TreeWAS – Variant ID: rs3785176

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H18.5 Hereditary corneal dystrophies	0.085	0.915	0.000
H18 Other disorders of cornea	0.066	0.934	0.000
H18.2 Other corneal oedema	0.056	0.944	0.000
H18.8 Other specified disorders of cornea	0.054	0.946	0.000
H18.9 Disorder of cornea, unspecified	0.050	0.950	0.000
H18.4 Corneal degeneration	0.050	0.950	0.000
H18.0 Corneal pigmentations and deposits	0.049	0.951	0.000
H18.3 Changes in corneal membranes	0.048	0.952	0.000
H18.7 Other corneal deformities	0.047	0.952	0.000
H18.1 Bullous keratopathy	0.047	0.953	0.000
D41.4 Bladder	0.041	0.959	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.036	0.964	0.000
H18.6 Keratoconus	0.030	0.970	0.000
G30.9 Alzheimer's disease, unspecified	0.028	0.972	0.000
H15 Disorders of sclera	0.028	0.972	0.000
H21 Other disorders of iris and ciliary body	0.027	0.973	0.000
H20 Iridocyclitis	0.027	0.973	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.027	0.973	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.027	0.973	0.000
H17 Corneal scars and opacities	0.026	0.974	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.026	0.974	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.023	0.977	0.000
H20.0 Acute and subacute iridocyclitis	0.023	0.977	0.000
H21.8 Other specified disorders of iris and ciliary body	0.023	0.977	0.000
H15.8 Other disorders of sclera	0.023	0.977	0.000
H16 Keratitis	0.022	0.978	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.022	0.978	0.000
T40.2 Other opioids	0.022	0.978	0.000
N99.0 Postprocedural renal failure	0.022	0.978	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.021	0.979	0.000
H21.4 Pupillary membranes	0.021	0.979	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.021	0.979	0.000
E10 Insulin-dependent diabetes mellitus	0.021	0.979	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.021	0.979	0.000
G30 Alzheimer's disease	0.021	0.979	0.000
E10.5 With peripheral circulatory complications	0.020	0.980	0.000
H15.9 Disorder of sclera, unspecified	0.020	0.980	0.000
H20.1 Chronic iridocyclitis	0.020	0.980	0.000
H15.0 Scleritis	0.020	0.980	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.020	0.980	0.000
H17.9 Corneal scar and opacity, unspecified	0.020	0.980	0.000
E10.6 With other specified complications	0.020	0.980	0.000
H20.2 Lens-induced iridocyclitis	0.020	0.980	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.019	0.980	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.019	0.980	0.000
H15.1 Episcleritis	0.019	0.980	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.019	0.980	0.000
N99.2 Postprocedural adhesions of vagina	0.019	0.981	0.000
H17.1 Other central corneal opacity	0.019	0.981	0.000
H17.0 Adherent leukoma	0.019	0.981	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.019	0.981	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.019	0.981	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.019	0.981	0.000
T40.4 Other synthetic narcotics	0.019	0.981	0.000
E10.3 With ophthalmic complications	0.019	0.981	0.000
H20.8 Other iridocyclitis	0.019	0.981	0.000
H21.0 Hyphaema	0.019	0.981	0.000
H17.8 Other corneal scars and opacities	0.019	0.981	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.019	0.981	0.000
E10.2 With renal complications	0.019	0.981	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.018	0.982	0.000
N99.5 Malfunction of external stoma of urinary tract	0.018	0.982	0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.018	0.982	0.000
T40.6 Other and unspecified narcotics	0.018	0.982	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.982	0.018
H21.2 Degeneration of iris and ciliary body	0.017	0.982	0.000
H16.2 Keratoconjunctivitis	0.017	0.983	0.000
G30.0 Alzheimer's disease with early onset	0.017	0.983	0.000
H16.8 Other keratitis	0.017	0.983	0.000
T40.1 Heroin	0.017	0.983	0.000
N99.1 Postprocedural urethral stricture	0.017	0.983	0.000
G30.8 Other Alzheimer's disease	0.017	0.983	0.000
T40.5 Cocaine	0.017	0.983	0.000
H20.9 Iridocyclitis, unspecified	0.017	0.983	0.000
E10.0 With coma	0.016	0.984	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.016	0.984	0.000
H16.3 Interstitial and deep keratitis	0.016	0.984	0.000
H16.4 Corneal neovascularisation	0.016	0.984	0.000
E10.8 With unspecified complications	0.016	0.984	0.000
G30.1 Alzheimer's disease with late onset	0.015	0.984	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.015	0.985	0.000
T40.8 Lysergide [LSD]	0.015	0.985	0.000
T40.7 Cannabis (derivatives)	0.015	0.985	0.000
T40.3 Methadone	0.015	0.985	0.000
T40.0 Opium	0.015	0.985	0.000
E10.7 With multiple complications	0.015	0.985	0.000
E10.4 With neurological complications	0.015	0.985	0.000
E10.1 With ketoacidosis	0.015	0.985	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.015	0.985	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.015	0.985	0.000
H16.0 Corneal ulcer	0.015	0.985	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.014	0.986	0.000
E10.9 Without complications	0.014	0.986	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.013	0.987	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.013	0.987	0.000
H16.9 Keratitis, unspecified	0.012	0.987	0.000
D41.1 Renal pelvis	0.012	0.987	0.000
D41.2 Ureter	0.012	0.988	0.000
D41.9 Urinary organ, unspecified	0.012	0.988	0.000
D41.7 Other urinary organs	0.012	0.988	0.000
D41.3 Urethra	0.012	0.988	0.000
T36 Poisoning by systemic antibiotics	0.012	0.988	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.012	0.988	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.011	0.989	0.000
T36.0 Penicillins	0.011	0.989	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.010	0.989	0.000
M19.92 Arthrosis, unspecified (Upper arm)	0.010	0.990	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.010	0.990	0.000
T46.1 Calcium-channel blockers	0.010	0.990	0.000
D41.0 Kidney	0.010	0.990	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.010	0.990	0.000
N99-N99 Other disorders of the genitourinary system	0.010	0.990	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.009	0.990	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.009	0.991	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.009	0.991	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.009	0.991	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.009	0.991	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.009	0.991	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.009	0.991	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.009	0.991	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.009	0.991	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.009	0.991	0.000
T38.1 Thyroid hormones and substitutes	0.009	0.991	0.000
T36.9 Systemic antibiotic, unspecified	0.008	0.991	0.000
T36.8 Other systemic antibiotics	0.008	0.991	0.000
T36.7 Antifungal antibiotics, systemically used	0.008	0.991	0.000
T36.6 Rifamycins	0.008	0.991	0.000
T36.5 Aminoglycosides	0.008	0.991	0.000
T36.4 Tetracyclines	0.008	0.991	0.000
T36.3 Macrolides	0.008	0.991	0.000
T36.2 Chloramphenicol group	0.008	0.991	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.008	0.991	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.008	0.991	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.008	0.991	0.000
T46.7 Peripheral vasodilators	0.008	0.991	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.008	0.991	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.008	0.991	0.000
T45.0 Antiallergic and antiemetic drugs	0.009	0.991	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.008	0.992	0.000
X41.9 Unspecified place	0.008	0.992	0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.008	0.992	0.000
T38.9 Other and unspecified hormone antagonists	0.008	0.992	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.008	0.992	0.000
T38.7 Androgens and anabolic congeners	0.008	0.992	0.000
T38.5 Other oestrogens and progestogens	0.008	0.992	0.000
T38.4 Oral contraceptives	0.008	0.992	0.000
T38.2 Antithyroid drugs	0.008	0.992	0.000
T38.0 Glucocorticoids and synthetic analogues	0.008	0.992	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.008	0.992	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.008	0.992	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.008	0.992	0.000
T37.5 Antiviral drugs	0.008	0.992	0.000
T37.4 Anthelminthics	0.008	0.992	0.000
T37.3 Other antiprotozoal drugs	0.008	0.992	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.008	0.992	0.000
T37.1 Antimycobacterial drugs	0.008	0.992	0.000
T37.0 Sulphonamides	0.008	0.992	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.008	0.992	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.008	0.992	0.000
G30-G32 Other degenerative diseases of the nervous system	0.008	0.992	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.007	0.993	0.000
T49.9 Topical agent, unspecified	0.007	0.993	0.000
T49.8 Other topical agents	0.007	0.993	0.000
T49.7 Dental drugs, topically applied	0.007	0.993	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.007	0.993	0.000
T49.5 Ophthalmological drugs and preparations	0.007	0.993	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.007	0.993	0.000
T49.3 Emollients, demulcents and protectants	0.007	0.993	0.000
T49.2 Local astringents and local detergents	0.007	0.993	0.000
T49.1 Antipruritics	0.007	0.993	0.000
T47.0 Histamine H(2)-receptor antagonists	0.007	0.993	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.007	0.993	0.000
T45.8 Other primarily systemic and haematological agents	0.007	0.993	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.007	0.993	0.000
T45.6 Fibrinolysis-affecting drugs	0.007	0.993	0.000
T45.4 Iron and its compounds	0.007	0.993	0.000
T45.3 Enzymes, not elsewhere classified	0.007	0.993	0.000
T41.5 Therapeutic gases	0.007	0.993	0.000
T41.4 Anaesthetic, unspecified	0.007	0.993	0.000
T41.3 Local anaesthetics	0.007	0.993	0.000
T41.2 Other and unspecified general anaesthetics	0.007	0.993	0.000
T41.1 Intravenous anaesthetics	0.007	0.993	0.000
T41.0 Inhaled anaesthetics	0.007	0.993	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.007	0.993	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.007	0.993	0.000
T48.5 Anti-common-cold drugs	0.007	0.993	0.000
T48.4 Expectorants	0.007	0.993	0.000
T48.3 Antitussives	0.007	0.993	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.007	0.993	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.007	0.993	0.000
T48.0 Oxytocic drugs	0.007	0.993	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.007	0.993	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.007	0.993	0.000
T47.7 Emetics	0.007	0.993	0.000
T47.6 Antidiarrhoeal drugs	0.007	0.993	0.000
T47.5 Digestants	0.007	0.993	0.000
T47.4 Other laxatives	0.007	0.993	0.000
T47.3 Saline and osmotic laxatives	0.007	0.993	0.000
T47.2 Stimulant laxatives	0.007	0.993	0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.007	0.993	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.007	0.993	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.007	0.993	0.000
T39.1 4-Aminophenol derivatives	0.007	0.993	0.000
T45.2 Vitamins, not elsewhere classified	0.007	0.993	0.000
T50.4 Drugs affecting uric acid metabolism	0.007	0.993	0.000
L85.9 Epidermal thickening, unspecified	0.007	0.993	0.000
T50.8 Diagnostic agents	0.007	0.993	0.000
T50.7 Analeptics and opioid receptor antagonists	0.007	0.993	0.000
T50.5 Appetite depressants	0.007	0.993	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.007	0.993	0.000
T50.1 Loop [high-ceiling] diuretics	0.007	0.993	0.000
T50.0 Mineralocorticoids and their antagonists	0.007	0.993	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.006	0.993	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.006	0.993	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.006	0.993	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.006	0.993	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.006	0.994	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.006	0.994	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.006	0.994	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.006	0.994	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.006	0.994	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.006	0.994	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.006	0.994	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.006	0.994	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.006	0.994	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.006	0.994	0.000
T44.0 Anticholinesterase agents	0.006	0.994	0.000
T39.4 Antirheumatics, not elsewhere classified	0.006	0.994	0.000
T39.2 Pyrazolone derivatives	0.006	0.994	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.006	0.994	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.006	0.994	0.000
T93.2 Sequelae of other fractures of lower limb	0.006	0.994	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.006	0.994	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.006	0.994	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.000	0.994	0.006
E10-E14 Diabetes mellitus	0.006	0.994	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.006	0.994	0.000
T45.5 Anticoagulants	0.005	0.994	0.000
S20 Superficial injury of thorax	0.005	0.995	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.005	0.995	0.000
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters	0.005	0.995	0.000
S20.1 Other and unspecified superficial injuries of breast	0.005	0.995	0.000
S82.30 Fracture of lower end of tibia (closed)	0.005	0.995	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.005	0.995	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.000	0.995	0.005
E87.0 Hyperosmolality and hypernatraemia	0.005	0.995	0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.005	0.995	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.005	0.995	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.005	0.995	0.000
T43.9 Psychotropic drug, unspecified	0.005	0.995	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
E14 Unspecified diabetes mellitus	0.005	0.995	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.005	0.995	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.000	0.995	0.005
T42.4 Benzodiazepines	0.005	0.995	0.000
X62.9 Unspecified place	0.005	0.995	0.000
T43.6 Psychostimulants with abuse potential	0.004	0.996	0.000
E14.2 Withrenal complications	0.004	0.996	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.996	0.004
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.000	0.996	0.004
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.000	0.996	0.004
E14.5 With peripheral circulatory complications	0.004	0.996	0.000
E12 Malnutrition-related diabetes mellitus	0.004	0.996	0.000
H46 Optic neuritis	0.000	0.996	0.004
E14.8 With unspecified complications	0.004	0.996	0.000
S20.0 Contusion of breast	0.004	0.996	0.000
S20.7 Multiple superficial injuries of thorax	0.004	0.996	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.004	0.996	0.000
T42.3 Barbiturates	0.004	0.996	0.000
T42.2 Succinimides and oxazolidinediones	0.004	0.996	0.000
S20.2 Contusion of thorax	0.004	0.996	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.000	0.996	0.004
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.004	0.996	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.004	0.996	0.000
S20.4 Other superficial injuries of back wall of thorax	0.004	0.996	0.000
T39.0 Salicylates	0.004	0.996	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.000	0.996	0.004
E14.6 With other specified complications	0.004	0.996	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.004	0.996	0.000
K09.2 Other cysts of jaw	0.000	0.996	0.004
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.000	0.996	0.004
X41.0 Home	0.004	0.996	0.000
X41.8 Other specified place	0.004	0.996	0.000
X41.7 Farm	0.004	0.996	0.000
X41.6 Industrial and construction area	0.004	0.996	0.000
X41.5 Trade and service area	0.004	0.996	0.000
X41.4 Street and highway	0.004	0.996	0.000
X41.3 Sports and athletics area	0.004	0.996	0.000
X41.2 School, other institution and public administrative area	0.004	0.996	0.000
X41.1 Residential institution	0.004	0.996	0.000
E13 Other specified diabetes mellitus	0.004	0.996	0.000
S20.3 Other superficial injuries of front wall of thorax	0.004	0.996	0.000
E14.7 With multiple complications	0.004	0.996	0.000
E14.0 With coma	0.004	0.996	0.000
T42.0 Hydantoin derivatives	0.003	0.996	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.004	0.996	0.000
E14.1 With ketoacidosis	0.003	0.996	0.000
E14.4 With neurological complications	0.003	0.997	0.000
E14.3 With ophthalmic complications	0.003	0.997	0.000
E12.9 Without complications	0.003	0.997	0.000
E12.8 With unspecified complications	0.003	0.997	0.000
E12.7 With multiple complications	0.003	0.997	0.000
E12.6 With other specified complications	0.003	0.997	0.000
E12.5 With peripheral circulatory complications	0.003	0.997	0.000
E12.4 With neurological complications	0.003	0.997	0.000
E12.3 With ophthalmic complications	0.003	0.997	0.000
E12.2 With renal complications	0.003	0.997	0.000
E12.1 With ketoacidosis	0.003	0.997	0.000
E12.0 With coma	0.003	0.997	0.000
M48.02 Spinal stenosis (Cervical region)	0.003	0.997	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.997	0.003
D23.6 Skin of upper limb, including shoulder	0.003	0.997	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.003	0.997	0.000
X41.08 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, antiparkinsonism and psychotropic drugs, not elsewhere classified , Home ,While engaged in other specified activities	0.003	0.997	0.000
E13.8 With unspecified complications	0.003	0.997	0.000
E13.7 With multiple complications	0.003	0.997	0.000
E13.6 With other specified complications	0.003	0.997	0.000
E13.5 With peripheral circulatory complications	0.003	0.997	0.000
E13.4 With neurological complications	0.003	0.997	0.000
E13.3 With ophthalmic complications	0.003	0.997	0.000
E13.2 With renal complications	0.003	0.997	0.000
E13.1 With ketoacidosis	0.003	0.997	0.000
E13.0 With coma	0.003	0.997	0.000
T42.1 Iminostilbenes	0.003	0.997	0.000
E11.3 With ophthalmic complications	0.003	0.997	0.000
N83.0 Follicular cyst of ovary	0.000	0.997	0.003
S82.60 Fracture of lateral malleolus (closed)	0.003	0.997	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.003	0.997	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.997	0.003
D59.1 Other autoimmune haemolytic anaemias	0.003	0.997	0.000
S82.3 Fracture of lower end of tibia	0.003	0.997	0.000
G31.8 Other specified degenerative diseases of nervous system	0.003	0.997	0.000
M67.47 Ganglion, ankle and foot	0.003	0.997	0.000
M19.98 Arthrosis, unspecified (Other)	0.003	0.997	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.003	0.997	0.000
G31.0 Circumscribed brain atrophy	0.002	0.997	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.003	0.997	0.000
M19.96 Arthrosis, unspecified-Lower leg	0.003	0.997	0.000
D37.5 Rectum	0.003	0.997	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.002	0.998	0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.002	0.998	0.001
C73 Malignant neoplasm of thyroid gland	0.000	0.998	0.002
X40-X49 Accidental poisoning by and exposure to noxious substances	0.002	0.998	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
E11 Non-insulin-dependent diabetes mellitus	0.002	0.998	0.000
E11.6 With other specified complications	0.002	0.998	0.000
E13.9 Without complications	0.002	0.998	0.000
M19.9 Arthrosis, unspecified	0.002	0.998	0.000
K76.9 Liver disease, unspecified	0.000	0.998	0.002
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.002	0.998	0.000
X42.2 School, other institution and public administrative area	0.002	0.998	0.000
S82.6 Fracture of lateral malleolus	0.002	0.998	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.002	0.998	0.000
Q61.0 Congenital single renal cyst	0.002	0.998	0.000
O34.1 Maternal care for tumour of corpus uteri	0.002	0.998	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.002	0.998	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.002	0.998	0.000
S01.8 Open wound of other parts of head	0.000	0.998	0.002
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.998	0.002
S82.61 Fracture of lateral malleolus (open)	0.002	0.998	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.998	0.002
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.002	0.998	0.000
G31.2 Degeneration of nervous system due to alcohol	0.002	0.998	0.000
S01.7 Multiple open wounds of head	0.000	0.998	0.002
Q61.2 Polycystic kidney, adult type	0.002	0.998	0.000
J95.0 Tracheostomy malfunction	0.002	0.998	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.002	0.998	0.000
X62.0 Home	0.002	0.998	0.000
X62.8 Other specified place	0.002	0.998	0.000
X62.7 Farm	0.002	0.998	0.000
X62.6 Industrial and construction area	0.002	0.998	0.000
X62.5 Trade and service area	0.002	0.998	0.000
X62.4 Street and highway	0.002	0.998	0.000
X62.3 Sports and athletics area	0.002	0.998	0.000
X62.2 School, other institution and public administrative area	0.002	0.998	0.000
X62.1 Residential institution	0.002	0.998	0.000
I69.3 Sequelae of cerebral infarction	0.002	0.998	0.000
K60.2 Anal fissure, unspecified	0.000	0.998	0.002
S01.3 Open wound of ear	0.000	0.998	0.002
D59 Acquired haemolytic anaemia	0.002	0.998	0.000
X45 Accidental poisoning by and exposure to alcohol	0.002	0.998	0.000
E11.7 With multiple complications	0.002	0.998	0.000
Y84.1 Kidney dialysis	0.002	0.998	0.000
X48 Accidental poisoning by and exposure to pesticides	0.002	0.998	0.000
X46 Accidental poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours	0.002	0.998	0.000
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system	0.002	0.998	0.000
X40 Accidental poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics	0.002	0.998	0.000
M67.43 Ganglion, wrist	0.002	0.998	0.000
O34.4 Maternal care for other abnormalities of cervix	0.002	0.998	0.000
E11.8 With unspecified complications	0.002	0.998	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.998	0.002
Q61 Cystic kidney disease	0.002	0.998	0.000
X44 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
K76.6 Portal hypertension	0.000	0.998	0.002
X47 Accidental poisoning by and exposure to other gases and vapours	0.002	0.998	0.000
E11.0 With coma	0.002	0.998	0.000
X42.9 Unspecified place	0.002	0.998	0.000
X42.0 Home	0.002	0.998	0.000
X42.8 Other specified place	0.002	0.998	0.000
X42.7 Farm	0.002	0.998	0.000
X42.6 Industrial and construction area	0.002	0.998	0.000
X42.5 Trade and service area	0.002	0.998	0.000
X42.4 Street and highway	0.002	0.998	0.000
X42.3 Sports and athletics area	0.002	0.998	0.000
X42.1 Residential institution	0.002	0.998	0.000
M15.1 Heberden's nodes (with arthropathy)	0.002	0.998	0.000
N18.8 Other chronic renal failure	0.002	0.998	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.002	0.998	0.000
M81.9 Osteoporosis, unspecified	0.002	0.998	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.002	0.998	0.000
M15.8 Other polyarthrosis	0.002	0.998	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.002	0.998	0.000
S01.4 Open wound of cheek and temporomandibular area	0.000	0.998	0.002
M15 Polyarthrosis	0.002	0.998	0.000
C45.9 Mesothelioma, unspecified	0.002	0.998	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.002	0.998	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.002	0.998	0.000
M67.4 Ganglion	0.002	0.998	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.002	0.998	0.000
I42.9 Cardiomyopathy, unspecified	0.002	0.998	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.002	0.998	0.000
S82.31 Fracture of lower end of tibia (open)	0.002	0.998	0.000
M15.4 Erosive (osteo)arthrosis	0.002	0.998	0.000
K62.7 Radiation proctitis	0.000	0.998	0.002
O34.0 Maternal care for congenital malformation of uterus	0.002	0.998	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.002	0.998	0.000
E11.1 With ketoacidosis	0.002	0.998	0.000
M15.9 Polyarthrosis, unspecified	0.002	0.998	0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.000	0.998	0.002
T93 Sequelae of injuries of lower limb	0.002	0.998	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.002	0.998	0.000
X62.09 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified: Home: During unspecified activity	0.001	0.998	0.000
Q61.4 Renal dysplasia	0.002	0.998	0.000
M15.99 Polyosteoarthritis, unspecified	0.002	0.998	0.000
C45.7 Mesothelioma of other sites	0.002	0.998	0.000
D59.8 Other acquired haemolytic anaemias	0.002	0.998	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.002	0.998	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.002	0.998	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.002	0.998	0.000
D59.3 Haemolytic-uraemic syndrome	0.002	0.998	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.002	0.998	0.000
O34.3 Maternal care for cervical incompetence	0.002	0.998	0.000
S01 Open wound of head	0.000	0.998	0.002
M81.91 Osteoporosis, unspecified (Shoulder region)	0.002	0.998	0.000
Q61.5 Medullary cystic kidney	0.002	0.998	0.000
X40.9 Unspecified place	0.001	0.998	0.000
X40.0 Home	0.001	0.998	0.000
X40.8 Other specified place	0.001	0.998	0.000
X40.7 Farm	0.001	0.998	0.000
X40.6 Industrial and construction area	0.001	0.998	0.000
X40.5 Trade and service area	0.001	0.998	0.000
X40.4 Street and highway	0.001	0.998	0.000
X40.3 Sports and athletics area	0.001	0.998	0.000
X40.2 School, other institution and public administrative area	0.001	0.998	0.000
X40.1 Residential institution	0.001	0.998	0.000
X43.9 Unspecified place	0.001	0.998	0.000
X43.8 Other specified place	0.001	0.998	0.000
X43.7 Farm	0.001	0.998	0.000
X43.6 Industrial and construction area	0.001	0.998	0.000
X43.5 Trade and service area	0.001	0.998	0.000
X43.4 Street and highway	0.001	0.998	0.000
X43.3 Sports and athletics area	0.001	0.998	0.000
X43.2 School, other institution and public administrative area	0.001	0.998	0.000
X43.1 Residential institution	0.001	0.998	0.000
X43.0 Home	0.001	0.998	0.000
X45.9 Unspecified place	0.001	0.998	0.000
X45.8 Other specified place	0.001	0.998	0.000
X45.7 Farm	0.001	0.998	0.000
X45.6 Industrial and construction area	0.001	0.998	0.000
X45.5 Trade and service area	0.001	0.998	0.000
X45.4 Street and highway	0.001	0.998	0.000
X45.3 Sports and athletics area	0.001	0.998	0.000
X45.2 School, other institution and public administrative area	0.001	0.998	0.000
X45.1 Residential institution	0.001	0.998	0.000
X46.6 Industrial and construction area	0.001	0.998	0.000
X46.9 Unspecified place	0.001	0.998	0.000
X46.8 Other specified place	0.001	0.998	0.000
X46.7 Farm	0.001	0.998	0.000
X46.5 Trade and service area	0.001	0.998	0.000
X46.4 Street and highway	0.001	0.998	0.000
X46.3 Sports and athletics area	0.001	0.998	0.000
X46.2 School, other institution and public administrative area	0.001	0.998	0.000
X46.1 Residential institution	0.001	0.998	0.000
X46.0 Home	0.001	0.998	0.000
X48.9 Unspecified place	0.001	0.998	0.000
X48.8 Other specified place	0.001	0.998	0.000
X48.7 Farm	0.001	0.998	0.000
X48.6 Industrial and construction area	0.001	0.998	0.000
X48.5 Trade and service area	0.001	0.998	0.000
X48.4 Street and highway	0.001	0.998	0.000
X48.3 Sports and athletics area	0.001	0.998	0.000
X48.2 School, other institution and public administrative area	0.001	0.998	0.000
X48.1 Residential institution	0.001	0.998	0.000
X48.0 Home	0.001	0.998	0.000
S42.10 Fracture of scapula (closed)	0.000	0.998	0.002
N18.5 Chronic kidney disease, stage 5	0.002	0.998	0.000
X45.0 Home	0.002	0.998	0.000
Z75.8 Other problems related to medical facilities and other health care	0.002	0.998	0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations