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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3891492
log Bayes Factor = 21.8058
Chromosome 6   position 29,831,052  (GRCh37) Explore rs3891492 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.005 0.995
E16 Other disorders of pancreatic internal secretion
0.000 0.008 0.992
E70-E90 Metabolic disorders
0.000 0.008 0.992
E83 Disorders of mineral metabolism
0.000 0.009 0.991
E16.2 Hypoglycaemia, unspecified
0.000 0.009 0.991
E00-E07 Disorders of thyroid gland
0.000 0.019 0.981
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.021 0.979
E05.9 Thyrotoxicosis, unspecified
0.000 0.030 0.970
E10.1 With ketoacidosis
0.000 0.032 0.968
E10.4 With neurological complications
0.000 0.032 0.968
E10.9 Without complications
0.000 0.039 0.961
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.047 0.953
E10.3 With ophthalmic complications
0.000 0.060 0.940
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.094 0.906
E14 Unspecified diabetes mellitus
0.000 0.106 0.894
M06.9 Rheumatoid arthritis, unspecified
0.000 0.106 0.894
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.107 0.893
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.116 0.884
E14.3 With ophthalmic complications
0.000 0.130 0.870
E10.0 With coma
0.000 0.142 0.858
E85 Amyloidosis
0.000 0.151 0.849
E50-E64 Other nutritional deficiencies
0.000 0.151 0.849
E80.4 Gilbert's syndrome
0.000 0.164 0.836
E10.6 With other specified complications
0.000 0.171 0.829
E10.5 With peripheral circulatory complications
0.000 0.183 0.817
E53 Deficiency of other B group vitamins
0.000 0.196 0.804
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.215 0.785
E53.8 Deficiency of other specified B group vitamins
0.000 0.228 0.772
E73 Lactose intolerance
0.000 0.229 0.771
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.236 0.764
E74 Other disorders of carbohydrate metabolism
0.000 0.242 0.758
E03 Other hypothyroidism
0.000 0.245 0.755
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.249 0.751
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.256 0.744
E11 Non-insulin-dependent diabetes mellitus
0.000 0.263 0.737
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.266 0.734
E16.1 Other hypoglycaemia
0.000 0.274 0.726
E79 Disorders of purine and pyrimidine metabolism
0.000 0.275 0.724
E11.3 With ophthalmic complications
0.000 0.276 0.724
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.280 0.720
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.280 0.720
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E85.9 Amyloidosis, unspecified
0.000 0.284 0.716
E15 Nondiabetic hypoglycaemic coma
0.000 0.286 0.714
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.288 0.712
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.288 0.712
E16.4 Abnormal secretion of gastrin
0.000 0.288 0.712
E16.3 Increased secretion of glucagon
0.000 0.288 0.712
E77 Disorders of glycoprotein metabolism
0.000 0.289 0.711
E76 Disorders of glycosaminoglycan metabolism
0.000 0.289 0.711
E72 Other disorders of amino-acid metabolism
0.000 0.289 0.711
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.289 0.711
E70 Disorders of aromatic amino-acid metabolism
0.000 0.289 0.711
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.289 0.711
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.289 0.710
E83.8 Other disorders of mineral metabolism
0.000 0.289 0.710
E83.2 Disorders of zinc metabolism
0.000 0.289 0.710
E83.0 Disorders of copper metabolism
0.000 0.289 0.710
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.297 0.703
E00 Congenital iodine-deficiency syndrome
0.000 0.297 0.703
E10.2 With renal complications
0.000 0.297 0.703
E05.5 Thyroid crisis or storm
0.000 0.298 0.702
E05.4 Thyrotoxicosis factitia
0.000 0.298 0.702
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.298 0.702
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.298 0.702
E84 Cystic fibrosis
0.000 0.305 0.695
E10.8 With unspecified complications
0.000 0.308 0.692
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.312 0.688
E13 Other specified diabetes mellitus
0.000 0.319 0.680
E05.8 Other thyrotoxicosis
0.000 0.320 0.679
E80.2 Other porphyria
0.000 0.321 0.679
E03.9 Hypothyroidism, unspecified
0.000 0.324 0.676
E14.5 With peripheral circulatory complications
0.000 0.329 0.671
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.342 0.658
E80.1 Porphyria cutanea tarda
0.000 0.343 0.657
E14.6 With other specified complications
0.000 0.344 0.656
E40-E46 Malnutrition
0.000 0.345 0.655
E14.1 With ketoacidosis
0.000 0.346 0.654
E85.4 Organ-limited amyloidosis
0.000 0.347 0.653
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.350 0.650
E80.5 Crigler-Najjar syndrome
0.000 0.350 0.650
E80.3 Defects of catalase and peroxydase
0.000 0.350 0.650
E80.0 Hereditary erythropoietic porphyria
0.000 0.350 0.650
E80.6 Other disorders of bilirubin metabolism
0.000 0.350 0.649
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.351 0.649
E14.7 With multiple complications
0.000 0.359 0.641
E14.0 With coma
0.000 0.359 0.641
E14.4 With neurological complications
0.000 0.366 0.634
E07 Other disorders of thyroid
0.000 0.373 0.627
E89.2 Postprocedural hypoparathyroidism
0.000 0.374 0.626
E88 Other metabolic disorders
0.000 0.376 0.624
E14.2 Withrenal complications
0.000 0.379 0.621
E85.3 Secondary systemic amyloidosis
0.000 0.380 0.620
M06 Other rheumatoid arthritis
0.000 0.382 0.618
E58 Dietary calcium deficiency
0.000 0.383 0.617
E14.8 With unspecified complications
0.000 0.384 0.616
E73.9 Lactose intolerance, unspecified
0.000 0.387 0.613
E85.8 Other amyloidosis
0.000 0.392 0.608
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.392 0.608
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.392 0.608
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.392 0.608
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.392 0.608
E63 Other nutritional deficiencies
0.000 0.392 0.608
E56 Other vitamin deficiencies
0.000 0.392 0.608
E50 Vitamin A deficiency
0.000 0.392 0.608
E60 Dietary zinc deficiency
0.000 0.392 0.608
E59 Dietary selenium deficiency
0.000 0.392 0.608
E54 Ascorbic acid deficiency
0.000 0.392 0.608
E52 Niacin deficiency [pellagra]
0.000 0.392 0.608
E51 Thiamine deficiency
0.000 0.405 0.595
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.409 0.591
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.413 0.587
E53.9 Vitamin B deficiency, unspecified
0.000 0.421 0.579
E53.1 Pyridoxine deficiency
0.000 0.423 0.576
E53.0 Riboflavin deficiency
0.000 0.423 0.576
E89.0 Postprocedural hypothyroidism
0.000 0.427 0.573
E65-E68 Obesity and other hyperalimentation
0.000 0.445 0.555
E73.8 Other lactose intolerance
0.000 0.447 0.553
E73.1 Secondary lactase deficiency
0.000 0.447 0.553
E73.0 Congenital lactase deficiency
0.000 0.447 0.553
E61 Deficiency of other nutrient elements
0.000 0.453 0.547
E11.0 With coma
0.000 0.454 0.546
E11.1 With ketoacidosis
0.000 0.455 0.545
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.456 0.544
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.456 0.544
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.456 0.544
E74.2 Disorders of galactose metabolism
0.000 0.456 0.544
E74.1 Disorders of fructose metabolism
0.000 0.456 0.544
E74.0 Glycogen storage disease
0.000 0.456 0.544
E03.5 Myxoedema coma
0.000 0.458 0.541
E03.4 Atrophy of thyroid (acquired)
0.000 0.458 0.541
E03.3 Postinfectious hypothyroidism
0.000 0.458 0.541
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.458 0.541
E03.8 Other specified hypothyroidism
0.000 0.460 0.540
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.461 0.539
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.461 0.539
E89.5 Postprocedural testicular hypofunction
0.000 0.461 0.539
E89.4 Postprocedural ovarian failure
0.000 0.461 0.539
E89.1 Postprocedural hypoinsulinaemia
0.000 0.461 0.539
E11.8 With unspecified complications
0.000 0.462 0.538
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.467 0.533
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.471 0.529
E11.7 With multiple complications
0.000 0.471 0.528
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.475 0.525
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.480 0.519
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.480 0.519
E79.1 Lesch-Nyhan syndrome
0.000 0.480 0.519
E11.5 With peripheral circulatory complications
0.000 0.483 0.517
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.490 0.510
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.490 0.510
E70.3 Albinism
0.000 0.490 0.510
E70.2 Disorders of tyrosine metabolism
0.000 0.490 0.510
E70.1 Other hyperphenylalaninaemias
0.000 0.490 0.510
E70.0 Classical phenylketonuria
0.000 0.490 0.510
E71.3 Disorders of fatty-acid metabolism
0.000 0.490 0.510
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.490 0.510
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.490 0.510
E71.0 Maple-syrup-urine disease
0.000 0.490 0.510
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.490 0.510
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.490 0.510
E72.5 Disorders of glycine metabolism
0.000 0.490 0.510
E72.4 Disorders of ornithine metabolism
0.000 0.490 0.510
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.490 0.510
E72.2 Disorders of urea cycle metabolism
0.000 0.490 0.510
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.490 0.510
E72.0 Disorders of amino-acid transport
0.000 0.490 0.510
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.490 0.510
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.490 0.510
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.490 0.510
E76.2 Other mucopolysaccharidoses
0.000 0.490 0.510
E76.1 Mucopolysaccharidosis, type II
0.000 0.490 0.510
E76.0 Mucopolysaccharidosis, type I
0.000 0.490 0.510
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.490 0.510
E77.8 Other disorders of glycoprotein metabolism
0.000 0.490 0.510
E77.1 Defects in glycoprotein degradation
0.000 0.490 0.510
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.490 0.510
E83.3 Disorders of phosphorus metabolism
0.000 0.491 0.509
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.495 0.505
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.496 0.504
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.496 0.504
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.496 0.504
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.496 0.504
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.496 0.504
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.496 0.504
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.496 0.504
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.496 0.504
E84.8 Cystic fibrosis with other manifestations
0.000 0.501 0.498
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.501 0.498
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.501 0.498
E11.4 With neurological complications
0.000 0.502 0.498
E03.1 Congenital hypothyroidism without goitre
0.000 0.504 0.495
E13.8 With unspecified complications
0.000 0.512 0.488
E13.7 With multiple complications
0.000 0.512 0.488
E13.6 With other specified complications
0.000 0.512 0.488
E13.5 With peripheral circulatory complications
0.000 0.512 0.488
E13.4 With neurological complications
0.000 0.512 0.488
E13.3 With ophthalmic complications
0.000 0.512 0.488
E13.2 With renal complications
0.000 0.512 0.488
E13.1 With ketoacidosis
0.000 0.512 0.488
E13.0 With coma
0.000 0.512 0.488
M06.4 Inflammatory polyarthropathy
0.000 0.515 0.485
E84.9 Cystic fibrosis, unspecified
0.000 0.517 0.483
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.519 0.481
E89.3 Postprocedural hypopituitarism
0.000 0.522 0.478
M06.3 Rheumatoid nodule
0.000 0.523 0.477
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.530 0.470
E45 Retarded development following protein-energy malnutrition
0.000 0.530 0.470
E43 Unspecified severe protein-energy malnutrition
0.000 0.530 0.470
E42 Marasmic kwashiorkor
0.000 0.530 0.470
E41 Nutritional marasmus
0.000 0.530 0.470
E40 Kwashiorkor
0.000 0.530 0.470
E75.6 Lipid storage disorder, unspecified
0.000 0.535 0.465
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.535 0.465
E75.3 Sphingolipidosis, unspecified
0.000 0.535 0.465
E75.2 Other sphingolipidosis
0.000 0.535 0.465
E75.1 Other gangliosidosis
0.000 0.535 0.465
E75.0 GM2 gangliosidosis
0.000 0.535 0.465
E07.9 Disorder of thyroid, unspecified
0.000 0.535 0.465
E13.9 Without complications
0.000 0.548 0.451
E07.1 Dyshormogenetic goitre
0.000 0.550 0.450
E07.0 Hypersecretion of calcitonin
0.000 0.550 0.450
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.552 0.447
E65 Localised adiposity
0.000 0.555 0.445
M06.8 Other specified rheumatoid arthritis
0.000 0.556 0.443
M06.2 Rheumatoid bursitis
0.000 0.556 0.443
M06.1 Adult-onset Still's disease
0.000 0.556 0.443
E50.9 Vitamin A deficiency, unspecified
0.000 0.564 0.436
E50.8 Other manifestations of vitamin A deficiency
0.000 0.564 0.436
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.564 0.436
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.564 0.436
E50.5 Vitamin A deficiency with night blindness
0.000 0.564 0.436
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.564 0.436
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.564 0.436
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.564 0.436
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.564 0.436
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.564 0.436
E56.9 Vitamin deficiency, unspecified
0.000 0.564 0.436
E56.8 Deficiency of other vitamins
0.000 0.564 0.436
E56.1 Deficiency of vitamin K
0.000 0.564 0.436
E56.0 Deficiency of vitamin E
0.000 0.564 0.436
E63.9 Nutritional deficiency, unspecified
0.000 0.564 0.436
E63.8 Other specified nutritional deficiencies
0.000 0.564 0.436
E63.1 Imbalance of constituents of food intake
0.000 0.564 0.436
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.564 0.436
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.564 0.436
E64.8 Sequelae of other nutritional deficiencies
0.000 0.564 0.436
E64.3 Sequelae of rickets
0.000 0.564 0.436
E64.2 Sequelae of vitamin C deficiency
0.000 0.564 0.436
E64.1 Sequelae of vitamin A deficiency
0.000 0.564 0.436
E64.0 Sequelae of protein-energy malnutrition
0.000 0.564 0.436
E51.9 Thiamine deficiency, unspecified
0.000 0.573 0.427
E51.8 Other manifestations of thiamine deficiency
0.000 0.573 0.427
E51.1 Beriberi
0.000 0.573 0.427
E88.2 Lipomatosis, not elsewhere classified
0.000 0.580 0.420
E88.9 Metabolic disorder, unspecified
0.000 0.582 0.417
E51.2 Wernicke's encephalopathy
0.000 0.586 0.414
K90 Intestinal malabsorption
0.000 0.587 0.413
E46 Unspecified protein-energy malnutrition
0.000 0.592 0.408
E75.5 Other lipid storage disorders
0.000 0.597 0.403
M06.0 Seronegative rheumatoid arthritis
0.000 0.597 0.403
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.598 0.402
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.602 0.398
E67 Other hyperalimentation
0.000 0.602 0.398
E68 Sequelae of hyperalimentation
0.000 0.602 0.398
E55 Vitamin D deficiency
0.000 0.607 0.393
E61.9 Deficiency of nutrient element, unspecified
0.000 0.608 0.392
E61.8 Deficiency of other specified nutrient elements
0.000 0.608 0.392
E61.7 Deficiency of multiple nutrient elements
0.000 0.608 0.392
E61.6 Vanadium deficiency
0.000 0.608 0.392
E61.5 Molybdenum deficiency
0.000 0.608 0.392
E61.4 Chromium deficiency
0.000 0.608 0.392
E61.3 Manganese deficiency
0.000 0.608 0.392
E61.2 Magnesium deficiency
0.000 0.608 0.392
E61.0 Copper deficiency
0.000 0.608 0.392
M06.34 Rheumatoid nodule (Hand)
0.000 0.609 0.391
E88.8 Other specified metabolic disorders
0.000 0.616 0.384
N40 Hyperplasia of prostate
0.372 0.628 0.000
E88.3 Tumour lysis syndrome
0.000 0.640 0.359
M05-M14 Inflammatory polyarthropathies
0.000 0.642 0.358
E11.6 With other specified complications
0.000 0.643 0.356
E07.8 Other specified disorders of thyroid
0.000 0.650 0.350
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.652 0.348
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.652 0.348
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.652 0.348
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.652 0.348
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.652 0.348
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.652 0.348
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.652 0.348
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.652 0.348
M05 Seropositive rheumatoid arthritis
0.000 0.656 0.344
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.658 0.342
M06.38 Rheumatoid nodule (Other)
0.000 0.658 0.342
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.658 0.342
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.658 0.342
M06.33 Rheumatoid nodule (Forearm)
0.000 0.658 0.342
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.658 0.342
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.658 0.342
E44.1 Mild protein-energy malnutrition
0.000 0.663 0.337
E44.0 Moderate protein-energy malnutrition
0.000 0.663 0.337
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.664 0.336
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.668 0.332
E61.1 Iron deficiency
0.000 0.670 0.330
K90.9 Intestinal malabsorption, unspecified
0.000 0.671 0.329
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.671 0.329
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.672 0.328
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.676 0.324
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.680 0.320
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.682 0.318
M06.18 Adult-onset Still's disease (Other)
0.000 0.682 0.318
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.682 0.318
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.682 0.318
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.682 0.318
M06.14 Adult-onset Still's disease (Hand)
0.000 0.682 0.318
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.682 0.318
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.682 0.318
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.682 0.318
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.682 0.318
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.682 0.318
M06.28 Rheumatoid bursitis (Other)
0.000 0.682 0.318
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.682 0.318
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.682 0.318
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.682 0.318
M06.24 Rheumatoid bursitis (Hand)
0.000 0.682 0.318
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.682 0.318
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.682 0.318
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.682 0.318
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.682 0.318
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.682 0.318
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.682 0.318
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.682 0.318
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.682 0.318
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.682 0.318
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.682 0.318
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.682 0.318
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.682 0.318
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.682 0.318
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.682 0.318
K90.3 Pancreatic steatorrhoea
0.000 0.703 0.296
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.703 0.296
K90.1 Tropical sprue
0.000 0.703 0.296
E11.2 With renal complications
0.000 0.707 0.293
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.711 0.289
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.711 0.289
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.711 0.289
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.711 0.289
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.711 0.289
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.711 0.289
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.711 0.289
K90.8 Other intestinal malabsorption
0.000 0.713 0.287
E67.8 Other specified hyperalimentation
0.000 0.714 0.285
E67.3 Hypervitaminosis D
0.000 0.714 0.285
E67.2 Megavitamin-B6 syndrome
0.000 0.714 0.285
E67.1 Hypercarotenaemia
0.000 0.714 0.285
E67.0 Hypervitaminosis A
0.000 0.714 0.285
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.716 0.284
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.718 0.282
E55.0 Rickets, active
0.000 0.718 0.282
M10 Gout
0.000 0.721 0.279
M07 Psoriatic and enteropathic arthropathies
0.000 0.742 0.258
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.743 0.257
M08 Juvenile arthritis
0.000 0.743 0.257
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.746 0.254
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.753 0.247
M12 Other specific arthropathies
0.000 0.753 0.247
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.753 0.247
M05.1 Rheumatoid lung disease
0.000 0.753 0.247
M05.0 Felty's syndrome
0.000 0.753 0.247
M11 Other crystal arthropathies
0.000 0.754 0.246
E83.4 Disorders of magnesium metabolism
0.000 0.754 0.246
M05.8 Other seropositive rheumatoid arthritis
0.000 0.757 0.242
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.759 0.241
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.759 0.241
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.759 0.241
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.759 0.241
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.759 0.241
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.759 0.241
M05.2 Rheumatoid vasculitis
0.000 0.763 0.237
E06 Thyroiditis
0.003 0.765 0.232
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.767 0.233
M10.0 Idiopathic gout
0.000 0.767 0.233
E04 Other non-toxic goitre
0.000 0.770 0.230
M14 Arthropathies in other diseases classified elsewhere
0.000 0.773 0.227
M10.07 Idiopathic gout (Ankle and foot)
0.000 0.792 0.208
M10.4 Other secondary gout
0.000 0.799 0.200
M10.3 Gout due to impairment of renal function
0.000 0.799 0.200
M10.2 Drug-induced gout
0.000 0.799 0.200
M10.1 Lead-induced gout
0.000 0.799 0.200
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.800 0.200
M12.2 Villonodular synovitis (pigmented)
0.000 0.811 0.189
M07.3 Other psoriatic arthropathies
0.000 0.813 0.186
M07.6 Other enteropathic arthropathies
0.000 0.815 0.185
M07.5 Arthropathy in ulcerative colitis
0.000 0.815 0.185
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.815 0.185
M07.2 Psoriatic spondylitis
0.000 0.815 0.185
M07.1 Arthritis mutilans
0.000 0.815 0.185
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.815 0.185
M08.9 Juvenile arthritis, unspecified
0.000 0.815 0.184
M08.8 Other juvenile arthritis
0.000 0.815 0.184
M08.4 Pauciarticular juvenile arthritis
0.000 0.815 0.184
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.815 0.184
M08.2 Juvenile arthritis with systemic onset
0.000 0.815 0.184
M08.1 Juvenile ankylosing spondylitis
0.000 0.815 0.184
M08.0 Juvenile rheumatoid arthritis
0.000 0.815 0.184
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.815 0.184
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.815 0.184
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.815 0.184
M09.0 Juvenile arthritis in psoriasis
0.000 0.815 0.184
M10.9 Gout, unspecified
0.000 0.817 0.183
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.823 0.177
M12.5 Traumatic arthropathy
0.000 0.823 0.177
M12.4 Intermittent hydrarthrosis
0.000 0.823 0.177
M12.1 Kaschin-Beck disease
0.000 0.823 0.177
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.823 0.177
M05.09 Felty's syndrome (Site unspecified)
0.000 0.823 0.177
M05.08 Felty's syndrome (Other)
0.000 0.823 0.177
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.823 0.177
M05.06 Felty's syndrome (Lower leg)
0.000 0.823 0.177
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.823 0.177
M05.04 Felty's syndrome (Hand)
0.000 0.823 0.177
M05.03 Felty's syndrome (Forearm)
0.000 0.823 0.177
M05.02 Felty's syndrome (Upper arm)
0.000 0.823 0.177
M05.01 Felty's syndrome (Shoulder region)
0.000 0.823 0.177
M05.00 Felty's syndrome (Multiple sites)
0.000 0.823 0.177
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.823 0.177
M05.18 Rheumatoid lung disease (Other)
0.000 0.823 0.177
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.823 0.177
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.823 0.177
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.823 0.177
M05.14 Rheumatoid lung disease (Hand)
0.000 0.823 0.177
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.823 0.177
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.823 0.177
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.823 0.177
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.823 0.177
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.823 0.177
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.823 0.177
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.823 0.177
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.823 0.177
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.823 0.177
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.823 0.177
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.823 0.177
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.823 0.177
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.823 0.177
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.823 0.177
M11.9 Crystal arthropathy, unspecified
0.000 0.823 0.176
M11.8 Other specified crystal arthropathies
0.000 0.823 0.176
M11.1 Familial chondrocalcinosis
0.000 0.823 0.176
M11.0 Hydroxyapatite deposition disease
0.000 0.823 0.176
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.826 0.174
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.826 0.174
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.826 0.174
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.826 0.174
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.826 0.174
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.826 0.174
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.826 0.174
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.826 0.174
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.826 0.174
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.830 0.170
M05.28 Rheumatoid vasculitis (Other)
0.000 0.830 0.170
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.000 0.830 0.170
M05.26 Rheumatoid vasculitis (Lower leg)
0.000 0.830 0.170
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.000 0.830 0.170
M05.24 Rheumatoid vasculitis (Hand)
0.000 0.830 0.170
M05.23 Rheumatoid vasculitis (Forearm)
0.000 0.830 0.170
M05.22 Rheumatoid vasculitis (Upper arm)
0.000 0.830 0.170
M05.21 Rheumatoid vasculitis (Shoulder region)
0.000 0.830 0.170
M05.20 Rheumatoid vasculitis (Multiple sites)
0.000 0.830 0.170
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.830 0.169
E06.4 Drug-induced thyroiditis
0.002 0.831 0.167
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.002 0.831 0.167
E06.1 Subacute thyroiditis
0.002 0.831 0.167
E06.0 Acute thyroiditis
0.002 0.831 0.167
M10.09 Idiopathic gout (Site unspecified)
0.000 0.832 0.167
M10.08 Idiopathic gout (Other)
0.000 0.832 0.167
M10.06 Idiopathic gout (Lower leg)
0.000 0.832 0.167
M10.05 Idiopathic gout (Pelvic region and thigh)
0.000 0.832 0.167
M10.04 Idiopathic gout (Hand)
0.000 0.832 0.167
M10.03 Idiopathic gout (Forearm)
0.000 0.832 0.167
M10.02 Idiopathic gout (Upper arm)
0.000 0.832 0.167
M10.01 Idiopathic gout (Shoulder region)
0.000 0.832 0.167
M11.2 Other chondrocalcinosis
0.000 0.834 0.165
E04.8 Other specified non-toxic goitre
0.000 0.835 0.165
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.837 0.163
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.837 0.163
M14.4 Arthropathy in amyloidosis
0.000 0.837 0.163

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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