TreeWAS – Variant ID: rs3783890

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S01 Open wound of head	0.445	0.555	0.000
S01.5 Open wound of lip and oral cavity	0.438	0.562	0.000
S01.3 Open wound of ear	0.435	0.565	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.427	0.573	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.423	0.577	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.420	0.580	0.000
S00-S09 Injuries to the head	0.418	0.582	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.413	0.587	0.000
S60-S69 Injuries to the wrist and hand	0.402	0.598	0.000
S90-S99 Injuries to the ankle and foot	0.399	0.601	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.390	0.610	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.383	0.617	0.000
T36 Poisoning by systemic antibiotics	0.380	0.620	0.000
S90 Superficial injury of ankle and foot	0.378	0.622	0.000
S67 Crushing injury of wrist and hand	0.376	0.624	0.000
S01.0 Open wound of scalp	0.375	0.625	0.000
S10-S19 Injuries to the neck	0.371	0.629	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.371	0.629	0.000
I10 Essential (primary) hypertension	0.000	0.633	0.367
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.364	0.636	0.000
S06 Intracranial injury	0.363	0.637	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.362	0.638	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.354	0.646	0.000
S63.6 Sprain and strain of finger(s)	0.354	0.646	0.000
S68 Traumatic amputation of wrist and hand	0.351	0.649	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.349	0.651	0.000
T00-T07 Injuries involving multiple body regions	0.347	0.653	0.000
S00 Superficial injury of head	0.347	0.653	0.000
T79-T79 Certain early complications of trauma	0.346	0.654	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.346	0.654	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.346	0.654	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.344	0.656	0.000
S01.7 Multiple open wounds of head	0.340	0.660	0.000
T42.1 Iminostilbenes	0.340	0.660	0.000
S99 Other and unspecified injuries of ankle and foot	0.339	0.661	0.000
S01.4 Open wound of cheek and temporomandibular area	0.339	0.661	0.000
T36.0 Penicillins	0.338	0.662	0.000
T21 Burn and corrosion of trunk	0.334	0.666	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.334	0.666	0.000
S01.2 Open wound of nose	0.333	0.667	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.333	0.667	0.000
S00.3 Superficial injury of nose	0.332	0.668	0.000
T42.0 Hydantoin derivatives	0.331	0.669	0.000
S69 Other and unspecified injuries of wrist and hand	0.330	0.670	0.000
S92 Fracture of foot, except ankle	0.325	0.675	0.000
S06.2 Diffuse brain injury	0.324	0.676	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.323	0.677	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.320	0.680	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.320	0.680	0.000
S60 Superficial injury of wrist and hand	0.318	0.682	0.000
S90.3 Contusion of other and unspecified parts of foot	0.317	0.683	0.000
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.316	0.684	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.315	0.685	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.313	0.687	0.000
S01.9 Open wound of head, part unspecified	0.311	0.689	0.000
S01.1 Open wound of eyelid and periocular area	0.311	0.689	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.310	0.690	0.000
S13.4 Sprain and strain of cervical spine	0.309	0.691	0.000
S00.1 Contusion of eyelid and periocular area	0.309	0.691	0.000
T23 Burn and corrosion of wrist and hand	0.309	0.691	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.307	0.693	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.306	0.694	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.306	0.694	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.306	0.694	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.305	0.695	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.303	0.697	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.303	0.697	0.000
T42.3 Barbiturates	0.303	0.697	0.000
T42.2 Succinimides and oxazolidinediones	0.303	0.697	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.301	0.699	0.000
S08 Traumatic amputation of part of head	0.299	0.700	0.000
S07 Crushing injury of head	0.299	0.700	0.000
S04 Injury of cranial nerves	0.299	0.700	0.000
S06.3 Focal brain injury	0.299	0.701	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.299	0.701	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.298	0.702	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.298	0.702	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.297	0.702	0.000
S00.7 Multiple superficial injuries of head	0.297	0.703	0.000
T33-T35 Frostbite	0.296	0.704	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.296	0.704	0.000
S01.8 Open wound of other parts of head	0.296	0.704	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.296	0.704	0.000
T21.3 Burn of third degree of trunk	0.296	0.704	0.000
T39.1 4-Aminophenol derivatives	0.294	0.706	0.000
T36.3 Macrolides	0.294	0.706	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.294	0.706	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.293	0.707	0.000
S99.9 Unspecified injury of ankle and foot	0.291	0.709	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.289	0.711	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.288	0.712	0.000
S63.0 Dislocation of wrist	0.287	0.713	0.000
S98 Traumatic amputation of ankle and foot	0.286	0.713	0.000
S97 Crushing injury of ankle and foot	0.286	0.713	0.000
S95 Injury of blood vessels at ankle and foot level	0.286	0.713	0.000
S94 Injury of nerves at ankle and foot level	0.286	0.713	0.000
S10 Superficial injury of neck	0.286	0.714	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.285	0.715	0.000
S90.8 Other superficial injuries of ankle and foot	0.285	0.715	0.000
T01 Open wounds involving multiple body regions	0.285	0.715	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.283	0.717	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.283	0.717	0.000
S14 Injury of nerves and spinal cord at neck level	0.283	0.717	0.000
S13.1 Dislocation of cervical vertebra	0.283	0.717	0.000
S69.9 Unspecified injury of wrist and hand	0.281	0.719	0.000
T25 Burn and corrosion of ankle and foot	0.280	0.719	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.280	0.720	0.000
S63.1 Dislocation finger	0.279	0.721	0.000
S63.2 Multiple dislocations of fingers	0.279	0.721	0.000
S92.4 Fracture of great toe	0.279	0.721	0.000
T43.6 Psychostimulants with abuse potential	0.277	0.723	0.000
T39.0 Salicylates	0.275	0.725	0.000
S92.3 Fracture of metatarsal bone	0.275	0.725	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.274	0.726	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.273	0.726	0.000
S06.1 Traumatic cerebral oedema	0.273	0.727	0.000
S60.2 Contusion of other parts of wrist and hand	0.273	0.727	0.000
T21.2 Burn of second degree of trunk	0.273	0.727	0.000
T36.9 Systemic antibiotic, unspecified	0.273	0.727	0.000
T36.8 Other systemic antibiotics	0.273	0.727	0.000
T36.7 Antifungal antibiotics, systemically used	0.273	0.727	0.000
T36.6 Rifamycins	0.273	0.727	0.000
T36.5 Aminoglycosides	0.273	0.727	0.000
T36.4 Tetracyclines	0.273	0.727	0.000
T36.2 Chloramphenicol group	0.273	0.727	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.273	0.727	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.271	0.729	0.000
S90.2 Contusion of toe(s) with damage to nail	0.271	0.729	0.000
S90.1 Contusion of toe(s) without damage to nail	0.271	0.729	0.000
T14 Injury of unspecified body region	0.270	0.730	0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.269	0.731	0.000
T09 Other injuries of spine and trunk, level unspecified	0.268	0.732	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.267	0.733	0.000
T00 Superficial injuries involving multiple body regions	0.267	0.733	0.000
S17 Crushing injury of neck	0.266	0.734	0.000
S15 Injury of blood vessels at neck level	0.266	0.734	0.000
S18 Traumatic amputation at neck level	0.266	0.734	0.000
S16 Injury of muscle and tendon at neck level	0.266	0.734	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.266	0.734	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.266	0.734	0.000
T46.7 Peripheral vasodilators	0.266	0.734	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.266	0.734	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.266	0.734	0.000
T63 Toxic effect of contact with venomous animals	0.265	0.735	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.264	0.735	0.000
T23.3 Burn of third degree of wrist and hand	0.264	0.736	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.263	0.737	0.000
S11 Open wound of neck	0.263	0.737	0.000
T43.2 Other and unspecified antidepressants	0.262	0.738	0.000
T43.9 Psychotropic drug, unspecified	0.261	0.739	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.261	0.739	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.261	0.739	0.000
S06.7 Intracranial injury with prolonged coma	0.260	0.740	0.000
T39.4 Antirheumatics, not elsewhere classified	0.259	0.740	0.000
T39.2 Pyrazolone derivatives	0.259	0.740	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.259	0.741	0.000
S06.5 Traumatic subdural haemorrhage	0.259	0.741	0.000
T46.1 Calcium-channel blockers	0.258	0.742	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.258	0.742	0.000
S90.0 Contusion of ankle	0.257	0.743	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.257	0.743	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.256	0.743	0.000
T02 Fractures involving multiple body regions	0.256	0.744	0.000
T42.4 Benzodiazepines	0.253	0.747	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.253	0.747	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.253	0.747	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.252	0.747	0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.252	0.748	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.252	0.748	0.000
S68.4 Traumatic amputation of hand at wrist level	0.252	0.748	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.252	0.748	0.000
S99.8 Other specified injuries of ankle and foot	0.252	0.748	0.000
T38.1 Thyroid hormones and substitutes	0.251	0.749	0.000
S65 Injury of blood vessels at wrist and hand level	0.250	0.749	0.000
S12 Fracture of neck	0.250	0.750	0.000
S69.8 Other specified injuries of wrist and hand	0.250	0.750	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.249	0.751	0.000
T05 Traumatic amputations involving multiple body regions	0.249	0.751	0.000
T04 Crushing injuries involving multiple body regions	0.249	0.751	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.249	0.751	0.000
T07 Unspecified multiple injuries	0.249	0.751	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.249	0.751	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.248	0.751	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.248	0.752	0.000
S13.5 Sprain and strain of thyroid region	0.248	0.752	0.000
S13.3 Multiple dislocations of neck	0.248	0.752	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.248	0.752	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.248	0.752	0.000
T38.9 Other and unspecified hormone antagonists	0.248	0.752	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.248	0.752	0.000
T38.7 Androgens and anabolic congeners	0.248	0.752	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.248	0.752	0.000
T38.5 Other oestrogens and progestogens	0.248	0.752	0.000
T38.4 Oral contraceptives	0.248	0.752	0.000
T38.2 Antithyroid drugs	0.248	0.752	0.000
T38.0 Glucocorticoids and synthetic analogues	0.248	0.752	0.000
S92.0 Fracture of calcaneus	0.248	0.752	0.000
S92.41 Fracture of great toe (open)	0.247	0.753	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.246	0.753	0.000
T59 Toxic effect of other gases, fumes and vapours	0.246	0.754	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.246	0.754	0.000
S06.0 Concussion	0.246	0.754	0.000
T56 Toxic effect of metals	0.244	0.756	0.000
S60.8 Other superficial injuries of wrist and hand	0.244	0.756	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.244	0.756	0.000
S99.7 Multiple injuries of ankle and foot	0.243	0.757	0.000
T20 Burn and corrosion of head and neck	0.243	0.757	0.000
T01.2 Open wounds involving multiple regions of upper limb(s)	0.240	0.760	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.240	0.760	0.000
T21.7 Corrosion of third degree of trunk	0.239	0.761	0.000
T21.6 Corrosion of second degree of trunk	0.239	0.761	0.000
T21.5 Corrosion of first degree of trunk	0.239	0.761	0.000
T21.4 Corrosion of unspecified degree of trunk	0.239	0.761	0.000
T21.1 Burn of first degree of trunk	0.239	0.761	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.239	0.761	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.239	0.761	0.000
T12 Fracture of lower limb, level unspecified	0.239	0.761	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.239	0.761	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.239	0.761	0.000
T10 Fracture of upper limb, level unspecified	0.239	0.761	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.239	0.761	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.239	0.761	0.000
T08 Fracture of spine, level unspecified	0.239	0.761	0.000
S92.30 Fracture of metatarsal bone (closed)	0.238	0.762	0.000
S91 Open wound of ankle and foot	0.236	0.764	0.000
T23.1 Burn of first degree of wrist and hand	0.235	0.765	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.234	0.766	0.000
S92.9 Fracture of foot, unspecified	0.233	0.766	0.000
T14.1 Open wound of unspecified body region	0.233	0.767	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.232	0.768	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.232	0.768	0.000
T48.5 Anti-common-cold drugs	0.232	0.768	0.000
T48.4 Expectorants	0.232	0.768	0.000
T48.3 Antitussives	0.232	0.768	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.232	0.768	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.232	0.768	0.000
T48.0 Oxytocic drugs	0.232	0.768	0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.232	0.768	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.231	0.769	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.229	0.770	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.229	0.770	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.229	0.770	0.000
T65 Toxic effect of other and unspecified substances	0.229	0.771	0.000
T62 Toxic effect of other noxious substances eaten as food	0.229	0.771	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.229	0.771	0.000
T60 Toxic effect of pesticides	0.229	0.771	0.000
T57 Toxic effect of other inorganic substances	0.229	0.771	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.229	0.771	0.000
T52 Toxic effect of organic solvents	0.229	0.771	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.229	0.771	0.000
T55 Toxic effect of soaps and detergents	0.229	0.771	0.000
S92.7 Multiple fractures of foot	0.228	0.771	0.000
T11 Other injuries of upper limb, level unspecified	0.228	0.772	0.000
S60.1 Contusion of finger(s) with damage to nail	0.228	0.772	0.000
T54 Toxic effect of corrosive substances	0.227	0.773	0.000
S06.4 Epidural haemorrhage	0.227	0.773	0.000
T47.4 Other laxatives	0.226	0.773	0.000
T63.4 Venom of other arthropods	0.226	0.774	0.000
T79.8 Other early complications of trauma	0.226	0.774	0.000
T13 Other injuries of lower limb, level unspecified	0.225	0.775	0.000
S06.9 Intracranial injury, unspecified	0.224	0.775	0.000
S19 Other and unspecified injuries of neck	0.223	0.777	0.000
S92.5 Fracture of other toe	0.222	0.778	0.000
T23.7 Corrosion of third degree of wrist and hand	0.222	0.778	0.000
T23.6 Corrosion of second degree of wrist and hand	0.222	0.778	0.000
T23.5 Corrosion of first degree of wrist and hand	0.222	0.778	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.222	0.778	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.220	0.780	0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.220	0.780	0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.220	0.780	0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.220	0.780	0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.220	0.780	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.220	0.780	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.220	0.780	0.000
T37.5 Antiviral drugs	0.220	0.780	0.000
T37.4 Anthelminthics	0.220	0.780	0.000
T37.3 Other antiprotozoal drugs	0.220	0.780	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.220	0.780	0.000
T37.1 Antimycobacterial drugs	0.220	0.780	0.000
T37.0 Sulphonamides	0.220	0.780	0.000
T41.5 Therapeutic gases	0.220	0.780	0.000
T41.4 Anaesthetic, unspecified	0.220	0.780	0.000
T41.3 Local anaesthetics	0.220	0.780	0.000
T41.2 Other and unspecified general anaesthetics	0.220	0.780	0.000
T41.1 Intravenous anaesthetics	0.220	0.780	0.000
T41.0 Inhaled anaesthetics	0.220	0.780	0.000
T49.9 Topical agent, unspecified	0.220	0.780	0.000
T49.8 Other topical agents	0.220	0.780	0.000
T49.7 Dental drugs, topically applied	0.220	0.780	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.220	0.780	0.000
T49.5 Ophthalmological drugs and preparations	0.220	0.780	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.220	0.780	0.000
T49.3 Emollients, demulcents and protectants	0.220	0.780	0.000
T49.2 Local astringents and local detergents	0.220	0.780	0.000
T49.1 Antipruritics	0.220	0.780	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.220	0.780	0.000
S10.9 Superficial injury of neck, part unspecified	0.219	0.781	0.000
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.219	0.781	0.000
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.219	0.781	0.000
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.219	0.781	0.000
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.219	0.781	0.000
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.219	0.781	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.218	0.782	0.000
S69.7 Multiple injuries of wrist and hand	0.217	0.783	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.216	0.784	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.216	0.784	0.000
S05 Injury of eye and orbit	0.216	0.784	0.000
S06.8 Other intracranial injuries	0.215	0.785	0.000
S04.9 Injury of unspecified cranial nerve	0.215	0.785	0.000
S04.8 Injury of other cranial nerves	0.215	0.785	0.000
S04.7 Injury of accessory nerve	0.215	0.785	0.000
S04.6 Injury of acoustic nerve	0.215	0.785	0.000
S04.5 Injury of facial nerve	0.215	0.785	0.000
S04.4 Injury of abducent nerve	0.215	0.785	0.000
S04.3 Injury of trigeminal nerve	0.215	0.785	0.000
S04.2 Injury of trochlear nerve	0.215	0.785	0.000
S04.1 Injury of oculomotor nerve	0.215	0.785	0.000
S04.0 Injury of optic nerve and pathways	0.215	0.785	0.000
S07.9 Crushing injury of head, part unspecified	0.215	0.785	0.000
S07.8 Crushing injury of other parts of head	0.215	0.785	0.000
S07.1 Crushing injury of skull	0.215	0.785	0.000
S07.0 Crushing injury of face	0.215	0.785	0.000
S08.9 Traumatic amputation of unspecified part of head	0.215	0.785	0.000
S08.8 Traumatic amputation of other parts of head	0.215	0.785	0.000
S08.1 Traumatic amputation of ear	0.215	0.785	0.000
S08.0 Avulsion of scalp	0.215	0.785	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.215	0.785	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.214	0.786	0.000
T79.9 Unspecified early complication of trauma	0.214	0.786	0.000
T79.5 Traumatic anuria	0.214	0.786	0.000
T79.4 Traumatic shock	0.214	0.786	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.214	0.786	0.000
T79.1 Fat embolism (traumatic)	0.214	0.786	0.000
T79.0 Air embolism (traumatic)	0.214	0.786	0.000
T28 Burn and corrosion of other internal organs	0.212	0.787	0.000
T27 Burn and corrosion of respiratory tract	0.212	0.787	0.000
T26 Burn and corrosion confined to eye and adnexa	0.212	0.787	0.000
T35 Frostbite involving multiple body regions and unspecified frostbite	0.212	0.787	0.000
T34 Frostbite with tissue necrosis	0.212	0.787	0.000
T33 Superficial frostbite	0.212	0.787	0.000
S10.8 Superficial injury of other parts of neck	0.212	0.787	0.000
S61 Open wound of wrist and hand	0.212	0.788	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.211	0.789	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.211	0.789	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.211	0.789	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.211	0.789	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.211	0.789	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.211	0.789	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.211	0.789	0.000
T44.0 Anticholinesterase agents	0.211	0.789	0.000
S64 Injury of nerves at wrist and hand level	0.211	0.789	0.000
T58 Toxic effect of carbon monoxide	0.209	0.791	0.000
T40.2 Other opioids	0.209	0.791	0.000
T09.9 Unspecified injury of trunk, level unspecified	0.209	0.791	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.208	0.791	0.000
T23.2 Burn of second degree of wrist and hand	0.208	0.792	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.207	0.793	0.000
S03.4 Sprain and strain of jaw	0.207	0.793	0.000
S03.3 Dislocation of other and unspecified parts of head	0.207	0.793	0.000
S03.1 Dislocation of septal cartilage of nose	0.207	0.793	0.000
S03.0 Dislocation of jaw	0.207	0.793	0.000
T25.3 Burn of third degree of ankle and foot	0.207	0.793	0.000
T09.0 Superficial injury of trunk, level unspecified	0.207	0.793	0.000
S00.9 Superficial injury of head, part unspecified	0.206	0.794	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.205	0.794	0.000
S94.8 Injury of other nerves at ankle and foot level	0.205	0.794	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.205	0.794	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.205	0.794	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.205	0.794	0.000
S94.1 Injury of medial plantar nerve	0.205	0.794	0.000
S94.0 Injury of lateral plantar nerve	0.205	0.794	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.205	0.794	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.205	0.794	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.205	0.794	0.000
S95.2 Injury of dorsal vein of foot	0.205	0.794	0.000
S95.1 Injury of plantar artery of foot	0.205	0.794	0.000
S95.0 Injury of dorsal artery of foot	0.205	0.794	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.205	0.794	0.000
S97.1 Crushing injury of toe(s)	0.205	0.794	0.000
S97.0 Crushing injury of ankle	0.205	0.794	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.205	0.794	0.000
S98.3 Traumatic amputation of other parts of foot	0.205	0.794	0.000
S98.2 Traumatic amputation of two or more toes	0.205	0.794	0.000
S98.1 Traumatic amputation of one toe	0.205	0.794	0.000
S98.0 Traumatic amputation of foot at ankle level	0.205	0.794	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.205	0.794	0.000
S10.7 Multiple superficial injuries of neck	0.205	0.795	0.000
S10.1 Other and unspecified superficial injuries of throat	0.205	0.795	0.000
S10.0 Contusion of throat	0.205	0.795	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.205	0.795	0.000
S14.3 Injury of brachial plexus	0.204	0.796	0.000
T01.9 Multiple open wounds, unspecified	0.204	0.796	0.000
T01.8 Open wounds involving other combinations of body regions	0.204	0.796	0.000
T01.6 Open wounds involving multiple regions of upper limb(s) with lower limb(s)	0.204	0.796	0.000
T01.3 Open wounds involving multiple regions of lower limb(s)	0.204	0.796	0.000
T01.1 Open wounds involving thorax with abdomen, lower back and pelvis	0.204	0.796	0.000
T01.0 Open wounds involving head with neck	0.204	0.796	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.203	0.797	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.203	0.797	0.000
T47.7 Emetics	0.203	0.797	0.000
T47.6 Antidiarrhoeal drugs	0.203	0.797	0.000
T47.5 Digestants	0.203	0.797	0.000
T47.3 Saline and osmotic laxatives	0.203	0.797	0.000
T47.2 Stimulant laxatives	0.203	0.797	0.000
T47.0 Histamine H(2)-receptor antagonists	0.203	0.797	0.000
S14.6 Injury of other and unspecified nerves of neck	0.203	0.797	0.000
S14.5 Injury of cervical sympathetic nerves	0.203	0.797	0.000
S14.4 Injury of peripheral nerves of neck	0.203	0.797	0.000
S14.2 Injury of nerve root of cervical spine	0.203	0.797	0.000
S14.0 Concussion and oedema of cervical spinal cord	0.203	0.797	0.000
S91.1 Open wound of toe(s) without damage to nail	0.201	0.798	0.000
T00.9 Multiple superficial injuries, unspecified	0.201	0.798	0.000
S11.7 Multiple open wounds of neck	0.201	0.799	0.000
T25.7 Corrosion of third degree of ankle and foot	0.201	0.799	0.000
T25.6 Corrosion of second degree of ankle and foot	0.201	0.799	0.000
T25.5 Corrosion of first degree of ankle and foot	0.201	0.799	0.000
T25.4 Corrosion of unspecified degree of ankle and foot	0.201	0.799	0.000
T25.2 Burn of second degree of ankle and foot	0.201	0.799	0.000
T25.1 Burn of first degree of ankle and foot	0.201	0.799	0.000
T25.0 Burn of unspecified degree of ankle and foot	0.201	0.799	0.000
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.200	0.799	0.000
T00.3 Superficial injuries involving multiple regions of lower limb(s)	0.200	0.800	0.000
S00.4 Superficial injury of ear	0.199	0.801	0.000
T21.0 Burn of unspecified degree of trunk	0.198	0.802	0.000
S63.5 Sprain and strain of wrist	0.197	0.802	0.000
S93.0 Dislocation of ankle joint	0.197	0.803	0.000
S92.31 Fracture of metatarsal bone (open)	0.197	0.803	0.000
S03.2 Dislocation of tooth	0.197	0.803	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.196	0.804	0.000
S92.40 Fracture of great toe (closed)	0.196	0.804	0.000
S92.2 Fracture of other tarsal bone(s)	0.195	0.804	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.195	0.804	0.000
T79.7 Traumatic subcutaneous emphysema	0.195	0.805	0.000
T50.4 Drugs affecting uric acid metabolism	0.195	0.805	0.000
T14.2 Fracture of unspecified body region	0.194	0.806	0.000
T14.9 Injury, unspecified	0.194	0.806	0.000
T14.8 Other injuries of unspecified body region	0.194	0.806	0.000
T14.7 Crushing injury and traumatic amputation of unspecified body region	0.194	0.806	0.000
T14.6 Injury of tendons and muscles of unspecified body region	0.194	0.806	0.000
T14.5 Injury of blood vessel(s) of unspecified body region	0.194	0.806	0.000
T14.4 Injury of nerve(s) of unspecified body region	0.194	0.806	0.000
T14.3 Dislocation, sprain and strain of unspecified body region	0.194	0.806	0.000
T59.8 Other specified gases, fumes and vapours	0.193	0.807	0.000
T20.3 Burn of third degree of head and neck	0.193	0.807	0.000
S00.5 Superficial injury of lip and oral cavity	0.193	0.807	0.000
S92.00 Fracture of calcaneus (closed)	0.192	0.808	0.000
T09.8 Other specified injuries of trunk, level unspecified	0.192	0.808	0.000
T09.6 Traumatic amputation of trunk, level unspecified	0.192	0.808	0.000
T09.5 Injury of unspecified muscle and tendon of trunk	0.192	0.808	0.000
T09.4 Injury of unspecified nerve, spinal nerve root and plexus of trunk	0.192	0.808	0.000
T09.3 Injury of spinal cord, level unspecified	0.192	0.808	0.000
T09.2 Dislocation, strain and sprain of unspecified joint and ligament of trunk	0.192	0.808	0.000
T09.1 Open wound of trunk, level unspecified	0.192	0.808	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.192	0.808	0.000
T00.8 Superficial injuries involving other combinations of body regions	0.191	0.809	0.000
T00.6 Superficial injuries involving multiple regions of upper limb(s) with lower limb(s)	0.191	0.809	0.000
T00.2 Superficial injuries involving multiple regions of upper limb(s)	0.191	0.809	0.000
T00.1 Superficial injuries involving thorax with abdomen, lower back and pelvis	0.191	0.809	0.000
T00.0 Superficial injuries involving head with neck	0.191	0.809	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.191	0.809	0.000
S15.9 Injury of unspecified blood vessel at neck level	0.191	0.809	0.000
S15.8 Injury of other blood vessels at neck level	0.191	0.809	0.000
S15.7 Injury of multiple blood vessels at neck level	0.191	0.809	0.000
S15.3 Injury of internal jugular vein	0.191	0.809	0.000
S15.2 Injury of external jugular vein	0.191	0.809	0.000
S15.1 Injury of vertebral artery	0.191	0.809	0.000
S15.0 Injury of carotid artery	0.191	0.809	0.000
S17.9 Crushing injury of neck, part unspecified	0.191	0.809	0.000
S17.8 Crushing injury of other parts of neck	0.191	0.809	0.000
S17.0 Crushing injury of larynx and traches	0.191	0.809	0.000
S92.1 Fracture of talus	0.191	0.809	0.000
S12.1 Fracture of second cervical vertebra	0.191	0.809	0.000
T63.9 Toxic effect of contact with unspecified venomous animal	0.190	0.810	0.000
T63.8 Toxic effect of contact with other venomous animals	0.190	0.810	0.000
T63.6 Toxic effect of contact with other marine animals	0.190	0.810	0.000
T63.5 Toxic effect of contact with fish	0.190	0.810	0.000
T63.3 Venom of spider	0.190	0.810	0.000
T63.2 Venom of scorpion	0.190	0.810	0.000
T63.1 Venom of other reptiles	0.190	0.810	0.000
T63.0 Snake venom	0.190	0.810	0.000
T56.8 Other metals	0.190	0.810	0.000
S60.0 Contusion of finger(s) without damage to nail	0.190	0.810	0.000
T32 Corrosions classified according to extent of body surface involved	0.190	0.810	0.000
T30 Burn and corrosion, body region unspecified	0.190	0.810	0.000
T29 Burns and corrosions of multiple body regions	0.190	0.810	0.000
T51 Toxic effect of alcohol	0.189	0.811	0.000
T50.8 Diagnostic agents	0.189	0.811	0.000
T50.7 Analeptics and opioid receptor antagonists	0.189	0.811	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.189	0.811	0.000
T50.5 Appetite depressants	0.189	0.811	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.189	0.811	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.189	0.811	0.000
T50.1 Loop [high-ceiling] diuretics	0.189	0.811	0.000
T50.0 Mineralocorticoids and their antagonists	0.189	0.811	0.000
S11.8 Open wound of other parts of neck	0.189	0.811	0.000
S11.2 Open wound involving pharynx and cervical oesophagus	0.189	0.811	0.000
S11.1 Open wound involving thyroid gland	0.189	0.811	0.000
S11.0 Open wound involving larynx and trachea	0.189	0.811	0.000
T79.6 Traumatic ischaemia of muscle	0.189	0.811	0.000
T02.5 Fractures involving multiple regions of both lower limbs	0.188	0.812	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations