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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3813570
log Bayes Factor = 18.5201
Chromosome 15   position 78,832,832  (GRCh37) Explore rs3813570 on Ensembl!
Variant rs3813570 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.000 1.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.000 1.000
J43.9 Emphysema, unspecified
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
I71 Aortic aneurysm and dissection
0.000 0.000 1.000
J43 Emphysema
0.000 0.000 1.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.000 1.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.001 0.999
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.004 0.996
Chapter X Diseases of the respiratory system
0.000 0.006 0.994
I73 Other peripheral vascular diseases
0.000 0.007 0.993
I70 Atherosclerosis
0.000 0.008 0.992
J90-J94 Other diseases of pleura
0.000 0.008 0.992
J92 Pleural plaque
0.000 0.012 0.988
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.012 0.988
I73.9 Peripheral vascular disease, unspecified
0.000 0.017 0.983
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.017 0.983
J42 Unspecified chronic bronchitis
0.000 0.022 0.978
I60-I69 Cerebrovascular diseases
0.000 0.027 0.973
Chapter IX Diseases of the circulatory system
0.000 0.029 0.971
J92.0 Pleural plaque with presence of asbestos
0.000 0.030 0.970
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.035 0.965
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.036 0.964
I60 Subarachnoid haemorrhage
0.000 0.043 0.957
J95-J99 Other diseases of the respiratory system
0.000 0.043 0.957
J60-J70 Lung diseases due to external agents
0.000 0.043 0.957
I67 Other cerebrovascular diseases
0.000 0.056 0.944
J92.9 Pleural plaque without asbestos
0.000 0.060 0.940
J90 Pleural effusion, not elsewhere classified
0.000 0.065 0.935
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.065 0.935
J98 Other respiratory disorders
0.000 0.067 0.933
I69 Sequelae of cerebrovascular disease
0.000 0.068 0.932
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.068 0.932
I26 Pulmonary embolism
0.000 0.073 0.927
I27 Other pulmonary heart diseases
0.000 0.075 0.925
J98.1 Pulmonary collapse
0.000 0.080 0.920
I77 Other disorders of arteries and arterioles
0.000 0.086 0.914
I27.9 Pulmonary heart disease, unspecified
0.000 0.090 0.910
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.090 0.910
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.093 0.907
I67.9 Cerebrovascular disease, unspecified
0.000 0.104 0.896
I72 Other aneurysm
0.000 0.119 0.881
I73.0 Raynaud's syndrome
0.000 0.119 0.881
I69.3 Sequelae of cerebral infarction
0.000 0.122 0.878
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.127 0.873
J86 Pyothorax
0.000 0.139 0.861
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.149 0.851
I60.8 Other subarachnoid haemorrhage
0.000 0.158 0.842
J93 Pneumothorax
0.000 0.164 0.836
J43.2 Centrilobular emphysema
0.000 0.166 0.834
J98.4 Other disorders of lung
0.000 0.170 0.830
J86.9 Pyothorax without fistula
0.000 0.170 0.830
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.171 0.829
I67.1 Cerebral aneurysm, nonruptured
0.000 0.174 0.826
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.174 0.826
I67.8 Other specified cerebrovascular diseases
0.000 0.176 0.824
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.179 0.821
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.185 0.815
I77.1 Stricture of artery
0.000 0.186 0.814
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.195 0.805
I72.0 Aneurysm of carotid artery
0.000 0.196 0.804
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.200 0.800
I71.0 Dissection of aorta [any part]
0.000 0.210 0.790
I77.0 Arteriovenous fistula, acquired
0.000 0.211 0.789
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.219 0.781
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.225 0.775
J93.1 Other spontaneous pneumothorax
0.000 0.227 0.773
I70.0 Atherosclerosis of aorta
0.000 0.230 0.770
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.233 0.767
J98.9 Respiratory disorder, unspecified
0.000 0.242 0.758
J60 Coalworker's pneumoconiosis
0.000 0.243 0.757
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.253 0.747
I72.8 Aneurysm of other specified arteries
0.000 0.262 0.738
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.263 0.737
I78 Diseases of capillaries
0.000 0.281 0.719
J41 Simple and mucopurulent chronic bronchitis
0.000 0.283 0.717
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.283 0.717
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.283 0.717
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.283 0.717
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.283 0.717
J43.1 Panlobular emphysema
0.000 0.283 0.717
J43.0 MacLeod's syndrome
0.000 0.283 0.717
I77.2 Rupture of artery
0.000 0.284 0.716
J64 Unspecified pneumoconiosis
0.000 0.285 0.715
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.288 0.712
I70.9 Generalised and unspecified atherosclerosis
0.000 0.288 0.711
I70.8 Atherosclerosis of other arteries
0.000 0.288 0.711
I28 Other diseases of pulmonary vessels
0.000 0.297 0.703
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.299 0.701
I61 Intracerebral haemorrhage
0.000 0.305 0.695
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.306 0.694
I00-I02 Acute rheumatic fever
0.000 0.306 0.693
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.314 0.686
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.314 0.686
J96 Respiratory failure, not elsewhere classified
0.000 0.314 0.686
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.314 0.686
J66 Airway disease due to specific organic dust
0.000 0.314 0.686
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.314 0.686
J62 Pneumoconiosis due to dust containing silica
0.000 0.314 0.686
J65 Pneumoconiosis associated with tuberculosis
0.000 0.314 0.686
I27.8 Other specified pulmonary heart diseases
0.000 0.316 0.684
J98.2 Interstitial emphysema
0.000 0.317 0.683
I72.9 Aneurysm of unspecified site
0.000 0.323 0.677
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.323 0.677
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.323 0.677
I67.5 Moyamoya disease
0.000 0.323 0.677
I67.4 Hypertensive encephalopathy
0.000 0.323 0.677
I67.3 Progressive vascular leukoencephalopathy
0.000 0.323 0.677
J69 Pneumonitis due to solids and liquids
0.000 0.328 0.672
J98.3 Compensatory emphysema
0.000 0.331 0.669
I27.1 Kyphoscoliotic heart disease
0.000 0.336 0.663
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.337 0.663
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.341 0.659
I77.5 Necrosis of artery
0.000 0.345 0.655
I77.4 Coeliac artery compression syndrome
0.000 0.345 0.655
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.349 0.651
I74 Arterial embolism and thrombosis
0.000 0.355 0.645
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.356 0.643
J70 Respiratory conditions due to other external agents
0.000 0.367 0.633
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.368 0.632
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.368 0.632
I72.1 Aneurysm of artery of upper extremity
0.000 0.368 0.632
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.371 0.629
I27.0 Primary pulmonary hypertension
0.000 0.374 0.626
I73.8 Other specified peripheral vascular diseases
0.000 0.374 0.626
J93.0 Spontaneous tension pneumothorax
0.000 0.377 0.623
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.379 0.621
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.383 0.617
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.384 0.616
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.384 0.616
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.384 0.616
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.384 0.615
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.389 0.611
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.391 0.609
I70.1 Atherosclerosis of renal artery
0.000 0.406 0.594
J85 Abscess of lung and mediastinum
0.000 0.407 0.593
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.408 0.592
I79.1 Aortitis in diseases classified elsewhere
0.000 0.408 0.592
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.408 0.592
J98.6 Disorders of diaphragm
0.000 0.409 0.591
J86.0 Pyothorax with fistula
0.000 0.412 0.588
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.418 0.582
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.420 0.579
J43.8 Other emphysema
0.000 0.422 0.578
J99.0 Rheumatoid lung disease
0.000 0.424 0.576
I72.3 Aneurysm of iliac artery
0.000 0.426 0.574
I68.0 Cerebral amyloid angiopathy
0.000 0.432 0.568
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.448 0.552
J93.8 Other pneumothorax
0.000 0.451 0.549
I72.2 Aneurysm of renal artery
0.000 0.459 0.541
I77.3 Arterial fibromuscular dysplasia
0.000 0.460 0.540
J40 Bronchitis, not specified as acute or chronic
0.000 0.464 0.536
I72.4 Aneurysm of artery of lower extremity
0.000 0.465 0.535
J94 Other pleural conditions
0.000 0.471 0.529
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.471 0.528
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.471 0.528
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.471 0.528
I77.8 Other specified disorders of arteries and arterioles
0.000 0.473 0.527
I77.6 Arteritis, unspecified
0.000 0.479 0.521
J69.8 Pneumonitis due to other solids and liquids
0.000 0.480 0.520
I67.2 Cerebral atherosclerosis
0.000 0.482 0.518
I28.8 Other specified diseases of pulmonary vessels
0.000 0.484 0.516
I78.9 Disease of capillaries, unspecified
0.000 0.485 0.515
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.1 Mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.0 Simple chronic bronchitis
0.000 0.486 0.514
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.489 0.511
I62 Other nontraumatic intracranial haemorrhage
0.000 0.489 0.511
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.490 0.510
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.490 0.510
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.490 0.510
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.490 0.510
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.496 0.504
I28.1 Aneurysm of pulmonary artery
0.000 0.496 0.504
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.496 0.504
I02 Rheumatic chorea
0.000 0.503 0.497
I01 Rheumatic fever with heart involvement
0.000 0.503 0.497
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.503 0.497
I78.8 Other diseases of capillaries
0.000 0.504 0.496
I00 Rheumatic fever without mention of heart involvement
0.000 0.505 0.495
J96.9 Respiratory failure, unspecified
0.000 0.508 0.492
J96.1 Chronic respiratory failure
0.000 0.508 0.492
J96.0 Acute respiratory failure
0.000 0.508 0.492
J62.8 Pneumoconiosis due to other dust containing silica
0.000 0.508 0.492
J62.0 Pneumoconiosis due to talc dust
0.000 0.508 0.492
J63.8 Pneumoconiosis due to other specified inorganic dusts
0.000 0.508 0.492
J63.5 Stannosis
0.000 0.508 0.492
J63.4 Siderosis
0.000 0.508 0.492
J63.3 Graphite fibrosis (of lung)
0.000 0.508 0.492
J63.2 Berylliosis
0.000 0.508 0.492
J63.1 Bauxite fibrosis (of lung)
0.000 0.508 0.492
J63.0 Aluminosis (of lung)
0.000 0.508 0.492
J66.8 Airway disease due to other specific organic dusts
0.000 0.508 0.492
J66.2 Cannabinosis
0.000 0.508 0.492
J66.1 Flax-dresser's disease
0.000 0.508 0.492
J66.0 Byssinosis
0.000 0.508 0.492
J68.9 Unspecified respiratory condition due to chemicals, gases, fumes and vapours
0.000 0.508 0.492
J68.8 Other respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.508 0.492
J68.4 Chronic respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.508 0.492
J68.3 Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.508 0.492
J68.2 Upper respiratory inflammation due to chemicals, gases, fumes and vapours, not elsewhere classified
0.000 0.508 0.492
J68.1 Acute pulmonary oedema due to chemicals, gases, fumes and vapours
0.000 0.508 0.492
J68.0 Bronchitis and pneumonitis due to chemicals, gases, fumes and vapours
0.000 0.508 0.492
I27.2 Other secondary pulmonary hypertension
0.000 0.515 0.485
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.516 0.484
J69.1 Pneumonitis due to oils and essences
0.000 0.518 0.482
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.524 0.476
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.524 0.475
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.527 0.473
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.527 0.473
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.527 0.473
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.527 0.473
I05-I09 Chronic rheumatic heart diseases
0.000 0.527 0.473
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.530 0.470
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.534 0.466
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.537 0.462
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.543 0.457
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.543 0.456
I74.8 Embolism and thrombosis of other arteries
0.000 0.544 0.456
J93.9 Pneumothorax, unspecified
0.000 0.544 0.456
J70.9 Respiratory conditions due to unspecified external agent
0.000 0.546 0.454
J70.8 Respiratory conditions due to other specified external agents
0.000 0.546 0.454
J70.4 Drug-induced interstitial lung disorder, unspecified
0.000 0.546 0.454
J70.3 Chronic drug-induced interstitial lung disorders
0.000 0.546 0.454
J70.2 Acute drug-induced interstitial lung disorders
0.000 0.546 0.454
J70.0 Acute pulmonary manifestations due to radiation
0.000 0.546 0.454
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.547 0.452
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.552 0.448
J99.8 Respiratory disorders in other diseases classified elsewhere
0.000 0.556 0.444
J67.8 Hypersensitivity pneumonitis due to other organic dusts
0.000 0.558 0.442
J67.7 Air-conditioner and humidifier lung
0.000 0.558 0.442
J67.6 Maple-bark-stripper's lung
0.000 0.558 0.442
J67.5 Mushroom-worker's lung
0.000 0.558 0.442
J67.4 Maltworker's lung
0.000 0.558 0.442
J67.3 Suberosis
0.000 0.558 0.442
J67.1 Bagassosis
0.000 0.558 0.442
J67.0 Farmer's lung
0.000 0.558 0.442
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.561 0.439
J95.8 Other postprocedural respiratory disorders
0.000 0.562 0.437
J98.8 Other specified respiratory disorders
0.000 0.564 0.436
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.564 0.435
J46 Status asthmaticus
0.000 0.567 0.433
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.567 0.433
J09-J18 Influenza and pneumonia
0.000 0.572 0.428
J85.1 Abscess of lung with pneumonia
0.000 0.573 0.427
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.574 0.426
J91 Pleural effusion in conditions classified elsewhere
0.000 0.574 0.426
J98.5 Diseases of mediastinum, not elsewhere classified
0.001 0.574 0.426
J85.3 Abscess of mediastinum
0.000 0.575 0.425
J85.0 Gangrene and necrosis of lung
0.000 0.575 0.425
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.581 0.419
J95.5 Postprocedural subglottic stenosis
0.000 0.584 0.415
J95.4 Mendelson's syndrome
0.000 0.584 0.415
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.584 0.415
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.584 0.415
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.584 0.415
J69.0 Pneumonitis due to food and vomit
0.000 0.585 0.415
I74.5 Embolism and thrombosis of iliac artery
0.000 0.585 0.415
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.587 0.413
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust
0.000 0.589 0.411
J67.2 Bird fancier's lung
0.000 0.592 0.408
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.593 0.407
J70.1 Chronic and other pulmonary manifestations due to radiation
0.000 0.599 0.400
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.601 0.399
I61.8 Other intracerebral haemorrhage
0.000 0.616 0.383
I09 Other rheumatic heart diseases
0.000 0.619 0.380
J94.1 Fibrothorax
0.000 0.620 0.380
J94.9 Pleural condition, unspecified
0.000 0.620 0.379
J94.0 Chylous effusion
0.000 0.620 0.379
J20-J22 Other acute lower respiratory infections
0.000 0.625 0.374
J94.8 Other specified pleural conditions
0.000 0.632 0.368
J85.2 Abscess of lung without pneumonia
0.000 0.637 0.363
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.643 0.357
I01.8 Other acute rheumatic heart disease
0.000 0.643 0.357
I01.2 Acute rheumatic myocarditis
0.000 0.643 0.357
I01.1 Acute rheumatic endocarditis
0.000 0.643 0.357
I01.0 Acute rheumatic pericarditis
0.000 0.643 0.357
I02.9 Rheumatic chorea without heart involvement
0.000 0.643 0.357
I02.0 Rheumatic chorea with heart involvement
0.000 0.643 0.357
I07 Rheumatic tricuspid valve diseases
0.000 0.643 0.357
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.644 0.356
I78.1 Naevus, nonneoplastic
0.000 0.645 0.355
J96.09 Acute respiratory failure; Type unspecified
0.000 0.647 0.353
J96.01 Acute respiratory failure; Type II [hypercapnic]
0.000 0.647 0.353
J96.00 Acute respiratory failure; Type I [hypoxic]
0.000 0.647 0.353
J96.19 Chronic respiratory failure; Type unspecified
0.000 0.647 0.353
J96.11 Chronic respiratory failure; Type II [hypercapnic]
0.000 0.647 0.353
J96.10 Chronic respiratory failure; Type I [hypoxic]
0.000 0.647 0.353
J96.99 Respiratory failure, unspecified; Type unspecified
0.000 0.647 0.353
J96.91 Respiratory failure unspecified; Type II [hypercapnic]
0.000 0.647 0.353
J96.90 Respiratory failure, unspecified; Type I [hypoxic]
0.000 0.647 0.353
J95.0 Tracheostomy malfunction
0.000 0.650 0.350
J18 Pneumonia, organism unspecified
0.000 0.657 0.343
J18.1 Lobar pneumonia, unspecified
0.000 0.670 0.330
I62.1 Nontraumatic extradural haemorrhage
0.000 0.670 0.329
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.672 0.327
I05 Rheumatic mitral valve diseases
0.000 0.678 0.322
J10 Influenza due to identified influenza virus
0.000 0.679 0.321
I09.9 Rheumatic heart disease, unspecified
0.000 0.686 0.314
I06 Rheumatic aortic valve diseases
0.000 0.686 0.314
I70.10 Atherosclerosis of renal artery (without gangrene)
0.001 0.691 0.309
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.000 0.693 0.307
J09 Influenza due to certain identified influenza virus
0.000 0.693 0.307
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.699 0.301
J80-J84 Other respiratory diseases principally affecting the interstitium
0.001 0.705 0.295
J17 Pneumonia in diseases classified elsewhere
0.000 0.707 0.293
J13 Pneumonia due to Streptococcus pneumoniae
0.000 0.707 0.293
J15 Bacterial pneumonia, not elsewhere classified
0.000 0.715 0.285
J12 Viral pneumonia, not elsewhere classified
0.000 0.725 0.275
I07.1 Tricuspid insufficiency
0.000 0.727 0.273
I09.8 Other specified rheumatic heart diseases
0.000 0.727 0.273
I09.2 Chronic rheumatic pericarditis
0.000 0.727 0.273
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.727 0.273
I09.0 Rheumatic myocarditis
0.000 0.727 0.273
J45 Asthma
0.000 0.727 0.273
I05.1 Rheumatic mitral insufficiency
0.000 0.735 0.265
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.000 0.739 0.261
J21 Acute bronchiolitis
0.000 0.743 0.257
J84 Other interstitial pulmonary diseases
0.000 0.744 0.256
I07.9 Tricuspid valve disease, unspecified
0.000 0.744 0.256
I07.8 Other tricuspid valve diseases
0.000 0.744 0.256
I07.2 Tricuspid stenosis with insufficiency
0.000 0.744 0.256
I07.0 Tricuspid stenosis
0.000 0.744 0.256
I99 Other and unspecified disorders of circulatory system
0.000 0.749 0.251
J14 Pneumonia due to Haemophilus influenzae
0.000 0.751 0.248
J18.2 Hypostatic pneumonia, unspecified
0.000 0.754 0.246
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.000 0.755 0.245
J20 Acute bronchitis
0.000 0.755 0.245
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.755 0.245
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.759 0.241
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.765 0.235
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.765 0.235
I05.0 Mitral stenosis
0.000 0.767 0.233
I05.8 Other mitral valve diseases
0.000 0.769 0.231
J10.8 Influenza with other manifestations, influenza virus identified
0.000 0.769 0.231
J10.0 Influenza with pneumonia, influenza virus identified
0.000 0.770 0.230
J00-J06 Acute upper respiratory infections
0.000 0.771 0.229
I95 Hypotension
0.000 0.772 0.228
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.775 0.225
I06.8 Other rheumatic aortic valve diseases
0.000 0.775 0.225
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.775 0.225
I06.1 Rheumatic aortic insufficiency
0.000 0.775 0.225
J18.8 Other pneumonia, organism unspecified
0.000 0.776 0.224
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.777 0.223
J94.2 Haemothorax
0.001 0.779 0.220
J16.8 Pneumonia due to other specified infectious organisms
0.000 0.780 0.220
J16.0 Chlamydial pneumonia
0.000 0.780 0.220
J15.2 Pneumonia due to staphylococcus
0.000 0.780 0.220
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.782 0.217
J15.8 Other bacterial pneumonia
0.000 0.783 0.217
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.784 0.216
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.784 0.216
I98.0 Cardiovascular syphilis
0.000 0.784 0.216
J15.5 Pneumonia due to Escherichia coli
0.000 0.786 0.214
I63 Cerebral infarction
0.000 0.787 0.213
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.788 0.212
I05.2 Mitral stenosis with insufficiency
0.000 0.789 0.211
J17.8 Pneumonia in other diseases classified elsewhere
0.000 0.790 0.210
F17.1 Harmful use
0.000 0.790 0.210
J15.4 Pneumonia due to other streptococci
0.000 0.790 0.210
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.000 0.792 0.208
J15.3 Pneumonia due to streptococcus, group B
0.000 0.796 0.204
I95.1 Orthostatic hypotension
0.000 0.796 0.204
J18.9 Pneumonia, unspecified
0.000 0.798 0.202
J15.9 Bacterial pneumonia, unspecified
0.000 0.799 0.201
I10-I15 Hypertensive diseases
0.000 0.799 0.201
I06.0 Rheumatic aortic stenosis
0.000 0.800 0.199
J12.8 Other viral pneumonia
0.000 0.803 0.197
J12.3 Human metapneumovirus pneumonia
0.000 0.803 0.197
J12.2 Parainfluenza virus pneumonia
0.000 0.803 0.197
J12.1 Respiratory syncytial virus pneumonia
0.000 0.803 0.197
J12.0 Adenoviral pneumonia
0.000 0.803 0.197
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.803 0.197
J45.8 Mixed asthma
0.000 0.804 0.196
J45.1 Nonallergic asthma
0.000 0.804 0.196
J11 Influenza, virus not identified
0.000 0.808 0.191
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.000 0.810 0.190
J17.1 Pneumonia in viral diseases classified elsewhere
0.000 0.812 0.187
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.813 0.187
J21.8 Acute bronchiolitis due to other specified organisms
0.000 0.815 0.185
J21.1 Acute bronchiolitis due to human metapneumovirus
0.000 0.815 0.185
J21.0 Acute bronchiolitis due to respiratory syncytial virus
0.000 0.815 0.185
J84.0 Alveolar and parietoalveolar conditions
0.000 0.816 0.184
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.816 0.184
J15.0 Pneumonia due to Klebsiella pneumoniae
0.000 0.817 0.182
I95.8 Other hypotension
0.000 0.818 0.182
J84.8 Other specified interstitial pulmonary diseases
0.000 0.818 0.182
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.819 0.181
Z72.0 Tobacco use
0.000 0.820 0.180
I05.9 Mitral valve disease, unspecified
0.000 0.820 0.180
J17.3 Pneumonia in parasitic diseases
0.000 0.822 0.177
J20.7 Acute bronchitis due to echovirus
0.000 0.824 0.176
J20.6 Acute bronchitis due to rhinovirus
0.000 0.824 0.176
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.824 0.176
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.824 0.176
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.824 0.176
J20.2 Acute bronchitis due to streptococcus
0.000 0.824 0.176
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.824 0.176
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.824 0.176
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.824 0.176
I97.0 Postcardiotomy syndrome
0.000 0.824 0.176
J20.8 Acute bronchitis due to other specified organisms
0.000 0.825 0.175
Z72.1 Alcohol use
0.000 0.826 0.174
J21.9 Acute bronchiolitis, unspecified
0.000 0.826 0.173
Z72 Problems related to lifestyle
0.000 0.827 0.173
J00 Acute nasopharyngitis [common cold]
0.000 0.828 0.172
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.829 0.170
J12.9 Viral pneumonia, unspecified
0.000 0.834 0.165
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.835 0.165
I65.1 Occlusion and stenosis of basilar artery
0.001 0.839 0.161
F17 Mental and behavioural disorders due to use of tobacco
0.000 0.839 0.161
J15.1 Pneumonia due to Pseudomonas
0.000 0.842 0.158
J20.9 Acute bronchitis, unspecified
0.000 0.846 0.154
J17.2 Pneumonia in mycoses
0.000 0.846 0.153
F17.2 Dependence syndrome
0.000 0.847 0.153
I65.2 Occlusion and stenosis of carotid artery
0.000 0.847 0.153
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.847 0.153
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.847 0.153
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.847 0.153
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.851 0.149
I15 Secondary hypertension
0.000 0.855 0.145
I13 Hypertensive heart and renal disease
0.000 0.856 0.144
J01 Acute sinusitis
0.000 0.856 0.144
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.857 0.143
I97.1 Other functional disturbances following cardiac surgery
0.000 0.862 0.138
J11.8 Influenza with other manifestations, virus not identified
0.000 0.862 0.137
I95.0 Idiopathic hypotension
0.000 0.864 0.136
Z72.2 Drug use
0.000 0.865 0.135
J04 Acute laryngitis and tracheitis
0.000 0.866 0.134
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.869 0.131
J03 Acute tonsillitis
0.000 0.869 0.131
J02 Acute pharyngitis
0.000 0.872 0.127
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.874 0.126
J45.0 Predominantly allergic asthma
0.000 0.875 0.125
Z72.4 Inappropriate diet and eating habits
0.000 0.875 0.125
Z72.6 Gambling and betting
0.000 0.875 0.124
Z72.5 High-risk sexual behaviour
0.000 0.875 0.124
Z72.3 Lack of physical exercise
0.000 0.875 0.124
Z72.8 Other problems related to lifestyle
0.000 0.877 0.123
J05.1 Acute epiglottitis
0.000 0.881 0.119
J81 Pulmonary oedema
0.000 0.881 0.118
J05.0 Acute obstructive laryngitis [croup]
0.000 0.881 0.118
I15.1 Hypertension secondary to other renal disorders
0.000 0.883 0.116
F17.8 Other mental and behavioural disorders
0.000 0.884 0.115
F17.7 Residual and late-onset psychotic disorder
0.000 0.884 0.115
F17.6 Amnesic syndrome
0.000 0.884 0.115
F17.5 Psychotic disorder
0.000 0.884 0.115
F17.4 Withdrawal state with delirium
0.000 0.884 0.115
F17.3 Withdrawal state
0.000 0.884 0.115
J47 Bronchiectasis
0.000 0.885 0.115
Z72.9 Problem related to lifestyle, unspecified
0.000 0.886 0.113
F17.9 Unspecified mental and behavioural disorder
0.000 0.890 0.110
I11 Hypertensive heart disease
0.000 0.890 0.110
J11.0 Influenza with pneumonia, virus not identified
0.001 0.891 0.109
F17.0 Acute intoxication
0.000 0.891 0.108
I15.9 Seconday hypertension, unspecified
0.000 0.893 0.107
I87 Other disorders of veins
0.000 0.894 0.106
J01.0 Acute maxillary sinusitis
0.000 0.895 0.105
I15.8 Other secondary hypertension
0.000 0.896 0.104
I15.2 Hypertension secondary to endocrine disorders
0.000 0.896 0.104
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.896 0.103
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.896 0.103
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.896 0.103
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.896 0.103
J01.8 Other acute sinusitis
0.000 0.897 0.103
J01.4 Acute pansinusitis
0.000 0.897 0.103
J01.3 Acute sphenoidal sinusitis
0.000 0.897 0.103
J01.1 Acute frontal sinusitis
0.000 0.897 0.103
I81 Portal vein thrombosis
0.000 0.897 0.103
J18.0 Bronchopneumonia, unspecified
0.000 0.898 0.102
I88 Nonspecific lymphadenitis
0.000 0.898 0.102
J82 Pulmonary eosinophilia, not elsewhere classified
0.002 0.899 0.099
I12 Hypertensive renal disease
0.000 0.900 0.100
I85 Oesophageal varices
0.000 0.901 0.099
J01.2 Acute ethmoidal sinusitis
0.000 0.902 0.098
J04.2 Acute laryngotracheitis
0.000 0.904 0.096
J02.0 Streptococcal pharyngitis
0.000 0.905 0.095
I87.1 Compression of vein
0.000 0.905 0.095
J03.8 Acute tonsillitis due to other specified organisms
0.000 0.906 0.094
J03.0 Streptococcal tonsillitis
0.000 0.906 0.094
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.906 0.094
J04.1 Acute tracheitis
0.000 0.907 0.093
J02.8 Acute pharyngitis due to other specified organisms
0.000 0.908 0.092
I80 Phlebitis and thrombophlebitis
0.000 0.911 0.089
E11 Non-insulin-dependent diabetes mellitus
0.000 0.911 0.089
J01.9 Acute sinusitis, unspecified
0.000 0.912 0.088
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.912 0.088
I85.0 Oesophageal varices with bleeding
0.000 0.912 0.088
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.913 0.087
E11.3 With ophthalmic complications
0.000 0.913 0.087
I87.8 Other specified disorders of veins
0.000 0.914 0.086
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.915 0.085
C34.1 Upper lobe, bronchus or lung
0.000 0.916 0.084
I63.8 Other cerebral infarction
0.000 0.917 0.083
I15.0 Renovascular hypertension
0.000 0.918 0.082
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.918 0.081
J11.1 Influenza with other respiratory manifestations, virus not identified
0.001 0.919 0.080
E11.0 With coma
0.000 0.920 0.080
E11.2 With renal complications
0.000 0.921 0.079

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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