TreeWAS – Variant ID: rs3811273

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D05.1 Intraductal carcinoma in situ	0.015	0.985	0.000
E89.0 Postprocedural hypothyroidism	0.012	0.988	0.000
I25.2 Old myocardial infarction	0.010	0.990	0.000
D05 Carcinoma in situ of breast	0.008	0.992	0.000
E16.2 Hypoglycaemia, unspecified	0.007	0.993	0.000
O32.1 Maternal care for breech presentation	0.007	0.993	0.000
E10 Insulin-dependent diabetes mellitus	0.007	0.993	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.007	0.993	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.007	0.993	0.000
E10.1 With ketoacidosis	0.007	0.993	0.000
E10.3 With ophthalmic complications	0.007	0.993	0.000
E10.4 With neurological complications	0.007	0.993	0.000
E10.8 With unspecified complications	0.006	0.994	0.000
E14.3 With ophthalmic complications	0.006	0.994	0.000
E16 Other disorders of pancreatic internal secretion	0.006	0.994	0.000
D05.7 Other carcinoma in situ of breast	0.006	0.994	0.000
M79.62 Pain in limb (Upper arm)	0.006	0.994	0.000
E10.9 Without complications	0.006	0.994	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.006	0.994	0.000
E10.0 With coma	0.006	0.994	0.000
E10.6 With other specified complications	0.006	0.994	0.000
E14 Unspecified diabetes mellitus	0.006	0.994	0.000
E89.3 Postprocedural hypopituitarism	0.005	0.994	0.000
E10.7 With multiple complications	0.005	0.994	0.000
D05.0 Lobular carcinoma in situ	0.005	0.995	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.005	0.995	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.005	0.995	0.000
E89.5 Postprocedural testicular hypofunction	0.005	0.995	0.000
E89.4 Postprocedural ovarian failure	0.005	0.995	0.000
E89.1 Postprocedural hypoinsulinaemia	0.005	0.995	0.000
E10.2 With renal complications	0.005	0.995	0.000
E10-E14 Diabetes mellitus	0.005	0.995	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.005	0.995	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.005	0.995	0.000
E89.2 Postprocedural hypoparathyroidism	0.005	0.995	0.000
E10.5 With peripheral circulatory complications	0.005	0.995	0.000
E16.1 Other hypoglycaemia	0.005	0.995	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.004	0.995	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.004	0.995	0.000
E16.4 Abnormal secretion of gastrin	0.004	0.995	0.000
E16.3 Increased secretion of glucagon	0.004	0.995	0.000
O32.2 Maternal care for transverse and oblique lie	0.005	0.995	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.004	0.995	0.000
I25 Chronic ischaemic heart disease	0.004	0.996	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.000	0.996	0.004
O32.9 Maternal care for malpresentation of foetus, unspecified	0.004	0.996	0.000
O32.0 Maternal care for unstable lie	0.004	0.996	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.004	0.996	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.004	0.996	0.000
E14.8 With unspecified complications	0.004	0.996	0.000
E14.7 With multiple complications	0.004	0.996	0.000
E14.6 With other specified complications	0.004	0.996	0.000
E14.5 With peripheral circulatory complications	0.004	0.996	0.000
E14.4 With neurological complications	0.004	0.996	0.000
E14.2 Withrenal complications	0.004	0.996	0.000
E14.1 With ketoacidosis	0.004	0.996	0.000
E14.0 With coma	0.004	0.996	0.000
E14.9 Without complications	0.004	0.996	0.000
Z50.1 Other physical therapy	0.004	0.996	0.000
R21 Rash and other nonspecific skin eruption	0.000	0.996	0.004
E12 Malnutrition-related diabetes mellitus	0.004	0.996	0.000
O32.6 Maternal care for compound presentation	0.004	0.996	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.004	0.996	0.000
O32.3 Maternal care for face, brow and chin presentation	0.004	0.996	0.000
O32.4 Maternal care for high head at term	0.004	0.996	0.000
R56.8 Other and unspecified convulsions	0.000	0.996	0.004
E05 Thyrotoxicosis [hyperthyroidism]	0.004	0.996	0.000
I25.3 Aneurysm of heart	0.004	0.996	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.004	0.996	0.000
E13 Other specified diabetes mellitus	0.004	0.996	0.000
E05.9 Thyrotoxicosis, unspecified	0.004	0.996	0.000
I25.5 Ischaemic cardiomyopathy	0.004	0.996	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.996	0.004
O32.8 Maternal care for other malpresentation of foetus	0.003	0.996	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.003	0.996	0.000
E15 Nondiabetic hypoglycaemic coma	0.003	0.996	0.000
I25.6 Silent myocardial ischaemia	0.003	0.997	0.000
M79.6 Pain in limb	0.003	0.997	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.997	0.003
Chapter IV Endocrine, nutritional and metabolic diseases	0.003	0.997	0.000
E05.8 Other thyrotoxicosis	0.003	0.997	0.000
M79.69 Pain in limb (Site unspecified)	0.003	0.997	0.000
S72.30 Fracture of shaft of femur (closed)	0.003	0.997	0.000
I25.4 Coronary artery aneurysm	0.003	0.997	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.997	0.003
M79.61 Pain in limb (Shoulder region)	0.003	0.997	0.000
E40-E46 Malnutrition	0.003	0.997	0.000
E87.6 Hypokalaemia	0.000	0.997	0.003
E46 Unspecified protein-energy malnutrition	0.003	0.997	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.000	0.997	0.003
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.997	0.003
E12.9 Without complications	0.003	0.997	0.000
E12.8 With unspecified complications	0.003	0.997	0.000
E12.7 With multiple complications	0.003	0.997	0.000
E12.6 With other specified complications	0.003	0.997	0.000
E12.5 With peripheral circulatory complications	0.003	0.997	0.000
E12.4 With neurological complications	0.003	0.997	0.000
E12.3 With ophthalmic complications	0.003	0.997	0.000
E12.2 With renal complications	0.003	0.997	0.000
E12.1 With ketoacidosis	0.003	0.997	0.000
E12.0 With coma	0.003	0.997	0.000
K65.9 Peritonitis, unspecified	0.003	0.997	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.997	0.003
R22.9 Localised swelling, mass and lump, unspecified	0.000	0.997	0.003
Z50 Care involving use of rehabilitation procedures	0.003	0.997	0.000
G35 Multiple sclerosis	0.003	0.997	0.000
M79.63 Pain in limb (Forearm)	0.003	0.997	0.000
E05.5 Thyroid crisis or storm	0.003	0.997	0.000
E05.4 Thyrotoxicosis factitia	0.003	0.997	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.003	0.997	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.003	0.997	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.003	0.997	0.000
R22.1 Localised swelling, mass and lump, neck	0.000	0.997	0.003
S72.20 Subtrochanteric fracture (closed)	0.003	0.997	0.000
E13.8 With unspecified complications	0.003	0.997	0.000
E13.7 With multiple complications	0.003	0.997	0.000
E13.6 With other specified complications	0.003	0.997	0.000
E13.5 With peripheral circulatory complications	0.003	0.997	0.000
E13.4 With neurological complications	0.003	0.997	0.000
E13.3 With ophthalmic complications	0.003	0.997	0.000
E13.2 With renal complications	0.003	0.997	0.000
E13.1 With ketoacidosis	0.003	0.997	0.000
E13.0 With coma	0.003	0.997	0.000
M81.9 Osteoporosis, unspecified	0.000	0.997	0.003
Z50.4 Psychotherapy, not elsewhere classified	0.003	0.997	0.000
Z50.5 Speech therapy	0.003	0.997	0.000
S72.3 Fracture of shaft of femur	0.003	0.997	0.000
K92.1 Melaena	0.003	0.997	0.000
S72.10 Pertrochanteric fracture (closed)	0.003	0.997	0.000
E00-E07 Disorders of thyroid gland	0.003	0.997	0.000
M79.68 Pain in limb (Other)	0.003	0.997	0.000
M79.60 Pain in limb (Multiple sites)	0.003	0.997	0.000
S72.2 Subtrochanteric fracture	0.003	0.997	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.003	0.997	0.000
I42.0 Dilated cardiomyopathy	0.000	0.997	0.003
S72.1 Pertrochanteric fracture	0.003	0.997	0.000
E13.9 Without complications	0.002	0.997	0.000
M79.64 Pain in limb (Hand)	0.003	0.997	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.003	0.997	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.002	0.997	0.000
E45 Retarded development following protein-energy malnutrition	0.002	0.997	0.000
E43 Unspecified severe protein-energy malnutrition	0.002	0.997	0.000
E42 Marasmic kwashiorkor	0.002	0.997	0.000
E41 Nutritional marasmus	0.002	0.997	0.000
E40 Kwashiorkor	0.002	0.997	0.000
R22.7 Localised swelling, mass and lump, multiple sites	0.000	0.997	0.002
S72 Fracture of femur	0.003	0.997	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.997	0.002
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.997	0.002
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.997	0.002
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.002
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.997	0.002
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.997	0.002
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.997	0.002
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.997	0.002
Z50.6 Orthoptic training	0.002	0.997	0.000
Z50.3 Drug rehabilitation	0.002	0.997	0.000
D59.1 Other autoimmune haemolytic anaemias	0.002	0.997	0.000
R22.0 Localised swelling, mass and lump, head	0.000	0.998	0.002
S62.60 Fracture of other finger (closed)	0.002	0.998	0.000
Z50.2 Alcohol rehabilitation	0.002	0.998	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.998	0.002
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.998	0.002
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.998	0.002
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.998	0.002
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.998	0.002
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.998	0.002
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.998	0.002
D59 Acquired haemolytic anaemia	0.002	0.998	0.000
D58 Other hereditary haemolytic anaemias	0.002	0.998	0.000
E50-E64 Other nutritional deficiencies	0.002	0.998	0.000
S72.31 Fracture of shaft of femur (open)	0.002	0.998	0.000
E70-E90 Metabolic disorders	0.002	0.998	0.000
M79.65 Pain in limb (Pelvic region and thigh)	0.002	0.998	0.000
M79.67 Pain in limb (Ankle and foot)	0.002	0.998	0.000
Z50.8 Care involving use of rehabilitation procedures	0.002	0.998	0.000
G51.0 Bell's palsy	0.002	0.998	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.998	0.000
E00 Congenital iodine-deficiency syndrome	0.002	0.998	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.002	0.998	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.002	0.998	0.000
S72.21 Subtrochanteric fracture (open)	0.002	0.998	0.000
H53.8 Other visual disturbances	0.002	0.998	0.000
E07 Other disorders of thyroid	0.002	0.998	0.000
M81.98 Osteoporosis, unspecified (Other)	0.000	0.998	0.002
S72.11 Pertrochanteric fracture (open)	0.002	0.998	0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.000	0.998	0.002
D59.9 Acquired haemolytic anaemia, unspecified	0.002	0.998	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
S72.4 Fracture of lower end of femur	0.002	0.998	0.000
E44.1 Mild protein-energy malnutrition	0.002	0.998	0.000
E44.0 Moderate protein-energy malnutrition	0.002	0.998	0.000
R22.2 Localised swelling, mass and lump, trunk	0.000	0.998	0.002
T91.1 Sequelae of fracture of spine	0.002	0.998	0.000
S72.9 Fracture of femur, part unspecified	0.002	0.998	0.000
S72.8 Fractures of other parts of femur	0.002	0.998	0.000
S72.7 Multiple fractures of femur	0.002	0.998	0.000
M80 Osteoporosis with pathological fracture	0.000	0.998	0.002
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.998	0.002
D58.0 Hereditary spherocytosis	0.002	0.998	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.002	0.998	0.000
D55-D59 Haemolytic anaemias	0.002	0.998	0.000
T91 Sequelae of injuries of neck and trunk	0.002	0.998	0.000
K92.2 Gastro-intestinal haemorrhage, unspecified	0.002	0.998	0.000
D70 Agranulocytosis	0.002	0.998	0.000
E53 Deficiency of other B group vitamins	0.002	0.998	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.000	0.998	0.002
D58.8 Other specified hereditary haemolytic anaemias	0.002	0.998	0.000
D58.2 Other haemoglobinopathies	0.002	0.998	0.000
D58.1 Hereditary elliptocytosis	0.002	0.998	0.000
D59.8 Other acquired haemolytic anaemias	0.002	0.998	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.002	0.998	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.002	0.998	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.002	0.998	0.000
D59.3 Haemolytic-uraemic syndrome	0.002	0.998	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.002	0.998	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.002	0.998	0.000
D75.2 Essential thrombocytosis	0.002	0.998	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.002	0.998	0.000
E63 Other nutritional deficiencies	0.002	0.998	0.000
E56 Other vitamin deficiencies	0.002	0.998	0.000
E51 Thiamine deficiency	0.002	0.998	0.000
E50 Vitamin A deficiency	0.002	0.998	0.000
E60 Dietary zinc deficiency	0.002	0.998	0.000
E59 Dietary selenium deficiency	0.002	0.998	0.000
E58 Dietary calcium deficiency	0.002	0.998	0.000
E54 Ascorbic acid deficiency	0.002	0.998	0.000
E52 Niacin deficiency [pellagra]	0.002	0.998	0.000
H02.3 Blepharochalasis	0.000	0.998	0.002
N32.9 Bladder disorder, unspecified	0.000	0.998	0.002
M81 Osteoporosis without pathological fracture	0.000	0.998	0.002
C91.1 Chronic lymphocytic leukaemia	0.002	0.998	0.000
E88 Other metabolic disorders	0.002	0.998	0.000
E84 Cystic fibrosis	0.002	0.998	0.000
E79 Disorders of purine and pyrimidine metabolism	0.002	0.998	0.000
E77 Disorders of glycoprotein metabolism	0.002	0.998	0.000
E76 Disorders of glycosaminoglycan metabolism	0.002	0.998	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.002	0.998	0.000
E74 Other disorders of carbohydrate metabolism	0.002	0.998	0.000
E72 Other disorders of amino-acid metabolism	0.002	0.998	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.002	0.998	0.000
E70 Disorders of aromatic amino-acid metabolism	0.002	0.998	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.002	0.998	0.000
K92 Other diseases of digestive system	0.002	0.998	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.002	0.998	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.002	0.998	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.002	0.998	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.002	0.998	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.998	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.002	0.998	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.002	0.998	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.002	0.998	0.000
E53.9 Vitamin B deficiency, unspecified	0.002	0.998	0.000
E80.4 Gilbert's syndrome	0.002	0.998	0.000
I45.6 Preexcitation syndrome	0.002	0.998	0.000
F03 Unspecified dementia	0.000	0.998	0.002
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.002	0.998	0.000
E07.8 Other specified disorders of thyroid	0.002	0.998	0.000
J47 Bronchiectasis	0.000	0.998	0.002
E07.1 Dyshormogenetic goitre	0.002	0.998	0.000
E07.0 Hypersecretion of calcitonin	0.002	0.998	0.000
K91.4 Colostomy and enterostomy malfunction	0.002	0.998	0.000
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.002	0.998	0.000
D75 Other diseases of blood and blood-forming organs	0.002	0.998	0.000
K50.9 Crohn's disease, unspecified	0.002	0.998	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.002	0.998	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.002	0.998	0.000
E04.2 Non-toxic multinodular goitre	0.002	0.998	0.000
T91.3 Sequelae of injury of spinal cord	0.002	0.998	0.000
E04 Other non-toxic goitre	0.002	0.998	0.000
E55 Vitamin D deficiency	0.002	0.998	0.000
E65-E68 Obesity and other hyperalimentation	0.002	0.998	0.000
S72.40 Fracture of lower end of femur (closed)	0.002	0.998	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.002	0.998	0.000
M79.66 Pain in limb (Lower leg)	0.002	0.998	0.000
S72.41 Fracture of lower end of femur (open)	0.002	0.998	0.000
C82.0 Small cleaved cell, follicular	0.002	0.998	0.000
Z48.8 Other specified surgical follow-up care	0.000	0.998	0.002
S72.71 Multiple fractures of femur (open)	0.002	0.998	0.000
S72.70 Multiple fractures of femur (closed)	0.002	0.998	0.000
S72.81 Fractures of other parts of femur (open)	0.002	0.998	0.000
S72.80 Fractures of other parts of femur (closed)	0.002	0.998	0.000
S72.91 Fracture of femur, part unspecified (open)	0.002	0.998	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.002	0.998	0.000
E83.5 Disorders of calcium metabolism	0.002	0.998	0.000
M80.8 Other osteoporosis with pathological fracture	0.000	0.998	0.002
M80.4 Drug-induced osteoporosis with pathological fracture	0.000	0.998	0.002
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.000	0.998	0.002
M80.2 Osteoporosis of disuse with pathological fracture	0.000	0.998	0.002
Z50.0 Cardiac rehabilitation	0.002	0.998	0.000
E85 Amyloidosis	0.002	0.998	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.000	0.998	0.002
E80.7 Disorder of bilirubin metabolism, unspecified	0.002	0.998	0.000
E80.6 Other disorders of bilirubin metabolism	0.002	0.998	0.000
E80.5 Crigler-Najjar syndrome	0.002	0.998	0.000
E80.3 Defects of catalase and peroxydase	0.002	0.998	0.000
E80.2 Other porphyria	0.002	0.998	0.000
E80.1 Porphyria cutanea tarda	0.002	0.998	0.000
E80.0 Hereditary erythropoietic porphyria	0.002	0.998	0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.002	0.998	0.000
D57 Sickle-cell disorders	0.002	0.998	0.000
D56 Thalassaemia	0.002	0.998	0.000
D55 Anaemia due to enzyme disorders	0.002	0.998	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.998	0.002
T91.9 Sequelae of unspecified injury of neck and trunk	0.002	0.998	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.002	0.998	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.002	0.998	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.002	0.998	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.002	0.998	0.000
E53.1 Pyridoxine deficiency	0.002	0.998	0.000
E53.0 Riboflavin deficiency	0.002	0.998	0.000
E06 Thyroiditis	0.002	0.998	0.000
E73 Lactose intolerance	0.002	0.998	0.000
M10.99 Gout, unspecified (Site unspecified)	0.002	0.998	0.000
E07.9 Disorder of thyroid, unspecified	0.002	0.998	0.000
H81.0 Meniere's disease	0.000	0.998	0.002
L81.4 Other melanin hyperpigmentation	0.002	0.998	0.000
D73 Diseases of spleen	0.002	0.998	0.000
C82.2 Large cell, follicular	0.002	0.998	0.000
D76.3 Other histiocytosis syndromes	0.002	0.998	0.000
H60.9 Otitis externa, unspecified	0.002	0.998	0.000
R56 Convulsions, not elsewhere classified	0.000	0.998	0.002
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.001
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.000	0.998	0.001
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.001
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.001
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.001
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.000	0.998	0.001
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.001
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.001
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.001
D73.4 Cyst of spleen	0.002	0.998	0.000
E50.9 Vitamin A deficiency, unspecified	0.001	0.998	0.000
E50.8 Other manifestations of vitamin A deficiency	0.001	0.998	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.001	0.998	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.001	0.998	0.000
E50.5 Vitamin A deficiency with night blindness	0.001	0.998	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.001	0.998	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.001	0.998	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.001	0.998	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.001	0.998	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.001	0.998	0.000
E51.9 Thiamine deficiency, unspecified	0.001	0.998	0.000
E51.8 Other manifestations of thiamine deficiency	0.001	0.998	0.000
E51.2 Wernicke's encephalopathy	0.001	0.998	0.000
E51.1 Beriberi	0.001	0.998	0.000
E56.9 Vitamin deficiency, unspecified	0.001	0.998	0.000
E56.8 Deficiency of other vitamins	0.001	0.998	0.000
E56.1 Deficiency of vitamin K	0.001	0.998	0.000
E56.0 Deficiency of vitamin E	0.001	0.998	0.000
E63.9 Nutritional deficiency, unspecified	0.001	0.998	0.000
E63.8 Other specified nutritional deficiencies	0.001	0.998	0.000
E63.1 Imbalance of constituents of food intake	0.001	0.998	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.001	0.998	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.001	0.998	0.000
E64.8 Sequelae of other nutritional deficiencies	0.001	0.998	0.000
E64.3 Sequelae of rickets	0.001	0.998	0.000
E64.2 Sequelae of vitamin C deficiency	0.001	0.998	0.000
E64.1 Sequelae of vitamin A deficiency	0.001	0.998	0.000
E64.0 Sequelae of protein-energy malnutrition	0.001	0.998	0.000
O47.0 False labour before 37 completed weeks of gestation	0.002	0.998	0.000
T92.0 Sequelae of open wound of upper limb	0.002	0.998	0.000
K50.0 Crohn's disease of small intestine	0.002	0.998	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.998	0.001
M81.8 Other osteoporosis	0.000	0.998	0.001
M81.6 Localised osteoporosis [Lequesne]	0.000	0.998	0.001
M81.5 Idiopathic osteoporosis	0.000	0.998	0.001
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.998	0.001
M81.2 Osteoporosis of disuse	0.000	0.998	0.001
M81.1 Postoophorectomy osteoporosis	0.000	0.998	0.001
M81.0 Postmenopausal osteoporosis	0.000	0.998	0.001
E61 Deficiency of other nutrient elements	0.001	0.998	0.000
N62 Hypertrophy of breast	0.002	0.998	0.000
T95 Sequelae of burns, corrosions and frostbite	0.002	0.998	0.000
C16.0 Cardia	0.000	0.998	0.002
D73.8 Other diseases of spleen	0.002	0.998	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.001	0.998	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.001	0.998	0.000
E70.3 Albinism	0.001	0.998	0.000
E70.2 Disorders of tyrosine metabolism	0.001	0.998	0.000
E70.1 Other hyperphenylalaninaemias	0.001	0.998	0.000
E70.0 Classical phenylketonuria	0.001	0.998	0.000
E71.3 Disorders of fatty-acid metabolism	0.001	0.998	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.001	0.998	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.001	0.998	0.000
E71.0 Maple-syrup-urine disease	0.001	0.998	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.001	0.998	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.001	0.998	0.000
E72.5 Disorders of glycine metabolism	0.001	0.998	0.000
E72.4 Disorders of ornithine metabolism	0.001	0.998	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.001	0.998	0.000
E72.2 Disorders of urea cycle metabolism	0.001	0.998	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.001	0.998	0.000
E72.0 Disorders of amino-acid transport	0.001	0.998	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.001	0.998	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.001	0.998	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.001	0.998	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.001	0.998	0.000
E74.2 Disorders of galactose metabolism	0.001	0.998	0.000
E74.1 Disorders of fructose metabolism	0.001	0.998	0.000
E74.0 Glycogen storage disease	0.001	0.998	0.000
E75.6 Lipid storage disorder, unspecified	0.001	0.998	0.000
E75.5 Other lipid storage disorders	0.001	0.998	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.001	0.998	0.000
E75.3 Sphingolipidosis, unspecified	0.001	0.998	0.000
E75.2 Other sphingolipidosis	0.001	0.998	0.000
E75.1 Other gangliosidosis	0.001	0.998	0.000
E75.0 GM2 gangliosidosis	0.001	0.998	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.001	0.998	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.001	0.998	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.001	0.998	0.000
E76.2 Other mucopolysaccharidoses	0.001	0.998	0.000
E76.1 Mucopolysaccharidosis, type II	0.001	0.998	0.000
E76.0 Mucopolysaccharidosis, type I	0.001	0.998	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.001	0.998	0.000
E77.8 Other disorders of glycoprotein metabolism	0.001	0.998	0.000
E77.1 Defects in glycoprotein degradation	0.001	0.998	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.001	0.998	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.001	0.998	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.001	0.998	0.000
E79.1 Lesch-Nyhan syndrome	0.001	0.998	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.001	0.998	0.000
E84.9 Cystic fibrosis, unspecified	0.001	0.998	0.000
E84.8 Cystic fibrosis with other manifestations	0.001	0.998	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.001	0.998	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.001	0.998	0.000
E88.9 Metabolic disorder, unspecified	0.001	0.998	0.000
E88.8 Other specified metabolic disorders	0.001	0.998	0.000
E88.3 Tumour lysis syndrome	0.001	0.998	0.000
E88.2 Lipomatosis, not elsewhere classified	0.001	0.998	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.001	0.998	0.000
M81.4 Drug-induced osteoporosis	0.000	0.998	0.002
N60.1 Diffuse cystic mastopathy	0.002	0.998	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.002	0.998	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.002	0.998	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.001	0.998	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
D75.0 Familial erythrocytosis	0.001	0.998	0.000
N20.1 Calculus of ureter	0.000	0.998	0.002
T92.4 Sequelae of injury of nerve of upper limb	0.002	0.998	0.000
E04.8 Other specified non-toxic goitre	0.001	0.998	0.000
E04.0 Non-toxic diffuse goitre	0.001	0.998	0.000
I49.3 Ventricular premature depolarisation	0.002	0.998	0.000
D74 Methaemoglobinaemia	0.001	0.998	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.001	0.998	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.001	0.998	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.001	0.998	0.000
E55.0 Rickets, active	0.001	0.998	0.000
K92.9 Disease of digestive system, unspecified	0.002	0.998	0.000
E67 Other hyperalimentation	0.001	0.998	0.000
E68 Sequelae of hyperalimentation	0.001	0.998	0.000
C82.6 Cutaneous follicle centre lymphoma	0.001	0.998	0.000
C82.5 Diffuse follicle centre lymphoma	0.001	0.998	0.000
C82.4 Follicular lymphoma grade IIIb	0.001	0.998	0.000
C82.3 Follicular lymphoma grade IIIa	0.001	0.998	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.001	0.998	0.000
E53.8 Deficiency of other specified B group vitamins	0.002	0.998	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.998	0.002
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.000	0.998	0.001
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.000	0.998	0.001
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.000	0.998	0.001
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.000	0.998	0.001
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.001
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.000	0.998	0.001
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.000	0.998	0.001
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.000	0.998	0.001
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.000	0.998	0.001
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.000	0.998	0.001
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.001
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.000	0.998	0.001
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.001
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.001
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.001
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.000	0.998	0.001
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.001
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.001
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.001
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.001
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.001
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.000	0.998	0.001
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.001
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.001
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.001
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.000	0.998	0.001
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.001
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.001
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.001
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.001
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.001
M80.88 Other osteoporosis with pathological fracture (Other)	0.000	0.998	0.001
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.001
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.001
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.001
M80.84 Other osteoporosis with pathological fracture (Hand)	0.000	0.998	0.001
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.001
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.001
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.001
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.001
E85.8 Other amyloidosis	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations