TreeWAS – Variant ID: rs3802842

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D12.5 Sigmoid colon	1.000	0.000	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	1.000	0.000	0.000
D12.8 Rectum	1.000	0.000	0.000
D12.2 Ascending colon	1.000	0.000	0.000
D12.3 Transverse colon	1.000	0.000	0.000
D12.4 Descending colon	0.999	0.001	0.000
C15-C26 Malignant neoplasms of digestive organs	0.998	0.002	0.000
C18 Malignant neoplasm of colon	0.998	0.002	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.997	0.003	0.000
C20 Malignant neoplasm of rectum	0.996	0.004	0.000
C18.7 Sigmoid colon	0.994	0.006	0.000
D12.6 Colon, unspecified	0.993	0.007	0.000
K62.1 Rectal polyp	0.983	0.017	0.000
C18.3 Hepatic flexure	0.950	0.050	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.948	0.052	0.000
C18.6 Descending colon	0.927	0.073	0.000
C26.0 Intestinal tract, part unspecified	0.918	0.082	0.000
C23 Malignant neoplasm of gallbladder	0.903	0.097	0.000
C18.9 Colon, unspecified	0.896	0.104	0.000
C18.4 Transverse colon	0.840	0.160	0.000
D12.7 Rectosigmoid junction	0.797	0.203	0.000
C18.8 Overlapping lesion of colon	0.794	0.206	0.000
D12.0 Caecum	0.774	0.226	0.000
D12.1 Appendix	0.727	0.273	0.000
C26.8 Overlapping lesion of digestive system	0.679	0.320	0.000
C26.1 Spleen	0.679	0.320	0.000
D12.9 Anus and anal canal	0.662	0.338	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.661	0.339	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.639	0.361	0.000
C26.9 Ill-defined sites within the digestive system	0.622	0.378	0.000
K63.5 Polyp of colon	0.606	0.394	0.000
C18.5 Splenic flexure	0.586	0.414	0.000
C22.9 Liver, unspecified	0.543	0.457	0.000
C24.9 Biliary tract, unspecified	0.510	0.490	0.000
C22.7 Other specified carcinomas of liver	0.474	0.526	0.000
C22.4 Other sarcomas of liver	0.474	0.526	0.000
C22.3 Angiosarcoma of liver	0.474	0.526	0.000
C22.2 Hepatoblastoma	0.474	0.526	0.000
C24.8 Overlapping lesion of biliary tract	0.458	0.541	0.000
C18.0 Caecum	0.446	0.554	0.000
C17 Malignant neoplasm of small intestine	0.441	0.558	0.001
C18.1 Appendix	0.427	0.573	0.001
C24.0 Extrahepatic bile duct	0.418	0.582	0.000
C25 Malignant neoplasm of pancreas	0.414	0.586	0.000
C22.0 Liver cell carcinoma	0.411	0.589	0.000
C22.1 Intrahepatic bile duct carcinoma	0.374	0.626	0.000
C16 Malignant neoplasm of stomach	0.365	0.635	0.000
C17.9 Small intestine, unspecified	0.357	0.643	0.000
C24.1 Ampulla of Vater	0.344	0.656	0.000
C25.1 Body of pancreas	0.324	0.676	0.000
C18.2 Ascending colon	0.322	0.678	0.000
C17.8 Overlapping lesion of small intestine	0.317	0.683	0.001
C17.3 Meckel's diverticulum	0.317	0.683	0.001
C21 Malignant neoplasm of anus and anal canal	0.308	0.691	0.002
C17.1 Jejunum	0.297	0.702	0.001
C25.8 Overlapping lesion of pancreas	0.297	0.703	0.000
C25.4 Endocrine pancreas	0.297	0.703	0.000
C25.3 Pancreatic duct	0.294	0.706	0.000
C25.7 Other parts of pancreas	0.291	0.708	0.000
C16.5 Lesser curvature of stomach, unspecified	0.290	0.710	0.000
C25.2 Tail of pancreas	0.275	0.725	0.000
C16.6 Greater curvature of stomach, unspecified	0.268	0.732	0.000
C16.8 Overlapping lesion of stomach	0.262	0.738	0.000
C16.4 Pylorus	0.262	0.738	0.000
C16.3 Pyloric antrum	0.250	0.750	0.000
C16.0 Cardia	0.247	0.753	0.000
C16.1 Fundus of stomach	0.229	0.771	0.000
C21.2 Cloacogenic zone	0.221	0.778	0.001
C25.0 Head of pancreas	0.222	0.778	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.214	0.785	0.001
C17.2 Ileum	0.211	0.788	0.001
C15 Malignant neoplasm of oesophagus	0.180	0.819	0.000
C17.0 Duodenum	0.166	0.833	0.001
C16.2 Body of stomach	0.166	0.833	0.001
K62 Other diseases of anus and rectum	0.165	0.835	0.000
K62.0 Anal polyp	0.161	0.839	0.000
C16.9 Stomach, unspecified	0.157	0.843	0.000
C25.9 Pancreas, unspecified	0.154	0.846	0.000
C15.3 Upper third of oesophagus	0.134	0.865	0.000
K62.2 Anal prolapse	0.133	0.867	0.000
C15.1 Thoracic part of oesophagus	0.130	0.869	0.000
C15.8 Overlapping lesion of oesophagus	0.130	0.870	0.000
C15.2 Abdominal part of oesophagus	0.130	0.870	0.000
C21.0 Anus, unspecified	0.124	0.875	0.002
C15.0 Cervical part of oesophagus	0.122	0.877	0.000
K62.9 Disease of anus and rectum, unspecified	0.121	0.879	0.000
K62.6 Ulcer of anus and rectum	0.116	0.884	0.000
K62.4 Stenosis of anus and rectum	0.112	0.888	0.000
C15.4 Middle third of oesophagus	0.102	0.898	0.000
C21.1 Anal canal	0.090	0.907	0.002
K62.7 Radiation proctitis	0.073	0.926	0.000
K63 Other diseases of intestine	0.064	0.936	0.000
K63.9 Disease of intestine, unspecified	0.063	0.937	0.000
C15.9 Oesophagus, unspecified	0.059	0.941	0.000
K62.3 Rectal prolapse	0.047	0.953	0.000
K63.1 Perforation of intestine (nontraumatic)	0.037	0.963	0.000
K55-K64 Other diseases of intestines	0.033	0.967	0.000
T39.0 Salicylates	0.000	0.968	0.032
K63.0 Abscess of intestine	0.032	0.968	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.968	0.032
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.969	0.031
K63.4 Enteroptosis	0.029	0.970	0.000
K62.5 Haemorrhage of anus and rectum	0.029	0.971	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.972	0.028
K64 Haemorrhoids and perianal venous thrombosis	0.024	0.976	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.976	0.024
T39.4 Antirheumatics, not elsewhere classified	0.000	0.977	0.022
T39.2 Pyrazolone derivatives	0.000	0.977	0.022
C15.5 Lower third of oesophagus	0.021	0.978	0.001
K63.2 Fistula of intestine	0.020	0.980	0.000
T39.1 4-Aminophenol derivatives	0.000	0.980	0.020
K63.3 Ulcer of intestine	0.019	0.981	0.000
K59 Other functional intestinal disorders	0.018	0.982	0.000
K64.9 Haemorrhoids, unspecified	0.017	0.982	0.000
K64.8 Other specified haemorrhoids	0.017	0.982	0.000
K64.5 Perianal venous thrombosis	0.017	0.982	0.000
K64.4 Residual haemorrhoidal skin tags	0.017	0.982	0.000
K64.3 Fourth degree haemorrhoids	0.017	0.982	0.000
K64.2 Third degree haemorrhoids	0.017	0.982	0.000
K64.1 Second degree haemorrhoids	0.017	0.982	0.000
K64.0 First degree haemorrhoids	0.017	0.982	0.000
K59.8 Other specified functional intestinal disorders	0.016	0.984	0.000
K56 Paralytic ileus and intestinal obstruction without hernia	0.016	0.984	0.000
K56.2 Volvulus	0.016	0.984	0.000
D37.4 Colon	0.015	0.985	0.000
K59.3 Megacolon, not elsewhere classified	0.014	0.986	0.000
K56.1 Intussusception	0.014	0.986	0.000
K59.4 Anal spasm	0.013	0.986	0.000
K59.2 Neurogenic bowel, not elsewhere classified	0.013	0.987	0.000
K58 Irritable bowel syndrome	0.013	0.987	0.000
K56.5 Intestinal adhesions [bands] with obstruction	0.013	0.987	0.000
K56.3 Gallstone ileus	0.012	0.987	0.000
K61 Abscess of anal and rectal regions	0.012	0.988	0.000
K59.1 Functional diarrhoea	0.011	0.989	0.000
S42.20 Fracture of upper end of humerus (closed)	0.010	0.990	0.000
K61.2 Anorectal abscess	0.009	0.991	0.000
K55 Vascular disorders of intestine	0.009	0.991	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.991	0.009
K58.0 Irritable bowel syndrome with diarrhoea	0.009	0.991	0.000
K61.4 Intrasphincteric abscess	0.008	0.991	0.000
K56.0 Paralytic ileus	0.008	0.992	0.000
K61.1 Rectal abscess	0.008	0.992	0.000
K59.9 Functional intestinal disorder, unspecified	0.008	0.992	0.000
K55.0 Acute vascular disorders of intestine	0.008	0.992	0.000
K61.3 Ischiorectal abscess	0.008	0.992	0.000
Z98.0 Intestinal bypass and anastomosis status	0.007	0.993	0.000
D86.1 Sarcoidosis of lymph nodes	0.006	0.994	0.000
K55.1 Chronic vascular disorders of intestine	0.006	0.994	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.006	0.994	0.000
W44.0 Home	0.000	0.994	0.006
S42.2 Fracture of upper end of humerus	0.006	0.994	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.006	0.994	0.000
D86 Sarcoidosis	0.006	0.994	0.000
K56.7 Ileus, unspecified	0.005	0.995	0.000
Z98.8 Other specified postsurgical states	0.005	0.995	0.000
S00.9 Superficial injury of head, part unspecified	0.000	0.995	0.005
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.005	0.995	0.000
M70.22 Olecranon bursitis-Upper arm	0.000	0.995	0.005
D80-D89 Certain disorders involving the immune mechanism	0.005	0.995	0.000
K62.8 Other specified diseases of anus and rectum	0.005	0.995	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.005	0.995	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.005	0.995	0.000
J06.9 Acute upper respiratory infection, unspecified	0.005	0.995	0.000
Z98 Other postsurgical states	0.005	0.995	0.000
D86.9 Sarcoidosis, unspecified	0.005	0.995	0.000
K55.9 Vascular disorder of intestine, unspecified	0.005	0.995	0.000
S79.9 Unspecified injury of hip and thigh	0.005	0.995	0.000
S42.21 Fracture of upper end of humerus (open)	0.004	0.995	0.000
E34.9 Endocrine disorder, unspecified	0.005	0.995	0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.004	0.995	0.000
J81 Pulmonary oedema	0.000	0.995	0.005
D84 Other immunodeficiencies	0.004	0.996	0.000
K56.4 Other impaction of intestine	0.004	0.996	0.000
D37.5 Rectum	0.004	0.996	0.000
D86.3 Sarcoidosis of skin	0.004	0.996	0.000
D86.0 Sarcoidosis of lung	0.004	0.996	0.000
D80 Immunodeficiency with predominantly antibody defects	0.004	0.996	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.004	0.996	0.000
K55.8 Other vascular disorders of intestine	0.004	0.996	0.001
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.004	0.996	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.004	0.996	0.000
D82 Immunodeficiency associated with other major defects	0.004	0.996	0.000
D84.8 Other specified immunodeficiencies	0.004	0.996	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.996	0.004
I85.9 Oesophageal varices without bleeding	0.004	0.996	0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.004	0.996	0.000
E24.9 Cushing's syndrome, unspecified	0.004	0.996	0.000
D83 Common variable immunodeficiency	0.004	0.996	0.000
D81 Combined immunodeficiencies	0.004	0.996	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.004	0.996	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.004	0.996	0.000
D86.8 Sarcoidosis of other and combined sites	0.004	0.996	0.000
D89.3 Immune reconstitution syndrome	0.004	0.996	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.004	0.996	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.004	0.996	0.000
J80 Adult respiratory distress syndrome	0.000	0.996	0.004
S91 Open wound of ankle and foot	0.000	0.996	0.004
I72.4 Aneurysm of artery of lower extremity	0.004	0.996	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.000	0.996	0.004
K12.3 Oral mucositis (ulcerative)	0.000	0.996	0.004
G61.9 Inflammatory polyneuropathy, unspecified	0.004	0.996	0.000
D89.1 Cryoglobulinaemia	0.003	0.996	0.000
I72.0 Aneurysm of carotid artery	0.004	0.996	0.000
S91.1 Open wound of toe(s) without damage to nail	0.000	0.996	0.003
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.996	0.004
E34 Other endocrine disorders	0.003	0.996	0.000
D82.1 Di George's syndrome	0.003	0.997	0.000
D84.1 Defects in the complement system	0.003	0.997	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.003	0.997	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.003	0.997	0.000
Z98.1 Arthrodesis status	0.003	0.997	0.000
Z81.8 Family history of other mental and behavioural disorders	0.000	0.997	0.003
Z83.7 Family history of diseases of the digestive system	0.003	0.997	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.997	0.003
D80.8 Other immunodeficiencies with predominantly antibody defects	0.003	0.997	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.003	0.997	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.003	0.997	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.003	0.997	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.003	0.997	0.000
G62.8 Other specified polyneuropathies	0.003	0.997	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.997	0.003
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.003	0.997	0.000
D84.9 Immunodeficiency, unspecified	0.003	0.997	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.003	0.997	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.000	0.997	0.003
E24 Cushing's syndrome	0.003	0.997	0.000
S90-S99 Injuries to the ankle and foot	0.000	0.997	0.003
D82.9 Immunodeficiency associated with major defect, unspecified	0.003	0.997	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.003	0.997	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.003	0.997	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.003	0.997	0.000
D82.2 Immunodeficiency with short-limbed stature	0.003	0.997	0.000
D82.0 Wiskott-Aldrich syndrome	0.003	0.997	0.000
I72 Other aneurysm	0.003	0.997	0.000
J84.8 Other specified interstitial pulmonary diseases	0.000	0.997	0.003
S91.3 Open wound of other parts of foot	0.000	0.997	0.003
J82 Pulmonary eosinophilia, not elsewhere classified	0.000	0.997	0.003
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.003	0.997	0.000
G62.0 Drug-induced polyneuropathy	0.003	0.997	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.003	0.997	0.000
S99 Other and unspecified injuries of ankle and foot	0.000	0.997	0.003
D37.6 Liver, gallbladder and bile ducts	0.003	0.997	0.000
I72.9 Aneurysm of unspecified site	0.003	0.997	0.000
D81.9 Combined immunodeficiency, unspecified	0.003	0.997	0.000
D81.8 Other combined immunodeficiencies	0.003	0.997	0.000
D81.7 Major histocompatibility complex class II deficiency	0.003	0.997	0.000
D81.6 Major histocompatibility complex class I deficiency	0.003	0.997	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.003	0.997	0.000
D81.4 Nezelof's syndrome	0.003	0.997	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.003	0.997	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.003	0.997	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.003	0.997	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.003	0.997	0.000
D83.9 Common variable immunodeficiency, unspecified	0.003	0.997	0.000
D83.8 Other common variable immunodeficiencies	0.003	0.997	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.003	0.997	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.003	0.997	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.003	0.997	0.000
E26 Hyperaldosteronism	0.003	0.997	0.000
E26.0 Primary hyperaldosteronism	0.003	0.997	0.000
G61 Inflammatory polyneuropathy	0.003	0.997	0.000
S91.2 Open wound of toe(s) with damage to nail	0.000	0.997	0.003
S91.0 Open wound of ankle	0.000	0.997	0.003
S42 Fracture of shoulder and upper arm	0.003	0.997	0.000
G61.8 Other inflammatory polyneuropathies	0.003	0.997	0.000
S90 Superficial injury of ankle and foot	0.000	0.997	0.003
S42.10 Fracture of scapula (closed)	0.003	0.997	0.000
G30.9 Alzheimer's disease, unspecified	0.003	0.997	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.000	0.997	0.003
J84 Other interstitial pulmonary diseases	0.000	0.997	0.003
S42.1 Fracture of scapula	0.003	0.997	0.000
S99.8 Other specified injuries of ankle and foot	0.000	0.997	0.003
G62 Other polyneuropathies	0.003	0.997	0.000
H21.8 Other specified disorders of iris and ciliary body	0.000	0.997	0.003
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.997	0.003
E20-E35 Disorders of other endocrine glands	0.003	0.997	0.000
S93.1 Dislocation of toe(s)	0.000	0.997	0.003
T43.2 Other and unspecified antidepressants	0.000	0.997	0.003
E34.3 Short stature, not elsewhere classified	0.003	0.997	0.000
S91.7 Multiple open wounds of ankle and foot	0.000	0.997	0.003
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.000	0.997	0.003
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.997	0.003
S90.0 Contusion of ankle	0.000	0.997	0.003
D37.3 Appendix	0.003	0.997	0.000
E34.8 Other specified endocrine disorders	0.003	0.997	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.997	0.003
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.997	0.003
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.997	0.003
E26.9 Hyperaldosteronism, unspecified	0.003	0.997	0.000
E34.5 Androgen resistance syndrome	0.003	0.997	0.000
E34.4 Constitutional tall stature	0.003	0.997	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.003	0.997	0.000
E34.1 Other hypersecretion of intestinal hormones	0.003	0.997	0.000
E24.0 Pituitary-dependent Cushing's disease	0.003	0.997	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.000	0.997	0.003
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.997	0.003
K63.8 Other specified diseases of intestine	0.003	0.997	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.003	0.997	0.000
W44 Foreign body entering into or through eye or natural orifice	0.000	0.997	0.003
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.003	0.997	0.000
D37.2 Small intestine	0.003	0.997	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.000	0.997	0.003
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.000	0.997	0.003
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.000	0.997	0.003
S99.9 Unspecified injury of ankle and foot	0.000	0.997	0.003
I49.9 Cardiac arrhythmia, unspecified	0.003	0.997	0.000
Z98.2 Presence of cerebrospinal fluid drainage device	0.003	0.997	0.000
I72.3 Aneurysm of iliac artery	0.003	0.997	0.000
T43.9 Psychotropic drug, unspecified	0.000	0.997	0.003
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.997	0.003
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.997	0.003
E24.8 Other Cushing's syndrome	0.003	0.997	0.000
E23 Hypofunction and other disorders of pituitary gland	0.003	0.997	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.002	0.997	0.000
E24.3 Ectopic ACTH syndrome	0.002	0.997	0.000
E24.1 Nelson's syndrome	0.002	0.997	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.003	0.997	0.000
I72.1 Aneurysm of artery of upper extremity	0.003	0.997	0.000
I85.0 Oesophageal varices with bleeding	0.003	0.997	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.997	0.003
S98 Traumatic amputation of ankle and foot	0.000	0.997	0.002
S97 Crushing injury of ankle and foot	0.000	0.997	0.002
S95 Injury of blood vessels at ankle and foot level	0.000	0.997	0.002
S94 Injury of nerves at ankle and foot level	0.000	0.997	0.002
I72.6 Aneurysm and dissection of vertebral artery	0.002	0.997	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.002	0.997	0.000
K61.0 Anal abscess	0.003	0.997	0.000
T43.6 Psychostimulants with abuse potential	0.000	0.997	0.003
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.997	0.003
K12.1 Other forms of stomatitis	0.000	0.997	0.003
E32 Diseases of thymus	0.002	0.997	0.000
E27 Other disorders of adrenal gland	0.003	0.997	0.000
I72.8 Aneurysm of other specified arteries	0.003	0.997	0.000
I85 Oesophageal varices	0.003	0.997	0.000
M70.2 Olecranon bursitis	0.000	0.997	0.002
E20 Hypoparathyroidism	0.002	0.997	0.000
I72.2 Aneurysm of renal artery	0.002	0.997	0.000
S99.7 Multiple injuries of ankle and foot	0.000	0.997	0.002
O20 Haemorrhage in early pregnancy	0.000	0.997	0.003
E23.2 Diabetes insipidus	0.002	0.997	0.000
E26.8 Other hyperaldosteronism	0.002	0.997	0.000
E26.1 Secondary hyperaldosteronism	0.002	0.997	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.997	0.002
T45.0 Antiallergic and antiemetic drugs	0.000	0.997	0.002
Z12.1 Special screening examination for neoplasm of intestinal tract	0.003	0.997	0.000
N71.9 Inflammatory disease of uterus, unspecified	0.000	0.997	0.002
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.997	0.002
G61.1 Serum neuropathy	0.002	0.998	0.000
T40.2 Other opioids	0.000	0.998	0.002
T36 Poisoning by systemic antibiotics	0.000	0.998	0.002
S90.3 Contusion of other and unspecified parts of foot	0.000	0.998	0.002
T45.2 Vitamins, not elsewhere classified	0.000	0.998	0.002
E31 Polyglandular dysfunction	0.002	0.998	0.000
D37.1 Stomach	0.002	0.998	0.000
S42.0 Fracture of clavicle	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.000	0.998	0.002
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.002	0.998	0.000
E23.6 Other disorders of pituitary gland	0.002	0.998	0.000
E27.1 Primary adrenocortical insufficiency	0.002	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.000	0.998	0.002
S90.2 Contusion of toe(s) with damage to nail	0.000	0.998	0.002
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.002
Z90.4 Acquired absence of other parts of digestive tract	0.002	0.998	0.000
G62.1 Alcoholic polyneuropathy	0.002	0.998	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.002	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.000	0.998	0.002
S42.11 Fracture of scapula (open)	0.002	0.998	0.000
G62.2 Polyneuropathy due to other toxic agents	0.002	0.998	0.000
E25 Adrenogenital disorders	0.002	0.998	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.998	0.002
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.998	0.002
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.998	0.002
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.998	0.002
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.998	0.002
T44.0 Anticholinesterase agents	0.000	0.998	0.002
E35 Disorders of endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E30 Disorders of puberty, not elsewhere classified	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.998	0.002
E32.9 Disease of thymus, unspecified	0.002	0.998	0.000
E24.2 Drug-induced Cushing's syndrome	0.002	0.998	0.000
J06 Acute upper respiratory infections of multiple and unspecified sites	0.002	0.998	0.000
S93.4 Sprain and strain of ankle	0.000	0.998	0.002
S93.6 Sprain and strain of other and unspecified parts of foot	0.000	0.998	0.002
S93.5 Sprain and strain of toe(s)	0.000	0.998	0.002
S93.0 Dislocation of ankle joint	0.000	0.998	0.002
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.998	0.002
T45.8 Other primarily systemic and haematological agents	0.000	0.998	0.002
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.998	0.002
T45.6 Fibrinolysis-affecting drugs	0.000	0.998	0.002
T45.4 Iron and its compounds	0.000	0.998	0.002
T45.3 Enzymes, not elsewhere classified	0.000	0.998	0.002
E27.4 Other and unspecified adrenocortical insufficiency	0.002	0.998	0.000
E20.9 Hypoparathyroidism, unspecified	0.002	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.998	0.002
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.002
T37.5 Antiviral drugs	0.000	0.998	0.002
T37.4 Anthelminthics	0.000	0.998	0.002
T37.3 Other antiprotozoal drugs	0.000	0.998	0.002
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.998	0.002
T37.1 Antimycobacterial drugs	0.000	0.998	0.002
T37.0 Sulphonamides	0.000	0.998	0.002
T41.5 Therapeutic gases	0.000	0.998	0.002
T41.4 Anaesthetic, unspecified	0.000	0.998	0.002
T41.3 Local anaesthetics	0.000	0.998	0.002
T41.2 Other and unspecified general anaesthetics	0.000	0.998	0.002
T41.1 Intravenous anaesthetics	0.000	0.998	0.002
T41.0 Inhaled anaesthetics	0.000	0.998	0.002
T49.9 Topical agent, unspecified	0.000	0.998	0.002
T49.8 Other topical agents	0.000	0.998	0.002
T49.7 Dental drugs, topically applied	0.000	0.998	0.002
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.998	0.002
T49.5 Ophthalmological drugs and preparations	0.000	0.998	0.002
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.998	0.002
T49.3 Emollients, demulcents and protectants	0.000	0.998	0.002
T49.2 Local astringents and local detergents	0.000	0.998	0.002
T49.1 Antipruritics	0.000	0.998	0.002
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.998	0.002
S92.70 Multiple fractures of foot (closed)	0.000	0.998	0.002
G47.1 Disorders of excessive somnolence [hypersomnias]	0.000	0.998	0.002
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.002
D37.0 Lip, oral cavity and pharynx	0.002	0.998	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.998	0.002
T48.5 Anti-common-cold drugs	0.000	0.998	0.002
T48.4 Expectorants	0.000	0.998	0.002
T48.3 Antitussives	0.000	0.998	0.002
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.998	0.002
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.998	0.002
T48.0 Oxytocic drugs	0.000	0.998	0.002
E27.3 Drug-induced adrenocortical insufficiency	0.002	0.998	0.000
E34.0 Carcinoid syndrome	0.002	0.998	0.000
J84.0 Alveolar and parietoalveolar conditions	0.000	0.998	0.002
Q54.0 Hypospadias, balanic	0.002	0.998	0.000
W44.9 Unspecified place	0.000	0.998	0.002
W44.5 Trade and service area	0.000	0.998	0.002
W44.7 Farm	0.000	0.998	0.002
W44.6 Industrial and construction area	0.000	0.998	0.002
W44.4 Street and highway	0.000	0.998	0.002
W44.3 Sports and athletics area	0.000	0.998	0.002
W44.2 School, other institution and public administrative area	0.000	0.998	0.002
W44.1 Residential institution	0.000	0.998	0.002
J01.9 Acute sinusitis, unspecified	0.002	0.998	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.002	0.998	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.998	0.002
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.998	0.002
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.998	0.002
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.002	0.998	0.000
E23.1 Drug-induced hypopituitarism	0.002	0.998	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.000	0.998	0.002
S94.9 Injury of unspecified nerve at ankle and foot level	0.000	0.998	0.002
S94.8 Injury of other nerves at ankle and foot level	0.000	0.998	0.002
S94.7 Injury of multiple nerves at ankle and foot level	0.000	0.998	0.002
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.000	0.998	0.002
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.000	0.998	0.002
S94.1 Injury of medial plantar nerve	0.000	0.998	0.002
S94.0 Injury of lateral plantar nerve	0.000	0.998	0.002
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.000	0.998	0.002
S95.8 Injury of other blood vessels at ankle and foot level	0.000	0.998	0.002
S95.7 Injury of multiple blood vessels at ankle and foot level	0.000	0.998	0.002
S95.2 Injury of dorsal vein of foot	0.000	0.998	0.002
S95.1 Injury of plantar artery of foot	0.000	0.998	0.002
S95.0 Injury of dorsal artery of foot	0.000	0.998	0.002
S97.8 Crushing injury of other parts of ankle and foot	0.000	0.998	0.002
S97.1 Crushing injury of toe(s)	0.000	0.998	0.002
S97.0 Crushing injury of ankle	0.000	0.998	0.002
S98.4 Traumatic amputation of foot, level unspecified	0.000	0.998	0.002
S98.3 Traumatic amputation of other parts of foot	0.000	0.998	0.002
S98.2 Traumatic amputation of two or more toes	0.000	0.998	0.002
S98.1 Traumatic amputation of one toe	0.000	0.998	0.002
S98.0 Traumatic amputation of foot at ankle level	0.000	0.998	0.002
T45.5 Anticoagulants	0.000	0.998	0.002
W44.8 Other specified place	0.000	0.998	0.002
E32.8 Other diseases of thymus	0.002	0.998	0.000
E32.1 Abscess of thymus	0.002	0.998	0.000
E32.0 Persistent hyperplasia of thymus	0.002	0.998	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.000	0.998	0.002
E29 Testicular dysfunction	0.002	0.998	0.000
E23.7 Disorder of pituitary gland, unspecified	0.002	0.998	0.000
E27.5 Adrenomedullary hyperfunction	0.002	0.998	0.000
E27.0 Other adrenocortical overactivity	0.002	0.998	0.000
E31.0 Autoimmune polyglandular failure	0.002	0.998	0.000
L93.0 Discoid lupus erythematosus	0.002	0.998	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.000	0.998	0.002
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.998	0.002
M70.29 Olecranon bursitis-Site unspec	0.000	0.998	0.002
M70.28 Olecranon bursitis-Other	0.000	0.998	0.002
M70.27 Olecranon bursitis-Ankle/Foot	0.000	0.998	0.002
M70.26 Olecranon bursitis-Lower Leg	0.000	0.998	0.002
M70.25 Olecranon bursitis-Pelvic/Thigh	0.000	0.998	0.002
M70.24 Olecranon bursitis-Hand	0.000	0.998	0.002
M70.23 Olecranon bursitis-Forearm	0.000	0.998	0.002
M70.21 Olecranon bursitis-Shldr region	0.000	0.998	0.002
M70.20 Olecranon bursitis-Mult sites	0.000	0.998	0.002
E20.8 Other hypoparathyroidism	0.002	0.998	0.000
E20.1 Pseudohypoparathyroidism	0.002	0.998	0.000
E20.0 Idiopathic hypoparathyroidism	0.002	0.998	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations