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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3873375
log Bayes Factor = 44.6381
Chromosome 6   position 31,251,360  (GRCh37) Explore rs3873375 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.007 0.993
M45 Ankylosing spondylitis
0.000 0.038 0.962
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.060 0.940
L40.0 Psoriasis vulgaris
0.000 0.061 0.939
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.121 0.879
L40.8 Other psoriasis
0.000 0.199 0.800
L40.3 Pustulosis palmaris et plantaris
0.000 0.244 0.756
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.265 0.735
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
M07.3 Other psoriatic arthropathies
0.000 0.285 0.715
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.294 0.706
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.310 0.689
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.310 0.689
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.310 0.689
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.310 0.689
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.310 0.689
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.310 0.689
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.310 0.689
E03 Other hypothyroidism
0.000 0.352 0.648
E03.8 Other specified hypothyroidism
0.000 0.439 0.561
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.446 0.554
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.453 0.547
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.463 0.537
M07.38 Other psoriatic arthropathies (Other)
0.000 0.487 0.513
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.487 0.513
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.487 0.513
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.487 0.513
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.487 0.513
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.487 0.513
E03.5 Myxoedema coma
0.000 0.535 0.464
E03.4 Atrophy of thyroid (acquired)
0.000 0.535 0.464
E03.3 Postinfectious hypothyroidism
0.000 0.535 0.464
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.578 0.422
E03.1 Congenital hypothyroidism without goitre
0.000 0.592 0.408
G35 Multiple sclerosis
0.000 0.624 0.376
M07 Psoriatic and enteropathic arthropathies
0.001 0.698 0.301
K90 Intestinal malabsorption
0.000 0.756 0.244
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.757 0.243
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.781 0.219
M07.6 Other enteropathic arthropathies
0.001 0.784 0.216
M07.5 Arthropathy in ulcerative colitis
0.001 0.784 0.216
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.001 0.784 0.216
M07.2 Psoriatic spondylitis
0.001 0.784 0.216
M07.1 Arthritis mutilans
0.001 0.784 0.216
M07.0 Distal interphalangeal psoriatic arthropathy
0.001 0.784 0.216
G30-G32 Other degenerative diseases of the nervous system
0.000 0.785 0.215
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.792 0.208
L40-L45 Papulosquamous disorders
0.000 0.798 0.202
Chapter VI Diseases of the nervous system
0.000 0.798 0.202
G31.2 Degeneration of nervous system due to alcohol
0.000 0.801 0.199
G31.8 Other specified degenerative diseases of nervous system
0.000 0.802 0.198
G30 Alzheimer's disease
0.000 0.809 0.191
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.814 0.186
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.823 0.177
G62 Other polyneuropathies
0.000 0.823 0.177
K90.3 Pancreatic steatorrhoea
0.000 0.825 0.175
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.825 0.175
K90.1 Tropical sprue
0.000 0.825 0.175
G62.9 Polyneuropathy, unspecified
0.000 0.826 0.174
G30.9 Alzheimer's disease, unspecified
0.000 0.829 0.171
G31.0 Circumscribed brain atrophy
0.000 0.831 0.169
K90.8 Other intestinal malabsorption
0.000 0.832 0.167
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.835 0.165
G36 Other acute disseminated demyelination
0.000 0.837 0.163
G70-G73 Diseases of myoneural junction and muscle
0.000 0.842 0.158
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.843 0.157
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.001 0.845 0.155
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.001 0.845 0.155
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.001 0.845 0.155
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.001 0.845 0.155
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.001 0.845 0.155
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.001 0.845 0.155
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.001 0.845 0.155
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.001 0.845 0.155
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.001 0.845 0.155
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.001 0.845 0.155
M07.19 Arthritis mutilans (Site unspecified)
0.001 0.845 0.155
M07.18 Arthritis mutilans (Other)
0.001 0.845 0.155
M07.17 Arthritis mutilans (Ankle and foot)
0.001 0.845 0.155
M07.16 Arthritis mutilans (Lower leg)
0.001 0.845 0.155
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.001 0.845 0.155
M07.14 Arthritis mutilans (Hand)
0.001 0.845 0.155
M07.13 Arthritis mutilans (Forearm)
0.001 0.845 0.155
M07.12 Arthritis mutilans (Upper arm)
0.001 0.845 0.155
M07.11 Arthritis mutilans (Shoulder region)
0.001 0.845 0.155
M07.10 Arthritis mutilans (Multiple sites)
0.001 0.845 0.155
M07.29 Psoriatic spondylitis (Site unspecified)
0.001 0.845 0.155
M07.28 Psoriatic spondylitis (Other)
0.001 0.845 0.155
M07.27 Psoriatic spondylitis (Ankle and foot)
0.001 0.845 0.155
M07.26 Psoriatic spondylitis (Lower leg)
0.001 0.845 0.155
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.001 0.845 0.155
M07.24 Psoriatic spondylitis (Hand)
0.001 0.845 0.155
M07.23 Psoriatic spondylitis (Forearm)
0.001 0.845 0.155
M07.22 Psoriatic spondylitis (Upper arm)
0.001 0.845 0.155
M07.21 Psoriatic spondylitis (Shoulder region)
0.001 0.845 0.155
M07.20 Psoriatic spondylitis (Multiple sites)
0.001 0.845 0.155
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.001 0.845 0.155
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.001 0.845 0.155
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.001 0.845 0.155
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.001 0.845 0.155
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.001 0.845 0.155
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.001 0.845 0.155
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.001 0.845 0.155
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.001 0.845 0.155
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.001 0.845 0.155
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.001 0.845 0.155
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.001 0.845 0.155
M07.58 Arthropathy in ulcerative colitis (Other)
0.001 0.845 0.155
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.001 0.845 0.155
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.001 0.845 0.155
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.001 0.845 0.155
M07.54 Arthropathy in ulcerative colitis (Hand)
0.001 0.845 0.155
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.001 0.845 0.155
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.001 0.845 0.155
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.001 0.845 0.155
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.001 0.845 0.155
M07.69 Other enteropathic arthropathies (Site unspecified)
0.001 0.845 0.155
M07.68 Other enteropathic arthropathies (Other)
0.001 0.845 0.155
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.001 0.845 0.155
M07.66 Other enteropathic arthropathies (Lower leg)
0.001 0.845 0.155
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.001 0.845 0.155
M07.64 Other enteropathic arthropathies (Hand)
0.001 0.845 0.155
M07.63 Other enteropathic arthropathies (Forearm)
0.001 0.845 0.155
M07.62 Other enteropathic arthropathies (Upper arm)
0.001 0.845 0.155
M07.61 Other enteropathic arthropathies (Shoulder region)
0.001 0.845 0.155
M07.60 Other enteropathic arthropathies (Multiple sites)
0.001 0.845 0.155
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.849 0.151
G03 Meningitis due to other and unspecified causes
0.000 0.849 0.151
G06 Intracranial and intraspinal abscess and granuloma
0.000 0.854 0.146
L44 Other papulosquamous disorders
0.000 0.855 0.145
L41 Parapsoriasis
0.000 0.855 0.145
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.855 0.145
G00 Bacterial meningitis, not elsewhere classified
0.000 0.855 0.144
G30.0 Alzheimer's disease with early onset
0.000 0.857 0.143
G30.1 Alzheimer's disease with late onset
0.000 0.858 0.142
G09 Sequelae of inflammatory diseases of central nervous system
0.000 0.859 0.141
G62.1 Alcoholic polyneuropathy
0.000 0.859 0.141
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.860 0.140
G60 Hereditary and idiopathic neuropathy
0.000 0.861 0.139
L42 Pityriasis rosea
0.000 0.864 0.135
G30.8 Other Alzheimer's disease
0.000 0.865 0.135
G61 Inflammatory polyneuropathy
0.000 0.866 0.134
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.000 0.866 0.134
G64 Other disorders of peripheral nervous system
0.000 0.866 0.134
K90.9 Intestinal malabsorption, unspecified
0.000 0.866 0.134
G03.9 Meningitis, unspecified
0.000 0.869 0.131
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.871 0.129
G01 Meningitis in bacterial diseases classified elsewhere
0.000 0.871 0.129
G71 Primary disorders of muscles
0.000 0.872 0.128
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.000 0.873 0.127
G62.2 Polyneuropathy due to other toxic agents
0.000 0.873 0.127
G83 Other paralytic syndromes
0.000 0.873 0.127
N39.3 Stress incontinence
0.124 0.876 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.000 0.880 0.119
G00.1 Pneumococcal meningitis
0.000 0.881 0.119
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.000 0.882 0.118
G06.0 Intracranial abscess and granuloma
0.000 0.882 0.118
G83.4 Cauda equina syndrome
0.000 0.883 0.117
G36.9 Acute disseminated demyelination, unspecified
0.000 0.883 0.117
G36.8 Other specified acute disseminated demyelination
0.000 0.883 0.117
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.883 0.117
G70 Myasthenia gravis and other myoneural disorders
0.000 0.884 0.116
G06.1 Intraspinal abscess and granuloma
0.000 0.886 0.114
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.000 0.886 0.114
G60.0 Hereditary motor and sensory neuropathy
0.000 0.887 0.113
G61.8 Other inflammatory polyneuropathies
0.000 0.887 0.112
G71.3 Mitochondrial myopathy, not elsewhere classified
0.000 0.889 0.111
G72 Other myopathies
0.000 0.889 0.111
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.000 0.890 0.110
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.000 0.890 0.110
G62.8 Other specified polyneuropathies
0.000 0.890 0.110
G37 Other demyelinating diseases of central nervous system
0.000 0.891 0.109
G03.8 Meningitis due to other specified causes
0.000 0.892 0.108
G03.2 Benign recurrent meningitis [Mollaret]
0.000 0.892 0.108
G03.1 Chronic meningitis
0.000 0.892 0.108
G03.0 Nonpyogenic meningitis
0.000 0.892 0.108
G83.9 Paralytic syndrome, unspecified
0.000 0.892 0.108
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.893 0.107
G00.9 Bacterial meningitis, unspecified
0.000 0.893 0.107
G04 Encephalitis, myelitis and encephalomyelitis
0.000 0.893 0.106
G36.0 Neuromyelitis optica [Devic]
0.000 0.895 0.105
L41.9 Parapsoriasis, unspecified
0.000 0.896 0.104
L41.8 Other parapsoriasis
0.000 0.896 0.104
L41.5 Retiform parapsoriasis
0.000 0.896 0.104
L41.4 Large plaque parapsoriasis
0.000 0.896 0.104
L41.3 Small plaque parapsoriasis
0.000 0.896 0.104
L41.2 Lymphomatoid papulosis
0.000 0.896 0.104
L41.1 Pityriasis lichenoides chronica
0.000 0.896 0.104
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.896 0.104
L44.9 Papulosquamous disorder, unspecified
0.000 0.896 0.104
L44.8 Other specified papulosquamous disorders
0.000 0.896 0.104
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.896 0.104
L44.3 Lichen ruber moniliformis
0.000 0.896 0.104
L44.2 Lichen striatus
0.000 0.896 0.104
L44.1 Lichen nitidus
0.000 0.896 0.104
L44.0 Pityriasis rubra pilaris
0.000 0.896 0.104
G00.8 Other bacterial meningitis
0.000 0.896 0.104
G00.3 Staphylococcal meningitis
0.000 0.896 0.104
G00.2 Streptococcal meningitis
0.000 0.896 0.104
G00.0 Haemophilus meningitis
0.000 0.896 0.104
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.000 0.897 0.103
G06.2 Extradural and subdural abscess, unspecified
0.000 0.898 0.102
G60.3 Idiopathic progressive neuropathy
0.000 0.900 0.100
G60.2 Neuropathy in association with hereditary ataxia
0.000 0.900 0.100
G60.1 Refsum's disease
0.000 0.900 0.100
G62.0 Drug-induced polyneuropathy
0.000 0.902 0.098
G60.9 Hereditary and idiopathic neuropathy, unspecified
0.000 0.902 0.098
G61.1 Serum neuropathy
0.000 0.903 0.096
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.000 0.904 0.096
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.000 0.904 0.096
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.000 0.904 0.096
G83.1 Monoplegia of lower limb
0.000 0.905 0.094
G71.1 Myotonic disorders
0.000 0.907 0.092
G81 Hemiplegia
0.000 0.908 0.092
G71.9 Primary disorder of muscle, unspecified
0.000 0.908 0.092
G71.8 Other primary disorders of muscles
0.000 0.908 0.092
G71.2 Congenital myopathies
0.000 0.908 0.092
G70.0 Myasthenia gravis
0.000 0.908 0.092
G83.5 Locked-in syndrome
0.000 0.909 0.091
G83.3 Monoplegia, unspecified
0.000 0.909 0.091
G83.0 Diplegia of upper limbs
0.000 0.909 0.091
G60.8 Other hereditary and idiopathic neuropathies
0.000 0.910 0.090
G61.9 Inflammatory polyneuropathy, unspecified
0.000 0.912 0.088
G63.8 Polyneuropathy in other diseases classified elsewhere
0.000 0.914 0.086
G63.6 Polyneuropathy in other musculoskeletal disorders
0.000 0.914 0.086
G63.5 Polyneuropathy in systemic connective tissue disorders
0.000 0.914 0.086
G63.4 Polyneuropathy in nutritional deficiency
0.000 0.914 0.086
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.000 0.914 0.086
G63.1 Polyneuropathy in neoplastic disease
0.000 0.914 0.086
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.000 0.914 0.086
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.916 0.084
G70.8 Other specified myoneural disorders
0.000 0.916 0.083
G70.2 Congenital and developmental myasthenia
0.000 0.916 0.083
G70.1 Toxic myoneural disorders
0.000 0.916 0.083
G12 Spinal muscular atrophy and related syndromes
0.000 0.918 0.082
G83.8 Other specified paralytic syndromes
0.000 0.918 0.082
G73.7 Myopathy other diseases classified elsewhere
0.000 0.918 0.082
G73.6 Myopathy in metabolic diseases
0.000 0.918 0.082
G73.5 Myopathy in endocrine diseases
0.000 0.918 0.082
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere
0.000 0.918 0.082
G73.3 Myasthenic syndromes in other diseases classified elsewhere
0.000 0.918 0.082
G73.2 Other myasthenic syndromes in neoplastic disease
0.000 0.918 0.082
G73.1 Eaton-Lambert syndrome
0.000 0.918 0.082
G73.0 Myasthenic syndromes in endocrine diseases
0.000 0.918 0.082
G61.0 Guillain-Barre syndrome
0.000 0.919 0.081
G72.8 Other specified myopathies
0.000 0.919 0.081
G72.0 Drug-induced myopathy
0.000 0.919 0.080
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.000 0.920 0.080
G72.3 Periodic paralysis
0.000 0.920 0.080
G72.2 Myopathy due to other toxic agents
0.000 0.920 0.080
G72.1 Alcoholic myopathy
0.000 0.920 0.080
G71.0 Muscular dystrophy
0.000 0.920 0.080
G72.9 Myopathy, unspecified
0.000 0.920 0.080
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.000 0.921 0.079
G02.1 Meningitis in mycoses
0.000 0.921 0.079
G37.5 Concentric sclerosis [Balo]
0.000 0.921 0.078
G37.4 Subacute necrotising myelitis
0.000 0.921 0.078
G37.2 Central pontine myelinolysis
0.000 0.921 0.078
G37.1 Central demyelination of corpus callosum
0.000 0.921 0.078
G37.0 Diffuse sclerosis
0.000 0.921 0.078
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.000 0.923 0.077
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.000 0.923 0.076
G04.1 Tropical spastic paraplegia
0.000 0.923 0.076
G81.1 Spastic hemiplegia
0.000 0.924 0.076
G70.9 Myoneural disorder, unspecified
0.000 0.924 0.076
G82 Paraplegia and tetraplegia
0.000 0.925 0.075
G72.4 Inflammatory myopathy, not elsewhere classified
0.000 0.926 0.074
G80 Infantile cerebral palsy
0.000 0.926 0.074
G63.2 Diabetic polyneuropathy
0.000 0.928 0.072
G14 Postpolio syndrome
0.000 0.932 0.067
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.000 0.933 0.067
G83.2 Monoplegia of upper limb
0.000 0.933 0.067
G81.0 Flaccid hemiplegia
0.000 0.934 0.066
G11 Hereditary ataxia
0.000 0.934 0.065
G12.2 Motor neuron disease
0.000 0.936 0.064
G10 Huntington's disease
0.000 0.937 0.063
G04.0 Acute disseminated encephalitis
0.000 0.937 0.062
G02.0 Meningitis in viral diseases classified elsewhere
0.000 0.938 0.062
G82.1 Spastic paraplegia
0.000 0.941 0.059
G12.9 Spinal muscular atrophy, unspecified
0.000 0.941 0.059
G12.8 Other spinal muscular atrophies and related syndromes
0.000 0.941 0.059
G12.1 Other inherited spinal muscular atrophy
0.000 0.941 0.059
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.000 0.941 0.059
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.941 0.059
L43 Lichen planus
0.001 0.941 0.058
D64.9 Anaemia, unspecified
0.000 0.942 0.058
G20-G26 Extrapyramidal and movement disorders
0.000 0.943 0.057
M45-M49 Spondylopathies
0.000 0.944 0.056
D64 Other anaemias
0.000 0.944 0.056
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere
0.000 0.944 0.055
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema
0.000 0.944 0.055
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease
0.000 0.944 0.055
G13.0 Paraneoplastic neuromyopathy and neuropathy
0.000 0.944 0.055
G80.2 Infantile hemiplegia
0.000 0.945 0.055
G80.0 Spastic cerebral palsy
0.000 0.945 0.055
G82.3 Flaccid tetraplegia
0.000 0.946 0.054
G82.0 Flaccid paraplegia
0.000 0.946 0.054
G80.8 Other infantile cerebral palsy
0.000 0.947 0.053
G80.4 Ataxic cerebral palsy
0.000 0.947 0.053
G80.3 Dyskinetic cerebral palsy
0.000 0.947 0.053
G82.5 Tetraplegia, unspecified
0.000 0.947 0.053
G82.4 Spastic tetraplegia
0.000 0.947 0.053
K75 Other inflammatory liver diseases
0.000 0.949 0.051
D60-D64 Aplastic and other anaemias
0.000 0.949 0.051
D61.9 Aplastic anaemia, unspecified
0.000 0.950 0.050
K75.0 Abscess of liver
0.000 0.950 0.050
D50-D53 Nutritional anaemias
0.000 0.950 0.050
K75.8 Other specified inflammatory liver diseases
0.000 0.950 0.050
D61 Other aplastic anaemias
0.000 0.950 0.050
K75.4 Autoimmune hepatitis
0.000 0.951 0.049
D50 Iron deficiency anaemia
0.000 0.951 0.049
G11.4 Hereditary spastic paraplegia
0.000 0.951 0.049
E00-E07 Disorders of thyroid gland
0.000 0.952 0.048
D64.8 Other specified anaemias
0.000 0.952 0.048
D50.9 Iron deficiency anaemia, unspecified
0.000 0.952 0.048
G11.8 Other hereditary ataxias
0.000 0.953 0.047
G11.3 Cerebellar ataxia with defective DNA repair
0.000 0.953 0.047
G11.2 Late-onset cerebellar ataxia
0.000 0.953 0.047
G11.0 Congenital nonprogressive ataxia
0.000 0.953 0.047
G90-G99 Other disorders of the nervous system
0.000 0.953 0.047
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.953 0.047
G80.1 Spastic diplegia
0.000 0.954 0.046
D80-D89 Certain disorders involving the immune mechanism
0.000 0.955 0.045
D51 Vitamin B12 deficiency anaemia
0.000 0.956 0.044
G11.1 Early-onset cerebellar ataxia
0.000 0.956 0.043
K70-K77 Diseases of liver
0.000 0.956 0.044
K70 Alcoholic liver disease
0.000 0.957 0.043
D52 Folate deficiency anaemia
0.000 0.957 0.043
L43.3 Subacute (active) lichen planus
0.001 0.958 0.042
L43.2 Lichenoid drug reaction
0.001 0.958 0.042
L43.1 Bullous lichen planus
0.001 0.958 0.042
L43.0 Hypertrophic lichen planus
0.001 0.958 0.042
G98 Other disorders of nervous system, not elsewhere classified
0.000 0.958 0.042
K72 Hepatic failure, not elsewhere classified
0.000 0.958 0.042
G21 Secondary Parkinsonism
0.000 0.959 0.041
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.000 0.959 0.041
G22 Parkinsonism in diseases classified elsewhere
0.000 0.959 0.041
G25 Other extrapyramidal and movement disorders
0.000 0.959 0.041
D80 Immunodeficiency with predominantly antibody defects
0.000 0.959 0.041
G93 Other disorders of brain
0.000 0.959 0.041
D50.8 Other iron deficiency anaemias
0.000 0.960 0.040
D64.4 Congenital dyserythropoietic anaemia
0.000 0.960 0.040
D64.3 Other sideroblastic anaemias
0.000 0.960 0.040
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.960 0.040
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.960 0.040
D64.0 Hereditary sideroblastic anaemia
0.000 0.960 0.040
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.960 0.040
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.960 0.040
G93.0 Cerebral cysts
0.000 0.961 0.039
K73 Chronic hepatitis, not elsewhere classified
0.000 0.961 0.039
K70.1 Alcoholic hepatitis
0.000 0.961 0.039
K72.9 Hepatic failure, unspecified
0.000 0.961 0.039
G11.9 Hereditary ataxia, unspecified
0.000 0.961 0.038
G23 Other degenerative diseases of basal ganglia
0.000 0.961 0.038
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.001 0.962 0.038
D53 Other nutritional anaemias
0.000 0.962 0.038
G81.9 Hemiplegia, unspecified
0.000 0.962 0.038
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.962 0.038
D52.9 Folate deficiency anaemia, unspecified
0.000 0.963 0.037
K70.0 Alcoholic fatty liver
0.000 0.963 0.037
K75.2 Nonspecific reactive hepatitis
0.000 0.963 0.037
K75.1 Phlebitis of portal vein
0.000 0.963 0.037
K72.0 Acute and subacute hepatic failure
0.000 0.963 0.037
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.963 0.037
E07 Other disorders of thyroid
0.000 0.963 0.037
N39 Other disorders of urinary system
0.037 0.963 0.000
K70.4 Alcoholic hepatic failure
0.000 0.964 0.036
D61.8 Other specified aplastic anaemias
0.000 0.964 0.036
D61.3 Idiopathic aplastic anaemia
0.000 0.964 0.036
D61.2 Aplastic anaemia due to other external agents
0.000 0.964 0.036
D86 Sarcoidosis
0.000 0.964 0.036
M46 Other inflammatory spondylopathies
0.000 0.964 0.036
G93.5 Compression of brain
0.000 0.964 0.036
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.964 0.035
D50.1 Sideropenic dysphagia
0.000 0.965 0.035
G94 Other disorders of brain in diseases classified elsewhere
0.000 0.965 0.035
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.965 0.035
E00 Congenital iodine-deficiency syndrome
0.000 0.965 0.035
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.965 0.035
M49 Spondylopathies in diseases classified elsewhere
0.000 0.965 0.034
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.966 0.034
G92 Toxic encephalopathy
0.000 0.966 0.034
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.966 0.034
G25.0 Essential tremor
0.000 0.966 0.034
D61.0 Constitutional aplastic anaemia
0.000 0.966 0.033
K73.9 Chronic hepatitis, unspecified
0.000 0.967 0.033
E07.8 Other specified disorders of thyroid
0.000 0.967 0.033
D83 Common variable immunodeficiency
0.000 0.967 0.033
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.967 0.033
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.967 0.033
G91 Hydrocephalus
0.000 0.967 0.033
N39.8 Other specified disorders of urinary system
0.033 0.967 0.000
D55-D59 Haemolytic anaemias
0.000 0.967 0.033
D61.1 Drug-induced aplastic anaemia
0.000 0.967 0.032
D81 Combined immunodeficiencies
0.000 0.967 0.032
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.000 0.967 0.032
G25.3 Myoclonus
0.000 0.967 0.032
G93.8 Other specified disorders of brain
0.000 0.967 0.033
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.968 0.032
D84 Other immunodeficiencies
0.000 0.968 0.032
D51.2 Transcobalamin II deficiency
0.000 0.968 0.032
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.968 0.032
D86.3 Sarcoidosis of skin
0.000 0.968 0.032
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.968 0.032
G80.9 Infantile cerebral palsy, unspecified
0.000 0.968 0.031
D86.0 Sarcoidosis of lung
0.000 0.968 0.032
K77 Liver disorders in diseases classified elsewhere
0.000 0.968 0.031
G25.2 Other specified forms of tremor
0.000 0.969 0.031
M35.0 Sicca syndrome [Sjogren]
0.000 0.969 0.031
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.969 0.031
D52.8 Other folate deficiency anaemias
0.000 0.969 0.031
D52.1 Drug-induced folate deficiency anaemia
0.000 0.969 0.031
D52.0 Dietary folate deficiency anaemia
0.000 0.969 0.031
N39.9 Disorder of urinary system, unspecified
0.031 0.969 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.969 0.031
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.969 0.031
K70.9 Alcoholic liver disease, unspecified
0.000 0.969 0.031
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.970 0.030
G93.1 Anoxic brain damage, not elsewhere classified
0.000 0.970 0.030
G24 Dystonia
0.000 0.970 0.030
D53.9 Nutritional anaemia, unspecified
0.000 0.970 0.030
G21.9 Secondary Parkinsonism, unspecified
0.000 0.970 0.030
G21.8 Other secondary Parkinsonism
0.000 0.970 0.030
G21.4 Vascular parkinsonism
0.000 0.970 0.030
G21.3 Postencephalitic Parkinsonism
0.000 0.970 0.030
G21.2 Secondary Parkinsonism due to other external agents
0.000 0.970 0.030
G21.1 Other drug-induced secondary Parkinsonism
0.000 0.970 0.030
G21.0 Malignant neuroleptic syndrome
0.000 0.970 0.030
R31 Unspecified haematuria
0.030 0.970 0.000
D89.1 Cryoglobulinaemia
0.000 0.970 0.030
G25.6 Drug-induced tics and other tics of organic origin
0.000 0.970 0.029
G25.5 Other chorea
0.000 0.970 0.029
G25.4 Drug-induced chorea
0.000 0.970 0.029
G25.1 Drug-induced tremor
0.000 0.970 0.029
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.971 0.029
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.971 0.029
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.971 0.029
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.971 0.029
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.971 0.029
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.971 0.029
G93.7 Reye's syndrome
0.000 0.971 0.029
D82 Immunodeficiency associated with other major defects
0.000 0.971 0.029
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.971 0.029
D89.3 Immune reconstitution syndrome
0.000 0.971 0.029
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.971 0.029
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.971 0.029
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.972 0.028
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.972 0.028
K72.1 Chronic hepatic failure
0.000 0.972 0.028
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.972 0.028
G94.1 Hydrocephalus in neoplastic disease
0.000 0.972 0.028
G23.9 Degenerative disease of basal ganglia, unspecified
0.000 0.972 0.028
G23.3 Multiple system atrophy, cerebellar type
0.000 0.972 0.028
G23.2 Striatonigral degeneration
0.000 0.972 0.028
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.000 0.972 0.028
G23.0 Hallervorden-Spatz disease
0.000 0.972 0.028
D53.8 Other specified nutritional anaemias
0.000 0.972 0.028
D53.2 Scorbutic anaemia
0.000 0.972 0.028
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.972 0.028
D53.0 Protein deficiency anaemia
0.000 0.972 0.028
K70.3 Alcoholic cirrhosis of liver
0.000 0.972 0.028
N39.1 Persistent proteinuria, unspecified
0.028 0.972 0.000
G93.4 Encephalopathy, unspecified
0.000 0.972 0.028
M46.0 Spinal enthesopathy
0.000 0.972 0.027
G93.9 Disorder of brain, unspecified
0.000 0.973 0.027
G25.9 Extrapyramidal and movement disorder, unspecified
0.000 0.973 0.027
G97.8 Other postprocedural disorders of nervous system
0.000 0.973 0.027
K71 Toxic liver disease
0.000 0.973 0.027
G93.2 Benign intracranial hypertension
0.000 0.973 0.027
L43.8 Other lichen planus
0.001 0.973 0.025
G91.1 Obstructive hydrocephalus
0.000 0.973 0.027
M46.9 Inflammatory spondylopathy, unspecified
0.000 0.973 0.027
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.973 0.026
D60.8 Other acquired pure red cell aplasias
0.000 0.973 0.026
D60.1 Transient acquired pure red cell aplasia
0.000 0.973 0.026
D60.0 Chronic acquired pure red cell aplasia
0.000 0.973 0.026
D84.9 Immunodeficiency, unspecified
0.000 0.973 0.027
D86.1 Sarcoidosis of lymph nodes
0.000 0.973 0.027
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.973 0.026
E07.1 Dyshormogenetic goitre
0.000 0.973 0.026
E07.0 Hypersecretion of calcitonin
0.000 0.973 0.026
N39.2 Orthostatic proteinuria, unspecified
0.026 0.973 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.000 0.974 0.026
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.974 0.026
M46.2 Osteomyelitis of vertebra
0.000 0.974 0.026
M46.8 Other specified inflammatory spondylopathies
0.000 0.974 0.026
M46.5 Other infective spondylopathies
0.000 0.974 0.026
D59 Acquired haemolytic anaemia
0.000 0.974 0.026
M46.1 Sacro-iliitis, not elsewhere classified
0.000 0.974 0.026
G94.8 Other specified disorders of brain in diseases classified elsewhere
0.000 0.974 0.025
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere
0.000 0.974 0.025
E05.9 Thyrotoxicosis, unspecified
0.000 0.975 0.025
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.975 0.025

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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