TreeWAS – Variant ID: rs384247

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
G35 Multiple sclerosis	0.000	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	0.999	0.001	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.001	0.999
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.001	0.999
E10 Insulin-dependent diabetes mellitus	0.000	0.002	0.998
E05.9 Thyrotoxicosis, unspecified	0.000	0.002	0.998
E10-E14 Diabetes mellitus	0.000	0.002	0.998
E00-E07 Disorders of thyroid gland	0.000	0.003	0.997
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.995	0.005	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.009	0.991
E27 Other disorders of adrenal gland	0.000	0.010	0.990
M06 Other rheumatoid arthritis	0.990	0.010	0.000
E10.9 Without complications	0.000	0.013	0.987
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.982	0.018	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.018	0.982
L40.5 Arthropathic psoriasis	0.000	0.018	0.982
L40 Psoriasis	0.000	0.021	0.979
L40.9 Psoriasis, unspecified	0.000	0.023	0.977
E10.3 With ophthalmic complications	0.000	0.029	0.971
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.030	0.970
M05.9 Seropositive rheumatoid arthritis, unspecified	0.970	0.030	0.000
M05 Seropositive rheumatoid arthritis	0.967	0.033	0.000
M05-M14 Inflammatory polyarthropathies	0.964	0.035	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.956	0.044	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.955	0.045	0.000
E50-E64 Other nutritional deficiencies	0.000	0.057	0.943
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.940	0.060	0.000
E10.2 With renal complications	0.000	0.061	0.939
M06.3 Rheumatoid nodule	0.913	0.087	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.913	0.087	0.000
E55 Vitamin D deficiency	0.000	0.091	0.909
E55.9 Vitamin D deficiency, unspecified	0.000	0.115	0.885
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.871	0.129	0.000
K90 Intestinal malabsorption	0.000	0.130	0.870
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.132	0.868
M06.98 Rheumatoid arthritis, unspecified (Other)	0.868	0.132	0.000
E27.2 Addisonian crisis	0.000	0.137	0.863
M06.34 Rheumatoid nodule (Hand)	0.841	0.159	0.000
E20 Hypoparathyroidism	0.000	0.162	0.838
E10.1 With ketoacidosis	0.000	0.177	0.823
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.818	0.182	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.810	0.190	0.000
E10.6 With other specified complications	0.000	0.195	0.805
K90.9 Intestinal malabsorption, unspecified	0.000	0.204	0.796
M06.0 Seronegative rheumatoid arthritis	0.792	0.208	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.209	0.791
E05.8 Other thyrotoxicosis	0.000	0.210	0.790
E10.5 With peripheral circulatory complications	0.000	0.217	0.782
E13 Other specified diabetes mellitus	0.000	0.220	0.780
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.220	0.780
L40.0 Psoriasis vulgaris	0.000	0.226	0.774
M05.1 Rheumatoid lung disease	0.765	0.235	0.000
L40-L45 Papulosquamous disorders	0.000	0.235	0.765
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.763	0.237	0.000
E10.0 With coma	0.000	0.243	0.757
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.251	0.748
E10.4 With neurological complications	0.000	0.255	0.745
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.744	0.256	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.742	0.258	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.742	0.258	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.265	0.734
E27.8 Other specified disorders of adrenal gland	0.000	0.268	0.732
E20.9 Hypoparathyroidism, unspecified	0.000	0.271	0.729
E65-E68 Obesity and other hyperalimentation	0.000	0.271	0.729
M06.32 Rheumatoid nodule (Upper arm)	0.718	0.282	0.000
E05.5 Thyroid crisis or storm	0.000	0.284	0.716
E05.4 Thyrotoxicosis factitia	0.000	0.284	0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.284	0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.284	0.716
E10.7 With multiple complications	0.000	0.284	0.716
E12 Malnutrition-related diabetes mellitus	0.000	0.285	0.715
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.285	0.715
E00 Congenital iodine-deficiency syndrome	0.000	0.285	0.715
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.285	0.715
M12 Other specific arthropathies	0.714	0.286	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.000	0.289	0.711
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.289	0.711
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.289	0.711
E32 Diseases of thymus	0.000	0.289	0.711
E31 Polyglandular dysfunction	0.000	0.289	0.711
E30 Disorders of puberty, not elsewhere classified	0.000	0.289	0.711
E27.5 Adrenomedullary hyperfunction	0.000	0.290	0.710
E27.0 Other adrenocortical overactivity	0.000	0.290	0.710
M06.8 Other specified rheumatoid arthritis	0.710	0.290	0.000
M06.2 Rheumatoid bursitis	0.710	0.290	0.000
M06.1 Adult-onset Still's disease	0.710	0.290	0.000
M05.8 Other seropositive rheumatoid arthritis	0.707	0.293	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.296	0.703
L40.4 Guttate psoriasis	0.000	0.298	0.702
L40.3 Pustulosis palmaris et plantaris	0.000	0.298	0.702
L40.2 Acrodermatitis continua	0.000	0.298	0.702
L40.1 Generalised pustular psoriasis	0.000	0.298	0.702
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.695	0.305	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.695	0.305	0.000
E53 Deficiency of other B group vitamins	0.000	0.305	0.695
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.000	0.305	0.695
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.693	0.306	0.000
M05.2 Rheumatoid vasculitis	0.693	0.306	0.000
M05.0 Felty's syndrome	0.693	0.306	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.691	0.308	0.000
M08 Juvenile arthritis	0.691	0.308	0.000
E25 Adrenogenital disorders	0.000	0.309	0.691
E24 Cushing's syndrome	0.000	0.309	0.691
L40.8 Other psoriasis	0.000	0.313	0.687
M11 Other crystal arthropathies	0.687	0.313	0.000
L08 Other local infections of skin and subcutaneous tissue	0.000	0.314	0.686
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.682	0.318	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.000	0.318	0.682
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.324	0.676
E63 Other nutritional deficiencies	0.000	0.324	0.676
E56 Other vitamin deficiencies	0.000	0.324	0.676
E51 Thiamine deficiency	0.000	0.324	0.676
E50 Vitamin A deficiency	0.000	0.324	0.676
E60 Dietary zinc deficiency	0.000	0.324	0.676
E59 Dietary selenium deficiency	0.000	0.324	0.676
E58 Dietary calcium deficiency	0.000	0.324	0.676
E54 Ascorbic acid deficiency	0.000	0.324	0.676
E52 Niacin deficiency [pellagra]	0.000	0.324	0.676
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.676	0.324	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.670	0.330	0.000
E06 Thyroiditis	0.000	0.331	0.668
E26 Hyperaldosteronism	0.000	0.333	0.667
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.334	0.666
E22 Hyperfunction of pituitary gland	0.000	0.335	0.665
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.659	0.341	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.655	0.345	0.000
M06.38 Rheumatoid nodule (Other)	0.655	0.345	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.655	0.345	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.655	0.345	0.000
M06.33 Rheumatoid nodule (Forearm)	0.655	0.345	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.655	0.345	0.000
E55.0 Rickets, active	0.000	0.348	0.652
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.651	0.349	0.000
E29 Testicular dysfunction	0.000	0.350	0.650
K90.8 Other intestinal malabsorption	0.000	0.351	0.649
G37 Other demyelinating diseases of central nervous system	0.000	0.356	0.644
L71.9 Rosacea, unspecified	0.000	0.358	0.642
L60-L75 Disorders of skin appendages	0.000	0.360	0.640
L71 Rosacea	0.000	0.360	0.640
M06.37 Rheumatoid nodule (Ankle and foot)	0.635	0.365	0.000
E13.9 Without complications	0.000	0.376	0.624
K90.3 Pancreatic steatorrhoea	0.000	0.376	0.624
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.376	0.624
K90.1 Tropical sprue	0.000	0.376	0.624
M05.19 Rheumatoid lung disease (Site unspecified)	0.621	0.379	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.384	0.616
E28 Ovarian dysfunction	0.000	0.390	0.610
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.391	0.609
M06.4 Inflammatory polyarthropathy	0.607	0.393	0.000
E61 Deficiency of other nutrient elements	0.000	0.395	0.605
M14 Arthropathies in other diseases classified elsewhere	0.602	0.398	0.000
# Top node	0.000	0.398	0.602
E20.8 Other hypoparathyroidism	0.000	0.399	0.601
E20.1 Pseudohypoparathyroidism	0.000	0.399	0.601
E20.0 Idiopathic hypoparathyroidism	0.000	0.399	0.601
Chapter VI Diseases of the nervous system	0.000	0.405	0.595
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.409	0.591
D80-D89 Certain disorders involving the immune mechanism	0.000	0.410	0.590
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.589	0.411	0.000
E23.6 Other disorders of pituitary gland	0.000	0.416	0.584
Chapter I Certain infectious and parasitic diseases	0.000	0.416	0.584
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.581	0.419	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.420	0.580
E10.8 With unspecified complications	0.000	0.420	0.580
E40-E46 Malnutrition	0.000	0.423	0.576
D86 Sarcoidosis	0.000	0.430	0.570
M06.08 Seronegative rheumatoid arthritis (Other)	0.568	0.432	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.568	0.432	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.568	0.432	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.568	0.432	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.568	0.432	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.568	0.432	0.000
D75 Other diseases of blood and blood-forming organs	0.000	0.435	0.565
E23.7 Disorder of pituitary gland, unspecified	0.000	0.437	0.563
L10-L14 Bullous disorders	0.000	0.437	0.563
E13.8 With unspecified complications	0.000	0.440	0.559
E13.7 With multiple complications	0.000	0.440	0.559
E13.6 With other specified complications	0.000	0.440	0.559
E13.5 With peripheral circulatory complications	0.000	0.440	0.559
E13.4 With neurological complications	0.000	0.440	0.559
E13.3 With ophthalmic complications	0.000	0.440	0.559
E13.2 With renal complications	0.000	0.440	0.559
E13.1 With ketoacidosis	0.000	0.440	0.559
E13.0 With coma	0.000	0.440	0.559
A50-A64 Infections with a predominantly sexual mode of transmission	0.000	0.440	0.560
E65 Localised adiposity	0.000	0.450	0.550
M05.18 Rheumatoid lung disease (Other)	0.549	0.451	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.549	0.451	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.549	0.451	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.549	0.451	0.000
M05.14 Rheumatoid lung disease (Hand)	0.549	0.451	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.549	0.451	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.549	0.451	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.549	0.451	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.549	0.451	0.000
L44 Other papulosquamous disorders	0.000	0.451	0.549
L41 Parapsoriasis	0.000	0.451	0.549
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.451	0.549
M10 Gout	0.548	0.452	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.000	0.457	0.543
M12.3 Palindromic rheumatism	0.542	0.458	0.000
E34 Other endocrine disorders	0.000	0.460	0.540
A63.0 Anogenital (venereal) warts	0.000	0.468	0.532
G36 Other acute disseminated demyelination	0.000	0.470	0.529
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.529	0.471	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.471	0.529
E24.2 Drug-induced Cushing's syndrome	0.000	0.472	0.528
D72 Other disorders of white blood cells	0.000	0.472	0.528
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.528	0.472	0.000
E53.8 Deficiency of other specified B group vitamins	0.000	0.472	0.528
D69 Purpura and other haemorrhagic conditions	0.000	0.476	0.524
E67 Other hyperalimentation	0.000	0.477	0.522
E68 Sequelae of hyperalimentation	0.000	0.477	0.522
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.520	0.480	0.000
D55-D59 Haemolytic anaemias	0.000	0.480	0.520
D75.1 Secondary polycythaemia	0.000	0.481	0.519
B25-B34 Other viral diseases	0.000	0.481	0.519
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.484	0.516
D86.0 Sarcoidosis of lung	0.000	0.485	0.514
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.000	0.487	0.513
E12.9 Without complications	0.000	0.487	0.513
E12.8 With unspecified complications	0.000	0.487	0.513
E12.7 With multiple complications	0.000	0.487	0.513
E12.6 With other specified complications	0.000	0.487	0.513
E12.5 With peripheral circulatory complications	0.000	0.487	0.513
E12.4 With neurological complications	0.000	0.487	0.513
E12.3 With ophthalmic complications	0.000	0.487	0.513
E12.2 With renal complications	0.000	0.487	0.513
E12.1 With ketoacidosis	0.000	0.487	0.513
E12.0 With coma	0.000	0.487	0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.487	0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.487	0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.487	0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.487	0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.487	0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.487	0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.487	0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.487	0.513
M12.8 Other specific arthropathies, not elsewhere classified	0.512	0.488	0.000
M12.5 Traumatic arthropathy	0.512	0.488	0.000
M12.4 Intermittent hydrarthrosis	0.512	0.488	0.000
M12.1 Kaschin-Beck disease	0.512	0.488	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.512	0.488	0.000
E15 Nondiabetic hypoglycaemic coma	0.000	0.490	0.510
E30.9 Disorder of puberty, unspecified	0.000	0.490	0.510
E30.8 Other disorders of puberty	0.000	0.490	0.510
E30.1 Precocious puberty	0.000	0.490	0.510
E30.0 Delayed puberty	0.000	0.490	0.510
E31.9 Polyglandular dysfunction, unspecified	0.000	0.490	0.510
E31.8 Other polyglandular dysfunction	0.000	0.490	0.510
E31.1 Polyglandular hyperfunction	0.000	0.490	0.510
E31.0 Autoimmune polyglandular failure	0.000	0.490	0.510
E32.9 Disease of thymus, unspecified	0.000	0.490	0.510
E32.8 Other diseases of thymus	0.000	0.490	0.510
E32.1 Abscess of thymus	0.000	0.490	0.510
E32.0 Persistent hyperplasia of thymus	0.000	0.490	0.510
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.490	0.510
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.490	0.510
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.490	0.510
M06.19 Adult-onset Still's disease (Site unspecified)	0.509	0.491	0.000
M06.18 Adult-onset Still's disease (Other)	0.509	0.491	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.509	0.491	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.509	0.491	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.509	0.491	0.000
M06.14 Adult-onset Still's disease (Hand)	0.509	0.491	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.509	0.491	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.509	0.491	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.509	0.491	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.509	0.491	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.509	0.491	0.000
M06.28 Rheumatoid bursitis (Other)	0.509	0.491	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.509	0.491	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.509	0.491	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.509	0.491	0.000
M06.24 Rheumatoid bursitis (Hand)	0.509	0.491	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.509	0.491	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.509	0.491	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.509	0.491	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.509	0.491	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.509	0.491	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.509	0.491	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.509	0.491	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.509	0.491	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.509	0.491	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.509	0.491	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.509	0.491	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.509	0.491	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.509	0.491	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.509	0.491	0.000
E06.9 Thyroiditis, unspecified	0.000	0.492	0.508
D73 Diseases of spleen	0.000	0.492	0.508
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.507	0.493	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.507	0.493	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.507	0.493	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.507	0.493	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.507	0.493	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.507	0.493	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.507	0.493	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.507	0.493	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.507	0.493	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.494	0.506
E21.0 Primary hyperparathyroidism	0.000	0.494	0.506
E16 Other disorders of pancreatic internal secretion	0.000	0.495	0.505
L08.8 Other specified local infections of skin and subcutaneous tissue	0.000	0.495	0.505
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.495	0.505
E66 Obesity	0.000	0.495	0.505
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.495	0.504
E23.1 Drug-induced hypopituitarism	0.000	0.495	0.504
M12.2 Villonodular synovitis (pigmented)	0.503	0.496	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.497	0.503
B15-B19 Viral hepatitis	0.000	0.497	0.503
E53.1 Pyridoxine deficiency	0.000	0.501	0.498
E53.0 Riboflavin deficiency	0.000	0.501	0.498
E07 Other disorders of thyroid	0.000	0.502	0.498
M05.09 Felty's syndrome (Site unspecified)	0.497	0.503	0.000
M05.08 Felty's syndrome (Other)	0.497	0.503	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.497	0.503	0.000
M05.06 Felty's syndrome (Lower leg)	0.497	0.503	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.497	0.503	0.000
M05.04 Felty's syndrome (Hand)	0.497	0.503	0.000
M05.03 Felty's syndrome (Forearm)	0.497	0.503	0.000
M05.02 Felty's syndrome (Upper arm)	0.497	0.503	0.000
M05.01 Felty's syndrome (Shoulder region)	0.497	0.503	0.000
M05.00 Felty's syndrome (Multiple sites)	0.497	0.503	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.497	0.503	0.000
M05.28 Rheumatoid vasculitis (Other)	0.497	0.503	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.497	0.503	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.497	0.503	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.497	0.503	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.497	0.503	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.497	0.503	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.497	0.503	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.497	0.503	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.497	0.503	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.497	0.503	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.497	0.503	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.497	0.503	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.497	0.503	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.497	0.503	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.497	0.503	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.497	0.503	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.497	0.503	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.497	0.503	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.497	0.503	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.503	0.497
M08.9 Juvenile arthritis, unspecified	0.496	0.504	0.000
M08.8 Other juvenile arthritis	0.496	0.504	0.000
M08.4 Pauciarticular juvenile arthritis	0.496	0.504	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.496	0.504	0.000
M08.2 Juvenile arthritis with systemic onset	0.496	0.504	0.000
M08.1 Juvenile ankylosing spondylitis	0.496	0.504	0.000
M08.0 Juvenile rheumatoid arthritis	0.496	0.504	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.496	0.504	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.496	0.504	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.496	0.504	0.000
M09.0 Juvenile arthritis in psoriasis	0.496	0.504	0.000
E25.9 Adrenogenital disorder, unspecified	0.000	0.504	0.495
E25.8 Other adrenogenital disorders	0.000	0.504	0.495
E24.8 Other Cushing's syndrome	0.000	0.504	0.495
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.504	0.495
E24.3 Ectopic ACTH syndrome	0.000	0.504	0.495
E24.1 Nelson's syndrome	0.000	0.504	0.495
E24.0 Pituitary-dependent Cushing's disease	0.000	0.504	0.495
B35-B49 Mycoses	0.000	0.505	0.495
D72.8 Other specified disorders of white blood cells	0.000	0.507	0.493
M11.9 Crystal arthropathy, unspecified	0.492	0.508	0.000
M11.8 Other specified crystal arthropathies	0.492	0.508	0.000
M11.1 Familial chondrocalcinosis	0.492	0.508	0.000
M11.0 Hydroxyapatite deposition disease	0.492	0.508	0.000
L08.1 Erythrasma	0.000	0.508	0.492
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.508	0.492
L01 Impetigo	0.000	0.511	0.489
L00 Staphylococcal scalded skin syndrome	0.000	0.511	0.489
M11.2 Other chondrocalcinosis	0.487	0.512	0.000
E53.9 Vitamin B deficiency, unspecified	0.000	0.514	0.486
B18 Chronic viral hepatitis	0.000	0.514	0.485
L04 Acute lymphadenitis	0.000	0.515	0.485
E50.9 Vitamin A deficiency, unspecified	0.000	0.515	0.485
E50.8 Other manifestations of vitamin A deficiency	0.000	0.515	0.485
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.515	0.485
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.515	0.485
E50.5 Vitamin A deficiency with night blindness	0.000	0.515	0.485
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.515	0.485
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.515	0.485
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.515	0.485
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.515	0.485
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.515	0.485
E51.9 Thiamine deficiency, unspecified	0.000	0.515	0.485
E51.8 Other manifestations of thiamine deficiency	0.000	0.515	0.485
E51.2 Wernicke's encephalopathy	0.000	0.515	0.485
E51.1 Beriberi	0.000	0.515	0.485
E56.9 Vitamin deficiency, unspecified	0.000	0.515	0.485
E56.8 Deficiency of other vitamins	0.000	0.515	0.485
E56.1 Deficiency of vitamin K	0.000	0.515	0.485
E56.0 Deficiency of vitamin E	0.000	0.515	0.485
E63.9 Nutritional deficiency, unspecified	0.000	0.515	0.485
E63.8 Other specified nutritional deficiencies	0.000	0.515	0.485
E63.1 Imbalance of constituents of food intake	0.000	0.515	0.485
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.515	0.485
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.515	0.485
E64.8 Sequelae of other nutritional deficiencies	0.000	0.515	0.485
E64.3 Sequelae of rickets	0.000	0.515	0.485
E64.2 Sequelae of vitamin C deficiency	0.000	0.515	0.485
E64.1 Sequelae of vitamin A deficiency	0.000	0.515	0.485
E64.0 Sequelae of protein-energy malnutrition	0.000	0.515	0.485
E06.5 Other chronic thyroiditis	0.000	0.521	0.479
E06.4 Drug-induced thyroiditis	0.000	0.521	0.479
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.521	0.479
E06.1 Subacute thyroiditis	0.000	0.521	0.479
E06.0 Acute thyroiditis	0.000	0.521	0.479
Chapter XXII Codes for special purposes	0.000	0.521	0.479
E22.1 Hyperprolactinaemia	0.000	0.521	0.478
E26.9 Hyperaldosteronism, unspecified	0.000	0.522	0.478
E26.8 Other hyperaldosteronism	0.000	0.522	0.478
E26.1 Secondary hyperaldosteronism	0.000	0.522	0.478
D68 Other coagulation defects	0.000	0.522	0.478
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.523	0.476
E22.8 Other hyperfunction of pituitary gland	0.000	0.523	0.476
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.524	0.476
M07 Psoriatic and enteropathic arthropathies	0.465	0.524	0.011
B37 Candidiasis	0.000	0.526	0.474
E14 Unspecified diabetes mellitus	0.000	0.526	0.474
E61.2 Magnesium deficiency	0.000	0.532	0.468
B37.8 Candidiasis of other sites	0.000	0.533	0.467
E29.9 Testicular dysfunction, unspecified	0.000	0.534	0.466
E29.8 Other testicular dysfunction	0.000	0.534	0.466
E29.0 Testicular hyperfunction	0.000	0.534	0.466
L70 Acne	0.000	0.534	0.465
L66 Cicatricial alopecia [scarring hair loss]	0.000	0.535	0.464
D66 Hereditary factor VIII deficiency	0.000	0.536	0.464
G37.5 Concentric sclerosis [Balo]	0.000	0.538	0.462
G37.4 Subacute necrotising myelitis	0.000	0.538	0.462
G37.2 Central pontine myelinolysis	0.000	0.538	0.462
G37.1 Central demyelination of corpus callosum	0.000	0.538	0.462
G37.0 Diffuse sclerosis	0.000	0.538	0.462
L71.1 Rhinophyma	0.000	0.539	0.461
L50-L54 Urticaria and erythema	0.000	0.540	0.460
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.000	0.540	0.460
B18.2 Chronic viral hepatitis C	0.000	0.540	0.460
L75 Apocrine sweat disorders	0.000	0.541	0.459
L74 Eccrine sweat disorders	0.000	0.541	0.459
L67 Hair colour and hair shaft abnormalities	0.000	0.541	0.459
L64 Androgenic alopecia	0.000	0.541	0.459
L63 Alopecia areata	0.000	0.541	0.459
L62 Nail disorders in diseases classified elsewhere	0.000	0.541	0.459
L71.8 Other rosacea	0.000	0.541	0.459
L71.0 Perioral dermatitis	0.000	0.541	0.459
E03 Other hypothyroidism	0.000	0.542	0.458
E28.3 Primary ovarian failure	0.000	0.543	0.457
K90-K93 Other diseases of the digestive system	0.000	0.544	0.456
B34 Viral infection of unspecified site	0.000	0.545	0.455
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.546	0.454
B99-B99 Other infectious diseases	0.000	0.548	0.452
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.551	0.449
L11 Other acantholytic disorders	0.000	0.552	0.448
D86.1 Sarcoidosis of lymph nodes	0.000	0.554	0.446
D73.0 Hyposplenism	0.000	0.555	0.445
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.556	0.444
G80-G83 Cerebral palsy and other paralytic syndromes	0.000	0.557	0.443
E21.2 Other hyperparathyroidism	0.000	0.558	0.442
B20-B24 Human immunodeficiency virus [HIV] disease	0.000	0.558	0.442
D69.9 Haemorrhagic condition, unspecified	0.000	0.561	0.439
D59 Acquired haemolytic anaemia	0.000	0.562	0.438
G70-G73 Diseases of myoneural junction and muscle	0.000	0.562	0.438
E28.9 Ovarian dysfunction, unspecified	0.000	0.562	0.438
E28.8 Other ovarian dysfunction	0.000	0.562	0.438
E28.1 Androgen excess	0.000	0.562	0.438
E28.0 Oestrogen excess	0.000	0.562	0.438
E21.3 Hyperparathyroidism, unspecified	0.000	0.563	0.437
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.563	0.437
M06.48 Inflammatory polyarthropathy (Other)	0.435	0.564	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.435	0.564	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.435	0.564	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.435	0.564	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.435	0.564	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.435	0.564	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.435	0.564	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.435	0.564	0.000
B07 Viral warts	0.000	0.565	0.435
E26.0 Primary hyperaldosteronism	0.000	0.565	0.434
E61.9 Deficiency of nutrient element, unspecified	0.000	0.566	0.434
E61.8 Deficiency of other specified nutrient elements	0.000	0.566	0.434
E61.7 Deficiency of multiple nutrient elements	0.000	0.566	0.434
E61.6 Vanadium deficiency	0.000	0.566	0.434
E61.5 Molybdenum deficiency	0.000	0.566	0.434
E61.4 Chromium deficiency	0.000	0.566	0.434
E61.3 Manganese deficiency	0.000	0.566	0.434
E61.0 Copper deficiency	0.000	0.566	0.434
L65 Other nonscarring hair loss	0.000	0.568	0.432
E24.9 Cushing's syndrome, unspecified	0.000	0.568	0.432
M14.8 Arthropathies in other specified diseases classified elsewhere	0.431	0.568	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.431	0.568	0.000
M14.4 Arthropathy in amyloidosis	0.431	0.568	0.000
M14.3 Lipoid dermatoarthritis	0.431	0.568	0.000
M14.2 Diabetic arthropathy	0.431	0.568	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.431	0.568	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.431	0.568	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.000	0.569	0.431
D86.8 Sarcoidosis of other and combined sites	0.000	0.569	0.431

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations