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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3918149
log Bayes Factor = 18.619
Chromosome 6   position 32,936,373  (GRCh37) Explore rs3918149 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
L40.8 Other psoriasis
0.847 0.153 0.000
J45.9 Asthma, unspecified
0.000 0.159 0.841
J47 Bronchiectasis
0.000 0.162 0.838
L40.0 Psoriasis vulgaris
0.835 0.165 0.000
J45 Asthma
0.000 0.179 0.821
J40-J47 Chronic lower respiratory diseases
0.000 0.188 0.812
K90 Intestinal malabsorption
0.000 0.235 0.765
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
L40.1 Generalised pustular psoriasis
0.717 0.283 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.291 0.709
E10.9 Without complications
0.000 0.335 0.665
E10 Insulin-dependent diabetes mellitus
0.000 0.339 0.661
E10.3 With ophthalmic complications
0.000 0.354 0.646
J42 Unspecified chronic bronchitis
0.000 0.377 0.623
J45.8 Mixed asthma
0.000 0.411 0.589
J45.1 Nonallergic asthma
0.000 0.411 0.589
J41 Simple and mucopurulent chronic bronchitis
0.000 0.418 0.582
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.419 0.581
E05.9 Thyrotoxicosis, unspecified
0.000 0.421 0.579
E00-E07 Disorders of thyroid gland
0.000 0.429 0.571
E10.1 With ketoacidosis
0.000 0.430 0.570
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.433 0.567
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.439 0.561
E10-E14 Diabetes mellitus
0.000 0.447 0.553
E03 Other hypothyroidism
0.000 0.448 0.552
J43 Emphysema
0.000 0.450 0.550
K90.8 Other intestinal malabsorption
0.000 0.452 0.548
K90.3 Pancreatic steatorrhoea
0.000 0.452 0.548
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.452 0.548
K90.1 Tropical sprue
0.000 0.452 0.548
E03.9 Hypothyroidism, unspecified
0.000 0.456 0.544
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.456 0.544
E10.4 With neurological complications
0.000 0.477 0.523
J45.0 Predominantly allergic asthma
0.000 0.490 0.510
E10.0 With coma
0.000 0.497 0.503
E10.5 With peripheral circulatory complications
0.000 0.501 0.499
J46 Status asthmaticus
0.000 0.504 0.496
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.482 0.518 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.475 0.525 0.000
E10.7 With multiple complications
0.000 0.526 0.474
E10.6 With other specified complications
0.000 0.526 0.474
L40-L45 Papulosquamous disorders
0.473 0.527 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.466 0.534 0.000
T42.4 Benzodiazepines
0.466 0.534 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.465 0.535 0.000
E10.8 With unspecified complications
0.000 0.542 0.458
E07 Other disorders of thyroid
0.000 0.551 0.449
T43.3 Phenothiazine antipsychotics and neuroleptics
0.440 0.560 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.563 0.437
E40-E46 Malnutrition
0.000 0.571 0.429
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.419 0.581 0.000
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.583 0.417
J41.1 Mucopurulent chronic bronchitis
0.000 0.583 0.417
J41.0 Simple chronic bronchitis
0.000 0.583 0.417
E05.8 Other thyrotoxicosis
0.000 0.583 0.416
E05.5 Thyroid crisis or storm
0.000 0.583 0.416
E05.4 Thyrotoxicosis factitia
0.000 0.583 0.416
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.583 0.416
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.583 0.416
T43.5 Other and unspecified antipsychotics and neuroleptics
0.411 0.589 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.590 0.410
E00 Congenital iodine-deficiency syndrome
0.000 0.590 0.410
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.590 0.410
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.590 0.410
E03.8 Other specified hypothyroidism
0.000 0.603 0.397
E12 Malnutrition-related diabetes mellitus
0.000 0.604 0.396
E03.5 Myxoedema coma
0.000 0.604 0.396
E03.4 Atrophy of thyroid (acquired)
0.000 0.604 0.396
E03.3 Postinfectious hypothyroidism
0.000 0.604 0.396
E03.1 Congenital hypothyroidism without goitre
0.000 0.604 0.396
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.604 0.396
J43.8 Other emphysema
0.000 0.605 0.395
J43.1 Panlobular emphysema
0.000 0.605 0.395
J43.0 MacLeod's syndrome
0.000 0.605 0.395
J43.9 Emphysema, unspecified
0.000 0.608 0.392
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.389 0.611 0.000
T42.1 Iminostilbenes
0.388 0.612 0.000
E10.2 With renal complications
0.000 0.615 0.385
L43 Lichen planus
0.384 0.616 0.000
T43.2 Other and unspecified antidepressants
0.384 0.616 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.382 0.618 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.381 0.619 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.377 0.623 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.377 0.623 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.623 0.377
E65 Localised adiposity
0.000 0.625 0.374
T46 Poisoning by agents primarily affecting the cardiovascular system
0.369 0.631 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.367 0.633 0.000
J43.2 Centrilobular emphysema
0.000 0.634 0.366
J40 Bronchitis, not specified as acute or chronic
0.000 0.642 0.358
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.357 0.643 0.000
E50-E64 Other nutritional deficiencies
0.000 0.645 0.355
T42.0 Hydantoin derivatives
0.355 0.645 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.654 0.346
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.346 0.654 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.346 0.654 0.000
T42.3 Barbiturates
0.346 0.654 0.000
T42.2 Succinimides and oxazolidinediones
0.346 0.654 0.000
T38.1 Thyroid hormones and substitutes
0.343 0.657 0.000
T36 Poisoning by systemic antibiotics
0.341 0.658 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.341 0.659 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.341 0.659 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.341 0.659 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.341 0.659 0.000
L44 Other papulosquamous disorders
0.339 0.661 0.000
L41 Parapsoriasis
0.339 0.661 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.339 0.661 0.000
T43.6 Psychostimulants with abuse potential
0.335 0.665 0.000
T43.9 Psychotropic drug, unspecified
0.334 0.666 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.334 0.666 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.334 0.666 0.000
L43.9 Lichen planus, unspecified
0.334 0.666 0.000
E13 Other specified diabetes mellitus
0.000 0.666 0.333
T39.1 4-Aminophenol derivatives
0.331 0.669 0.000
E06 Thyroiditis
0.000 0.675 0.325
E07.1 Dyshormogenetic goitre
0.000 0.678 0.322
E07.0 Hypersecretion of calcitonin
0.000 0.678 0.322
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.681 0.319
T50.9 Other and unspecified drugs, medicaments and biological substances
0.314 0.686 0.000
E67 Other hyperalimentation
0.000 0.686 0.313
E68 Sequelae of hyperalimentation
0.000 0.686 0.313
E16 Other disorders of pancreatic internal secretion
0.000 0.687 0.313
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.313 0.687 0.000
T45.0 Antiallergic and antiemetic drugs
0.312 0.688 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.689 0.310
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.692 0.307
E45 Retarded development following protein-energy malnutrition
0.000 0.692 0.307
E43 Unspecified severe protein-energy malnutrition
0.000 0.692 0.307
E42 Marasmic kwashiorkor
0.000 0.692 0.307
E41 Nutritional marasmus
0.000 0.692 0.307
E40 Kwashiorkor
0.000 0.692 0.307
L42 Pityriasis rosea
0.304 0.696 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.302 0.698 0.000
T38.9 Other and unspecified hormone antagonists
0.301 0.699 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.301 0.699 0.000
T38.7 Androgens and anabolic congeners
0.301 0.699 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.301 0.699 0.000
T38.5 Other oestrogens and progestogens
0.301 0.699 0.000
T38.4 Oral contraceptives
0.301 0.699 0.000
T38.2 Antithyroid drugs
0.301 0.699 0.000
T38.0 Glucocorticoids and synthetic analogues
0.301 0.699 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.300 0.700 0.000
E07.8 Other specified disorders of thyroid
0.000 0.704 0.296
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.706 0.294
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.706 0.294
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.706 0.294
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.706 0.294
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.706 0.294
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.706 0.294
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.706 0.294
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.706 0.294
E15 Nondiabetic hypoglycaemic coma
0.000 0.706 0.294
E14 Unspecified diabetes mellitus
0.000 0.708 0.292
T47.1 Other antacids and anti-gastric-secretion drugs
0.289 0.711 0.000
E66 Obesity
0.000 0.715 0.285
E12.9 Without complications
0.000 0.716 0.284
E12.8 With unspecified complications
0.000 0.716 0.284
E12.7 With multiple complications
0.000 0.716 0.284
E12.6 With other specified complications
0.000 0.716 0.284
E12.5 With peripheral circulatory complications
0.000 0.716 0.284
E12.4 With neurological complications
0.000 0.716 0.284
E12.3 With ophthalmic complications
0.000 0.716 0.284
E12.2 With renal complications
0.000 0.716 0.284
E12.1 With ketoacidosis
0.000 0.716 0.284
E12.0 With coma
0.000 0.716 0.284
T39.0 Salicylates
0.283 0.717 0.000
T45.5 Anticoagulants
0.281 0.719 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.279 0.721 0.000
T45.8 Other primarily systemic and haematological agents
0.279 0.721 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.279 0.721 0.000
T45.6 Fibrinolysis-affecting drugs
0.279 0.721 0.000
T45.4 Iron and its compounds
0.279 0.721 0.000
T45.3 Enzymes, not elsewhere classified
0.279 0.721 0.000
T45.2 Vitamins, not elsewhere classified
0.279 0.721 0.000
L43.3 Subacute (active) lichen planus
0.276 0.724 0.000
L43.2 Lichenoid drug reaction
0.276 0.724 0.000
L43.1 Bullous lichen planus
0.276 0.724 0.000
L43.0 Hypertrophic lichen planus
0.276 0.724 0.000
T50.8 Diagnostic agents
0.273 0.726 0.000
T50.7 Analeptics and opioid receptor antagonists
0.273 0.726 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.273 0.726 0.000
T50.5 Appetite depressants
0.273 0.726 0.000
T50.4 Drugs affecting uric acid metabolism
0.273 0.726 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.273 0.726 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.273 0.726 0.000
T50.1 Loop [high-ceiling] diuretics
0.273 0.726 0.000
T50.0 Mineralocorticoids and their antagonists
0.273 0.726 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.273 0.727 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.271 0.729 0.000
T39.4 Antirheumatics, not elsewhere classified
0.270 0.730 0.000
T39.2 Pyrazolone derivatives
0.270 0.730 0.000
E66.8 Other obesity
0.000 0.735 0.265
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.265 0.735 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.265 0.735 0.000
T46.7 Peripheral vasodilators
0.265 0.735 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.265 0.735 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.265 0.735 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.265 0.735 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.263 0.737 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.263 0.737 0.000
T47.7 Emetics
0.263 0.737 0.000
T47.6 Antidiarrhoeal drugs
0.263 0.737 0.000
T47.5 Digestants
0.263 0.737 0.000
T47.4 Other laxatives
0.263 0.737 0.000
T47.3 Saline and osmotic laxatives
0.263 0.737 0.000
T47.2 Stimulant laxatives
0.263 0.737 0.000
T47.0 Histamine H(2)-receptor antagonists
0.263 0.737 0.000
E55 Vitamin D deficiency
0.000 0.738 0.262
T46.1 Calcium-channel blockers
0.257 0.743 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.257 0.743 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.744 0.256
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.745 0.255
E63 Other nutritional deficiencies
0.000 0.745 0.255
E56 Other vitamin deficiencies
0.000 0.745 0.255
E51 Thiamine deficiency
0.000 0.745 0.255
E50 Vitamin A deficiency
0.000 0.745 0.255
E60 Dietary zinc deficiency
0.000 0.745 0.255
E59 Dietary selenium deficiency
0.000 0.745 0.255
E58 Dietary calcium deficiency
0.000 0.745 0.255
E54 Ascorbic acid deficiency
0.000 0.745 0.255
E52 Niacin deficiency [pellagra]
0.000 0.745 0.255
T46.4 Angiotensin-converting-enzyme inhibitors
0.249 0.751 0.000
L43.8 Other lichen planus
0.248 0.752 0.000
E04 Other non-toxic goitre
0.000 0.753 0.247
T36.0 Penicillins
0.246 0.754 0.000
T36.9 Systemic antibiotic, unspecified
0.245 0.755 0.000
T36.8 Other systemic antibiotics
0.245 0.755 0.000
T36.7 Antifungal antibiotics, systemically used
0.245 0.755 0.000
T36.6 Rifamycins
0.245 0.755 0.000
T36.5 Aminoglycosides
0.245 0.755 0.000
T36.4 Tetracyclines
0.245 0.755 0.000
T36.3 Macrolides
0.245 0.755 0.000
T36.2 Chloramphenicol group
0.245 0.755 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.245 0.755 0.000
E53 Deficiency of other B group vitamins
0.000 0.755 0.245
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.244 0.755 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.244 0.755 0.000
T37.5 Antiviral drugs
0.244 0.755 0.000
T37.4 Anthelminthics
0.244 0.755 0.000
T37.3 Other antiprotozoal drugs
0.244 0.755 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.244 0.755 0.000
T37.1 Antimycobacterial drugs
0.244 0.755 0.000
T37.0 Sulphonamides
0.244 0.755 0.000
T41.5 Therapeutic gases
0.244 0.755 0.000
T41.4 Anaesthetic, unspecified
0.244 0.755 0.000
T41.3 Local anaesthetics
0.244 0.755 0.000
T41.2 Other and unspecified general anaesthetics
0.244 0.755 0.000
T41.1 Intravenous anaesthetics
0.244 0.755 0.000
T41.0 Inhaled anaesthetics
0.244 0.755 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.244 0.755 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.244 0.755 0.000
T48.5 Anti-common-cold drugs
0.244 0.755 0.000
T48.4 Expectorants
0.244 0.755 0.000
T48.3 Antitussives
0.244 0.755 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.244 0.755 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.244 0.755 0.000
T48.0 Oxytocic drugs
0.244 0.755 0.000
T49.9 Topical agent, unspecified
0.244 0.755 0.000
T49.8 Other topical agents
0.244 0.755 0.000
T49.7 Dental drugs, topically applied
0.244 0.755 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.244 0.755 0.000
T49.5 Ophthalmological drugs and preparations
0.244 0.755 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.244 0.755 0.000
T49.3 Emollients, demulcents and protectants
0.244 0.755 0.000
T49.2 Local astringents and local detergents
0.244 0.755 0.000
T49.1 Antipruritics
0.244 0.755 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.244 0.755 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.243 0.756 0.000
L41.9 Parapsoriasis, unspecified
0.243 0.757 0.000
L41.8 Other parapsoriasis
0.243 0.757 0.000
L41.5 Retiform parapsoriasis
0.243 0.757 0.000
L41.4 Large plaque parapsoriasis
0.243 0.757 0.000
L41.3 Small plaque parapsoriasis
0.243 0.757 0.000
L41.2 Lymphomatoid papulosis
0.243 0.757 0.000
L41.1 Pityriasis lichenoides chronica
0.243 0.757 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.243 0.757 0.000
L44.9 Papulosquamous disorder, unspecified
0.243 0.757 0.000
L44.8 Other specified papulosquamous disorders
0.243 0.757 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.243 0.757 0.000
L44.3 Lichen ruber moniliformis
0.243 0.757 0.000
L44.2 Lichen striatus
0.243 0.757 0.000
L44.1 Lichen nitidus
0.243 0.757 0.000
L44.0 Pityriasis rubra pilaris
0.243 0.757 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.243 0.757 0.000
E14.3 With ophthalmic complications
0.000 0.758 0.242
E13.8 With unspecified complications
0.000 0.761 0.239
E13.7 With multiple complications
0.000 0.761 0.239
E13.6 With other specified complications
0.000 0.761 0.239
E13.5 With peripheral circulatory complications
0.000 0.761 0.239
E13.4 With neurological complications
0.000 0.761 0.239
E13.3 With ophthalmic complications
0.000 0.761 0.239
E13.2 With renal complications
0.000 0.761 0.239
E13.1 With ketoacidosis
0.000 0.761 0.239
E13.0 With coma
0.000 0.761 0.239
E20-E35 Disorders of other endocrine glands
0.000 0.765 0.235
E06.5 Other chronic thyroiditis
0.000 0.767 0.233
E06.4 Drug-induced thyroiditis
0.000 0.767 0.233
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.767 0.233
E06.1 Subacute thyroiditis
0.000 0.767 0.233
E06.0 Acute thyroiditis
0.000 0.767 0.233
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.229 0.771 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.226 0.774 0.000
E67.8 Other specified hyperalimentation
0.000 0.775 0.225
E67.3 Hypervitaminosis D
0.000 0.775 0.225
E67.2 Megavitamin-B6 syndrome
0.000 0.775 0.225
E67.1 Hypercarotenaemia
0.000 0.775 0.225
E67.0 Hypervitaminosis A
0.000 0.775 0.225
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.775 0.225
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.775 0.225
E16.4 Abnormal secretion of gastrin
0.000 0.775 0.225
E16.3 Increased secretion of glucagon
0.000 0.775 0.225
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.775 0.225
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.224 0.775 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.224 0.775 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.224 0.775 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.224 0.775 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.224 0.775 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.224 0.775 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.224 0.775 0.000
T44.0 Anticholinesterase agents
0.224 0.775 0.000
E61 Deficiency of other nutrient elements
0.000 0.778 0.222
E44.1 Mild protein-energy malnutrition
0.000 0.779 0.221
E44.0 Moderate protein-energy malnutrition
0.000 0.779 0.221
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.784 0.216
E06.9 Thyroiditis, unspecified
0.000 0.790 0.210
E14.7 With multiple complications
0.000 0.790 0.209
E14.6 With other specified complications
0.000 0.790 0.209
E14.5 With peripheral circulatory complications
0.000 0.790 0.209
E14.4 With neurological complications
0.000 0.790 0.209
E14.2 Withrenal complications
0.000 0.790 0.209
E14.1 With ketoacidosis
0.000 0.790 0.209
E14.0 With coma
0.000 0.790 0.209
E04.2 Non-toxic multinodular goitre
0.000 0.792 0.208
E16.1 Other hypoglycaemia
0.000 0.795 0.205
E66.1 Drug-induced obesity
0.000 0.795 0.205
E14.8 With unspecified complications
0.000 0.803 0.197
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.804 0.196
E55.9 Vitamin D deficiency, unspecified
0.000 0.805 0.195
T40.6 Other and unspecified narcotics
0.195 0.805 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.195 0.805 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.806 0.194
E55.0 Rickets, active
0.000 0.812 0.188
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.185 0.815 0.000
T40.8 Lysergide [LSD]
0.185 0.815 0.000
T40.7 Cannabis (derivatives)
0.185 0.815 0.000
T40.5 Cocaine
0.185 0.815 0.000
T40.3 Methadone
0.185 0.815 0.000
T40.1 Heroin
0.185 0.815 0.000
T40.0 Opium
0.185 0.815 0.000
J44 Other chronic obstructive pulmonary disease
0.000 0.816 0.184
E06.3 Autoimmune thyroiditis
0.000 0.817 0.183
E50.9 Vitamin A deficiency, unspecified
0.000 0.817 0.183
E50.8 Other manifestations of vitamin A deficiency
0.000 0.817 0.183
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.817 0.183
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.817 0.183
E50.5 Vitamin A deficiency with night blindness
0.000 0.817 0.183
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.817 0.183
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.817 0.183
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.817 0.183
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.817 0.183
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.817 0.183
E51.9 Thiamine deficiency, unspecified
0.000 0.817 0.183
E51.8 Other manifestations of thiamine deficiency
0.000 0.817 0.183
E51.2 Wernicke's encephalopathy
0.000 0.817 0.183
E51.1 Beriberi
0.000 0.817 0.183
E56.9 Vitamin deficiency, unspecified
0.000 0.817 0.183
E56.8 Deficiency of other vitamins
0.000 0.817 0.183
E56.1 Deficiency of vitamin K
0.000 0.817 0.183
E56.0 Deficiency of vitamin E
0.000 0.817 0.183
E63.9 Nutritional deficiency, unspecified
0.000 0.817 0.183
E63.8 Other specified nutritional deficiencies
0.000 0.817 0.183
E63.1 Imbalance of constituents of food intake
0.000 0.817 0.183
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.817 0.183
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.817 0.183
E64.8 Sequelae of other nutritional deficiencies
0.000 0.817 0.183
E64.3 Sequelae of rickets
0.000 0.817 0.183
E64.2 Sequelae of vitamin C deficiency
0.000 0.817 0.183
E64.1 Sequelae of vitamin A deficiency
0.000 0.817 0.183
E64.0 Sequelae of protein-energy malnutrition
0.000 0.817 0.183
E04.8 Other specified non-toxic goitre
0.000 0.823 0.177
E13.9 Without complications
0.000 0.823 0.176
E66.0 Obesity due to excess calories
0.000 0.824 0.176
E53.9 Vitamin B deficiency, unspecified
0.000 0.824 0.176
E53.1 Pyridoxine deficiency
0.000 0.824 0.176
E53.0 Riboflavin deficiency
0.000 0.824 0.176
E26 Hyperaldosteronism
0.000 0.829 0.171
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.830 0.170
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.831 0.168
E32 Diseases of thymus
0.000 0.831 0.168
E31 Polyglandular dysfunction
0.000 0.831 0.168
E30 Disorders of puberty, not elsewhere classified
0.000 0.831 0.168
E53.8 Deficiency of other specified B group vitamins
0.000 0.834 0.166
E21.0 Primary hyperparathyroidism
0.000 0.835 0.165
E28 Ovarian dysfunction
0.000 0.836 0.164
E22 Hyperfunction of pituitary gland
0.000 0.837 0.163
E27 Other disorders of adrenal gland
0.000 0.838 0.162
E61.9 Deficiency of nutrient element, unspecified
0.000 0.840 0.159
E61.8 Deficiency of other specified nutrient elements
0.000 0.840 0.159
E61.7 Deficiency of multiple nutrient elements
0.000 0.840 0.159
E61.6 Vanadium deficiency
0.000 0.840 0.159
E61.5 Molybdenum deficiency
0.000 0.840 0.159
E61.4 Chromium deficiency
0.000 0.840 0.159
E61.3 Manganese deficiency
0.000 0.840 0.159
E61.2 Magnesium deficiency
0.000 0.840 0.159
E61.0 Copper deficiency
0.000 0.840 0.159
E29 Testicular dysfunction
0.000 0.843 0.157
E34 Other endocrine disorders
0.000 0.845 0.155
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.845 0.155
E21.4 Other specified disorders of parathyroid gland
0.000 0.845 0.155
E21.2 Other hyperparathyroidism
0.000 0.845 0.155
T40.2 Other opioids
0.146 0.854 0.000
E20 Hypoparathyroidism
0.000 0.856 0.144
E25 Adrenogenital disorders
0.000 0.857 0.142
E27.1 Primary adrenocortical insufficiency
0.000 0.857 0.143
E24 Cushing's syndrome
0.000 0.860 0.139
T40.4 Other synthetic narcotics
0.139 0.861 0.000
E27.9 Disorder of adrenal gland, unspecified
0.000 0.861 0.138
M07.39 Other psoriatic arthropathies (Site unspecified)
0.138 0.862 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.863 0.137
M07.3 Other psoriatic arthropathies
0.136 0.864 0.000
E04.1 Non-toxic single thyroid nodule
0.000 0.865 0.135
M07.30 Other psoriatic arthropathies (Multiple sites)
0.134 0.866 0.000
E61.1 Iron deficiency
0.000 0.873 0.127
E26.0 Primary hyperaldosteronism
0.000 0.875 0.125
E22.1 Hyperprolactinaemia
0.000 0.877 0.123
E26.9 Hyperaldosteronism, unspecified
0.000 0.877 0.122
E26.8 Other hyperaldosteronism
0.000 0.877 0.122
E26.1 Secondary hyperaldosteronism
0.000 0.877 0.122
E30.9 Disorder of puberty, unspecified
0.000 0.879 0.121
E30.8 Other disorders of puberty
0.000 0.879 0.121
E30.1 Precocious puberty
0.000 0.879 0.121
E30.0 Delayed puberty
0.000 0.879 0.121
E31.9 Polyglandular dysfunction, unspecified
0.000 0.879 0.121
E31.8 Other polyglandular dysfunction
0.000 0.879 0.121
E31.1 Polyglandular hyperfunction
0.000 0.879 0.121
E31.0 Autoimmune polyglandular failure
0.000 0.879 0.121
E32.9 Disease of thymus, unspecified
0.000 0.879 0.121
E32.8 Other diseases of thymus
0.000 0.879 0.121
E32.1 Abscess of thymus
0.000 0.879 0.121
E32.0 Persistent hyperplasia of thymus
0.000 0.879 0.121
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.879 0.121
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.879 0.121
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.879 0.121
E28.3 Primary ovarian failure
0.000 0.881 0.119
E28.9 Ovarian dysfunction, unspecified
0.000 0.882 0.118
E28.8 Other ovarian dysfunction
0.000 0.882 0.118
E28.1 Androgen excess
0.000 0.882 0.118
E28.0 Oestrogen excess
0.000 0.882 0.118
E22.0 Acromegaly and pituitary gigantism
0.000 0.883 0.117
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.883 0.117
E22.8 Other hyperfunction of pituitary gland
0.000 0.883 0.117
E27.5 Adrenomedullary hyperfunction
0.000 0.883 0.116
E27.0 Other adrenocortical overactivity
0.000 0.883 0.116
M07.36 Other psoriatic arthropathies (Lower leg)
0.114 0.886 0.000
E04.9 Non-toxic goitre, unspecified
0.000 0.887 0.113
E29.9 Testicular dysfunction, unspecified
0.000 0.887 0.112
E29.8 Other testicular dysfunction
0.000 0.887 0.112
E29.0 Testicular hyperfunction
0.000 0.887 0.112
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.112 0.888 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.888 0.112
E34.8 Other specified endocrine disorders
0.000 0.889 0.111
E34.5 Androgen resistance syndrome
0.000 0.889 0.111
E34.4 Constitutional tall stature
0.000 0.889 0.111
E34.3 Short stature, not elsewhere classified
0.000 0.889 0.111
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.889 0.111
E34.1 Other hypersecretion of intestinal hormones
0.000 0.889 0.111
E34.0 Carcinoid syndrome
0.000 0.889 0.111
E04.0 Non-toxic diffuse goitre
0.001 0.889 0.110
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.896 0.104
E20.8 Other hypoparathyroidism
0.000 0.896 0.103
E20.1 Pseudohypoparathyroidism
0.000 0.896 0.103
E20.0 Idiopathic hypoparathyroidism
0.000 0.896 0.103
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.897 0.103
E25.9 Adrenogenital disorder, unspecified
0.000 0.897 0.102
E25.8 Other adrenogenital disorders
0.000 0.897 0.102
E29.1 Testicular hypofunction
0.000 0.899 0.101
E27.8 Other specified disorders of adrenal gland
0.000 0.900 0.100
E24.8 Other Cushing's syndrome
0.000 0.900 0.100
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.900 0.100
E24.3 Ectopic ACTH syndrome
0.000 0.900 0.100
E24.1 Nelson's syndrome
0.000 0.900 0.100
E24.0 Pituitary-dependent Cushing's disease
0.000 0.900 0.100
M07.38 Other psoriatic arthropathies (Other)
0.098 0.902 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.098 0.902 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.098 0.902 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.098 0.902 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.098 0.902 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.098 0.902 0.000
E34.9 Endocrine disorder, unspecified
0.000 0.902 0.097
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.908 0.092
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.909 0.091
E24.9 Cushing's syndrome, unspecified
0.000 0.911 0.089
E24.2 Drug-induced Cushing's syndrome
0.000 0.914 0.086
M06.9 Rheumatoid arthritis, unspecified
0.000 0.916 0.084

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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