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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs375984
log Bayes Factor = 101.301
Chromosome 6   position 29,644,502  (GRCh37) Explore rs375984 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
0.999 0.001 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.999 0.001 0.000
E83.1 Disorders of iron metabolism
0.000 0.002 0.998
E10.1 With ketoacidosis
0.996 0.004 0.000
M05-M14 Inflammatory polyarthropathies
0.995 0.005 0.000
M07 Psoriatic and enteropathic arthropathies
0.994 0.006 0.000
M07.3 Other psoriatic arthropathies
0.993 0.007 0.000
M17 Gonarthrosis [arthrosis of knee]
0.992 0.008 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.992 0.008 0.000
M15-M19 Arthrosis
0.992 0.008 0.000
M17.9 Gonarthrosis, unspecified
0.990 0.010 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.989 0.011 0.000
E10.3 With ophthalmic complications
0.988 0.012 0.000
M20-M25 Other joint disorders
0.988 0.012 0.000
N13 Obstructive and reflux uropathy
0.987 0.013 0.000
N00-N08 Glomerular diseases
0.987 0.013 0.000
Chapter XIV Diseases of the genitourinary system
0.986 0.014 0.000
N10-N16 Renal tubulo-interstitial diseases
0.985 0.015 0.000
L40-L45 Papulosquamous disorders
0.984 0.016 0.000
K51 Ulcerative colitis
0.000 0.018 0.982
E16 Other disorders of pancreatic internal secretion
0.982 0.018 0.000
M25 Other joint disorders, not elsewhere classified
0.980 0.020 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.978 0.022 0.000
E16.2 Hypoglycaemia, unspecified
0.977 0.023 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.023 0.977
N08 Glomerular disorders in diseases classified elsewhere
0.975 0.025 0.000
Chapter I Certain infectious and parasitic diseases
0.972 0.028 0.000
M17.1 Other primary gonarthrosis
0.971 0.029 0.000
M86-M90 Other osteopathies
0.970 0.030 0.000
B35-B49 Mycoses
0.969 0.031 0.000
M60-M63 Disorders of muscles
0.968 0.032 0.000
M35 Other systemic involvement of connective tissue
0.967 0.033 0.000
B37 Candidiasis
0.967 0.033 0.000
M35.0 Sicca syndrome [Sjogren]
0.962 0.038 0.000
K51.2 Ulcerative (chronic) proctitis
0.000 0.038 0.962
M07.30 Other psoriatic arthropathies (Multiple sites)
0.961 0.039 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.959 0.041 0.000
N04 Nephrotic syndrome
0.957 0.043 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.956 0.044 0.000
E10.2 With renal complications
0.954 0.046 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.952 0.048 0.000
K51.4 Pseudopolyposis of colon
0.000 0.048 0.952
M25.5 Pain in joint
0.951 0.049 0.000
E10.4 With neurological complications
0.950 0.050 0.000
B37.8 Candidiasis of other sites
0.946 0.054 0.000
M62 Other disorders of muscle
0.941 0.059 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.941 0.059 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.938 0.062 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.935 0.065 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.935 0.065 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.933 0.067 0.000
D80-D89 Certain disorders involving the immune mechanism
0.932 0.068 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.932 0.068 0.000
E14 Unspecified diabetes mellitus
0.929 0.071 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.924 0.076 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.920 0.080 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.918 0.082 0.000
K50-K52 Noninfective enteritis and colitis
0.026 0.082 0.892
M62.8 Other specified disorders of muscle
0.914 0.086 0.000
N04.9 Unspecified
0.911 0.089 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.906 0.094 0.000
B02 Zoster [herpes zoster]
0.906 0.094 0.000
M89 Other disorders of bone
0.906 0.094 0.000
B37.9 Candidiasis, unspecified
0.904 0.096 0.000
B37.0 Candidal stomatitis
0.900 0.100 0.000
M25.56 Pain in joint (Lower leg)
0.899 0.101 0.000
E07 Other disorders of thyroid
0.897 0.103 0.000
M86 Osteomyelitis
0.891 0.109 0.000
K50 Crohn's disease [regional enteritis]
0.001 0.111 0.888
E20-E35 Disorders of other endocrine glands
0.886 0.114 0.000
M25.4 Effusion of joint
0.886 0.114 0.000
N11 Chronic tubulo-interstitial nephritis
0.885 0.115 0.000
K50.9 Crohn's disease, unspecified
0.000 0.115 0.885
N05 Unspecified nephritic syndrome
0.885 0.115 0.000
E11 Non-insulin-dependent diabetes mellitus
0.883 0.117 0.000
D86 Sarcoidosis
0.883 0.117 0.000
M25.54 Pain in joint (Hand)
0.881 0.119 0.000
M35.7 Hypermobility syndrome
0.877 0.123 0.000
L40.0 Psoriasis vulgaris
0.876 0.124 0.000
B02.9 Zoster without complication
0.871 0.129 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.871 0.129 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.862 0.138 0.000
N13.6 Pyonephrosis
0.857 0.143 0.000
K51.8 Other ulcerative colitis
0.000 0.144 0.856
Q76 Congenital malformations of spine and bony thorax
0.856 0.144 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.145 0.855
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.853 0.147 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.850 0.150 0.000
D60-D64 Aplastic and other anaemias
0.850 0.150 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.846 0.154 0.000
B00 Herpesviral [herpes simplex] infections
0.846 0.154 0.000
D55-D59 Haemolytic anaemias
0.844 0.156 0.000
M91-M94 Chondropathies
0.842 0.158 0.000
D86.9 Sarcoidosis, unspecified
0.842 0.158 0.000
E14.3 With ophthalmic complications
0.842 0.158 0.000
M25.57 Pain in joint (Ankle and foot)
0.834 0.166 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.831 0.169 0.000
M17.5 Other secondary gonarthrosis
0.830 0.170 0.000
M10 Gout
0.830 0.170 0.000
E14.5 With peripheral circulatory complications
0.829 0.171 0.000
Q00-Q07 Congenital malformations of the nervous system
0.826 0.174 0.000
M11 Other crystal arthropathies
0.825 0.175 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.824 0.176 0.000
Chapter VI Diseases of the nervous system
0.823 0.177 0.000
N02 Recurrent and persistent haematuria
0.822 0.178 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.812 0.188 0.000
M25.9 Joint disorder, unspecified
0.812 0.188 0.000
N04.2 Diffuse membranous glomerulonephritis
0.811 0.189 0.000
M21 Other acquired deformities of limbs
0.810 0.190 0.000
L40.1 Generalised pustular psoriasis
0.810 0.190 0.000
E11.2 With renal complications
0.809 0.191 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.808 0.192 0.000
M32 Systemic lupus erythematosus
0.807 0.193 0.000
Q65 Congenital deformities of hip
0.804 0.196 0.000
A15-A19 Tuberculosis
0.803 0.197 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.800 0.200 0.000
E07.8 Other specified disorders of thyroid
0.800 0.200 0.000
G30-G32 Other degenerative diseases of the nervous system
0.799 0.201 0.000
E11.6 With other specified complications
0.796 0.204 0.000
M25.47 Effusion of joint (Ankle and foot)
0.796 0.204 0.000
E05.8 Other thyrotoxicosis
0.793 0.207 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.787 0.213 0.000
Q40 Other congenital malformations of upper alimentary tract
0.779 0.221 0.000
N05.2 Diffuse membranous glomerulonephritis
0.779 0.221 0.000
G35 Multiple sclerosis
0.779 0.221 0.000
M89.5 Osteolysis
0.777 0.222 0.000
A20-A28 Certain zoonotic bacterial diseases
0.775 0.225 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.775 0.225 0.000
E50-E64 Other nutritional deficiencies
0.775 0.225 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.772 0.228 0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified
0.772 0.228 0.000
E40-E46 Malnutrition
0.769 0.231 0.000
M25.46 Effusion of joint (Lower leg)
0.766 0.234 0.000
E24 Cushing's syndrome
0.765 0.235 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.765 0.235 0.000
M07.38 Other psoriatic arthropathies (Other)
0.763 0.237 0.000
M21.0 Valgus deformity, not elsewhere classified
0.763 0.237 0.000
M93 Other osteochondropathies
0.762 0.238 0.000
K50.1 Crohn's disease of large intestine
0.000 0.239 0.761
E11.5 With peripheral circulatory complications
0.761 0.239 0.000
M25.53 Pain in joint (Forearm)
0.760 0.240 0.000
M65-M68 Disorders of synovium and tendon
0.760 0.240 0.000
M86.6 Other chronic osteomyelitis
0.758 0.242 0.000
E10.0 With coma
0.758 0.242 0.000
G37 Other demyelinating diseases of central nervous system
0.758 0.242 0.000
M10.0 Idiopathic gout
0.757 0.243 0.000
M86.9 Osteomyelitis, unspecified
0.755 0.245 0.000
M62.88 Other specified disorders of muscle (Other)
0.755 0.245 0.000
M25.58 Pain in joint (Other)
0.755 0.245 0.000
E13 Other specified diabetes mellitus
0.755 0.245 0.000
B00.5 Herpesviral ocular disease
0.754 0.246 0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)
0.754 0.246 0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis
0.753 0.247 0.000
M00-M03 Infectious arthropathies
0.751 0.249 0.000
D61 Other aplastic anaemias
0.750 0.250 0.000
E20 Hypoparathyroidism
0.749 0.250 0.000
M12 Other specific arthropathies
0.749 0.251 0.000
E10.7 With multiple complications
0.749 0.251 0.000
E10.6 With other specified complications
0.748 0.251 0.000
N25-N29 Other disorders of kidney and ureter
0.748 0.252 0.000
M89.3 Hypertrophy of bone
0.747 0.253 0.000
E11.1 With ketoacidosis
0.746 0.254 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.746 0.254 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.746 0.254 0.000
M14 Arthropathies in other diseases classified elsewhere
0.745 0.255 0.000
E10.8 With unspecified complications
0.745 0.255 0.000
G31.8 Other specified degenerative diseases of nervous system
0.743 0.257 0.000
M89.0 Algoneurodystrophy
0.743 0.257 0.000
M89.9 Disorder of bone, unspecified
0.741 0.259 0.000
Q78 Other osteochondrodysplasias
0.738 0.262 0.000
N02.9 Unspecified
0.737 0.263 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.264 0.736
B02.2 Zoster with other nervous system involvement
0.736 0.264 0.000
L40.4 Guttate psoriasis
0.735 0.265 0.000
L40.3 Pustulosis palmaris et plantaris
0.734 0.266 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.734 0.266 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.733 0.266 0.000
G70-G73 Diseases of myoneural junction and muscle
0.732 0.268 0.000
E27 Other disorders of adrenal gland
0.730 0.270 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.730 0.270 0.000
A65-A69 Other spirochaetal diseases
0.730 0.270 0.000
M07.6 Other enteropathic arthropathies
0.728 0.271 0.000
M25.3 Other instability of joint
0.728 0.272 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.272 0.728
D83 Common variable immunodeficiency
0.727 0.273 0.000
E23 Hypofunction and other disorders of pituitary gland
0.727 0.273 0.000
M34 Systemic sclerosis
0.726 0.274 0.000
M60 Myositis
0.725 0.274 0.000
L10-L14 Bullous disorders
0.724 0.276 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.722 0.278 0.000
B37.4 Candidiasis of other urogenital sites
0.722 0.278 0.000
B37.7 Candidal septicaemia
0.721 0.279 0.000
L50-L54 Urticaria and erythema
0.720 0.280 0.000
B49 Unspecified mycosis
0.719 0.281 0.000
N11.1 Chronic obstructive pyelonephritis
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
N04.1 Focal and segmental glomerular lesions
0.717 0.283 0.000
B00.9 Herpesviral infection, unspecified
0.715 0.285 0.000
E11.7 With multiple complications
0.714 0.286 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.714 0.286 0.000
M25.42 Effusion of joint (Upper arm)
0.714 0.286 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.713 0.287 0.000
M08 Juvenile arthritis
0.713 0.287 0.000
E25 Adrenogenital disorders
0.713 0.287 0.000
M07.5 Arthropathy in ulcerative colitis
0.712 0.287 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.712 0.287 0.000
M07.2 Psoriatic spondylitis
0.712 0.287 0.000
M07.1 Arthritis mutilans
0.712 0.287 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.712 0.287 0.000
B65-B83 Helminthiases
0.712 0.287 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.712 0.288 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.712 0.288 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.712 0.288 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.712 0.288 0.000
Q70 Syndactyly
0.712 0.288 0.000
L42 Pityriasis rosea
0.712 0.288 0.000
E27.1 Primary adrenocortical insufficiency
0.711 0.289 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.711 0.289 0.000
Q76.0 Spina bifida occulta
0.710 0.289 0.000
D58 Other hereditary haemolytic anaemias
0.710 0.290 0.000
E15 Nondiabetic hypoglycaemic coma
0.709 0.290 0.000
E16.1 Other hypoglycaemia
0.709 0.291 0.000
E14.2 Withrenal complications
0.709 0.291 0.000
M88 Paget's disease of bone [osteitis deformans]
0.709 0.291 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.707 0.293 0.000
N06 Isolated proteinuria with specified morphological lesion
0.707 0.293 0.000
N01 Rapidly progressive nephritic syndrome
0.707 0.293 0.000
N00 Acute nephritic syndrome
0.707 0.293 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.707 0.293 0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.707 0.293 0.000
N05.1 Focal and segmental glomerular lesions
0.706 0.294 0.000
Q35-Q37 Cleft lip and cleft palate
0.706 0.294 0.000
L44 Other papulosquamous disorders
0.706 0.294 0.000
L41 Parapsoriasis
0.706 0.294 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.706 0.294 0.000
E07.9 Disorder of thyroid, unspecified
0.706 0.294 0.000
Q65.8 Other congenital deformities of hip
0.705 0.295 0.000
N04.0 Minor glomerular abnormality
0.705 0.295 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.704 0.296 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.704 0.296 0.000
E16.4 Abnormal secretion of gastrin
0.704 0.296 0.000
E16.3 Increased secretion of glucagon
0.704 0.296 0.000
M11.2 Other chondrocalcinosis
0.704 0.296 0.000
B37.2 Candidiasis of skin and nail
0.703 0.297 0.000
M25.52 Pain in joint (Upper arm)
0.703 0.297 0.000
D64 Other anaemias
0.703 0.297 0.000
M25.2 Flail joint
0.702 0.297 0.000
M25.1 Fistula of joint
0.702 0.297 0.000
N15 Other renal tubulo-interstitial diseases
0.702 0.298 0.000
M70-M79 Other soft tissue disorders
0.702 0.298 0.000
D50-D53 Nutritional anaemias
0.702 0.298 0.000
M62.0 Diastasis of muscle
0.699 0.301 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.699 0.301 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.699 0.301 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.699 0.301 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.699 0.301 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.699 0.301 0.000
Q66 Congenital deformities of feet
0.698 0.302 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.697 0.303 0.000
A75-A79 Rickettsioses
0.697 0.303 0.000
A70-A74 Other diseases caused by chlamydiae
0.697 0.303 0.000
B36 Other superficial mycoses
0.696 0.304 0.000
B48 Other mycoses, not elsewhere classified
0.695 0.305 0.000
B47 Mycetoma
0.695 0.305 0.000
B46 Zygomycosis
0.695 0.305 0.000
B45 Cryptococcosis
0.695 0.305 0.000
B43 Chromomycosis and phaeomycotic abscess
0.695 0.305 0.000
B42 Sporotrichosis
0.695 0.305 0.000
B41 Paracoccidioidomycosis
0.695 0.305 0.000
B40 Blastomycosis
0.695 0.305 0.000
B39 Histoplasmosis
0.695 0.305 0.000
B38 Coccidioidomycosis
0.695 0.305 0.000
E21.3 Hyperparathyroidism, unspecified
0.694 0.306 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.694 0.306 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.694 0.306 0.000
M61 Calcification and ossification of muscle
0.694 0.306 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.693 0.306 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.693 0.306 0.000
M35.5 Multifocal fibrosclerosis
0.693 0.306 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.693 0.306 0.000
B37.6 Candidal endocarditis
0.693 0.307 0.000
B37.5 Candidal meningitis
0.693 0.307 0.000
M33 Dermatopolymyositis
0.693 0.307 0.000
M18 Arthrosis of first carpometacarpal joint
0.692 0.308 0.000
E14.1 With ketoacidosis
0.692 0.308 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.691 0.309 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.690 0.310 0.000
Q74 Other congenital malformations of limb(s)
0.690 0.310 0.000
B44 Aspergillosis
0.690 0.310 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.688 0.312 0.000
M86.8 Other osteomyelitis
0.688 0.312 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.687 0.313 0.000
B01 Varicella [chickenpox]
0.687 0.313 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.313 0.686
N04.8 Other
0.686 0.313 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.686 0.313 0.000
N04.6 Dense deposit disease
0.686 0.313 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.686 0.313 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.686 0.313 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.686 0.313 0.000
M89.55 Osteolysis (Pelvic region and thigh)
0.686 0.314 0.000
N02.2 Diffuse membranous glomerulonephritis
0.685 0.315 0.000
M31 Other necrotising vasculopathies
0.685 0.315 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.685 0.315 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.685 0.315 0.000
M90 Osteopathies in diseases classified elsewhere
0.684 0.316 0.000
D73 Diseases of spleen
0.683 0.317 0.000
D86.8 Sarcoidosis of other and combined sites
0.683 0.317 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.683 0.317 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.682 0.318 0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically
0.681 0.319 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.681 0.319 0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances
0.680 0.320 0.000
D80 Immunodeficiency with predominantly antibody defects
0.680 0.320 0.000
M25.43 Effusion of joint (Forearm)
0.679 0.321 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.679 0.321 0.000
E14.8 With unspecified complications
0.679 0.321 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.678 0.322 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.677 0.323 0.000
E06 Thyroiditis
0.677 0.323 0.000
B35 Dermatophytosis
0.676 0.324 0.000
M62.9 Disorder of muscle, unspecified
0.675 0.325 0.000
M62.4 Contracture of muscle
0.675 0.325 0.000
M62.3 Immobility syndrome (paraplegic)
0.675 0.325 0.000
M62.2 Ischaemic infarction of muscle
0.675 0.325 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.675 0.325 0.000
Q75 Other congenital malformations of skull and face bones
0.675 0.325 0.000
Q73 Reduction defects of unspecified limb
0.675 0.325 0.000
Q72 Reduction defects of lower limb
0.675 0.325 0.000
Q71 Reduction defects of upper limb
0.675 0.325 0.000
Q69 Polydactyly
0.675 0.325 0.000
Q68 Other congenital musculoskeletal deformities
0.675 0.325 0.000
N25 Disorders resulting from impaired renal tubular function
0.674 0.326 0.000
Q40.2 Other specified congenital malformations of stomach
0.674 0.326 0.000
M21.8 Other specified acquired deformities of limbs
0.674 0.326 0.000
Q45 Other congenital malformations of digestive system
0.673 0.327 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.673 0.327 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.673 0.327 0.000
M62.6 Muscle strain
0.672 0.327 0.000
B02.3 Zoster ocular disease
0.672 0.328 0.000
K51.5 Mucosal proctocolitis
0.000 0.328 0.672
M25.59 Pain in joint (Site unspecified)
0.672 0.328 0.000
B06 Rubella [German measles]
0.671 0.329 0.000
B05 Measles
0.671 0.329 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.671 0.329 0.000
B04 Monkeypox
0.671 0.329 0.000
B03 Smallpox
0.671 0.329 0.000
M62.83 Other specified disorders of muscle (Forearm)
0.669 0.331 0.000
D81 Combined immunodeficiencies
0.668 0.332 0.000
Q60-Q64 Congenital malformations of the urinary system
0.667 0.333 0.000
M93.9 Osteochondropathy, unspecified
0.667 0.333 0.000
D68 Other coagulation defects
0.667 0.333 0.000
E14.7 With multiple complications
0.666 0.334 0.000
E14.0 With coma
0.666 0.334 0.000
E14.6 With other specified complications
0.666 0.334 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.666 0.334 0.000
K90 Intestinal malabsorption
0.664 0.336 0.000
M15 Polyarthrosis
0.664 0.336 0.000
Q03 Congenital hydrocephalus
0.664 0.336 0.000
G31.0 Circumscribed brain atrophy
0.664 0.336 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.662 0.338 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.659 0.341 0.000
B37.3 Candidiasis of vulva and vagina
0.657 0.343 0.000
D62 Acute posthaemorrhagic anaemia
0.657 0.343 0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.656 0.344 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.656 0.344 0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)
0.655 0.345 0.000
M62.87 Other specified disorders of muscle (Ankle and foot)
0.655 0.345 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.655 0.345 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.655 0.345 0.000
Q40.1 Congenital hiatus hernia
0.654 0.346 0.000
M25.51 Pain in joint (Shoulder region)
0.654 0.346 0.000
E11.0 With coma
0.654 0.346 0.000
M87 Osteonecrosis
0.654 0.346 0.000
D59 Acquired haemolytic anaemia
0.653 0.347 0.000
B25-B34 Other viral diseases
0.653 0.347 0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)
0.652 0.348 0.000
E20.9 Hypoparathyroidism, unspecified
0.652 0.348 0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)
0.650 0.350 0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)
0.650 0.350 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.650 0.350 0.000
B02.8 Zoster with other complications
0.650 0.350 0.000
B02.7 Disseminated zoster
0.650 0.350 0.000
B02.1 Zoster meningitis
0.650 0.350 0.000
B02.0 Zoster encephalitis
0.650 0.350 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.649 0.350 0.000
M89.6 Osteopathy after poliomyelitis
0.649 0.351 0.000
M89.2 Other disorders of bone development and growth
0.649 0.351 0.000
M89.1 Epiphyseal arrest
0.649 0.351 0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis
0.649 0.351 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.648 0.351 0.000
E29 Testicular dysfunction
0.648 0.352 0.000
G70 Myasthenia gravis and other myoneural disorders
0.646 0.354 0.000
Q05 Spina bifida
0.646 0.354 0.000
M62.81 Other specified disorders of muscle (Shoulder region)
0.646 0.354 0.000
D66 Hereditary factor VIII deficiency
0.645 0.355 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.645 0.355 0.000
M25.7 Osteophyte
0.645 0.355 0.000
D82 Immunodeficiency associated with other major defects
0.644 0.355 0.000
E07.1 Dyshormogenetic goitre
0.643 0.357 0.000
E07.0 Hypersecretion of calcitonin
0.643 0.357 0.000
D86.0 Sarcoidosis of lung
0.643 0.357 0.000
D84 Other immunodeficiencies
0.642 0.358 0.000
M25.0 Haemarthrosis
0.642 0.358 0.000
M25.99 Joint disorder, unspecified (Site unspecified)
0.641 0.359 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.640 0.360 0.000
D72 Other disorders of white blood cells
0.640 0.360 0.000
D61.9 Aplastic anaemia, unspecified
0.639 0.361 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.638 0.361 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.638 0.361 0.000
M86.3 Chronic multifocal osteomyelitis
0.638 0.361 0.000
M86.2 Subacute osteomyelitis
0.638 0.361 0.000
M86.1 Other acute osteomyelitis
0.638 0.361 0.000
M86.0 Acute haematogenous osteomyelitis
0.638 0.361 0.000
N05.8 Other
0.637 0.363 0.000
B00.8 Other forms of herpesviral infection
0.635 0.365 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.635 0.365 0.000
E32 Diseases of thymus
0.635 0.365 0.000
E31 Polyglandular dysfunction
0.635 0.365 0.000
E30 Disorders of puberty, not elsewhere classified
0.635 0.365 0.000
M25.49 Effusion of joint (Site unspecified)
0.635 0.365 0.000
M25.48 Effusion of joint (Other)
0.635 0.365 0.000
N11.8 Other chronic tubulo-interstitial nephritis
0.635 0.365 0.000
D69 Purpura and other haemorrhagic conditions
0.635 0.365 0.000
N05.7 Diffuse crescentic glomerulonephritis
0.634 0.366 0.000
N05.6 Dense deposit disease
0.634 0.366 0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.634 0.366 0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.634 0.366 0.000
N05.0 Minor glomerular abnormality
0.634 0.366 0.000
A28 Other zoonotic bacterial diseases, not elsewhere classified
0.633 0.367 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.633 0.367 0.000
M93.1 Kienbock's disease of adults
0.633 0.367 0.000
M25.76 Osteophyte (Lower leg)
0.632 0.368 0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)
0.631 0.368 0.000
M72 Fibroblastic disorders
0.630 0.370 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.628 0.372 0.000
E24.0 Pituitary-dependent Cushing's disease
0.628 0.372 0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)
0.627 0.373 0.000
M67 Other disorders of synovium and tendon
0.627 0.373 0.000
E11.8 With unspecified complications
0.626 0.374 0.000
E24.2 Drug-induced Cushing's syndrome
0.626 0.374 0.000
Q79.6 Ehlers-Danlos syndrome
0.626 0.374 0.000
Q04 Other congenital malformations of brain
0.625 0.374 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.624 0.376 0.000
M25.36 Other instability of joint (Lower leg)
0.623 0.377 0.000
K50.8 Other Crohn's disease
0.001 0.378 0.622
E55 Vitamin D deficiency
0.622 0.378 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.618 0.382 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.618 0.382 0.000
D86.3 Sarcoidosis of skin
0.617 0.383 0.000
D64.9 Anaemia, unspecified
0.617 0.383 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.617 0.383 0.000
M10.02 Idiopathic gout (Upper arm)
0.617 0.383 0.000
Q07 Other congenital malformations of nervous system
0.617 0.383 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.616 0.384 0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)
0.616 0.384 0.000
Q76.1 Klippel-Feil syndrome
0.616 0.384 0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)
0.615 0.385 0.000
M66 Spontaneous rupture of synovium and tendon
0.614 0.386 0.000
E51 Thiamine deficiency
0.614 0.386 0.000
Q76.9 Congenital malformation of bony thorax, unspecified
0.614 0.386 0.000
Q76.8 Other congenital malformations of bony thorax
0.614 0.386 0.000
Q76.7 Congenital malformation of sternum
0.614 0.386 0.000
Q76.6 Other congenital malformations of ribs
0.614 0.386 0.000
Q76.5 Cervical rib
0.614 0.386 0.000
Q76.3 Congenital scoliosis due to congenital bony malformation
0.614 0.386 0.000
Q76.2 Congenital spondylolisthesis
0.614 0.386 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.612 0.388 0.000
B50-B64 Protozoal diseases
0.612 0.388 0.000
E61 Deficiency of other nutrient elements
0.611 0.389 0.000
B00.1 Herpesviral vesicular dermatitis
0.611 0.389 0.000
L40.8 Other psoriasis
0.610 0.390 0.000
E10.5 With peripheral circulatory complications
0.610 0.390 0.000
N26 Unspecified contracted kidney
0.610 0.390 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.609 0.391 0.000
M10.00 Idiopathic gout (Multiple sites)
0.609 0.391 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.609 0.391 0.000
D61.0 Constitutional aplastic anaemia
0.608 0.392 0.000
M62.84 Other specified disorders of muscle (Hand)
0.607 0.393 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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