995	0.000
S37.3 Injury of urethra	0.005	0.995	0.000
S30.0 Contusion of lower back and pelvis	0.005	0.995	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.995	0.005
C50.1 Central portion of breast	0.005	0.995	0.000
S34.8 Injury of other and unspecified nerves at abdomen, lower back and pelvis level	0.005	0.995	0.000
S34.6 Injury of peripheral nerve(s) of abdomen, lower back and pelvis	0.005	0.995	0.000
S34.5 Injury of lumbar, sacral and pelvic sympathetic nerves	0.005	0.995	0.000
S34.4 Injury of lumbosacral plexus	0.005	0.995	0.000
S34.3 Injury of cauda equina	0.005	0.995	0.000
S34.0 Concussion and oedema of lumbar spinal cord	0.005	0.995	0.000
C71.1 Frontal lobe	0.005	0.995	0.000
S32.0 Fracture of lumbar vertebra	0.005	0.995	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.995	0.005
S31.0 Open wound of lower back and pelvis	0.005	0.995	0.000
S33.1 Dislocation of lumbar vertebra	0.005	0.995	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.005	0.995	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.005	0.995	0.000
S37.2 Injury of bladder	0.005	0.995	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.005	0.995	0.000
S36.0 Injury of spleen	0.005	0.995	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.995	0.005
S37.0 Injury of kidney	0.005	0.995	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.005	0.995	0.000
M19.08 Primary arthrosis of other joints (Other)	0.005	0.995	0.000
Z34 Supervision of normal pregnancy	0.005	0.995	0.000
S37.9 Injury of unspecified pelvic organ	0.004	0.995	0.000
S37.8 Injury of other pelvic organs	0.004	0.995	0.000
S37.7 Injury of multiple pelvic organs	0.004	0.995	0.000
S37.6 Injury of uterus	0.004	0.995	0.000
S37.5 Injury of Fallopian tube	0.004	0.995	0.000
S37.4 Injury of ovary	0.004	0.995	0.000
S37.1 Injury of ureter	0.004	0.995	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.004	0.995	0.000
S33.7 Sprain and strain of other and unspecified parts of lumbar spine and pelvis	0.004	0.996	0.000
S33.6 Sprain and strain of sacro-iliac joint	0.004	0.996	0.000
S33.5 Sprain and strain of lumbar spine	0.004	0.996	0.000
S33.4 Traumatic rupture of symphysis pubis	0.004	0.996	0.000
S33.3 Dislocation of other and unspecified parts of lumbar spine and pelvis	0.004	0.996	0.000
S33.0 Traumatic rupture of lumbar intervertebral disk	0.004	0.996	0.000
S36.9 Injury of unspecified intra-abdominal organ	0.004	0.996	0.000
S36.7 Injury of multiple intra-abdominal organs	0.004	0.996	0.000
S36.6 Injury of rectum	0.004	0.996	0.000
S36.5 Injury of colon	0.004	0.996	0.000
S36.3 Injury of stomach	0.004	0.996	0.000
S36.2 Injury of pancreas	0.004	0.996	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.996	0.004
S36.1 Injury of liver or gallbladder	0.004	0.996	0.000
S33.2 Dislocation of sacro-iliac and sacrococcygeal joint	0.004	0.996	0.000
I61 Intracerebral haemorrhage	0.000	0.996	0.004
C71.0 Cerebrum, except lobes and ventricles	0.004	0.996	0.000
S38.3 Traumatic amputation of other and unspecified parts of abdomen, lower back and pelvis	0.004	0.996	0.000
S38.2 Traumatic amputation of external genital organs	0.004	0.996	0.000
S38.1 Crushing injury of other and unspecified parts of abdomen, lower back and pelvis	0.004	0.996	0.000
S38.0 Crushing injury of external genital organs	0.004	0.996	0.000
G95.1 Vascular myelopathies	0.000	0.996	0.004
S36.4 Injury of small intestine	0.004	0.996	0.000
S36.8 Injury of other intra-abdominal organs	0.004	0.996	0.000
S37.30 Injury of urethra (without open wound into cavity)	0.004	0.996	0.000
M07.3 Other psoriatic arthropathies	0.000	0.996	0.004
S35.9 Injury of unspecified blood vessel at abdomen, lower back and pelvis level	0.004	0.996	0.000
S35.8 Injury of other blood vessels at abdomen, lower back and pelvis level	0.004	0.996	0.000
S35.7 Injury of multiple blood vessels at abdomen, lower back and pelvis level	0.004	0.996	0.000
S35.5 Injury of iliac blood vessels	0.004	0.996	0.000
S35.4 Injury of renal blood vessels	0.004	0.996	0.000
S35.3 Injury of portal or splenic vein	0.004	0.996	0.000
S35.1 Injury of inferior vena cava	0.004	0.996	0.000
S35.0 Injury of abdominal aorta	0.004	0.996	0.000
G96.8 Other specified disorders of central nervous system	0.000	0.996	0.004
L85.3 Xerosis cutis	0.004	0.996	0.000
L85.2 Keratosis punctata (palmaris et plantaris)	0.004	0.996	0.000
L85.0 Acquired ichthyosis	0.004	0.996	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.996	0.004
S36.00 Injury of spleen (without open wound into cavity)	0.004	0.996	0.000
S35.2 Injury of coeliac or mesenteric artery	0.004	0.996	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.996	0.004
S32.2 Fracture of coccyx	0.004	0.996	0.000
I61.8 Other intracerebral haemorrhage	0.000	0.996	0.004
S37.31 Injury of urethra (with open wound into cavity)	0.004	0.996	0.000
G96.9 Disorder of central nervous system, unspecified	0.000	0.996	0.004
C71.6 Cerebellum	0.004	0.996	0.000
S37.20 Injury of bladder (without open wound into cavity)	0.004	0.996	0.000
S32.01 Fracture of lumbar vertebra (open)	0.004	0.996	0.000
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris	0.004	0.996	0.000
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.004	0.996	0.000
S37.00 Injury of kidney (without open wound into cavity)	0.004	0.996	0.000
R45.8 Other symptoms and signs involving emotional state	0.004	0.996	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.996	0.004
S32.3 Fracture of ilium	0.004	0.996	0.000
S37.21 Injury of bladder (with open wound into cavity)	0.003	0.996	0.000
C71.5 Cerebral ventricle	0.004	0.996	0.000
S36.01 Injury of spleen (with open wound into cavity)	0.003	0.996	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.996	0.004
S37.01 Injury of kidney (with open wound into cavity)	0.003	0.996	0.000
H30-H36 Disorders of choroid and retina	0.004	0.996	0.000
S37.11 Injury of ureter (with open wound into cavity)	0.003	0.996	0.000
S37.10 Injury of ureter (without open wound into cavity)	0.003	0.996	0.000
S37.41 Injury of ovary (with open wound into cavity)	0.003	0.996	0.000
S37.40 Injury of ovary (without open wound into cavity)	0.003	0.996	0.000
S37.51 Injury of fallopian tube (with open wound into cavity)	0.003	0.996	0.000
S37.50 Injury of fallopian tube (without open wound into cavity)	0.003	0.996	0.000
S37.61 Injury of uterus (with open wound into cavity)	0.003	0.996	0.000
S37.60 Injury of uterus (without open wound into cavity)	0.003	0.996	0.000
S37.71 Injury of multiple pelvic organs (with open wound into cavity)	0.003	0.996	0.000
S37.70 Injury of multiple pelvic organs (without open wound into cavity)	0.003	0.996	0.000
S37.81 Injury of other pelvic organs (with open wound into cavity)	0.003	0.996	0.000
S37.80 Injury of other pelvic organs (without open wound into cavity)	0.003	0.996	0.000
S37.91 Injury of unspecified pelvic organ (with open wound into cavity)	0.003	0.996	0.000
S37.90 Injury of unspecified pelvic organ (without open wound into cavity)	0.003	0.996	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.003	0.996	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.004	0.996	0.000
C71.7 Brain stem	0.003	0.996	0.000
S32.1 Fracture of sacrum	0.003	0.996	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.003	0.997	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.997	0.003
S36.21 Injury of pancreas (with open wound into cavity)	0.003	0.997	0.000
S36.20 Injury of pancreas (without open wound into cavity)	0.003	0.997	0.000
S36.31 Injury of stomach (with open wound into cavity)	0.003	0.997	0.000
S36.30 Injury of stomach (without open wound into cavity)	0.003	0.997	0.000
S36.51 Injury of colon (with open wound into cavity)	0.003	0.997	0.000
S36.50 Injury of colon (without open wound into cavity)	0.003	0.997	0.000
S36.61 Injury of rectum (with open wound into cavity)	0.003	0.997	0.000
S36.60 Injury of rectum (without open wound into cavity)	0.003	0.997	0.000
S36.71 Injury of multiple intra-abdominal organs (with open wound into cavity)	0.003	0.997	0.000
S36.70 Injury of multiple intra-abdominal organs (without open wound into cavity)	0.003	0.997	0.000
S36.91 Injury of unspecified intra-abdominal organ (with open wound into cavity)	0.003	0.997	0.000
S36.90 Injury of unspecified intra-abdominal organ (without open wound into cavity)	0.003	0.997	0.000
T40.4 Other synthetic narcotics	0.001	0.997	0.003
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.997	0.003
O04.9 Complete or unspecified, without complication	0.000	0.997	0.003
S36.11 Injury of liver or gallbladder (with open wound into cavity)	0.003	0.997	0.000
S36.41 Injury of small intestine (with open wound into cavity)	0.003	0.997	0.000
M07.38 Other psoriatic arthropathies (Other)	0.000	0.997	0.003
G95 Other diseases of spinal cord	0.000	0.997	0.003
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.003	0.997	0.000
S36.81 Injury of other intra-abdominal organs (with open wound into cavity)	0.003	0.997	0.000
C71.3 Parietal lobe	0.003	0.997	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.997	0.003
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.997	0.003
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.997	0.003
C70 Malignant neoplasm of meninges	0.003	0.997	0.000
G95.2 Cord compression, unspecified	0.000	0.997	0.003
S82.21 Fracture of shaft of tibia (open)	0.003	0.997	0.000
E28.2 Polycystic ovarian syndrome	0.003	0.997	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.997	0.003
S36.40 Injury of small intestine (without open wound into cavity)	0.003	0.997	0.000
L05.0 Pilonidal cyst with abscess	0.000	0.997	0.003
C70.0 Cerebral meninges	0.003	0.997	0.000
H31.1 Choroidal degeneration	0.003	0.997	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.003	0.997	0.000
H30 Chorioretinal inflammation	0.003	0.997	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.997	0.003
M19.02 Primary arthrosis of other joints (Upper arm)	0.003	0.997	0.000
S36.80 Injury of other intra-abdominal organs (without open wound into cavity)	0.003	0.997	0.000
S32.21 Fracture of coccyx (open)	0.003	0.997	0.000
S32.20 Fracture of coccyx (closed)	0.003	0.997	0.000
H31 Other disorders of choroid	0.003	0.997	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.997	0.003
E22.1 Hyperprolactinaemia	0.003	0.997	0.000
E24.9 Cushing's syndrome, unspecified	0.003	0.997	0.000
F20.0 Paranoid schizophrenia	0.000	0.997	0.003
C71.8 Overlapping lesion of brain	0.003	0.997	0.000
Z34.8 Supervision of other normal pregnancy	0.003	0.997	0.000
Z36.9 Antenatal screening, unspecified	0.003	0.997	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.003	0.997	0.000
C72.0 Spinal cord	0.003	0.997	0.000
G95.0 Syringomyelia and syringobulbia	0.000	0.997	0.003
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.997	0.003
B18.1 Chronic viral hepatitis B without delta-agent	0.003	0.997	0.000
H34.1 Central retinal artery occlusion	0.003	0.997	0.000
S32.31 Fracture of ilium (open)	0.003	0.997	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.003	0.997	0.000
H30.9 Chorioretinal inflammation, unspecified	0.003	0.997	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.003	0.997	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.003	0.997	0.000
H34 Retinal vascular occlusions	0.003	0.997	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.003	0.997	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.000	0.997	0.003
E27.4 Other and unspecified adrenocortical insufficiency	0.003	0.997	0.000
S32.4 Fracture of acetabulum	0.003	0.997	0.000
E24 Cushing's syndrome	0.003	0.997	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.003	0.997	0.000
S32.11 Fracture of sacrum (open)	0.003	0.997	0.000
E28 Ovarian dysfunction	0.003	0.997	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.997	0.003
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.003	0.997	0.000
T39.1 4-Aminophenol derivatives	0.000	0.997	0.003
S32.30 Fracture of ilium (closed)	0.003	0.997	0.000
H31.3 Choroidal haemorrhage and rupture	0.003	0.997	0.000
C69 Malignant neoplasm of eye and adnexa	0.003	0.997	0.000
G31.2 Degeneration of nervous system due to alcohol	0.003	0.997	0.000
I30.9 Acute pericarditis, unspecified	0.003	0.997	0.000
C70.9 Meninges, unspecified	0.002	0.997	0.000
C70.1 Spinal meninges	0.002	0.997	0.000
F20.5 Residual schizophrenia	0.000	0.997	0.003
M50.0 Cervical disk disorder with myelopathy	0.000	0.997	0.003
E78.4 Other hyperlipidaemia	0.000	0.997	0.003
M19.1 Posttraumatic arthrosis of other joints	0.003	0.997	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.000	0.997	0.003
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.003	0.997	0.000
S32.5 Fracture of pubis	0.002	0.997	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.997	0.003
G95.8 Other specified diseases of spinal cord	0.000	0.997	0.003
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.997	0.002
F20 Schizophrenia	0.000	0.997	0.003
G99.2 Myelopathy in diseases classified elsewhere	0.000	0.997	0.003
C72.9 Central nervous system, unspecified	0.002	0.997	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.002	0.997	0.000
C72.5 Other and unspecified cranial nerves	0.002	0.997	0.000
C72.4 Acoustic nerve	0.002	0.997	0.000
C72.3 Optic nerve	0.002	0.997	0.000
C72.2 Olfactory nerve	0.002	0.997	0.000
C72.1 Cauda equina	0.002	0.997	0.000
H30.8 Other chorioretinal inflammations	0.002	0.997	0.000
H30.1 Disseminated chorioretinal inflammation	0.002	0.997	0.000
H30.0 Focal chorioretinal inflammation	0.002	0.997	0.000
E22 Hyperfunction of pituitary gland	0.003	0.997	0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.003	0.997	0.000
H31.9 Disorder of choroid, unspecified	0.002	0.997	0.000
C69.9 Eye, unspecified	0.002	0.997	0.000
H31.4 Choroidal detachment	0.002	0.997	0.000
H31.2 Hereditary choroidal dystrophy	0.002	0.997	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.002	0.997	0.000
S49.8 Other specified injuries of shoulder and upper arm	0.002	0.998	0.000
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.002	0.998	0.000
H30.2 Posterior cyclitis	0.002	0.998	0.000
G90-G99 Other disorders of the nervous system	0.000	0.998	0.002
E24.8 Other Cushing's syndrome	0.002	0.998	0.000
E20-E35 Disorders of other endocrine glands	0.002	0.998	0.000
C34.1 Upper lobe, bronchus or lung	0.002	0.998	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.002	0.998	0.000
L57.3 Poikiloderma of Civatte	0.002	0.998	0.000
L57.2 Cutis rhomboidalis nuchae	0.002	0.998	0.000
L57.1 Actinic reticuloid	0.002	0.998	0.000
C67.1 Dome of bladder	0.000	0.998	0.002
O70.2 Third degree perineal laceration during delivery	0.002	0.998	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.000	0.998	0.002
K14.8 Other diseases of tongue	0.000	0.998	0.002
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.002	0.998	0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
E24.0 Pituitary-dependent Cushing's disease	0.002	0.998	0.000
H31.8 Other specified disorders of choroid	0.002	0.998	0.000
H34.0 Transient retinal artery occlusion	0.002	0.998	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.000	0.998	0.002
L57.5 Actinic granuloma	0.002	0.998	0.000
M50.2 Other cervical disk displacement	0.000	0.998	0.002
Z31.4 Procreative investigation and testing	0.000	0.998	0.002
C67.5 Bladder neck	0.000	0.998	0.002
E27 Other disorders of adrenal gland	0.002	0.998	0.000
S32.41 Fracture of acetabulum (open)	0.002	0.998	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.002	0.998	0.000
E24.3 Ectopic ACTH syndrome	0.002	0.998	0.000
E24.2 Drug-induced Cushing's syndrome	0.002	0.998	0.000
E24.1 Nelson's syndrome	0.002	0.998	0.000
E34.0 Carcinoid syndrome	0.002	0.998	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
S32.10 Fracture of sacrum (closed)	0.002	0.998	0.000
M19 Other arthrosis	0.002	0.998	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.002	0.998	0.000
E28.9 Ovarian dysfunction, unspecified	0.002	0.998	0.000
E28.8 Other ovarian dysfunction	0.002	0.998	0.000
E28.1 Androgen excess	0.002	0.998	0.000
E28.0 Oestrogen excess	0.002	0.998	0.000
E78.8 Other disorders of lipoprotein metabolism	0.000	0.998	0.002
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.002	0.998	0.000
C69.3 Choroid	0.002	0.998	0.000
G91.1 Obstructive hydrocephalus	0.000	0.998	0.002
S49.9 Unspecified injury of shoulder and upper arm	0.002	0.998	0.000
F20.8 Other schizophrenia	0.000	0.998	0.002
H34.2 Other retinal artery occlusions	0.002	0.998	0.000
E32 Diseases of thymus	0.002	0.998	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.000	0.998	0.002
C69.8 Overlapping lesion of eye and adnexa	0.002	0.998	0.000
C69.5 Lachrymal gland and duct	0.002	0.998	0.000
C69.1 Cornea	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations