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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3735533
log Bayes Factor = 9.47729
Chromosome 7   position 27,245,893  (GRCh37) Explore rs3735533 on Ensembl!
Variant rs3735533 is part of Cluster X0011

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I10 Essential (primary) hypertension
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.508 0.492
I51.9 Heart disease, unspecified
0.000 0.600 0.400
I51 Complications and ill-defined descriptions of heart disease
0.000 0.603 0.397
I30-I52 Other forms of heart disease
0.000 0.615 0.385
I44 Atrioventricular and left bundle-branch block
0.000 0.620 0.380
I50 Heart failure
0.000 0.621 0.379
I44.0 Atrioventricular block, first degree
0.000 0.622 0.378
I51.8 Other ill-defined heart diseases
0.000 0.628 0.372
I50.1 Left ventricular failure
0.000 0.642 0.358
I13 Hypertensive heart and renal disease
0.000 0.647 0.353
I50.9 Heart failure, unspecified
0.000 0.650 0.350
I45 Other conduction disorders
0.000 0.659 0.341
Chapter IX Diseases of the circulatory system
0.000 0.670 0.330
I44.3 Other and unspecified atrioventricular block
0.000 0.682 0.318
I35 Nonrheumatic aortic valve disorders
0.000 0.682 0.318
I11 Hypertensive heart disease
0.000 0.687 0.313
I12 Hypertensive renal disease
0.000 0.691 0.309
I51.7 Cardiomegaly
0.000 0.693 0.307
I51.4 Myocarditis, unspecified
0.000 0.694 0.306
I15 Secondary hypertension
0.000 0.694 0.305
I35.0 Aortic (valve) stenosis
0.000 0.697 0.303
I44.7 Left bundle-branch block, unspecified
0.000 0.703 0.297
I37 Pulmonary valve disorders
0.000 0.707 0.292
I36 Nonrheumatic tricuspid valve disorders
0.000 0.708 0.292
I50.0 Congestive heart failure
0.000 0.708 0.292
I44.6 Other and unspecified fascicular block
0.000 0.712 0.288
I51.5 Myocardial degeneration
0.000 0.715 0.285
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.715 0.285
I51.6 Cardiovascular disease, unspecified
0.000 0.715 0.284
I05-I09 Chronic rheumatic heart diseases
0.000 0.716 0.284
I45.1 Other and unspecified right bundle-branch block
0.000 0.716 0.284
I30 Acute pericarditis
0.000 0.716 0.284
I52 Other heart disorders in diseases classified elsewhere
0.000 0.724 0.276
I48 Atrial fibrillation and flutter
0.000 0.724 0.276
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.724 0.276
I41 Myocarditis in diseases classified elsewhere
0.000 0.724 0.276
I40 Acute myocarditis
0.000 0.724 0.276
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.724 0.276
I32 Pericarditis in diseases classified elsewhere
0.000 0.724 0.276
I44.5 Left posterior fascicular block
0.000 0.728 0.272
I44.4 Left anterior fascicular block
0.000 0.728 0.272
I33 Acute and subacute endocarditis
0.000 0.728 0.272
I45.2 Bifascicular block
0.000 0.729 0.271
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.731 0.269
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.731 0.269
I08 Multiple valve diseases
0.000 0.732 0.268
I45.3 Trifascicular block
0.000 0.732 0.268
I45.9 Conduction disorder, unspecified
0.000 0.733 0.267
I45.5 Other specified heart block
0.000 0.737 0.263
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.742 0.258
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.747 0.253
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.747 0.253
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.747 0.253
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.747 0.253
I45.4 Nonspecific intraventricular block
0.000 0.755 0.245
I45.8 Other specified conduction disorders
0.000 0.755 0.245
I45.0 Right fascicular block
0.000 0.755 0.245
I51.0 Cardiac septal defect, acquired
0.000 0.755 0.245
I00-I02 Acute rheumatic fever
0.000 0.763 0.237
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.768 0.232
I37.1 Pulmonary valve insufficiency
0.000 0.774 0.226
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.774 0.225
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.775 0.224
I12.9 Hypertensive renal disease without renal failure
0.000 0.778 0.222
I15.8 Other secondary hypertension
0.000 0.781 0.219
I15.2 Hypertension secondary to endocrine disorders
0.000 0.781 0.219
I15.0 Renovascular hypertension
0.000 0.781 0.219
I15.1 Hypertension secondary to other renal disorders
0.000 0.783 0.217
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.784 0.216
I44.2 Atrioventricular block, complete
0.000 0.784 0.215
I30.9 Acute pericarditis, unspecified
0.000 0.788 0.212
I37.9 Pulmonary valve disorder, unspecified
0.000 0.790 0.210
I37.8 Other pulmonary valve disorders
0.000 0.790 0.210
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.790 0.210
I37.0 Pulmonary valve stenosis
0.000 0.790 0.210
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.790 0.209
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.790 0.209
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.790 0.209
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.790 0.209
I35.8 Other aortic valve disorders
0.000 0.791 0.209
I35.1 Aortic (valve) insufficiency
0.000 0.795 0.205
I09 Other rheumatic heart diseases
0.000 0.796 0.204
I06 Rheumatic aortic valve diseases
0.000 0.796 0.204
I30.8 Other forms of acute pericarditis
0.000 0.796 0.204
I30.1 Infective pericarditis
0.000 0.796 0.204
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.796 0.204
I35.9 Aortic valve disorder, unspecified
0.000 0.797 0.203
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.799 0.201
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.802 0.198
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.802 0.198
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.802 0.198
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.802 0.198
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.802 0.198
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.802 0.198
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.802 0.198
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.802 0.198
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.802 0.198
I40.9 Acute myocarditis, unspecified
0.000 0.802 0.198
I40.8 Other acute myocarditis
0.000 0.802 0.198
I40.1 Isolated myocarditis
0.000 0.802 0.198
I40.0 Infective myocarditis
0.000 0.802 0.198
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.802 0.198
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.802 0.198
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.802 0.198
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.802 0.198
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.802 0.198
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.802 0.198
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.802 0.198
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.802 0.198
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.802 0.198
I48.4 Atypical atrial flutter
0.000 0.802 0.198
I48.3 Typical atrial flutter
0.000 0.802 0.198
I48.2 Chronic atrial fibrillation
0.000 0.802 0.198
I48.1 Persistent atrial fibrillation
0.000 0.802 0.198
I48.0 Paroxysmal atrial fibrillation
0.000 0.802 0.198
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.802 0.198
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.802 0.198
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.802 0.198
I33.9 Acute endocarditis, unspecified
0.000 0.805 0.195
I08.9 Multiple valve disease, unspecified
0.000 0.807 0.193
I47 Paroxysmal tachycardia
0.000 0.808 0.192
I33.0 Acute and subacute infective endocarditis
0.000 0.809 0.191
I99 Other and unspecified disorders of circulatory system
0.000 0.810 0.190
I45.6 Preexcitation syndrome
0.000 0.811 0.189
I44.1 Atrioventricular block, second degree
0.000 0.811 0.189
I05 Rheumatic mitral valve diseases
0.000 0.813 0.187
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.815 0.184
I08.8 Other multiple valve diseases
0.000 0.817 0.183
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.818 0.182
I12.0 Hypertensive renal disease with renal failure
0.000 0.822 0.178
I42 Cardiomyopathy
0.000 0.824 0.176
I15.9 Seconday hypertension, unspecified
0.001 0.825 0.175
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.828 0.172
I02 Rheumatic chorea
0.000 0.830 0.170
I01 Rheumatic fever with heart involvement
0.000 0.830 0.170
I00 Rheumatic fever without mention of heart involvement
0.000 0.830 0.170
I08.0 Disorders of both mitral and aortic valves
0.000 0.841 0.159
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.841 0.158
I38 Endocarditis, valve unspecified
0.000 0.847 0.153
I07 Rheumatic tricuspid valve diseases
0.000 0.849 0.151
I34 Nonrheumatic mitral valve disorders
0.000 0.853 0.147
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.853 0.147
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.853 0.146
I06.8 Other rheumatic aortic valve diseases
0.000 0.853 0.146
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.853 0.146
I06.1 Rheumatic aortic insufficiency
0.000 0.853 0.146
I06.0 Rheumatic aortic stenosis
0.000 0.853 0.146
I09.9 Rheumatic heart disease, unspecified
0.000 0.853 0.146
I09.8 Other specified rheumatic heart diseases
0.000 0.853 0.146
I09.2 Chronic rheumatic pericarditis
0.000 0.853 0.146
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.853 0.146
I09.0 Rheumatic myocarditis
0.000 0.853 0.146
I47.2 Ventricular tachycardia
0.000 0.855 0.145
I05.1 Rheumatic mitral insufficiency
0.000 0.857 0.143
I05.2 Mitral stenosis with insufficiency
0.000 0.860 0.140
I47.0 Reentry ventricular arrhythmia
0.000 0.862 0.138
I46 Cardiac arrest
0.000 0.865 0.135
I42.0 Dilated cardiomyopathy
0.000 0.866 0.134
I05.8 Other mitral valve diseases
0.000 0.866 0.134
I05.0 Mitral stenosis
0.000 0.868 0.132
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.868 0.132
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.869 0.131
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.869 0.131
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.869 0.131
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.869 0.131
I98.0 Cardiovascular syphilis
0.000 0.869 0.131
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.874 0.126
I42.5 Other restrictive cardiomyopathy
0.000 0.874 0.126
I42.4 Endocardial fibroelastosis
0.000 0.874 0.126
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.874 0.126
I42.6 Alcoholic cardiomyopathy
0.000 0.874 0.126
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.878 0.122
I01.8 Other acute rheumatic heart disease
0.000 0.878 0.122
I01.2 Acute rheumatic myocarditis
0.000 0.878 0.122
I01.1 Acute rheumatic endocarditis
0.000 0.878 0.122
I01.0 Acute rheumatic pericarditis
0.000 0.878 0.122
I02.9 Rheumatic chorea without heart involvement
0.000 0.878 0.122
I02.0 Rheumatic chorea with heart involvement
0.000 0.878 0.122
I42.2 Other hypertrophic cardiomyopathy
0.000 0.882 0.118
I31 Other diseases of pericardium
0.001 0.886 0.114
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.886 0.114
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.886 0.114
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.886 0.114
I97.0 Postcardiotomy syndrome
0.000 0.886 0.114
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.890 0.110
I07.9 Tricuspid valve disease, unspecified
0.000 0.891 0.108
I07.8 Other tricuspid valve diseases
0.000 0.891 0.108
I07.2 Tricuspid stenosis with insufficiency
0.000 0.891 0.108
I07.0 Tricuspid stenosis
0.000 0.891 0.108
I42.9 Cardiomyopathy, unspecified
0.000 0.893 0.107
I95 Hypotension
0.000 0.893 0.107
I97.1 Other functional disturbances following cardiac surgery
0.000 0.894 0.105
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.894 0.105
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.894 0.105
I46.1 Sudden cardiac death, so described
0.000 0.903 0.097
I05.9 Mitral valve disease, unspecified
0.000 0.905 0.095
I28 Other diseases of pulmonary vessels
0.000 0.905 0.094
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.905 0.094
I42.8 Other cardiomyopathies
0.000 0.908 0.092
I49 Other cardiac arrhythmias
0.000 0.911 0.089
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.083 0.917 0.000
I31.8 Other specified diseases of pericardium
0.001 0.918 0.082
I31.2 Haemopericardium, not elsewhere classified
0.001 0.918 0.082
I31.1 Chronic constrictive pericarditis
0.001 0.918 0.082
I31.0 Chronic adhesive pericarditis
0.001 0.918 0.082
I34.1 Mitral (valve) prolapse
0.000 0.919 0.081
I95.2 Hypotension due to drugs
0.000 0.919 0.081
I95.8 Other hypotension
0.000 0.923 0.077
I49.9 Cardiac arrhythmia, unspecified
0.000 0.926 0.074
M06.9 Rheumatoid arthritis, unspecified
0.073 0.927 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.071 0.929 0.000
I95.0 Idiopathic hypotension
0.000 0.931 0.069
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.932 0.068
I28.8 Other specified diseases of pulmonary vessels
0.000 0.932 0.068
I28.1 Aneurysm of pulmonary artery
0.000 0.932 0.068
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.932 0.068
I27 Other pulmonary heart diseases
0.000 0.934 0.066
I49.2 Junctional premature depolarisation
0.000 0.936 0.064
I95.9 Hypotension, unspecified
0.000 0.937 0.063
I34.0 Mitral (valve) insufficiency
0.000 0.937 0.063
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.062 0.938 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.061 0.939 0.000
I46.9 Cardiac arrest, unspecified
0.000 0.939 0.061
I49.5 Sick sinus syndrome
0.000 0.939 0.060
I49.1 Atrial premature depolarisation
0.000 0.943 0.056
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.056 0.944 0.000
I07.1 Tricuspid insufficiency
0.001 0.944 0.055
I49.0 Ventricular fibrillation and flutter
0.000 0.947 0.053
M06.98 Rheumatoid arthritis, unspecified (Other)
0.053 0.947 0.000
I26 Pulmonary embolism
0.001 0.949 0.051
I95.1 Orthostatic hypotension
0.000 0.950 0.050
I47.1 Supraventricular tachycardia
0.000 0.950 0.050
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.049 0.951 0.000
I27.9 Pulmonary heart disease, unspecified
0.000 0.951 0.048
I49.4 Other and unspecified premature depolarisation
0.000 0.952 0.048
F32 Depressive episode
0.048 0.952 0.000
I27.8 Other specified pulmonary heart diseases
0.000 0.952 0.047
I27.1 Kyphoscoliotic heart disease
0.000 0.952 0.047
I49.3 Ventricular premature depolarisation
0.000 0.953 0.047
F30-F39 Mood [affective] disorders
0.046 0.954 0.000
F33 Recurrent depressive disorder
0.046 0.954 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.046 0.954 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.046 0.954 0.000
M47.82 Other spondylosis (Cervical region)
0.045 0.955 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.045 0.955 0.000
F33.9 Recurrent depressive disorder, unspecified
0.044 0.956 0.000
I46.0 Cardiac arrest with successful resuscitation
0.000 0.957 0.043
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.043 0.957 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.042 0.957 0.000
F31 Bipolar affective disorder
0.042 0.958 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.042 0.958 0.000
I27.0 Primary pulmonary hypertension
0.000 0.958 0.041
I31.3 Pericardial effusion (noninflammatory)
0.001 0.959 0.040
F32.9 Depressive episode, unspecified
0.038 0.962 0.000
F32.0 Mild depressive episode
0.037 0.963 0.000
M06 Other rheumatoid arthritis
0.037 0.963 0.000
F32.8 Other depressive episodes
0.036 0.964 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.035 0.965 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.001 0.965 0.034
F31.9 Bipolar affective disorder, unspecified
0.034 0.966 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.033 0.967 0.000
F38 Other mood [affective] disorders
0.033 0.967 0.000
F34 Persistent mood [affective] disorders
0.033 0.967 0.000
F33.8 Other recurrent depressive disorders
0.033 0.967 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.033 0.967 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.033 0.967 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.033 0.967 0.000
F39 Unspecified mood [affective] disorder
0.033 0.967 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.032 0.968 0.000
F30 Manic episode
0.032 0.968 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.032 0.968 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.032 0.968 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.031 0.969 0.000
F31.8 Other bipolar affective disorders
0.030 0.970 0.000
F31.7 Bipolar affective disorder, currently in remission
0.030 0.970 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.030 0.970 0.000
I31.9 Disease of pericardium, unspecified
0.001 0.970 0.029
I49.8 Other specified cardiac arrhythmias
0.000 0.970 0.029
F32.1 Moderate depressive episode
0.030 0.970 0.000
M47.8 Other spondylosis
0.029 0.971 0.000
M06.3 Rheumatoid nodule
0.029 0.971 0.000
I27.2 Other secondary pulmonary hypertension
0.000 0.972 0.027
M06.4 Inflammatory polyarthropathy
0.027 0.973 0.000
M06.8 Other specified rheumatoid arthritis
0.026 0.973 0.000
M06.2 Rheumatoid bursitis
0.026 0.973 0.000
M06.1 Adult-onset Still's disease
0.026 0.973 0.000
F30.9 Manic episode, unspecified
0.025 0.975 0.000
M06.0 Seronegative rheumatoid arthritis
0.024 0.975 0.000
M47.89 Other spondylosis (Site unspecified)
0.024 0.976 0.000
F34.9 Persistent mood [affective] disorder, unspecified
0.024 0.976 0.000
F34.8 Other persistent mood [affective] disorders
0.024 0.976 0.000
F34.1 Dysthymia
0.024 0.976 0.000
F34.0 Cyclothymia
0.024 0.976 0.000
F38.8 Other specified mood [affective] disorders
0.024 0.976 0.000
F38.1 Other recurrent mood [affective] disorders
0.024 0.976 0.000
F38.0 Other single mood [affective] disorders
0.024 0.976 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.024 0.976 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.023 0.976 0.000
F30.8 Other manic episodes
0.023 0.977 0.000
F30.2 Mania with psychotic symptoms
0.023 0.977 0.000
F30.1 Mania without psychotic symptoms
0.023 0.977 0.000
I60-I69 Cerebrovascular diseases
0.000 0.977 0.023
M06.32 Rheumatoid nodule (Upper arm)
0.023 0.977 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.022 0.978 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.021 0.979 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.021 0.979 0.000
M47.84 Other spondylosis (Thoracic region)
0.021 0.979 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.021 0.979 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.021 0.979 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.021 0.979 0.000
M06.38 Rheumatoid nodule (Other)
0.021 0.979 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.021 0.979 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.021 0.979 0.000
M06.33 Rheumatoid nodule (Forearm)
0.021 0.979 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.021 0.979 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.021 0.979 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.020 0.980 0.000
F30.0 Hypomania
0.020 0.980 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.019 0.980 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.019 0.980 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.019 0.980 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.019 0.980 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.019 0.980 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.019 0.980 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.019 0.980 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.019 0.980 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.019 0.980 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.019 0.981 0.000
M06.34 Rheumatoid nodule (Hand)
0.019 0.981 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.019 0.981 0.000
M06.18 Adult-onset Still's disease (Other)
0.019 0.981 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.019 0.981 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.019 0.981 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.019 0.981 0.000
M06.14 Adult-onset Still's disease (Hand)
0.019 0.981 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.019 0.981 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.019 0.981 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.019 0.981 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.019 0.981 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.019 0.981 0.000
M06.28 Rheumatoid bursitis (Other)
0.019 0.981 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.019 0.981 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.019 0.981 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.019 0.981 0.000
M06.24 Rheumatoid bursitis (Hand)
0.019 0.981 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.019 0.981 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.019 0.981 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.019 0.981 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.019 0.981 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.019 0.981 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.019 0.981 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.019 0.981 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.019 0.981 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.019 0.981 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.019 0.981 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.019 0.981 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.019 0.981 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.019 0.981 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.019 0.981 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.018 0.982 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.018 0.982 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.018 0.982 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.018 0.982 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.018 0.982 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.018 0.982 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.018 0.982 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.018 0.982 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.018 0.982 0.000
I62 Other nontraumatic intracranial haemorrhage
0.000 0.983 0.017
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.983 0.017
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.983 0.017
I60 Subarachnoid haemorrhage
0.000 0.984 0.016
M47 Spondylosis
0.016 0.984 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.016 0.984 0.000
I61 Intracerebral haemorrhage
0.000 0.985 0.015
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.985 0.015
R32 Unspecified urinary incontinence
0.014 0.986 0.000
R35 Polyuria
0.014 0.986 0.000
I20-I25 Ischaemic heart diseases
0.000 0.986 0.014
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.986 0.014
M45-M49 Spondylopathies
0.013 0.987 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.987 0.013
I62.1 Nontraumatic extradural haemorrhage
0.000 0.987 0.012
I69 Sequelae of cerebrovascular disease
0.000 0.987 0.013
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.987 0.012
M47.2 Other spondylosis with radiculopathy
0.012 0.988 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.988 0.012
I60.8 Other subarachnoid haemorrhage
0.000 0.988 0.012
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.988 0.012
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.988 0.012
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.988 0.012
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.988 0.012
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.988 0.012
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.988 0.012
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.988 0.012
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.988 0.012
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.988 0.012
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.988 0.012
I68.0 Cerebral amyloid angiopathy
0.000 0.988 0.012
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.988 0.012
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.988 0.012
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.988 0.012
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.988 0.012
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.988 0.012
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.988 0.012
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.988 0.012
M47.0 Anterior spinal and vertebral artery compression syndromes
0.012 0.988 0.000
M45 Ankylosing spondylitis
0.011 0.989 0.000
M48 Other spondylopathies
0.011 0.989 0.000
M46 Other inflammatory spondylopathies
0.011 0.989 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.989 0.011
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.989 0.011
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.989 0.011
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.989 0.011
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.011 0.989 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.011 0.989 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.990 0.010
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.990 0.010
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.990 0.010
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.990 0.010
M47.1 Other spondylosis with myelopathy
0.010 0.990 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.010 0.990 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.990 0.010
I23 Certain current complications following acute myocardial infarction
0.000 0.990 0.010
I61.8 Other intracerebral haemorrhage
0.000 0.990 0.010
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.990 0.010
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.990 0.010
I70 Atherosclerosis
0.000 0.990 0.010
M49 Spondylopathies in diseases classified elsewhere
0.010 0.990 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.009 0.990 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.009 0.990 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.009 0.990 0.000
I67 Other cerebrovascular diseases
0.000 0.991 0.009
I24 Other acute ischaemic heart diseases
0.000 0.991 0.009
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)
0.009 0.991 0.000
E11.3 With ophthalmic complications
0.009 0.991 0.000
I78 Diseases of capillaries
0.000 0.991 0.009
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.991 0.009
I74 Arterial embolism and thrombosis
0.000 0.991 0.009
M47.29 Other spondylosis with radiculopathy (Site unspecified)
0.009 0.991 0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)
0.009 0.991 0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)
0.009 0.991 0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)
0.009 0.991 0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)
0.009 0.991 0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)
0.009 0.991 0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)
0.009 0.991 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.991 0.009
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.991 0.009
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.991 0.009
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.991 0.009
I65.1 Occlusion and stenosis of basilar artery
0.000 0.991 0.009
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.991 0.009
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.009 0.991 0.000
M47.86 Other spondylosis (Lumbar region)
0.009 0.991 0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)
0.009 0.991 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.009 0.991 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.991 0.009
M47.09 Anterior spinal and vertebral artery compression syndromes (Site unspecified)
0.008 0.991 0.000
M47.08 Anterior spinal and vertebral artery compression syndromes (Sacral and sacrococcygeal region)
0.008 0.991 0.000
M47.07 Anterior spinal and vertebral artery compression syndromes (Lumbosacral region)
0.008 0.991 0.000
M47.06 Anterior spinal and vertebral artery compression syndromes (Lumbar region)
0.008 0.991 0.000
M47.05 Anterior spinal and vertebral artery compression syndromes (Thoracolumbar region)
0.008 0.991 0.000
M47.04 Anterior spinal and vertebral artery compression syndromes (Thoracic region)
0.008 0.991 0.000
M47.03 Anterior spinal and vertebral artery compression syndromes (Cervicothoracic region)
0.008 0.991 0.000
M47.02 Anterior spinal and vertebral artery compression syndromes (Cervical region)
0.008 0.991 0.000
M47.01 Anterior spinal and vertebral artery compression syndromes (Occipito-atlanto-axial region)
0.008 0.991 0.000
M47.00 Anterior spinal and vertebral artery compression syndromes (Multiple sites in spine)
0.008 0.991 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.991 0.008
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.991 0.008
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.008 0.991 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.008 0.992 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.008 0.992 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.008 0.992 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.008 0.992 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.008 0.992 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.008 0.992 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.008 0.992 0.000
M48.9 Spondylopathy, unspecified
0.008 0.992 0.000
M48.8 Other specified spondylopathies
0.008 0.992 0.000
M48.4 Fatigue fracture of vertebra
0.008 0.992 0.000
M48.3 Traumatic spondylopathy
0.008 0.992 0.000
M48.2 Kissing spine
0.008 0.992 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.008 0.992 0.000
I63 Cerebral infarction
0.000 0.992 0.008
M46.8 Other specified inflammatory spondylopathies
0.008 0.992 0.000
M46.5 Other infective spondylopathies
0.008 0.992 0.000
M46.4 Discitis, unspecified
0.008 0.992 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.008 0.992 0.000
M46.2 Osteomyelitis of vertebra
0.008 0.992 0.000
M46.0 Spinal enthesopathy
0.008 0.992 0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.008 0.992 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.992 0.008
I67.1 Cerebral aneurysm, nonruptured
0.000 0.992 0.008
Z95.0 Presence of cardiac pacemaker
0.000 0.992 0.008
I22 Subsequent myocardial infarction
0.000 0.992 0.008
M47.19 Other spondylosis with myelopathy (Site unspecified)
0.007 0.992 0.000
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)
0.007 0.992 0.000
M47.17 Other spondylosis with myelopathy (Lumbosacral region)
0.007 0.992 0.000
M47.16 Other spondylosis with myelopathy (Lumbar region)
0.007 0.992 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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