TreeWAS – Variant ID: rs3790645

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	0.000	0.771	0.229
R21 Rash and other nonspecific skin eruption	0.000	0.922	0.078
C67 Malignant neoplasm of bladder	0.057	0.943	0.000
C67.6 Ureteric orifice	0.055	0.945	0.000
C67.2 Lateral wall of bladder	0.055	0.945	0.000
C67.4 Posterior wall of bladder	0.052	0.948	0.000
C67.3 Anterior wall of bladder	0.048	0.952	0.000
C67.9 Bladder, unspecified	0.046	0.954	0.000
C67.0 Trigone of bladder	0.045	0.954	0.000
C67.5 Bladder neck	0.044	0.956	0.000
C67.1 Dome of bladder	0.042	0.958	0.000
C67.7 Urachus	0.041	0.959	0.000
K14.8 Other diseases of tongue	0.000	0.963	0.037
C67.8 Overlapping lesion of bladder	0.035	0.965	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.966	0.034
N47 Redundant prepuce, phimosis and paraphimosis	0.030	0.970	0.000
E78.1 Pure hyperglyceridaemia	0.000	0.971	0.029
C64-C68 Malignant neoplasms of urinary tract	0.026	0.974	0.000
E78.8 Other disorders of lipoprotein metabolism	0.000	0.977	0.023
C64 Malignant neoplasm of kidney, except renal pelvis	0.023	0.977	0.000
E78.2 Mixed hyperlipidaemia	0.000	0.977	0.023
K14 Diseases of tongue	0.000	0.978	0.022
E78.3 Hyperchylomicronaemia	0.000	0.978	0.022
E78.6 Lipoprotein deficiency	0.000	0.978	0.022
K14.9 Disease of tongue, unspecified	0.000	0.980	0.020
E78.4 Other hyperlipidaemia	0.000	0.980	0.019
C34.9 Bronchus or lung, unspecified	0.000	0.981	0.019
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.981	0.019
K14.6 Glossodynia	0.000	0.983	0.017
C68 Malignant neoplasm of other and unspecified urinary organs	0.017	0.983	0.000
C34 Malignant neoplasm of bronchus and lung	0.000	0.983	0.017
C34.0 Main bronchus	0.000	0.983	0.017
C65 Malignant neoplasm of renal pelvis	0.017	0.983	0.000
E78.5 Hyperlipidaemia, unspecified	0.000	0.983	0.017
C34.3 Lower lobe, bronchus or lung	0.000	0.984	0.016
K14.5 Plicated tongue	0.000	0.984	0.016
K14.4 Atrophy of tongue papillae	0.000	0.984	0.016
K14.2 Median rhomboid glossitis	0.000	0.984	0.016
K14.1 Geographic tongue	0.000	0.984	0.016
K14.0 Glossitis	0.000	0.985	0.015
C66 Malignant neoplasm of ureter	0.015	0.985	0.000
K14.3 Hypertrophy of tongue papillae	0.000	0.986	0.014
C68.9 Urinary organ, unspecified	0.013	0.987	0.000
C68.8 Overlapping lesion of urinary organs	0.012	0.987	0.000
C68.1 Paraurethral glands	0.012	0.987	0.000
Z35 Supervision of high-risk pregnancy	0.012	0.988	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.988	0.012
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.012	0.988	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.012	0.988	0.000
C34.8 Overlapping lesion of bronchus and lung	0.000	0.988	0.012
Z35.8 Supervision of other high-risk pregnancies	0.012	0.988	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.011	0.989	0.000
C68.0 Urethra	0.011	0.989	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.010	0.990	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.010	0.990	0.000
I25.1 Atherosclerotic heart disease	0.000	0.991	0.009
Z35.5 Supervision of elderly primigravida	0.009	0.991	0.000
C34.1 Upper lobe, bronchus or lung	0.000	0.991	0.009
Z35.7 Supervision of high-risk pregnancy due to social problems	0.009	0.991	0.000
Z35.6 Supervision of very young primigravida	0.009	0.991	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.009	0.991	0.000
I25.3 Aneurysm of heart	0.000	0.991	0.009
C34.2 Middle lobe, bronchus or lung	0.000	0.991	0.009
Y40.0 Penicillins	0.000	0.991	0.009
I25 Chronic ischaemic heart disease	0.000	0.991	0.009
I25.4 Coronary artery aneurysm	0.000	0.992	0.008
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.993	0.007
K75.0 Abscess of liver	0.006	0.994	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.006	0.994	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.000	0.994	0.006
C38 Malignant neoplasm of heart, mediastinum and pleura	0.000	0.994	0.006
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.994	0.006
I25.6 Silent myocardial ischaemia	0.000	0.994	0.005
H90.3 Sensorineural hearing loss, bilateral	0.005	0.994	0.000
T18.1 Foreign body in oesophagus	0.000	0.995	0.005
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.000	0.995	0.005
C31 Malignant neoplasm of accessory sinuses	0.000	0.995	0.005
C30.0 Nasal cavity	0.000	0.995	0.005
C38.4 Pleura	0.000	0.995	0.005
C33 Malignant neoplasm of trachea	0.000	0.995	0.005
C37 Malignant neoplasm of thymus	0.000	0.995	0.005
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.000	0.995	0.005
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.995	0.004
C30.1 Middle ear	0.000	0.996	0.004
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.000	0.996	0.004
C38.3 Mediastinum, part unspecified	0.000	0.996	0.004
C38.2 Posterior mediastinum	0.000	0.996	0.004
C38.1 Anterior mediastinum	0.000	0.996	0.004
C38.0 Heart	0.000	0.996	0.004
I25.5 Ischaemic cardiomyopathy	0.000	0.996	0.004
N60.3 Fibrosclerosis of breast	0.004	0.996	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.004	0.996	0.000
C32 Malignant neoplasm of larynx	0.000	0.996	0.004
C31.9 Accessory sinus, unspecified	0.000	0.996	0.004
C31.8 Overlapping lesion of accessory sinuses	0.000	0.996	0.004
C31.3 Sphenoidal sinus	0.000	0.996	0.004
C31.2 Frontal sinus	0.000	0.996	0.004
C31.1 Ethmoidal sinus	0.000	0.996	0.004
C31.0 Maxillary sinus	0.000	0.996	0.004
C39.9 Ill-defined sites within the respiratory system	0.000	0.996	0.004
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.000	0.996	0.004
C39.0 Upper respiratory tract, part unspecified	0.000	0.996	0.004
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.000	0.996	0.004
C32.1 Supraglottis	0.000	0.997	0.003
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
Y45.1 Salicylates	0.003	0.997	0.000
S60.8 Other superficial injuries of wrist and hand	0.000	0.997	0.003
C32.8 Overlapping lesion of larynx	0.000	0.997	0.003
C32.3 Laryngeal cartilage	0.000	0.997	0.003
C32.2 Subglottis	0.000	0.997	0.003
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.003	0.997	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.003	0.997	0.000
T50.8 Diagnostic agents	0.003	0.997	0.000
S91.3 Open wound of other parts of foot	0.000	0.997	0.003
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.003	0.997	0.000
M95.0 Acquired deformity of nose	0.003	0.997	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.000	0.997	0.003
T50.1 Loop [high-ceiling] diuretics	0.003	0.997	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.003	0.997	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.003	0.997	0.000
S91.1 Open wound of toe(s) without damage to nail	0.000	0.997	0.003
S91 Open wound of ankle and foot	0.000	0.997	0.003
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.003	0.997	0.000
C32.9 Larynx, unspecified	0.000	0.997	0.003
T50.7 Analeptics and opioid receptor antagonists	0.003	0.997	0.000
T50.5 Appetite depressants	0.003	0.997	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.003	0.997	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.003	0.997	0.000
T50.0 Mineralocorticoids and their antagonists	0.003	0.997	0.000
S91.0 Open wound of ankle	0.000	0.997	0.003
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
T50.4 Drugs affecting uric acid metabolism	0.002	0.997	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.002	0.997	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.002	0.997	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.002	0.997	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.002	0.997	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.002	0.997	0.000
C32.0 Glottis	0.000	0.997	0.002
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.002	0.998	0.000
M75.5 Bursitis of shoulder	0.000	0.998	0.002
R23 Other skin changes	0.000	0.998	0.002
D68.6 Other Thrombophilia	0.002	0.998	0.000
N60.8 Other benign mammary dysplasias	0.000	0.998	0.002
M79.0 Rheumatism, unspecified	0.002	0.998	0.000
R23.0 Cyanosis	0.000	0.998	0.002
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.000	0.998	0.002
T91.9 Sequelae of unspecified injury of neck and trunk	0.000	0.998	0.002
T93.0 Sequelae of open wound of lower limb	0.000	0.998	0.002
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
S91.7 Multiple open wounds of ankle and foot	0.000	0.998	0.002
S91.2 Open wound of toe(s) with damage to nail	0.000	0.998	0.002
Y45.5 4-Aminophenol derivatives	0.002	0.998	0.000
R41.3 Other amnesia	0.000	0.998	0.002
M79.08 Rheumatism, unspecified (Other)	0.002	0.998	0.000
H90 Conductive and sensorineural hearing loss	0.002	0.998	0.000
T91.1 Sequelae of fracture of spine	0.000	0.998	0.002
T91 Sequelae of injuries of neck and trunk	0.000	0.998	0.002
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.002	0.998	0.000
H90.2 Conductive hearing loss, unspecified	0.002	0.998	0.000
I95.1 Orthostatic hypotension	0.000	0.998	0.002
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.002	0.998	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
K07.3 Anomalies of tooth position	0.000	0.998	0.002
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Y40 Systemic antibiotics	0.000	0.998	0.002
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.000	0.998	0.002
N42.1 Congestion and haemorrhage of prostate	0.000	0.998	0.002
R23.1 Pallor	0.000	0.998	0.002
H52.2 Astigmatism	0.002	0.998	0.000
H52.0 Hypermetropia	0.002	0.998	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
I44.2 Atrioventricular block, complete	0.002	0.998	0.000
M79.07 Rheumatism, unspecified (Ankle and foot)	0.002	0.998	0.000
M79.06 Rheumatism, unspecified (Lower leg)	0.002	0.998	0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M79.04 Rheumatism, unspecified (Hand)	0.002	0.998	0.000
M79.03 Rheumatism, unspecified (Forearm)	0.002	0.998	0.000
M79.02 Rheumatism, unspecified (Upper arm)	0.002	0.998	0.000
M79.01 Rheumatism, unspecified (Shoulder region)	0.002	0.998	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
R23.4 Changes in skin texture	0.000	0.998	0.002
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
W25.9 Unspecified place	0.002	0.998	0.000
E83.5 Disorders of calcium metabolism	0.000	0.998	0.002
M31.6 Other giant cell arteritis	0.000	0.998	0.002
E21.0 Primary hyperparathyroidism	0.000	0.998	0.002
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.998	0.002
K42.0 Umbilical hernia with obstruction, without gangrene	0.002	0.998	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.002	0.998	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.000	0.998	0.002
T91.4 Sequelae of injury of intrathoracic organs	0.000	0.998	0.002
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.000	0.998	0.002
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.002	0.998	0.000
R23.3 Spontaneous ecchymoses	0.000	0.998	0.002
T93.8 Sequelae of other specified injuries of lower limb	0.000	0.998	0.002
J35.8 Other chronic diseases of tonsils and adenoids	0.002	0.998	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
R45.8 Other symptoms and signs involving emotional state	0.000	0.998	0.002
T93.1 Sequelae of fracture of femur	0.000	0.998	0.002
T93 Sequelae of injuries of lower limb	0.000	0.998	0.002
Y40.6 Rifamycins	0.000	0.998	0.002
Y40.5 Aminoglycosides	0.000	0.998	0.002
Y40.4 Tetracyclines	0.000	0.998	0.002
Y40.2 Chloramphenicol group	0.000	0.998	0.002
M54.56 Low back pain (Lumbar region)	0.000	0.998	0.002
H52.1 Myopia	0.002	0.998	0.000
H90.0 Conductive hearing loss, bilateral	0.002	0.998	0.000
Y40.7 Antifungal antibiotics, systemically used	0.000	0.998	0.002
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.002	0.998	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.002	0.998	0.000
N21.1 Calculus in urethra	0.002	0.998	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.000	0.998	0.002
Y40.8 Other systemic antibiotics	0.000	0.998	0.002
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.002	0.998	0.000
G40.8 Other epilepsy	0.002	0.998	0.000
O86.4 Pyrexia of unknown origin following delivery	0.000	0.998	0.002
Y45.8 Other analgesics and antipyretics	0.002	0.998	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.002	0.998	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.002	0.998	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
C09.9 Tonsil, unspecified	0.002	0.998	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.000	0.998	0.002
Y40.3 Macrolides	0.000	0.998	0.002
Z01.4 Gynaecological examination (general)(routine)	0.002	0.998	0.000
D66 Hereditary factor VIII deficiency	0.000	0.998	0.002
D36.7 Other specified sites	0.000	0.998	0.002
M90.7 Fracture of bone in neoplastic disease	0.000	0.998	0.002
T91.3 Sequelae of injury of spinal cord	0.000	0.998	0.002
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.000	0.998	0.001
T93.4 Sequelae of injury of nerve of lower limb	0.000	0.998	0.001
H52.4 Presbyopia	0.001	0.998	0.000
O61.0 Failed medical induction of labour	0.002	0.998	0.000
H52 Disorders of refraction and accommodation	0.002	0.998	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.000	0.998	0.001
G60.0 Hereditary motor and sensory neuropathy	0.002	0.998	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.000	0.998	0.001
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.000	0.998	0.001
Y45.4 Antirheumatics	0.001	0.998	0.000
D68.2 Hereditary deficiency of other clotting factors	0.002	0.998	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.002	0.998	0.000
M95.2 Other acquired deformity of head	0.001	0.998	0.000
S10.9 Superficial injury of neck, part unspecified	0.000	0.998	0.001
M90.78 Fracture of bone in neoplastic disease (Other)	0.000	0.998	0.001
K26.7 Chronic without haemorrhage or perforation	0.000	0.998	0.001
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.001	0.998	0.000
M95.8 Other specified acquired deformities of musculoskeletal system	0.001	0.998	0.000
M95.5 Acquired deformity of pelvis	0.001	0.998	0.000
M95.4 Acquired deformity of chest and rib	0.001	0.998	0.000
M95.1 Cauliflower ear	0.001	0.998	0.000
R23.8 Other and unspecified skin changes	0.000	0.998	0.001
K75 Other inflammatory liver diseases	0.001	0.998	0.000
D68.5 Primary Thrombophilia	0.001	0.999	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.000	0.999	0.001
M95.3 Acquired deformity of neck	0.001	0.999	0.000
N80.3 Endometriosis of pelvic peritoneum	0.000	0.999	0.001
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.000	0.999	0.001
D16.4 Bones of skull and face	0.000	0.999	0.001
O86.2 Urinary tract infection following delivery	0.000	0.999	0.001
Y40.1 Cefalosporins and other -lactam antibiotics	0.000	0.999	0.001
O86 Other puerperal infections	0.000	0.999	0.001
T18 Foreign body in alimentary tract	0.000	0.999	0.001
K76.7 Hepatorenal syndrome	0.001	0.999	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.000	0.999	0.001
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.000	0.999	0.001
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.000	0.999	0.001
M90.74 Fracture of bone in neoplastic disease (Hand)	0.000	0.999	0.001
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.000	0.999	0.001
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.000	0.999	0.001
S62.40 Multiple fractures of metacarpal bones (closed)	0.001	0.999	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.001	0.999	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.000	0.999	0.001
J18.0 Bronchopneumonia, unspecified	0.000	0.999	0.001
O47.0 False labour before 37 completed weeks of gestation	0.001	0.999	0.000
D13.2 Duodenum	0.000	0.999	0.001
H52.6 Other disorders of refraction	0.001	0.999	0.000
H52.5 Disorders of accommodation	0.001	0.999	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.999	0.001
O86.0 Infection of obstetric surgical wound	0.000	0.999	0.001
W49.0 Home	0.000	0.999	0.001
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.001	0.999	0.000
D68 Other coagulation defects	0.001	0.999	0.000
D16.3 Short bones of lower limb	0.000	0.999	0.001
M46 Other inflammatory spondylopathies	0.001	0.999	0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.000	0.999	0.001
M95.96 Acquired deformity of musculoskeletal system, unspecified	0.001	0.999	0.000
A41.1 Septicaemia due to other specified staphylococcus	0.000	0.999	0.001
N42.2 Atrophy of prostate	0.000	0.999	0.001
R23.2 Flushing	0.000	0.999	0.001
R82.8 Abnormal findings on cytological and histological examination of urine	0.001	0.999	0.000
H20.0 Acute and subacute iridocyclitis	0.001	0.999	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.001	0.999	0.000
K75.2 Nonspecific reactive hepatitis	0.001	0.999	0.000
K75.1 Phlebitis of portal vein	0.001	0.999	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.000	0.999	0.001
S90-S99 Injuries to the ankle and foot	0.000	0.999	0.001
K04.6 Periapical abscess with sinus	0.000	0.999	0.001
M71.2 Synovial cyst of popliteal space [Baker]	0.000	0.999	0.001
O86.8 Other specified puerperal infections	0.000	0.999	0.001
O86.3 Other genito-urinary tract infections following delivery	0.000	0.999	0.001
O86.1 Other infection of genital tract following delivery	0.000	0.999	0.001
T18.8 Foreign body in other and multiple parts of alimentary tract	0.000	0.999	0.001
T18.4 Foreign body in colon	0.000	0.999	0.001
T18.3 Foreign body in small intestine	0.000	0.999	0.001
D68.8 Other specified coagulation defects	0.001	0.999	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.999	0.001
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.999	0.001
D68.1 Hereditary factor XI deficiency	0.001	0.999	0.000
K52.1 Toxic gastro-enteritis and colitis	0.001	0.999	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.001	0.999	0.000
M46.0 Spinal enthesopathy	0.001	0.999	0.000
O69.8 Labour and delivery complicated by other cord complications	0.001	0.999	0.000
T18.5 Foreign body in anus and rectum	0.000	0.999	0.001
D68.4 Acquired coagulation factor deficiency	0.001	0.999	0.000
M46.8 Other specified inflammatory spondylopathies	0.001	0.999	0.000
M46.5 Other infective spondylopathies	0.001	0.999	0.000
S12.1 Fracture of second cervical vertebra	0.001	0.999	0.000
T93.2 Sequelae of other fractures of lower limb	0.000	0.999	0.001
Y40.9 Systemic antibiotic, unspecified	0.000	0.999	0.001
Y45.2 Propionic acid derivatives	0.001	0.999	0.000
Z36.8 Other antenatal screening	0.000	0.999	0.001
O90 Complications of the puerperium, not elsewhere classified	0.000	0.999	0.001
S99 Other and unspecified injuries of ankle and foot	0.000	0.999	0.001
I50.9 Heart failure, unspecified	0.000	0.999	0.001
J86.9 Pyothorax without fistula	0.001	0.999	0.000
N88.8 Other specified noninflammatory disorders of cervix uteri	0.001	0.999	0.000
O90.9 Complication of the puerperium, unspecified	0.000	0.999	0.001
S00.9 Superficial injury of head, part unspecified	0.000	0.999	0.001
M46.06 Spinal enthesopathy (Lumbar region)	0.001	0.999	0.000
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)	0.001	0.999	0.000
M71.29 Synovial cyst of popliteal space [Baker]-Site unspec	0.000	0.999	0.001
M71.28 Synovial cyst of popliteal space [Baker]-Other	0.000	0.999	0.001
M71.27 Synovial cyst of popliteal space [Baker]-Ankle/Foot	0.000	0.999	0.001
M71.25 Synovial cyst of popliteal space [Baker]-Pelvic/Thigh	0.000	0.999	0.001
M71.24 Synovial cyst of popliteal space [Baker]-Hand	0.000	0.999	0.001
M71.23 Synovial cyst of popliteal space [Baker]-Forearm	0.000	0.999	0.001
M71.22 Synovial cyst of popliteal space [Baker]-Upper arm	0.000	0.999	0.001
M71.21 Synovial cyst of popliteal space [Baker]-Shldr region	0.000	0.999	0.001
M71.20 Synovial cyst of popliteal space [Baker]-Mult sites	0.000	0.999	0.001
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.999	0.001
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.000	0.999	0.001
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.001	0.999	0.000
K75.8 Other specified inflammatory liver diseases	0.001	0.999	0.000
M46.2 Osteomyelitis of vertebra	0.001	0.999	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.001	0.999	0.000
M88.9 Paget's disease of bone, unspecified	0.000	0.999	0.001
S90.3 Contusion of other and unspecified parts of foot	0.000	0.999	0.001
S99.9 Unspecified injury of ankle and foot	0.000	0.999	0.001
S98 Traumatic amputation of ankle and foot	0.000	0.999	0.001
S97 Crushing injury of ankle and foot	0.000	0.999	0.001
S95 Injury of blood vessels at ankle and foot level	0.000	0.999	0.001
S94 Injury of nerves at ankle and foot level	0.000	0.999	0.001
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.000	0.999	0.001
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.999	0.001
M15.2 Bouchard's nodes (with arthropathy)	0.000	0.999	0.001
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.001	0.999	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.000	0.999	0.001
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.000	0.999	0.001
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.000	0.999	0.001
T18.2 Foreign body in stomach	0.000	0.999	0.001
T18.0 Foreign body in mouth	0.000	0.999	0.001
Z64.0 Problems related to unwanted pregnancy	0.001	0.999	0.000
M13.98 Arthritis, unspecified (Other)	0.001	0.999	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.001	0.999	0.000
M46.09 Spinal enthesopathy (Site unspecified)	0.001	0.999	0.000
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M46.07 Spinal enthesopathy (Lumbosacral region)	0.001	0.999	0.000
M46.05 Spinal enthesopathy (Thoracolumbar region)	0.001	0.999	0.000
M46.04 Spinal enthesopathy (Thoracic region)	0.001	0.999	0.000
M46.03 Spinal enthesopathy (Cervicothoracic region)	0.001	0.999	0.000
M46.02 Spinal enthesopathy (Cervical region)	0.001	0.999	0.000
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)	0.001	0.999	0.000
M46.00 Spinal enthesopathy (Multiple sites in spine)	0.001	0.999	0.000
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)	0.001	0.999	0.000
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)	0.001	0.999	0.000
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)	0.001	0.999	0.000
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)	0.001	0.999	0.000
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)	0.001	0.999	0.000
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)	0.001	0.999	0.000
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)	0.001	0.999	0.000
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)	0.001	0.999	0.000
M71.16 Other infective bursitis (Lower leg)	0.001	0.999	0.000
S62.60 Fracture of other finger (closed)	0.000	0.999	0.001
S90 Superficial injury of ankle and foot	0.000	0.999	0.001
S12.11 Fracture of second cervical vertebra (open)	0.001	0.999	0.000
H65.3 Chronic mucoid otitis media	0.001	0.999	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.999	0.001
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.999	0.001
N88.1 Old laceration of cervix uteri	0.001	0.999	0.000
O90.5 Postpartum thyroiditis	0.000	0.999	0.001
O90.4 Postpartum acute renal failure	0.000	0.999	0.001
O90.3 Cardiomyopathy in the puerperium	0.000	0.999	0.001
O90.0 Disruption of Caesarean section wound	0.000	0.999	0.001
S99.7 Multiple injuries of ankle and foot	0.000	0.999	0.001
M46.59 Other infective spondylopathies (Site unspecified)	0.001	0.999	0.000
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M46.57 Other infective spondylopathies (Lumbosacral region)	0.001	0.999	0.000
M46.56 Other infective spondylopathies (Lumbar region)	0.001	0.999	0.000
M46.55 Other infective spondylopathies (Thoracolumbar region)	0.001	0.999	0.000
M46.54 Other infective spondylopathies (Thoracic region)	0.001	0.999	0.000
M46.53 Other infective spondylopathies (Cervicothoracic region)	0.001	0.999	0.000
M46.52 Other infective spondylopathies (Cervical region)	0.001	0.999	0.000
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)	0.001	0.999	0.000
M46.50 Other infective spondylopathies (Multiple sites in spine)	0.001	0.999	0.000
M46.89 Other specified inflammatory spondylopathies (Site unspecified)	0.001	0.999	0.000
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)	0.001	0.999	0.000
M46.86 Other specified inflammatory spondylopathies (Lumbar region)	0.001	0.999	0.000
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)	0.001	0.999	0.000
M46.84 Other specified inflammatory spondylopathies (Thoracic region)	0.001	0.999	0.000
M46.83 Other specified inflammatory spondylopathies (Cervicothoracic region)	0.001	0.999	0.000
M46.82 Other specified inflammatory spondylopathies (Cervical region)	0.001	0.999	0.000
M46.81 Other specified inflammatory spondylopathies (Occipito-atlanto-axial region)	0.001	0.999	0.000
M46.80 Other specified inflammatory spondylopathies (Multiple sites in spine)	0.001	0.999	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.999	0.001
S94.9 Injury of unspecified nerve at ankle and foot level	0.000	0.999	0.001
S94.8 Injury of other nerves at ankle and foot level	0.000	0.999	0.001
S94.7 Injury of multiple nerves at ankle and foot level	0.000	0.999	0.001
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.000	0.999	0.001
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.000	0.999	0.001
S94.1 Injury of medial plantar nerve	0.000	0.999	0.001
S94.0 Injury of lateral plantar nerve	0.000	0.999	0.001
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.000	0.999	0.001
S95.8 Injury of other blood vessels at ankle and foot level	0.000	0.999	0.001
S95.7 Injury of multiple blood vessels at ankle and foot level	0.000	0.999	0.001
S95.2 Injury of dorsal vein of foot	0.000	0.999	0.001
S95.1 Injury of plantar artery of foot	0.000	0.999	0.001
S95.0 Injury of dorsal artery of foot	0.000	0.999	0.001
S97.8 Crushing injury of other parts of ankle and foot	0.000	0.999	0.001
S97.1 Crushing injury of toe(s)	0.000	0.999	0.001
S97.0 Crushing injury of ankle	0.000	0.999	0.001
S98.4 Traumatic amputation of foot, level unspecified	0.000	0.999	0.001
S98.3 Traumatic amputation of other parts of foot	0.000	0.999	0.001
S98.2 Traumatic amputation of two or more toes	0.000	0.999	0.001
S98.1 Traumatic amputation of one toe	0.000	0.999	0.001
S98.0 Traumatic amputation of foot at ankle level	0.000	0.999	0.001
M46.19 Sacroiliitis, not elsewhere classified-Site unspe	0.001	0.999	0.000
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral	0.001	0.999	0.000
M46.16 Sacroiliitis, not elsewhere classified-Lumbar	0.001	0.999	0.000
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar	0.001	0.999	0.000
M46.14 Sacroiliitis, not elsewhere classified-Thoracic	0.001	0.999	0.000
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic	0.001	0.999	0.000
M46.12 Sacroiliitis, not elsewhere classified-Cervical	0.001	0.999	0.000
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl	0.001	0.999	0.000
M46.10 Sacroiliitis, not elsewhere classified-Mult site	0.001	0.999	0.000
M46.29 Osteomyelitis of vertebra (Site unspecified)	0.001	0.999	0.000
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M46.27 Osteomyelitis of vertebra (Lumbosacral region)	0.001	0.999	0.000
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)	0.001	0.999	0.000
M46.24 Osteomyelitis of vertebra (Thoracic region)	0.001	0.999	0.000
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)	0.001	0.999	0.000
M46.22 Osteomyelitis of vertebra (Cervical region)	0.001	0.999	0.000
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)	0.001	0.999	0.000
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)	0.001	0.999	0.000
M88.98 Paget's disease of bone, unspecified (Other)	0.000	0.999	0.001
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.000	0.999	0.001
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.000	0.999	0.001
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
M88.94 Paget's disease of bone, unspecified (Hand)	0.000	0.999	0.001
M88.93 Paget's disease of bone, unspecified (Forearm)	0.000	0.999	0.001
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.000	0.999	0.001
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.000	0.999	0.001
S92.70 Multiple fractures of foot (closed)	0.000	0.999	0.001
A08.1 Acute gastro-enteropathy due to Norwalk agent	0.000	0.999	0.001
E21.3 Hyperparathyroidism, unspecified	0.000	0.999	0.001
M22.4 Chondromalacia patellae	0.001	0.999	0.000
S89.9 Unspecified injury of lower leg	0.001	0.999	0.000
S93.0 Dislocation of ankle joint	0.000	0.999	0.001
D16.1 Short bones of upper limb	0.000	0.999	0.001
D68.9 Coagulation defect, unspecified	0.001	0.999	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.000	0.999	0.001
H02.1 Ectropion of eyelid	0.000	0.999	0.001
K05.3 Chronic periodontitis	0.001	0.999	0.000
K50.9 Crohn's disease, unspecified	0.000	0.999	0.001
O90.1 Disruption of perineal obstetric wound	0.000	0.999	0.001
S90.7 Multiple superficial injuries of ankle and foot	0.000	0.999	0.001
S90.2 Contusion of toe(s) with damage to nail	0.000	0.999	0.001
S90.1 Contusion of toe(s) without damage to nail	0.000	0.999	0.001
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.000	0.999	0.001
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.001	0.999	0.000
M46.26 Osteomyelitis of vertebra (Lumbar region)	0.001	0.999	0.000
M71.97 Bursopathy, unspecified (Ankle and foot)	0.001	0.999	0.000
D69.9 Haemorrhagic condition, unspecified	0.000	0.999	0.001
H52.7 Disorder of refraction, unspecified	0.001	0.999	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.001	0.999	0.000
M46.4 Discitis, unspecified	0.001	0.999	0.000
R82.1 Myoglobinuria	0.001	0.999	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.000	0.999	0.001
S99.8 Other specified injuries of ankle and foot	0.000	0.999	0.001
T18.9 Foreign body in alimentary tract, part unspecified	0.000	0.999	0.001
S72.30 Fracture of shaft of femur (closed)	0.001	0.999	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.999	0.001
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.999	0.001
O69.0 Labour and delivery complicated by prolapse of cord	0.001	0.999	0.000
O90.2 Haematoma of obstetric wound	0.000	0.999	0.001
S92.7 Multiple fractures of foot	0.000	0.999	0.001
X41.9 Unspecified place	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations