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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs368735
log Bayes Factor = 6.01789
Chromosome 6   position 18,293,832  (GRCh37) Explore rs368735 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C43-C44 Melanoma and other malignant neoplasms of skin
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
C44 Other malignant neoplasms of skin
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
I30-I52 Other forms of heart disease
0.997 0.003 0.000
Chapter IX Diseases of the circulatory system
0.994 0.006 0.000
Chapter VIII Diseases of the ear and mastoid process
0.993 0.007 0.000
C44.4 Skin of scalp and neck
0.992 0.008 0.000
M40-M43 Deforming dorsopathies
0.990 0.010 0.000
I42 Cardiomyopathy
0.990 0.010 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.988 0.012 0.000
I51 Complications and ill-defined descriptions of heart disease
0.986 0.014 0.000
I35 Nonrheumatic aortic valve disorders
0.983 0.017 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.982 0.018 0.000
M80-M85 Disorders of bone density and structure
0.979 0.021 0.000
Chapter VII Diseases of the eye and adnexa
0.979 0.021 0.000
C43 Malignant melanoma of skin
0.978 0.022 0.000
M41 Scoliosis
0.974 0.026 0.000
C71 Malignant neoplasm of brain
0.972 0.028 0.000
I35.0 Aortic (valve) stenosis
0.971 0.029 0.000
H65-H75 Diseases of middle ear and mastoid
0.970 0.030 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.961 0.039 0.000
M86-M90 Other osteopathies
0.958 0.042 0.000
M41.9 Scoliosis, unspecified
0.958 0.042 0.000
I51.7 Cardiomegaly
0.951 0.049 0.000
C44.6 Skin of upper limb, including shoulder
0.948 0.052 0.000
M84 Disorders of continuity of bone
0.947 0.053 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.946 0.054 0.000
I42.0 Dilated cardiomyopathy
0.945 0.055 0.000
M20-M25 Other joint disorders
0.937 0.063 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.936 0.064 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.931 0.069 0.000
H55-H59 Other disorders of eye and adnexa
0.925 0.075 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.920 0.080 0.000
I45 Other conduction disorders
0.919 0.081 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.919 0.081 0.000
H72 Perforation of tympanic membrane
0.918 0.082 0.000
H30-H36 Disorders of choroid and retina
0.918 0.082 0.000
I51.8 Other ill-defined heart diseases
0.917 0.083 0.000
I42.9 Cardiomyopathy, unspecified
0.915 0.085 0.000
H66 Suppurative and unspecified otitis media
0.913 0.087 0.000
H60-H62 Diseases of external ear
0.912 0.088 0.000
C71.9 Brain, unspecified
0.912 0.088 0.000
H57 Other disorders of eye and adnexa
0.903 0.097 0.000
M20 Acquired deformities of fingers and toes
0.899 0.101 0.000
I46 Cardiac arrest
0.897 0.103 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.892 0.108 0.000
H35 Other retinal disorders
0.886 0.114 0.000
I60-I69 Cerebrovascular diseases
0.885 0.115 0.000
I51.9 Heart disease, unspecified
0.882 0.118 0.000
C43.9 Malignant melanoma of skin, unspecified
0.882 0.118 0.000
H90-H95 Other disorders of ear
0.882 0.118 0.000
O36 Maternal care for other known or suspected foetal problems
0.878 0.122 0.000
C44.0 Skin of lip
0.878 0.122 0.000
M20.4 Other hammer toe(s) (acquired)
0.873 0.127 0.000
C44.7 Skin of lower limb, including hip
0.866 0.134 0.000
M85 Other disorders of bone density and structure
0.862 0.138 0.000
I45.1 Other and unspecified right bundle-branch block
0.857 0.143 0.000
M43 Other deforming dorsopathies
0.857 0.143 0.000
M45-M49 Spondylopathies
0.856 0.144 0.000
C71.3 Parietal lobe
0.855 0.145 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.855 0.145 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.851 0.149 0.000
M65-M68 Disorders of synovium and tendon
0.849 0.151 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.845 0.154 0.000
I69 Sequelae of cerebrovascular disease
0.846 0.154 0.000
M60-M63 Disorders of muscles
0.845 0.155 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.845 0.155 0.000
C44.3 Skin of other and unspecified parts of face
0.840 0.160 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.840 0.160 0.000
O36.5 Maternal care for poor foetal growth
0.837 0.163 0.000
C69 Malignant neoplasm of eye and adnexa
0.837 0.163 0.000
C51-C58 Malignant neoplasms of female genital organs
0.835 0.165 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.835 0.165 0.000
Q60-Q64 Congenital malformations of the urinary system
0.835 0.165 0.000
H35.9 Retinal disorder, unspecified
0.835 0.165 0.000
H90 Conductive and sensorineural hearing loss
0.834 0.166 0.000
M91-M94 Chondropathies
0.834 0.166 0.000
Chapter XXII Codes for special purposes
0.833 0.167 0.000
H74 Other disorders of middle ear and mastoid
0.831 0.169 0.000
M84.4 Pathological fracture, not elsewhere classified
0.830 0.170 0.000
H57.1 Ocular pain
0.829 0.171 0.000
H61 Other disorders of external ear
0.827 0.173 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.825 0.175 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.825 0.175 0.000
O00-O08 Pregnancy with abortive outcome
0.821 0.179 0.000
H35.6 Retinal haemorrhage
0.820 0.180 0.000
H72.8 Other perforations of tympanic membrane
0.817 0.183 0.000
M87 Osteonecrosis
0.816 0.184 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.816 0.184 0.000
I50 Heart failure
0.816 0.184 0.000
M23 Internal derangement of knee
0.813 0.187 0.000
M89 Other disorders of bone
0.812 0.188 0.000
I63 Cerebral infarction
0.811 0.189 0.000
M20.3 Other deformity of hallux (acquired)
0.808 0.192 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.807 0.193 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.806 0.194 0.000
C44.5 Skin of trunk
0.805 0.195 0.000
M45 Ankylosing spondylitis
0.803 0.197 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.802 0.198 0.000
H66.9 Otitis media, unspecified
0.802 0.198 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.799 0.201 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.798 0.202 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.797 0.203 0.000
C44.1 Skin of eyelid, including canthus
0.796 0.204 0.000
I37 Pulmonary valve disorders
0.796 0.204 0.000
H90.5 Sensorineural hearing loss, unspecified
0.794 0.206 0.000
Q39 Congenital malformations of oesophagus
0.793 0.207 0.000
M84.0 Malunion of fracture
0.792 0.208 0.000
M25 Other joint disorders, not elsewhere classified
0.791 0.209 0.000
C09 Malignant neoplasm of tonsil
0.789 0.211 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.788 0.212 0.000
I46.9 Cardiac arrest, unspecified
0.784 0.216 0.000
M85.0 Fibrous dysplasia (monostotic)
0.783 0.216 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.780 0.220 0.000
C91 Lymphoid leukaemia
0.779 0.221 0.000
M90 Osteopathies in diseases classified elsewhere
0.776 0.224 0.000
H72.0 Central perforation of tympanic membrane
0.775 0.225 0.000
H05 Disorders of orbit
0.775 0.225 0.000
C71.0 Cerebrum, except lobes and ventricles
0.774 0.226 0.000
Q80-Q89 Other congenital malformations
0.772 0.228 0.000
O32.1 Maternal care for breech presentation
0.771 0.229 0.000
M41.8 Other forms of scoliosis
0.770 0.230 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.770 0.230 0.000
I69.3 Sequelae of cerebral infarction
0.770 0.230 0.000
C71.4 Occipital lobe
0.768 0.232 0.000
Q38.7 Pharyngeal pouch
0.767 0.233 0.000
I45.8 Other specified conduction disorders
0.766 0.234 0.000
H61.2 Impacted cerumen
0.766 0.234 0.000
M23.8 Other internal derangements of knee
0.766 0.234 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.765 0.235 0.000
I42.2 Other hypertrophic cardiomyopathy
0.764 0.236 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.761 0.239 0.000
M88 Paget's disease of bone [osteitis deformans]
0.760 0.240 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.760 0.240 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.759 0.241 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.758 0.242 0.000
H47.1 Papilloedema, unspecified
0.757 0.243 0.000
H70 Mastoiditis and related conditions
0.757 0.243 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.755 0.245 0.000
H57.0 Anomalies of pupillary function
0.754 0.246 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.753 0.247 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.752 0.248 0.000
Q43 Other congenital malformations of intestine
0.752 0.248 0.000
M34 Systemic sclerosis
0.751 0.249 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.751 0.249 0.000
I42.8 Other cardiomyopathies
0.751 0.249 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.751 0.249 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.751 0.249 0.000
I45.4 Nonspecific intraventricular block
0.750 0.250 0.000
M40 Kyphosis and lordosis
0.749 0.251 0.000
C44.2 Skin of ear and external auricular canal
0.748 0.252 0.000
C09.9 Tonsil, unspecified
0.748 0.252 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.747 0.253 0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus
0.745 0.255 0.000
H10-H13 Disorders of conjunctiva
0.744 0.256 0.000
M86 Osteomyelitis
0.744 0.256 0.000
M84.8 Other disorders of continuity of bone
0.740 0.260 0.000
I45.9 Conduction disorder, unspecified
0.739 0.261 0.000
C71.8 Overlapping lesion of brain
0.739 0.261 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.738 0.262 0.000
O41 Other disorders of amniotic fluid and membranes
0.736 0.264 0.000
I46.0 Cardiac arrest with successful resuscitation
0.735 0.265 0.000
H60 Otitis externa
0.735 0.265 0.000
M62 Other disorders of muscle
0.734 0.266 0.000
H53-H54 Visual disturbances and blindness
0.733 0.267 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.733 0.267 0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)
0.733 0.267 0.000
O36.8 Maternal care for other specified foetal problems
0.732 0.268 0.000
M21 Other acquired deformities of limbs
0.729 0.271 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.727 0.273 0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)
0.727 0.273 0.000
I36 Nonrheumatic tricuspid valve disorders
0.727 0.273 0.000
H66.3 Other chronic suppurative otitis media
0.726 0.274 0.000
O85-O92 Complications predominantly related to the puerperium
0.725 0.275 0.000
C43.4 Malignant melanoma of scalp and neck
0.724 0.275 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.723 0.277 0.000
C81 Hodgkin's disease
0.722 0.278 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.722 0.278 0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage
0.720 0.279 0.000
Q61 Cystic kidney disease
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C44.8 Overlapping lesion of skin
0.717 0.283 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.716 0.284 0.000
H04 Disorders of lachrymal system
0.715 0.285 0.000
I35.8 Other aortic valve disorders
0.715 0.285 0.000
I52 Other heart disorders in diseases classified elsewhere
0.715 0.285 0.000
I48 Atrial fibrillation and flutter
0.715 0.285 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.715 0.285 0.000
I41 Myocarditis in diseases classified elsewhere
0.715 0.285 0.000
I40 Acute myocarditis
0.715 0.285 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.715 0.285 0.000
I32 Pericarditis in diseases classified elsewhere
0.715 0.285 0.000
M43.0 Spondylolysis
0.713 0.287 0.000
I00-I02 Acute rheumatic fever
0.713 0.287 0.000
M84.48 Pathological fracture, not elsewhere classified (Other)
0.710 0.290 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.710 0.290 0.000
M42 Spinal osteochondrosis
0.710 0.290 0.000
C71.1 Frontal lobe
0.710 0.290 0.000
I42.5 Other restrictive cardiomyopathy
0.709 0.290 0.000
I42.4 Endocardial fibroelastosis
0.709 0.290 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.709 0.290 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.708 0.292 0.000
C70 Malignant neoplasm of meninges
0.708 0.292 0.000
M80 Osteoporosis with pathological fracture
0.707 0.293 0.000
M30 Polyarteritis nodosa and related conditions
0.707 0.293 0.000
I51.5 Myocardial degeneration
0.707 0.293 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.707 0.293 0.000
M46 Other inflammatory spondylopathies
0.706 0.294 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.704 0.296 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.704 0.296 0.000
Q35-Q37 Cleft lip and cleft palate
0.704 0.296 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.704 0.296 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.704 0.296 0.000
M82 Osteoporosis in diseases classified elsewhere
0.704 0.296 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.703 0.297 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.703 0.297 0.000
M83 Adult osteomalacia
0.702 0.298 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.702 0.298 0.000
S40-S49 Injuries to the shoulder and upper arm
0.702 0.298 0.000
I42.6 Alcoholic cardiomyopathy
0.701 0.299 0.000
C43.8 Overlapping malignant melanoma of skin
0.701 0.299 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.701 0.299 0.000
C43.0 Malignant melanoma of lip
0.701 0.299 0.000
U88 Agent resistant to multiple antibiotics
0.699 0.301 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.698 0.301 0.000
I50.0 Congestive heart failure
0.698 0.302 0.000
M41.5 Other secondary scoliosis
0.698 0.302 0.000
M41.4 Neuromuscular scoliosis
0.698 0.302 0.000
M41.3 Thoracogenic scoliosis
0.698 0.302 0.000
M41.2 Other idiopathic scoliosis
0.698 0.302 0.000
M41.1 Juvenile idiopathic scoliosis
0.698 0.302 0.000
M41.0 Infantile idiopathic scoliosis
0.698 0.302 0.000
C71.7 Brain stem
0.697 0.303 0.000
C71.6 Cerebellum
0.697 0.303 0.000
C71.5 Cerebral ventricle
0.697 0.303 0.000
I35.9 Aortic valve disorder, unspecified
0.696 0.304 0.000
M43.1 Spondylolisthesis
0.696 0.304 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.696 0.304 0.000
H68 Eustachian salpingitis and obstruction
0.696 0.304 0.000
H67 Otitis media in diseases classified elsewhere
0.696 0.304 0.000
Q00-Q07 Congenital malformations of the nervous system
0.694 0.306 0.000
I35.1 Aortic (valve) insufficiency
0.693 0.307 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.693 0.307 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.693 0.307 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.692 0.308 0.000
O80-O84 Delivery
0.691 0.309 0.000
H05.8 Other disorders of orbit
0.691 0.309 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.689 0.311 0.000
C95 Leukaemia of unspecified cell type
0.689 0.311 0.000
C94 Other leukaemias of specified cell type
0.689 0.311 0.000
C93 Monocytic leukaemia
0.689 0.311 0.000
C86 Other specified types of T/NK-cell lymphoma
0.689 0.311 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.689 0.311 0.000
H36 Retinal disorders in diseases classified elsewhere
0.688 0.312 0.000
C90.2 Plasmacytoma, extramedullary
0.688 0.312 0.000
M67 Other disorders of synovium and tendon
0.687 0.313 0.000
C71.2 Temporal lobe
0.687 0.313 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.687 0.313 0.000
S42 Fracture of shoulder and upper arm
0.687 0.313 0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.687 0.313 0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.687 0.313 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.687 0.313 0.000
M41.92 Scoliosis, unspecified (Cervical region)
0.687 0.313 0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)
0.687 0.313 0.000
O43 Placental disorders
0.686 0.314 0.000
O45 Premature separation of placenta [abruptio placentae]
0.686 0.314 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.686 0.314 0.000
H47.2 Optic atrophy
0.685 0.315 0.000
M87.9 Osteonecrosis, unspecified
0.685 0.315 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.684 0.316 0.000
Q50-Q56 Congenital malformations of genital organs
0.684 0.316 0.000
I45.2 Bifascicular block
0.684 0.316 0.000
C69.3 Choroid
0.683 0.316 0.000
M25.8 Other specified joint disorders
0.683 0.317 0.000
H35.8 Other specified retinal disorders
0.683 0.317 0.000
M81 Osteoporosis without pathological fracture
0.683 0.317 0.000
M66 Spontaneous rupture of synovium and tendon
0.682 0.318 0.000
O03 Spontaneous abortion
0.682 0.318 0.000
H47.3 Other disorders of optic disk
0.682 0.318 0.000
M33 Dermatopolymyositis
0.680 0.320 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.680 0.320 0.000
M00-M03 Infectious arthropathies
0.680 0.320 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.679 0.321 0.000
O02 Other abnormal products of conception
0.679 0.321 0.000
M84.9 Disorder of continuity of bone, unspecified
0.679 0.321 0.000
M84.3 Stress fracture, not elsewhere classified
0.679 0.321 0.000
M84.2 Delayed union of fracture
0.679 0.321 0.000
H35.4 Peripheral retinal degeneration
0.678 0.322 0.000
H69 Other disorders of Eustachian tube
0.677 0.323 0.000
O40 Polyhydramnios
0.676 0.324 0.000
I61 Intracerebral haemorrhage
0.676 0.324 0.000
C53 Malignant neoplasm of cervix uteri
0.676 0.324 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.675 0.325 0.000
H57.8 Other specified disorders of eye and adnexa
0.674 0.326 0.000
H61.1 Non-infective disorders of pinna
0.673 0.327 0.000
M89.0 Algoneurodystrophy
0.673 0.327 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.672 0.328 0.000
M32 Systemic lupus erythematosus
0.672 0.328 0.000
H90.0 Conductive hearing loss, bilateral
0.669 0.331 0.000
C69.9 Eye, unspecified
0.669 0.331 0.000
Q45 Other congenital malformations of digestive system
0.668 0.332 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.668 0.332 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.668 0.332 0.000
Q40 Other congenital malformations of upper alimentary tract
0.668 0.332 0.000
M89.9 Disorder of bone, unspecified
0.668 0.332 0.000
I51.0 Cardiac septal defect, acquired
0.667 0.332 0.000
C92 Myeloid leukaemia
0.667 0.333 0.000
M93 Other osteochondropathies
0.667 0.333 0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)
0.667 0.333 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.667 0.333 0.000
I38 Endocarditis, valve unspecified
0.665 0.335 0.000
H04.2 Epiphora
0.665 0.335 0.000
H72.2 Other marginal perforations of tympanic membrane
0.664 0.335 0.000
H33 Retinal detachments and breaks
0.665 0.335 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.664 0.336 0.000
H01 Other inflammation of eyelid
0.662 0.338 0.000
C54 Malignant neoplasm of corpus uteri
0.662 0.338 0.000
H00 Hordeolum and chalazion
0.661 0.339 0.000
C73 Malignant neoplasm of thyroid gland
0.660 0.339 0.000
M20.2 Hallux rigidus
0.660 0.340 0.000
O33 Maternal care for known or suspected disproportion
0.660 0.340 0.000
O31 Complications specific to multiple gestation
0.660 0.340 0.000
M25.9 Joint disorder, unspecified
0.659 0.341 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.659 0.341 0.000
I45.0 Right fascicular block
0.659 0.341 0.000
H35.2 Other proliferative retinopathy
0.659 0.341 0.000
I33 Acute and subacute endocarditis
0.658 0.342 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.658 0.342 0.000
H72.1 Attic perforation of tympanic membrane
0.658 0.342 0.000
D00-D09 In situ neoplasms
0.658 0.342 0.000
O36.4 Maternal care for intra-uterine death
0.658 0.342 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.658 0.342 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.658 0.342 0.000
H30 Chorioretinal inflammation
0.658 0.342 0.000
H74.0 Tympanosclerosis
0.658 0.342 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.657 0.343 0.000
Q85 Phakomatoses, not elsewhere classified
0.655 0.345 0.000
H66.4 Suppurative otitis media, unspecified
0.655 0.345 0.000
H66.0 Acute suppurative otitis media
0.655 0.345 0.000
M62.8 Other specified disorders of muscle
0.655 0.345 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.654 0.346 0.000
O32.0 Maternal care for unstable lie
0.654 0.346 0.000
H05.2 Exophthalmic conditions
0.653 0.347 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.653 0.347 0.000
O47 False labour
0.652 0.348 0.000
S42.2 Fracture of upper end of humerus
0.652 0.348 0.000
I37.1 Pulmonary valve insufficiency
0.651 0.348 0.000
M87.8 Other osteonecrosis
0.651 0.349 0.000
I30 Acute pericarditis
0.651 0.349 0.000
S42.0 Fracture of clavicle
0.650 0.350 0.000
Q39.6 Diverticulum of oesophagus
0.649 0.351 0.000
M90.7 Fracture of bone in neoplastic disease
0.646 0.354 0.000
M84.07 Malunion of fracture (Ankle and foot)
0.644 0.355 0.000
H47.0 Disorders of optic nerve, not elsewhere classified
0.644 0.355 0.000
O32.8 Maternal care for other malpresentation of foetus
0.644 0.355 0.000
M23.5 Chronic instability of knee
0.644 0.356 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.643 0.357 0.000
I46.1 Sudden cardiac death, so described
0.643 0.357 0.000
O32.3 Maternal care for face, brow and chin presentation
0.642 0.358 0.000
H31 Other disorders of choroid
0.641 0.359 0.000
H90.3 Sensorineural hearing loss, bilateral
0.641 0.359 0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified
0.641 0.359 0.000
Q63 Other congenital malformations of kidney
0.640 0.359 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.639 0.360 0.000
Q39.4 Oesophageal web
0.638 0.362 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.637 0.362 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.637 0.363 0.000
C91.1 Chronic lymphocytic leukaemia
0.636 0.364 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.636 0.364 0.000
H35.1 Retinopathy of prematurity
0.635 0.365 0.000
O04 Medical abortion
0.635 0.365 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.635 0.365 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.635 0.365 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.635 0.365 0.000
M85.6 Other cyst of bone
0.635 0.365 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.633 0.367 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.632 0.368 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.632 0.368 0.000
I62 Other nontraumatic intracranial haemorrhage
0.631 0.369 0.000
C88 Malignant immunoproliferative diseases
0.630 0.370 0.000
M23.0 Cystic meniscus
0.630 0.370 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.630 0.370 0.000
O36.2 Maternal care for hydrops foetalis
0.630 0.370 0.000
O36.1 Maternal care for other isoimmunisation
0.630 0.370 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.629 0.371 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.629 0.371 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.629 0.371 0.000
I05-I09 Chronic rheumatic heart diseases
0.629 0.371 0.000
M49 Spondylopathies in diseases classified elsewhere
0.628 0.372 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.627 0.372 0.000
C12 Malignant neoplasm of pyriform sinus
0.627 0.373 0.000
S42.20 Fracture of upper end of humerus (closed)
0.627 0.373 0.000
C90.0 Multiple myeloma
0.627 0.373 0.000
C64-C68 Malignant neoplasms of urinary tract
0.627 0.373 0.000
M94 Other disorders of cartilage
0.626 0.374 0.000
M88.8 Paget's disease of other bones
0.625 0.375 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.625 0.375 0.000
M41.86 Other forms of scoliosis (Lumbar region)
0.624 0.376 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.624 0.376 0.000
M84.04 Malunion of fracture (Hand)
0.624 0.376 0.000
S42.00 Fracture of clavicle (closed)
0.623 0.377 0.000
I50.9 Heart failure, unspecified
0.623 0.377 0.000
O03.4 Incomplete, without complication
0.623 0.377 0.000
Q43.8 Other specified congenital malformations of intestine
0.623 0.377 0.000
C83.3 Large cell (diffuse)
0.623 0.377 0.000
O34.1 Maternal care for tumour of corpus uteri
0.623 0.377 0.000
H33.2 Serous retinal detachment
0.622 0.378 0.000
M65 Synovitis and tenosynovitis
0.620 0.380 0.000
H10 Conjunctivitis
0.620 0.380 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.620 0.380 0.000
C05 Malignant neoplasm of palate
0.619 0.381 0.000
M85.9 Disorder of bone density and structure, unspecified
0.618 0.382 0.000
M85.5 Aneurysmal bone cyst
0.618 0.382 0.000
M85.4 Solitary bone cyst
0.618 0.382 0.000
M85.3 Osteitis condensans
0.618 0.382 0.000
M85.2 Hyperostosis of skull
0.618 0.382 0.000
M85.1 Skeletal fluorosis
0.618 0.382 0.000
S40 Superficial injury of shoulder and upper arm
0.615 0.385 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.614 0.385 0.000
M43.9 Deforming dorsopathy, unspecified
0.614 0.386 0.000
M43.8 Other specified deforming dorsopathies
0.614 0.386 0.000
M43.6 Torticollis
0.614 0.386 0.000
M43.5 Other recurrent vertebral subluxation
0.614 0.386 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.614 0.386 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.614 0.386 0.000
M43.2 Other fusion of spine
0.614 0.386 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.614 0.386 0.000
C84.5 Other and unspecified T-cell lymphomas
0.614 0.386 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.613 0.387 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.613 0.387 0.000
H35.7 Separation of retinal layers
0.612 0.387 0.000
O41.8 Other specified disorders of amniotic fluid and membranes
0.612 0.388 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.610 0.390 0.000
H54 Blindness and low vision
0.610 0.390 0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures
0.610 0.390 0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation
0.610 0.390 0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs
0.610 0.390 0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol
0.610 0.390 0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother
0.610 0.390 0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus
0.610 0.390 0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus
0.610 0.390 0.000
M92 Other juvenile osteochondrosis
0.609 0.390 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.609 0.391 0.000
C45 Mesothelioma
0.609 0.391 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.608 0.392 0.000
Q66 Congenital deformities of feet
0.607 0.393 0.000
C15-C26 Malignant neoplasms of digestive organs
0.607 0.393 0.000
O44 Placenta praevia
0.606 0.394 0.000
C13 Malignant neoplasm of hypopharynx
0.606 0.394 0.000
C11 Malignant neoplasm of nasopharynx
0.606 0.394 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.606 0.394 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.606 0.394 0.000
C03 Malignant neoplasm of gum
0.606 0.394 0.000
C00 Malignant neoplasm of lip
0.606 0.394 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.606 0.394 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.606 0.394 0.000
M61 Calcification and ossification of muscle
0.606 0.394 0.000
M60 Myositis
0.606 0.394 0.000
H47.7 Disorder of visual pathways, unspecified
0.606 0.394 0.000
H47.6 Disorders of visual cortex
0.606 0.394 0.000
H47.5 Disorders of other visual pathways
0.606 0.394 0.000
H47.4 Disorders of optic chiasm
0.606 0.394 0.000
M23.3 Other meniscus derangements
0.606 0.394 0.000
H70.9 Mastoiditis, unspecified
0.603 0.396 0.000
H60.1 Cellulitis of external ear
0.603 0.397 0.000
I45.3 Trifascicular block
0.603 0.397 0.000
I10-I15 Hypertensive diseases
0.603 0.397 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.602 0.398 0.000
O32.6 Maternal care for compound presentation
0.602 0.398 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.602 0.398 0.000
H04.8 Other disorders of lachrymal system
0.602 0.398 0.000
M23.4 Loose body in knee
0.601 0.398 0.000
Q76 Congenital malformations of spine and bony thorax
0.601 0.399 0.000
C69.8 Overlapping lesion of eye and adnexa
0.600 0.400 0.000
C69.6 Orbit
0.600 0.400 0.000
C69.5 Lachrymal gland and duct
0.600 0.400 0.000
C69.4 Ciliary body
0.600 0.400 0.000
C69.2 Retina
0.600 0.400 0.000
C69.1 Cornea
0.600 0.400 0.000
C69.0 Conjunctiva
0.600 0.400 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.599 0.401 0.000
C58 Malignant neoplasm of placenta
0.599 0.401 0.000
C52 Malignant neoplasm of vagina
0.599 0.401 0.000
Q38.8 Other congenital malformations of pharynx
0.599 0.401 0.000
Q38.6 Other congenital malformations of mouth
0.599 0.401 0.000
Q38.5 Congenital malformations of palate, not elsewhere classified
0.599 0.401 0.000
Q38.4 Congenital malformations of salivary glands and ducts
0.599 0.401 0.000
Q38.3 Other congenital malformations of tongue
0.599 0.401 0.000
Q38.2 Macroglossia
0.599 0.401 0.000
Q38.1 Ankyloglossia
0.599 0.401 0.000
Q38.0 Congenital malformations of lips, not elsewhere classified
0.599 0.401 0.000
Q64 Other congenital malformations of urinary system
0.599 0.401 0.000
H73 Other disorders of tympanic membrane
0.599 0.401 0.000
S20-S29 Injuries to the thorax
0.598 0.402 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.598 0.402 0.000
H91 Other hearing loss
0.598 0.402 0.000
O36.6 Maternal care for excessive foetal growth
0.597 0.403 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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