TreeWAS – Variant ID: rs3774959

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C85.1 B-cell lymphoma, unspecified	0.834	0.166	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.834	0.166	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.822	0.178	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.761	0.239	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.758	0.242	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.709	0.291	0.000
C83.3 Large cell (diffuse)	0.706	0.294	0.000
C83.0 Small cell (diffuse)	0.660	0.340	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.650	0.350	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.649	0.351	0.000
C95 Leukaemia of unspecified cell type	0.632	0.368	0.000
C83.5 Lymphoblastic (diffuse)	0.632	0.368	0.000
C88 Malignant immunoproliferative diseases	0.602	0.398	0.000
C85.0 Lymphosarcoma	0.598	0.402	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.596	0.404	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.594	0.406	0.000
C86 Other specified types of T/NK-cell lymphoma	0.581	0.419	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.563	0.437	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.546	0.454	0.000
C94 Other leukaemias of specified cell type	0.546	0.454	0.000
C93 Monocytic leukaemia	0.545	0.455	0.000
C83.1 Small cleaved cell (diffuse)	0.544	0.455	0.000
C83.6 Undifferentiated (diffuse)	0.543	0.456	0.000
C83.4 Immunoblastic (diffuse)	0.543	0.456	0.000
C83.2 Mixed small and large cell (diffuse)	0.543	0.456	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.514	0.486	0.000
C95.9 Leukaemia, unspecified	0.509	0.491	0.000
C90.0 Multiple myeloma	0.487	0.513	0.000
C84.4 Peripheral T-cell lymphoma	0.481	0.519	0.000
C95.0 Acute leukaemia of unspecified cell type	0.481	0.519	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.474	0.526	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.469	0.531	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.460	0.540	0.000
C91 Lymphoid leukaemia	0.455	0.545	0.000
C95.7 Other leukaemia of unspecified cell type	0.453	0.547	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.453	0.547	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.452	0.548	0.000
C83.7 Burkitt's tumour	0.435	0.564	0.000
C88.9 Malignant immunoproliferative disease, unspecified	0.431	0.568	0.000
C88.7 Other malignant immunoproliferative diseases	0.431	0.568	0.000
C88.3 Immunoproliferative small intestinal disease	0.431	0.568	0.000
C88.2 Gamma heavy chain disease	0.431	0.568	0.000
C88.1 Alpha heavy chain disease	0.431	0.568	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.426	0.574	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.426	0.574	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.426	0.574	0.000
C84.3 Lymphoepithelioid lymphoma	0.426	0.574	0.000
C84.2 T-zone lymphoma	0.426	0.574	0.000
C84.1 Sezary's diease	0.426	0.574	0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.416	0.583	0.000
C86.4 Blastic NK-cell lymphoma	0.416	0.583	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.416	0.583	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.416	0.583	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.416	0.583	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.416	0.583	0.000
C90.1 Plasma cell leukaemia	0.410	0.590	0.000
C84.0 Mycosis fungoides	0.407	0.593	0.000
C90.3 Solitary plasmacytoma	0.401	0.599	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.398	0.602	0.000
C84.5 Other and unspecified T-cell lymphomas	0.395	0.605	0.000
C94.7 Other specified leukaemias	0.391	0.608	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.391	0.608	0.000
C94.5 Acute myelofibrosis	0.391	0.608	0.000
C94.4 Acute panmyelosis	0.391	0.608	0.000
C94.3 Mast cell leukaemia	0.391	0.608	0.000
C94.2 Acute megakaryoblastic leukaemia	0.391	0.608	0.000
C94.1 Chronic erythraemia	0.391	0.608	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.391	0.608	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.391	0.608	0.000
C96.8 Histiocytic sarcoma	0.391	0.608	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.391	0.608	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.391	0.608	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.391	0.608	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.391	0.608	0.000
C96.3 True histiocytic lymphoma	0.391	0.608	0.000
C96.2 Malignant mast cell tumour	0.391	0.608	0.000
C96.1 Malignant histiocytosis	0.391	0.608	0.000
C96.0 Letterer-Siwe disease	0.391	0.608	0.000
C93.9 Monocytic leukaemia, unspecified	0.391	0.609	0.000
C93.7 Other monocytic leukaemia	0.391	0.609	0.000
C93.3 Juvenile myelomonocytic leukaemia	0.391	0.609	0.000
C93.2 Subacute monocytic leukaemia	0.391	0.609	0.000
C93.0 Acute monocytic leukaemia	0.391	0.609	0.000
C93.1 Chronic monocytic leukaemia	0.390	0.610	0.000
C91.9 Lymphoid leukaemia, unspecified	0.388	0.612	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.380	0.620	0.000
C91.5 Adult T-cell leukaemia	0.370	0.630	0.000
C82.0 Small cleaved cell, follicular	0.350	0.650	0.000
C82.4 Follicular lymphoma grade IIIb	0.347	0.652	0.000
C91.0 Acute lymphoblastic leukaemia	0.346	0.654	0.000
C82.6 Cutaneous follicle centre lymphoma	0.337	0.663	0.000
C82.5 Diffuse follicle centre lymphoma	0.337	0.663	0.000
C82.2 Large cell, follicular	0.334	0.666	0.000
C82.3 Follicular lymphoma grade IIIa	0.328	0.672	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.326	0.674	0.000
C91.7 Other lymphoid leukaemia	0.326	0.674	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.326	0.674	0.000
C91.3 Prolymphocytic leukaemia	0.326	0.674	0.000
C91.2 Subacute lymphocytic leukaemia	0.326	0.674	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.280	0.720	0.000
C90.2 Plasmacytoma, extramedullary	0.260	0.740	0.000
C81 Hodgkin's disease	0.258	0.741	0.001
C92 Myeloid leukaemia	0.245	0.755	0.000
C81.2 Mixed cellularity	0.209	0.790	0.001
C91.4 Hairy-cell leukaemia	0.200	0.799	0.000
D70 Agranulocytosis	0.200	0.800	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.187	0.813	0.000
C81.7 Other Hodgkin's disease	0.185	0.814	0.001
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.185	0.814	0.001
C81.3 Lymphocytic depletion	0.185	0.814	0.001
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.176	0.824	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.176	0.824	0.000
C92.5 Acute myelomonocytic leukaemia	0.176	0.824	0.000
C92.3 Myeloid sarcoma	0.176	0.824	0.000
C92.2 Subacute myeloid leukaemia	0.176	0.824	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.175	0.825	0.000
C92.0 Acute myeloid leukaemia	0.174	0.826	0.000
C92.9 Myeloid leukaemia, unspecified	0.169	0.831	0.000
C81.0 Lymphocytic predominance	0.165	0.834	0.001
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.166	0.834	0.000
D55-D59 Haemolytic anaemias	0.165	0.835	0.000
D50-D53 Nutritional anaemias	0.162	0.838	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.159	0.841	0.000
D51 Vitamin B12 deficiency anaemia	0.159	0.841	0.000
D73 Diseases of spleen	0.158	0.842	0.000
D80-D89 Certain disorders involving the immune mechanism	0.150	0.850	0.000
D59 Acquired haemolytic anaemia	0.149	0.851	0.000
C92.4 Acute promyelocytic leukaemia	0.145	0.854	0.000
D58 Other hereditary haemolytic anaemias	0.145	0.855	0.000
D73.5 Infarction of spleen	0.143	0.857	0.000
C92.7 Other myeloid leukaemia	0.142	0.858	0.000
D72 Other disorders of white blood cells	0.139	0.861	0.000
D74 Methaemoglobinaemia	0.135	0.865	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.135	0.865	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.135	0.865	0.000
D59.1 Other autoimmune haemolytic anaemias	0.133	0.867	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.132	0.868	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.131	0.869	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.130	0.870	0.000
D73.3 Abscess of spleen	0.127	0.873	0.000
D73.1 Hypersplenism	0.126	0.874	0.000
D80 Immunodeficiency with predominantly antibody defects	0.124	0.876	0.000
D57 Sickle-cell disorders	0.122	0.877	0.000
D86 Sarcoidosis	0.121	0.879	0.000
D72.8 Other specified disorders of white blood cells	0.120	0.880	0.000
D73.9 Disease of spleen, unspecified	0.119	0.881	0.000
D55 Anaemia due to enzyme disorders	0.118	0.882	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.117	0.882	0.000
D60-D64 Aplastic and other anaemias	0.117	0.883	0.000
D75 Other diseases of blood and blood-forming organs	0.115	0.885	0.000
D58.2 Other haemoglobinopathies	0.115	0.885	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.114	0.886	0.000
D51.2 Transcobalamin II deficiency	0.114	0.886	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.114	0.886	0.000
D52 Folate deficiency anaemia	0.114	0.886	0.000
D73.2 Chronic congestive splenomegaly	0.114	0.886	0.000
D84 Other immunodeficiencies	0.111	0.889	0.000
D83 Common variable immunodeficiency	0.110	0.890	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.110	0.890	0.000
D56 Thalassaemia	0.109	0.891	0.000
D86.0 Sarcoidosis of lung	0.108	0.892	0.000
D73.4 Cyst of spleen	0.108	0.892	0.000
D81 Combined immunodeficiencies	0.107	0.893	0.000
D53 Other nutritional anaemias	0.107	0.893	0.000
D59.8 Other acquired haemolytic anaemias	0.107	0.893	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.107	0.893	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.107	0.893	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.107	0.893	0.000
D59.3 Haemolytic-uraemic syndrome	0.107	0.893	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.107	0.893	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.107	0.893	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.106	0.894	0.000
D82 Immunodeficiency associated with other major defects	0.105	0.895	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.104	0.896	0.000
D58.1 Hereditary elliptocytosis	0.104	0.896	0.000
D61 Other aplastic anaemias	0.103	0.897	0.000
C81.9 Hodgkin's disease, unspecified	0.100	0.899	0.001
D72.9 Disorder of white blood cells, unspecified	0.100	0.900	0.000
D72.0 Genetic anomalies of leukocytes	0.100	0.900	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.100	0.900	0.000
D73.8 Other diseases of spleen	0.099	0.901	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.098	0.902	0.000
D69 Purpura and other haemorrhagic conditions	0.097	0.903	0.000
D74.9 Methaemoglobinaemia, unspecified	0.097	0.903	0.000
D74.8 Other methaemoglobinaemias	0.097	0.903	0.000
D74.0 Congenital methaemoglobinaemia	0.097	0.903	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.095	0.905	0.000
L40 Psoriasis	0.095	0.905	0.000
L40.0 Psoriasis vulgaris	0.094	0.906	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.094	0.906	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.093	0.906	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.093	0.906	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.093	0.906	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.093	0.907	0.000
D86.9 Sarcoidosis, unspecified	0.092	0.908	0.000
C92.1 Chronic myeloid leukaemia	0.092	0.908	0.000
D57.1 Sickle-cell anaemia without crisis	0.092	0.908	0.000
D61.9 Aplastic anaemia, unspecified	0.090	0.910	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.089	0.911	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.089	0.911	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.089	0.911	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.089	0.911	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.089	0.911	0.000
D76.3 Other histiocytosis syndromes	0.089	0.911	0.000
L40.5 Arthropathic psoriasis	0.089	0.911	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.088	0.911	0.000
D57.8 Other sickle-cell disorders	0.088	0.912	0.000
D57.3 Sickle-cell trait	0.088	0.912	0.000
D57.2 Double heterozygous sickling disorders	0.088	0.912	0.000
D57.0 Sickle-cell anaemia with crisis	0.088	0.912	0.000
D58.0 Hereditary spherocytosis	0.087	0.912	0.000
L40.3 Pustulosis palmaris et plantaris	0.087	0.913	0.000
D86.1 Sarcoidosis of lymph nodes	0.086	0.914	0.000
D69.9 Haemorrhagic condition, unspecified	0.085	0.915	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.085	0.915	0.000
D55.8 Other anaemias due to enzyme disorders	0.085	0.915	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.085	0.915	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.085	0.915	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.085	0.915	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.085	0.915	0.000
D84.9 Immunodeficiency, unspecified	0.085	0.915	0.000
D50 Iron deficiency anaemia	0.085	0.915	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.084	0.915	0.000
L40.9 Psoriasis, unspecified	0.084	0.916	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.084	0.916	0.000
D75.1 Secondary polycythaemia	0.083	0.917	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.083	0.917	0.000
D83.9 Common variable immunodeficiency, unspecified	0.082	0.918	0.000
D52.8 Other folate deficiency anaemias	0.082	0.918	0.000
D52.1 Drug-induced folate deficiency anaemia	0.082	0.918	0.000
D52.0 Dietary folate deficiency anaemia	0.082	0.918	0.000
D64 Other anaemias	0.080	0.920	0.000
D86.3 Sarcoidosis of skin	0.080	0.920	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.080	0.920	0.000
D84.1 Defects in the complement system	0.079	0.921	0.000
D52.9 Folate deficiency anaemia, unspecified	0.079	0.921	0.000
D61.0 Constitutional aplastic anaemia	0.079	0.921	0.000
D83.8 Other common variable immunodeficiencies	0.079	0.921	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.079	0.921	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.079	0.921	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.079	0.921	0.000
L40.8 Other psoriasis	0.079	0.921	0.000
D56.3 Thalassaemia trait	0.079	0.921	0.000
D84.8 Other specified immunodeficiencies	0.078	0.922	0.000
D56.9 Thalassaemia, unspecified	0.078	0.922	0.000
D56.8 Other thalassaemias	0.078	0.922	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.078	0.922	0.000
D56.2 Delta-beta thalassaemia	0.078	0.922	0.000
D56.0 Alpha thalassaemia	0.078	0.922	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.078	0.922	0.000
D81.9 Combined immunodeficiency, unspecified	0.077	0.923	0.000
D81.8 Other combined immunodeficiencies	0.077	0.923	0.000
D81.7 Major histocompatibility complex class II deficiency	0.077	0.923	0.000
D81.6 Major histocompatibility complex class I deficiency	0.077	0.923	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.077	0.923	0.000
D81.4 Nezelof's syndrome	0.077	0.923	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.077	0.923	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.077	0.923	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.077	0.923	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.077	0.923	0.000
D53.8 Other specified nutritional anaemias	0.077	0.923	0.000
D53.2 Scorbutic anaemia	0.077	0.923	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.077	0.923	0.000
D53.0 Protein deficiency anaemia	0.077	0.923	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.077	0.923	0.000
D67 Hereditary factor IX deficiency	0.076	0.924	0.000
D61.1 Drug-induced aplastic anaemia	0.076	0.924	0.000
C91.1 Chronic lymphocytic leukaemia	0.075	0.924	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.075	0.925	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.075	0.925	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.075	0.925	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.075	0.925	0.000
D82.2 Immunodeficiency with short-limbed stature	0.075	0.925	0.000
D82.0 Wiskott-Aldrich syndrome	0.075	0.925	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.075	0.925	0.000
D61.8 Other specified aplastic anaemias	0.074	0.926	0.000
D61.3 Idiopathic aplastic anaemia	0.074	0.926	0.000
D61.2 Aplastic anaemia due to other external agents	0.074	0.926	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.073	0.927	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.073	0.927	0.000
D69.1 Qualitative platelet defects	0.073	0.927	0.000
D82.1 Di George's syndrome	0.072	0.927	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.072	0.928	0.000
D89.3 Immune reconstitution syndrome	0.072	0.928	0.000
D86.8 Sarcoidosis of other and combined sites	0.072	0.928	0.000
D72.1 Eosinophilia	0.071	0.929	0.000
D89.1 Cryoglobulinaemia	0.071	0.929	0.000
D69.8 Other specified haemorrhagic conditions	0.070	0.930	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.069	0.930	0.000
L40.2 Acrodermatitis continua	0.068	0.932	0.000
D56.1 Beta thalassaemia	0.067	0.932	0.000
D53.9 Nutritional anaemia, unspecified	0.068	0.932	0.000
D75.2 Essential thrombocytosis	0.067	0.933	0.000
D69.4 Other primary thrombocytopenia	0.067	0.933	0.000
C81.1 Nodular sclerosis	0.063	0.934	0.003
D73.0 Hyposplenism	0.065	0.935	0.000
L40.4 Guttate psoriasis	0.064	0.936	0.000
D64.0 Hereditary sideroblastic anaemia	0.064	0.936	0.000
D69.0 Allergic purpura	0.062	0.938	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.061	0.939	0.000
D60.8 Other acquired pure red cell aplasias	0.061	0.939	0.000
D60.1 Transient acquired pure red cell aplasia	0.061	0.939	0.000
D60.0 Chronic acquired pure red cell aplasia	0.061	0.939	0.000
D50.1 Sideropenic dysphagia	0.060	0.939	0.000
D64.3 Other sideroblastic anaemias	0.059	0.941	0.000
D69.6 Thrombocytopenia, unspecified	0.059	0.941	0.000
L40-L45 Papulosquamous disorders	0.058	0.942	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.058	0.942	0.000
D64.4 Congenital dyserythropoietic anaemia	0.058	0.942	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.058	0.942	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.058	0.942	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.058	0.942	0.000
D69.5 Secondary thrombocytopenia	0.057	0.943	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.057	0.943	0.000
D69.2 Other nonthrombocytopenic purpura	0.056	0.944	0.000
L40.1 Generalised pustular psoriasis	0.056	0.944	0.000
D75.0 Familial erythrocytosis	0.056	0.944	0.000
D62 Acute posthaemorrhagic anaemia	0.055	0.945	0.000
D64.9 Anaemia, unspecified	0.053	0.947	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.052	0.948	0.000
D64.8 Other specified anaemias	0.048	0.952	0.000
L43 Lichen planus	0.047	0.953	0.000
L41 Parapsoriasis	0.046	0.954	0.000
L42 Pityriasis rosea	0.045	0.955	0.000
D66 Hereditary factor VIII deficiency	0.043	0.956	0.000
L44 Other papulosquamous disorders	0.042	0.958	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.042	0.958	0.000
D50.8 Other iron deficiency anaemias	0.038	0.962	0.000
L41.1 Pityriasis lichenoides chronica	0.038	0.962	0.000
L43.0 Hypertrophic lichen planus	0.036	0.964	0.000
L43.8 Other lichen planus	0.035	0.965	0.000
L43.9 Lichen planus, unspecified	0.035	0.965	0.000
L43.3 Subacute (active) lichen planus	0.033	0.966	0.000
L43.2 Lichenoid drug reaction	0.033	0.966	0.000
L43.1 Bullous lichen planus	0.033	0.966	0.000
L41.9 Parapsoriasis, unspecified	0.033	0.966	0.000
L41.8 Other parapsoriasis	0.033	0.966	0.000
L41.5 Retiform parapsoriasis	0.033	0.966	0.000
L41.4 Large plaque parapsoriasis	0.033	0.966	0.000
L41.3 Small plaque parapsoriasis	0.033	0.966	0.000
L41.2 Lymphomatoid papulosis	0.033	0.966	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.033	0.966	0.000
Q61 Cystic kidney disease	0.032	0.968	0.000
Q61.3 Polycystic kidney, unspecified	0.032	0.968	0.000
Q61.0 Congenital single renal cyst	0.031	0.969	0.000
L44.9 Papulosquamous disorder, unspecified	0.030	0.969	0.000
L44.8 Other specified papulosquamous disorders	0.030	0.969	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.030	0.969	0.000
L44.3 Lichen ruber moniliformis	0.030	0.969	0.000
L44.2 Lichen striatus	0.030	0.969	0.000
L44.1 Lichen nitidus	0.030	0.969	0.000
L44.0 Pityriasis rubra pilaris	0.030	0.969	0.000
K51.9 Ulcerative colitis, unspecified	0.030	0.970	0.000
D63.0 Anaemia in neoplastic disease	0.029	0.971	0.000
Q61.2 Polycystic kidney, adult type	0.027	0.972	0.000
Q61.9 Cystic kidney disease, unspecified	0.027	0.973	0.000
K51 Ulcerative colitis	0.027	0.973	0.000
Q61.4 Renal dysplasia	0.025	0.975	0.000
K51.4 Pseudopolyposis of colon	0.025	0.975	0.000
K51.8 Other ulcerative colitis	0.024	0.976	0.000
Q61.8 Other cystic kidney diseases	0.023	0.977	0.000
Q61.1 Polycystic kidney, infantile type	0.023	0.977	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.023	0.977	0.000
K51.2 Ulcerative (chronic) proctitis	0.023	0.977	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.022	0.978	0.000
K51.5 Mucosal proctocolitis	0.020	0.980	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.019	0.981	0.000
S51.0 Open wound of elbow	0.019	0.981	0.000
D03 Melanoma in situ	0.019	0.981	0.000
Q61.5 Medullary cystic kidney	0.018	0.982	0.000
S51 Open wound of forearm	0.017	0.983	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.017	0.983	0.000
S56 Injury of muscle and tendon at forearm level	0.017	0.983	0.000
S50-S59 Injuries to the elbow and forearm	0.017	0.983	0.000
D03.5 Melanoma in situ of trunk	0.016	0.984	0.000
Q60-Q64 Congenital malformations of the urinary system	0.016	0.984	0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.016	0.984	0.000
D03.4 Melanoma in situ of scalp and neck	0.016	0.984	0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.016	0.984	0.000
D03.0 Melanoma in situ of lip	0.015	0.985	0.000
S50 Superficial injury of forearm	0.015	0.985	0.000
S51.8 Open wound of other parts of forearm	0.014	0.986	0.000
S56.7 Injury of multiple muscles and tendons at forearm level	0.014	0.986	0.000
S59 Other and unspecified injuries of forearm	0.014	0.986	0.000
S55 Injury of blood vessels at forearm level	0.014	0.986	0.000
D03.9 Melanoma in situ, unspecified	0.013	0.986	0.000
D03.8 Melanoma in situ of other sites	0.013	0.986	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.013	0.986	0.000
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.013	0.987	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.013	0.987	0.000
S54 Injury of nerves at forearm level	0.013	0.987	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.013	0.987	0.000
S50.0 Contusion of elbow	0.013	0.987	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.012	0.987	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.012	0.987	0.000
S56.2 Injury of other flexor muscle and tendon at forearm level	0.012	0.988	0.000
S56.0 Injury of flexor muscle and tendon of thumb at forearm level	0.012	0.988	0.000
S58 Traumatic amputation of forearm	0.012	0.988	0.000
S57 Crushing injury of forearm	0.012	0.988	0.000
S59.9 Unspecified injury of forearm	0.012	0.988	0.000
S50.9 Superficial injury of forearm, unspecified	0.012	0.988	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.012	0.988	0.000
S50.1 Contusion of other and unspecified parts of forearm	0.012	0.988	0.000
S50.8 Other superficial injuries of forearm	0.012	0.988	0.000
M22.4 Chondromalacia patellae	0.012	0.988	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.012	0.988	0.000
Q27 Other congenital malformations of peripheral vascular system	0.012	0.988	0.000
S50.7 Multiple superficial injuries of forearm	0.012	0.988	0.000
S51.7 Multiple open wounds of forearm	0.011	0.988	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.011	0.989	0.000
S55.0 Injury of ulnar artery at forearm level	0.011	0.989	0.000
D21.0 Connective and other soft tissue of head, face and neck	0.000	0.989	0.011
S56.5 Injury of other extensor muscle and tendon at forearm level	0.011	0.989	0.000
Q39 Congenital malformations of oesophagus	0.011	0.989	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.011	0.989	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.011	0.989	0.000
S51.9 Open wound of forearm, part unspecified	0.011	0.989	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.011	0.989	0.000
Q64 Other congenital malformations of urinary system	0.011	0.989	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.000	0.989	0.011
Q44.6 Cystic disease of liver	0.011	0.989	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.011	0.989	0.000
S55.1 Injury of radial artery at forearm level	0.011	0.989	0.000
Q40 Other congenital malformations of upper alimentary tract	0.010	0.989	0.000
D21.2 Connective and other soft tissue of lower limb, including hip	0.000	0.990	0.010
Q23 Congenital malformations of aortic and mitral valves	0.010	0.990	0.000
S59.8 Other specified injuries of forearm	0.010	0.990	0.000
S59.7 Multiple injuries of forearm	0.010	0.990	0.000
R94.5 Abnormal results of liver function studies	0.010	0.990	0.000
S55.9 Injury of unspecified blood vessel at forearm level	0.010	0.990	0.000
S55.8 Injury of other blood vessels at forearm level	0.010	0.990	0.000
S55.7 Injury of multiple blood vessels at forearm level	0.010	0.990	0.000
S55.2 Injury of vein at forearm level	0.010	0.990	0.000
S54.1 Injury of median nerve at forearm level	0.010	0.990	0.000
K50-K52 Noninfective enteritis and colitis	0.010	0.990	0.000
Q35-Q37 Cleft lip and cleft palate	0.010	0.990	0.000
Q62.5 Duplication of ureter	0.010	0.990	0.000
Q44.7 Other congenital malformations of liver	0.010	0.990	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.010	0.990	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.010	0.990	0.000
Q45 Other congenital malformations of digestive system	0.010	0.990	0.000
S54.0 Injury of ulnar nerve at forearm level	0.009	0.990	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.009	0.990	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.009	0.990	0.000
Q39.4 Oesophageal web	0.009	0.990	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.009	0.990	0.000
D21.9 Connective and other soft tissue, unspecified	0.000	0.990	0.009
Q62.3 Other obstructive defects of renal pelvis and ureter	0.009	0.990	0.000
S54.2 Injury of radial nerve at forearm level	0.009	0.991	0.000
S54.9 Injury of unspecified nerve at forearm level	0.009	0.991	0.000
S54.8 Injury of other nerves at forearm level	0.009	0.991	0.000
S54.7 Injury of multiple nerves at forearm level	0.009	0.991	0.000
S54.3 Injury of cutaneous sensory nerve at forearm level	0.009	0.991	0.000
Z04.9 Examination and observation for unspecified reason	0.009	0.991	0.000
Q28 Other congenital malformations of circulatory system	0.009	0.991	0.000
Q38.6 Other congenital malformations of mouth	0.009	0.991	0.000
Q62.8 Other congenital malformations of ureter	0.009	0.991	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.009	0.991	0.000
Q62.6 Malposition of ureter	0.009	0.991	0.000
Q62.4 Agenesis of ureter	0.009	0.991	0.000
Q62.2 Congenital megaloureter	0.009	0.991	0.000
Q62.1 Atresia and stenosis of ureter	0.009	0.991	0.000
Q62.0 Congenital hydronephrosis	0.009	0.991	0.000
Q30 Congenital malformations of nose	0.009	0.991	0.000
S56.20 Unspecified injury of other flexor muscle, fascia and tendon at forearm level	0.009	0.991	0.000
Q23.1 Congenital insufficiency of aortic valve	0.009	0.991	0.000
Q25 Congenital malformations of great arteries	0.009	0.991	0.000
S57.9 Crushing injury of forearm, part unspecified	0.009	0.991	0.000
S57.8 Crushing injury of forearm, part unspecified	0.009	0.991	0.000
S57.7 Crushing injury of other parts of forearm	0.009	0.991	0.000
S57.0 Crushing injury of elbow	0.009	0.991	0.000
S58.9 Traumatic amputation of forearm, level unspecified	0.009	0.991	0.000
S58.1 Traumatic amputation at level between elbow and wrist	0.009	0.991	0.000
S58.0 Traumatic amputation at elbow level	0.009	0.991	0.000
D21.5 Connective and other soft tissue of pelvis	0.000	0.991	0.009
D21.4 Connective and other soft tissue of abdomen	0.000	0.991	0.009
S52 Fracture of forearm	0.009	0.991	0.000
Q27.3 Peripheral arteriovenous malformation	0.009	0.991	0.000
Q63 Other congenital malformations of kidney	0.009	0.991	0.000
Q44.4 Choledochal cyst	0.009	0.991	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.009	0.991	0.000
Q44.2 Atresia of bile ducts	0.009	0.991	0.000
Q44.1 Other congenital malformations of gallbladder	0.009	0.991	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.009	0.991	0.000
Q80-Q89 Other congenital malformations	0.009	0.991	0.000
Q44.5 Other congenital malformations of bile ducts	0.009	0.991	0.000
Q26 Congenital malformations of great veins	0.009	0.991	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.009	0.991	0.000
Q27.4 Congenital phlebectasia	0.008	0.991	0.000
Q27.2 Other congenital malformations of renal artery	0.008	0.991	0.000
Q27.1 Congenital renal artery stenosis	0.008	0.991	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.008	0.991	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.009	0.991	0.000
Q23.0 Congenital stenosis of aortic valve	0.008	0.991	0.000
Q31 Congenital malformations of larynx	0.008	0.991	0.000
Q38.1 Ankyloglossia	0.008	0.992	0.000
S52.6 Fracture of lower end of both ulna and radius	0.008	0.992	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.008	0.992	0.000
S53.0 Dislocation of radial head	0.008	0.992	0.000
Q43 Other congenital malformations of intestine	0.008	0.992	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations