TreeWAS – Variant ID: rs3809566

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I60-I69 Cerebrovascular diseases	0.000	0.867	0.133
I61 Intracerebral haemorrhage	0.000	0.871	0.129
I63 Cerebral infarction	0.000	0.874	0.126
I69 Sequelae of cerebrovascular disease	0.000	0.875	0.125
I67 Other cerebrovascular diseases	0.000	0.876	0.124
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.877	0.123
H61.2 Impacted cerumen	0.120	0.880	0.000
I67.2 Cerebral atherosclerosis	0.000	0.880	0.120
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.881	0.119
I63.8 Other cerebral infarction	0.000	0.882	0.118
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.884	0.116
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.884	0.116
I67.1 Cerebral aneurysm, nonruptured	0.000	0.885	0.115
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.889	0.111
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.889	0.111
I65.2 Occlusion and stenosis of carotid artery	0.000	0.891	0.109
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.891	0.109
I61.8 Other intracerebral haemorrhage	0.000	0.892	0.108
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.895	0.105
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.895	0.105
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.899	0.101
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.899	0.101
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.900	0.100
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.901	0.098
I60 Subarachnoid haemorrhage	0.000	0.902	0.098
I62 Other nontraumatic intracranial haemorrhage	0.000	0.903	0.097
I69.3 Sequelae of cerebral infarction	0.000	0.904	0.096
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.906	0.094
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.906	0.094
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.907	0.093
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.908	0.092
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.908	0.092
I65.1 Occlusion and stenosis of basilar artery	0.000	0.908	0.092
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.909	0.091
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.909	0.091
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.910	0.090
I67.5 Moyamoya disease	0.000	0.911	0.089
I67.4 Hypertensive encephalopathy	0.000	0.911	0.089
I67.3 Progressive vascular leukoencephalopathy	0.000	0.911	0.089
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.912	0.088
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.912	0.088
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.914	0.086
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.915	0.085
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.916	0.084
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.917	0.083
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.918	0.082
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.918	0.082
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.919	0.081
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.920	0.080
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.920	0.080
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.921	0.079
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.922	0.078
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.925	0.075
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.926	0.074
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.927	0.073
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.927	0.073
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.927	0.073
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.928	0.072
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.929	0.071
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.929	0.071
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.930	0.070
I62.1 Nontraumatic extradural haemorrhage	0.000	0.931	0.069
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.933	0.067
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.933	0.067
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.933	0.067
I68.0 Cerebral amyloid angiopathy	0.000	0.936	0.064
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.938	0.062
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.940	0.060
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.940	0.060
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.952	0.048
I60.8 Other subarachnoid haemorrhage	0.000	0.956	0.043
M25.57 Pain in joint (Ankle and foot)	0.000	0.959	0.041
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.959	0.041
T92 Sequelae of injuries of upper limb	0.036	0.964	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.035	0.965	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.034	0.966	0.000
T92.1 Sequelae of fracture of arm	0.034	0.966	0.000
T92.0 Sequelae of open wound of upper limb	0.032	0.968	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.030	0.970	0.000
H61 Other disorders of external ear	0.030	0.970	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.030	0.970	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.026	0.974	0.000
I67.8 Other specified cerebrovascular diseases	0.000	0.975	0.025
T92.4 Sequelae of injury of nerve of upper limb	0.025	0.975	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.024	0.976	0.000
H61.3 Acquired stenosis of external ear canal	0.023	0.977	0.000
H61.9 Disorder of external ear, unspecified	0.022	0.978	0.000
H61.8 Other specified disorders of external ear	0.018	0.982	0.000
H61.1 Non-infective disorders of pinna	0.016	0.983	0.000
H61.0 Perichondritis of external ear	0.016	0.983	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.986	0.014
K62.7 Radiation proctitis	0.000	0.987	0.013
N76.4 Abscess of vulva	0.000	0.987	0.013
E27.4 Other and unspecified adrenocortical insufficiency	0.010	0.990	0.000
A04.8 Other specified bacterial intestinal infections	0.010	0.990	0.000
I67.9 Cerebrovascular disease, unspecified	0.000	0.991	0.009
H60-H62 Diseases of external ear	0.008	0.992	0.000
N76 Other inflammation of vagina and vulva	0.000	0.994	0.006
H62 Disorders of external ear in diseases classified elsewhere	0.006	0.994	0.000
N76.2 Acute vulvitis	0.000	0.994	0.006
N76.1 Subacute and chronic vaginitis	0.000	0.995	0.005
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.005	0.995	0.000
A87.9 Viral meningitis, unspecified	0.000	0.995	0.005
S62.50 Fracture of thumb (closed)	0.005	0.995	0.000
T95 Sequelae of burns, corrosions and frostbite	0.005	0.995	0.000
N76.3 Subacute and chronic vulvitis	0.000	0.995	0.005
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.005	0.995	0.000
N76.5 Ulceration of vagina	0.000	0.995	0.005
H62.8 Other disorders of external ear in diseases classified elsewhere	0.004	0.995	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.004	0.995	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.004	0.995	0.000
H62.2 Otitis externa in mycoses	0.004	0.995	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.004	0.995	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.000	0.995	0.005
E27 Other disorders of adrenal gland	0.005	0.995	0.000
F52.2 Failure of genital response	0.000	0.996	0.004
N76.0 Acute vaginitis	0.000	0.996	0.004
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.004	0.996	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.000	0.996	0.004
E27.3 Drug-induced adrenocortical insufficiency	0.004	0.996	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.004	0.996	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.004	0.996	0.000
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.004	0.996	0.000
T91 Sequelae of injuries of neck and trunk	0.004	0.996	0.000
G91.9 Hydrocephalus, unspecified	0.000	0.996	0.004
N76.6 Ulceration of vulva	0.000	0.996	0.004
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.004	0.996	0.000
T95.8 Sequelae of other specified burn, corrosion and frostbite	0.004	0.996	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.004	0.996	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.004	0.996	0.000
T95.9 Sequelae of unspecified burn, corrosion and frostbite	0.004	0.996	0.000
T95.4 Sequelae of burn and corrosion classifiable only according to extent of body surface involved	0.004	0.996	0.000
T95.0 Sequelae of burn, corrosion and frostbite of head and neck	0.003	0.996	0.000
H60 Otitis externa	0.004	0.996	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.003	0.996	0.000
I63.9 Cerebral infarction, unspecified	0.000	0.996	0.004
T91.3 Sequelae of injury of spinal cord	0.004	0.996	0.000
E27.8 Other specified disorders of adrenal gland	0.003	0.996	0.000
E27.5 Adrenomedullary hyperfunction	0.003	0.996	0.000
E27.0 Other adrenocortical overactivity	0.003	0.996	0.000
S19.9 Unspecified injury of neck	0.003	0.996	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.997	0.003
F52.0 Lack or loss of sexual desire	0.000	0.997	0.003
E27.1 Primary adrenocortical insufficiency	0.003	0.997	0.000
S05.1 Contusion of eyeball and orbital tissues	0.003	0.997	0.000
S60.8 Other superficial injuries of wrist and hand	0.003	0.997	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.000	0.997	0.003
N42.1 Congestion and haemorrhage of prostate	0.003	0.997	0.000
A87 Viral meningitis	0.000	0.997	0.003
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.003	0.997	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.003	0.997	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.003	0.997	0.000
T95.3 Sequelae of burn, corrosion and frostbite of lower limb	0.003	0.997	0.000
H60.4 Cholesteatoma of external ear	0.003	0.997	0.000
N76.8 Other specified inflammation of vagina and vulva	0.000	0.997	0.003
T98 Sequelae of other and unspecified effects of external causes	0.003	0.997	0.000
H60.3 Other infective otitis externa	0.003	0.997	0.000
O46.9 Antepartum haemorrhage, unspecified	0.000	0.997	0.003
H60.2 Malignant otitis externa	0.003	0.997	0.000
C90.0 Multiple myeloma	0.000	0.997	0.003
S92.50 Fracture of other toe (closed)	0.003	0.997	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.003	0.997	0.000
T94.0 Sequelae of injuries involving multiple body regions	0.003	0.997	0.000
S05.9 Injury of eye and orbit, part unspecified	0.003	0.997	0.000
E27.2 Addisonian crisis	0.003	0.997	0.000
S92.5 Fracture of other toe	0.003	0.997	0.000
S92 Fracture of foot, except ankle	0.003	0.997	0.000
Q89.2 Congenital malformations of other endocrine glands	0.000	0.997	0.003
A87.0 Enteroviral meningitis	0.000	0.997	0.003
H60.5 Acute otitis externa, non-infective	0.003	0.997	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.003	0.997	0.000
S05 Injury of eye and orbit	0.003	0.997	0.000
S92.41 Fracture of great toe (open)	0.003	0.997	0.000
H60.8 Other otitis externa	0.003	0.997	0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.000	0.997	0.002
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.000	0.997	0.002
F52.7 Excessive sexual drive	0.000	0.997	0.002
F52.6 Nonorganic dyspareunia	0.000	0.997	0.002
F52.5 Nonorganic vaginismus	0.000	0.997	0.002
F52.4 Premature ejaculation	0.000	0.997	0.002
F52.3 Orgasmic dysfunction	0.000	0.997	0.002
F52.1 Sexual aversion and lack of sexual enjoyment	0.000	0.997	0.002
H60.1 Cellulitis of external ear	0.003	0.997	0.000
S92.2 Fracture of other tarsal bone(s)	0.003	0.997	0.000
A87.8 Other viral meningitis	0.000	0.997	0.002
A87.1 Adenoviral meningitis	0.000	0.997	0.002
S92.1 Fracture of talus	0.003	0.997	0.000
S99.9 Unspecified injury of ankle and foot	0.003	0.997	0.000
E27.9 Disorder of adrenal gland, unspecified	0.002	0.997	0.000
S92.4 Fracture of great toe	0.003	0.997	0.000
M20.5 Other deformities of toe(s) (acquired)	0.000	0.997	0.003
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.003	0.997	0.000
S19 Other and unspecified injuries of neck	0.003	0.997	0.000
H60.0 Abscess of external ear	0.002	0.997	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.002	0.997	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.002	0.997	0.000
S92.10 Fracture of talus (closed)	0.002	0.997	0.000
S92.3 Fracture of metatarsal bone	0.002	0.997	0.000
T98.2 Sequelae of certain early complications of trauma	0.002	0.997	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.002	0.997	0.000
T91.1 Sequelae of fracture of spine	0.002	0.998	0.000
S82.21 Fracture of shaft of tibia (open)	0.000	0.998	0.002
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.000	0.998	0.002
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.002	0.998	0.000
A87.2 Lymphocytic choriomeningitis	0.000	0.998	0.002
T94.1 Sequelae of injuries, not specified by body region	0.002	0.998	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.002	0.998	0.000
T90 Sequelae of injuries of head	0.002	0.998	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.002	0.998	0.000
S92.9 Fracture of foot, unspecified	0.002	0.998	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.002	0.998	0.000
K05.3 Chronic periodontitis	0.002	0.998	0.000
S99 Other and unspecified injuries of ankle and foot	0.002	0.998	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.000	0.998	0.002
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.002	0.998	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.002	0.998	0.000
S92.51 Fracture of other toe (open)	0.002	0.998	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.002	0.998	0.000
S05.7 Avulsion of eye	0.002	0.998	0.000
M93.9 Osteochondropathy, unspecified	0.000	0.998	0.002
S92.7 Multiple fractures of foot	0.002	0.998	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.002	0.998	0.000
W10.8 Other specified place	0.002	0.998	0.000
S92.11 Fracture of talus (open)	0.002	0.998	0.000
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.000	0.998	0.002
M82.1 Osteoporosis in endocrine disorders	0.000	0.998	0.002
S90-S99 Injuries to the ankle and foot	0.002	0.998	0.000
M91.20 Coxa plana-Mult sites	0.000	0.998	0.002
S19.7 Multiple injuries of neck	0.002	0.998	0.000
T90.9 Sequelae of unspecified injury of head	0.002	0.998	0.000
S19.8 Other specified injuries of neck	0.002	0.998	0.000
T90.1 Sequelae of open wound of head	0.002	0.998	0.000
S92.31 Fracture of metatarsal bone (open)	0.002	0.998	0.000
S62.5 Fracture of thumb	0.002	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.002	0.998	0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.000	0.998	0.002
T90.8 Sequelae of other specified injuries of head	0.002	0.998	0.000
S11 Open wound of neck	0.002	0.998	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.002	0.998	0.000
S80.0 Contusion of knee	0.002	0.998	0.000
S92.91 Fracture of foot, unspecified (open)	0.002	0.998	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.002	0.998	0.000
S99.8 Other specified injuries of ankle and foot	0.002	0.998	0.000
T90.3 Sequelae of injury of cranial nerves	0.002	0.998	0.000
Z29.0 Isolation	0.000	0.998	0.002
S11.9 Open wound of neck, part unspecified	0.002	0.998	0.000
S90.0 Contusion of ankle	0.002	0.998	0.000
S99.7 Multiple injuries of ankle and foot	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.998	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.998	0.002
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.000	0.998	0.002
S80.9 Superficial injury of lower leg, unspecified	0.002	0.998	0.000
S11.8 Open wound of other parts of neck	0.002	0.998	0.000
M87.9 Osteonecrosis, unspecified	0.000	0.998	0.002
S93.3 Dislocation of other and unspecified parts of foot	0.002	0.998	0.000
S80 Superficial injury of lower leg	0.002	0.998	0.000
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.000	0.998	0.002
S61.9 Open wound of wrist and hand, part unspecified	0.002	0.998	0.000
T90.0 Sequelae of superficial injury of head	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
S11.7 Multiple open wounds of neck	0.002	0.998	0.000
G91 Hydrocephalus	0.000	0.998	0.002
M87.96 Osteonecrosis, unspecified (Lower leg)	0.000	0.998	0.002
S92.71 Multiple fractures of foot (open)	0.002	0.998	0.000
E11.2 With renal complications	0.002	0.998	0.000
M91.2 Coxa plana	0.000	0.998	0.002
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.000	0.998	0.002
M82.18 Osteoporosis in endocrine disorders (Other)	0.000	0.998	0.002
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.000	0.998	0.002
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.000	0.998	0.002
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.000	0.998	0.002
M82.14 Osteoporosis in endocrine disorders (Hand)	0.000	0.998	0.002
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.000	0.998	0.002
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.000	0.998	0.002
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.000	0.998	0.002
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.000	0.998	0.002
S92.40 Fracture of great toe (closed)	0.002	0.998	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.000	0.998	0.002
S95 Injury of blood vessels at ankle and foot level	0.002	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.998	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.002	0.998	0.000
W94.8 Other specified place	0.000	0.998	0.002
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
S98 Traumatic amputation of ankle and foot	0.002	0.998	0.000
S10-S19 Injuries to the neck	0.002	0.998	0.000
M94.89 Other specified disorders of cartilage (Site unspecified)	0.000	0.998	0.002
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.002	0.998	0.000
S97 Crushing injury of ankle and foot	0.002	0.998	0.000
G80.9 Infantile cerebral palsy, unspecified	0.002	0.998	0.000
S14 Injury of nerves and spinal cord at neck level	0.002	0.998	0.000
H21.8 Other specified disorders of iris and ciliary body	0.000	0.998	0.002
Q89 Other congenital malformations, not elsewhere classified	0.000	0.998	0.002
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.002	0.998	0.000
J02.9 Acute pharyngitis, unspecified	0.000	0.998	0.002
Q85.8 Other phakomatoses, not elsewhere classified	0.000	0.998	0.002
S11.2 Open wound involving pharynx and cervical oesophagus	0.002	0.998	0.000
S11.1 Open wound involving thyroid gland	0.002	0.998	0.000
S11.0 Open wound involving larynx and trachea	0.002	0.998	0.000
S80.7 Multiple superficial injuries of lower leg	0.002	0.998	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.998	0.000
T90.4 Sequelae of injury of eye and orbit	0.002	0.998	0.000
A80-A89 Viral infections of the central nervous system	0.000	0.998	0.002
M87.98 Osteonecrosis, unspecified (Other)	0.000	0.998	0.002
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
G91.8 Other hydrocephalus	0.000	0.998	0.002
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.001	0.998	0.001
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.000	0.998	0.002
S92.70 Multiple fractures of foot (closed)	0.001	0.998	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.000	0.998	0.002
S14.1 Other and unspecified injuries of cervical spinal cord	0.002	0.998	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.002	0.998	0.000
M90.7 Fracture of bone in neoplastic disease	0.000	0.998	0.002
S90.8 Other superficial injuries of ankle and foot	0.002	0.998	0.000
M93 Other osteochondropathies	0.000	0.998	0.002
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.000	0.998	0.002
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.000	0.998	0.002
M33.2 Polymyositis	0.002	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.001	0.998	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.000	0.998	0.001
M87.94 Osteonecrosis, unspecified (Hand)	0.000	0.998	0.001
M87.93 Osteonecrosis, unspecified (Forearm)	0.000	0.998	0.001
M87.92 Osteonecrosis, unspecified (Upper arm)	0.000	0.998	0.001
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.000	0.998	0.001
S14.3 Injury of brachial plexus	0.002	0.998	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.001	0.998	0.000
Q85 Phakomatoses, not elsewhere classified	0.000	0.998	0.002
S90.7 Multiple superficial injuries of ankle and foot	0.001	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.001	0.998	0.000
S93.4 Sprain and strain of ankle	0.001	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.001	0.998	0.000
T19.1 Foreign body in bladder	0.000	0.998	0.002
A81 Atypical virus infections of central nervous system	0.000	0.998	0.002
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.002	0.998	0.000
D75.1 Secondary polycythaemia	0.000	0.998	0.002
G91.1 Obstructive hydrocephalus	0.000	0.998	0.002
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.001	0.998	0.000
M91.29 Coxa plana-Site unspec	0.000	0.998	0.001
M91.28 Coxa plana-Other	0.000	0.998	0.001
M91.27 Coxa plana-Ankle/Foot	0.000	0.998	0.001
M91.26 Coxa plana-Lower Leg	0.000	0.998	0.001
M91.25 Coxa plana-Pelvic/Thigh	0.000	0.998	0.001
M91.24 Coxa plana-Hand	0.000	0.998	0.001
M91.23 Coxa plana-Forearm	0.000	0.998	0.001
M91.22 Coxa plana-Upper arm	0.000	0.998	0.001
M91.21 Coxa plana-Shldr region	0.000	0.998	0.001
L92.1 Necrobiosis lipoidica, not elsewhere classified	0.000	0.998	0.001
M94.8 Other specified disorders of cartilage	0.000	0.998	0.002
S93.2 Rupture of ligaments at ankle and foot level	0.001	0.998	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.000	0.998	0.001
M90.78 Fracture of bone in neoplastic disease (Other)	0.000	0.998	0.002
M92.7 Juvenile osteochondrosis of metatarsus	0.000	0.998	0.001
Q85.9 Phakomatosis, unspecified	0.000	0.998	0.001
S93.1 Dislocation of toe(s)	0.001	0.998	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.001	0.998	0.000
S94.8 Injury of other nerves at ankle and foot level	0.001	0.998	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.001	0.998	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.001	0.998	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.001	0.998	0.000
S94.1 Injury of medial plantar nerve	0.001	0.998	0.000
S94.0 Injury of lateral plantar nerve	0.001	0.998	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.001	0.998	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.001	0.998	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.001	0.998	0.000
S95.2 Injury of dorsal vein of foot	0.001	0.998	0.000
S95.1 Injury of plantar artery of foot	0.001	0.998	0.000
S95.0 Injury of dorsal artery of foot	0.001	0.998	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.001	0.998	0.000
S98.3 Traumatic amputation of other parts of foot	0.001	0.998	0.000
S98.2 Traumatic amputation of two or more toes	0.001	0.998	0.000
S98.0 Traumatic amputation of foot at ankle level	0.001	0.998	0.000
T02.4 Fractures involving multiple regions of both upper limbs	0.000	0.998	0.001
S17 Crushing injury of neck	0.001	0.998	0.000
S15 Injury of blood vessels at neck level	0.001	0.998	0.000
S10 Superficial injury of neck	0.002	0.998	0.000
S18 Traumatic amputation at neck level	0.001	0.998	0.000
S16 Injury of muscle and tendon at neck level	0.001	0.998	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.001	0.998	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.001	0.998	0.000
N81.5 Vaginal enterocele	0.000	0.998	0.002
S14.6 Injury of other and unspecified nerves of neck	0.001	0.998	0.000
S14.5 Injury of cervical sympathetic nerves	0.001	0.998	0.000
S14.4 Injury of peripheral nerves of neck	0.001	0.998	0.000
S14.2 Injury of nerve root of cervical spine	0.001	0.998	0.000
S14.0 Concussion and oedema of cervical spinal cord	0.001	0.998	0.000
S97.0 Crushing injury of ankle	0.001	0.998	0.000
S98.1 Traumatic amputation of one toe	0.001	0.998	0.000
A81.0 Creutzfeldt-Jakob disease	0.000	0.998	0.001
C44.1 Skin of eyelid, including canthus	0.002	0.998	0.000
G91.2 Normal-pressure hydrocephalus	0.000	0.998	0.001
S05.8 Other injuries of eye and orbit	0.001	0.998	0.000
S82.2 Fracture of shaft of tibia	0.000	0.998	0.002
M79.70 Fibromyalgia (Multiple sites)	0.000	0.998	0.002
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.000	0.998	0.001
G91.3 Posttraumatic hydrocephalus, unspecified	0.000	0.998	0.001
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.000	0.998	0.001
Q89.9 Congenital malformation, unspecified	0.000	0.998	0.001
Q89.8 Other specified congenital malformations	0.000	0.998	0.001
Q89.7 Multiple congenital malformations, not elsewhere classified	0.000	0.998	0.001
Q89.4 Conjoined twins	0.000	0.998	0.001
Q89.1 Congenital malformations of adrenal gland	0.000	0.998	0.001
A86 Unspecified viral encephalitis	0.000	0.998	0.001
M92 Other juvenile osteochondrosis	0.000	0.998	0.001
E23.7 Disorder of pituitary gland, unspecified	0.001	0.998	0.000
S92.0 Fracture of calcaneus	0.001	0.998	0.000
A88 Other viral infections of central nervous system, not elsewhere classified	0.000	0.998	0.001
A85 Other viral encephalitis, not elsewhere classified	0.000	0.998	0.001
A84 Tick-borne viral encephalitis	0.000	0.998	0.001
A83 Mosquito-borne viral encephalitis	0.000	0.998	0.001
A82 Rabies	0.000	0.998	0.001
A80 Acute poliomyelitis	0.000	0.998	0.001
A91 Dengue haemorrhagic fever	0.000	0.998	0.001
A90 Dengue fever [classical dengue]	0.000	0.998	0.001
A89 Unspecified viral infection of central nervous system	0.000	0.998	0.001
T93 Sequelae of injuries of lower limb	0.002	0.998	0.000
S62.51 Fracture of thumb (open)	0.001	0.998	0.000
S10.8 Superficial injury of other parts of neck	0.001	0.998	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.001	0.999	0.000
S82.20 Fracture of shaft of tibia (closed)	0.000	0.999	0.001
G97.8 Other postprocedural disorders of nervous system	0.001	0.999	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.001	0.999	0.000
M93.8 Other specified osteochondropathies	0.000	0.999	0.001
M93.2 Osteochondritis dissecans	0.000	0.999	0.001
M93.0 Slipped upper femoral epiphysis (nontraumatic)	0.000	0.999	0.001
S97.1 Crushing injury of toe(s)	0.001	0.999	0.000
T90.5 Sequelae of intracranial injury	0.001	0.999	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.999	0.001
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.000	0.999	0.001
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.000	0.999	0.001
M90.74 Fracture of bone in neoplastic disease (Hand)	0.000	0.999	0.001
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.000	0.999	0.001
M94.88 Other specified disorders of cartilage (Other)	0.000	0.999	0.001
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.000	0.999	0.001
G91.0 Communicating hydrocephalus	0.000	0.999	0.001
H49.0 Third [oculomotor] nerve palsy	0.000	0.999	0.001
L92.0 Granuloma annulare	0.000	0.999	0.001
M87.2 Osteonecrosis due to previous trauma	0.000	0.999	0.001
M92.2 Juvenile osteochondrosis of hand	0.000	0.999	0.001
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.001	0.999	0.000
E23.0 Hypopituitarism	0.001	0.999	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.001	0.999	0.000
S93.40 Sprain of unspecified ligament of ankle	0.001	0.999	0.000
A81.9 Atypical virus infection of central nervous system, unspecified	0.000	0.999	0.001
A81.8 Other atypical virus infections of central nervous system	0.000	0.999	0.001
A81.2 Progressive multifocal leukoencephalopathy	0.000	0.999	0.001
A81.1 Subacute sclerosing panencephalitis	0.000	0.999	0.001
Q85.1 Tuberous sclerosis	0.000	0.999	0.001
Q89.3 Situs inversus	0.000	0.999	0.001
Q89.0 Congenital malformations of spleen	0.000	0.999	0.001
S93.6 Sprain and strain of other and unspecified parts of foot	0.001	0.999	0.000
E23 Hypofunction and other disorders of pituitary gland	0.001	0.999	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.001	0.999	0.000
M94 Other disorders of cartilage	0.000	0.999	0.001
M94.08 Chondrocostal junction syndrome [Tietze]-Other	0.000	0.999	0.001
M94.84 Other specified disorders of cartilage (Hand)	0.000	0.999	0.001
M94.83 Other specified disorders of cartilage (Forearm)	0.000	0.999	0.001
M94.82 Other specified disorders of cartilage (Upper arm)	0.000	0.999	0.001
M94.80 Other specified disorders of cartilage (Multiple sites)	0.000	0.999	0.001
D25.2 Subserosal leiomyoma of uterus	0.000	0.999	0.001
H57.0 Anomalies of pupillary function	0.001	0.999	0.000
M91.9 Juvenile osteochondrosis of hip and pelvis, unspecified	0.000	0.999	0.001
M91.8 Other juvenile osteochondrosis of hip and pelvis	0.000	0.999	0.001
M91.3 Pseudocoxalgia	0.000	0.999	0.001
M91.0 Juvenile osteochondrosis of pelvis	0.000	0.999	0.001
S90.3 Contusion of other and unspecified parts of foot	0.001	0.999	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.001	0.999	0.000
S91 Open wound of ankle and foot	0.001	0.999	0.000
M91-M94 Chondropathies	0.000	0.999	0.001
T02.41 Fractures involving multiple regions of both upper limbs (open)	0.000	0.999	0.001
K72.9 Hepatic failure, unspecified	0.000	0.999	0.001
M94.0 Chondrocostal junction syndrome [Tietze]	0.000	0.999	0.001
S10.9 Superficial injury of neck, part unspecified	0.001	0.999	0.000
S10.7 Multiple superficial injuries of neck	0.001	0.999	0.000
S10.0 Contusion of throat	0.001	0.999	0.000
S15.9 Injury of unspecified blood vessel at neck level	0.001	0.999	0.000
S15.8 Injury of other blood vessels at neck level	0.001	0.999	0.000
S15.7 Injury of multiple blood vessels at neck level	0.001	0.999	0.000
S15.3 Injury of internal jugular vein	0.001	0.999	0.000
S15.2 Injury of external jugular vein	0.001	0.999	0.000
S15.1 Injury of vertebral artery	0.001	0.999	0.000
S15.0 Injury of carotid artery	0.001	0.999	0.000
S17.9 Crushing injury of neck, part unspecified	0.001	0.999	0.000
S17.8 Crushing injury of other parts of neck	0.001	0.999	0.000
S17.0 Crushing injury of larynx and traches	0.001	0.999	0.000
M87 Osteonecrosis	0.000	0.999	0.001
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.000	0.999	0.001
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.000	0.999	0.001
M23.3 Other meniscus derangements	0.001	0.999	0.000
N11.1 Chronic obstructive pyelonephritis	0.000	0.999	0.001
S00.8 Superficial injury of other parts of head	0.001	0.999	0.000
N11 Chronic tubulo-interstitial nephritis	0.000	0.999	0.001
M25.37 Other instability of joint (Ankle and foot)	0.000	0.999	0.001
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.000	0.999	0.001
M94.86 Other specified disorders of cartilage (Lower leg)	0.000	0.999	0.001
G80.8 Other infantile cerebral palsy	0.001	0.999	0.000
M92.5 Juvenile osteochondrosis of tibia and fibula	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations