TreeWAS – Variant ID: rs3763305

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
J33.9 Nasal polyp, unspecified	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
M35.3 Polymyalgia rheumatica	1.000	0.000	0.000
J33 Nasal polyp	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
Chapter VIII Diseases of the ear and mastoid process	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
M35 Other systemic involvement of connective tissue	1.000	0.000	0.000
J30-J39 Other diseases of upper respiratory tract	1.000	0.000	0.000
J33.0 Polyp of nasal cavity	1.000	0.000	0.000
M31 Other necrotising vasculopathies	0.999	0.001	0.000
H65-H75 Diseases of middle ear and mastoid	0.999	0.001	0.000
K90.0 Coeliac disease	0.000	0.001	0.999
M80-M85 Disorders of bone density and structure	0.998	0.002	0.000
M31.6 Other giant cell arteritis	0.998	0.002	0.000
J40-J47 Chronic lower respiratory diseases	0.997	0.003	0.000
M05 Seropositive rheumatoid arthritis	0.997	0.003	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.994	0.006	0.000
J45 Asthma	0.993	0.007	0.000
Chapter VII Diseases of the eye and adnexa	0.992	0.008	0.000
J45.9 Asthma, unspecified	0.991	0.009	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.986	0.014	0.000
M81 Osteoporosis without pathological fracture	0.982	0.018	0.000
H90-H95 Other disorders of ear	0.982	0.018	0.000
Chapter XX External causes of morbidity and mortality	0.980	0.020	0.000
H53-H54 Visual disturbances and blindness	0.973	0.027	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.972	0.028	0.000
M81.9 Osteoporosis, unspecified	0.964	0.036	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.961	0.039	0.000
H54 Blindness and low vision	0.960	0.040	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.950	0.050	0.000
H72 Perforation of tympanic membrane	0.940	0.060	0.000
J34 Other disorders of nose and nasal sinuses	0.935	0.065	0.000
H60-H62 Diseases of external ear	0.931	0.069	0.000
M30 Polyarteritis nodosa and related conditions	0.930	0.070	0.000
H74 Other disorders of middle ear and mastoid	0.929	0.071	0.000
J46 Status asthmaticus	0.925	0.075	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.923	0.077	0.000
H91 Other hearing loss	0.919	0.081	0.000
J33.8 Other polyp of sinus	0.914	0.086	0.000
W00-W19 Falls	0.912	0.088	0.000
H00 Hordeolum and chalazion	0.911	0.089	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.908	0.092	0.000
H04 Disorders of lachrymal system	0.907	0.093	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.904	0.096	0.000
M86-M90 Other osteopathies	0.902	0.098	0.000
H92 Otalgia and effusion of ear	0.901	0.099	0.000
H66 Suppurative and unspecified otitis media	0.897	0.103	0.000
M84 Disorders of continuity of bone	0.893	0.107	0.000
M45-M49 Spondylopathies	0.892	0.108	0.000
M80 Osteoporosis with pathological fracture	0.890	0.110	0.000
M81.98 Osteoporosis, unspecified (Other)	0.890	0.110	0.000
H60 Otitis externa	0.887	0.113	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.884	0.116	0.000
H91.9 Hearing loss, unspecified	0.874	0.126	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.873	0.127	0.000
J34.3 Hypertrophy of nasal turbinates	0.870	0.130	0.000
H65 Nonsuppurative otitis media	0.869	0.131	0.000
H54.7 Unspecified visual loss	0.868	0.132	0.000
M65-M68 Disorders of synovium and tendon	0.867	0.133	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.867	0.133	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.864	0.136	0.000
H54.4 Blindness, one eye	0.856	0.144	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.852	0.148	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.851	0.149	0.000
S80-S89 Injuries to the knee and lower leg	0.850	0.150	0.000
M24 Other specific joint derangements	0.849	0.151	0.000
M82 Osteoporosis in diseases classified elsewhere	0.849	0.151	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.848	0.152	0.000
S60-S69 Injuries to the wrist and hand	0.847	0.153	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.845	0.155	0.000
J42 Unspecified chronic bronchitis	0.834	0.166	0.000
M89 Other disorders of bone	0.834	0.166	0.000
J44 Other chronic obstructive pulmonary disease	0.834	0.166	0.000
M21 Other acquired deformities of limbs	0.833	0.167	0.000
H54.9 Unspecified visual impairment (binocular)	0.831	0.169	0.000
L60-L75 Disorders of skin appendages	0.830	0.170	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.829	0.171	0.000
J34.2 Deviated nasal septum	0.828	0.172	0.000
H72.0 Central perforation of tympanic membrane	0.824	0.176	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.823	0.177	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.823	0.177	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.823	0.177	0.000
H01 Other inflammation of eyelid	0.822	0.177	0.000
H73 Other disorders of tympanic membrane	0.822	0.178	0.000
M45 Ankylosing spondylitis	0.818	0.182	0.000
S50-S59 Injuries to the elbow and forearm	0.817	0.183	0.000
J20-J22 Other acute lower respiratory infections	0.817	0.183	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.816	0.184	0.000
M31.3 Wegener's granulomatosis	0.813	0.187	0.000
H69 Other disorders of Eustachian tube	0.810	0.190	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.810	0.190	0.000
H00.1 Chalazion	0.808	0.192	0.000
J35 Chronic diseases of tonsils and adenoids	0.807	0.193	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.806	0.194	0.000
H92.0 Otalgia	0.805	0.195	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.803	0.197	0.000
H54.0 Blindness, both eyes	0.802	0.198	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.802	0.198	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.802	0.198	0.000
Y52 Agents primarily affecting the cardiovascular system	0.801	0.199	0.000
V40-V49 Car occupant injured in transport accident	0.799	0.201	0.000
H65.3 Chronic mucoid otitis media	0.799	0.201	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.798	0.202	0.000
H04.1 Other disorders of lachrymal gland	0.796	0.204	0.000
M06.3 Rheumatoid nodule	0.796	0.204	0.000
S61 Open wound of wrist and hand	0.795	0.205	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.791	0.209	0.000
H60.9 Otitis externa, unspecified	0.786	0.214	0.000
M81.2 Osteoporosis of disuse	0.785	0.215	0.000
W50-W64 Exposure to animate mechanical forces	0.785	0.215	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.783	0.216	0.000
W10 Fall on and from stairs and steps	0.782	0.218	0.000
V10-V19 Pedal cyclist injured in transport accident	0.782	0.218	0.000
M34 Systemic sclerosis	0.778	0.222	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.776	0.224	0.000
W07 Fall involving chair	0.773	0.227	0.000
H66.9 Otitis media, unspecified	0.772	0.228	0.000
H60.8 Other otitis externa	0.772	0.228	0.000
M24.5 Contracture of joint	0.771	0.229	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.769	0.231	0.000
H74.4 Polyp of middle ear	0.768	0.232	0.000
L71 Rosacea	0.767	0.233	0.000
M14 Arthropathies in other diseases classified elsewhere	0.766	0.234	0.000
M06.4 Inflammatory polyarthropathy	0.766	0.234	0.000
W06 Fall involving bed	0.766	0.234	0.000
M85 Other disorders of bone density and structure	0.760	0.240	0.000
M30.0 Polyarteritis nodosa	0.760	0.240	0.000
M13 Other arthritis	0.759	0.241	0.000
H90 Conductive and sensorineural hearing loss	0.758	0.242	0.000
S51 Open wound of forearm	0.757	0.243	0.000
H71 Cholesteatoma of middle ear	0.757	0.243	0.000
J34.1 Cyst and mucocele of nose and nasal sinus	0.756	0.244	0.000
S89 Other and unspecified injuries of lower leg	0.755	0.245	0.000
M00-M03 Infectious arthropathies	0.754	0.246	0.000
M89.8 Other specified disorders of bone	0.753	0.247	0.000
H66.3 Other chronic suppurative otitis media	0.750	0.250	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.750	0.250	0.000
H92.1 Otorrhoea	0.747	0.253	0.000
M86 Osteomyelitis	0.747	0.253	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.745	0.255	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.745	0.255	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.743	0.257	0.000
M60-M63 Disorders of muscles	0.743	0.257	0.000
M82.1 Osteoporosis in endocrine disorders	0.741	0.259	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.740	0.260	0.000
Y48 Anaesthetics and therapeutic gases	0.740	0.260	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.739	0.261	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.738	0.262	0.000
H05 Disorders of orbit	0.738	0.262	0.000
M91-M94 Chondropathies	0.731	0.269	0.000
H10-H13 Disorders of conjunctiva	0.730	0.270	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.730	0.270	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.728	0.272	0.000
S81 Open wound of lower leg	0.728	0.272	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.727	0.273	0.000
M46 Other inflammatory spondylopathies	0.726	0.274	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.725	0.275	0.000
M67 Other disorders of synovium and tendon	0.725	0.275	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.725	0.275	0.000
Y45.1 Salicylates	0.725	0.275	0.000
T00-T07 Injuries involving multiple body regions	0.724	0.276	0.000
W01 Fall on same level from slipping, tripping and stumbling	0.723	0.277	0.000
M84.4 Pathological fracture, not elsewhere classified	0.723	0.277	0.000
L73 Other follicular disorders	0.721	0.279	0.000
H04.8 Other disorders of lachrymal system	0.719	0.281	0.000
H74.0 Tympanosclerosis	0.719	0.281	0.000
J22 Unspecified acute lower respiratory infection	0.719	0.281	0.000
H16 Keratitis	0.718	0.282	0.000
S82 Fracture of lower leg, including ankle	0.718	0.282	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.717	0.283	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
J33.1 Polypoid sinus degeneration	0.717	0.283	0.000
M12 Other specific arthropathies	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M08 Juvenile arthritis	0.717	0.283	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283	0.000
M33 Dermatopolymyositis	0.717	0.283	0.000
M32 Systemic lupus erythematosus	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
M06.8 Other specified rheumatoid arthritis	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.717	0.283	0.000
M35.8 Other specified systemic involvement of connective tissue	0.717	0.283	0.000
M35.7 Hypermobility syndrome	0.717	0.283	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.717	0.283	0.000
M35.5 Multifocal fibrosclerosis	0.717	0.283	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.717	0.283	0.000
M35.2 Behcet's disease	0.717	0.283	0.000
M35.1 Other overlap syndromes	0.717	0.283	0.000
J37 Chronic laryngitis and laryngotracheitis	0.717	0.283	0.000
M31.9 Necrotising vasculopathy, unspecified	0.716	0.284	0.000
M31.8 Other specified necrotising vasculopathies	0.716	0.284	0.000
M31.7 Microscopic polyangiitis	0.716	0.284	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.716	0.284	0.000
M31.2 Lethal midline granuloma	0.716	0.284	0.000
M31.1 Thrombotic microangiopathy	0.716	0.284	0.000
M31.0 Hypersensitivity angiitis	0.716	0.284	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.716	0.284	0.000
H68 Eustachian salpingitis and obstruction	0.716	0.284	0.000
H67 Otitis media in diseases classified elsewhere	0.716	0.284	0.000
V80-V89 Other land transport accidents	0.716	0.284	0.000
M83 Adult osteomalacia	0.716	0.284	0.000
L71.9 Rosacea, unspecified	0.716	0.284	0.000
J41 Simple and mucopurulent chronic bronchitis	0.715	0.285	0.000
M05.8 Other seropositive rheumatoid arthritis	0.714	0.285	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.714	0.285	0.000
M05.2 Rheumatoid vasculitis	0.714	0.285	0.000
M05.1 Rheumatoid lung disease	0.714	0.285	0.000
M05.0 Felty's syndrome	0.714	0.285	0.000
S61.1 Open wound of finger(s) with damage to nail	0.714	0.286	0.000
J35.0 Chronic tonsillitis	0.713	0.287	0.000
M81.4 Drug-induced osteoporosis	0.713	0.287	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.713	0.287	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.713	0.287	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.713	0.287	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.713	0.287	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.713	0.287	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.713	0.287	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.713	0.287	0.000
J45.8 Mixed asthma	0.712	0.288	0.000
J45.1 Nonallergic asthma	0.712	0.288	0.000
S69 Other and unspecified injuries of wrist and hand	0.710	0.290	0.000
W15 Fall from cliff	0.710	0.290	0.000
M84.0 Malunion of fracture	0.710	0.290	0.000
H04.9 Disorder of lachrymal system, unspecified	0.709	0.291	0.000
T79-T79 Certain early complications of trauma	0.709	0.291	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.709	0.291	0.000
X60-X84 Intentional self-harm	0.708	0.292	0.000
H01.0 Blepharitis	0.708	0.292	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.707	0.293	0.000
M81.8 Other osteoporosis	0.704	0.296	0.000
M81.6 Localised osteoporosis [Lequesne]	0.704	0.296	0.000
M81.5 Idiopathic osteoporosis	0.704	0.296	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.704	0.296	0.000
M81.1 Postoophorectomy osteoporosis	0.704	0.296	0.000
M81.0 Postmenopausal osteoporosis	0.704	0.296	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.704	0.296	0.000
Y35-Y36 Legal intervention and operations of war	0.702	0.297	0.000
Y10-Y34 Event of undetermined intent	0.702	0.297	0.000
Y00-Y09 Assault	0.702	0.297	0.000
X85-X99 Assault	0.702	0.297	0.000
X30-X39 Exposure to forces of nature	0.702	0.297	0.000
X10-X19 Contact with heat and hot substances	0.702	0.297	0.000
X00-X09 Exposure to smoke, fire and flames	0.702	0.297	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.702	0.297	0.000
W75-W84 Other accidental threats to breathing	0.702	0.297	0.000
W65-W74 Accidental drowning and submersion	0.702	0.297	0.000
V98-V99 Other and unspecified transport accidents	0.702	0.297	0.000
V95-V97 Air and space transport accidents	0.702	0.297	0.000
V90-V94 Water transport accidents	0.702	0.297	0.000
V70-V79 Bus occupant injured in transport accident	0.702	0.297	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.702	0.297	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.702	0.297	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.702	0.297	0.000
V01-V09 Pedestrian injured in transport accident	0.702	0.297	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.702	0.298	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.701	0.299	0.000
X20-X29 Contact with venomous animals and plants	0.700	0.300	0.000
H04.5 Stenosis and insufficiency of lachrymal passages	0.699	0.301	0.000
H95.1 Other disorders following mastoidectomy	0.698	0.302	0.000
H70 Mastoiditis and related conditions	0.697	0.302	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.697	0.303	0.000
M89.0 Algoneurodystrophy	0.697	0.303	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.697	0.303	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.697	0.303	0.000
X50-X57 Overexertion, travel and privation	0.697	0.303	0.000
T92 Sequelae of injuries of upper limb	0.696	0.304	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.696	0.304	0.000
S10-S19 Injuries to the neck	0.696	0.304	0.000
H73.8 Other specified disorders of tympanic membrane	0.695	0.305	0.000
S60 Superficial injury of wrist and hand	0.695	0.305	0.000
H60.3 Other infective otitis externa	0.694	0.306	0.000
M24.54 Contracture of joint (Hand)	0.693	0.307	0.000
Y57 Other and unspecified drugs and medicaments	0.693	0.307	0.000
W17 Other fall from one level to another	0.693	0.307	0.000
S51.0 Open wound of elbow	0.693	0.307	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.692	0.308	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.691	0.309	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.691	0.309	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.691	0.309	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.691	0.309	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.691	0.309	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.691	0.309	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.691	0.309	0.000
H53 Visual disturbances	0.691	0.309	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.690	0.310	0.000
H54.6 Unqualified visual loss, one eye	0.688	0.312	0.000
H54.5 Low vision, one eye	0.688	0.312	0.000
H54.3 Unqualified visual loss, both eyes	0.688	0.312	0.000
H54.2 Low vision, both eyes	0.688	0.312	0.000
H54.1 Blindness, one eye, low vision, other eye	0.688	0.312	0.000
S89.9 Unspecified injury of lower leg	0.688	0.312	0.000
J95-J99 Other diseases of the respiratory system	0.688	0.312	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.684	0.316	0.000
M65 Synovitis and tenosynovitis	0.684	0.316	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.683	0.316	0.000
Y45.0 Opioids and related analgesics	0.683	0.317	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.682	0.318	0.000
H52 Disorders of refraction and accommodation	0.682	0.318	0.000
M21.3 Wrist or foot drop (acquired)	0.681	0.319	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.681	0.319	0.000
W13 Fall from, out of or through building or structure	0.680	0.319	0.000
T91 Sequelae of injuries of neck and trunk	0.677	0.323	0.000
M49 Spondylopathies in diseases classified elsewhere	0.676	0.324	0.000
H69.9 Eustachian tube disorder, unspecified	0.676	0.324	0.000
H43-H45 Disorders of vitreous body and globe	0.674	0.326	0.000
H72.2 Other marginal perforations of tympanic membrane	0.674	0.326	0.000
H72.1 Attic perforation of tympanic membrane	0.674	0.326	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.672	0.328	0.000
W10.4 Street and highway	0.672	0.328	0.000
V20-V29 Motorcycle rider injured in transport accident	0.671	0.329	0.000
M50-M54 Other dorsopathies	0.669	0.330	0.001
H60.1 Cellulitis of external ear	0.668	0.332	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.667	0.332	0.000
H20 Iridocyclitis	0.667	0.332	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.667	0.333	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.667	0.333	0.000
M30.2 Juvenile polyarteritis	0.667	0.333	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.666	0.334	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.666	0.334	0.000
H74.1 Adhesive middle ear disease	0.666	0.334	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.666	0.334	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.666	0.334	0.000
W08 Fall involving other furniture	0.665	0.335	0.000
H72.8 Other perforations of tympanic membrane	0.664	0.336	0.000
L20-L30 Dermatitis and eczema	0.663	0.336	0.000
J85 Abscess of lung and mediastinum	0.663	0.337	0.000
H90.3 Sensorineural hearing loss, bilateral	0.663	0.337	0.000
M21.0 Valgus deformity, not elsewhere classified	0.662	0.338	0.000
T33-T35 Frostbite	0.662	0.338	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.662	0.338	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.662	0.338	0.000
W06.0 Home	0.661	0.339	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.659	0.341	0.000
H91.3 Deaf mutism, not elsewhere classified	0.659	0.341	0.000
H91.2 Sudden idiopathic hearing loss	0.659	0.341	0.000
H91.1 Presbycusis	0.659	0.341	0.000
H91.0 Ototoxic hearing loss	0.659	0.341	0.000
L84 Corns and callosities	0.658	0.342	0.000
S82.1 Fracture of upper end of tibia	0.657	0.343	0.000
H91.8 Other specified hearing loss	0.656	0.344	0.000
J86 Pyothorax	0.655	0.345	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.655	0.345	0.000
W16 Diving or jumping into water causing injury other than drowning or submersion	0.654	0.346	0.000
W14 Fall from tree	0.654	0.346	0.000
W12 Fall on and from scaffolding	0.654	0.346	0.000
W11 Fall on and from ladder	0.654	0.346	0.000
W09 Fall involving playground equipment	0.654	0.346	0.000
W05 Fall involving wheelchair	0.654	0.346	0.000
W04 Fall while being carried or supported by other persons	0.654	0.346	0.000
W03 Other fall on same level due to collision with, or pushing by, another person	0.654	0.346	0.000
W00 Fall on same level involving ice and snow	0.654	0.346	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.654	0.346	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.652	0.348	0.000
Y59 Other and unspecified vaccines and biological substances	0.651	0.349	0.000
Y58 Bacterial vaccines	0.651	0.349	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.651	0.349	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.651	0.349	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.651	0.349	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.651	0.349	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.651	0.349	0.000
H04.6 Other changes in lachrymal passages	0.650	0.350	0.000
H04.4 Chronic inflammation of lachrymal passages	0.650	0.350	0.000
H04.0 Dacryoadenitis	0.650	0.350	0.000
J45.0 Predominantly allergic asthma	0.649	0.351	0.000
M66 Spontaneous rupture of synovium and tendon	0.648	0.352	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.648	0.352	0.000
J40 Bronchitis, not specified as acute or chronic	0.648	0.352	0.000
H50 Other strabismus	0.647	0.352	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.647	0.353	0.000
H92.2 Otorrhagia	0.646	0.354	0.000
J00-J06 Acute upper respiratory infections	0.646	0.354	0.000
T23 Burn and corrosion of wrist and hand	0.645	0.355	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.645	0.355	0.000
H66.4 Suppurative otitis media, unspecified	0.643	0.356	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.643	0.356	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.643	0.356	0.000
H66.0 Acute suppurative otitis media	0.643	0.356	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.642	0.358	0.000
M84.9 Disorder of continuity of bone, unspecified	0.640	0.360	0.000
M84.8 Other disorders of continuity of bone	0.640	0.360	0.000
M84.3 Stress fracture, not elsewhere classified	0.640	0.360	0.000
M84.2 Delayed union of fracture	0.640	0.360	0.000
S50 Superficial injury of forearm	0.640	0.360	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.639	0.360	0.000
M80.8 Other osteoporosis with pathological fracture	0.638	0.362	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.638	0.362	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.638	0.362	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.638	0.362	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.638	0.362	0.000
T51 Toxic effect of alcohol	0.638	0.362	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.637	0.363	0.000
W07.0 Home	0.637	0.363	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.636	0.364	0.000
M67.8 Other specified disorders of synovium and tendon	0.636	0.364	0.000
H60.5 Acute otitis externa, non-infective	0.636	0.364	0.000
H60.4 Cholesteatoma of external ear	0.636	0.364	0.000
H60.2 Malignant otitis externa	0.636	0.364	0.000
H60.0 Abscess of external ear	0.636	0.364	0.000
Y44 Agents primarily affecting blood constituents	0.636	0.364	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.636	0.364	0.000
Chapter XXII Codes for special purposes	0.635	0.365	0.000
X59 Exposure to unspecified factor	0.635	0.365	0.000
H61 Other disorders of external ear	0.634	0.366	0.000
Q66 Congenital deformities of feet	0.633	0.367	0.000
M48 Other spondylopathies	0.633	0.367	0.000
S90-S99 Injuries to the ankle and foot	0.633	0.367	0.000
V48 Car occupant injured in noncollision transport accident	0.632	0.367	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.632	0.368	0.000
L80 Vitiligo	0.632	0.368	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.632	0.368	0.000
H65.2 Chronic serous otitis media	0.631	0.369	0.000
L89 Decubitus ulcer	0.631	0.369	0.000
S59 Other and unspecified injuries of forearm	0.630	0.369	0.000
M90 Osteopathies in diseases classified elsewhere	0.629	0.371	0.000
L72 Follicular cysts of skin and subcutaneous tissue	0.628	0.372	0.000
W20-W49 Exposure to inanimate mechanical forces	0.628	0.372	0.000
T66-T78 Other and unspecified effects of external causes	0.627	0.373	0.000
S65 Injury of blood vessels at wrist and hand level	0.627	0.373	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.627	0.373	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.626	0.374	0.000
M24.0 Loose body in joint	0.626	0.374	0.000
W18 Other fall on same level	0.626	0.374	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.625	0.375	0.000
T21 Burn and corrosion of trunk	0.624	0.376	0.000
H65.1 Other acute nonsuppurative otitis media	0.623	0.377	0.000
H65.0 Acute serous otitis media	0.623	0.377	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.623	0.377	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.623	0.377	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.622	0.378	0.000
S61.7 Multiple open wounds of wrist and hand	0.622	0.378	0.000
M21.2 Flexion deformity	0.622	0.378	0.000
T98 Sequelae of other and unspecified effects of external causes	0.622	0.378	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.621	0.379	0.000
L70 Acne	0.621	0.379	0.000
M11 Other crystal arthropathies	0.619	0.380	0.000
M89.5 Osteolysis	0.620	0.380	0.000
H18 Other disorders of cornea	0.619	0.380	0.000
L10-L14 Bullous disorders	0.619	0.381	0.000
Y48.3 Local anaesthetics	0.619	0.381	0.000
T56 Toxic effect of metals	0.619	0.381	0.000
Q60-Q64 Congenital malformations of the urinary system	0.617	0.383	0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.616	0.384	0.000
L50-L54 Urticaria and erythema	0.616	0.384	0.000
M24.51 Contracture of joint (Shoulder region)	0.616	0.384	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.615	0.385	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.615	0.385	0.000
W07.9 Unspecified place	0.614	0.385	0.000
S51.9 Open wound of forearm, part unspecified	0.614	0.386	0.000
M10 Gout	0.613	0.387	0.000
S82.10 Fracture of upper end of tibia (closed)	0.613	0.387	0.000
S81.0 Open wound of knee	0.612	0.387	0.000
M86.9 Osteomyelitis, unspecified	0.612	0.388	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.610	0.390	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.610	0.390	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.610	0.390	0.000
Q35-Q37 Cleft lip and cleft palate	0.610	0.390	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.610	0.390	0.000
S88 Traumatic amputation of lower leg	0.609	0.391	0.000
S87 Crushing injury of lower leg	0.609	0.391	0.000
S85 Injury of blood vessels at lower leg level	0.609	0.391	0.000
S84 Injury of nerves at lower leg level	0.609	0.391	0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus	0.609	0.391	0.000
M24.9 Joint derangement, unspecified	0.609	0.391	0.000
M24.7 Protrusio acetabuli	0.609	0.391	0.000
M24.6 Ankylosis of joint	0.609	0.391	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.609	0.391	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.608	0.391	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.608	0.391	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.608	0.391	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.608	0.392	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.608	0.392	0.000
H17 Corneal scars and opacities	0.608	0.392	0.000
H15 Disorders of sclera	0.608	0.392	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.607	0.393	0.000
M24.2 Disorder of ligament	0.607	0.393	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.607	0.393	0.000
M84.01 Malunion of fracture (Shoulder region)	0.606	0.394	0.000
H01.8 Other specified inflammation of eyelid	0.605	0.395	0.000
L72.0 Epidermal cyst	0.605	0.395	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.603	0.397	0.000
Y77 Ophthalmic devices associated with adverse incidents	0.603	0.397	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.603	0.397	0.000
M13.9 Arthritis, unspecified	0.602	0.398	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.601	0.399	0.000
W55 Bitten or struck by other mammals	0.600	0.400	0.000
H52.1 Myopia	0.600	0.400	0.000
J32 Chronic sinusitis	0.600	0.400	0.000
M07 Psoriatic and enteropathic arthropathies	0.599	0.400	0.000
H04.2 Epiphora	0.599	0.401	0.000
M14.6 Neuropathic arthropathy	0.599	0.401	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations