TreeWAS – Variant ID: rs3819299

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H20.9 Iridocyclitis, unspecified	1.000	0.000	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	1.000	0.000	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	1.000	0.000	0.000
M45 Ankylosing spondylitis	1.000	0.000	0.000
M45-M49 Spondylopathies	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
H20 Iridocyclitis	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
M07 Psoriatic and enteropathic arthropathies	0.999	0.001	0.000
M07.3 Other psoriatic arthropathies	0.999	0.001	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.999	0.001	0.000
L40.5 Arthropathic psoriasis	0.997	0.003	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.003	0.997
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.997	0.003	0.000
L40 Psoriasis	0.996	0.004	0.000
H40-H42 Glaucoma	0.996	0.004	0.000
O00-O08 Pregnancy with abortive outcome	0.996	0.004	0.000
L40-L45 Papulosquamous disorders	0.996	0.004	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.994	0.006	0.000
H40 Glaucoma	0.993	0.007	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.992	0.008	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.985	0.015	0.000
H40.9 Glaucoma, unspecified	0.983	0.017	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.982	0.018	0.000
O04 Medical abortion	0.976	0.024	0.000
M47 Spondylosis	0.972	0.028	0.000
O03 Spontaneous abortion	0.971	0.029	0.000
M47.9 Spondylosis, unspecified	0.967	0.033	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.967	0.033	0.000
E03 Other hypothyroidism	0.000	0.035	0.965
M00-M03 Infectious arthropathies	0.965	0.035	0.000
H40.0 Glaucoma suspect	0.964	0.036	0.000
M20-M25 Other joint disorders	0.963	0.037	0.000
O03.4 Incomplete, without complication	0.953	0.047	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.949	0.051	0.000
M65-M68 Disorders of synovium and tendon	0.948	0.052	0.000
M46 Other inflammatory spondylopathies	0.945	0.055	0.000
O04.9 Complete or unspecified, without complication	0.942	0.058	0.000
E00-E07 Disorders of thyroid gland	0.000	0.062	0.938
M24 Other specific joint derangements	0.937	0.063	0.000
H20.0 Acute and subacute iridocyclitis	0.932	0.068	0.000
M06.0 Seronegative rheumatoid arthritis	0.930	0.070	0.000
M86-M90 Other osteopathies	0.924	0.076	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.076	0.924
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.923	0.077	0.000
M65 Synovitis and tenosynovitis	0.917	0.083	0.000
M02 Reactive arthropathies	0.912	0.088	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.906	0.094	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.106	0.894
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.894	0.106	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.884	0.116	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.882	0.118	0.000
M24.1 Other articular cartilage disorders	0.880	0.120	0.000
O80-O84 Delivery	0.876	0.124	0.000
H20.1 Chronic iridocyclitis	0.868	0.132	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.867	0.133	0.000
Chapter V Mental and behavioural disorders	0.866	0.134	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.863	0.137	0.000
M21 Other acquired deformities of limbs	0.860	0.140	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.859	0.141	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.859	0.141	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.858	0.142	0.000
M02.3 Reiter's disease	0.857	0.143	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.855	0.145	0.000
Chapter XXII Codes for special purposes	0.853	0.147	0.000
H01 Other inflammation of eyelid	0.851	0.149	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.851	0.149	0.000
M06.4 Inflammatory polyarthropathy	0.849	0.151	0.000
O60-O75 Complications of labour and delivery	0.846	0.154	0.000
M34 Systemic sclerosis	0.843	0.157	0.000
L43 Lichen planus	0.838	0.162	0.000
M00 Pyogenic arthritis	0.836	0.164	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.835	0.165	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.834	0.166	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.831	0.169	0.000
H50 Other strabismus	0.830	0.170	0.000
H01.0 Blepharitis	0.823	0.177	0.000
H10-H13 Disorders of conjunctiva	0.820	0.180	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.819	0.181	0.000
M02.39 Reiter's disease (Site unspecified)	0.818	0.182	0.000
H30-H36 Disorders of choroid and retina	0.813	0.187	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.813	0.187	0.000
L40.8 Other psoriasis	0.813	0.187	0.000
M86 Osteomyelitis	0.813	0.187	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.809	0.191	0.000
H40.5 Glaucoma secondary to other eye disorders	0.807	0.193	0.000
M25 Other joint disorders, not elsewhere classified	0.807	0.193	0.000
F30-F39 Mood [affective] disorders	0.800	0.200	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.201	0.799
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.796	0.204	0.000
M65.8 Other synovitis and tenosynovitis	0.794	0.206	0.000
M89 Other disorders of bone	0.794	0.206	0.000
E07 Other disorders of thyroid	0.000	0.207	0.792
K90.0 Coeliac disease	0.000	0.208	0.792
M49 Spondylopathies in diseases classified elsewhere	0.786	0.213	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.786	0.214	0.000
M05 Seropositive rheumatoid arthritis	0.786	0.214	0.000
M25.4 Effusion of joint	0.785	0.215	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.784	0.216	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.782	0.218	0.000
F60-F69 Disorders of adult personality and behaviour	0.777	0.223	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.776	0.224	0.000
Chapter VI Diseases of the nervous system	0.775	0.225	0.000
M24.0 Loose body in joint	0.771	0.229	0.000
O80 Single spontaneous delivery	0.771	0.229	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.768	0.232	0.000
L50-L54 Urticaria and erythema	0.766	0.234	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.765	0.235	0.000
H55-H59 Other disorders of eye and adnexa	0.764	0.236	0.000
O04.4 Incomplete, without complication	0.763	0.237	0.000
M25.46 Effusion of joint (Lower leg)	0.760	0.240	0.000
L42 Pityriasis rosea	0.760	0.240	0.000
M91-M94 Chondropathies	0.759	0.241	0.000
O85-O92 Complications predominantly related to the puerperium	0.757	0.243	0.000
M60-M63 Disorders of muscles	0.755	0.245	0.000
H16 Keratitis	0.755	0.245	0.000
H50.0 Convergent concomitant strabismus	0.753	0.247	0.000
O00 Ectopic pregnancy	0.753	0.247	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.752	0.248	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.751	0.248	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.748	0.251	0.000
O72 Postpartum haemorrhage	0.748	0.252	0.000
M00.9 Pyogenic arthritis, unspecified	0.744	0.256	0.000
H50.9 Strabismus, unspecified	0.744	0.256	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.742	0.258	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.742	0.258	0.000
M21.3 Wrist or foot drop (acquired)	0.740	0.260	0.000
H21 Other disorders of iris and ciliary body	0.739	0.261	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.261	0.739
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.739	0.261	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.738	0.262	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.737	0.263	0.000
E03.8 Other specified hypothyroidism	0.000	0.263	0.736
M14 Arthropathies in other diseases classified elsewhere	0.735	0.265	0.000
H33 Retinal detachments and breaks	0.734	0.266	0.000
M24.5 Contracture of joint	0.733	0.267	0.000
M02.9 Reactive arthopathy, unspecified	0.731	0.269	0.000
Chapter I Certain infectious and parasitic diseases	0.727	0.273	0.000
E06 Thyroiditis	0.000	0.274	0.725
L43.9 Lichen planus, unspecified	0.725	0.275	0.000
M88 Paget's disease of bone [osteitis deformans]	0.724	0.276	0.000
G20-G26 Extrapyramidal and movement disorders	0.719	0.281	0.000
H05 Disorders of orbit	0.718	0.282	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.717	0.283	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.717	0.283	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.717	0.283	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.717	0.283	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.717	0.283	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.717	0.283	0.000
M12 Other specific arthropathies	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M08 Juvenile arthritis	0.717	0.283	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
H20.8 Other iridocyclitis	0.717	0.283	0.000
H20.2 Lens-induced iridocyclitis	0.717	0.283	0.000
M06.8 Other specified rheumatoid arthritis	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.717	0.283	0.000
H17 Corneal scars and opacities	0.717	0.283	0.000
H15 Disorders of sclera	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
M07.6 Other enteropathic arthropathies	0.717	0.283	0.000
M07.5 Arthropathy in ulcerative colitis	0.717	0.283	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.717	0.283	0.000
M07.2 Psoriatic spondylitis	0.717	0.283	0.000
M07.1 Arthritis mutilans	0.717	0.283	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.717	0.283	0.000
M07.38 Other psoriatic arthropathies (Other)	0.716	0.283	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.716	0.283	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.716	0.283	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.716	0.283	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.716	0.283	0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.714	0.286	0.000
L40.4 Guttate psoriasis	0.714	0.286	0.000
L40.3 Pustulosis palmaris et plantaris	0.714	0.286	0.000
L40.2 Acrodermatitis continua	0.714	0.286	0.000
L40.1 Generalised pustular psoriasis	0.714	0.286	0.000
H42 Glaucoma in diseases classified elsewhere	0.714	0.286	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.714	0.286	0.000
O07 Failed attempted abortion	0.714	0.286	0.000
O06 Unspecified abortion	0.714	0.286	0.000
O05 Other abortion	0.714	0.286	0.000
O01 Hydatidiform mole	0.714	0.286	0.000
L44 Other papulosquamous disorders	0.714	0.286	0.000
L41 Parapsoriasis	0.714	0.286	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.714	0.286	0.000
L10-L14 Bullous disorders	0.713	0.287	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.712	0.288	0.000
F60 Specific personality disorders	0.712	0.288	0.000
H40.6 Glaucoma secondary to drugs	0.712	0.288	0.000
H40.4 Glaucoma secondary to eye inflammation	0.712	0.288	0.000
H40.3 Glaucoma secondary to eye trauma	0.712	0.288	0.000
L40.0 Psoriasis vulgaris	0.710	0.289	0.000
M86.9 Osteomyelitis, unspecified	0.709	0.291	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.706	0.294	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.706	0.294	0.000
M33 Dermatopolymyositis	0.705	0.295	0.000
O03.9 Complete or unspecified, without complication	0.703	0.297	0.000
F31 Bipolar affective disorder	0.702	0.298	0.000
M34.9 Systemic sclerosis, unspecified	0.701	0.299	0.000
O04.8 Complete or unspecified, with other and unspecified complications	0.700	0.300	0.000
O04.7 Complete or unspecified, complicated by embolism	0.700	0.300	0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.700	0.300	0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.700	0.300	0.000
O04.3 Incomplete, with other and unspecified complications	0.700	0.300	0.000
O04.2 Incomplete, complicated by embolism	0.700	0.300	0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.700	0.300	0.000
M89.9 Disorder of bone, unspecified	0.700	0.300	0.000
O21 Excessive vomiting in pregnancy	0.698	0.302	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.698	0.302	0.000
O70 Perineal laceration during delivery	0.698	0.302	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.697	0.303	0.000
Q80-Q89 Other congenital malformations	0.697	0.303	0.000
G90-G99 Other disorders of the nervous system	0.696	0.304	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.696	0.304	0.000
O03.7 Complete or unspecified, complicated by embolism	0.696	0.304	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.696	0.304	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.696	0.304	0.000
O03.3 Incomplete, with other and unspecified complications	0.696	0.304	0.000
O03.2 Incomplete, complicated by embolism	0.696	0.304	0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.696	0.304	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.696	0.304	0.000
U88 Agent resistant to multiple antibiotics	0.696	0.304	0.000
M06.3 Rheumatoid nodule	0.693	0.307	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.693	0.307	0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.693	0.307	0.000
M47.94 Spondylosis, unspecified (Thoracic region)	0.693	0.307	0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.693	0.307	0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.693	0.307	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.693	0.307	0.000
E03.5 Myxoedema coma	0.000	0.308	0.692
E03.4 Atrophy of thyroid (acquired)	0.000	0.308	0.692
E03.3 Postinfectious hypothyroidism	0.000	0.308	0.692
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.308	0.692
E03.1 Congenital hypothyroidism without goitre	0.000	0.308	0.692
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.308	0.692
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.692	0.308	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.692	0.308	0.000
M21.1 Varus deformity, not elsewhere classified	0.692	0.308	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.690	0.310	0.000
M32 Systemic lupus erythematosus	0.690	0.310	0.000
M30 Polyarteritis nodosa and related conditions	0.690	0.310	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.689	0.311	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.689	0.311	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.688	0.312	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.312	0.688
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.688	0.312	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.687	0.313	0.000
M47.1 Other spondylosis with myelopathy	0.683	0.317	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.683	0.317	0.000
H33.0 Retinal detachment with retinal break	0.682	0.318	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.679	0.320	0.000
M11 Other crystal arthropathies	0.679	0.321	0.000
M67 Other disorders of synovium and tendon	0.679	0.321	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.679	0.321	0.000
M46.8 Other specified inflammatory spondylopathies	0.678	0.322	0.000
M46.5 Other infective spondylopathies	0.678	0.322	0.000
M46.4 Discitis, unspecified	0.678	0.322	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.678	0.322	0.000
M46.2 Osteomyelitis of vertebra	0.678	0.322	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.678	0.322	0.000
M46.0 Spinal enthesopathy	0.678	0.322	0.000
O81 Single delivery by forceps and vacuum extractor	0.675	0.325	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.327	0.672
E00 Congenital iodine-deficiency syndrome	0.000	0.327	0.672
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.327	0.672
M24.9 Joint derangement, unspecified	0.672	0.328	0.000
M24.7 Protrusio acetabuli	0.672	0.328	0.000
M24.6 Ankylosis of joint	0.672	0.328	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.672	0.328	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.671	0.329	0.000
G24 Dystonia	0.671	0.329	0.000
M13 Other arthritis	0.671	0.329	0.000
G91 Hydrocephalus	0.668	0.332	0.000
H10 Conjunctivitis	0.668	0.332	0.000
F99-F99 Unspecified mental disorder	0.668	0.332	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.667	0.332	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.667	0.333	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.667	0.333	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.667	0.333	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.667	0.333	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.667	0.333	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.667	0.333	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.667	0.333	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.667	0.333	0.000
O20 Haemorrhage in early pregnancy	0.665	0.335	0.000
Q60-Q64 Congenital malformations of the urinary system	0.665	0.335	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.664	0.336	0.000
B95-B98 Bacterial, viral and other infectious agents	0.663	0.337	0.000
E05.8 Other thyrotoxicosis	0.000	0.337	0.662
E05.5 Thyroid crisis or storm	0.000	0.337	0.662
E05.4 Thyrotoxicosis factitia	0.000	0.337	0.662
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.337	0.662
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.337	0.662
O75.0 Maternal distress during labour and delivery	0.662	0.338	0.000
M34.1 CR(E)ST syndrome	0.661	0.339	0.000
M90 Osteopathies in diseases classified elsewhere	0.660	0.340	0.000
H40.8 Other glaucoma	0.658	0.342	0.000
F32 Depressive episode	0.658	0.342	0.000
M65.2 Calcific tendinitis	0.657	0.343	0.000
M65.1 Other infective (teno)synovitis	0.657	0.343	0.000
M65.0 Abscess of tendon sheath	0.657	0.343	0.000
O80.9 Single spontaneous delivery, unspecified	0.656	0.344	0.000
M34.8 Other forms of systemic sclerosis	0.656	0.344	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.655	0.345	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.654	0.346	0.000
M02.8 Other reactive arthropathies	0.654	0.346	0.000
M02.2 Postimmunisation arthropathy	0.654	0.346	0.000
M02.1 Postdysenteric arthropathy	0.654	0.346	0.000
M02.0 Arthropathy following intestinal bypass	0.654	0.346	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.653	0.347	0.000
O75.8 Other specified complications of labour and delivery	0.652	0.348	0.000
H01.9 Inflammation of eyelid, unspecified	0.651	0.349	0.000
M24.2 Disorder of ligament	0.650	0.350	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.650	0.350	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.650	0.350	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.650	0.350	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.650	0.350	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.650	0.350	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.650	0.350	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.650	0.350	0.000
M21.4 Flat foot [pes planus] (acquired)	0.649	0.350	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.649	0.351	0.000
M21.2 Flexion deformity	0.648	0.352	0.000
H02 Other disorders of eyelid	0.648	0.352	0.000
H40.1 Primary open-angle glaucoma	0.647	0.353	0.000
F80-F89 Disorders of psychological development	0.645	0.355	0.000
F30 Manic episode	0.643	0.357	0.000
G91.9 Hydrocephalus, unspecified	0.642	0.358	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.641	0.359	0.000
M47.2 Other spondylosis with radiculopathy	0.640	0.360	0.000
M22 Disorders of patella	0.638	0.362	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.636	0.364	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.634	0.366	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.634	0.366	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.634	0.366	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.634	0.366	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.634	0.366	0.000
M86.6 Other chronic osteomyelitis	0.634	0.366	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.633	0.366	0.000
O70.1 Second degree perineal laceration during delivery	0.633	0.367	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.632	0.368	0.000
M24.02 Loose body in joint (Upper arm)	0.632	0.368	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.631	0.369	0.000
M24.18 Other articular cartilage disorders (Other)	0.631	0.369	0.000
M24.14 Other articular cartilage disorders (Hand)	0.631	0.369	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.631	0.369	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.631	0.369	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.370	0.630
M65.4 Radial styloid tenosynovitis [de Quervain]	0.630	0.370	0.000
M50-M54 Other dorsopathies	0.630	0.370	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.629	0.371	0.000
O62 Abnormalities of forces of labour	0.629	0.371	0.000
O84 Multiple delivery	0.628	0.372	0.000
O83 Other assisted single delivery	0.628	0.372	0.000
M40-M43 Deforming dorsopathies	0.628	0.372	0.000
G25 Other extrapyramidal and movement disorders	0.627	0.373	0.000
H50.1 Divergent concomitant strabismus	0.627	0.373	0.000
O80.0 Spontaneous vertex delivery	0.626	0.374	0.000
M66 Spontaneous rupture of synovium and tendon	0.626	0.374	0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.624	0.376	0.000
H11 Other disorders of conjunctiva	0.623	0.377	0.000
Q12 Congenital lens malformations	0.623	0.377	0.000
O82 Single delivery by Caesarean section	0.623	0.377	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.622	0.378	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.378	0.622
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.621	0.378	0.000
Q35-Q37 Cleft lip and cleft palate	0.621	0.378	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.621	0.378	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.621	0.379	0.000
F70-F79 Mental retardation	0.621	0.379	0.000
O72.0 Third-stage haemorrhage	0.621	0.379	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.621	0.379	0.000
M25.47 Effusion of joint (Ankle and foot)	0.619	0.381	0.000
H51 Other disorders of binocular movement	0.619	0.381	0.000
H31 Other disorders of choroid	0.619	0.381	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.619	0.381	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.618	0.381	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.618	0.382	0.000
C79 Secondary malignant neoplasm of other sites	0.000	0.383	0.617
M21.9 Acquired deformity of limb, unspecified	0.617	0.383	0.000
M21.8 Other specified acquired deformities of limbs	0.617	0.383	0.000
M21.7 Unequal limb length (acquired)	0.617	0.383	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.384	0.616
M02.38 Reiter's disease (Other)	0.614	0.385	0.000
M02.37 Reiter's disease (Ankle and foot)	0.614	0.385	0.000
M02.36 Reiter's disease (Lower leg)	0.614	0.385	0.000
M02.35 Reiter's disease (Pelvic region and thigh)	0.614	0.385	0.000
M02.34 Reiter's disease (Hand)	0.614	0.385	0.000
M02.33 Reiter's disease (Forearm)	0.614	0.385	0.000
M02.32 Reiter's disease (Upper arm)	0.614	0.385	0.000
M02.31 Reiter's disease (Shoulder region)	0.614	0.385	0.000
M02.30 Reiter's disease (Multiple sites)	0.614	0.385	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.613	0.387	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.613	0.387	0.000
G24.9 Dystonia, unspecified	0.611	0.389	0.000
H02.0 Entropion and trichiasis of eyelid	0.611	0.389	0.000
O71 Other obstetric trauma	0.610	0.390	0.000
H01.1 Non-infectious dermatoses of eyelid	0.610	0.390	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.609	0.391	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.609	0.391	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.609	0.391	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.609	0.391	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.609	0.391	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.609	0.391	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.609	0.391	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.609	0.391	0.000
M25.5 Pain in joint	0.608	0.392	0.000
Q76 Congenital malformations of spine and bony thorax	0.608	0.392	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.607	0.393	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.607	0.393	0.000
L52 Erythema nodosum	0.607	0.393	0.000
O74 Complications of anaesthesia during labour and delivery	0.606	0.393	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.606	0.393	0.000
O60 Preterm delivery	0.606	0.393	0.000
O00.9 Ectopic pregnancy, unspecified	0.606	0.394	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.606	0.394	0.000
G03 Meningitis due to other and unspecified causes	0.605	0.395	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.605	0.395	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.605	0.395	0.000
M34.0 Progressive systemic sclerosis	0.605	0.395	0.000
H33.2 Serous retinal detachment	0.604	0.396	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.604	0.396	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.603	0.397	0.000
O23 Infections of genito-urinary tract in pregnancy	0.603	0.397	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.603	0.397	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.602	0.397	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.602	0.398	0.000
L50 Urticaria	0.602	0.398	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.602	0.398	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.601	0.399	0.000
M02.90 Reactive arthropathy, unspecified (Multiple sites)	0.601	0.399	0.000
L43.8 Other lichen planus	0.601	0.399	0.000
L43.3 Subacute (active) lichen planus	0.601	0.399	0.000
L43.2 Lichenoid drug reaction	0.601	0.399	0.000
L43.1 Bullous lichen planus	0.601	0.399	0.000
L43.0 Hypertrophic lichen planus	0.601	0.399	0.000
M00.8 Arthritis and polyarthritis due to other specified bacterial agents	0.600	0.400	0.000
M00.2 Other streptococcal arthritis and polyarthritis	0.600	0.400	0.000
M00.1 Pneumococcal arthritis and polyarthritis	0.600	0.400	0.000
M00.0 Staphylococcal arthritis and polyarthritis	0.600	0.400	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.599	0.401	0.000
B99-B99 Other infectious diseases	0.599	0.401	0.000
M21.6 Other acquired deformities of ankle and foot	0.598	0.401	0.000
M87 Osteonecrosis	0.597	0.402	0.000
H50.5 Heterophoria	0.597	0.403	0.000
C77.2 Intra-abdominal lymph nodes	0.000	0.403	0.597
M24.13 Other articular cartilage disorders (Forearm)	0.596	0.404	0.000
F60.9 Personality disorder, unspecified	0.596	0.404	0.000
H50.8 Other specified strabismus	0.595	0.405	0.000
H50.6 Mechanical strabismus	0.595	0.405	0.000
H50.4 Other and unspecified heterotropia	0.595	0.405	0.000
H50.3 Intermittent heterotropia	0.595	0.405	0.000
H50.2 Vertical strabismus	0.595	0.405	0.000
M21.0 Valgus deformity, not elsewhere classified	0.592	0.408	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.592	0.408	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.592	0.408	0.000
H05.0 Acute inflammation of orbit	0.591	0.409	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.590	0.410	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.589	0.411	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.588	0.412	0.000
L40.9 Psoriasis, unspecified	0.588	0.412	0.000
C80 Malignant neoplasm without specification of site	0.000	0.413	0.586
M24.56 Contracture of joint (Lower leg)	0.586	0.413	0.000
M24.07 Loose body in joint (Ankle and foot)	0.586	0.414	0.000
H18 Other disorders of cornea	0.585	0.415	0.000
O66 Other obstructed labour	0.585	0.415	0.000
Q18 Other congenital malformations of face and neck	0.583	0.417	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.583	0.417	0.000
H30 Chorioretinal inflammation	0.583	0.417	0.000
M92 Other juvenile osteochondrosis	0.583	0.417	0.000
M86.8 Other osteomyelitis	0.583	0.417	0.000
M86.5 Other chronic haematogenous osteomyelitis	0.583	0.417	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.583	0.417	0.000
M86.3 Chronic multifocal osteomyelitis	0.583	0.417	0.000
M86.2 Subacute osteomyelitis	0.583	0.417	0.000
M86.1 Other acute osteomyelitis	0.583	0.417	0.000
M86.0 Acute haematogenous osteomyelitis	0.583	0.417	0.000
Q50-Q56 Congenital malformations of genital organs	0.582	0.418	0.000
F60.5 Anankastic personality disorder	0.581	0.419	0.000
O21.9 Vomiting of pregnancy, unspecified	0.581	0.419	0.000
M94 Other disorders of cartilage	0.581	0.419	0.000
M88.9 Paget's disease of bone, unspecified	0.580	0.419	0.000
M65.3 Trigger finger	0.580	0.420	0.000
M62 Other disorders of muscle	0.580	0.420	0.000
O90 Complications of the puerperium, not elsewhere classified	0.580	0.420	0.000
O29 Complications of anaesthesia during pregnancy	0.580	0.420	0.000
O22 Venous complications in pregnancy	0.580	0.420	0.000
O25 Malnutrition in pregnancy	0.580	0.420	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.421	0.579
B50-B64 Protozoal diseases	0.579	0.421	0.000
H16.0 Corneal ulcer	0.579	0.421	0.000
M25.2 Flail joint	0.578	0.421	0.000
M25.1 Fistula of joint	0.578	0.421	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations