TreeWAS – Variant ID: rs3757247

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
C44 Other malignant neoplasms of skin	0.000	0.000	1.000
C44.6 Skin of upper limb, including shoulder	0.000	0.000	1.000
C44.5 Skin of trunk	0.000	0.002	0.998
C44.7 Skin of lower limb, including hip	0.000	0.044	0.956
C44.1 Skin of eyelid, including canthus	0.000	0.051	0.949
C44.2 Skin of ear and external auricular canal	0.000	0.065	0.935
C44.4 Skin of scalp and neck	0.000	0.162	0.838
C67.9 Bladder, unspecified	0.794	0.206	0.000
C67 Malignant neoplasm of bladder	0.788	0.212	0.000
C67.6 Ureteric orifice	0.757	0.243	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.000	0.249	0.751
E03 Other hypothyroidism	0.742	0.258	0.000
C44.0 Skin of lip	0.000	0.281	0.719
C44.8 Overlapping lesion of skin	0.000	0.283	0.717
J45.9 Asthma, unspecified	0.000	0.288	0.712
C67.3 Anterior wall of bladder	0.665	0.335	0.000
C67.2 Lateral wall of bladder	0.662	0.338	0.000
C67.5 Bladder neck	0.655	0.345	0.000
C67.4 Posterior wall of bladder	0.642	0.358	0.000
C67.0 Trigone of bladder	0.631	0.369	0.000
E03.1 Congenital hypothyroidism without goitre	0.610	0.390	0.000
C67.1 Dome of bladder	0.595	0.405	0.000
E00-E07 Disorders of thyroid gland	0.589	0.411	0.000
E06 Thyroiditis	0.574	0.426	0.000
C67.7 Urachus	0.565	0.435	0.000
E06.3 Autoimmune thyroiditis	0.561	0.439	0.000
C44.3 Skin of other and unspecified parts of face	0.000	0.453	0.547
C67.8 Overlapping lesion of bladder	0.546	0.453	0.000
E03.5 Myxoedema coma	0.532	0.468	0.000
E03.4 Atrophy of thyroid (acquired)	0.532	0.468	0.000
E03.3 Postinfectious hypothyroidism	0.532	0.468	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.532	0.468	0.000
E03.8 Other specified hypothyroidism	0.474	0.526	0.000
E06.5 Other chronic thyroiditis	0.458	0.542	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.424	0.575	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.423	0.577	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.423	0.577	0.000
E00 Congenital iodine-deficiency syndrome	0.423	0.577	0.000
E06.4 Drug-induced thyroiditis	0.411	0.588	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.411	0.588	0.000
E06.0 Acute thyroiditis	0.411	0.588	0.000
E06.1 Subacute thyroiditis	0.411	0.589	0.000
E10-E14 Diabetes mellitus	0.410	0.590	0.000
E10 Insulin-dependent diabetes mellitus	0.407	0.593	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.402	0.598	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.393	0.607	0.000
E10.3 With ophthalmic complications	0.382	0.618	0.000
E06.9 Thyroiditis, unspecified	0.380	0.620	0.000
E10.4 With neurological complications	0.371	0.629	0.000
E14 Unspecified diabetes mellitus	0.365	0.635	0.000
E10.9 Without complications	0.364	0.636	0.000
E13 Other specified diabetes mellitus	0.340	0.660	0.000
E14.8 With unspecified complications	0.334	0.666	0.000
C64-C68 Malignant neoplasms of urinary tract	0.332	0.668	0.000
E14.3 With ophthalmic complications	0.330	0.670	0.000
E10.1 With ketoacidosis	0.330	0.670	0.000
E05.9 Thyrotoxicosis, unspecified	0.330	0.670	0.000
E10.5 With peripheral circulatory complications	0.317	0.683	0.000
E11 Non-insulin-dependent diabetes mellitus	0.317	0.683	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.303	0.697	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.303	0.697	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.303	0.697	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.303	0.697	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.303	0.697	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.303	0.697	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.303	0.697	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.303	0.697	0.000
E11.6 With other specified complications	0.303	0.697	0.000
E13.3 With ophthalmic complications	0.295	0.705	0.000
E12 Malnutrition-related diabetes mellitus	0.294	0.706	0.000
E14.2 Withrenal complications	0.290	0.710	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.290	0.710	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.287	0.713	0.000
E07 Other disorders of thyroid	0.287	0.713	0.000
E10.2 With renal complications	0.284	0.716	0.000
E14.6 With other specified complications	0.282	0.718	0.000
E05.5 Thyroid crisis or storm	0.282	0.718	0.000
E05.4 Thyrotoxicosis factitia	0.282	0.718	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.282	0.718	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.282	0.718	0.000
E10.7 With multiple complications	0.280	0.720	0.000
E50-E64 Other nutritional deficiencies	0.278	0.722	0.000
C65 Malignant neoplasm of renal pelvis	0.273	0.726	0.000
E10.6 With other specified complications	0.269	0.730	0.000
E10.0 With coma	0.268	0.732	0.000
E11.4 With neurological complications	0.267	0.733	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.265	0.735	0.000
E40-E46 Malnutrition	0.264	0.736	0.000
E14.1 With ketoacidosis	0.262	0.738	0.000
E14.0 With coma	0.262	0.738	0.000
E14.7 With multiple complications	0.262	0.738	0.000
E11.0 With coma	0.262	0.738	0.000
E05.8 Other thyrotoxicosis	0.260	0.740	0.000
E14.4 With neurological complications	0.252	0.748	0.000
E11.7 With multiple complications	0.245	0.755	0.000
E11.3 With ophthalmic complications	0.244	0.756	0.000
E10.8 With unspecified complications	0.244	0.756	0.000
E13.8 With unspecified complications	0.244	0.756	0.000
E13.7 With multiple complications	0.244	0.756	0.000
E13.6 With other specified complications	0.244	0.756	0.000
E13.5 With peripheral circulatory complications	0.244	0.756	0.000
E13.4 With neurological complications	0.244	0.756	0.000
E13.2 With renal complications	0.244	0.756	0.000
E13.1 With ketoacidosis	0.244	0.756	0.000
E13.0 With coma	0.244	0.756	0.000
E13.9 Without complications	0.235	0.765	0.000
E14.5 With peripheral circulatory complications	0.219	0.781	0.000
E63 Other nutritional deficiencies	0.217	0.782	0.000
J45 Asthma	0.000	0.784	0.216
E58 Dietary calcium deficiency	0.214	0.786	0.000
E12.9 Without complications	0.211	0.789	0.000
E12.8 With unspecified complications	0.211	0.789	0.000
E12.7 With multiple complications	0.211	0.789	0.000
E12.6 With other specified complications	0.211	0.789	0.000
E12.5 With peripheral circulatory complications	0.211	0.789	0.000
E12.4 With neurological complications	0.211	0.789	0.000
E12.3 With ophthalmic complications	0.211	0.789	0.000
E12.2 With renal complications	0.211	0.789	0.000
E12.1 With ketoacidosis	0.211	0.789	0.000
E12.0 With coma	0.211	0.789	0.000
E16 Other disorders of pancreatic internal secretion	0.209	0.791	0.000
E15 Nondiabetic hypoglycaemic coma	0.208	0.792	0.000
E54 Ascorbic acid deficiency	0.207	0.793	0.000
E07.1 Dyshormogenetic goitre	0.206	0.794	0.000
E07.0 Hypersecretion of calcitonin	0.206	0.794	0.000
C68.0 Urethra	0.205	0.795	0.000
E65-E68 Obesity and other hyperalimentation	0.205	0.795	0.000
C68.9 Urinary organ, unspecified	0.205	0.795	0.000
E11.1 With ketoacidosis	0.204	0.796	0.000
E53 Deficiency of other B group vitamins	0.201	0.799	0.000
E51 Thiamine deficiency	0.200	0.800	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.200	0.800	0.000
E50 Vitamin A deficiency	0.200	0.800	0.000
E60 Dietary zinc deficiency	0.200	0.800	0.000
E59 Dietary selenium deficiency	0.200	0.800	0.000
E52 Niacin deficiency [pellagra]	0.200	0.800	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.197	0.803	0.000
E56 Other vitamin deficiencies	0.194	0.806	0.000
C68.8 Overlapping lesion of urinary organs	0.190	0.810	0.000
C68.1 Paraurethral glands	0.190	0.810	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.189	0.810	0.000
E45 Retarded development following protein-energy malnutrition	0.189	0.810	0.000
E43 Unspecified severe protein-energy malnutrition	0.189	0.810	0.000
E42 Marasmic kwashiorkor	0.189	0.810	0.000
E41 Nutritional marasmus	0.189	0.810	0.000
E40 Kwashiorkor	0.189	0.810	0.000
C66 Malignant neoplasm of ureter	0.185	0.815	0.000
E11.8 With unspecified complications	0.183	0.817	0.000
E61 Deficiency of other nutrient elements	0.182	0.818	0.000
E63.9 Nutritional deficiency, unspecified	0.174	0.826	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.000	0.827	0.172
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.172	0.828	0.000
E07.8 Other specified disorders of thyroid	0.165	0.835	0.000
E46 Unspecified protein-energy malnutrition	0.165	0.835	0.000
E16.2 Hypoglycaemia, unspecified	0.162	0.838	0.000
E11.2 With renal complications	0.162	0.838	0.000
E65 Localised adiposity	0.159	0.841	0.000
E11.5 With peripheral circulatory complications	0.158	0.842	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.157	0.843	0.000
E55 Vitamin D deficiency	0.156	0.844	0.000
E63.8 Other specified nutritional deficiencies	0.156	0.844	0.000
E63.1 Imbalance of constituents of food intake	0.156	0.844	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.156	0.844	0.000
E53.9 Vitamin B deficiency, unspecified	0.156	0.844	0.000
J45.8 Mixed asthma	0.000	0.846	0.154
J45.1 Nonallergic asthma	0.000	0.847	0.153
E16.9 Disorder of pancreatic internal secretion, unspecified	0.150	0.850	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.150	0.850	0.000
E16.4 Abnormal secretion of gastrin	0.150	0.850	0.000
E16.3 Increased secretion of glucagon	0.150	0.850	0.000
E67 Other hyperalimentation	0.147	0.853	0.000
E68 Sequelae of hyperalimentation	0.147	0.853	0.000
E53.1 Pyridoxine deficiency	0.144	0.855	0.000
E53.0 Riboflavin deficiency	0.144	0.855	0.000
E51.2 Wernicke's encephalopathy	0.143	0.856	0.000
E51.9 Thiamine deficiency, unspecified	0.143	0.856	0.000
E51.8 Other manifestations of thiamine deficiency	0.143	0.856	0.000
E51.1 Beriberi	0.143	0.856	0.000
E50.9 Vitamin A deficiency, unspecified	0.143	0.857	0.000
E50.8 Other manifestations of vitamin A deficiency	0.143	0.857	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.143	0.857	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.143	0.857	0.000
E50.5 Vitamin A deficiency with night blindness	0.143	0.857	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.143	0.857	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.143	0.857	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.143	0.857	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.143	0.857	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.143	0.857	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.143	0.857	0.000
E64.8 Sequelae of other nutritional deficiencies	0.143	0.857	0.000
E64.3 Sequelae of rickets	0.143	0.857	0.000
E64.2 Sequelae of vitamin C deficiency	0.143	0.857	0.000
E64.1 Sequelae of vitamin A deficiency	0.143	0.857	0.000
E64.0 Sequelae of protein-energy malnutrition	0.143	0.857	0.000
E07.9 Disorder of thyroid, unspecified	0.142	0.858	0.000
E56.9 Vitamin deficiency, unspecified	0.139	0.860	0.000
E56.8 Deficiency of other vitamins	0.139	0.860	0.000
E56.0 Deficiency of vitamin E	0.139	0.860	0.000
E44.1 Mild protein-energy malnutrition	0.136	0.864	0.000
E44.0 Moderate protein-energy malnutrition	0.136	0.864	0.000
E56.1 Deficiency of vitamin K	0.134	0.866	0.000
E53.8 Deficiency of other specified B group vitamins	0.132	0.868	0.000
E61.2 Magnesium deficiency	0.131	0.869	0.000
E61.9 Deficiency of nutrient element, unspecified	0.130	0.870	0.000
E61.8 Deficiency of other specified nutrient elements	0.130	0.870	0.000
E61.7 Deficiency of multiple nutrient elements	0.130	0.870	0.000
E61.6 Vanadium deficiency	0.130	0.870	0.000
E61.5 Molybdenum deficiency	0.130	0.870	0.000
E61.4 Chromium deficiency	0.130	0.870	0.000
E61.3 Manganese deficiency	0.130	0.870	0.000
E61.0 Copper deficiency	0.130	0.870	0.000
E16.1 Other hypoglycaemia	0.126	0.874	0.000
E04 Other non-toxic goitre	0.125	0.875	0.000
E55.0 Rickets, active	0.112	0.888	0.000
E61.1 Iron deficiency	0.112	0.888	0.000
E67.8 Other specified hyperalimentation	0.106	0.894	0.000
E67.3 Hypervitaminosis D	0.106	0.894	0.000
E67.2 Megavitamin-B6 syndrome	0.106	0.894	0.000
E67.1 Hypercarotenaemia	0.106	0.894	0.000
E67.0 Hypervitaminosis A	0.106	0.894	0.000
E04.9 Non-toxic goitre, unspecified	0.093	0.907	0.000
E04.8 Other specified non-toxic goitre	0.090	0.910	0.000
E04.0 Non-toxic diffuse goitre	0.087	0.913	0.000
J40-J47 Chronic lower respiratory diseases	0.000	0.922	0.078
J42 Unspecified chronic bronchitis	0.000	0.927	0.073
E55.9 Vitamin D deficiency, unspecified	0.069	0.931	0.000
J46 Status asthmaticus	0.000	0.932	0.068
J45.0 Predominantly allergic asthma	0.000	0.933	0.067
J41 Simple and mucopurulent chronic bronchitis	0.000	0.937	0.063
J41.0 Simple chronic bronchitis	0.000	0.947	0.053
J47 Bronchiectasis	0.000	0.948	0.052
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.000	0.954	0.045
J41.1 Mucopurulent chronic bronchitis	0.000	0.954	0.045
J43 Emphysema	0.000	0.958	0.042
L57.0 Actinic keratosis	0.000	0.965	0.035
J33.0 Polyp of nasal cavity	0.000	0.965	0.035
J43.9 Emphysema, unspecified	0.000	0.968	0.032
Z85.5 Personal history of malignant neoplasm of urinary tract	0.031	0.969	0.000
J43.1 Panlobular emphysema	0.000	0.970	0.030
J43.0 MacLeod's syndrome	0.000	0.970	0.030
J33 Nasal polyp	0.000	0.970	0.030
J43.8 Other emphysema	0.000	0.970	0.029
J33.9 Nasal polyp, unspecified	0.000	0.971	0.029
H18.4 Corneal degeneration	0.026	0.974	0.000
J33.8 Other polyp of sinus	0.000	0.974	0.026
E66 Obesity	0.026	0.974	0.000
H18 Other disorders of cornea	0.026	0.974	0.000
H18.5 Hereditary corneal dystrophies	0.026	0.974	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.025	0.975	0.000
E20-E35 Disorders of other endocrine glands	0.025	0.975	0.000
O48 Prolonged pregnancy	0.000	0.975	0.025
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.025	0.975	0.000
H18.1 Bullous keratopathy	0.025	0.975	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.023	0.977	0.000
H18.9 Disorder of cornea, unspecified	0.022	0.978	0.000
Z03.5 Observation for other suspected cardiovascular diseases	0.022	0.978	0.000
J33.1 Polypoid sinus degeneration	0.000	0.979	0.021
E34 Other endocrine disorders	0.020	0.980	0.000
H18.0 Corneal pigmentations and deposits	0.019	0.981	0.000
E22 Hyperfunction of pituitary gland	0.019	0.981	0.000
E66.1 Drug-induced obesity	0.019	0.981	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.000	0.981	0.019
H18.2 Other corneal oedema	0.019	0.981	0.000
H18.7 Other corneal deformities	0.019	0.981	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.018	0.982	0.000
E32 Diseases of thymus	0.018	0.982	0.000
E30 Disorders of puberty, not elsewhere classified	0.018	0.982	0.000
E31 Polyglandular dysfunction	0.018	0.982	0.000
E25 Adrenogenital disorders	0.018	0.982	0.000
H18.3 Changes in corneal membranes	0.018	0.982	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.000	0.982	0.018
H18.8 Other specified disorders of cornea	0.017	0.982	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.017	0.982	0.000
E27 Other disorders of adrenal gland	0.017	0.983	0.000
E04.2 Non-toxic multinodular goitre	0.017	0.983	0.000
E66.0 Obesity due to excess calories	0.017	0.983	0.000
E26 Hyperaldosteronism	0.016	0.983	0.000
E27.1 Primary adrenocortical insufficiency	0.016	0.984	0.000
E34.9 Endocrine disorder, unspecified	0.016	0.984	0.000
E22.0 Acromegaly and pituitary gigantism	0.016	0.984	0.000
D51 Vitamin B12 deficiency anaemia	0.016	0.984	0.000
E20 Hypoparathyroidism	0.015	0.985	0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.000	0.985	0.015
E34.8 Other specified endocrine disorders	0.015	0.985	0.000
E34.3 Short stature, not elsewhere classified	0.015	0.985	0.000
E34.5 Androgen resistance syndrome	0.014	0.986	0.000
E34.4 Constitutional tall stature	0.014	0.986	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.014	0.986	0.000
E34.1 Other hypersecretion of intestinal hormones	0.014	0.986	0.000
H18.6 Keratoconus	0.014	0.986	0.000
E04.1 Non-toxic single thyroid nodule	0.014	0.986	0.000
E27.2 Addisonian crisis	0.014	0.986	0.000
L57.5 Actinic granuloma	0.000	0.986	0.014
E22.9 Hyperfunction of pituitary gland, unspecified	0.014	0.986	0.000
E22.8 Other hyperfunction of pituitary gland	0.014	0.986	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.014	0.986	0.000
L57.3 Poikiloderma of Civatte	0.000	0.986	0.014
L57.2 Cutis rhomboidalis nuchae	0.000	0.986	0.014
L57.1 Actinic reticuloid	0.000	0.986	0.014
L57.4 Cutis laxa senilis	0.000	0.986	0.014
E29 Testicular dysfunction	0.013	0.987	0.000
E22.1 Hyperprolactinaemia	0.013	0.987	0.000
E34.0 Carcinoid syndrome	0.013	0.987	0.000
E30.9 Disorder of puberty, unspecified	0.013	0.987	0.000
E30.8 Other disorders of puberty	0.013	0.987	0.000
E30.1 Precocious puberty	0.013	0.987	0.000
E30.0 Delayed puberty	0.013	0.987	0.000
E31.9 Polyglandular dysfunction, unspecified	0.013	0.987	0.000
E31.8 Other polyglandular dysfunction	0.013	0.987	0.000
E31.1 Polyglandular hyperfunction	0.013	0.987	0.000
E32.9 Disease of thymus, unspecified	0.013	0.987	0.000
E32.8 Other diseases of thymus	0.013	0.987	0.000
E32.1 Abscess of thymus	0.013	0.987	0.000
E32.0 Persistent hyperplasia of thymus	0.013	0.987	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.013	0.987	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.013	0.987	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.013	0.987	0.000
E25.9 Adrenogenital disorder, unspecified	0.013	0.987	0.000
E25.8 Other adrenogenital disorders	0.013	0.987	0.000
E31.0 Autoimmune polyglandular failure	0.013	0.987	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.013	0.987	0.000
J43.2 Centrilobular emphysema	0.001	0.987	0.012
E14.9 Without complications	0.013	0.987	0.000
E24 Cushing's syndrome	0.013	0.987	0.000
E27.5 Adrenomedullary hyperfunction	0.013	0.987	0.000
E27.0 Other adrenocortical overactivity	0.013	0.987	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.013	0.987	0.000
J44 Other chronic obstructive pulmonary disease	0.000	0.987	0.013
E26.9 Hyperaldosteronism, unspecified	0.012	0.987	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.013	0.987	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.000	0.988	0.012
E27.3 Drug-induced adrenocortical insufficiency	0.012	0.988	0.000
E26.8 Other hyperaldosteronism	0.012	0.988	0.000
E26.1 Secondary hyperaldosteronism	0.012	0.988	0.000
D51.2 Transcobalamin II deficiency	0.012	0.988	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.012	0.988	0.000
E11.9 Without complications	0.011	0.989	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.011	0.989	0.000
E27.9 Disorder of adrenal gland, unspecified	0.011	0.989	0.000
J40 Bronchitis, not specified as acute or chronic	0.000	0.989	0.011
E20.8 Other hypoparathyroidism	0.011	0.989	0.000
E20.1 Pseudohypoparathyroidism	0.011	0.989	0.000
E20.0 Idiopathic hypoparathyroidism	0.011	0.989	0.000
E28 Ovarian dysfunction	0.011	0.989	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.990	0.010
M54.4 Lumbago with sciatica	0.010	0.990	0.000
E27.8 Other specified disorders of adrenal gland	0.010	0.990	0.000
E29.9 Testicular dysfunction, unspecified	0.010	0.990	0.000
E29.8 Other testicular dysfunction	0.010	0.990	0.000
E29.0 Testicular hyperfunction	0.010	0.990	0.000
E26.0 Primary hyperaldosteronism	0.010	0.990	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.990	0.010
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.009	0.991	0.000
E24.3 Ectopic ACTH syndrome	0.009	0.991	0.000
E24.2 Drug-induced Cushing's syndrome	0.009	0.991	0.000
E24.1 Nelson's syndrome	0.009	0.991	0.000
E24.8 Other Cushing's syndrome	0.009	0.991	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.009	0.991	0.000
E23 Hypofunction and other disorders of pituitary gland	0.008	0.991	0.000
E28.9 Ovarian dysfunction, unspecified	0.008	0.992	0.000
E28.8 Other ovarian dysfunction	0.008	0.992	0.000
E28.1 Androgen excess	0.008	0.992	0.000
E28.0 Oestrogen excess	0.008	0.992	0.000
M24.1 Other articular cartilage disorders	0.000	0.992	0.008
E20.9 Hypoparathyroidism, unspecified	0.008	0.992	0.000
E24.9 Cushing's syndrome, unspecified	0.008	0.992	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.000	0.992	0.008
M54.47 Lumbago with sciatica (Lumbosacral region)	0.008	0.992	0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.007	0.993	0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.007	0.993	0.000
M54.44 Lumbago with sciatica-Thoracic	0.007	0.993	0.000
M54.43 Lumbago with sciatica-Cervicothoracic	0.007	0.993	0.000
M54.42 Lumbago with sciatica-Cervical	0.007	0.993	0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.007	0.993	0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.007	0.993	0.000
Z53.9 Procedure not carried out, unspecified reason	0.000	0.993	0.007
E24.0 Pituitary-dependent Cushing's disease	0.007	0.993	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.993	0.007
F60 Specific personality disorders	0.007	0.993	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.007	0.993	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.993	0.007
E28.3 Primary ovarian failure	0.007	0.993	0.000
R41.0 Disorientation, unspecified	0.007	0.993	0.000
F60.3 Emotionally unstable personality disorder	0.007	0.993	0.000
E21.4 Other specified disorders of parathyroid gland	0.007	0.993	0.000
E23.7 Disorder of pituitary gland, unspecified	0.006	0.993	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.993	0.007
M54.49 Lumbago with sciatica (Site unspecified)	0.007	0.993	0.000
F60.8 Other specific personality disorders	0.007	0.993	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.006	0.994	0.000
E23.1 Drug-induced hypopituitarism	0.006	0.994	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.006	0.994	0.000
Z39.0 Care and examination immediately after delivery	0.000	0.994	0.006
F60.5 Anankastic personality disorder	0.006	0.994	0.000
F60.0 Paranoid personality disorder	0.006	0.994	0.000
E23.2 Diabetes insipidus	0.006	0.994	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.000	0.994	0.006
M24.18 Other articular cartilage disorders (Other)	0.000	0.994	0.006
M24.12 Other articular cartilage disorders (Upper arm)	0.000	0.994	0.006
M24.10 Other articular cartilage disorders (Multiple sites)	0.000	0.994	0.006
E21.5 Disorder of parathyroid gland, unspecified	0.006	0.994	0.000
E21.2 Other hyperparathyroidism	0.006	0.994	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.000	0.994	0.006
C49.5 Connective and soft tissue of pelvis	0.006	0.994	0.000
F60.6 Anxious [avoidant] personality disorder	0.006	0.994	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.006	0.994	0.000
F60.9 Personality disorder, unspecified	0.006	0.994	0.000
M24.14 Other articular cartilage disorders (Hand)	0.000	0.994	0.006
C49.9 Connective and soft tissue, unspecified	0.006	0.994	0.000
F60.4 Histrionic personality disorder	0.005	0.995	0.000
F60.1 Schizoid personality disorder	0.005	0.995	0.000
F60-F69 Disorders of adult personality and behaviour	0.005	0.995	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.995	0.005
F60.2 Dissocial personality disorder	0.005	0.995	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.005	0.995	0.000
C49.0 Connective and soft tissue of head, face and neck	0.005	0.995	0.000
E21.0 Primary hyperparathyroidism	0.005	0.995	0.000
C49.3 Connective and soft tissue of thorax	0.005	0.995	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.000	0.995	0.005
E29.1 Testicular hypofunction	0.005	0.995	0.000
F64 Gender identity disorders	0.005	0.995	0.000
C49.6 Connective and soft tissue of trunk, unspecified	0.005	0.995	0.000
F69 Unspecified disorder of adult personality and behaviour	0.005	0.995	0.000
F64.0 Transsexualism	0.005	0.995	0.000
J38.3 Other diseases of vocal cords	0.000	0.995	0.005
F60.7 Dependent personality disorder	0.005	0.995	0.000
D50-D53 Nutritional anaemias	0.005	0.995	0.000
L58 Radiodermatitis	0.000	0.995	0.004
L55 Sunburn	0.000	0.995	0.004
C49.4 Connective and soft tissue of abdomen	0.005	0.995	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.005	0.995	0.000
C49.8 Overlapping lesion of connective and soft tissue	0.004	0.996	0.000
C43 Malignant melanoma of skin	0.000	0.996	0.004
C49.1 Connective and soft tissue of upper limb, including shoulder	0.004	0.996	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.004	0.996	0.000
E23.6 Other disorders of pituitary gland	0.004	0.996	0.000
L56 Other acute skin changes due to ultraviolet radiation	0.000	0.996	0.004
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.004	0.996	0.000
F65 Disorders of sexual preference	0.004	0.996	0.000
F63 Habit and impulse disorders	0.004	0.996	0.000
N48.4 Impotence of organic origin	0.004	0.996	0.000
O63.1 Prolonged second stage (of labour)	0.000	0.996	0.004
F68 Other disorders of adult personality and behaviour	0.004	0.996	0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.000	0.996	0.004
E21.3 Hyperparathyroidism, unspecified	0.004	0.996	0.000
F61 Mixed and other personality disorders	0.004	0.996	0.000
E28.2 Polycystic ovarian syndrome	0.004	0.996	0.000
Z37.0 Single live birth	0.000	0.996	0.004
D52 Folate deficiency anaemia	0.004	0.996	0.000
K76.9 Liver disease, unspecified	0.000	0.996	0.004
D53 Other nutritional anaemias	0.004	0.996	0.000
F64.9 Gender identity disorder, unspecified	0.004	0.996	0.000
F64.8 Other gender identity disorders	0.004	0.996	0.000
F64.2 Gender identity disorder of childhood	0.004	0.996	0.000
F64.1 Dual-role transvestism	0.004	0.996	0.000
M19.27 Other secondary arthrosis (Ankle and foot)	0.004	0.996	0.000
F62.9 Enduring personality change, unspecified	0.004	0.996	0.000
I45.9 Conduction disorder, unspecified	0.000	0.996	0.004
L55.9 Sunburn, unspecified	0.000	0.996	0.003
L55.8 Other sunburn	0.000	0.996	0.003
L55.2 Sunburn of third degree	0.000	0.996	0.003
L55.1 Sunburn of second degree	0.000	0.996	0.003
L55.0 Sunburn of first degree	0.000	0.996	0.003
L58.9 Radiodermatitis, unspecified	0.000	0.996	0.003
L58.1 Chronic radiodermatitis	0.000	0.996	0.003
L58.0 Acute radiodermatitis	0.000	0.996	0.003
S81.8 Open wound of other parts of lower leg	0.004	0.996	0.000
C43.8 Overlapping malignant melanoma of skin	0.000	0.997	0.003
C43.0 Malignant melanoma of lip	0.000	0.997	0.003
M25.96 Joint disorder, unspecified (Lower leg)	0.003	0.997	0.000
F62.8 Other enduring personality changes	0.003	0.997	0.000
F62.1 Enduring personality change after psychiatric illness	0.003	0.997	0.000
F62.0 Enduring personality change after catastrophic experience	0.003	0.997	0.000
D52.9 Folate deficiency anaemia, unspecified	0.003	0.997	0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.000	0.997	0.003
C49.2 Connective and soft tissue of lower limb, including hip	0.003	0.997	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.000	0.997	0.003
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.997	0.003
L56.4 Polymorphous light eruption	0.000	0.997	0.003
D61.9 Aplastic anaemia, unspecified	0.003	0.997	0.000
L56.3 Solar urticaria	0.000	0.997	0.003
L56.2 Photocontact dermatitis [berloque dermatitis]	0.000	0.997	0.003
L56.1 Drug photoallergic response	0.000	0.997	0.003
L56.0 Drug phototoxic response	0.000	0.997	0.003
Z36.0 Antenatal screening for chromosomal anomalies	0.003	0.997	0.000
L56.9 Acute skin change due to ultraviolet radiation, unspecified	0.000	0.997	0.003
D53.9 Nutritional anaemia, unspecified	0.003	0.997	0.000
F63.9 Habit and impulse disorder, unspecified	0.003	0.997	0.000
F63.8 Other habit and impulse disorders	0.003	0.997	0.000
F63.3 Trichotillomania	0.003	0.997	0.000
F63.2 Pathological stealing [kleptomania]	0.003	0.997	0.000
F63.1 Pathological fire-setting [pyromania]	0.003	0.997	0.000
F63.0 Pathological gambling	0.003	0.997	0.000
F65.9 Disorder of sexual preference, unspecified	0.003	0.997	0.000
F65.8 Other disorders of sexual preference	0.003	0.997	0.000
F65.6 Multiple disorders of sexual preference	0.003	0.997	0.000
F65.5 Sadomasochism	0.003	0.997	0.000
F65.4 Paedophilia	0.003	0.997	0.000
F65.3 Voyeurism	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations