TreeWAS
Search
Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
About
Frequently Asked Questions
Citation
Download association data
for this variant in csv format
Share this page

Variant-specific associations

rs381218
log Bayes Factor = 14.67
Chromosome 6   position 32,977,420  (GRCh37) Explore rs381218 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?
Associations at terminal nodes are shown if p(effect) ≥
Click here to show this figure without filtering.
Click on a node to zoom (except terminal nodes).
Download this figure in format
Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
E10.1 With ketoacidosis
0.966 0.034 0.000
E10.2 With renal complications
0.953 0.047 0.000
E10.4 With neurological complications
0.941 0.059 0.000
E10.0 With coma
0.864 0.136 0.000
E10.5 With peripheral circulatory complications
0.860 0.140 0.000
E10-E14 Diabetes mellitus
0.857 0.143 0.000
E10.6 With other specified complications
0.856 0.144 0.000
E10.8 With unspecified complications
0.851 0.149 0.000
E10.7 With multiple complications
0.824 0.176 0.000
E11 Non-insulin-dependent diabetes mellitus
0.779 0.221 0.000
E11.2 With renal complications
0.760 0.240 0.000
E13 Other specified diabetes mellitus
0.709 0.291 0.000
E14 Unspecified diabetes mellitus
0.689 0.311 0.000
E11.5 With peripheral circulatory complications
0.670 0.330 0.000
E14.3 With ophthalmic complications
0.638 0.362 0.000
E12 Malnutrition-related diabetes mellitus
0.615 0.385 0.000
E11.6 With other specified complications
0.600 0.400 0.000
E11.1 With ketoacidosis
0.594 0.406 0.000
E11.3 With ophthalmic complications
0.570 0.430 0.000
E13.9 Without complications
0.568 0.432 0.000
E13.3 With ophthalmic complications
0.558 0.441 0.000
E11.7 With multiple complications
0.558 0.442 0.000
E14.6 With other specified complications
0.545 0.455 0.000
E14.2 Withrenal complications
0.522 0.478 0.000
E14.8 With unspecified complications
0.516 0.484 0.000
E13.8 With unspecified complications
0.509 0.491 0.000
E13.7 With multiple complications
0.509 0.491 0.000
E13.6 With other specified complications
0.509 0.491 0.000
E13.5 With peripheral circulatory complications
0.509 0.491 0.000
E13.4 With neurological complications
0.509 0.491 0.000
E13.2 With renal complications
0.509 0.491 0.000
E13.1 With ketoacidosis
0.509 0.491 0.000
E13.0 With coma
0.509 0.491 0.000
E11.8 With unspecified complications
0.508 0.492 0.000
E14.7 With multiple complications
0.494 0.506 0.000
E14.5 With peripheral circulatory complications
0.494 0.506 0.000
E14.0 With coma
0.494 0.506 0.000
E11.0 With coma
0.483 0.517 0.000
E14.1 With ketoacidosis
0.458 0.542 0.000
E12.9 Without complications
0.441 0.559 0.000
E12.8 With unspecified complications
0.441 0.559 0.000
E12.7 With multiple complications
0.441 0.559 0.000
E12.6 With other specified complications
0.441 0.559 0.000
E12.5 With peripheral circulatory complications
0.441 0.559 0.000
E12.4 With neurological complications
0.441 0.559 0.000
E12.3 With ophthalmic complications
0.441 0.559 0.000
E12.2 With renal complications
0.441 0.559 0.000
E12.1 With ketoacidosis
0.441 0.559 0.000
E12.0 With coma
0.441 0.559 0.000
E11.4 With neurological complications
0.393 0.607 0.000
E14.4 With neurological complications
0.378 0.622 0.000
E14.9 Without complications
0.260 0.740 0.000
E16.2 Hypoglycaemia, unspecified
0.123 0.877 0.000
E16 Other disorders of pancreatic internal secretion
0.119 0.881 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.116 0.884 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.114 0.886 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.101 0.899 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.085 0.915 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.085 0.915 0.000
E16.4 Abnormal secretion of gastrin
0.085 0.915 0.000
E16.3 Increased secretion of glucagon
0.085 0.915 0.000
E15 Nondiabetic hypoglycaemic coma
0.083 0.917 0.000
E11.9 Without complications
0.083 0.917 0.000
E40-E46 Malnutrition
0.081 0.919 0.000
E50-E64 Other nutritional deficiencies
0.065 0.935 0.000
E16.1 Other hypoglycaemia
0.059 0.941 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.058 0.942 0.000
E45 Retarded development following protein-energy malnutrition
0.058 0.942 0.000
E43 Unspecified severe protein-energy malnutrition
0.058 0.942 0.000
E42 Marasmic kwashiorkor
0.058 0.942 0.000
E41 Nutritional marasmus
0.058 0.942 0.000
E40 Kwashiorkor
0.058 0.942 0.000
E46 Unspecified protein-energy malnutrition
0.056 0.943 0.000
E53 Deficiency of other B group vitamins
0.053 0.947 0.000
E54 Ascorbic acid deficiency
0.049 0.951 0.000
E65-E68 Obesity and other hyperalimentation
0.048 0.951 0.000
E53.8 Deficiency of other specified B group vitamins
0.048 0.952 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.047 0.953 0.000
E63 Other nutritional deficiencies
0.047 0.953 0.000
E56 Other vitamin deficiencies
0.047 0.953 0.000
E50 Vitamin A deficiency
0.047 0.953 0.000
E60 Dietary zinc deficiency
0.047 0.953 0.000
E59 Dietary selenium deficiency
0.047 0.953 0.000
E58 Dietary calcium deficiency
0.047 0.953 0.000
E52 Niacin deficiency [pellagra]
0.047 0.953 0.000
E51 Thiamine deficiency
0.046 0.954 0.000
E44.1 Mild protein-energy malnutrition
0.042 0.958 0.000
E44.0 Moderate protein-energy malnutrition
0.042 0.958 0.000
E00-E07 Disorders of thyroid gland
0.039 0.961 0.000
E53.1 Pyridoxine deficiency
0.038 0.962 0.000
E53.0 Riboflavin deficiency
0.038 0.962 0.000
E67 Other hyperalimentation
0.035 0.965 0.000
E68 Sequelae of hyperalimentation
0.035 0.965 0.000
E61 Deficiency of other nutrient elements
0.034 0.966 0.000
E50.9 Vitamin A deficiency, unspecified
0.033 0.966 0.000
E50.8 Other manifestations of vitamin A deficiency
0.033 0.966 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.033 0.966 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.033 0.966 0.000
E50.5 Vitamin A deficiency with night blindness
0.033 0.966 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.033 0.966 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.033 0.966 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.033 0.966 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.033 0.966 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.033 0.966 0.000
E56.9 Vitamin deficiency, unspecified
0.033 0.966 0.000
E56.8 Deficiency of other vitamins
0.033 0.966 0.000
E56.1 Deficiency of vitamin K
0.033 0.966 0.000
E56.0 Deficiency of vitamin E
0.033 0.966 0.000
E63.9 Nutritional deficiency, unspecified
0.033 0.966 0.000
E63.8 Other specified nutritional deficiencies
0.033 0.966 0.000
E63.1 Imbalance of constituents of food intake
0.033 0.966 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.033 0.966 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.033 0.966 0.000
E64.8 Sequelae of other nutritional deficiencies
0.033 0.966 0.000
E64.3 Sequelae of rickets
0.033 0.966 0.000
E64.2 Sequelae of vitamin C deficiency
0.033 0.966 0.000
E64.1 Sequelae of vitamin A deficiency
0.033 0.966 0.000
E64.0 Sequelae of protein-energy malnutrition
0.033 0.966 0.000
E65 Localised adiposity
0.033 0.966 0.000
E51.9 Thiamine deficiency, unspecified
0.033 0.967 0.000
E51.8 Other manifestations of thiamine deficiency
0.033 0.967 0.000
E51.1 Beriberi
0.033 0.967 0.000
E51.2 Wernicke's encephalopathy
0.032 0.968 0.000
E04 Other non-toxic goitre
0.032 0.968 0.000
E04.2 Non-toxic multinodular goitre
0.031 0.969 0.000
E53.9 Vitamin B deficiency, unspecified
0.031 0.969 0.000
E55 Vitamin D deficiency
0.030 0.970 0.000
T42.4 Benzodiazepines
0.000 0.970 0.030
E02 Subclinical iodine-deficiency hypothyroidism
0.030 0.970 0.000
E06 Thyroiditis
0.029 0.971 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.028 0.972 0.000
E00 Congenital iodine-deficiency syndrome
0.028 0.972 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.973 0.027
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.974 0.026
E67.8 Other specified hyperalimentation
0.025 0.975 0.000
E67.3 Hypervitaminosis D
0.025 0.975 0.000
E67.2 Megavitamin-B6 syndrome
0.025 0.975 0.000
E67.1 Hypercarotenaemia
0.025 0.975 0.000
E67.0 Hypervitaminosis A
0.025 0.975 0.000
E07 Other disorders of thyroid
0.025 0.975 0.000
E61.2 Magnesium deficiency
0.024 0.975 0.000
E06.9 Thyroiditis, unspecified
0.025 0.975 0.000
E61.9 Deficiency of nutrient element, unspecified
0.024 0.975 0.000
E61.8 Deficiency of other specified nutrient elements
0.024 0.975 0.000
E61.7 Deficiency of multiple nutrient elements
0.024 0.975 0.000
E61.6 Vanadium deficiency
0.024 0.975 0.000
E61.5 Molybdenum deficiency
0.024 0.975 0.000
E61.4 Chromium deficiency
0.024 0.975 0.000
E61.3 Manganese deficiency
0.024 0.975 0.000
E61.0 Copper deficiency
0.024 0.975 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.976 0.024
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.976 0.024
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.976 0.024
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.000 0.976 0.023
E04.8 Other specified non-toxic goitre
0.023 0.977 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.977 0.023
T39.1 4-Aminophenol derivatives
0.000 0.978 0.022
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.000 0.978 0.022
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.978 0.022
E55.0 Rickets, active
0.022 0.978 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.000 0.978 0.022
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.979 0.021
T36 Poisoning by systemic antibiotics
0.000 0.979 0.021
T40.4 Other synthetic narcotics
0.000 0.979 0.021
K90.0 Coeliac disease
0.000 0.979 0.021
E06.4 Drug-induced thyroiditis
0.021 0.979 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.021 0.979 0.000
E06.1 Subacute thyroiditis
0.021 0.979 0.000
E06.0 Acute thyroiditis
0.021 0.979 0.000
E06.5 Other chronic thyroiditis
0.021 0.979 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.979 0.021
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.020 0.980 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.020 0.980 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.020 0.980 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.020 0.980 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.020 0.980 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.020 0.980 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.020 0.980 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.020 0.980 0.000
E04.1 Non-toxic single thyroid nodule
0.020 0.980 0.000
E07.9 Disorder of thyroid, unspecified
0.020 0.980 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.980 0.020
T42.2 Succinimides and oxazolidinediones
0.000 0.980 0.020
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.000 0.980 0.020
E04.0 Non-toxic diffuse goitre
0.020 0.980 0.000
T42.0 Hydantoin derivatives
0.000 0.980 0.020
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.981 0.019
T42.1 Iminostilbenes
0.000 0.981 0.019
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.981 0.019
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.981 0.019
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.981 0.019
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.981 0.019
T47.1 Other antacids and anti-gastric-secretion drugs
0.000 0.981 0.019
T40.6 Other and unspecified narcotics
0.000 0.981 0.019
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.981 0.019
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.982 0.018
E07.1 Dyshormogenetic goitre
0.018 0.982 0.000
E07.0 Hypersecretion of calcitonin
0.018 0.982 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.982 0.018
T36.0 Penicillins
0.000 0.982 0.018
T46.1 Calcium-channel blockers
0.000 0.982 0.018
T50.7 Analeptics and opioid receptor antagonists
0.000 0.982 0.018
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.982 0.018
T50.5 Appetite depressants
0.000 0.982 0.018
T50.4 Drugs affecting uric acid metabolism
0.000 0.982 0.018
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.982 0.018
T50.1 Loop [high-ceiling] diuretics
0.000 0.982 0.018
T50.0 Mineralocorticoids and their antagonists
0.000 0.982 0.018
T39.4 Antirheumatics, not elsewhere classified
0.000 0.982 0.018
T39.2 Pyrazolone derivatives
0.000 0.982 0.018
T42.3 Barbiturates
0.000 0.982 0.017
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.000 0.983 0.017
T40.8 Lysergide [LSD]
0.000 0.983 0.017
T40.7 Cannabis (derivatives)
0.000 0.983 0.017
T40.3 Methadone
0.000 0.983 0.017
T40.1 Heroin
0.000 0.983 0.017
T40.0 Opium
0.000 0.983 0.017
T40.5 Cocaine
0.000 0.983 0.017
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.983 0.017
T38.9 Other and unspecified hormone antagonists
0.000 0.983 0.017
T38.8 Other and unspecified hormones and their synthetic substitutes
0.000 0.983 0.017
T38.7 Androgens and anabolic congeners
0.000 0.983 0.017
T38.5 Other oestrogens and progestogens
0.000 0.983 0.017
T38.4 Oral contraceptives
0.000 0.983 0.017
T38.2 Antithyroid drugs
0.000 0.983 0.017
T38.0 Glucocorticoids and synthetic analogues
0.000 0.983 0.017
E06.3 Autoimmune thyroiditis
0.016 0.983 0.000
T40.2 Other opioids
0.000 0.984 0.016
E04.9 Non-toxic goitre, unspecified
0.016 0.984 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.000 0.984 0.016
T46.8 Antivaricose drugs, including sclerosing agents
0.000 0.984 0.016
T46.7 Peripheral vasodilators
0.000 0.984 0.016
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.000 0.984 0.016
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.000 0.984 0.016
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.000 0.984 0.015
T47.8 Other agents primarily affecting the gastro-intestinal system
0.000 0.984 0.015
T47.7 Emetics
0.000 0.984 0.015
T47.6 Antidiarrhoeal drugs
0.000 0.984 0.015
T47.5 Digestants
0.000 0.984 0.015
T47.4 Other laxatives
0.000 0.984 0.015
T47.3 Saline and osmotic laxatives
0.000 0.984 0.015
T47.2 Stimulant laxatives
0.000 0.984 0.015
T36.9 Systemic antibiotic, unspecified
0.000 0.984 0.015
T36.8 Other systemic antibiotics
0.000 0.984 0.015
T36.7 Antifungal antibiotics, systemically used
0.000 0.984 0.015
T36.6 Rifamycins
0.000 0.984 0.015
T36.5 Aminoglycosides
0.000 0.984 0.015
T36.4 Tetracyclines
0.000 0.984 0.015
T36.2 Chloramphenicol group
0.000 0.984 0.015
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.000 0.984 0.015
T46.3 Coronary vasodilators, not elsewhere classified
0.000 0.985 0.015
O70.0 First degree perineal laceration during delivery
0.015 0.985 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.000 0.985 0.015
T36.3 Macrolides
0.000 0.985 0.015
T50.8 Diagnostic agents
0.000 0.985 0.014
T37.8 Other specified systemic anti-infectives and antiparasitics
0.000 0.986 0.014
K22.9 Disease of oesophagus, unspecified
0.014 0.986 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.000 0.986 0.014
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.000 0.986 0.014
T37.5 Antiviral drugs
0.000 0.986 0.014
T37.4 Anthelminthics
0.000 0.986 0.014
T37.3 Other antiprotozoal drugs
0.000 0.986 0.014
T37.2 Antimalarials and drugs acting on other blood protozoa
0.000 0.986 0.014
T37.1 Antimycobacterial drugs
0.000 0.986 0.014
T37.0 Sulphonamides
0.000 0.986 0.014
T41.5 Therapeutic gases
0.000 0.986 0.014
T41.4 Anaesthetic, unspecified
0.000 0.986 0.014
T41.3 Local anaesthetics
0.000 0.986 0.014
T41.2 Other and unspecified general anaesthetics
0.000 0.986 0.014
T41.1 Intravenous anaesthetics
0.000 0.986 0.014
T41.0 Inhaled anaesthetics
0.000 0.986 0.014
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.000 0.986 0.014
T48.6 Antiasthmatics, not elsewhere classified
0.000 0.986 0.014
T48.5 Anti-common-cold drugs
0.000 0.986 0.014
T48.4 Expectorants
0.000 0.986 0.014
T48.3 Antitussives
0.000 0.986 0.014
T48.2 Other and unspecified agents primarily acting on muscles
0.000 0.986 0.014
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.000 0.986 0.014
T48.0 Oxytocic drugs
0.000 0.986 0.014
T49.9 Topical agent, unspecified
0.000 0.986 0.014
T49.8 Other topical agents
0.000 0.986 0.014
T49.7 Dental drugs, topically applied
0.000 0.986 0.014
T49.6 Otorhinolaryngological drugs and preparations
0.000 0.986 0.014
T49.5 Ophthalmological drugs and preparations
0.000 0.986 0.014
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.000 0.986 0.014
T49.3 Emollients, demulcents and protectants
0.000 0.986 0.014
T49.2 Local astringents and local detergents
0.000 0.986 0.014
T49.1 Antipruritics
0.000 0.986 0.014
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.000 0.986 0.014
T47.0 Histamine H(2)-receptor antagonists
0.000 0.986 0.014
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.986 0.014
T38.1 Thyroid hormones and substitutes
0.000 0.986 0.013
T46.4 Angiotensin-converting-enzyme inhibitors
0.000 0.987 0.013
D41.0 Kidney
0.013 0.987 0.000
K60.3 Anal fistula
0.000 0.988 0.012
E03 Other hypothyroidism
0.012 0.988 0.000
E07.8 Other specified disorders of thyroid
0.011 0.988 0.000
E20-E35 Disorders of other endocrine glands
0.012 0.988 0.000
T39.0 Salicylates
0.000 0.988 0.012
N08.3 Glomerular disorders in diabetes mellitus
0.012 0.988 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.988 0.012
E61.1 Iron deficiency
0.011 0.988 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.002 0.989 0.010
E26 Hyperaldosteronism
0.011 0.989 0.000
T45.0 Antiallergic and antiemetic drugs
0.000 0.989 0.011
J33.0 Polyp of nasal cavity
0.011 0.989 0.000
D37.7 Other digestive organs
0.011 0.989 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.000 0.990 0.010
T45.8 Other primarily systemic and haematological agents
0.000 0.990 0.010
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.000 0.990 0.010
T45.6 Fibrinolysis-affecting drugs
0.000 0.990 0.010
T45.4 Iron and its compounds
0.000 0.990 0.010
T45.3 Enzymes, not elsewhere classified
0.000 0.990 0.010
E26.0 Primary hyperaldosteronism
0.010 0.990 0.000
E29 Testicular dysfunction
0.010 0.990 0.000
H66.9 Otitis media, unspecified
0.000 0.990 0.010
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.010 0.990 0.000
D37.6 Liver, gallbladder and bile ducts
0.010 0.990 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.010 0.990 0.000
E25 Adrenogenital disorders
0.009 0.991 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.000 0.991 0.009
E26.9 Hyperaldosteronism, unspecified
0.009 0.991 0.000
E31 Polyglandular dysfunction
0.009 0.991 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.000 0.991 0.009
D37.1 Stomach
0.009 0.991 0.000
E03.5 Myxoedema coma
0.009 0.991 0.000
E03.4 Atrophy of thyroid (acquired)
0.009 0.991 0.000
E03.3 Postinfectious hypothyroidism
0.009 0.991 0.000
E03.1 Congenital hypothyroidism without goitre
0.009 0.991 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.009 0.991 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.000 0.991 0.009
E03.8 Other specified hypothyroidism
0.009 0.991 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.009 0.991 0.000
E32 Diseases of thymus
0.009 0.991 0.000
E30 Disorders of puberty, not elsewhere classified
0.009 0.991 0.000
T43.9 Psychotropic drug, unspecified
0.000 0.991 0.008
T43.8 Other psychotropic drugs, not elsewhere classified
0.000 0.991 0.008
T43.6 Psychostimulants with abuse potential
0.000 0.991 0.008
T45.2 Vitamins, not elsewhere classified
0.000 0.991 0.008
D39.1 Ovary
0.008 0.992 0.000
E20 Hypoparathyroidism
0.008 0.992 0.000
D37.5 Rectum
0.008 0.992 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.000 0.992 0.008
E29.1 Testicular hypofunction
0.008 0.992 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.008 0.992 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.001 0.992 0.007
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.001 0.992 0.007
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.001 0.992 0.007
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.001 0.992 0.007
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.001 0.992 0.007
T44.1 Other parasympathomimetics [cholinergics]
0.001 0.992 0.007
T44.0 Anticholinesterase agents
0.001 0.992 0.007
D41.2 Ureter
0.008 0.992 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.000 0.992 0.008
E26.8 Other hyperaldosteronism
0.008 0.992 0.000
E26.1 Secondary hyperaldosteronism
0.008 0.992 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.008 0.992 0.000
T51.0 Ethanol
0.000 0.992 0.008
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.001 0.992 0.007
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.008 0.992 0.000
D37.3 Appendix
0.008 0.992 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.007 0.993 0.000
T45.5 Anticoagulants
0.000 0.993 0.007
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.001 0.993 0.006
E29.9 Testicular dysfunction, unspecified
0.007 0.993 0.000
E29.8 Other testicular dysfunction
0.007 0.993 0.000
E29.0 Testicular hyperfunction
0.007 0.993 0.000
E31.0 Autoimmune polyglandular failure
0.007 0.993 0.000
D41.9 Urinary organ, unspecified
0.007 0.993 0.000
D41.7 Other urinary organs
0.007 0.993 0.000
D41.3 Urethra
0.007 0.993 0.000
D41.1 Renal pelvis
0.007 0.993 0.000
I08.0 Disorders of both mitral and aortic valves
0.000 0.993 0.007
K12.2 Cellulitis and abscess of mouth
0.000 0.993 0.007
K90 Intestinal malabsorption
0.000 0.993 0.007
E25.9 Adrenogenital disorder, unspecified
0.007 0.993 0.000
E25.8 Other adrenogenital disorders
0.007 0.993 0.000
S67.0 Crushing injury of thumb and other finger(s)
0.007 0.993 0.000
D39.7 Other female genital organs
0.007 0.993 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.007 0.993 0.000
E31.9 Polyglandular dysfunction, unspecified
0.007 0.993 0.000
E31.8 Other polyglandular dysfunction
0.007 0.993 0.000
E31.1 Polyglandular hyperfunction
0.007 0.993 0.000
E34 Other endocrine disorders
0.006 0.993 0.000
E30.9 Disorder of puberty, unspecified
0.006 0.993 0.000
E30.8 Other disorders of puberty
0.006 0.993 0.000
E30.1 Precocious puberty
0.006 0.993 0.000
E30.0 Delayed puberty
0.006 0.993 0.000
E32.9 Disease of thymus, unspecified
0.006 0.993 0.000
E32.8 Other diseases of thymus
0.006 0.993 0.000
E32.1 Abscess of thymus
0.006 0.993 0.000
E32.0 Persistent hyperplasia of thymus
0.006 0.993 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.006 0.993 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.006 0.993 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.006 0.993 0.000
D44.1 Adrenal gland
0.006 0.993 0.000
D44.4 Craniopharyngeal duct
0.006 0.994 0.000
T43.2 Other and unspecified antidepressants
0.000 0.994 0.006
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.006 0.994 0.000
E20.8 Other hypoparathyroidism
0.006 0.994 0.000
E20.1 Pseudohypoparathyroidism
0.006 0.994 0.000
E20.0 Idiopathic hypoparathyroidism
0.006 0.994 0.000
E22 Hyperfunction of pituitary gland
0.006 0.994 0.000
D39.9 Female genital organ, unspecified
0.006 0.994 0.000
D39.2 Placenta
0.006 0.994 0.000
D44.6 Carotid body
0.006 0.994 0.000
D39.0 Uterus
0.006 0.994 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.006 0.994 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.006 0.994 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.006 0.994 0.000
E20.9 Hypoparathyroidism, unspecified
0.006 0.994 0.000
D44.0 Thyroid gland
0.006 0.994 0.000
E66 Obesity
0.005 0.994 0.000
E21.4 Other specified disorders of parathyroid gland
0.006 0.994 0.000
E55.9 Vitamin D deficiency, unspecified
0.005 0.994 0.001
D44.7 Aortic body and other paraganglia
0.006 0.994 0.000
D37.9 Digestive organ, unspecified
0.006 0.994 0.000
D44.9 Endocrine gland, unspecified
0.005 0.994 0.000
D44.5 Pineal gland
0.005 0.994 0.000
D44.2 Parathyroid gland
0.005 0.994 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.000 0.994 0.005
E28 Ovarian dysfunction
0.005 0.994 0.000
K90.8 Other intestinal malabsorption
0.000 0.994 0.005
E34.0 Carcinoid syndrome
0.005 0.995 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.005 0.995 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.995 0.005
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.995 0.005
K90.1 Tropical sprue
0.000 0.995 0.005
M54.39 Sciatica (Site unspecified)
0.000 0.995 0.005
D44.3 Pituitary gland
0.005 0.995 0.000
D37.2 Small intestine
0.005 0.995 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.005 0.995 0.000
E34.5 Androgen resistance syndrome
0.005 0.995 0.000
E34.4 Constitutional tall stature
0.005 0.995 0.000
E34.3 Short stature, not elsewhere classified
0.005 0.995 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.005 0.995 0.000
E34.1 Other hypersecretion of intestinal hormones
0.005 0.995 0.000
E22.1 Hyperprolactinaemia
0.005 0.995 0.000
D38.5 Other respiratory organs
0.005 0.995 0.000
H17.9 Corneal scar and opacity, unspecified
0.005 0.995 0.000
D45 Polycythaemia vera
0.005 0.995 0.000
E24 Cushing's syndrome
0.005 0.995 0.000
D40.1 Testis
0.005 0.995 0.000
Z50.0 Cardiac rehabilitation
0.000 0.995 0.005
E34.8 Other specified endocrine disorders
0.004 0.995 0.000
K01.1 Impacted teeth
0.000 0.995 0.005
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.003 0.995 0.002
E21.2 Other hyperparathyroidism
0.005 0.995 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.005 0.995 0.000
E22.8 Other hyperfunction of pituitary gland
0.005 0.995 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.995 0.005
K65.9 Peritonitis, unspecified
0.000 0.995 0.005
D38.6 Respiratory organ, unspecified
0.004 0.995 0.000
D38.4 Thymus
0.004 0.995 0.000
D38.3 Mediastinum
0.004 0.995 0.000
D38.2 Pleura
0.004 0.995 0.000
D40.9 Male genital organ, unspecified
0.004 0.995 0.000
D40.7 Other male genital organs
0.004 0.995 0.000
D42.9 Meninges, unspecified
0.004 0.995 0.000
D42.1 Spinal meninges
0.004 0.995 0.000
D42.0 Cerebral meninges
0.004 0.995 0.000
M54.36 Sciatica (Lumbar region)
0.000 0.995 0.005
D44.8 Pluriglandular involvement
0.004 0.995 0.000
M54.3 Sciatica
0.000 0.995 0.005
K90.9 Intestinal malabsorption, unspecified
0.000 0.995 0.004
E21.5 Disorder of parathyroid gland, unspecified
0.004 0.996 0.000
D41.4 Bladder
0.004 0.996 0.000
E66.1 Drug-induced obesity
0.004 0.996 0.000
S92.30 Fracture of metatarsal bone (closed)
0.000 0.996 0.004
D38.1 Trachea, bronchus and lung
0.004 0.996 0.000
D43.0 Brain, supratentorial
0.004 0.996 0.000
E66.0 Obesity due to excess calories
0.004 0.996 0.000
E23 Hypofunction and other disorders of pituitary gland
0.004 0.996 0.000
D38.0 Larynx
0.004 0.996 0.000
E28.9 Ovarian dysfunction, unspecified
0.004 0.996 0.000
E28.8 Other ovarian dysfunction
0.004 0.996 0.000
E28.1 Androgen excess
0.004 0.996 0.000
E28.0 Oestrogen excess
0.004 0.996 0.000
D46 Myelodysplastic syndromes
0.004 0.996 0.000
D40.0 Prostate
0.004 0.996 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.000 0.996 0.004
D43.1 Brain, infratentorial
0.004 0.996 0.000
E22.0 Acromegaly and pituitary gigantism
0.004 0.996 0.000
D43.9 Central nervous system, unspecified
0.004 0.996 0.000
D43.7 Other parts of central nervous system
0.004 0.996 0.000
D43.3 Cranial nerves
0.004 0.996 0.000
F20.9 Schizophrenia, unspecified
0.004 0.996 0.000
C67.5 Bladder neck
0.000 0.996 0.004
D43.4 Spinal cord
0.004 0.996 0.000
E24.8 Other Cushing's syndrome
0.003 0.996 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.003 0.996 0.000
E24.3 Ectopic ACTH syndrome
0.003 0.996 0.000
E24.1 Nelson's syndrome
0.003 0.996 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.004 0.996 0.000
E28.3 Primary ovarian failure
0.003 0.996 0.000
M54.37 Sciatica (Lumbosacral region)
0.000 0.996 0.004
N05.9 Unspecified
0.000 0.996 0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

TreeWAS Database © 2019 - 2024 About Frequently Asked Questions Citation Contact Terms & Conditions This website does not use cookies to collect any personal information about you.