TreeWAS – Variant ID: rs3751237

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E11.9 Without complications	0.000	0.842	0.158
E11 Non-insulin-dependent diabetes mellitus	0.000	0.865	0.135
E10 Insulin-dependent diabetes mellitus	0.000	0.869	0.131
E10-E14 Diabetes mellitus	0.000	0.872	0.128
E10.9 Without complications	0.000	0.877	0.123
E10.4 With neurological complications	0.000	0.879	0.121
E11.2 With renal complications	0.000	0.882	0.118
E13 Other specified diabetes mellitus	0.000	0.888	0.112
E10.5 With peripheral circulatory complications	0.000	0.891	0.109
E11.1 With ketoacidosis	0.000	0.896	0.104
E11.0 With coma	0.000	0.896	0.104
E10.3 With ophthalmic complications	0.000	0.897	0.103
E10.8 With unspecified complications	0.000	0.897	0.103
E10.0 With coma	0.000	0.897	0.103
E11.8 With unspecified complications	0.000	0.898	0.102
E13.9 Without complications	0.000	0.900	0.100
E11.7 With multiple complications	0.000	0.903	0.097
E10.2 With renal complications	0.000	0.903	0.097
E10.7 With multiple complications	0.000	0.906	0.094
E12 Malnutrition-related diabetes mellitus	0.000	0.908	0.092
E11.4 With neurological complications	0.000	0.914	0.086
E10.1 With ketoacidosis	0.000	0.918	0.082
E13.8 With unspecified complications	0.000	0.920	0.080
E13.7 With multiple complications	0.000	0.920	0.080
E13.6 With other specified complications	0.000	0.920	0.080
E13.5 With peripheral circulatory complications	0.000	0.920	0.080
E13.4 With neurological complications	0.000	0.920	0.080
E13.3 With ophthalmic complications	0.000	0.920	0.080
E13.2 With renal complications	0.000	0.920	0.080
E13.1 With ketoacidosis	0.000	0.920	0.080
E13.0 With coma	0.000	0.920	0.080
E11.6 With other specified complications	0.000	0.921	0.079
E10.6 With other specified complications	0.000	0.924	0.076
E12.9 Without complications	0.000	0.934	0.066
E12.8 With unspecified complications	0.000	0.934	0.066
E12.7 With multiple complications	0.000	0.934	0.066
E12.6 With other specified complications	0.000	0.934	0.066
E12.5 With peripheral circulatory complications	0.000	0.934	0.066
E12.4 With neurological complications	0.000	0.934	0.066
E12.3 With ophthalmic complications	0.000	0.934	0.066
E12.2 With renal complications	0.000	0.934	0.066
E12.1 With ketoacidosis	0.000	0.934	0.066
E12.0 With coma	0.000	0.934	0.066
E14 Unspecified diabetes mellitus	0.000	0.947	0.053
E11.3 With ophthalmic complications	0.000	0.947	0.053
E11.5 With peripheral circulatory complications	0.000	0.950	0.050
E14.4 With neurological complications	0.000	0.961	0.039
E14.7 With multiple complications	0.000	0.962	0.038
E14.5 With peripheral circulatory complications	0.000	0.962	0.038
E14.2 Withrenal complications	0.000	0.962	0.038
E14.1 With ketoacidosis	0.000	0.962	0.038
E14.0 With coma	0.000	0.962	0.038
E14.6 With other specified complications	0.000	0.962	0.038
E14.3 With ophthalmic complications	0.000	0.962	0.038
E14.8 With unspecified complications	0.000	0.966	0.034
Q20-Q28 Congenital malformations of the circulatory system	0.031	0.969	0.000
Q24 Other congenital malformations of heart	0.031	0.969	0.000
Q28 Other congenital malformations of circulatory system	0.031	0.969	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.030	0.970	0.000
Q25 Congenital malformations of great arteries	0.029	0.971	0.000
Q24.8 Other specified congenital malformations of heart	0.029	0.971	0.000
Q27 Other congenital malformations of peripheral vascular system	0.026	0.974	0.000
Q21 Congenital malformations of cardiac septa	0.025	0.975	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.025	0.975	0.000
Q25.0 Patent ductus arteriosus	0.025	0.975	0.000
Q24.6 Congenital heart block	0.025	0.975	0.000
Q25.1 Coarctation of aorta	0.024	0.976	0.000
Q24.5 Malformation of coronary vessels	0.024	0.976	0.000
Q25.3 Stenosis of aorta	0.024	0.976	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.024	0.976	0.000
Q27.3 Peripheral arteriovenous malformation	0.023	0.977	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.023	0.977	0.000
Q28.3 Other malformations of cerebral vessels	0.023	0.977	0.000
Q26 Congenital malformations of great veins	0.022	0.977	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.022	0.977	0.000
Q24.4 Congenital subaortic stenosis	0.022	0.978	0.000
Q24.3 Pulmonary infundibular stenosis	0.022	0.978	0.000
Q24.2 Cor triatriatum	0.022	0.978	0.000
Q24.1 Levocardia	0.022	0.978	0.000
Q24.0 Dextrocardia	0.022	0.978	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.022	0.978	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.022	0.978	0.000
Q28.1 Other malformations of precerebral vessels	0.022	0.978	0.000
F10.3 Withdrawal state	0.022	0.978	0.000
Q25.4 Other congenital malformations of aorta	0.022	0.978	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.021	0.979	0.000
Q25.8 Other congenital malformations of great arteries	0.021	0.979	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.021	0.979	0.000
Q25.5 Atresia of pulmonary artery	0.021	0.979	0.000
Q25.2 Atresia of aorta	0.021	0.979	0.000
F10.2 Dependence syndrome	0.021	0.979	0.000
Q25.6 Stenosis of pulmonary artery	0.021	0.979	0.000
I08.0 Disorders of both mitral and aortic valves	0.000	0.979	0.021
Q21.3 Tetralogy of Fallot	0.020	0.980	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.020	0.980	0.000
Q21.0 Ventricular septal defect	0.020	0.980	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.020	0.980	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.019	0.981	0.000
Q27.4 Congenital phlebectasia	0.019	0.981	0.000
Q27.2 Other congenital malformations of renal artery	0.019	0.981	0.000
Q27.1 Congenital renal artery stenosis	0.019	0.981	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.019	0.981	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.019	0.981	0.000
Q22.1 Congenital pulmonary valve stenosis	0.018	0.981	0.000
Q21.8 Other congenital malformations of cardiac septa	0.018	0.981	0.000
Q21.4 Aortopulmonary septal defect	0.018	0.981	0.000
Q21.2 Atrioventricular septal defect	0.018	0.981	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.017	0.983	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.017	0.983	0.000
Q22.6 Hypoplastic right heart syndrome	0.017	0.983	0.000
Q22.5 Ebstein's anomaly	0.017	0.983	0.000
Q22.4 Congenital tricuspid stenosis	0.017	0.983	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.017	0.983	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.017	0.983	0.000
Q22.0 Pulmonary valve atresia	0.017	0.983	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.016	0.984	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.016	0.984	0.000
Q20.6 Isomerism of atrial appendages	0.016	0.984	0.000
Q20.5 Discordant atrioventricular connexion	0.016	0.984	0.000
Q20.4 Double inlet ventricle	0.016	0.984	0.000
Q20.3 Discordant ventriculoarterial connexion	0.016	0.984	0.000
Q20.2 Double outlet left ventricle	0.016	0.984	0.000
Q20.1 Double outlet right ventricle	0.016	0.984	0.000
Q20.0 Common arterial trunk	0.016	0.984	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.016	0.984	0.000
Q26.8 Other congenital malformations of great veins	0.016	0.984	0.000
Q26.6 Portal vein-hepatic artery fistula	0.016	0.984	0.000
Q26.5 Anomalous portal venous connexion	0.016	0.984	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.016	0.984	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.016	0.984	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.016	0.984	0.000
Q26.1 Persistent left superior vena cava	0.016	0.984	0.000
Q26.0 Congenital stenosis of vena cava	0.016	0.984	0.000
Q21.1 Atrial septal defect	0.016	0.984	0.000
F10.7 Residual and late-onset psychotic disorder	0.016	0.984	0.000
F10.9 Unspecified mental and behavioural disorder	0.016	0.984	0.000
F10.4 Withdrawal state with delirium	0.015	0.985	0.000
F10.5 Psychotic disorder	0.014	0.986	0.000
F10.8 Other mental and behavioural disorders	0.014	0.986	0.000
R59.1 Generalised enlarged lymph nodes	0.014	0.986	0.000
F10.1 Harmful use	0.014	0.986	0.000
F10.6 Amnesic syndrome	0.014	0.986	0.000
Q23 Congenital malformations of aortic and mitral valves	0.013	0.986	0.000
E14.9 Without complications	0.000	0.987	0.013
S02.10 Fracture of base of skull (closed)	0.011	0.989	0.000
I08 Multiple valve diseases	0.000	0.989	0.011
R22.2 Localised swelling, mass and lump, trunk	0.010	0.990	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.010	0.990	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.010	0.990	0.000
Q23.4 Hypoplastic left heart syndrome	0.010	0.990	0.000
Q23.3 Congenital mitral insufficiency	0.010	0.990	0.000
Q23.2 Congenital mitral stenosis	0.010	0.990	0.000
S02.1 Fracture of base of skull	0.010	0.990	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.010	0.990	0.000
S02 Fracture of skull and facial bones	0.010	0.990	0.000
S02.4 Fracture of malar and maxillary bones	0.010	0.990	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.990	0.010
S02.2 Fracture of nasal bones	0.009	0.991	0.000
S02.0 Fracture of vault of skull	0.009	0.991	0.000
Q23.0 Congenital stenosis of aortic valve	0.008	0.992	0.000
S02.8 Fractures of other skull and facial bones	0.008	0.992	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.992	0.008
S02.9 Fracture of skull and facial bones, part unspecified	0.008	0.992	0.000
I08.8 Other multiple valve diseases	0.000	0.992	0.008
S02.20 Fracture of nasal bones (closed)	0.008	0.992	0.000
S02.00 Fracture of vault of skull (closed)	0.008	0.992	0.000
I08.9 Multiple valve disease, unspecified	0.000	0.992	0.008
S02.5 Fracture of tooth	0.008	0.992	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.007	0.992	0.000
S02.11 Fracture of base of skull (open)	0.007	0.992	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.007	0.993	0.000
S02.7 Multiple fractures involving skull and facial bones	0.007	0.993	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.007	0.993	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.007	0.993	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.993	0.007
D12.0 Caecum	0.007	0.993	0.000
S02.21 Fracture of nasal bones (open)	0.006	0.993	0.000
S02.01 Fracture of vault of skull (open)	0.006	0.993	0.000
S02.81 Fractures of other skull and facial bones (open)	0.006	0.994	0.000
S02.50 Fracture of tooth (closed)	0.006	0.994	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.994	0.006
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.006	0.994	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.994	0.006
S90.9 Superficial injury of ankle and foot, unspecified	0.006	0.994	0.000
R59 Enlarged lymph nodes	0.006	0.994	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.994	0.006
S90 Superficial injury of ankle and foot	0.006	0.994	0.000
S02.51 Fracture of tooth (open)	0.006	0.994	0.000
S93.1 Dislocation of toe(s)	0.006	0.994	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.006	0.994	0.000
M54.39 Sciatica (Site unspecified)	0.006	0.994	0.000
S02.3 Fracture of orbital floor	0.005	0.994	0.000
S69.9 Unspecified injury of wrist and hand	0.006	0.994	0.000
S90.8 Other superficial injuries of ankle and foot	0.006	0.994	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.006	0.994	0.000
S91 Open wound of ankle and foot	0.006	0.994	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.005	0.995	0.000
S90-S99 Injuries to the ankle and foot	0.005	0.995	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.005	0.995	0.000
S02.6 Fracture of mandible	0.005	0.995	0.000
Q23.1 Congenital insufficiency of aortic valve	0.005	0.995	0.001
T42.4 Benzodiazepines	0.000	0.995	0.005
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.995	0.005
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.995	0.005
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.995	0.005
T90.4 Sequelae of injury of eye and orbit	0.005	0.995	0.000
I05-I09 Chronic rheumatic heart diseases	0.000	0.995	0.005
S91.0 Open wound of ankle	0.005	0.995	0.000
S91.2 Open wound of toe(s) with damage to nail	0.005	0.995	0.000
S93.0 Dislocation of ankle joint	0.005	0.995	0.000
R59.9 Enlarged lymph nodes, unspecified	0.005	0.995	0.000
T50.8 Diagnostic agents	0.000	0.995	0.005
T50.7 Analeptics and opioid receptor antagonists	0.000	0.995	0.005
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.995	0.005
T50.5 Appetite depressants	0.000	0.995	0.005
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.995	0.005
T50.1 Loop [high-ceiling] diuretics	0.000	0.995	0.005
T50.0 Mineralocorticoids and their antagonists	0.000	0.995	0.005
T46.1 Calcium-channel blockers	0.000	0.995	0.005
F99 Mental disorder, not otherwise specified	0.000	0.995	0.005
M50.1 Cervical disk disorder with radiculopathy	0.000	0.995	0.005
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.995	0.005
S91.3 Open wound of other parts of foot	0.005	0.995	0.000
T42.1 Iminostilbenes	0.000	0.995	0.005
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.995	0.004
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.005	0.995	0.000
M43.1 Spondylolisthesis	0.005	0.995	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.004	0.995	0.000
T50.4 Drugs affecting uric acid metabolism	0.000	0.995	0.004
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.995	0.004
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.995	0.004
T46.7 Peripheral vasodilators	0.000	0.995	0.004
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.995	0.004
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.995	0.004
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.995	0.004
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.995	0.004
H66.9 Otitis media, unspecified	0.000	0.995	0.005
S90.7 Multiple superficial injuries of ankle and foot	0.004	0.995	0.000
S90.2 Contusion of toe(s) with damage to nail	0.004	0.995	0.000
S90.1 Contusion of toe(s) without damage to nail	0.004	0.995	0.000
S93.4 Sprain and strain of ankle	0.004	0.996	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.004	0.996	0.000
S93.5 Sprain and strain of toe(s)	0.004	0.996	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.004	0.996	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.004	0.996	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.004	0.996	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.996	0.004
S02.31 Fracture of orbital floor (open)	0.004	0.996	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.004	0.996	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.004	0.996	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.004	0.996	0.000
S91.7 Multiple open wounds of ankle and foot	0.004	0.996	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.996	0.004
I09 Other rheumatic heart diseases	0.000	0.996	0.004
S98 Traumatic amputation of ankle and foot	0.004	0.996	0.000
S97 Crushing injury of ankle and foot	0.004	0.996	0.000
S95 Injury of blood vessels at ankle and foot level	0.004	0.996	0.000
S94 Injury of nerves at ankle and foot level	0.004	0.996	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.004	0.996	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.996	0.004
R59.0 Localised enlarged lymph nodes	0.004	0.996	0.000
S90.0 Contusion of ankle	0.004	0.996	0.000
F11 Mental and behavioural disorders due to use of opioids	0.004	0.996	0.000
I12.9 Hypertensive renal disease without renal failure	0.000	0.996	0.004
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.996	0.004
S02.61 Fracture of mandible (open)	0.004	0.996	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.004	0.996	0.000
S99 Other and unspecified injuries of ankle and foot	0.004	0.996	0.000
M54.3 Sciatica	0.004	0.996	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.996	0.004
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.996	0.004
S91.1 Open wound of toe(s) without damage to nail	0.004	0.996	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.996	0.004
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.996	0.004
T42.3 Barbiturates	0.000	0.996	0.004
T42.2 Succinimides and oxazolidinediones	0.000	0.996	0.004
F10.0 Acute intoxication	0.004	0.996	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.996	0.004
I05 Rheumatic mitral valve diseases	0.000	0.996	0.004
M54.36 Sciatica (Lumbar region)	0.004	0.996	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.004	0.996	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.996	0.004
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.996	0.004
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.996	0.004
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.996	0.004
S92 Fracture of foot, except ankle	0.004	0.996	0.000
F15.1 Harmful use	0.004	0.996	0.000
T45.0 Antiallergic and antiemetic drugs	0.000	0.996	0.004
S90.3 Contusion of other and unspecified parts of foot	0.004	0.996	0.000
T42.0 Hydantoin derivatives	0.000	0.996	0.004
T45.2 Vitamins, not elsewhere classified	0.000	0.996	0.004
I09.9 Rheumatic heart disease, unspecified	0.000	0.996	0.004
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.996	0.004
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.004	0.996	0.000
I07 Rheumatic tricuspid valve diseases	0.000	0.996	0.004
F12.2 Dependence syndrome	0.003	0.996	0.000
F15.9 Unspecified mental and behavioural disorder	0.003	0.996	0.000
F15.8 Other mental and behavioural disorders	0.003	0.996	0.000
F15.7 Residual and late-onset psychotic disorder	0.003	0.996	0.000
F15.6 Amnesic syndrome	0.003	0.996	0.000
F15.5 Psychotic disorder	0.003	0.996	0.000
F15.4 Withdrawal state with delirium	0.003	0.996	0.000
F15.3 Withdrawal state	0.003	0.996	0.000
F15.2 Dependence syndrome	0.003	0.996	0.000
F15.0 Acute intoxication	0.003	0.996	0.000
I06 Rheumatic aortic valve diseases	0.000	0.996	0.003
T36 Poisoning by systemic antibiotics	0.000	0.996	0.003
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.003	0.996	0.000
M43.15 Spondylolisthesis (Thoracolumbar region)	0.003	0.996	0.000
M43.14 Spondylolisthesis (Thoracic region)	0.003	0.996	0.000
M43.13 Spondylolisthesis (Cervicothoracic region)	0.003	0.996	0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.003	0.996	0.000
M43.10 Spondylolisthesis (Multiple sites in spine)	0.003	0.996	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.996	0.003
F13.2 Dependence syndrome	0.003	0.996	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.996	0.003
T45.8 Other primarily systemic and haematological agents	0.000	0.996	0.003
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.996	0.003
T45.6 Fibrinolysis-affecting drugs	0.000	0.996	0.003
T45.4 Iron and its compounds	0.000	0.996	0.003
T45.3 Enzymes, not elsewhere classified	0.000	0.996	0.003
M43.12 Spondylolisthesis (Cervical region)	0.003	0.997	0.000
F11.1 Harmful use	0.003	0.997	0.000
I12 Hypertensive renal disease	0.000	0.997	0.003
S93.40 Sprain of unspecified ligament of ankle	0.003	0.997	0.000
F12.9 Unspecified mental and behavioural disorder	0.003	0.997	0.000
F12.8 Other mental and behavioural disorders	0.003	0.997	0.000
F12.7 Residual and late-onset psychotic disorder	0.003	0.997	0.000
F12.6 Amnesic syndrome	0.003	0.997	0.000
F12.5 Psychotic disorder	0.003	0.997	0.000
F12.4 Withdrawal state with delirium	0.003	0.997	0.000
F12.3 Withdrawal state	0.003	0.997	0.000
F12.0 Acute intoxication	0.003	0.997	0.000
F13.9 Unspecified mental and behavioural disorder	0.003	0.997	0.000
F13.8 Other mental and behavioural disorders	0.003	0.997	0.000
F13.7 Residual and late-onset psychotic disorder	0.003	0.997	0.000
F13.6 Amnesic syndrome	0.003	0.997	0.000
F13.5 Psychotic disorder	0.003	0.997	0.000
F13.4 Withdrawal state with delirium	0.003	0.997	0.000
F13.3 Withdrawal state	0.003	0.997	0.000
F13.1 Harmful use	0.003	0.997	0.000
F13.0 Acute intoxication	0.003	0.997	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.997	0.003
S92.0 Fracture of calcaneus	0.003	0.997	0.000
T43.9 Psychotropic drug, unspecified	0.000	0.997	0.003
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.997	0.003
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.997	0.003
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.997	0.003
C45.9 Mesothelioma, unspecified	0.003	0.997	0.000
F12.1 Harmful use	0.003	0.997	0.000
F14.9 Unspecified mental and behavioural disorder	0.003	0.997	0.000
F14.8 Other mental and behavioural disorders	0.003	0.997	0.000
F14.7 Residual and late-onset psychotic disorder	0.003	0.997	0.000
F14.6 Amnesic syndrome	0.003	0.997	0.000
F14.5 Psychotic disorder	0.003	0.997	0.000
F14.4 Withdrawal state with delirium	0.003	0.997	0.000
F14.3 Withdrawal state	0.003	0.997	0.000
F14.2 Dependence syndrome	0.003	0.997	0.000
F14.1 Harmful use	0.003	0.997	0.000
F14.0 Acute intoxication	0.003	0.997	0.000
F16.9 Unspecified mental and behavioural disorder	0.003	0.997	0.000
F16.8 Other mental and behavioural disorders	0.003	0.997	0.000
F16.7 Residual and late-onset psychotic disorder	0.003	0.997	0.000
F16.6 Amnesic syndrome	0.003	0.997	0.000
F16.5 Psychotic disorder	0.003	0.997	0.000
F16.4 Withdrawal state with delirium	0.003	0.997	0.000
F16.3 Withdrawal state	0.003	0.997	0.000
F16.2 Dependence syndrome	0.003	0.997	0.000
F16.1 Harmful use	0.003	0.997	0.000
F16.0 Acute intoxication	0.003	0.997	0.000
F18.9 Unspecified mental and behavioural disorder	0.003	0.997	0.000
F18.8 Other mental and behavioural disorders	0.003	0.997	0.000
F18.7 Residual and late-onset psychotic disorder	0.003	0.997	0.000
F18.6 Amnesic syndrome	0.003	0.997	0.000
F18.5 Psychotic disorder	0.003	0.997	0.000
F18.4 Withdrawal state with delirium	0.003	0.997	0.000
F18.3 Withdrawal state	0.003	0.997	0.000
F18.2 Dependence syndrome	0.003	0.997	0.000
F18.1 Harmful use	0.003	0.997	0.000
F18.0 Acute intoxication	0.003	0.997	0.000
S99.9 Unspecified injury of ankle and foot	0.003	0.997	0.000
I09.8 Other specified rheumatic heart diseases	0.000	0.997	0.003
I09.2 Chronic rheumatic pericarditis	0.000	0.997	0.003
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.997	0.003
I09.0 Rheumatic myocarditis	0.000	0.997	0.003
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.997	0.003
J81 Pulmonary oedema	0.003	0.997	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.003	0.997	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.003	0.997	0.000
S94.8 Injury of other nerves at ankle and foot level	0.003	0.997	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.003	0.997	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.003	0.997	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.003	0.997	0.000
S94.1 Injury of medial plantar nerve	0.003	0.997	0.000
S94.0 Injury of lateral plantar nerve	0.003	0.997	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.003	0.997	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.003	0.997	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.003	0.997	0.000
S95.2 Injury of dorsal vein of foot	0.003	0.997	0.000
S95.1 Injury of plantar artery of foot	0.003	0.997	0.000
S95.0 Injury of dorsal artery of foot	0.003	0.997	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.003	0.997	0.000
S97.1 Crushing injury of toe(s)	0.003	0.997	0.000
S97.0 Crushing injury of ankle	0.003	0.997	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.003	0.997	0.000
S98.3 Traumatic amputation of other parts of foot	0.003	0.997	0.000
S98.2 Traumatic amputation of two or more toes	0.003	0.997	0.000
S98.1 Traumatic amputation of one toe	0.003	0.997	0.000
S98.0 Traumatic amputation of foot at ankle level	0.003	0.997	0.000
S92.1 Fracture of talus	0.003	0.997	0.000
F11.9 Unspecified mental and behavioural disorder	0.003	0.997	0.000
F11.8 Other mental and behavioural disorders	0.003	0.997	0.000
F11.7 Residual and late-onset psychotic disorder	0.003	0.997	0.000
F11.6 Amnesic syndrome	0.003	0.997	0.000
F11.5 Psychotic disorder	0.003	0.997	0.000
F11.4 Withdrawal state with delirium	0.003	0.997	0.000
F11.3 Withdrawal state	0.003	0.997	0.000
F11.0 Acute intoxication	0.003	0.997	0.000
F19.2 Dependence syndrome	0.003	0.997	0.000
S92.5 Fracture of other toe	0.003	0.997	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.003	0.997	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.003	0.997	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.003	0.997	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.003	0.997	0.000
M54.35 Sciatica (Thoracolumbar region)	0.003	0.997	0.000
M54.34 Sciatica-Thoracic	0.003	0.997	0.000
M54.33 Sciatica-Cervicothoracic	0.003	0.997	0.000
M54.32 Sciatica-Cervical	0.003	0.997	0.000
M54.31 Sciatica-Occipit-atl-axl	0.003	0.997	0.000
M54.30 Sciatica (Multiple sites in spine)	0.003	0.997	0.000
S99.7 Multiple injuries of ankle and foot	0.003	0.997	0.000
C45.7 Mesothelioma of other sites	0.003	0.997	0.000
I05.8 Other mitral valve diseases	0.000	0.997	0.003
F19.9 Unspecified mental and behavioural disorder	0.003	0.997	0.000
F19.8 Other mental and behavioural disorders	0.003	0.997	0.000
F19.7 Residual and late-onset psychotic disorder	0.003	0.997	0.000
F19.6 Amnesic syndrome	0.003	0.997	0.000
F19.5 Psychotic disorder	0.003	0.997	0.000
F19.4 Withdrawal state with delirium	0.003	0.997	0.000
F19.3 Withdrawal state	0.003	0.997	0.000
F19.0 Acute intoxication	0.003	0.997	0.000
T41.5 Therapeutic gases	0.000	0.997	0.003
T41.4 Anaesthetic, unspecified	0.000	0.997	0.003
T41.3 Local anaesthetics	0.000	0.997	0.003
T41.2 Other and unspecified general anaesthetics	0.000	0.997	0.003
T41.1 Intravenous anaesthetics	0.000	0.997	0.003
T41.0 Inhaled anaesthetics	0.000	0.997	0.003
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.997	0.003
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.997	0.003
T47.7 Emetics	0.000	0.997	0.003
T47.6 Antidiarrhoeal drugs	0.000	0.997	0.003
T47.5 Digestants	0.000	0.997	0.003
T47.4 Other laxatives	0.000	0.997	0.003
T47.3 Saline and osmotic laxatives	0.000	0.997	0.003
T47.2 Stimulant laxatives	0.000	0.997	0.003
T47.0 Histamine H(2)-receptor antagonists	0.000	0.997	0.003
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.997	0.003
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.997	0.003
T48.5 Anti-common-cold drugs	0.000	0.997	0.003
T48.4 Expectorants	0.000	0.997	0.003
T48.3 Antitussives	0.000	0.997	0.003
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.997	0.003
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.997	0.003
T48.0 Oxytocic drugs	0.000	0.997	0.003
T49.9 Topical agent, unspecified	0.000	0.997	0.003
T49.8 Other topical agents	0.000	0.997	0.003
T49.7 Dental drugs, topically applied	0.000	0.997	0.003
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.997	0.003
T49.5 Ophthalmological drugs and preparations	0.000	0.997	0.003
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.997	0.003
T49.3 Emollients, demulcents and protectants	0.000	0.997	0.003
T49.2 Local astringents and local detergents	0.000	0.997	0.003
T49.1 Antipruritics	0.000	0.997	0.003
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.997	0.003
C45 Mesothelioma	0.003	0.997	0.000
M43.19 Spondylolisthesis (Site unspecified)	0.003	0.997	0.000
S92.4 Fracture of great toe	0.003	0.997	0.000
S92.9 Fracture of foot, unspecified	0.003	0.997	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.997	0.003
I05.9 Mitral valve disease, unspecified	0.000	0.997	0.003
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.003	0.997	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.997	0.003
S92.00 Fracture of calcaneus (closed)	0.003	0.997	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.997	0.003
C49.0 Connective and soft tissue of head, face and neck	0.003	0.997	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.997	0.003
T43.6 Psychostimulants with abuse potential	0.000	0.997	0.003
M54.37 Sciatica (Lumbosacral region)	0.003	0.997	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.997	0.003
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.997	0.003
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.997	0.003
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.997	0.003
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.997	0.003
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.997	0.003
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.997	0.003
T44.0 Anticholinesterase agents	0.000	0.997	0.003
S92.51 Fracture of other toe (open)	0.003	0.997	0.000
I07.9 Tricuspid valve disease, unspecified	0.000	0.997	0.003
I07.8 Other tricuspid valve diseases	0.000	0.997	0.003
I07.2 Tricuspid stenosis with insufficiency	0.000	0.997	0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations