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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3828840
log Bayes Factor = 272.834
Chromosome 6   position 32,520,907  (GRCh37) Explore rs3828840 on Ensembl!
Variant rs3828840 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
E10.1 With ketoacidosis
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
H36.0 Diabetic retinopathy
1.000 0.000 0.000
J45.9 Asthma, unspecified
1.000 0.000 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
G35 Multiple sclerosis
0.000 0.000 1.000
K51 Ulcerative colitis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E14.9 Without complications
1.000 0.000 0.000
C44.3 Skin of other and unspecified parts of face
0.000 0.000 1.000
E11.9 Without complications
1.000 0.000 0.000
Z93.2 Ileostomy status
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90 Intestinal malabsorption
1.000 0.000 0.000
E10.4 With neurological complications
0.999 0.001 0.000
K70-K77 Diseases of liver
0.999 0.001 0.000
H36 Retinal disorders in diseases classified elsewhere
0.999 0.001 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.999 0.001 0.000
H30-H36 Disorders of choroid and retina
0.999 0.001 0.000
K90-K93 Other diseases of the digestive system
0.999 0.001 0.000
K51.4 Pseudopolyposis of colon
0.000 0.001 0.999
J45 Asthma
0.998 0.002 0.000
C44 Other malignant neoplasms of skin
0.000 0.002 0.998
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.998 0.002 0.000
J40-J47 Chronic lower respiratory diseases
0.997 0.003 0.000
Chapter VII Diseases of the eye and adnexa
0.997 0.003 0.000
Chapter X Diseases of the respiratory system
0.997 0.003 0.000
E14.3 With ophthalmic complications
0.996 0.004 0.000
K51.8 Other ulcerative colitis
0.000 0.004 0.996
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.005 0.995
G35-G37 Demyelinating diseases of the central nervous system
0.001 0.008 0.991
E05.9 Thyrotoxicosis, unspecified
0.991 0.009 0.000
H43-H45 Disorders of vitreous body and globe
0.990 0.010 0.000
E11.3 With ophthalmic complications
0.989 0.011 0.000
G37 Other demyelinating diseases of central nervous system
0.000 0.011 0.989
K86 Other diseases of pancreas
0.989 0.011 0.000
H43 Disorders of vitreous body
0.989 0.011 0.000
E11.1 With ketoacidosis
0.988 0.012 0.000
D60-D64 Aplastic and other anaemias
0.988 0.012 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.988 0.012 0.000
D64.9 Anaemia, unspecified
0.988 0.012 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.988 0.012 0.000
D64 Other anaemias
0.987 0.013 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.014 0.986
E10.5 With peripheral circulatory complications
0.985 0.015 0.000
K51.2 Ulcerative (chronic) proctitis
0.000 0.017 0.983
K74 Fibrosis and cirrhosis of liver
0.982 0.018 0.000
K75 Other inflammatory liver diseases
0.981 0.019 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.980 0.020 0.000
K75.4 Autoimmune hepatitis
0.977 0.023 0.000
N00-N08 Glomerular diseases
0.975 0.025 0.000
D80-D89 Certain disorders involving the immune mechanism
0.974 0.026 0.000
K86.1 Other chronic pancreatitis
0.972 0.028 0.000
Chapter XIV Diseases of the genitourinary system
0.972 0.028 0.000
Chapter VIII Diseases of the ear and mastoid process
0.970 0.030 0.000
H60-H62 Diseases of external ear
0.968 0.032 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.965 0.035 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.964 0.036 0.000
D86 Sarcoidosis
0.963 0.037 0.000
H61 Other disorders of external ear
0.962 0.038 0.000
H43.3 Other vitreous opacities
0.961 0.039 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.961 0.039 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.960 0.040 0.000
L90.0 Lichen sclerosus et atrophicus
0.959 0.041 0.000
E10.8 With unspecified complications
0.958 0.042 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.958 0.042 0.000
L90 Atrophic disorders of skin
0.957 0.043 0.000
N05 Unspecified nephritic syndrome
0.957 0.043 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.956 0.044 0.000
H61.0 Perichondritis of external ear
0.956 0.044 0.000
Chapter IX Diseases of the circulatory system
0.956 0.044 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.954 0.046 0.000
I10-I15 Hypertensive diseases
0.954 0.046 0.000
H34 Retinal vascular occlusions
0.952 0.048 0.000
E11.5 With peripheral circulatory complications
0.952 0.048 0.000
E20-E35 Disorders of other endocrine glands
0.952 0.048 0.000
C44.7 Skin of lower limb, including hip
0.000 0.050 0.950
J33 Nasal polyp
0.948 0.052 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.947 0.053 0.000
E11.2 With renal complications
0.946 0.054 0.000
J33.9 Nasal polyp, unspecified
0.946 0.054 0.000
K90.9 Intestinal malabsorption, unspecified
0.944 0.056 0.000
J43 Emphysema
0.941 0.059 0.000
I10 Essential (primary) hypertension
0.940 0.060 0.000
D50-D53 Nutritional anaemias
0.939 0.061 0.000
H43.8 Other disorders of vitreous body
0.939 0.061 0.000
E06 Thyroiditis
0.935 0.065 0.000
N04 Nephrotic syndrome
0.935 0.065 0.000
E10.0 With coma
0.933 0.067 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.068 0.932
K86.3 Pseudocyst of pancreas
0.930 0.070 0.000
J95-J99 Other diseases of the respiratory system
0.929 0.071 0.000
C44.1 Skin of eyelid, including canthus
0.000 0.072 0.928
Q80-Q89 Other congenital malformations
0.927 0.073 0.000
J33.8 Other polyp of sinus
0.925 0.075 0.000
J86 Pyothorax
0.923 0.077 0.000
H35 Other retinal disorders
0.923 0.077 0.000
D50 Iron deficiency anaemia
0.923 0.077 0.000
J46 Status asthmaticus
0.921 0.079 0.000
D50.9 Iron deficiency anaemia, unspecified
0.920 0.080 0.000
L40-L45 Papulosquamous disorders
0.920 0.080 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.918 0.082 0.000
L80 Vitiligo
0.916 0.084 0.000
E10.2 With renal complications
0.915 0.085 0.000
Q60-Q64 Congenital malformations of the urinary system
0.915 0.085 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.913 0.087 0.000
J33.0 Polyp of nasal cavity
0.913 0.087 0.000
J43.9 Emphysema, unspecified
0.912 0.088 0.000
E11.6 With other specified complications
0.911 0.089 0.000
L92.0 Granuloma annulare
0.911 0.089 0.000
C44.5 Skin of trunk
0.000 0.090 0.910
D86.9 Sarcoidosis, unspecified
0.910 0.090 0.000
H34.8 Other retinal vascular occlusions
0.910 0.090 0.000
H43.1 Vitreous haemorrhage
0.909 0.091 0.000
E03.8 Other specified hypothyroidism
0.907 0.093 0.000
E24 Cushing's syndrome
0.906 0.094 0.000
L40 Psoriasis
0.906 0.094 0.000
K51.5 Mucosal proctocolitis
0.000 0.097 0.903
N17-N19 Renal failure
0.903 0.097 0.000
E13 Other specified diabetes mellitus
0.900 0.100 0.000
N40-N51 Diseases of male genital organs
0.899 0.101 0.000
N18 Chronic renal failure
0.897 0.103 0.000
L40.9 Psoriasis, unspecified
0.892 0.108 0.000
K74.3 Primary biliary cirrhosis
0.889 0.111 0.000
K72 Hepatic failure, not elsewhere classified
0.889 0.111 0.000
K73 Chronic hepatitis, not elsewhere classified
0.888 0.112 0.000
N18.9 Chronic renal failure, unspecified
0.888 0.112 0.000
N48 Other disorders of penis
0.884 0.116 0.000
K74.6 Other and unspecified cirrhosis of liver
0.884 0.116 0.000
J30-J39 Other diseases of upper respiratory tract
0.882 0.118 0.000
I15 Secondary hypertension
0.881 0.119 0.000
E07 Other disorders of thyroid
0.880 0.120 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.880 0.120 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.876 0.124 0.000
D86.3 Sarcoidosis of skin
0.875 0.125 0.000
J98 Other respiratory disorders
0.872 0.128 0.000
E14.1 With ketoacidosis
0.868 0.132 0.000
E83 Disorders of mineral metabolism
0.000 0.133 0.867
E16.0 Drug-induced hypoglycaemia without coma
0.866 0.134 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.866 0.134 0.000
E10.6 With other specified complications
0.863 0.137 0.000
Q61 Cystic kidney disease
0.859 0.141 0.000
N04.9 Unspecified
0.859 0.141 0.000
K86.8 Other specified diseases of pancreas
0.857 0.143 0.000
E14.8 With unspecified complications
0.857 0.143 0.000
N25-N29 Other disorders of kidney and ureter
0.855 0.145 0.000
H60 Otitis externa
0.854 0.146 0.000
Q85 Phakomatoses, not elsewhere classified
0.852 0.148 0.000
E27 Other disorders of adrenal gland
0.852 0.148 0.000
J86.0 Pyothorax with fistula
0.851 0.149 0.000
H35.2 Other proliferative retinopathy
0.850 0.150 0.000
N42 Other disorders of prostate
0.847 0.153 0.000
L10-L14 Bullous disorders
0.847 0.153 0.000
N05.2 Diffuse membranous glomerulonephritis
0.847 0.153 0.000
E83.3 Disorders of phosphorus metabolism
0.000 0.153 0.847
K82 Other diseases of gallbladder
0.846 0.154 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.846 0.154 0.000
N48.6 Balanitis xerotica obliterans
0.845 0.155 0.000
E16.1 Other hypoglycaemia
0.844 0.156 0.000
K86.2 Cyst of pancreas
0.843 0.157 0.000
E06.3 Autoimmune thyroiditis
0.842 0.158 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.840 0.160 0.000
D86.8 Sarcoidosis of other and combined sites
0.839 0.161 0.000
I20-I25 Ischaemic heart diseases
0.839 0.161 0.000
I85 Oesophageal varices
0.838 0.162 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.838 0.162 0.000
Q89 Other congenital malformations, not elsewhere classified
0.837 0.163 0.000
J86.9 Pyothorax without fistula
0.834 0.166 0.000
K74.5 Biliary cirrhosis, unspecified
0.833 0.167 0.000
E13.9 Without complications
0.832 0.168 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.831 0.169 0.000
E21.0 Primary hyperparathyroidism
0.829 0.171 0.000
I12 Hypertensive renal disease
0.826 0.174 0.000
N05.9 Unspecified
0.825 0.175 0.000
I85.9 Oesophageal varices without bleeding
0.823 0.177 0.000
I24 Other acute ischaemic heart diseases
0.823 0.177 0.000
H35.8 Other specified retinal disorders
0.822 0.178 0.000
I86 Varicose veins of other sites
0.821 0.179 0.000
E10.7 With multiple complications
0.818 0.182 0.000
Q00-Q07 Congenital malformations of the nervous system
0.816 0.184 0.000
E65-E68 Obesity and other hyperalimentation
0.816 0.184 0.000
N48.0 Leukoplakia of penis
0.815 0.185 0.000
K71 Toxic liver disease
0.814 0.186 0.000
N05.1 Focal and segmental glomerular lesions
0.812 0.188 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.810 0.190 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.809 0.191 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.806 0.194 0.000
H61.8 Other specified disorders of external ear
0.806 0.194 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.806 0.194 0.000
N48.1 Balanoposthitis
0.805 0.195 0.000
E27.1 Primary adrenocortical insufficiency
0.804 0.196 0.000
E14.6 With other specified complications
0.803 0.196 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.803 0.197 0.000
Q61.2 Polycystic kidney, adult type
0.802 0.198 0.000
E40-E46 Malnutrition
0.802 0.198 0.000
C44.2 Skin of ear and external auricular canal
0.000 0.200 0.800
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.798 0.202 0.000
H61.3 Acquired stenosis of external ear canal
0.798 0.202 0.000
E06.5 Other chronic thyroiditis
0.797 0.203 0.000
E07.9 Disorder of thyroid, unspecified
0.794 0.206 0.000
N42.9 Disorder of prostate, unspecified
0.793 0.207 0.000
K72.0 Acute and subacute hepatic failure
0.792 0.208 0.000
E11.7 With multiple complications
0.791 0.209 0.000
I86.4 Gastric varices
0.790 0.210 0.000
H80-H83 Diseases of inner ear
0.790 0.210 0.000
E24.2 Drug-induced Cushing's syndrome
0.789 0.211 0.000
N05.8 Other
0.789 0.211 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.789 0.211 0.000
K74.0 Hepatic fibrosis
0.787 0.213 0.000
H53-H54 Visual disturbances and blindness
0.786 0.214 0.000
H35.0 Background retinopathy and retinal vascular changes
0.786 0.214 0.000
D80 Immunodeficiency with predominantly antibody defects
0.785 0.215 0.000
H60.9 Otitis externa, unspecified
0.785 0.215 0.000
N18.2 Chronic kidney disease, stage 2
0.781 0.219 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.780 0.220 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.221 0.779
D86.1 Sarcoidosis of lymph nodes
0.779 0.221 0.000
Q61.3 Polycystic kidney, unspecified
0.779 0.221 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.776 0.224 0.000
Q85.9 Phakomatosis, unspecified
0.773 0.227 0.000
E14.4 With neurological complications
0.772 0.228 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.768 0.232 0.000
E24.9 Cushing's syndrome, unspecified
0.767 0.233 0.000
D82 Immunodeficiency associated with other major defects
0.767 0.233 0.000
N04.2 Diffuse membranous glomerulonephritis
0.767 0.233 0.000
Q89.2 Congenital malformations of other endocrine glands
0.766 0.234 0.000
E24.0 Pituitary-dependent Cushing's disease
0.765 0.235 0.000
K82.8 Other specified diseases of gallbladder
0.764 0.236 0.000
E14.2 Withrenal complications
0.762 0.238 0.000
H35.6 Retinal haemorrhage
0.761 0.239 0.000
C44.0 Skin of lip
0.000 0.239 0.761
E14.5 With peripheral circulatory complications
0.760 0.240 0.000
N25 Disorders resulting from impaired renal tubular function
0.760 0.240 0.000
I86.8 Varicose veins of other specified sites
0.758 0.242 0.000
L40.0 Psoriasis vulgaris
0.757 0.243 0.000
E21.3 Hyperparathyroidism, unspecified
0.757 0.243 0.000
N00 Acute nephritic syndrome
0.757 0.243 0.000
N42.2 Atrophy of prostate
0.757 0.243 0.000
K77 Liver disorders in diseases classified elsewhere
0.755 0.245 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.755 0.245 0.000
J98.4 Other disorders of lung
0.755 0.245 0.000
Q44.6 Cystic disease of liver
0.754 0.246 0.000
N18.4 Chronic kidney disease, stage 4
0.752 0.248 0.000
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.752 0.248 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.751 0.249 0.000
I15.9 Seconday hypertension, unspecified
0.751 0.249 0.000
D55-D59 Haemolytic anaemias
0.751 0.249 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.748 0.252 0.000
N04.1 Focal and segmental glomerular lesions
0.746 0.254 0.000
H43.2 Crystalline deposits in vitreous body
0.744 0.256 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.744 0.256 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.744 0.256 0.000
I85.0 Oesophageal varices with bleeding
0.743 0.257 0.000
L13 Other bullous disorders
0.743 0.257 0.000
J85 Abscess of lung and mediastinum
0.742 0.258 0.000
L40.8 Other psoriasis
0.742 0.258 0.000
I12.9 Hypertensive renal disease without renal failure
0.739 0.261 0.000
Q79.6 Ehlers-Danlos syndrome
0.739 0.261 0.000
H61.1 Non-infective disorders of pinna
0.737 0.262 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.263 0.736
J98.6 Disorders of diaphragm
0.735 0.265 0.000
H35.4 Peripheral retinal degeneration
0.732 0.268 0.000
Q83 Congenital malformations of breast
0.731 0.269 0.000
I15.1 Hypertension secondary to other renal disorders
0.730 0.269 0.000
H34.2 Other retinal artery occlusions
0.730 0.270 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.730 0.270 0.000
I70 Atherosclerosis
0.730 0.270 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.729 0.271 0.000
N27 Small kidney of unknown cause
0.728 0.272 0.000
I11 Hypertensive heart disease
0.727 0.273 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.275 0.725
N08.1 Glomerular disorders in neoplastic diseases
0.725 0.275 0.000
G36 Other acute disseminated demyelination
0.001 0.276 0.723
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.276 0.723
H54 Blindness and low vision
0.721 0.279 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.719 0.281 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.718 0.282 0.000
E14.7 With multiple complications
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.717 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.717 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.717 0.283 0.000
E16.3 Increased secretion of glucagon
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
K90.3 Pancreatic steatorrhoea
0.717 0.283 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.717 0.283 0.000
K90.1 Tropical sprue
0.717 0.283 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.716 0.283 0.000
E05.5 Thyroid crisis or storm
0.716 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.716 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.716 0.283 0.000
H80 Otosclerosis
0.716 0.284 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.716 0.284 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.716 0.284 0.000
H43.0 Vitreous prolapse
0.716 0.284 0.000
C44.8 Overlapping lesion of skin
0.000 0.284 0.715
L40.1 Generalised pustular psoriasis
0.715 0.284 0.000
H34.9 Retinal vascular occlusion, unspecified
0.715 0.285 0.000
J45.1 Nonallergic asthma
0.714 0.286 0.000
J42 Unspecified chronic bronchitis
0.714 0.286 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.713 0.287 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.713 0.287 0.000
C44.4 Skin of scalp and neck
0.000 0.287 0.713
K82.9 Disease of gallbladder, unspecified
0.713 0.287 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.712 0.288 0.000
E14.0 With coma
0.711 0.288 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.711 0.289 0.000
Q85.0 Neurofibromatosis (nonmalignant)
0.711 0.289 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.710 0.290 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.710 0.290 0.000
E66 Obesity
0.710 0.290 0.000
G37.5 Concentric sclerosis [Balo]
0.000 0.291 0.709
G37.4 Subacute necrotising myelitis
0.000 0.291 0.709
G37.2 Central pontine myelinolysis
0.000 0.291 0.709
G37.1 Central demyelination of corpus callosum
0.000 0.291 0.709
G37.0 Diffuse sclerosis
0.000 0.291 0.709
J95.0 Tracheostomy malfunction
0.708 0.292 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.708 0.292 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.708 0.292 0.000
D64.4 Congenital dyserythropoietic anaemia
0.708 0.292 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.708 0.292 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.708 0.292 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.707 0.293 0.000
J33.1 Polypoid sinus degeneration
0.706 0.294 0.000
N04.8 Other
0.706 0.294 0.000
E06.1 Subacute thyroiditis
0.706 0.294 0.000
J98.9 Respiratory disorder, unspecified
0.706 0.294 0.000
K74.4 Secondary biliary cirrhosis
0.704 0.296 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.704 0.296 0.000
K74.1 Hepatic sclerosis
0.704 0.296 0.000
L44 Other papulosquamous disorders
0.704 0.296 0.000
C44.6 Skin of upper limb, including shoulder
0.000 0.296 0.704
K75.2 Nonspecific reactive hepatitis
0.703 0.297 0.000
K75.1 Phlebitis of portal vein
0.703 0.297 0.000
Q38.7 Pharyngeal pouch
0.703 0.297 0.000
Q78 Other osteochondrodysplasias
0.701 0.299 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.699 0.301 0.000
N06 Isolated proteinuria with specified morphological lesion
0.699 0.301 0.000
N01 Rapidly progressive nephritic syndrome
0.699 0.301 0.000
D83 Common variable immunodeficiency
0.699 0.301 0.000
D81 Combined immunodeficiencies
0.698 0.302 0.000
J45.0 Predominantly allergic asthma
0.698 0.302 0.000
H35.5 Hereditary retinal dystrophy
0.697 0.303 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.695 0.305 0.000
H54.7 Unspecified visual loss
0.694 0.306 0.000
J98.8 Other specified respiratory disorders
0.694 0.306 0.000
N42.1 Congestion and haemorrhage of prostate
0.694 0.306 0.000
L90.9 Atrophic disorder of skin, unspecified
0.692 0.307 0.000
E31 Polyglandular dysfunction
0.692 0.308 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.691 0.309 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.691 0.309 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.691 0.309 0.000
Q61.0 Congenital single renal cyst
0.690 0.310 0.000
L10 Pemphigus
0.689 0.310 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.689 0.310 0.000
L87 Transepidermal elimination disorders
0.689 0.311 0.000
L86 Keratoderma in diseases classified elsewhere
0.689 0.311 0.000
I15.2 Hypertension secondary to endocrine disorders
0.688 0.312 0.000
L90.6 Striae atrophicae
0.686 0.314 0.000
L90.4 Acrodermatitis chronica atrophicans
0.686 0.314 0.000
L90.3 Atrophoderma of Pasini and Pierini
0.686 0.314 0.000
L90.2 Anetoderma of Jadassohn-Pellizzari
0.686 0.314 0.000
L90.1 Anetoderma of Schweninger-Buzzi
0.686 0.314 0.000
N05.6 Dense deposit disease
0.686 0.314 0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.686 0.314 0.000
N05.0 Minor glomerular abnormality
0.686 0.314 0.000
J37 Chronic laryngitis and laryngotracheitis
0.686 0.314 0.000
Q38.1 Ankyloglossia
0.686 0.314 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.685 0.315 0.000
H60.3 Other infective otitis externa
0.685 0.315 0.000
K72.9 Hepatic failure, unspecified
0.685 0.315 0.000
L40.3 Pustulosis palmaris et plantaris
0.685 0.315 0.000
E66.9 Obesity, unspecified
0.684 0.316 0.000
D50.1 Sideropenic dysphagia
0.683 0.317 0.000
H34.0 Transient retinal artery occlusion
0.683 0.317 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.682 0.318 0.000
E30 Disorders of puberty, not elsewhere classified
0.682 0.318 0.000
E20 Hypoparathyroidism
0.682 0.318 0.000
J45.8 Mixed asthma
0.680 0.320 0.000
N04.0 Minor glomerular abnormality
0.680 0.320 0.000
K73.9 Chronic hepatitis, unspecified
0.680 0.320 0.000
I70.0 Atherosclerosis of aorta
0.680 0.320 0.000
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.679 0.321 0.000
Q35-Q37 Cleft lip and cleft palate
0.677 0.323 0.000
I00-I02 Acute rheumatic fever
0.677 0.323 0.000
J43.1 Panlobular emphysema
0.675 0.325 0.000
J43.0 MacLeod's syndrome
0.675 0.325 0.000
E32 Diseases of thymus
0.674 0.326 0.000
N18.0 End-stage renal disease
0.673 0.327 0.000
L94 Other localised connective tissue disorders
0.673 0.327 0.000
Q04 Other congenital malformations of brain
0.673 0.327 0.000
N05.7 Diffuse crescentic glomerulonephritis
0.672 0.328 0.000
E05.8 Other thyrotoxicosis
0.671 0.329 0.000
J43.2 Centrilobular emphysema
0.671 0.329 0.000
I86.2 Pelvic varices
0.671 0.329 0.000
E06.4 Drug-induced thyroiditis
0.671 0.329 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.671 0.329 0.000
E06.0 Acute thyroiditis
0.671 0.329 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.670 0.330 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.670 0.330 0.000
N04.6 Dense deposit disease
0.670 0.330 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.670 0.330 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.670 0.330 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.670 0.330 0.000
I15.0 Renovascular hypertension
0.669 0.331 0.000
K71.0 Toxic liver disease with cholestasis
0.669 0.331 0.000
Q38.6 Other congenital malformations of mouth
0.669 0.331 0.000
Q80 Congenital ichthyosis
0.668 0.331 0.000
E24.8 Other Cushing's syndrome
0.668 0.332 0.000
L13.0 Dermatitis herpetiformis
0.667 0.333 0.000
J96 Respiratory failure, not elsewhere classified
0.666 0.334 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.665 0.335 0.000
Q84 Other congenital malformations of integument
0.665 0.335 0.000
Q81 Epidermolysis bullosa
0.665 0.335 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.664 0.336 0.000
N18.8 Other chronic renal failure
0.662 0.338 0.000
H35.1 Retinopathy of prematurity
0.662 0.338 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.661 0.339 0.000
Q44.5 Other congenital malformations of bile ducts
0.660 0.339 0.000
H34.1 Central retinal artery occlusion
0.660 0.340 0.000
E46 Unspecified protein-energy malnutrition
0.660 0.340 0.000
L41 Parapsoriasis
0.659 0.341 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.659 0.341 0.000
H30 Chorioretinal inflammation
0.657 0.343 0.000
K82.3 Fistula of gallbladder
0.657 0.343 0.000
Q45 Other congenital malformations of digestive system
0.657 0.343 0.000
E03.1 Congenital hypothyroidism without goitre
0.655 0.344 0.000
D58 Other hereditary haemolytic anaemias
0.656 0.344 0.000
J98.2 Interstitial emphysema
0.655 0.344 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.655 0.345 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.655 0.345 0.000
D53 Other nutritional anaemias
0.654 0.345 0.000
Q68 Other congenital musculoskeletal deformities
0.652 0.348 0.000
N48.4 Impotence of organic origin
0.652 0.348 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.651 0.349 0.000
E11.8 With unspecified complications
0.651 0.349 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.651 0.349 0.000
Q70 Syndactyly
0.650 0.350 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.650 0.350 0.000
E24.3 Ectopic ACTH syndrome
0.650 0.350 0.000
E24.1 Nelson's syndrome
0.650 0.350 0.000
L40.2 Acrodermatitis continua
0.650 0.350 0.000
J41 Simple and mucopurulent chronic bronchitis
0.648 0.352 0.000
H43.9 Disorder of vitreous body, unspecified
0.648 0.352 0.000
N48.9 Disorder of penis, unspecified
0.647 0.353 0.000
E06.9 Thyroiditis, unspecified
0.646 0.354 0.000
K75.8 Other specified inflammatory liver diseases
0.646 0.354 0.000
H60.2 Malignant otitis externa
0.645 0.355 0.000
E13.8 With unspecified complications
0.645 0.355 0.000
E13.7 With multiple complications
0.645 0.355 0.000
E13.6 With other specified complications
0.645 0.355 0.000
E13.5 With peripheral circulatory complications
0.645 0.355 0.000
E13.4 With neurological complications
0.645 0.355 0.000
E13.2 With renal complications
0.645 0.355 0.000
E13.1 With ketoacidosis
0.645 0.355 0.000
E13.0 With coma
0.645 0.355 0.000
I70.00 Atherosclerosis of aorta (without gangrene)
0.644 0.356 0.000
J85.2 Abscess of lung without pneumonia
0.644 0.356 0.000
N18.1 Chronic kidney disease, stage 1
0.642 0.358 0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.642 0.358 0.000
N49.2 Inflammatory disorders of scrotum
0.641 0.359 0.000
N27.1 Small kidney, bilateral
0.637 0.363 0.000
K90.8 Other intestinal malabsorption
0.637 0.363 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.637 0.363 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.637 0.363 0.000
E29 Testicular dysfunction
0.637 0.363 0.000
I73 Other peripheral vascular diseases
0.636 0.364 0.000
L40.4 Guttate psoriasis
0.636 0.364 0.000
E07.8 Other specified disorders of thyroid
0.633 0.366 0.000
Q76 Congenital malformations of spine and bony thorax
0.633 0.367 0.000
E28 Ovarian dysfunction
0.633 0.367 0.000
K72.1 Chronic hepatic failure
0.632 0.368 0.000
H60.5 Acute otitis externa, non-infective
0.632 0.368 0.000
I15.8 Other secondary hypertension
0.632 0.368 0.000
Q38.8 Other congenital malformations of pharynx
0.631 0.369 0.000
E07.1 Dyshormogenetic goitre
0.631 0.369 0.000
E07.0 Hypersecretion of calcitonin
0.631 0.369 0.000
Q39 Congenital malformations of oesophagus
0.631 0.369 0.000
I74 Arterial embolism and thrombosis
0.631 0.369 0.000
Q75 Other congenital malformations of skull and face bones
0.631 0.369 0.000
E13.3 With ophthalmic complications
0.630 0.369 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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